US3368549A - Diagnostic swabs - Google Patents

Diagnostic swabs Download PDF

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Publication number
US3368549A
US3368549A US404852A US40485264A US3368549A US 3368549 A US3368549 A US 3368549A US 404852 A US404852 A US 404852A US 40485264 A US40485264 A US 40485264A US 3368549 A US3368549 A US 3368549A
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United States
Prior art keywords
culture medium
organism
micro
present
swab
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
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US404852A
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English (en)
Inventor
Fred S Barr
Galen F Collins
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S E MASSENGILL CO
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S E MASSENGILL CO
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Filing date
Publication date
Application filed by S E MASSENGILL CO filed Critical S E MASSENGILL CO
Priority to US404852A priority Critical patent/US3368549A/en
Priority to GB42175/65A priority patent/GB1082459A/en
Priority to DE6604278U priority patent/DE6604278U/de
Priority to DE19651492038 priority patent/DE1492038A1/de
Priority to NL6513509A priority patent/NL6513509A/xx
Application granted granted Critical
Publication of US3368549A publication Critical patent/US3368549A/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B10/00—Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
    • A61B10/0096—Casings for storing test samples
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F13/00—Bandages or dressings; Absorbent pads
    • A61F13/15—Absorbent pads, e.g. sanitary towels, swabs or tampons for external or internal application to the body; Supporting or fastening means therefor; Tampon applicators
    • A61F13/38—Swabs having a stick-type handle, e.g. cotton tips

