US2869544A - Injector - Google Patents

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US2869544A
US2869544A US693356A US69335657A US2869544A US 2869544 A US2869544 A US 2869544A US 693356 A US693356 A US 693356A US 69335657 A US69335657 A US 69335657A US 2869544 A US2869544 A US 2869544A
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Prior art keywords
barrel
injector
chamber
diluent
powder
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US693356A
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Karl A Ratcliff
William A Dorrance
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IOWA COOPERATIVE ASS
IOWA COOPERATIVE ASSOCIATION
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IOWA COOPERATIVE ASS
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61DVETERINARY INSTRUMENTS, IMPLEMENTS, TOOLS, OR METHODS
    • A61D1/00Surgical instruments for veterinary use
    • A61D1/02Trocars or cannulas for teats; Vaccination appliances
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M3/00Medical syringes, e.g. enemata; Irrigators
    • A61M3/005Medical syringes, e.g. enemata; Irrigators comprising means for injection of two or more media, e.g. by mixing
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M31/00Devices for introducing or retaining media, e.g. remedies, in cavities of the body
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/19Syringes having more than one chamber, e.g. including a manifold coupling two parallelly aligned syringes through separate channels to a common discharge assembly
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F31/00Mixers with shaking, oscillating, or vibrating mechanisms
    • B01F31/44Mixers with shaking, oscillating, or vibrating mechanisms with stirrers performing an oscillatory, vibratory or shaking movement
    • B01F31/441Mixers with shaking, oscillating, or vibrating mechanisms with stirrers performing an oscillatory, vibratory or shaking movement performing a rectilinear reciprocating movement
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F33/00Other mixers; Mixing plants; Combinations of mixers
    • B01F33/50Movable or transportable mixing devices or plants
    • B01F33/501Movable mixing devices, i.e. readily shifted or displaced from one place to another, e.g. portable during use
    • B01F33/5011Movable mixing devices, i.e. readily shifted or displaced from one place to another, e.g. portable during use portable during use, e.g. hand-held
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F33/00Other mixers; Mixing plants; Combinations of mixers
    • B01F33/50Movable or transportable mixing devices or plants
    • B01F33/501Movable mixing devices, i.e. readily shifted or displaced from one place to another, e.g. portable during use
    • B01F33/5011Movable mixing devices, i.e. readily shifted or displaced from one place to another, e.g. portable during use portable during use, e.g. hand-held
    • B01F33/50112Movable mixing devices, i.e. readily shifted or displaced from one place to another, e.g. portable during use portable during use, e.g. hand-held of the syringe or cartridge type
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F35/00Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F35/71Feed mechanisms
    • B01F35/713Feed mechanisms comprising breaking packages or parts thereof, e.g. piercing or opening sealing elements between compartments or cartridges
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F35/00Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F35/71Feed mechanisms
    • B01F35/713Feed mechanisms comprising breaking packages or parts thereof, e.g. piercing or opening sealing elements between compartments or cartridges
    • B01F35/7139Removing separation walls, plugs which close off the different compartments, e.g. by rotation or axially sliding
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F35/00Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F35/71Feed mechanisms
    • B01F35/716Feed mechanisms characterised by the relative arrangement of the containers for feeding or mixing the components
    • B01F35/7161Feed mechanisms characterised by the relative arrangement of the containers for feeding or mixing the components the containers being connected coaxially before contacting the contents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/315Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31596Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms comprising means for injection of two or more media, e.g. by mixing
    • A61M2005/31598Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms comprising means for injection of two or more media, e.g. by mixing having multiple telescopically sliding coaxial pistons encompassing volumes for components to be mixed
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/315Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31596Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms comprising means for injection of two or more media, e.g. by mixing
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F35/00Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F35/30Driving arrangements; Transmissions; Couplings; Brakes
    • B01F35/32Driving arrangements
    • B01F35/32005Type of drive
    • B01F35/3202Hand driven

Definitions

  • a prepared powder compound is packaged ready for use in a syringe or injector type apparatus.
  • Such compound not being stable in a water solution is suspended in an oil solution to properly maintain it for use over a reasonable period of storage or shelf life.
