US2672865A - Inhaler for medicinal substances - Google Patents

Inhaler for medicinal substances Download PDF

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Publication number
US2672865A
US2672865A US223184A US22318451A US2672865A US 2672865 A US2672865 A US 2672865A US 223184 A US223184 A US 223184A US 22318451 A US22318451 A US 22318451A US 2672865 A US2672865 A US 2672865A
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air
outlet
opening
powder
inhaler
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US223184A
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Harry G Willis
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/08—Inhaling devices inserted into the nose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0001—Details of inhalators; Constructional features thereof
    • A61M15/0021—Mouthpieces therefor
    • A61M15/0025—Mouthpieces therefor with caps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2206/00—Characteristics of a physical parameter; associated device therefor
    • A61M2206/10—Flow characteristics
    • A61M2206/16—Rotating swirling helical flow, e.g. by tangential inflows

Definitions

  • This invention relates" to; anA inhaler for medicinal substances.
  • the device is preferably provided with a sealing cap which may conveniently be of mushroom shape having a central plug which passes down and through the outlet so that it will be sealed when the plug is in use but the plug will serve to clear the outlet as it is removed, the outwardly extending portions lof the cap fitting over the projection through which the outlet is formed and having their lower periphery in contact with the air inlet or inlets through which the ne jets of air are drawn when the device is in use.
  • a sealing cap which may conveniently be of mushroom shape having a central plug which passes down and through the outlet so that it will be sealed when the plug is in use but the plug will serve to clear the outlet as it is removed, the outwardly extending portions lof the cap fitting over the projection through which the outlet is formed and having their lower periphery in contact with the air inlet or inlets through which the ne jets of air are drawn when the device is in use.
  • This unit will be found to be of simple construction and highly hygienic for the reason that the cap normally protects the portion placed into contact with the nostril or the mouth while at the same time loss of the content or contamination of same will be prevented by the seal which the plug effects both of the outlet and the ne jet openings.
  • Fig. '1 is a side elevation of the invention
  • Fig. 2 is a central longitudinal section
  • Fig. 3 is a view corresponding to Fig. 2 but showing the cap removed from the body
  • Fig. 4 is a central longitudinal section of a modified form of body
  • Fig. 5 is a longitudinal section of a still further modification.
  • The'body- Iz has ahollow Tin, which the powder toV be; inhaled isl disposed,- thebody being closed atv itsY lower end bya plug 3 and-having an; extensionY 4" curved inwardly to terminatei'nan outlet 5 through which, the inhaling takesplace.
  • Fitting ⁇ over the bod-y- I is' a capA 6 the lower endi off which;A engages aA port-ion 'lonthe bod-yy; the portion 'l-Y havingj a circumferentialf ridge- 8 which co-operateswitlrraf depressionin then cap 6 to elect a spring lock of' thecap 6- to the body Ii
  • the cap 6 has in-it a depending plug l0 which fitslinto-.theout-let 5'; at the'top of 'the-bodyv IA to seal Vthis out-let asshown'y more ⁇ particularly ⁇ in Fig. 2; f
  • An air inlet opening IJI substantially smaller than the outlet 5 and having a diameter no larger than one-quarter the diameter of the outlet, is formed through the portion 'I of the body I and is arranged to direct air downwardly into the powder space of the body so that when suction is applied through the outlet 5 the air flowing in through the air inlet opening II will disturb the powder either by direct contact or by reflex currents of air set up in the container to cause the powder to be lifted with ⁇ an upward flow of air taking place within the bondy I.
  • a further air inlet opening I4 is formed through the portion 1 of the body I, this air inlet opening, however, being arranged as an additional air bleed to permit a greater quantity of air to be drawn through the outlet 5 in the extension 4 of the body I.
  • the opening I I projecting a stream of air downwardly to disturb the powder and render at least some of it air-borne while the opening I4 admits additional air so that the ratio of air to powder being drawn through the outlet 5 gives more air for a measured quantity of powder and thus allo-ws the powder to be carried deep into the lungs or further back into the throat if such is desired.
  • the small opening I I only is used it will be appreciated that the amount of air flowing through the outlet 5 will be correspondingly small and the powder will settle in the nostrils or mouth more readily than is the case where a relatively large volume of air is being inhaled.
  • the body l kis provided with a shoulder I5 between which and the shoulder I6 of the body is disposed a rotatable sleeve I'I, the sleeve having an opening I8 which may register with the opening II in the body or may be brought into partial register only if such is desired, this then permitting the size of the opening II to be adjusted by appropriately orientating the sleeve I'I.
  • the cap 6 In use the cap 6 is simply removed from the body I and the outlet 5 placed into communication with the mouth or nostril whereupon when suction is applied the powder from the hollow 2 will be drawn up with the air depending in Volume on the size of the opening II and whether or not the additional opening I4 is used.
  • the cap When inhaling is completed the cap is simply replaced until such time as a further supply of the inhalant is required, the cap tting over the portion 1 of the body in the case of Figs. 1 to 4 or over the sleeve I 'I in the case of Fig. 5 to seal the air openings into the body so that when the cap is in position it closes the outlet 5 and at the same time the air inlet openings I I and I4 if used so that a hygienic and aseptic seal is formed for the container.
  • the unit can be formed of plastic or any other suitable material and it will be appreciated that the openings may be duplicated if desired an may be arranged tangentially.
  • An inhaler for medicinal inhalants comprising a hollow body for holding a medicinal inhalant and having an axial extension tapering to an unobstructed voutlet opening arranged axially at its end, and intermediate its ends said body having at least one straight air inlet opening extending oblquely through the wall of said body which has a diameter no greater than onequarter the diameter of said outlet opening and arranged to admit air into said hollow body in a direction away from said outlet opening when suction is applied to the latter, a cap to engage said body intermediate the ends oi' the latter and fit over said extension for sealing said inlet opening, and a stopper projecting axially within said cap to extend through and seal said outlet opening.
  • An inhaler according to claim 1 including an apertured sleeve movable on said body for selective registration with said air inlet opening to vary the effective area of the latter.

