US20220175576A1 - Proximal Mounting of Temperature Sensor in Intravascular Temperature Management Catheter - Google Patents
Proximal Mounting of Temperature Sensor in Intravascular Temperature Management Catheter Download PDFInfo
- Publication number
- US20220175576A1 US20220175576A1 US17/550,687 US202117550687A US2022175576A1 US 20220175576 A1 US20220175576 A1 US 20220175576A1 US 202117550687 A US202117550687 A US 202117550687A US 2022175576 A1 US2022175576 A1 US 2022175576A1
- Authority
- US
- United States
- Prior art keywords
- catheter
- temperature
- joining body
- temperature sensor
- proximal
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000012530 fluid Substances 0.000 claims abstract description 24
- 239000008280 blood Substances 0.000 claims abstract description 20
- 210000004369 blood Anatomy 0.000 claims abstract description 20
- 210000004204 blood vessel Anatomy 0.000 claims abstract description 8
- 239000000919 ceramic Substances 0.000 claims description 10
- 229920000642 polymer Polymers 0.000 claims description 5
- 229910044991 metal oxide Inorganic materials 0.000 claims description 4
- 150000004706 metal oxides Chemical class 0.000 claims description 4
- 238000000034 method Methods 0.000 claims description 4
- 230000002792 vascular Effects 0.000 abstract 1
- 206010021113 Hypothermia Diseases 0.000 description 5
- 230000002631 hypothermal effect Effects 0.000 description 4
- 239000003507 refrigerant Substances 0.000 description 3
- 208000010496 Heart Arrest Diseases 0.000 description 2
- 208000006011 Stroke Diseases 0.000 description 2
- 208000030886 Traumatic Brain injury Diseases 0.000 description 2
- 229910002113 barium titanate Inorganic materials 0.000 description 2
- 239000002826 coolant Substances 0.000 description 2
- 239000003814 drug Substances 0.000 description 2
- 238000001802 infusion Methods 0.000 description 2
- 238000007917 intracranial administration Methods 0.000 description 2
- 239000000463 material Substances 0.000 description 2
- 208000010125 myocardial infarction Diseases 0.000 description 2
- 230000001225 therapeutic effect Effects 0.000 description 2
- 230000009529 traumatic brain injury Effects 0.000 description 2
- 206010037660 Pyrexia Diseases 0.000 description 1
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 1
- 208000032851 Subarachnoid Hemorrhage Diseases 0.000 description 1
- 230000001668 ameliorated effect Effects 0.000 description 1
- JRPBQTZRNDNNOP-UHFFFAOYSA-N barium titanate Chemical compound [Ba+2].[Ba+2].[O-][Ti]([O-])([O-])[O-] JRPBQTZRNDNNOP-UHFFFAOYSA-N 0.000 description 1
- 239000011324 bead Substances 0.000 description 1
- 238000004891 communication Methods 0.000 description 1
- 230000008878 coupling Effects 0.000 description 1
- 238000010168 coupling process Methods 0.000 description 1
- 238000005859 coupling reaction Methods 0.000 description 1
- 230000002939 deleterious effect Effects 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 239000000835 fiber Substances 0.000 description 1
- 239000011888 foil Substances 0.000 description 1
- 229910052751 metal Inorganic materials 0.000 description 1
- 239000002184 metal Substances 0.000 description 1
- 239000004065 semiconductor Substances 0.000 description 1
- 230000008054 signal transmission Effects 0.000 description 1
- 239000011780 sodium chloride Substances 0.000 description 1
- 210000001631 vena cava inferior Anatomy 0.000 description 1
- 210000002620 vena cava superior Anatomy 0.000 description 1
- 238000010792 warming Methods 0.000 description 1
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F7/00—Heating or cooling appliances for medical or therapeutic treatment of the human body
- A61F7/12—Devices for heating or cooling internal body cavities
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F7/00—Heating or cooling appliances for medical or therapeutic treatment of the human body
- A61F2007/0054—Heating or cooling appliances for medical or therapeutic treatment of the human body with a closed fluid circuit, e.g. hot water
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F7/00—Heating or cooling appliances for medical or therapeutic treatment of the human body
- A61F2007/0054—Heating or cooling appliances for medical or therapeutic treatment of the human body with a closed fluid circuit, e.g. hot water
- A61F2007/0056—Heating or cooling appliances for medical or therapeutic treatment of the human body with a closed fluid circuit, e.g. hot water for cooling
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F7/00—Heating or cooling appliances for medical or therapeutic treatment of the human body
- A61F2007/0086—Heating or cooling appliances for medical or therapeutic treatment of the human body with a thermostat
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F7/00—Heating or cooling appliances for medical or therapeutic treatment of the human body
- A61F2007/0093—Heating or cooling appliances for medical or therapeutic treatment of the human body programmed
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F7/00—Heating or cooling appliances for medical or therapeutic treatment of the human body
- A61F2007/0095—Heating or cooling appliances for medical or therapeutic treatment of the human body with a temperature indicator
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F7/00—Heating or cooling appliances for medical or therapeutic treatment of the human body
- A61F2007/0095—Heating or cooling appliances for medical or therapeutic treatment of the human body with a temperature indicator
- A61F2007/0096—Heating or cooling appliances for medical or therapeutic treatment of the human body with a temperature indicator with a thermometer
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F7/00—Heating or cooling appliances for medical or therapeutic treatment of the human body
- A61F7/12—Devices for heating or cooling internal body cavities
- A61F2007/126—Devices for heating or cooling internal body cavities for invasive application, e.g. for introducing into blood vessels
Definitions
- the present application relates generally to heat exchange systems for patient temperature control with proximally mounted joining bodies or ceramic portions of an onboard temperature sensor.
- Patient temperature control systems have been introduced to prevent fever in patients in the neuro ICU due to suffering from sub-arachnoid hemorrhage or other neurologic malady such as stroke. Also, such systems have been used to induce mild or moderate hypothermia to improve the outcomes of patients suffering from such maladies as stroke, cardiac arrest, myocardial infarction, traumatic brain injury, and high intracranial pressure. Moreover, such systems have been used for warming purposes such as for burn patients and other patients who may suffer from deleterious or accidental hypothermia. Examples of intravascular heat exchange catheters are disclosed in U.S. Pat. Nos.
- External patient temperature control systems may be used. Such systems are disclosed in U.S. Pat. Nos. 6,827,728, 6,818,012, 6,802,855, 6,799,063, 6,764,391, 6,692,518, 6,669,715, 6,660,027, 6,648,905, 6,645,232, 6,620,187, 6,461,379, 6,375,674, 6,197,045, and 6,188,930 (collectively, “the external pad patents”), all of which are incorporated herein by reference.
- One or more of the above-referenced catheters may be equipped with a temperature sensor on the catheter to sense the temperature of blood flowing past the catheter. The temperature signal is fed back to the controller of one or more of the above-referenced systems and used to control the temperature of the working fluid circulating through the catheter.
- the desirability of minimizing the diameter of the catheter limits space on the intubated portion of the catheter that is available to support a temperature sensor.
- an intravascular temperature management catheter incudes a catheter shaft through which working fluid can circulate to and from a proximal location on the shaft.
- the catheter extends from a connector hub.
- At least one heat exchange member is supported by a part of the shaft, e.g., a distal part of the shaft, or by a catheter spine or other catheter portion, to receive circulating working fluid from the proximal location.
- One or more temperature sensors are supported on or in the catheter for generating a temperature signal representative of blood temperature to a control system.
- the temperature sensor includes first and second conductive leads having respective first and second distal segments on or in the catheter shaft.
- the first and second distal segments are arranged to be in thermal contact with blood flowing past the catheter when the catheter is disposed in a blood vessel of a patient.
- the temperature sensor includes a joining body connected to proximal segments of the first and second leads, wherein the temperature sensor is positioned or oriented such that the joining body is in a location which is proximal to the first and second conductive leads, e.g., the joining body may be supported on or in the hub, an electrical connector or in another location proximal to the hub.
- the temperature sensor may be a thermistor or other type of temperature sensor or detector, including but not limited to thermocouples, resistance temperature detectors (RTDs), or fiberoptic temperature sensors.
- the temperature sensor can be a negative temperature coefficient (NTC) thermistor or a positive temperature coefficient (PTC) thermistor.
- NTC negative temperature coefficient
- PTC positive temperature coefficient
- the joining body may be made of various materials, e.g., a polymer or a ceramic.
- the joining body can be made of sintered metal oxide.
- the joining body without limitation, may be made of a doped polycrystalline ceramic.
- a thermally conductive cover can physically shield the first and second distal segments from contact with blood flowing past the catheter when the catheter is disposed in a blood vessel of a patient.
- a method in another aspect, includes thermally exposing first and second distal segments of first and second leads of one or more temperature sensors mounted on or in a closed loop intravascular temperature management catheter to blood flowing past the catheter.
- the method includes receiving a signal representing blood temperature from a joining body, e.g., a ceramic or polymer joining body, connected to the leads, wherein the temperature sensor is positioned or oriented such that the joining body is disposed in a location which is proximal to at least a portion of the first and second conductive leads or distal segments of the leads and/or disposed on or in a proximal hub of the catheter, an electrical connector, or in a location proximal to the hub, and sending the signal to a control system for controlling a temperature of working fluid flowing through the catheter in a closed loop.