Definitions

  • the present invention relates to diagnostic swa-bs, and more particularly to swabs or swab-like structures which permit the direct contacting thereof with an area of a patients body (animal or human) suspected of possibly harboring a pathogenic micro-organism and direct culturing of the same for determination of whether or not the micro-organism was, indeed, present.
  • the present invention relates to such arrangement which permits the physician the possibility of avoiding the step of transferring the smear to a tube or plate containing a culture medium, While nevertheless providing the possibility of culturing the smear and thereby determining whether or not the suspected micro-organism was present in the host animal or human.
  • a physician will contact an area of suspected infectation by a micro-organism, for example the throat or vagina of a patient, with a swab (the socalled taking of a smear) and then transferring the same to a separate prepared tube (slant) or plate of cultured media for the growing of the micro-organism, where-after the tube or plate is generally incubated, so that the physician can subsequently determine whether or not a pathogenic micro-organism was present, is well known.
  • a swab the socalled taking of a smear
  • the present invention mainly comprises a testing assembly for determination of the presence or absence or a micro-organism in an area of a host animal or human patient, said testing assembly comprising a sterile container, and culture medium carrying means removeably housed in the interior of the container so that the culture medium carrying means can be removed from the container to be placed in contact with the area of suspected infestation of a micro-organism and then replaced in the container for incubation.
  • the present invention further relates to a device for 3,368,549 Patented Feb. 13, 1968 making smears of a patients area of suspected infestation of a micro-organism and determining whether or not the micro-organism is present, said device comprising an elongated support, and culture medium carrying means carried by the support at an end portion thereof to be placed in contact with the area of suspected infestation so that thereafter the same can be incubated with the means without requiring transfer to a separate culture medium or container containing a separate culture medium.
  • FIG. '1 illustrates a container and cap for holding the swab device in sterile condition
  • FIG. 2 illustrates a swab in accordance with one embodiment of the invention.
  • FIG. 2a illustrates another embodiment of a swab in accordance with the present invention.
  • FIG. 1 shows a tube 10 provided with threads 11 so that a cap 12 can be securely closed onthe tube.
  • a tube 10 provided with threads 11 so that a cap 12 can be securely closed onthe tube.
  • an elongated handle or stick 13 which may be, for example, of wood or plastic, is provided with a mound or batting of absorbent cotton or the like 14 onto which is moulded the culture medium 15.
  • This swab assembly is then sterilized and kept in the tube 10, which is also sterilized, with the cap 12 thereon until it is ready for use.
  • the cap 12 When ready for use, the cap 12 is removed, the swab taken from the tube and the culture medium end placed in contact with the area of the patient suspected of carrying the pathogenic microorganism, for example the throat, ear, nose, vagina, or the like, and the swab is then reinserted into the tube and incubated, for example at a temperature of 25 C. to 37 C. The presence of the micro-organism is determined after the incubation period.
  • the pathogenic microorganism for example the throat, ear, nose, vagina, or the like
  • an elongated handle 16 which is preferably in this case made of plastic, is provided with a lateral projection 17.
  • the lateral projection as shown in FIG. 2a provides for a T-shaped assembly.
  • the lateral projection can also be in the form of an arrowhead or any other convenient shape.
  • This lateral projection permits the culture medium 18 to be directly moulded onto the end of the handle 16 and prevents slipping off of the moulded solidified culture medium therefrom.
  • the resulting swab can be used in exactly the same manner as the swab of FIG. 2 for determination of the presence or absence of a micro organism in the area at which the smear is made. The smear is made by rubbing the swab directly on the surface of the tissue to be tested.
  • changes are made in the normal culture medium for two purpses: (1) To-provide greater solidity which permits moulding of the cultured medium onto the stick or the like, and (2) the provision in the culture medium of an indicator which provides a characteristic color in the presence of the suspected pathogenic micro-organism, plus an antibiotic which will inhibit the growth of bacteria other than bacteria which will give the characteristic color with the indicator.
  • Normal culture media contain as solidifying agent up to about 2% of agar. In accordance with thepresent invention, however, it is preferred to provide about 3% of agar in the culture media inorderto provide greater solidity and to make it possibleto mould the media onto the applicator and to. prevent excessive breakage in handling and exposure to the culture..'Somewhat-morethan 3% of agar may be provided. However, it has been found that best results are obtained by the use of approximately 3% of agar in the culture media.
  • a growth of Candida albicans will give a characteristic dark brown or black color in the presence of a bismuth indicator.
  • the neomycin while it will inhibit bacterial growth will not inhibit the growth of other molds, such as peni-cillum, but such other mold would not give the characteristic color indicating the presence of Candida albicans.
  • Example 1 The following constitutes a diagnostic medium in accordance with the present invention for determining the presence of Candida albicans in vaginal infection.
  • This basic medium is made antibacterial by the addition thereto of neomycin sulfate.
  • a medium is made of the following composition:
  • Percent Yeast extract 0.1 Glycine 1.0 Dextrose 1.0 Bismuth sulfite indicator 0.8 Neomycin sulfate 0.0002 Agar 3.9
  • the above composition is moulded onto a wooden stick having a cotton tip at an end thereof.
  • the resulting swab is then placed in a sterile tube, and when ready to make the culture, it is removed and the smear made by rubbing the swab directly on the surface of the tissue to be tested.
  • the swab is then reinserted into the tube and incubated at 25 C. to 37 C. When C. albicans is present black colonies appear, while any other fungus will not give this type of growth. Bacteria are inhibited by both the neomycin sulfate and bismuth sulfite indicator.
  • Example 3 For detecting bacterial growth in urine:
  • An arrangement for making a culture of microorganisms from animal or human tissue by direct contact of the tissue with a culture medium comprising an elongated support contacting and carrying substantially only a mass of sterile solidified culture medium at an end of the support, and a sterile container removably housing said support carrying said mass of sterile solidified culture medium.
  • said elongated support is made of plastic and is provided at one end with a T-shaped projection and said sterile solidified culture medium is carried at said end on said T-shaped projection.
  • said elongated support is made of plastic and is provided at one end with an arrowhead-shaped projection and said sterile solidified culture medium is carried at said end on said arrowhead-shaped projection.
  • said solidified culture medium is formed of at least 3% by weight of agar.