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pulmonology (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Otolaryngology (AREA)
  • Medicinal Preparation (AREA)
  • Respiratory Apparatuses And Protective Means (AREA)

Description

March 23, 1954 H, Q W|| 15 2,672,865
INHALER FOR MEDICINAL SUBSTANCES Filed April 27, 1951 F1a l 1711i Z IYl/ENTOI@ Patented Mar. 23, 1954 Hariri@ .Willis, Blackwood, -.Southuullst.lalia,
Australiar i AmiczttibnAprliZfl, 1951, Serial-Noz 223,184l
Gleim nifioritsf,,application-Australia May 19, 19.5.0k
This invention relates" to; anA inhaler for medicinal substances.,
`W'heninhaling" medicina-1r substances" either through the-nose orthe mouth it isdesirableito effect a very'nedischarge of"-`themateriaibeing inhaled.-
Where the. material vis a substancev Such as powdered penicillin certain diinculties present themselves [the r chief: off `which is y the inability withinhalers as constructedheretofore oi"4 maintainingsimplicity of constructionlwhile` achieving aneldischarge of the powder.
iii'ccording to this invention. the. inhalercomprisesa bodyprovidedat oneeendiwith ari-.extension having anou'tlet at its lend which can be engaged on a nostril or placed against or into the mouth, air inlet means being located through another part of the container and so arranged that when suction is applied to the outlet the reduction of pressure within the container will cause air to ow into same to cause small quantitles of the powder to be lifted in dust form and thus placed into a condition where they can be readily inhaled through the outlet.
The device is preferably provided with a sealing cap which may conveniently be of mushroom shape having a central plug which passes down and through the outlet so that it will be sealed when the plug is in use but the plug will serve to clear the outlet as it is removed, the outwardly extending portions lof the cap fitting over the projection through which the outlet is formed and having their lower periphery in contact with the air inlet or inlets through which the ne jets of air are drawn when the device is in use.
This unit will be found to be of simple construction and highly hygienic for the reason that the cap normally protects the portion placed into contact with the nostril or the mouth while at the same time loss of the content or contamination of same will be prevented by the seal which the plug effects both of the outlet and the ne jet openings.
In order, however, that the invention may be more clearly understood it will now be described with reference to the accompanying drawings in which:
Fig. '1 is a side elevation of the invention,
Fig. 2 is a central longitudinal section,
Fig. 3 is a view corresponding to Fig. 2 but showing the cap removed from the body,
Fig. 4 is a central longitudinal section of a modified form of body, and
Fig. 5 is a longitudinal section of a still further modification.
The'body- Izhas ahollow Tin, which the powder toV be; inhaled isl disposed,- thebody being closed atv itsY lower end bya plug 3 and-having an; extensionY 4" curved inwardly to terminatei'nan outlet 5 through which, the inhaling takesplace.
Fitting` over the bod-y- I is' a capA 6 the lower endi off which;A engages aA port-ion 'lonthe bod-yy; the portion 'l-Y havingj a circumferentialf ridge- 8 which co-operateswitlrraf depressionin then cap 6 to elect a spring lock of' thecap 6- to the body Ii The cap 6 has in-it a depending plug l0 which fitslinto-.theout-let 5'; at the'top of 'the-bodyv IA to seal Vthis out-let asshown'y more` particularly `in Fig. 2; f
An air inlet opening IJI", substantially smaller than the outlet 5 and having a diameter no larger than one-quarter the diameter of the outlet, is formed through the portion 'I of the body I and is arranged to direct air downwardly into the powder space of the body so that when suction is applied through the outlet 5 the air flowing in through the air inlet opening II will disturb the powder either by direct contact or by reflex currents of air set up in the container to cause the powder to be lifted with`an upward flow of air taking place within the bondy I.