- a joining body e.g., a ceramic or polymer joining body
- a device in another aspect, has a catheter shaft through which working fluid can circulate and one or more temperature sensors supported on or in the device for generating a temperature signal.
- the temperature sensor includes first and second conductive leads having respective first and second distal segments arranged to be in thermal contact with blood flowing past the catheter when the catheter is disposed in a blood vessel of a patient.
- the temperature sensor has a joining body connected to proximal segments of the first and second leads, with the joining body being supported in a location proximal to the distal segments of the first and second leads.
- the temperature sensor may be positioned or oriented such that the joining body is in a location which is proximal to at least a portion of the distal segments of the first and second conductive leads, e.g., supported on or in the hub, an electrical connector, or in location proximal to a hub.
- FIG. 1 is a schematic view of a non-limiting system in accordance with an embodiment of the present invention
- FIG. 2 is a perspective view of an example catheter
- FIG. 3 is a cross-section taken along the line 3 - 3 in FIG. 2 ;
- FIG. 4 is a close up view of the top portion of the structure shown in circle 4 in FIG. 3 .
- a system 10 may include one or more intravascular heat exchange catheters 12 controlled by a control system 14 to control patient temperature, e.g., to prevent the patient 16 from becoming febrile or to induce therapeutic hypothermia in the patient 16 .
- working fluid or coolant such as but not limited to saline, circulates (typically under the influence of a pump “P” in the control system) in a closed loop from the control system 14 , through a fluid supply line L 1 , through the catheter 12 , and back to the system 14 through a fluid return line L 2 , such that no working fluid or coolant enters the body.
- the catheter 12 may be implemented by any of the catheters disclosed in the patent documents incorporated by reference herein in the following U.S. patent documents, all incorporated herein by reference: U.S. Pat. Nos.
- the catheter 12 may be placed in the venous system, e.g., in the superior or inferior vena cava.
- the system 10 may include one or more pads 18 that are positioned against the external skin of the patient 16 (only one pad 18 shown for clarity).
- the pad 18 may be, without limitation, any one of the pads disclosed in the externa) pad patents.
- the temperature of the pad 18 can be controlled by the control system 14 to exchange heat with the patient 16 , including to induce therapeutic mild or moderate hypothermia in the patient in response to the patient presenting with, e.g., cardiac arrest, myocardial infarction, stroke, high intracranial pressure, traumatic brain injury, or other malady the effects of which can be ameliorated by hypothermia.
- the pad 18 may receive working fluid from the system 14 through a fluid supply line L 3 , and return working fluid to the system 14 through a fluid return line L 4 .
- the control system 14 may include one or more microprocessors 20 receiving target and patient temperatures as input and controlling, among other things, the pump “P” and a refrigerant compressor 22 and/or a bypass valve 24 that can be opened to permit refrigerant to bypass a condenser.
- the refrigerant circulates through a heat exchanger within the control system 14 as described further below.
- the processor 20 can access non-transitory computer memory 26 to execute instructions on the memory 26 to execute control logic.
- a temperature sensor 30 e.g., a thermistor
- the catheter 12 may have one or more hollow multi-lumen shaft portions 32 (a catheter with only a single shaft shown) through which working fluid can circulate to and from a proximal location on the shaft, at which the catheter shaft extends from a connector hub 34 .
- the connector hub 34 fluidly interconnects working fluid supply and return lumens in the catheter shaft 32 to respective supply and return connector fittings 36 , 38 , which may be connected via respective tubing set connectors to the system 14 shown in FIG. 1 in which the working fluid may be heated or cooled as desired to manage patient temperature.
- the working fluid circulating in the supply and return lumens of the shaft 32 circulate into and out of one or more heat exchange members 37 that are supported by a distal part of the shaft 32 or by another part of the catheter. Any of the heat exchange members described in the patents may be used.
- a temperature connector 40 may provide electrical communication between the temperature sensor 30 and the system 14 .
- One or more electrical connectors may extend from the temperature sensor 30 through the temperature connector 40 , which may be engaged with a corresponding connector engaged with the system 14 to provide a path for electrical signal transmission from the temperature sensor 30 to the system 14 .
- a wireless transceiver may be provided, e.g., in the hub 34 to receive the temperature signal from the temperature sensor 30 and wirelessly transmit the signal to the system 14 . While three connector 36 - 40 are shown, it is to be understood that additional connectors may be provided on the hub 34 .
- a medicament infusion connector may be provided that fluidly connects an infusion lumen in the catheter shaft 32 with a source of medicament.
- FIGS. 3 and 4 best show that the temperature sensor 30 includes at least first and second conductive leads 42 , 44 having respective first and second distal segments 46 , 48 (also shown schematically in FIG. 2 ) on or in the catheter shaft 32 .
- the leads 42 , 44 may be molded into the wall of the catheter shaft 32 and extend proximally to the hub 34 , or the leads 42 , 44 , with the possible exception of the distal segments 46 , 48 , may be disposed in a lumen of the catheter shaft 32 .
- the first and second distal segments 46 , 48 are arranged to be in thermal contact with blood flowing past the catheter when the catheter is disposed in a blood vessel of a patient.
- the distal segments 46 , 48 lie on the catheter shaft parallel to the axis of the shaft and on or near the outer surface of the shaft.
- the distal segments 46 , 48 may be molded into the shaft and may lie on the outer surface, physically and thus thermally exposed to blood flowing past the catheter.
- the distal segments 46 , 48 may be covered by a thermally conductive cover 50 to physically shield the distal segments 46 , 48 from blood while thermally coupling the segments to the blood.
- the cover 50 may be established by an ultra-thin and flexible metal foil that can be wrapped around the catheter shaft 32 .
- Other materials may be used, e.g., thermally conductive plastic.
- a temperature sensor may have one or more leads.
- first and second conductive leads 42 , 44 may extend to and if desired into the hub 34 , where proximal segments of the leads are connected to a joining body 52 or body ( FIG. 3 ) which may be supported in the hub or in a location proximal to the hub, e.g., in or on a connector, such as an electrical or temperature connector. It is to be understood that electrical signals representing patient temperature are taken from the joining body 52 and sent (e.g., via a lead 54 and the temperature connector 40 ) to the system 14 according to principles described above.
- the temperature sensor may be positioned or oriented such that the joining body is in a location proximal to or proximal relative to the position of at least a portion of the first and/or second conductive leads, e.g., the distal segment of a lead, whether the joining body is positioned on or in the catheter, hub or other location proximal to the hub.
- a joining body may be located proximal to or proximal relative to at least a portion of the first and second conductive leads such that it is closer to a proximal end of the catheter, a hub or other connector than the location of at least a portion of the conductive leads is.
- the temperature sensor 30 may be a thermistor or other type of sensor or detector, including but not limited to thermocouples, resistance temperature detectors (RTDs), or fiber optic temperature sensors.
- a thermistor can be a negative temperature coefficient (NTC) or positive temperature coefficient (PTC) thermistor.
- the thermistor may include die first and second electrically conductive leads or wires 42 , 44 which may be electrically insulated within the catheter and which join the joining body 52 , which may be a ceramic or polymer body.
- NTC thermistors may have joining bodies made from a pressed disc, rod, plate, bead or cast chip of a semiconductor such as a sintered metal oxide, whereas a PTC thermistor may have a joining body made of a polycrystalline ceramic doped with barium titanate (BaTiO3).
Landscapes
- Health & Medical Sciences (AREA)
- Vascular Medicine (AREA)
- Thermal Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Physics & Mathematics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Measuring And Recording Apparatus For Diagnosis (AREA)
- Media Introduction/Drainage Providing Device (AREA)
Abstract
Description
- The present application relates generally to heat exchange systems for patient temperature control with proximally mounted joining bodies or ceramic portions of an onboard temperature sensor.
- Patient temperature control systems have been introduced to prevent fever in patients in the neuro ICU due to suffering from sub-arachnoid hemorrhage or other neurologic malady such as stroke. Also, such systems have been used to induce mild or moderate hypothermia to improve the outcomes of patients suffering from such maladies as stroke, cardiac arrest, myocardial infarction, traumatic brain injury, and high intracranial pressure. Moreover, such systems have been used for warming purposes such as for burn patients and other patients who may suffer from deleterious or accidental hypothermia. Examples of intravascular heat exchange catheters are disclosed in U.S. Pat. Nos. 6,419,643, 6,416,533, 6,409,747, 6,405,080, 6,393,320, 6,368,304, 6,338,727, 6,299,599, 6,290,717, 6,287,326, 6,165,207, 6,149,670, 6,146,411, 6,126,684, 6,306,161, 6,264,679, 6,231,594, 6,149,676, 6,149,673, 6,110,168, 5,989,238, 5,879,329, 5,837,003, 6,383,210, 6,379,378, 6,364,899, 6,325,818, 6,312,452, 6,261,312, 6,254,626, 6,251,130, 6,251,129, 6,245,095, 6,238,428, 6,235,048, 6,231,595, 6,224,624, 6,149,677, 6,096,068, 6,042,559, 8,888,729, and USPPs 2013/0178923, 2013/0079855, 2013/0079856, 2014/0094880, 2014/0094882, 2014/0094883, all of which are incorporated herein by reference.
- External patient temperature control systems may be used. Such systems are disclosed in U.S. Pat. Nos. 6,827,728, 6,818,012, 6,802,855, 6,799,063, 6,764,391, 6,692,518, 6,669,715, 6,660,027, 6,648,905, 6,645,232, 6,620,187, 6,461,379, 6,375,674, 6,197,045, and 6,188,930 (collectively, “the external pad patents”), all of which are incorporated herein by reference.