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medical Informatics (AREA)
  • Surgery (AREA)
  • Molecular Biology (AREA)
  • Pathology (AREA)
  • Epidemiology (AREA)
  • Vascular Medicine (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
US404852A 1964-10-19 1964-10-19 Diagnostic swabs Expired - Lifetime US3368549A (en)

Priority Applications (5)

Application Number Priority Date Filing Date Title
US404852A US3368549A (en) 1964-10-19 1964-10-19 Diagnostic swabs
GB42175/65A GB1082459A (en) 1964-10-19 1965-10-05 Diagnostic swabs
DE6604278U DE6604278U (de) 1964-10-19 1965-10-18 Diagnostiziervorrichtung
DE19651492038 DE1492038A1 (de) 1964-10-19 1965-10-18 Diagnostiziervorrichtung
NL6513509A NL6513509A (xx) 1964-10-19 1965-10-19

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US404852A US3368549A (en) 1964-10-19 1964-10-19 Diagnostic swabs

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US3368549A true US3368549A (en) 1968-02-13

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US404852A Expired - Lifetime US3368549A (en) 1964-10-19 1964-10-19 Diagnostic swabs

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US (1) US3368549A (xx)
DE (2) DE6604278U (xx)
GB (1) GB1082459A (xx)
NL (1) NL6513509A (xx)

Cited By (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3450129A (en) * 1966-07-06 1969-06-17 Medical Supply Co Swabbing unit
US3626470A (en) * 1969-08-28 1971-12-07 Armour Pharma Diagnostic device for obtaining cytologic samples
US3630190A (en) * 1970-03-13 1971-12-28 Schmid Inc Julius Intrauterine probe
US3674007A (en) * 1970-06-04 1972-07-04 John H Freis Culture collecting apparatus
US3712296A (en) * 1970-12-08 1973-01-23 F Gradone Swab device for medical specimens
US3750646A (en) * 1971-12-16 1973-08-07 C Patterson Transport system for bacteria with provisions for carbogenophilic organisms
US3924607A (en) * 1973-02-05 1975-12-09 Louis Bucalo Device for testing for the presence of micro-organisms
US3934575A (en) * 1973-02-05 1976-01-27 Louis Bucalo Tampon device to test for micro-organisms
US3998211A (en) * 1974-08-23 1976-12-21 Louis Bucalo Structures for growing cultures within human and animal bodies
WO1986005205A1 (en) * 1985-03-04 1986-09-12 Regents Of The University Of Minnesota Method for the early diagnosis of bordetella diseases and kit therefor
US4633886A (en) * 1985-05-02 1987-01-06 Bucaro Jr Russell J Device for home detection of cervical and vaginal cancer
US4635488A (en) * 1984-12-03 1987-01-13 Schleicher & Schuell, Inc. Nonintrusive body fluid samplers and methods of using same
US4789639A (en) * 1987-01-02 1988-12-06 Becton, Dickinson And Company Liquid recovery device
US4803998A (en) * 1986-01-27 1989-02-14 Ncs Diagnostics, Inc. Swab retaining vial cap and method of use
US4838851A (en) * 1986-11-26 1989-06-13 Shabo Alan L Applicator and package therefor
US4953560A (en) * 1989-12-07 1990-09-04 Bernard Samuels Apparatus, method, and test kit for diagnosis of vaginal yeast infections
US5127899A (en) * 1989-04-18 1992-07-07 Schmerse Jr Roscoe E Swab
US5339828A (en) * 1993-01-25 1994-08-23 Keating Daniel J Apparatus and method for taking cultures endoscopically
US5404764A (en) * 1994-02-07 1995-04-11 Guest; Rodger L. Liquid sample container system
US5467780A (en) * 1993-05-04 1995-11-21 Nabai; Hossein Biopsy wound closure device and method
US5830186A (en) * 1995-04-06 1998-11-03 G. & P. Technologies, Inc. Method of dispensing medications by use of mucous membrane infusor
USD405175S (en) * 1998-04-09 1999-02-02 Stredic Iii Prince-Allen Absorbent swab
US6021681A (en) * 1997-06-27 2000-02-08 The United States Of America As Represented By The United States Department Of Energy Sampling device with a capped body and detachable handle
USD428225S (en) * 1997-09-19 2000-07-11 International Business Machines Corporation Cleaning apparatus for cleaning precision components
US6182666B1 (en) 1996-12-26 2001-02-06 Cryogen, Inc. Cryosurgical probe and method for uterine ablation
US6270494B1 (en) 1996-12-26 2001-08-07 Cryogen, Inc. Stretchable cryoprobe sheath
US20050010133A1 (en) * 2003-07-08 2005-01-13 Larry Pestes Specimen collection system
US20050070843A1 (en) * 2003-09-30 2005-03-31 Xanodyne Pharmacal, Inc. Central nervous system administration of medications by means of pelvic venous catheterization and reversal of Batson's Plexus
US20080057532A1 (en) * 2006-08-31 2008-03-06 Stephanie Martin Method for detecting Candida on skin
US20080118989A1 (en) * 1999-05-14 2008-05-22 Gen-Probe Incorporated Method for accessing the contents of a closed collection device
US20080300527A1 (en) * 2007-06-04 2008-12-04 Bivins Bruce R Handheld devices for manually cleaning body orifices
US20090048534A1 (en) * 2005-06-08 2009-02-19 Daniele Triva Device for the Withdrawal, collection and Transport of Biological Specimens
US20090111088A1 (en) * 2007-08-30 2009-04-30 Kimberly-Clark Worldwide, Inc. Rapid assessment of upper respiratory conditions
US7531319B2 (en) 2006-08-31 2009-05-12 Kimberly-Clark Worldwide, Inc. Array for rapid detection of a microorganism
US20090312722A1 (en) * 2005-08-04 2009-12-17 Laurent Philippe E Injection fluid leakage collection system and method
USD701600S1 (en) 2011-03-30 2014-03-25 Steven B. Kauffman Ear swab
CN105255718A (zh) * 2015-10-16 2016-01-20 广东海大集团股份有限公司 一种检验棉拭子及其制备方法和检验方法
USD1041005S1 (en) * 2022-01-17 2024-09-03 Rc Medical L.L.C. Surgical instrument cleaning assembly