In the modication shown in Fig. 4, in which similar reference numerals are used to corresponding parts, a further air inlet opening I4 is formed through the portion 1 of the body I, this air inlet opening, however, being arranged as an additional air bleed to permit a greater quantity of air to be drawn through the outlet 5 in the extension 4 of the body I.
By providing the two openings II and i4 a close control is given of the mixture of air and powder, the opening I I projecting a stream of air downwardly to disturb the powder and render at least some of it air-borne while the opening I4 admits additional air so that the ratio of air to powder being drawn through the outlet 5 gives more air for a measured quantity of powder and thus allo-ws the powder to be carried deep into the lungs or further back into the throat if such is desired. When the small opening I I only is used it will be appreciated that the amount of air flowing through the outlet 5 will be correspondingly small and the powder will settle in the nostrils or mouth more readily than is the case where a relatively large volume of air is being inhaled.
In the modication shown in Fig. 5 of which again the corresponding parts have similar reference characters, the body l kis provided with a shoulder I5 between which and the shoulder I6 of the body is disposed a rotatable sleeve I'I, the sleeve having an opening I8 which may register with the opening II in the body or may be brought into partial register only if such is desired, this then permitting the size of the opening II to be adjusted by appropriately orientating the sleeve I'I.
In use the cap 6 is simply removed from the body I and the outlet 5 placed into communication with the mouth or nostril whereupon when suction is applied the powder from the hollow 2 will be drawn up with the air depending in Volume on the size of the opening II and whether or not the additional opening I4 is used. When inhaling is completed the cap is simply replaced until such time as a further supply of the inhalant is required, the cap tting over the portion 1 of the body in the case of Figs. 1 to 4 or over the sleeve I 'I in the case of Fig. 5 to seal the air openings into the body so that when the cap is in position it closes the outlet 5 and at the same time the air inlet openings I I and I4 if used so that a hygienic and aseptic seal is formed for the container.
` The unit can be formed of plastic or any other suitable material and it will be appreciated that the openings may be duplicated if desired an may be arranged tangentially.
What I claim is:
1. An inhaler for medicinal inhalants comprising a hollow body for holding a medicinal inhalant and having an axial extension tapering to an unobstructed voutlet opening arranged axially at its end, and intermediate its ends said body having at least one straight air inlet opening extending oblquely through the wall of said body which has a diameter no greater than onequarter the diameter of said outlet opening and arranged to admit air into said hollow body in a direction away from said outlet opening when suction is applied to the latter, a cap to engage said body intermediate the ends oi' the latter and fit over said extension for sealing said inlet opening, and a stopper projecting axially within said cap to extend through and seal said outlet opening.
2. An inhaler according to claim 1; wherein said body has an additional straight air inlet opening extending obliquely through the side wall thereof intermediate its ends and arranged to admit additional air into said hollow body in the direction towards said outlet opening so that the additional air will be mixed with the medicinal mist formed by air entering through the rst mentioned inlet opening.
3. An inhaler according to claim 1; including an apertured sleeve movable on said body for selective registration with said air inlet opening to vary the effective area of the latter.
HARRY G. WILLIS.
References Cited in the file of this patent UNITED STATES PATENTS Number Name Date 263,451 Adams Aug. 29, 1882 439,707 Warren Nov. 4, 1890 545,679 Cills Sept. 3, 1895 567,558 Wiseman Sept. 8, 1896
US223184A 1950-05-19 1951-04-27 Inhaler for medicinal substances Expired - Lifetime US2672865A (en)