- One or more of the above-referenced catheters may be equipped with a temperature sensor on the catheter to sense the temperature of blood flowing past the catheter. The temperature signal is fed back to the controller of one or more of the above-referenced systems and used to control the temperature of the working fluid circulating through the catheter.
- As understood herein, the desirability of minimizing the diameter of the catheter limits space on the intubated portion of the catheter that is available to support a temperature sensor.
- Accordingly, an intravascular temperature management catheter incudes a catheter shaft through which working fluid can circulate to and from a proximal location on the shaft. The catheter extends from a connector hub. At least one heat exchange member is supported by a part of the shaft, e.g., a distal part of the shaft, or by a catheter spine or other catheter portion, to receive circulating working fluid from the proximal location. One or more temperature sensors are supported on or in the catheter for generating a temperature signal representative of blood temperature to a control system. The temperature sensor includes first and second conductive leads having respective first and second distal segments on or in the catheter shaft. The first and second distal segments are arranged to be in thermal contact with blood flowing past the catheter when the catheter is disposed in a blood vessel of a patient. Also, the temperature sensor includes a joining body connected to proximal segments of the first and second leads, wherein the temperature sensor is positioned or oriented such that the joining body is in a location which is proximal to the first and second conductive leads, e.g., the joining body may be supported on or in the hub, an electrical connector or in another location proximal to the hub.
- In examples, the temperature sensor may be a thermistor or other type of temperature sensor or detector, including but not limited to thermocouples, resistance temperature detectors (RTDs), or fiberoptic temperature sensors. The temperature sensor can be a negative temperature coefficient (NTC) thermistor or a positive temperature coefficient (PTC) thermistor. The joining body may be made of various materials, e.g., a polymer or a ceramic. For instance the joining body can be made of sintered metal oxide. Or, the joining body, without limitation, may be made of a doped polycrystalline ceramic. If desired, a thermally conductive cover can physically shield the first and second distal segments from contact with blood flowing past the catheter when the catheter is disposed in a blood vessel of a patient.
- In another aspect, a method includes thermally exposing first and second distal segments of first and second leads of one or more temperature sensors mounted on or in a closed loop intravascular temperature management catheter to blood flowing past the catheter. The method includes receiving a signal representing blood temperature from a joining body, e.g., a ceramic or polymer joining body, connected to the leads, wherein the temperature sensor is positioned or oriented such that the joining body is disposed in a location which is proximal to at least a portion of the first and second conductive leads or distal segments of the leads and/or disposed on or in a proximal hub of the catheter, an electrical connector, or in a location proximal to the hub, and sending the signal to a control system for controlling a temperature of working fluid flowing through the catheter in a closed loop.
- In another aspect, a device has a catheter shaft through which working fluid can circulate and one or more temperature sensors supported on or in the device for generating a temperature signal. The temperature sensor includes first and second conductive leads having respective first and second distal segments arranged to be in thermal contact with blood flowing past the catheter when the catheter is disposed in a blood vessel of a patient. Also, the temperature sensor has a joining body connected to proximal segments of the first and second leads, with the joining body being supported in a location proximal to the distal segments of the first and second leads. The temperature sensor may be positioned or oriented such that the joining body is in a location which is proximal to at least a portion of the distal segments of the first and second conductive leads, e.g., supported on or in the hub, an electrical connector, or in location proximal to a hub.
- The details of the various embodiments and aspects described herein, both as to their structure and operation, can best be understood in reference to the accompanying drawings, in which like reference numerals refer to like parts, and in which:
-
FIG. 1 is a schematic view of a non-limiting system in accordance with an embodiment of the present invention; -
FIG. 2 is a perspective view of an example catheter; -
FIG. 3 is a cross-section taken along the line 3-3 inFIG. 2 ; and -
FIG. 4 is a close up view of the top portion of the structure shown incircle 4 inFIG. 3 . - Referring initially to
FIG. 1 , in accordance with present principles, a system 10 may include one or more intravascularheat exchange catheters 12 controlled by acontrol system 14 to control patient temperature, e.g., to prevent thepatient 16 from becoming febrile or to induce therapeutic hypothermia in thepatient 16. In the catheter, working fluid or coolant, such as but not limited to saline, circulates (typically under the influence of a pump “P” in the control system) in a closed loop from thecontrol system 14, through a fluid supply line L1, through thecatheter 12, and back to thesystem 14 through a fluid return line L2, such that no working fluid or coolant enters the body. In this way, patient temperature can be managed by controlling the temperature of the working fluid as appropriate to exchange heat with the blood. Without limitation, thecatheter 12 may be implemented by any of the catheters disclosed in the patent documents incorporated by reference herein in the following U.S. patent documents, all incorporated herein by reference: U.S. Pat. Nos. 5,486,208, 5,837,003, 6,110,168, 6,149,673, 6,149,676, 6,231,594, 6,264,679, 6,306,161, 6,235,048, 6,238,428, 6,245,095, 6,251,129, 6,251,130, 6,254,626, 6,261,312, 6,312,452, 6,325,818, 6,409,747, 6,368,304, 6,338,727, 6,299,599, 6,287,326, 6,126,684, 8,888,729, and USPPs 2013/0178923, 2013/0079855, 2013/0079856, 2014/0094880, 2014/0094882, 2014/0094883. Thecatheter 12 may be placed in the venous system, e.g., in the superior or inferior vena cava. - Instead of or in addition to the
catheter 12, the system 10 may include one or more pads 18 that are positioned against the external skin of the patient 16 (only one pad 18 shown for clarity). The pad 18 may be, without limitation, any one of the pads disclosed in the externa) pad patents. The temperature of the pad 18 can be controlled by thecontrol system 14 to exchange heat with thepatient 16, including to induce therapeutic mild or moderate hypothermia in the patient in response to the patient presenting with, e.g., cardiac arrest, myocardial infarction, stroke, high intracranial pressure, traumatic brain injury, or other malady the effects of which can be ameliorated by hypothermia. The pad 18 may receive working fluid from thesystem 14 through a fluid supply line L3, and return working fluid to thesystem 14 through a fluid return line L4. - The
control system 14 may include one ormore microprocessors 20 receiving target and patient temperatures as input and controlling, among other things, the pump “P” and a refrigerant compressor 22 and/or abypass valve 24 that can be opened to permit refrigerant to bypass a condenser. The refrigerant circulates through a heat exchanger within thecontrol system 14 as described further below. Theprocessor 20 can access non-transitory computer memory 26 to execute instructions on the memory 26 to execute control logic. - As shown in the embodiment in
FIGS. 2-4 , atemperature sensor 30, e.g., a thermistor, may be supported on thecatheter 12. As shown, thecatheter 12 may have one or more hollow multi-lumen shaft portions 32 (a catheter with only a single shaft shown) through which working fluid can circulate to and from a proximal location on the shaft, at which the catheter shaft extends from aconnector hub 34. Theconnector hub 34 fluidly interconnects working fluid supply and return lumens in thecatheter shaft 32 to respective supply andreturn connector fittings system 14 shown inFIG. 1 in which the working fluid may be heated or cooled as desired to manage patient temperature. - The working fluid circulating in the supply and return lumens of the
shaft 32 circulate into and out of one or moreheat exchange members 37 that are supported by a distal part of theshaft 32 or by another part of the catheter. Any of the heat exchange members described in the patents may be used. - Additionally, a
temperature connector 40 may provide electrical communication between thetemperature sensor 30 and thesystem 14. One or more electrical connectors may extend from thetemperature sensor 30 through thetemperature connector 40, which may be engaged with a corresponding connector engaged with thesystem 14 to provide a path for electrical signal transmission from thetemperature sensor 30 to thesystem 14. Alternatively, a wireless transceiver may be provided, e.g., in thehub 34 to receive the temperature signal from thetemperature sensor 30 and wirelessly transmit the signal to thesystem 14. While three connector 36-40 are shown, it is to be understood that additional connectors may be provided on thehub 34. For example, a medicament infusion connector may be provided that fluidly connects an infusion lumen in thecatheter shaft 32 with a source of medicament. -
FIGS. 3 and 4 best show that thetemperature sensor 30 includes at least first and second conductive leads 42, 44 having respective first and seconddistal segments 46, 48 (also shown schematically inFIG. 2 ) on or in thecatheter shaft 32. Theleads catheter shaft 32 and extend proximally to thehub 34, or theleads distal segments catheter shaft 32. - In examples, the first and second
distal segments distal segments distal segments distal segments conductive cover 50 to physically shield thedistal segments cover 50 may be established by an ultra-thin and flexible metal foil that can be wrapped around thecatheter shaft 32. Other materials may be used, e.g., thermally conductive plastic. In certain embodiments, a temperature sensor may have one or more leads. - As mentioned above, the first and second conductive leads 42, 44 may extend to and if desired into the
hub 34, where proximal segments of the leads are connected to a joiningbody 52 or body (FIG. 3 ) which may be supported in the hub or in a location proximal to the hub, e.g., in or on a connector, such as an electrical or temperature connector. It is to be understood that electrical signals representing patient temperature are taken from the joiningbody 52 and sent (e.g., via alead 54 and the temperature connector 40) to thesystem 14 according to principles described above. The temperature sensor may be positioned or oriented such that the joining body is in a location proximal to or proximal relative to the position of at least a portion of the first and/or second conductive leads, e.g., the distal segment of a lead, whether the joining body is positioned on or in the catheter, hub or other location proximal to the hub. In certain embodiments, a joining body may be located proximal to or proximal relative to at least a portion of the first and second conductive leads such that it is closer to a proximal end of the catheter, a hub or other connector than the location of at least a portion of the conductive leads is. - In any of the embodiments described herein, the
temperature sensor 30 may be a thermistor or other type of sensor or detector, including but not limited to thermocouples, resistance temperature detectors (RTDs), or fiber optic temperature sensors. For example, a thermistor can be a negative temperature coefficient (NTC) or positive temperature coefficient (PTC) thermistor. The thermistor may include die first and second electrically conductive leads orwires body 52, which may be a ceramic or polymer body. For example, NTC thermistors may have joining bodies made from a pressed disc, rod, plate, bead or cast chip of a semiconductor such as a sintered metal oxide, whereas a PTC thermistor may have a joining body made of a polycrystalline ceramic doped with barium titanate (BaTiO3). - While various embodiments of a PROXIMAL MOUNTING OF TEMPERATURE SENSOR IN INTRAVASCULAR TEMPERATURE MANAGEMENT CATHETERS are herein shown and described in detail, the scope of the present invention is to be limited by nothing other than the appended claims.