  • an oil solution has certain undesirable effects relative to the cows milk which are not here material but which is mentioned to better understand the Vnature and purpose of this invention.
  • an injector for medicaments which includes means to store a medicinal compound in powder form, a reservoir for holding a suitable diluent or solvent for the powder, means to mix the powder-,and diluent when desired and means forf ejecting the same.
  • Another object contemplated by this invention is the provision of an improved injector of the above class that is compactly formed, easy to use, and sufficiently economical in construction so that it can be discarded after being used.
  • Fig. 1 is a side elevational view showing this injector ready for use
  • Fig. 2 is an end view thereof taken from the line 2--2 of Fig. l,
  • Fig. 3 is a longitudinal section view taken on the line 3-3 of Fig. 2.
  • Fig. 4 is a side elevational view of this injector showing the same manipulated for causing the admixture of powder and diluent as indicated by the part of this View in section, and,
  • Fig. 5 is a side elevational view partly in section showing the inal position of the plunger units after the solution has been ejected.
  • this injector includes a first cylindrical barrel 12 and asecond cylindrical barrel 14 concentrically smaller than barrel'12 and slidably disposed therein.
  • the outlet end 16 of barrel 12 is tapered to a funnel shape and terminates in a projecting needlelike member 18 which communicates with the interior chamber 20 of barrel 12 by bore 22.
  • the other end of 2,869,544 ⁇ Patented Jan. 20, 1959 2 barrel 12 is formed withthe integral ange 24 projecting perpendicularly therefrom in at least two opposite directions (Fig. 2) to provide a suitable finger gripping means as is well known.
  • a removable cap 26 is provided for needle 18.
  • Barrel 14 is formed generally similar to barrel 12 having the funnel like outlet end 28 in which there is the central outlet opening 30 (Fig.
  • a suitable flexible gasket or washer like cap 34 shaped to conform to end 28 of barrel 14 is mounted on such end and includes an opening which registers with opening 30, the purpose of such gasket being to provide a sealing contact between end portion 28 of barrel 14 andthe inner surface 5 of barrel 12.
  • a resilient cap of rubber or the like 36 On the other end of barrel 14 is a resilient cap of rubber or the like 36 having a central opening 38.
  • a Longitudinally movable within barrel 14 is the concentrically disposed plunger rod 40 which at one end extends through opening 3S in cap 36 to terminate in a concentrically enlarged tapered seat 42 attached to knob 44, and on the other end terminates in a tip end 46 which includes the annular washer like flange 48 spaced rearwardly from the free end thereof.
  • Tip 46 is designed to penetrate opening 30 in gasket 34 at times with washer 48 seating against the inner side of such opening in sealing engagement therewith, and on the other end of rod 40, member 42 will seat in opening 33 of cap 36.
  • This injector as disclosed is used in the following manner. ,itV is packaged prepared for use and in such form will be ⁇ substantially as shown in Fig. 3 where barrel 14 is partially inserted into barrel 12 with rod 40 in position to seal openings 30 and 38 as described above.
  • Chamber 20 is provided fwith a supply of the medicament to beused in powder powder 50.
  • plunger rod 40 is partially withdrawn from barrel 14 by means of knob 44 sufficiently to unseal the openings 30 and 38 as shown in Fig. 4 and then a slight withdrawal of barrel 14 relative to barrel 12 will produce suicient vacuum within barrel 12 to cause the transfer of diluent 50 from chamber 32 through opening 30 into chamber 20 and such transfer movement is aided by the fact that opening 38 is opened to the atmosphere since rod 40 is' of less diameter than such opening.
  • Rod 40 is then pushed into barrel 14 to close openings 30 and 38 as in its initial position shown in Fig. 3.
  • the transfer movement of diluent 52 as described will generally result in a satisfactory admixture of powder 50 therewith but, if desired, the injector can be manually shaken for further mixing.
  • tip A46 reinserted in opening 30 to seal the same, barrel 14 with cap 34 becomes in effect a plunger and with cap 26 removed, the admixed solution in chamber 20 is discharged through needle 18 by pushing barrel 14 into barrel 12 as seen in Fig. 5.