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Cited By (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2966909A (en) * 1956-12-14 1961-01-03 A E Halperin Co Inc Pocket inhalator
US3255750A (en) * 1963-12-13 1966-06-14 Schwartzman Sam Inhaler
US3938516A (en) * 1975-01-13 1976-02-17 Syntex Puerto Rico, Inc. Inhalation device
US3973566A (en) * 1975-01-13 1976-08-10 Syntex Puerto Rico Inc. Inhalation device
US3980074A (en) * 1973-07-18 1976-09-14 Beecham Group Limited Device for the administration of powders
US4014336A (en) * 1975-01-13 1977-03-29 Syntex Puerto Rico, Inc. Inhalation device
US4083368A (en) * 1976-09-01 1978-04-11 Freezer Winthrop J Inhaler
US4307734A (en) * 1980-06-23 1981-12-29 B & B Inventors & Marketers, Inc. Snuff dispenser
US5161524A (en) * 1991-08-02 1992-11-10 Glaxo Inc. Dosage inhalator with air flow velocity regulating means
US5388573A (en) * 1993-12-02 1995-02-14 Tenax Corporation Dry powder inhalator medicament carrier
US5388572A (en) * 1993-10-26 1995-02-14 Tenax Corporation (A Connecticut Corp.) Dry powder medicament inhalator having an inhalation-activated piston to aerosolize dose and deliver same
US5460173A (en) * 1993-03-03 1995-10-24 Tenax Corporation Dry powder inhaler medicament carrier
US5483954A (en) * 1994-06-10 1996-01-16 Mecikalski; Mark B. Inhaler and medicated package
US5673686A (en) * 1994-02-02 1997-10-07 Plurichemie Anstalt Medicament inhaler and method
WO1999013930A1 (en) * 1997-09-18 1999-03-25 Glaxo Group Limited Intranasal administration device
US6116239A (en) * 1997-08-07 2000-09-12 Art Slutsky Inhalation device
US6142145A (en) * 1997-03-14 2000-11-07 Astra Aktiebolag Inhalation device
US20070209661A1 (en) * 2006-03-03 2007-09-13 Hugh Smyth Dry powder inhaler with aeroelastic dispersion mechanism
US8561609B2 (en) 2010-12-07 2013-10-22 Respira Therapeutics, Inc. Dry powder inhaler
US9492625B2 (en) 2009-11-12 2016-11-15 Stc.Unm Dry powder inhaler with flutter dispersion member
US10441733B2 (en) 2012-06-25 2019-10-15 Respira Therapeutics, Inc. Powder dispersion devices and methods
US11471623B2 (en) 2012-02-21 2022-10-18 Respira Therapeutics, Inc. Powder dispersion methods and devices