Claims (21)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US17/550,687 US20220175576A1 (en) | 2015-03-31 | 2021-12-14 | Proximal Mounting of Temperature Sensor in Intravascular Temperature Management Catheter |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US14/675,452 US11213423B2 (en) | 2015-03-31 | 2015-03-31 | Proximal mounting of temperature sensor in intravascular temperature management catheter |
US17/550,687 US20220175576A1 (en) | 2015-03-31 | 2021-12-14 | Proximal Mounting of Temperature Sensor in Intravascular Temperature Management Catheter |
Related Parent Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US14/675,452 Continuation US11213423B2 (en) | 2015-03-31 | 2015-03-31 | Proximal mounting of temperature sensor in intravascular temperature management catheter |
Publications (1)
Publication Number | Publication Date |
---|---|
US20220175576A1 true US20220175576A1 (en) | 2022-06-09 |
Family
ID=57007546
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US14/675,452 Active 2037-05-17 US11213423B2 (en) | 2015-03-31 | 2015-03-31 | Proximal mounting of temperature sensor in intravascular temperature management catheter |
US17/550,687 Pending US20220175576A1 (en) | 2015-03-31 | 2021-12-14 | Proximal Mounting of Temperature Sensor in Intravascular Temperature Management Catheter |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US14/675,452 Active 2037-05-17 US11213423B2 (en) | 2015-03-31 | 2015-03-31 | Proximal mounting of temperature sensor in intravascular temperature management catheter |
Country Status (7)
Country | Link |
---|---|
US (2) | US11213423B2 (en) |
EP (1) | EP3277173A4 (en) |
JP (1) | JP2018511398A (en) |
CN (1) | CN107666888A (en) |
AU (1) | AU2016243620A1 (en) |
CA (1) | CA2981492A1 (en) |
WO (1) | WO2016160933A1 (en) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US9474644B2 (en) | 2014-02-07 | 2016-10-25 | Zoll Circulation, Inc. | Heat exchange system for patient temperature control with multiple coolant chambers for multiple heat exchange modalities |
US11033424B2 (en) | 2014-02-14 | 2021-06-15 | Zoll Circulation, Inc. | Fluid cassette with tensioned polymeric membranes for patient heat exchange system |
US10792185B2 (en) | 2014-02-14 | 2020-10-06 | Zoll Circulation, Inc. | Fluid cassette with polymeric membranes and integral inlet and outlet tubes for patient heat exchange system |
US10537465B2 (en) | 2015-03-31 | 2020-01-21 | Zoll Circulation, Inc. | Cold plate design in heat exchanger for intravascular temperature management catheter and/or heat exchange pad |
US11185440B2 (en) | 2017-02-02 | 2021-11-30 | Zoll Circulation, Inc. | Devices, systems and methods for endovascular temperature control |
US11116657B2 (en) | 2017-02-02 | 2021-09-14 | Zoll Circulation, Inc. | Devices, systems and methods for endovascular temperature control |
US10525232B2 (en) * | 2017-09-06 | 2020-01-07 | Becton, Dickinson And Company | Smart obturator assembly |
CN108498934A (en) * | 2018-04-18 | 2018-09-07 | 山东吉威医疗制品有限公司 | Glomus pulmonale ductus bursae |
WO2023101677A1 (en) * | 2021-12-02 | 2023-06-08 | C.R. Bard, Inc. | Systems, methods, and apparatus for automated feedback for targeted temperature management systems |
Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6368304B1 (en) * | 1999-02-19 | 2002-04-09 | Alsius Corporation | Central venous catheter with heat exchange membrane |
US6383144B1 (en) * | 2000-01-18 | 2002-05-07 | Edwards Lifesciences Corporation | Devices and methods for measuring temperature of a patient |
US20020101326A1 (en) * | 2001-01-26 | 2002-08-01 | Lavenuta Gregg J. | Thermistor and method of manufacture |
US20030014094A1 (en) * | 2001-07-13 | 2003-01-16 | Radiant Medical, Inc. | Catheter system with on-board temperature probe |
US20090140369A1 (en) * | 2007-11-30 | 2009-06-04 | Lee Keun-Hyuk | Semiconductor power module package without temperature sensor mounted thereon and method of fabricating the same |
US20140113828A1 (en) * | 2011-03-30 | 2014-04-24 | Ambature Inc. | Electrical, mechanical, computing/ and/or other devices formed of extremely low resistance materials |
Family Cites Families (243)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US1459112A (en) | 1922-02-23 | 1923-06-19 | Charles F Mehl | Invalid bed |
US1726761A (en) | 1926-12-15 | 1929-09-03 | Stephen L Palmer | Hot-water bottle |
US1857031A (en) | 1929-08-02 | 1932-05-03 | Schaffer Edward | Combined hoist and conveyer |
GB659339A (en) | 1948-04-26 | 1951-10-24 | Bengt Rudolf Dahlberg | Improvements in apparatus for lifting, temporarily supporting and transferring persons in a reclining position |
US2673987A (en) | 1951-10-22 | 1954-04-06 | James L Upshaw | Invalid carrier with rotatable chair |
US3225191A (en) | 1962-06-01 | 1965-12-21 | Industrial Dynamics Co | Infrared liquid level inspection system |
US3425419A (en) | 1964-08-08 | 1969-02-04 | Angelo Actis Dato | Method of lowering and raising the temperature of the human body |
US3369549A (en) | 1965-10-05 | 1968-02-20 | Thomas A. Armao | Capsule probe having thermoelectric heat exchange means therein |
US3504674A (en) | 1966-12-22 | 1970-04-07 | Emil S Swenson | Method and apparatus for performing hypothermia |
GB1163185A (en) | 1967-05-15 | 1969-09-04 | Ilford Ltd | Chemical Compounds |
US3744565A (en) | 1971-01-22 | 1973-07-10 | Cities Service Oil Co | Apparatus and process for the solution and heating of sulfur containing natural gas |
US3726269A (en) | 1971-11-24 | 1973-04-10 | W Webster | Cardiovascular catheter for thermal dilution measurement |
US3751077A (en) | 1972-02-28 | 1973-08-07 | Imp Eastman Corp | Welded sleeve fitting |
NL7414546A (en) | 1973-11-15 | 1975-05-20 | Rhone Poulenc Sa | SMOOTH HEATING TUBE AND PROCESS FOR MANUFACTURING IT. |
JPS5247636B2 (en) | 1973-12-15 | 1977-12-03 | ||
US3937224A (en) | 1974-04-11 | 1976-02-10 | Uecker Ronald L | Colostomy catheter |
US4126132A (en) | 1975-07-28 | 1978-11-21 | Andros Incorporated | Intravenous and intra arterial delivery system |
US4065264A (en) | 1976-05-10 | 1977-12-27 | Shiley Laboratories, Inc. | Blood oxygenator with integral heat exchanger for regulating the temperature of blood in an extracorporeal circuit |
US4103511A (en) | 1976-10-04 | 1978-08-01 | Firma Kress Elektrik Gmbh & Co. | Connecting arrangement for a machine tool |
US4173228A (en) | 1977-05-16 | 1979-11-06 | Applied Medical Devices | Catheter locating device |
US4181132A (en) | 1977-05-31 | 1980-01-01 | Parks Leon C | Method and apparatus for effecting hyperthermic treatment |
US4153048A (en) | 1977-09-14 | 1979-05-08 | Cleveland Clinic Foundation | Thermodilution catheter and method |
US4259961A (en) | 1979-01-24 | 1981-04-07 | Hood Iii Andrew G | Cooling pad |
US4298006A (en) | 1980-04-30 | 1981-11-03 | Research Against Cancer, Inc. | Systemic hyperthermia with improved temperature sensing apparatus and method |
US4532414A (en) | 1980-05-12 | 1985-07-30 | Data Chem., Inc. | Controlled temperature blood warming apparatus |
US4459468A (en) | 1982-04-14 | 1984-07-10 | Bailey David F | Temperature control fluid circulating system |
US5370675A (en) | 1992-08-12 | 1994-12-06 | Vidamed, Inc. | Medical probe device and method |
US4581017B1 (en) | 1983-03-07 | 1994-05-17 | Bard Inc C R | Catheter systems |
US4554793A (en) | 1983-06-09 | 1985-11-26 | General Eastern Instruments Corporation | Controlled power converter for thermoelectric heat pump drive |
JPS6028085A (en) | 1983-07-25 | 1985-02-13 | Canon Inc | Head driver of recording or reproducing device |
US4672962A (en) | 1983-09-28 | 1987-06-16 | Cordis Corporation | Plaque softening method |
US4653987A (en) | 1984-07-06 | 1987-03-31 | Tsuyoshi Tsuji | Finger peristaltic infusion pump |
US4638436A (en) | 1984-09-24 | 1987-01-20 | Labthermics Technologies, Inc. | Temperature control and analysis system for hyperthermia treatment |