  • injecter device for administering. a medicament. omprisinglirst and ⁇ second cylindrical barrels in telescopic relationship, said second .barrel being movable longitudinally within the irst, said iirst barrel provided with an outlet end, said second barrel provided with open ings on respective opposite ends with one of said openings being 'an outletdisposed within said first barrel, closure means in said second barrel for selectively simultaneously opening and closing said openings therein, each bfrel dsnins a .Separate chamber with the chamber in Said first barrel designed to hold a Supply Qf @lv pQwdei medicament and the chamber in Said.
  • AScnd barrel desi ed to hold a diluent
  • the openingA of the openings in said second barrel causing said diluent to become admixed with said powder
  • the closure of said openings in sai/d secrond barrel imparting to said second barrel the characteristics of a plunger which when forced into said lirst barrel ejects the admixed solution from the outlet therein- V2.
  • An injector device for administering a medicament comprising rst and second cylindrical barrels in telescopicY relationship, said second barrel being movable longitudinally within the first, said first barrel provided with an outlet end, said second barrel provided with open ings o n respective opposite ends with one of said openings being'an outlet disposed within said iirst barrel, a plunger rod ⁇ longitudinally movable in said second barrel, respective ymeans on said plunger rod susceptible of sealing engagement with the respective openings in said second barrel whereby movement of said rod will selectively simultaneously open and close said openings, each barrel defining a separate chamber with the chamber in said first ⁇ barrel designed to hold a supply of a powder medicament and the'chamber in said second barrel designed' to yhold a diluent, the opening of the( openings in said second.
  • a medicament injector comprising first and second barrels in telescopic relationship, said first barrel having an outlet port, a removable closure for said outlet port, said second barrel having an outlet port disposed within said rst barrel, closure means for the outlet port on said second barrel, said second b arrel serving as a closure means for one end of said rst barrel to provide a charnber therein, said second barrel deiining a second chamber, said closure means on the outlet port of said second barrel a removable to aord communication between said chamhers, and the closure of the outlet port in said second barrel giving said barrel the characteristics of a plunger movable to displace any contents in said first barrel by ejecting the same from the outlet therein.
  • a medicament injector comprising first and second barrels in telescopic relationship, said first barrel having an outlet port, a removable closure for said outlet port, said second barrel having an outlet port disposed within said iirst barrel, a rod member in said second barrel IflOVable into and out of sealing engagement with the outlet port therein, said second barrel serving as a closure means for one end of said irst barrel to provide a chambertherein,v said second barrel defining a second chamber, the chamber in said iirst barrel designed to hold a supply of a powder medicament, the chamber in said second barrel designed to hold a supply of a diluent, movement of said rod nlerrlberA out of engagement with the outlet port of said second barrel and a partial Withdrawal of said second barrel from thev iirst barrel creating an air pressure differential causing the transfer of diluent to the chamber of said iirst barrel for admixture with the powder therein,

Description

United-States Patent() INJECTOR Karl A. Ratclilf and William A. Dorrance, Des Moines, Iowa, assgnors to Iowa Cooperative Association, doing business as Diamond Laboratories, Des Moines, Iowa, a corporation of Iowa Application October 30, 1957, Serial No. 693,356
4 Claims. (Cl. 12S-220) Our invention relates to improvements in injectors used in the administration of `medicaments and while it was particularly designed for treatment of mastitis in cows requiring injection into the udder, its use is not limited thereto as will later appear. This application will disclose an improved structure over the injector described in our co-pending application tiled August 23, 1957, Serial No. 679,869.
As presently practiced in the treatment for mastitis in cows a prepared powder compound is packaged ready for use in a syringe or injector type apparatus. Such compound not being stable in a water solution is suspended in an oil solution to properly maintain it for use over a reasonable period of storage or shelf life. Experience has demonstrated that the use of an oil solution has certain undesirable effects relative to the cows milk which are not here material but which is mentioned to better understand the Vnature and purpose of this invention.