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4618576A (en) * 1984-02-27 1986-10-21 Becton Dickinson And Company Diagnostic test for Streptococcus A
US5468236A (en) * 1993-06-09 1995-11-21 Kimberly-Clark Corporation Disposable absorbent product incorporating chemically reactive substance
DE10311981A1 (de) * 2003-03-12 2004-09-23 Oligene Gmbh Vorrichtung und Verfahren für den vivo-Zelltransfer

Citations (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1388960A (en) * 1920-04-22 1921-08-30 William F Lerch Swab
US1652108A (en) * 1925-05-02 1927-12-06 Forbis Hazel Tietjen Swab
US2490168A (en) * 1947-02-21 1949-12-06 Oscar A Strauss Sinus medication applicator
US2792331A (en) * 1953-03-26 1957-05-14 Helen A Boxell Culture medium for bacteria
US2844515A (en) * 1953-07-17 1958-07-22 Sobotka Harry Medium and method for the mass culture of microorganisms
US3037496A (en) * 1959-08-03 1962-06-05 Frederick J Melges Fertility testing apparatus
US3117569A (en) * 1959-05-21 1964-01-14 Aurthur H Griep Indicator instrument
US3163160A (en) * 1962-11-15 1964-12-29 Milton J Cohen Disposable swab and culture medium device
US3179108A (en) * 1963-02-15 1965-04-20 Johnson & Johnson Applicator
US3308039A (en) * 1966-02-15 1967-03-07 Allergan Pharma Disposable culturing device

Patent Citations (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1388960A (en) * 1920-04-22 1921-08-30 William F Lerch Swab
US1652108A (en) * 1925-05-02 1927-12-06 Forbis Hazel Tietjen Swab
US2490168A (en) * 1947-02-21 1949-12-06 Oscar A Strauss Sinus medication applicator
US2792331A (en) * 1953-03-26 1957-05-14 Helen A Boxell Culture medium for bacteria
US2844515A (en) * 1953-07-17 1958-07-22 Sobotka Harry Medium and method for the mass culture of microorganisms
US3117569A (en) * 1959-05-21 1964-01-14 Aurthur H Griep Indicator instrument
US3037496A (en) * 1959-08-03 1962-06-05 Frederick J Melges Fertility testing apparatus
US3163160A (en) * 1962-11-15 1964-12-29 Milton J Cohen Disposable swab and culture medium device
US3179108A (en) * 1963-02-15 1965-04-20 Johnson & Johnson Applicator
US3308039A (en) * 1966-02-15 1967-03-07 Allergan Pharma Disposable culturing device