US4661094A (en) | 1985-05-03 | 1987-04-28 | Advanced Cardiovascular Systems | Perfusion catheter and method |
SE8504501D0 (en) | 1985-09-30 | 1985-09-30 | Astra Meditec Ab | METHOD OF FORMING AN IMPROVED HYDROPHILIC COATING ON A POLYMER SURFACE |
CH668192A5 (en) | 1985-11-29 | 1988-12-15 | Schneider Medintag Ag | CATHETER FOR TREATING NARROW BODIES, FOR EXAMPLE IN A BLOOD VESSEL. |
US4665391A (en) | 1986-02-27 | 1987-05-12 | Warner-Lambert Company | Empty container detector |
US4754752A (en) | 1986-07-28 | 1988-07-05 | Robert Ginsburg | Vascular catheter |
JPS63159300A (en) | 1986-12-23 | 1988-07-02 | Shin Etsu Chem Co Ltd | Production of silicon carbide whisker |
US4813855A (en) | 1987-06-26 | 1989-03-21 | Tek-Aids Inc. | Peristaltic pump |
JPS6446056U (en) | 1987-09-17 | 1989-03-22 | ||
US4860744A (en) | 1987-11-02 | 1989-08-29 | Raj K. Anand | Thermoelectrically controlled heat medical catheter |
GB2212262B (en) | 1987-11-09 | 1992-07-22 | Solinst Canada Ltd | Liquid level detector |
US4852567A (en) | 1988-01-21 | 1989-08-01 | C. R. Bard, Inc. | Laser tipped catheter |
US4941475A (en) | 1988-08-30 | 1990-07-17 | Spectramed, Inc. | Thermodilution by heat exchange |
WO1990001682A1 (en) | 1988-10-20 | 1990-02-22 | Conax Buffalo Corporation | Optical liquid level sensors |
FR2693116B1 (en) | 1992-07-06 | 1995-04-28 | Technomed Int Sa | Urethral probe and apparatus for the therapeutic treatment of prostate tissue by thermotherapy. |
US5174285A (en) | 1990-01-08 | 1992-12-29 | Lake Shore Medical Development Partners Ltd. | Localized heat transfer device |
US5624392A (en) | 1990-05-11 | 1997-04-29 | Saab; Mark A. | Heat transfer catheters and methods of making and using same |
US5342301A (en) | 1992-08-13 | 1994-08-30 | Advanced Polymers Incorporated | Multi-lumen balloons and catheters made therewith |
US5092841A (en) | 1990-05-17 | 1992-03-03 | Wayne State University | Method for treating an arterial wall injured during angioplasty |
US5507792A (en) | 1990-09-05 | 1996-04-16 | Breg, Inc. | Therapeutic treatment device having a heat transfer element and a pump for circulating a treatment fluid therethrough |
US5584804A (en) | 1990-10-10 | 1996-12-17 | Life Resuscitation Technologies, Inc. | Brain resuscitation and organ preservation device and method for performing the same |
US5195965A (en) | 1991-03-07 | 1993-03-23 | Shantha Totada R | Method and apparatus for localized treatment of human viral infections and cancers |
US5381510A (en) | 1991-03-15 | 1995-01-10 | In-Touch Products Co. | In-line fluid heating apparatus with gradation of heat energy from inlet to outlet |
JP3091253B2 (en) | 1991-04-25 | 2000-09-25 | オリンパス光学工業株式会社 | Thermal treatment equipment |
US5192274A (en) | 1991-05-08 | 1993-03-09 | Bierman Steven F | Anchor pad for catheterization system |
US5211631A (en) | 1991-07-24 | 1993-05-18 | Sheaff Charles M | Patient warming apparatus |
GB9118670D0 (en) | 1991-08-30 | 1991-10-16 | Mcnicholas Thomas A | Surgical devices and uses thereof |
US5304214A (en) | 1992-01-21 | 1994-04-19 | Med Institute, Inc. | Transurethral ablation catheter |
US6059825A (en) | 1992-03-05 | 2000-05-09 | Angiodynamics, Inc. | Clot filter |
US5281215A (en) | 1992-04-16 | 1994-01-25 | Implemed, Inc. | Cryogenic catheter |
US5269758A (en) | 1992-04-29 | 1993-12-14 | Taheri Syde A | Intravascular catheter and method for treatment of hypothermia |
DE4221390C1 (en) | 1992-06-30 | 1993-04-01 | Haindl, Hans, Dr.Med., 3015 Wennigsen, De | |
US5403281A (en) | 1992-09-25 | 1995-04-04 | Minnesota Mining And Manufacturing Company | Inline heat exchanger and cardioplegia system |
US6325067B1 (en) | 1992-12-03 | 2001-12-04 | Wesley D. Sterman | Methods and systems for performing thoracoscopic coronary bypass and other procedures |
US5437673A (en) | 1993-02-04 | 1995-08-01 | Cryomedical Sciences, Inc. | Closed circulation tissue warming apparatus and method of using the same in prostate surgery |
US5837003A (en) | 1993-02-10 | 1998-11-17 | Radiant Medical, Inc. | Method and apparatus for controlling a patient's body temperature by in situ blood temperature modification |
US6620188B1 (en) | 1998-08-24 | 2003-09-16 | Radiant Medical, Inc. | Methods and apparatus for regional and whole body temperature modification |
US6110168A (en) | 1993-02-10 | 2000-08-29 | Radiant Medical, Inc. | Method and apparatus for controlling a patient's body temperature by in situ blood temperature modifications |
US5486208A (en) | 1993-02-10 | 1996-01-23 | Ginsburg; Robert | Method and apparatus for controlling a patient's body temperature by in situ blood temperature modification |
US5383856A (en) | 1993-03-19 | 1995-01-24 | Bersin; Robert M. | Helical spiral balloon catheter |
US5626618A (en) | 1993-09-24 | 1997-05-06 | The Ohio State University | Mechanical adjunct to cardiopulmonary resuscitation (CPR), and an electrical adjunct to defibrillation countershock, cardiac pacing, and cardiac monitoring |
US5387088A (en) | 1994-01-18 | 1995-02-07 | Haemonetics Corporation | Peristaltic pump tube loading assembly |
US6716216B1 (en) | 1998-08-14 | 2004-04-06 | Kyphon Inc. | Systems and methods for treating vertebral bodies |
JP3442863B2 (en) | 1994-06-10 | 2003-09-02 | 隆 松浦 | Patient bed with release frame and moving device for release frame |
US5716386A (en) | 1994-06-27 | 1998-02-10 | The Ohio State University | Non-invasive aortic impingement and core and cerebral temperature manipulation |
US5458639A (en) | 1994-08-05 | 1995-10-17 | Medtronic, Inc. | Catheter balloon distal bond |
EP0698940B1 (en) | 1994-08-24 | 2000-06-14 | Sumitomo Wiring Systems, Ltd. | Wiring circuit for an electrical connection box, method and apparatus for forming the wiring circuit |
US5486207A (en) | 1994-09-20 | 1996-01-23 | Mahawili; Imad | Thermal pad for portable body heating/cooling system and method of use |
US5895418A (en) | 1994-09-30 | 1999-04-20 | Saringer Research Inc. | Device for producing cold therapy |
US5531714A (en) | 1994-11-01 | 1996-07-02 | M. Patricia Lange | Self-guiding, multifunctional visceral catheter |
US5634907A (en) | 1994-12-22 | 1997-06-03 | Sandoz Nutrition Ltd. | System for detection of fluid infusion |
US5980561A (en) | 1995-03-01 | 1999-11-09 | Kolen; Paul T. | Applying thermal therapy to living tissue |
US5596995A (en) | 1995-05-02 | 1997-01-28 | Heart Rhythm Technologies, Inc. | Biomedical device having a temperature sensing system |
US6149806A (en) | 1995-05-12 | 2000-11-21 | Baer; William | Two piece frame and two piece diaphragm filter plate |
DE19531935A1 (en) | 1995-08-17 | 1997-02-20 | Panagiotis Tsolkas | Device for whole body hyperthermia treatment |
US5730720A (en) | 1995-08-18 | 1998-03-24 | Ip Scientific, Inc. | Perfusion hyperthermia treatment system and method |
US5686658A (en) * | 1995-10-05 | 1997-11-11 | Asttest Services, Inc. | Aboveground liquid storage tank leakage detection |
US5701905A (en) | 1995-11-13 | 1997-12-30 | Localmed, Inc. | Guide catheter with sensing element |
US5759017A (en) | 1996-01-31 | 1998-06-02 | Medtronic Electromedics, Inc. | Peristaltic pump and tube loading system |
DE29602173U1 (en) | 1996-02-08 | 1997-06-26 | B. Braun Melsungen Ag, 34212 Melsungen | Application device for medical liquids |
US5733319A (en) | 1996-04-25 | 1998-03-31 | Urologix, Inc. | Liquid coolant supply system |
US5676670A (en) | 1996-06-14 | 1997-10-14 | Beth Israel Deaconess Medical Center | Catheter apparatus and method for creating a vascular bypass in-vivo |
US5776079A (en) | 1996-08-06 | 1998-07-07 | Cook Incorporated | Retrograde-antegrade catheterization guide wire |
DE59709319D1 (en) | 1996-10-02 | 2003-03-20 | Kehl Hermann | LASER GUN |
JPH10127777A (en) | 1996-10-31 | 1998-05-19 | Sumitomo Bakelite Co Ltd | Pharmaceutical liquid injecting port |
US5893885A (en) | 1996-11-01 | 1999-04-13 | Cordis Webster, Inc. | Multi-electrode ablation catheter |