Having made the above observation over a long period of time it is one of the important objects of this invention to provide an injector for medicaments which includes means to store a medicinal compound in powder form, a reservoir for holding a suitable diluent or solvent for the powder, means to mix the powder-,and diluent when desired and means forf ejecting the same.
Another object contemplated by this invention is the provision of an improved injector of the above class that is compactly formed, easy to use, and sufficiently economical in construction so that it can be discarded after being used.
Other objects and advantages of this invention reside in the details of construction and correlation of `the various parts and will be apparent as the description proceeds This invention consists'of novel parts and combination of parts to be hereinafter described whereby the objects set forth are attained, as pointed out in the claims, and illustrated in the accompanying drawings, in which:
Fig. 1 is a side elevational view showing this injector ready for use,
Fig. 2 is an end view thereof taken from the line 2--2 of Fig. l,
' Fig. 3 is a longitudinal section view taken on the line 3-3 of Fig. 2.
Fig. 4 is a side elevational view of this injector showing the same manipulated for causing the admixture of powder and diluent as indicated by the part of this View in section, and,
Fig. 5 is a side elevational view partly in section showing the inal position of the plunger units after the solution has been ejected.
Referring to the drawings this injector includes a first cylindrical barrel 12 and asecond cylindrical barrel 14 concentrically smaller than barrel'12 and slidably disposed therein. The outlet end 16 of barrel 12 is tapered to a funnel shape and terminates in a projecting needlelike member 18 which communicates with the interior chamber 20 of barrel 12 by bore 22. The other end of 2,869,544 `Patented Jan. 20, 1959 2 barrel 12 is formed withthe integral ange 24 projecting perpendicularly therefrom in at least two opposite directions (Fig. 2) to provide a suitable finger gripping means as is well known. A removable cap 26 is provided for needle 18. Barrel 14 is formed generally similar to barrel 12 having the funnel like outlet end 28 in which there is the central outlet opening 30 (Fig. 4) communicating with the interior chamber 32 of barrel 14. A suitable flexible gasket or washer like cap 34 shaped to conform to end 28 of barrel 14 is mounted on such end and includes an opening which registers with opening 30, the purpose of such gasket being to provide a sealing contact between end portion 28 of barrel 14 andthe inner surface 5 of barrel 12. On the other end of barrel 14 is a resilient cap of rubber or the like 36 having a central opening 38. A Longitudinally movable within barrel 14 is the concentrically disposed plunger rod 40 which at one end extends through opening 3S in cap 36 to terminate in a concentrically enlarged tapered seat 42 attached to knob 44, and on the other end terminates in a tip end 46 which includes the annular washer like flange 48 spaced rearwardly from the free end thereof. Tip 46 is designed to penetrate opening 30 in gasket 34 at times with washer 48 seating against the inner side of such opening in sealing engagement therewith, and on the other end of rod 40, member 42 will seat in opening 33 of cap 36. This injector as disclosed is used in the following manner. ,itV is packaged prepared for use and in such form will be `substantially as shown in Fig. 3 where barrel 14 is partially inserted into barrel 12 with rod 40 in position to seal openings 30 and 38 as described above. Cap 26 ris on needle 18 and thus chambers 20 and 32 in barrels 12 and 14 respectively are each a closed chamberrwith no communication therebetween. Chamber 20 is provided fwith a supply of the medicament to beused in powder powder 50. .For our particular use intreating mastitis in cows we haveused an aqueous diluent for the reasons above mentioned, but it will be understood that the particular use for which we have designed this injector is merely illustrative and accordingly the diluent to be used may be of any type suitable to the particular medicament employed.
To mix the elements 50 and 52 for use, plunger rod 40 is partially withdrawn from barrel 14 by means of knob 44 sufficiently to unseal the openings 30 and 38 as shown in Fig. 4 and then a slight withdrawal of barrel 14 relative to barrel 12 will produce suicient vacuum within barrel 12 to cause the transfer of diluent 50 from chamber 32 through opening 30 into chamber 20 and such transfer movement is aided by the fact that opening 38 is opened to the atmosphere since rod 40 is' of less diameter than such opening. Rod 40 is then pushed into barrel 14 to close openings 30 and 38 as in its initial position shown in Fig. 3. The transfer movement of diluent 52 as described will generally result in a satisfactory admixture of powder 50 therewith but, if desired, the injector can be manually shaken for further mixing. With tip A46 reinserted in opening 30 to seal the same, barrel 14 with cap 34 becomes in effect a plunger and with cap 26 removed, the admixed solution in chamber 20 is discharged through needle 18 by pushing barrel 14 into barrel 12 as seen in Fig. 5.