Cited By (58)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3450129A (en) * 1966-07-06 1969-06-17 Medical Supply Co Swabbing unit
US3626470A (en) * 1969-08-28 1971-12-07 Armour Pharma Diagnostic device for obtaining cytologic samples
US3630190A (en) * 1970-03-13 1971-12-28 Schmid Inc Julius Intrauterine probe
US3674007A (en) * 1970-06-04 1972-07-04 John H Freis Culture collecting apparatus
US3712296A (en) * 1970-12-08 1973-01-23 F Gradone Swab device for medical specimens
US3750646A (en) * 1971-12-16 1973-08-07 C Patterson Transport system for bacteria with provisions for carbogenophilic organisms
US3924607A (en) * 1973-02-05 1975-12-09 Louis Bucalo Device for testing for the presence of micro-organisms
US3934575A (en) * 1973-02-05 1976-01-27 Louis Bucalo Tampon device to test for micro-organisms
US3998211A (en) * 1974-08-23 1976-12-21 Louis Bucalo Structures for growing cultures within human and animal bodies
US4635488A (en) * 1984-12-03 1987-01-13 Schleicher & Schuell, Inc. Nonintrusive body fluid samplers and methods of using same
US4652521A (en) * 1985-03-04 1987-03-24 Regents Of The University Of Minnesota Method for the early diagnosis of bordetella diseases and kit therefor
WO1986005205A1 (en) * 1985-03-04 1986-09-12 Regents Of The University Of Minnesota Method for the early diagnosis of bordetella diseases and kit therefor
US4633886A (en) * 1985-05-02 1987-01-06 Bucaro Jr Russell J Device for home detection of cervical and vaginal cancer
US4803998A (en) * 1986-01-27 1989-02-14 Ncs Diagnostics, Inc. Swab retaining vial cap and method of use
US4838851A (en) * 1986-11-26 1989-06-13 Shabo Alan L Applicator and package therefor
US4789639A (en) * 1987-01-02 1988-12-06 Becton, Dickinson And Company Liquid recovery device
US5127899A (en) * 1989-04-18 1992-07-07 Schmerse Jr Roscoe E Swab
US4953560A (en) * 1989-12-07 1990-09-04 Bernard Samuels Apparatus, method, and test kit for diagnosis of vaginal yeast infections
US5339828A (en) * 1993-01-25 1994-08-23 Keating Daniel J Apparatus and method for taking cultures endoscopically
US5467780A (en) * 1993-05-04 1995-11-21 Nabai; Hossein Biopsy wound closure device and method
US5404764A (en) * 1994-02-07 1995-04-11 Guest; Rodger L. Liquid sample container system
US5830186A (en) * 1995-04-06 1998-11-03 G. & P. Technologies, Inc. Method of dispensing medications by use of mucous membrane infusor
US5846216A (en) * 1995-04-06 1998-12-08 G & P Technologies, Inc. Mucous membrane infusor and method of use for dispensing medications
US6270494B1 (en) 1996-12-26 2001-08-07 Cryogen, Inc. Stretchable cryoprobe sheath
US6475212B2 (en) 1996-12-26 2002-11-05 Cryogen, Inc. Cryosurgical probe with sheath
US6182666B1 (en) 1996-12-26 2001-02-06 Cryogen, Inc. Cryosurgical probe and method for uterine ablation
US6193644B1 (en) 1996-12-26 2001-02-27 Cryogen, Inc. Cryosurgical probe with sheath
US6451012B2 (en) 1996-12-26 2002-09-17 Cryogen, Inc. Cryosurgical method for endometrial ablation
US6021681A (en) * 1997-06-27 2000-02-08 The United States Of America As Represented By The United States Department Of Energy Sampling device with a capped body and detachable handle
USD428225S (en) * 1997-09-19 2000-07-11 International Business Machines Corporation Cleaning apparatus for cleaning precision components
USD405175S (en) * 1998-04-09 1999-02-02 Stredic Iii Prince-Allen Absorbent swab
US7927549B2 (en) 1999-05-14 2011-04-19 Gen-Probe Incorporated Method for accessing the contents of a closed collection device with a modified pipette tip