US5849016A (en) | 1996-12-03 | 1998-12-15 | Suhr; William S. | Catheter exchange method and apparatus |
US6124452A (en) | 1997-12-19 | 2000-09-26 | University Of Nebraska-Lincoln | Octafluoro-meso-tetraarylporphyrins and methods for making these compounds |
US5879329A (en) | 1997-01-22 | 1999-03-09 | Radiant Medical, Inc. | Infusion systems and methods for introducing fluids into the body within a desired temperature range |
US5788647A (en) | 1997-01-24 | 1998-08-04 | Eggers; Philip E. | Method, system and apparatus for evaluating hemodynamic parameters |
US6110097A (en) | 1997-03-06 | 2000-08-29 | Scimed Life Systems, Inc. | Perfusion balloon catheter with radioactive source |
AU6457298A (en) | 1997-03-12 | 1998-09-29 | Advanced Closure Systems, Inc. | Vascular sealing device |
JPH10305103A (en) | 1997-05-08 | 1998-11-17 | Nippon Sherwood Medical Ind Ltd | Catheter fixing tool |
US5862675A (en) | 1997-05-30 | 1999-01-26 | Mainstream Engineering Corporation | Electrically-driven cooling/heating system utilizing circulated liquid |
US5908407A (en) | 1997-07-25 | 1999-06-01 | Neuroperfusion, Inc. | Retroperfusion catheter apparatus and method |
US6283940B1 (en) | 1997-08-29 | 2001-09-04 | S. Grant Mulholland | Catheter |
US6110139A (en) | 1997-10-21 | 2000-08-29 | Loubser; Paul Gerhard | Retrograde perfusion monitoring and control system |
US6042599A (en) | 1997-11-12 | 2000-03-28 | Bionix Development Corp. | Tissue approximation forceps |
WO1999029363A1 (en) | 1997-12-08 | 1999-06-17 | Cardeon Corporation | Aortic catheter and methods for inducing cardioplegic arrest and for selective aortic perfusion |
US6379378B1 (en) | 2000-03-03 | 2002-04-30 | Innercool Therapies, Inc. | Lumen design for catheter |
US6238428B1 (en) | 1998-01-23 | 2001-05-29 | Innercool Therapies, Inc. | Selective organ cooling apparatus and method employing turbulence-inducing element with curved terminations |
US6245095B1 (en) | 1998-03-24 | 2001-06-12 | Innercool Therapies, Inc. | Method and apparatus for location and temperature specific drug action such as thrombolysis |
US6325818B1 (en) | 1999-10-07 | 2001-12-04 | Innercool Therapies, Inc. | Inflatable cooling apparatus for selective organ hypothermia |
US6231595B1 (en) | 1998-03-31 | 2001-05-15 | Innercool Therapies, Inc. | Circulating fluid hypothermia method and apparatus |
US6719779B2 (en) | 2000-11-07 | 2004-04-13 | Innercool Therapies, Inc. | Circulation set for temperature-controlled catheter and method of using the same |
US6464716B1 (en) | 1998-01-23 | 2002-10-15 | Innercool Therapies, Inc. | Selective organ cooling apparatus and method |
US6096068A (en) | 1998-01-23 | 2000-08-01 | Innercool Therapies, Inc. | Selective organ cooling catheter and method of using the same |
US6051019A (en) | 1998-01-23 | 2000-04-18 | Del Mar Medical Technologies, Inc. | Selective organ hypothermia method and apparatus |
US6843800B1 (en) | 1998-01-23 | 2005-01-18 | Innercool Therapies, Inc. | Patient temperature regulation method and apparatus |
US6312452B1 (en) * | 1998-01-23 | 2001-11-06 | Innercool Therapies, Inc. | Selective organ cooling catheter with guidewire apparatus and temperature-monitoring device |
US6251130B1 (en) | 1998-03-24 | 2001-06-26 | Innercool Therapies, Inc. | Device for applications of selective organ cooling |
US6261312B1 (en) | 1998-06-23 | 2001-07-17 | Innercool Therapies, Inc. | Inflatable catheter for selective organ heating and cooling and method of using the same |
US7458984B2 (en) * | 1998-01-23 | 2008-12-02 | Innercool Therapies, Inc. | System and method for inducing hypothermia with active patient temperature control employing catheter-mounted temperature sensor and temperature projection algorithm |
US6251129B1 (en) | 1998-03-24 | 2001-06-26 | Innercool Therapies, Inc. | Method for low temperature thrombolysis and low temperature thrombolytic agent with selective organ temperature control |
US6383210B1 (en) | 2000-06-02 | 2002-05-07 | Innercool Therapies, Inc. | Method for determining the effective thermal mass of a body or organ using cooling catheter |
US6254626B1 (en) | 1998-03-24 | 2001-07-03 | Innercool Therapies, Inc. | Articulation device for selective organ cooling apparatus |
US6974463B2 (en) * | 1999-02-09 | 2005-12-13 | Innercool Therapies, Inc. | System and method for patient temperature control employing temperature projection algorithm |
US6149624A (en) | 1998-02-05 | 2000-11-21 | Mcshane; Richard Houston | Apparatus and method for the rapid induction of hypothermic brain preservation |
US6042559A (en) | 1998-02-24 | 2000-03-28 | Innercool Therapies, Inc. | Insulated catheter for selective organ perfusion |
US6599312B2 (en) | 1998-03-24 | 2003-07-29 | Innercool Therapies, Inc. | Isolated selective organ cooling apparatus |
US6224624B1 (en) | 1998-03-24 | 2001-05-01 | Innercool Therapies, Inc. | Selective organ cooling apparatus and method |
DE19814695C2 (en) | 1998-04-01 | 2001-09-13 | Fresenius Medical Care De Gmbh | Cassette for conveying liquids, in particular dialysis liquids, dialysis machine and method for conveying, balancing, dosing and heating a medical fluid |
US6338727B1 (en) | 1998-08-13 | 2002-01-15 | Alsius Corporation | Indwelling heat exchange catheter and method of using same |
US6530946B1 (en) | 1998-04-21 | 2003-03-11 | Alsius Corporation | Indwelling heat exchange heat pipe catheter and method of using same |
US6419643B1 (en) | 1998-04-21 | 2002-07-16 | Alsius Corporation | Central venous catheter with heat exchange properties |
US6126684A (en) | 1998-04-21 | 2000-10-03 | The Regents Of The University Of California | Indwelling heat exchange catheter and method of using same |
US6149670A (en) | 1999-03-11 | 2000-11-21 | Alsius Corporation | Method and system for treating cardiac arrest using hypothermia |
US6450990B1 (en) | 1998-08-13 | 2002-09-17 | Alsius Corporation | Catheter with multiple heating/cooling fibers employing fiber spreading features |
US6312461B1 (en) | 1998-08-21 | 2001-11-06 | John D. Unsworth | Shape memory tubular stent |
US6428563B1 (en) | 2000-01-21 | 2002-08-06 | Radiant Medical, Inc. | Heat exchange catheter with improved insulated region |
US6610083B2 (en) | 1998-08-24 | 2003-08-26 | Radiant Medical, Inc. | Multiple lumen heat exchange catheters |
US6673098B1 (en) | 1998-08-24 | 2004-01-06 | Radiant Medical, Inc. | Disposable cassette for intravascular heat exchange catheter |
EP1119394A4 (en) | 1998-09-11 | 2004-07-07 | Medivance Inc | Method and apparatus for providing localized heating of the preoptic anterior hypothalamus |
JP3438624B2 (en) | 1998-12-01 | 2003-08-18 | ウシオ電機株式会社 | Lamp blackening detection method |
US6146411A (en) | 1998-12-24 | 2000-11-14 | Alsius Corporation | Cooling system for indwelling heat exchange catheter |
US6197045B1 (en) | 1999-01-04 | 2001-03-06 | Medivance Incorporated | Cooling/heating pad and system |
DE60023118T2 (en) | 1999-01-04 | 2006-07-13 | Medivance, Inc., Louisville | IMPROVED COOLING / HEATING CUSHION AND SYSTEM |
US6060461A (en) | 1999-02-08 | 2000-05-09 | Drake; James Franklin | Topically applied clotting material |
US6869440B2 (en) * | 1999-02-09 | 2005-03-22 | Innercool Therapies, Inc. | Method and apparatus for patient temperature control employing administration of anti-shivering agents |
US6299599B1 (en) | 1999-02-19 | 2001-10-09 | Alsius Corporation | Dual balloon central venous line catheter temperature control system |
US6405080B1 (en) | 1999-03-11 | 2002-06-11 | Alsius Corporation | Method and system for treating cardiac arrest |
US6019783A (en) | 1999-03-02 | 2000-02-01 | Alsius Corporation | Cooling system for therapeutic catheter |
US6290717B1 (en) | 1999-03-31 | 2001-09-18 | Alsius Corporation | Temperature probe and interconnect cable for hypothermia catheter temperature feedback |
US6148634A (en) | 1999-04-26 | 2000-11-21 | 3M Innovative Properties Company | Multistage rapid product refrigeration apparatus and method |