It will be understood that the phraseology employed herein is for the purpose of description and not for limitation and that modifications and changes in the construcor mechanical equivalents which may be reasonably ineluded within their scope.
We claim:
L. All, injecter device for administering. a medicament. omprisinglirst and `second cylindrical barrels in telescopic relationship, said second .barrel being movable longitudinally within the irst, said iirst barrel provided with an outlet end, said second barrel provided with open ings on respective opposite ends with one of said openings being 'an outletdisposed within said first barrel, closure means in said second barrel for selectively simultaneously opening and closing said openings therein, each bfrel dsnins a .Separate chamber with the chamber in Said first barrel designed to hold a Supply Qf @lv pQwdei medicament and the chamber in Said. AScnd barrel desi ed to hold a diluent, the openingA of the openings in said second barrel causing said diluent to become admixed with said powder and the closure of said openings in sai/d secrond barrel imparting to said second barrel the characteristics of a plunger which when forced into said lirst barrel ejects the admixed solution from the outlet therein- V2. An injector device for administering a medicament, comprising rst and second cylindrical barrels in telescopicY relationship, said second barrel being movable longitudinally within the first, said first barrel provided with an outlet end, said second barrel provided with open ings o n respective opposite ends with one of said openings being'an outlet disposed within said iirst barrel, a plunger rod` longitudinally movable in said second barrel, respective ymeans on said plunger rod susceptible of sealing engagement with the respective openings in said second barrel whereby movement of said rod will selectively simultaneously open and close said openings, each barrel defining a separate chamber with the chamber in said first` barrel designed to hold a supply of a powder medicament and the'chamber in said second barrel designed' to yhold a diluent, the opening of the( openings in said second. barrel causing said diluent to become ad- 3. A medicament injector comprising first and second barrels in telescopic relationship, said first barrel having an outlet port, a removable closure for said outlet port, said second barrel having an outlet port disposed within said rst barrel, closure means for the outlet port on said second barrel, said second b arrel serving as a closure means for one end of said rst barrel to provide a charnber therein, said second barrel deiining a second chamber, said closure means on the outlet port of said second barrel a removable to aord communication between said chamhers, and the closure of the outlet port in said second barrel giving said barrel the characteristics of a plunger movable to displace any contents in said first barrel by ejecting the same from the outlet therein.
4. A medicament injector comprising first and second barrels in telescopic relationship, said first barrel having an outlet port, a removable closure for said outlet port, said second barrel having an outlet port disposed within said iirst barrel, a rod member in said second barrel IflOVable into and out of sealing engagement with the outlet port therein, said second barrel serving as a closure means for one end of said irst barrel to provide a chambertherein,v said second barrel defining a second chamber, the chamber in said iirst barrel designed to hold a supply of a powder medicament, the chamber in said second barrel designed to hold a supply of a diluent, movement of said rod nlerrlberA out of engagement with the outlet port of said second barrel and a partial Withdrawal of said second barrel from thev iirst barrel creating an air pressure differential causing the transfer of diluent to the chamber of said iirst barrel for admixture with the powder therein,
and the closure of the outlet port in said second barrel givmixed withsaid powder, and the closure of said openings in said second barrel imparting to said second barrel the characteristics of a plunger which when forced into said iirst barrel ejects the admixed solution from the outlet therein.
ing said barrel the characteristics of a plunger movable to displace the admixed solution in said first barrel by ejecting the same from the outlet therein.