US8535621B2 (en) * 1999-05-14 2013-09-17 Gen-Probe Incorporated Penetrable cap having rib structures
US8334145B2 (en) 1999-05-14 2012-12-18 Gen-Probe Incorporated Pierceable cap having spaced-apart grooves
US20080118989A1 (en) * 1999-05-14 2008-05-22 Gen-Probe Incorporated Method for accessing the contents of a closed collection device
US20080152545A1 (en) * 1999-05-14 2008-06-26 Gen-Probe Incorporated Assembly containing a specimen retrieval device
US8211710B2 (en) 1999-05-14 2012-07-03 Dickey Kathleen A Method for accessing the contents of a closed collection device
US20080245163A1 (en) * 1999-05-14 2008-10-09 Gen-Probe Incorporated Penetrable cap having rib structures
US20080274514A1 (en) * 1999-05-14 2008-11-06 Gen-Probe Incorporated Penetrable cap having spaced-apart grooves
US8038967B2 (en) 1999-05-14 2011-10-18 Gen-Probe Incorporated Method for accessing the contents of a closed vessel containing a specimen retrieval device
US20050010133A1 (en) * 2003-07-08 2005-01-13 Larry Pestes Specimen collection system
US20050070843A1 (en) * 2003-09-30 2005-03-31 Xanodyne Pharmacal, Inc. Central nervous system administration of medications by means of pelvic venous catheterization and reversal of Batson's Plexus
US20080058768A1 (en) * 2003-09-30 2008-03-06 Serene Medical, Inc. Central Nervous System Administration of Medications by Means of Pelvic Venous Catheterization and Reversal of Batson's Plexus
US7431717B2 (en) 2003-09-30 2008-10-07 Serene Medical, Inc. Central nervous system administration of medications by means of pelvic venous catheterization and reversal of Batson's Plexus
US20090048534A1 (en) * 2005-06-08 2009-02-19 Daniele Triva Device for the Withdrawal, collection and Transport of Biological Specimens
US20090312722A1 (en) * 2005-08-04 2009-12-17 Laurent Philippe E Injection fluid leakage collection system and method
AU2007290941B2 (en) * 2006-08-31 2012-08-09 Kimberly-Clark Worldwide, Inc. Method for detecting Candida on skin
US7763442B2 (en) * 2006-08-31 2010-07-27 Kimberly-Clark Worldwide, Inc. Method for detecting candida on skin
US20090221061A1 (en) * 2006-08-31 2009-09-03 Kimberly-Clark Worldwide, Inc. Array for Rapid Detection of a Microorganism
US20080057532A1 (en) * 2006-08-31 2008-03-06 Stephanie Martin Method for detecting Candida on skin
US8361742B2 (en) 2006-08-31 2013-01-29 Kimberly-Clark Worldwide, Inc. Method for detecting Candida on skin
US7531319B2 (en) 2006-08-31 2009-05-12 Kimberly-Clark Worldwide, Inc. Array for rapid detection of a microorganism
US8617874B2 (en) 2006-08-31 2013-12-31 Kimberly-Clark Worldwide, Inc. Array for rapid detection of a microorganism
US20080300527A1 (en) * 2007-06-04 2008-12-04 Bivins Bruce R Handheld devices for manually cleaning body orifices
US20090111088A1 (en) * 2007-08-30 2009-04-30 Kimberly-Clark Worldwide, Inc. Rapid assessment of upper respiratory conditions
USD701600S1 (en) 2011-03-30 2014-03-25 Steven B. Kauffman Ear swab
CN105255718A (zh) * 2015-10-16 2016-01-20 广东海大集团股份有限公司 一种检验棉拭子及其制备方法和检验方法
USD1041005S1 (en) * 2022-01-17 2024-09-03 Rc Medical L.L.C. Surgical instrument cleaning assembly

Also Published As

Publication number Publication date
DE1492038A1 (de) 1969-06-26
GB1082459A (en) 1967-09-06
DE6604278U (de) 1969-12-18
NL6513509A (xx) 1966-04-20

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Evans A simple method for the determination of bacterial sensitivity to sulphonamides by the use of blotting-paper disks
JPS632591B2 (xx)
Auger A New Method of Culturing Sputum on Solid Media Using Carbon Dioxide for the Isolation of Pneumococci