US6165207A (en) | 1999-05-27 | 2000-12-26 | Alsius Corporation | Method of selectively shaping hollow fibers of heat exchange catheter |
US6436071B1 (en) | 1999-06-08 | 2002-08-20 | The Trustees Of Columbia University In The City Of New York | Intravascular systems for corporeal cooling |
US6287326B1 (en) | 1999-08-02 | 2001-09-11 | Alsius Corporation | Catheter with coiled multi-lumen heat transfer extension |
US6231594B1 (en) | 1999-08-11 | 2001-05-15 | Radiant Medical, Inc. | Method of controlling body temperature while reducing shivering |
US6264679B1 (en) | 1999-08-20 | 2001-07-24 | Radiant Medical, Inc. | Heat exchange catheter with discrete heat exchange elements |
US20040089058A1 (en) | 1999-09-09 | 2004-05-13 | De Haan Peter Hillebrand | Sensor for detecting the presence of moisture |
US6554791B1 (en) | 1999-09-29 | 2003-04-29 | Smisson-Cartledge Biomedical, Llc | Rapid infusion system |
US6464666B1 (en) | 1999-10-08 | 2002-10-15 | Augustine Medical, Inc. | Intravenous fluid warming cassette with stiffening member and integral handle |
WO2001026719A1 (en) | 1999-10-08 | 2001-04-19 | Augustine Medical, Inc. | Pressure tolerant parenteral fluid and blood container for a warming cassette |
GB9926980D0 (en) | 1999-11-15 | 2000-01-12 | Medivance Instr Limited | Improved pneumatic device |
AU4713601A (en) | 1999-12-07 | 2001-06-18 | Alsius Corporation | Method and system for treating stroke using hypothermia |
US6811551B2 (en) | 1999-12-14 | 2004-11-02 | Radiant Medical, Inc. | Method for reducing myocardial infarct by application of intravascular hypothermia |
US6624679B2 (en) | 2000-01-31 | 2003-09-23 | Stmicroelectronics S.R.L. | Stabilized delay circuit |
WO2001076517A2 (en) | 2000-04-07 | 2001-10-18 | The General Hospital Corporation D/B/A Massachusetts General Hospital | Methods and apparatus for thermally affecting tissue |
WO2001083001A1 (en) | 2000-05-02 | 2001-11-08 | Vasca, Inc. | Methods and devices for draining fluids in and out of the body |
US6955174B2 (en) * | 2000-08-18 | 2005-10-18 | Uryovascular Systems, Inc. | Cryotherapy method for detecting and treating vulnerable plaque |
US6551309B1 (en) | 2000-09-14 | 2003-04-22 | Cryoflex, Inc. | Dual action cryoprobe and methods of using the same |
US6719723B2 (en) | 2000-12-06 | 2004-04-13 | Innercool Therapies, Inc. | Multipurpose catheter assembly |
US6544282B1 (en) | 2001-02-21 | 2003-04-08 | Radiant Medical, Inc. | Inhibition of platelet activation, aggregation and/or adhesion by hypothermia |
US6753783B2 (en) | 2001-03-30 | 2004-06-22 | Augmentech, Inc. | Patient positioning monitoring apparatus and method of use thereof |
US6699269B2 (en) | 2001-04-30 | 2004-03-02 | Rohit K. Khanna | Selective brain and spinal cord hypothermia method and apparatus |
US6461379B1 (en) | 2001-04-30 | 2002-10-08 | Medivance, Incorporated | Localized bodily cooling/heating apparatus and method |
JP4354150B2 (en) * | 2001-05-02 | 2009-10-28 | 株式会社沖データ | Image forming apparatus |
DE10121722A1 (en) | 2001-05-04 | 2002-11-07 | Cognis Deutschland Gmbh | Gemini surfactants in rinse aid |
US7057273B2 (en) | 2001-05-15 | 2006-06-06 | Gem Services, Inc. | Surface mount package |
US6752786B2 (en) | 2001-05-31 | 2004-06-22 | Radiant Medical, Inc. | Moving heat exchange catheter system |
US6706060B2 (en) | 2001-06-05 | 2004-03-16 | Alsius Corporation | Heat exchange catheter |
US6818012B2 (en) | 2001-10-11 | 2004-11-16 | Medivance, Incorporated | Patient temperature control system with fluid temperature response |
US6660027B2 (en) | 2001-10-11 | 2003-12-09 | Medivance Incorporated | Patient temperature control system with fluid preconditioning |
GB0125294D0 (en) | 2001-10-22 | 2001-12-12 | Bickford Smith Philip | Medical small-bore tubing connectors |
US8226605B2 (en) | 2001-12-17 | 2012-07-24 | Medical Solutions, Inc. | Method and apparatus for heating solutions within intravenous lines to desired temperatures during infusion |
US6669715B2 (en) | 2002-02-27 | 2003-12-30 | Medivance Incorporated | Medical thermal energy exchange pad |
US6692518B2 (en) | 2002-02-27 | 2004-02-17 | Medivance Incorporated | Patient temperature control system |
US6799063B2 (en) | 2002-02-27 | 2004-09-28 | Medivance Incorporated | Temperature control pads with integral electrodes |
US6685733B1 (en) | 2002-04-10 | 2004-02-03 | Radiant Medical, Inc. | Methods and systems for reducing substance-induced renal damage |
US6969399B2 (en) | 2002-07-11 | 2005-11-29 | Life Recovery Systems Hd, Llc | Apparatus for altering the body temperature of a patient |
US6878156B1 (en) | 2002-07-26 | 2005-04-12 | Alsius Corporation | Portable cooler for heat exchange catheter |
US6802855B2 (en) | 2002-08-08 | 2004-10-12 | Medivance Incorporated | Patient temperature control system connector apparatus |
US6827728B2 (en) | 2002-08-08 | 2004-12-07 | Medivance Incorporated | Patient temperature control system |
CA2760543C (en) * | 2002-09-12 | 2013-08-13 | Zoll Circulation, Inc. | System and method for determining and controlling core body temperature |
US6887263B2 (en) | 2002-10-18 | 2005-05-03 | Radiant Medical, Inc. | Valved connector assembly and sterility barriers for heat exchange catheters and other closed loop catheters |
US6959758B2 (en) | 2002-12-03 | 2005-11-01 | Modine Manufacturing Company | Serpentine tube, cross flow heat exchanger construction |
US20040167467A1 (en) * | 2003-02-21 | 2004-08-26 | Kent Harrison | Delivering cooled fluid to sites inside the body |
US7300453B2 (en) * | 2003-02-24 | 2007-11-27 | Innercool Therapies, Inc. | System and method for inducing hypothermia with control and determination of catheter pressure |
US7001418B2 (en) | 2003-04-30 | 2006-02-21 | Alsius Corporation | Intravascular heat exchange catheter with insulated coolant tubes |
US6799342B1 (en) | 2003-05-27 | 2004-10-05 | Robert G. Jarmon | Method and apparatus for supporting a body |
US20050156744A1 (en) | 2003-09-02 | 2005-07-21 | Pires Harold G. | Diaper wetness annunciator system |
US7326195B2 (en) | 2003-11-18 | 2008-02-05 | Boston Scientific Scimed, Inc. | Targeted cooling of tissue within a body |
FR2863162B1 (en) | 2003-12-05 | 2006-12-08 | Vygon | MALE FITTINGS AND FEMALE FITTINGS FOR REALIZING LIQUID TRANSMISSION CONNECTIONS, IN PARTICULAR FOR ENTERALE NUTRITION LINES |
US20060064146A1 (en) | 2004-09-17 | 2006-03-23 | Collins Kenneth A | Heating/cooling system for indwelling heat exchange catheter |
US7377935B2 (en) | 2004-09-24 | 2008-05-27 | Life Recovery Systems Hd, Llc | Apparatus for altering the body temperature of a patient |
US7070612B1 (en) | 2005-02-23 | 2006-07-04 | Alsius Corporation | System and method for bringing hypothermia rapidly onboard |
US7892269B2 (en) | 2005-04-18 | 2011-02-22 | Zoll Circulation, Inc. | External heat exchange pad for patient |
EP3187157A1 (en) | 2005-04-27 | 2017-07-05 | ZOLL Circulation, Inc. | Apparatus & method for providing enhanced heat transfer from a body |
WO2007002946A2 (en) * | 2005-06-29 | 2007-01-04 | Radiant Medical, Inc. | Devices, systems and methods for rapid endovascular cooling |
US7827815B2 (en) | 2006-04-18 | 2010-11-09 | Medivance, Inc. | Apparatus and method for cooling liquid in intravascular cooling system |
US20080009578A1 (en) * | 2006-07-10 | 2008-01-10 | General Electric Company | Composition and associated method |
US7909819B2 (en) * | 2006-09-01 | 2011-03-22 | Applied Medical Resources Corporation | Monopolar electrosurgical return electrode |
US7822485B2 (en) | 2006-09-25 | 2010-10-26 | Zoll Circulation, Inc. | Method and apparatus for spinal cooling |
US8283602B2 (en) | 2007-03-19 | 2012-10-09 | Augustine Temperature Management LLC | Heating blanket |
US20080262409A1 (en) | 2007-04-23 | 2008-10-23 | Joel Brian Derrico | High flow rate disposable cassette heat exchanger |
US8272857B2 (en) | 2008-02-22 | 2012-09-25 | Medtronic Xomed, Inc. | Method and system for loading of tubing into a pumping device |