Referencesr Cited in the le of this patent UNITED STATES PATENTS4 743,743 McCulloch u Nov. 10, 1903 1,563,627 HeinV Dec. 1, 1925 2,490,552 Smith Dec. 6, 1 949 2,684,068 Orens ---a July 20, 1954
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Cited By (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3052239A (en) * 1959-01-29 1962-09-04 Silver Disposable hypodermic syringe
US3584626A (en) * 1967-11-22 1971-06-15 Lars Georg Johansson Hypodermic syringe
US3678930A (en) * 1971-01-19 1972-07-25 Boris Schwartz Intermixing syringe
US3685514A (en) * 1969-09-23 1972-08-22 Paul E Cheney Two compartment syringe
US3707146A (en) * 1967-03-07 1972-12-26 Prod Res & Chem Corp Means to inject a plastic into a cavity to produce a replica thereof
WO1984001291A1 (en) * 1982-09-27 1984-04-12 Silver Ind Two compartment mixing syringe seal
EP0182005A2 (en) * 1984-11-14 1986-05-28 Bramlage GmbH Ointment applicator
US5224937A (en) * 1991-06-21 1993-07-06 Npbi Nederlands Produktielaboratorium Voor Bloedtransfusieapparatuur En Infusievloeistoffen B.V. Closed syringe-filling system
US20060079834A1 (en) * 2004-10-13 2006-04-13 Hyprotek, Inc. Syringe devices and methods for mixing and administering medication
US20070167910A1 (en) * 2005-11-09 2007-07-19 Hyprotek, Inc. Syringe Devices, Components of Syringe Devices, and Methods of Forming Components and Syringe Devices
EP2286906A3 (en) * 2005-07-18 2011-03-30 Plant Bioscience Limited (PBL) Apparatus, system and method for simulating digestion of a foodstuff
US20110159779A1 (en) * 2009-12-24 2011-06-30 Willy Chen Water shooting toy with high capacity
US8002737B2 (en) 2007-10-04 2011-08-23 Hyprotek, Inc. Mixing/administration syringe devices, protective packaging and methods of protecting syringe handlers
US20120211378A1 (en) * 2010-11-17 2012-08-23 La Prairie, Inc. Two compartment container
US9180249B2 (en) 2004-02-02 2015-11-10 Bimeda Research & Development Limited Method and device
US9522097B2 (en) 2007-10-04 2016-12-20 Hyprotek, Inc. Mixing/administration syringe devices, protective packaging and methods of protecting syringe handlers
US9850058B2 (en) 2015-09-11 2017-12-26 New Product Development Concepts Llc Telescoping syringe with one-way valve
US20180086544A1 (en) * 2015-09-11 2018-03-29 New Product Development Concepts Llc Telescoping Syringe with One-Way Valve

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US3707146A (en) * 1967-03-07 1972-12-26 Prod Res & Chem Corp Means to inject a plastic into a cavity to produce a replica thereof
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US3678930A (en) * 1971-01-19 1972-07-25 Boris Schwartz Intermixing syringe
WO1984001291A1 (en) * 1982-09-27 1984-04-12 Silver Ind Two compartment mixing syringe seal
US4464174A (en) * 1982-09-27 1984-08-07 Silver Industries, Inc. Two compartment mixing syringe seal
EP0182005A2 (en) * 1984-11-14 1986-05-28 Bramlage GmbH Ointment applicator
EP0182005A3 (en) * 1984-11-14 1987-05-13 Bramlage Gmbh Ointment applicator
US5224937A (en) * 1991-06-21 1993-07-06 Npbi Nederlands Produktielaboratorium Voor Bloedtransfusieapparatuur En Infusievloeistoffen B.V. Closed syringe-filling system
US9180249B2 (en) 2004-02-02 2015-11-10 Bimeda Research & Development Limited Method and device
US7731678B2 (en) * 2004-10-13 2010-06-08 Hyprotek, Inc. Syringe devices and methods for mixing and administering medication
US7985211B2 (en) 2004-10-13 2011-07-26 Hyprotek, Inc. Syringe devices and methods for mixing and administering medication
US20070255203A1 (en) * 2004-10-13 2007-11-01 Hyprotek, Inc. Syringe Devices and Methods for Mixing and Administering Medication