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US263451A (en) * 1882-08-29 adams
US439707A (en) * 1890-11-04 Said warren
US545679A (en) * 1895-09-03 Eemedial powdee
US567558A (en) * 1896-09-08 Inhaler

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US263451A (en) * 1882-08-29 adams
US439707A (en) * 1890-11-04 Said warren
US545679A (en) * 1895-09-03 Eemedial powdee
US567558A (en) * 1896-09-08 Inhaler

Cited By (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2966909A (en) * 1956-12-14 1961-01-03 A E Halperin Co Inc Pocket inhalator
US3255750A (en) * 1963-12-13 1966-06-14 Schwartzman Sam Inhaler
US3980074A (en) * 1973-07-18 1976-09-14 Beecham Group Limited Device for the administration of powders
US3938516A (en) * 1975-01-13 1976-02-17 Syntex Puerto Rico, Inc. Inhalation device
US3973566A (en) * 1975-01-13 1976-08-10 Syntex Puerto Rico Inc. Inhalation device
US4014336A (en) * 1975-01-13 1977-03-29 Syntex Puerto Rico, Inc. Inhalation device
US4083368A (en) * 1976-09-01 1978-04-11 Freezer Winthrop J Inhaler
US4307734A (en) * 1980-06-23 1981-12-29 B & B Inventors & Marketers, Inc. Snuff dispenser
US5161524A (en) * 1991-08-02 1992-11-10 Glaxo Inc. Dosage inhalator with air flow velocity regulating means
US5460173A (en) * 1993-03-03 1995-10-24 Tenax Corporation Dry powder inhaler medicament carrier
US5388572A (en) * 1993-10-26 1995-02-14 Tenax Corporation (A Connecticut Corp.) Dry powder medicament inhalator having an inhalation-activated piston to aerosolize dose and deliver same
US5388573A (en) * 1993-12-02 1995-02-14 Tenax Corporation Dry powder inhalator medicament carrier
US5673686A (en) * 1994-02-02 1997-10-07 Plurichemie Anstalt Medicament inhaler and method
AU698047B2 (en) * 1994-02-02 1998-10-22 Hovione Inter Ltd Medicament inhaler and method
US5483954A (en) * 1994-06-10 1996-01-16 Mecikalski; Mark B. Inhaler and medicated package
US5575281A (en) * 1994-06-10 1996-11-19 Mecikalski; Mark B. Medicated package
US5568807A (en) * 1994-06-10 1996-10-29 Mecikalski; Mark B. Air-flow control for an inhaler
US6142145A (en) * 1997-03-14 2000-11-07 Astra Aktiebolag Inhalation device
US6116239A (en) * 1997-08-07 2000-09-12 Art Slutsky Inhalation device
US6575160B1 (en) 1997-08-07 2003-06-10 Art Slutsky Inhalation device
WO1999013930A1 (en) * 1997-09-18 1999-03-25 Glaxo Group Limited Intranasal administration device
US20070209661A1 (en) * 2006-03-03 2007-09-13 Hugh Smyth Dry powder inhaler with aeroelastic dispersion mechanism
US9492625B2 (en) 2009-11-12 2016-11-15 Stc.Unm Dry powder inhaler with flutter dispersion member
US8561609B2 (en) 2010-12-07 2013-10-22 Respira Therapeutics, Inc. Dry powder inhaler
US8651104B2 (en) 2010-12-07 2014-02-18 Respira Therapeutics, Inc. Bead-containing dry powder inhaler
US11471623B2 (en) 2012-02-21 2022-10-18 Respira Therapeutics, Inc. Powder dispersion methods and devices
US10441733B2 (en) 2012-06-25 2019-10-15 Respira Therapeutics, Inc. Powder dispersion devices and methods

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