CN103892836B (en) * | 2008-05-01 | 2016-04-20 | 斯波瑞申有限公司 | Direct lung sensing system and equipment |
US20150105659A1 (en) * | 2008-11-11 | 2015-04-16 | Covidien Lp | Energy delivery device and methods of use |
TWM356018U (en) | 2008-11-21 | 2009-05-01 | Duen-Gang Mou | Torsion-spring-mounted peristaltic pump and dynamic mechanism thereof |
CN201436692U (en) * | 2009-02-12 | 2010-04-07 | 上海比亚迪有限公司 | Cylindrical lithium secondary cell cap component and cell using the cap component |
US8671940B2 (en) | 2010-01-22 | 2014-03-18 | Carleton Technologies, Inc. | Life support and microclimate integrated system and process with internal and external active heating |
US9980765B2 (en) * | 2010-02-15 | 2018-05-29 | The General Hospital Corporation | Methods and devices for selective disruption of visceral fat by controlled cooling |
US9220559B2 (en) * | 2010-09-24 | 2015-12-29 | Ethicon Endo-Surgery, Inc. | Articulation joint features for articulating surgical device |
US8613762B2 (en) | 2010-12-20 | 2013-12-24 | Medical Technology Inc. | Cold therapy apparatus using heat exchanger |
EP2720741A1 (en) | 2011-06-20 | 2014-04-23 | Veinux ApS | Disposable heat exchange cassette and an assembly for heat exchange with an intravenous fluid |
US9259348B2 (en) * | 2011-09-28 | 2016-02-16 | Zoll Circulation, Inc. | Transatrial patient temperature control catheter |
US9314370B2 (en) | 2011-09-28 | 2016-04-19 | Zoll Circulation, Inc. | Self-centering patient temperature control catheter |
US10045881B2 (en) | 2011-09-28 | 2018-08-14 | Zoll Circulation, Inc. | Patient temperature control catheter with helical heat exchange paths |
EP2760395B1 (en) | 2011-09-30 | 2017-02-22 | Zoll Circulation, Inc. | Heat exchange catheters with bi-directional fluid flow |
US9610392B2 (en) | 2012-06-08 | 2017-04-04 | Fresenius Medical Care Holdings, Inc. | Medical fluid cassettes and related systems and methods |
US20130333675A1 (en) * | 2012-06-13 | 2013-12-19 | General Electric Company | Sensor assembly with protective coating and method of applying same |
US9468715B2 (en) | 2012-09-17 | 2016-10-18 | Micrel Medical Devices S.A. | Infusion rotary peristaltic pump |
US9241827B2 (en) | 2012-09-28 | 2016-01-26 | Zoll Circulation, Inc. | Intravascular heat exchange catheter with multiple spaced apart discrete coolant loops |
US9801756B2 (en) | 2012-09-28 | 2017-10-31 | Zoll Circulation, Inc. | Intravascular heat exchange catheter and system with RFID coupling |
US9717625B2 (en) | 2012-09-28 | 2017-08-01 | Zoll Circulation, Inc. | Intravascular heat exchange catheter with non-round coiled coolant path |
US9433528B2 (en) | 2012-09-28 | 2016-09-06 | Zoll Circulation, Inc. | Intravascular heat exchange catheter with rib cage-like coolant path |
AU2014225626B2 (en) * | 2013-03-06 | 2018-02-15 | Cerora, Inc. | Form factors for the multi-modal physiological assessment of brain health |
US9402687B2 (en) * | 2013-03-13 | 2016-08-02 | Ethicon Endo-Surgery, Llc | Robotic electrosurgical device with disposable shaft |
US20150101316A1 (en) * | 2013-10-14 | 2015-04-16 | General Electric Company | Heater assembly with protective coating and method of applying same |
CN106413611A (en) * | 2014-04-17 | 2017-02-15 | 波士顿科学国际有限公司 | Medical devices for therapeutic heat treatments |
EP3157455A1 (en) * | 2014-06-20 | 2017-04-26 | Boston Scientific Scimed, Inc. | Medical device for sympathetic nerve ablation with printed components |
-
2015
- 2015-03-31 US US14/675,452 patent/US11213423B2/en active Active
-
2016
- 2016-03-30 CA CA2981492A patent/CA2981492A1/en not_active Abandoned
- 2016-03-30 CN CN201680030647.6A patent/CN107666888A/en active Pending
- 2016-03-30 WO PCT/US2016/024932 patent/WO2016160933A1/en unknown
- 2016-03-30 EP EP16774074.5A patent/EP3277173A4/en active Pending
- 2016-03-30 JP JP2017549799A patent/JP2018511398A/en active Pending
- 2016-03-30 AU AU2016243620A patent/AU2016243620A1/en not_active Abandoned
-
2021
- 2021-12-14 US US17/550,687 patent/US20220175576A1/en active Pending
Patent Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6368304B1 (en) * | 1999-02-19 | 2002-04-09 | Alsius Corporation | Central venous catheter with heat exchange membrane |
US6383144B1 (en) * | 2000-01-18 | 2002-05-07 | Edwards Lifesciences Corporation | Devices and methods for measuring temperature of a patient |
US20020101326A1 (en) * | 2001-01-26 | 2002-08-01 | Lavenuta Gregg J. | Thermistor and method of manufacture |
US20030014094A1 (en) * | 2001-07-13 | 2003-01-16 | Radiant Medical, Inc. | Catheter system with on-board temperature probe |
US20090140369A1 (en) * | 2007-11-30 | 2009-06-04 | Lee Keun-Hyuk | Semiconductor power module package without temperature sensor mounted thereon and method of fabricating the same |
US20140113828A1 (en) * | 2011-03-30 | 2014-04-24 | Ambature Inc. | Electrical, mechanical, computing/ and/or other devices formed of extremely low resistance materials |
Also Published As
Publication number | Publication date |
---|---|
AU2016243620A1 (en) | 2017-11-02 |
US11213423B2 (en) | 2022-01-04 |
WO2016160933A1 (en) | 2016-10-06 |
US20160287433A1 (en) | 2016-10-06 |
CA2981492A1 (en) | 2016-10-06 |
EP3277173A4 (en) | 2018-12-05 |
JP2018511398A (en) | 2018-04-26 |
EP3277173A1 (en) | 2018-02-07 |
CN107666888A (en) | 2018-02-06 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
US20220175576A1 (en) | Proximal Mounting of Temperature Sensor in Intravascular Temperature Management Catheter | |
US7822485B2 (en) | Method and apparatus for spinal cooling | |
US10596029B2 (en) | Intravascular heat exchange catheter with rib cage-like coolant path | |
US20080119757A1 (en) | Temperature management system with wireless patient temperature sensor | |
US9314370B2 (en) | Self-centering patient temperature control catheter | |
US7070612B1 (en) | System and method for bringing hypothermia rapidly onboard | |
US9717625B2 (en) | Intravascular heat exchange catheter with non-round coiled coolant path | |
US20060276864A1 (en) | Systems and methods for sensing patient temperature in temperature management system | |
US20110137249A1 (en) | System and method for bringing hypothermia rapidly onboard | |
US7867266B2 (en) | Temperature management system with assist mode for use with heart-lung machine | |
EP1788992A2 (en) | Heating/cooling system for indwelling heat exchange catheter | |
JP6043357B2 (en) | Transatrial patient temperature control catheter | |
JP5905969B2 (en) | System and method for dual use of a patient temperature control catheter | |
US20040215163A1 (en) | Intravascular heat exchange catheter with multiple coolant inlet holes to balloon |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
AS | Assignment |
Owner name: ZOLL CIRCULATION, INC., CALIFORNIA Free format text: ASSIGNMENT OF ASSIGNORS INTEREST;ASSIGNOR:MAZZONE, JAMES;REEL/FRAME:058517/0960 Effective date: 20150330 |
|
STPP | Information on status: patent application and granting procedure in general |
Free format text: DOCKETED NEW CASE - READY FOR EXAMINATION |
|
STPP | Information on status: patent application and granting procedure in general |
Free format text: NON FINAL ACTION MAILED |
|
STPP | Information on status: patent application and granting procedure in general |
Free format text: ADVISORY ACTION MAILED |
|
STPP | Information on status: patent application and granting procedure in general |
Free format text: NON FINAL ACTION MAILED |
|
STPP | Information on status: patent application and granting procedure in general |
Free format text: RESPONSE TO NON-FINAL OFFICE ACTION ENTERED AND FORWARDED TO EXAMINER |
|
STPP | Information on status: patent application and granting procedure in general |
Free format text: FINAL REJECTION COUNTED, NOT YET MAILED |
|
STPP | Information on status: patent application and granting procedure in general |
Free format text: FINAL REJECTION MAILED |