US20070255226A1 (en) * 2004-10-13 2007-11-01 Hyprotek, Inc. Syringe Devices and Methods for Mixing and Administering Medication
US20070260176A1 (en) * 2004-10-13 2007-11-08 Hyprotek, Inc. Syringe Devices and Methods for Mixing and Administering Medication
US20070265578A1 (en) * 2004-10-13 2007-11-15 Hyprotek, Inc. Syringe Devices and Methods for Mixing and Administering Medication
US20070276322A1 (en) * 2004-10-13 2007-11-29 Hyprotek, Inc. Syringe Devices and Methods for Mixing and Administering Medication
US7635344B2 (en) 2004-10-13 2009-12-22 Hyprotek, Inc. Syringe devices and methods for mixing and administering medication
US7731679B2 (en) 2004-10-13 2010-06-08 Hyprotek, Inc. Syringe devices and methods for mixing and administering medication
US11376195B2 (en) 2004-10-13 2022-07-05 Hyprotek, Inc. Syringe devices and methods for mixing and administering medication
US7749189B2 (en) 2004-10-13 2010-07-06 Hyprotek, Inc. Syringe devices and methods for mixing and administering medication
US7753891B2 (en) 2004-10-13 2010-07-13 Hyprotek, Inc. Syringe devices and methods for mixing and administering medication
US7776011B2 (en) 2004-10-13 2010-08-17 Hyprotek, Inc. Syringe devices and methods for mixing and administering medication
US9861555B2 (en) 2004-10-13 2018-01-09 Hyprotek, Inc. Syringe devices and methods for mixing and administering medication
US20060079834A1 (en) * 2004-10-13 2006-04-13 Hyprotek, Inc. Syringe devices and methods for mixing and administering medication
US20070249996A1 (en) * 2004-10-13 2007-10-25 Hyprotek, Inc. Syringe Devices and Methods for Mixing and Administering Medication
US8231567B2 (en) 2004-10-13 2012-07-31 Hyprotek, Inc. Syringe devices and methods for mixing and administering medication
EP2286906A3 (en) * 2005-07-18 2011-03-30 Plant Bioscience Limited (PBL) Apparatus, system and method for simulating digestion of a foodstuff
US8137307B2 (en) 2005-11-09 2012-03-20 Hyprotek, Inc. Syringe devices, components of syringe devices, and methods of forming components and syringe devices
US20070167910A1 (en) * 2005-11-09 2007-07-19 Hyprotek, Inc. Syringe Devices, Components of Syringe Devices, and Methods of Forming Components and Syringe Devices
US10485930B2 (en) 2005-11-09 2019-11-26 Hyprotek, Inc. Syringe devices, components of syringe devices, and methods of forming components and syringe devices
US8608686B2 (en) 2005-11-09 2013-12-17 Hyprotek, Inc. Syringe devices, components of syringe devices, and methods of forming components and syringe devices
US9522097B2 (en) 2007-10-04 2016-12-20 Hyprotek, Inc. Mixing/administration syringe devices, protective packaging and methods of protecting syringe handlers
US8512278B2 (en) 2007-10-04 2013-08-20 Hyprotek, Inc. Mixing/administration syringe devices, protective packaging and methods of protecting syringe handlers
US10524983B2 (en) 2007-10-04 2020-01-07 Hyprotek, Inc. Mixing/administration syringe devices, protective packaging and methods of protecting syringe handlers
US8002737B2 (en) 2007-10-04 2011-08-23 Hyprotek, Inc. Mixing/administration syringe devices, protective packaging and methods of protecting syringe handlers
US20110159779A1 (en) * 2009-12-24 2011-06-30 Willy Chen Water shooting toy with high capacity
US20120211378A1 (en) * 2010-11-17 2012-08-23 La Prairie, Inc. Two compartment container
US9850058B2 (en) 2015-09-11 2017-12-26 New Product Development Concepts Llc Telescoping syringe with one-way valve
US20180086544A1 (en) * 2015-09-11 2018-03-29 New Product Development Concepts Llc Telescoping Syringe with One-Way Valve
US10450124B2 (en) * 2015-09-11 2019-10-22 New Product Development Concepts Llc Telescoping syringe with one-way valve

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