JPH10127777A - Pharmaceutical liquid injecting port - Google Patents

Abstract

PROBLEM TO BE SOLVED: To provide a pharmaceutical liquid injecting port which can be embedded without giving an unreasonable tension to the skin and which is low invasive and safe for the patient by sealing a liquid injection hole with a resilient piece, shaping it convex both on the oversurface and undersurface or either thereof (central part to have a greater thickness), and making the body of a non-metal material. SOLUTION: A pharmaceutical liquid injecting port 1 is configured with an internal space for storing the liquid, a resilient piece 3 for sealing mounted at a liquid injection hole 2, and a connector 6 for connection of a catheter 11. A holder 7 to press the piece 3 is furnished in the upper part of the port 1 while a bottom surface part 8 for receiving an injection needle is provided in the lower part. The resilient piece 3 should have a self-sealing property, and is formed with the central part given a greater thickness from a resilient substance having good durability with needle sticking and good adaptability to vital organism, for example, rubber of silicone. That is, both the oversurface and undersurface or either thereof are made convex. Because remaining within the vital organism for a long period, the body of this injecting port 1 is made of a non-metal material having excellent adaptability to vital organism, for example such resins as polyurethane or polyether sulfone. As the level of the port 1 is identical to the top of the holder 7 and the top of the resilient piece 3, the value can be suppressed to under 10mm, and also it is practicable to preclude generation of dead cavity with the injection hole 2.

Description

DETAILED DESCRIPTION OF THE INVENTION

[0001]

TECHNICAL FIELD The present invention relates to an intraarterial infusion of an anticancer drug in chemotherapy for an advanced cancer patient, intravenous infusion for nutritional supplementation, administration of an analgesic to the dura mater for analgesia, and to a diabetic patient. The present invention relates to a medicinal solution injection system that can be implanted subcutaneously for continuously and periodically injecting a medicinal solution into a specific part of a patient's body for a long period of time, such as insulin administration.

[0002]

2. Description of the Related Art Chemotherapy is administered to unresectable malignant tumors by administering anticancer drugs. However, systemic administration causes side effects. And the terminal was left exposed outside the body as an anticancer drug injection port, or the catheter was reinserted each time the anticancer drug was administered. (Arterial Infusion Therapy) Also, in the case of continuous infusion of high-calorie infusion, the tip of the catheter was placed in the central vein and the terminal was exposed outside the body as an infusion inlet. (IVH)

[0003] For this reason, prevention of infection from the skin wound where a catheter is inserted is a matter of concern, but keeping the skin wound clean at all times is extremely difficult in real life, and the patient's free behavior and bathing are difficult. There were also restrictions on this, and this was a major obstacle to rehabilitation. As a solution to such a problem, a subcutaneously implantable catheter assembly that can be used while being left in the body for a long time has been developed. The catheter assembly has an internal space for storing a drug solution, a drug solution inlet compressed and mounted with a cylindrical elastic body communicating with the internal space, and a port body having a drug solution outflow passage provided with a connector, A catheter provided with a lumen for injecting a drug solution, and a catheter connected to the connector such that the lumen communicates with the outflow channel.

The subcutaneous implantable catheter assembly is placed in a state where a catheter is inserted into a target blood vessel or the like and a drug solution injection port is fixed to a subcutaneous tissue. Then, when injecting the drug solution, the drug solution inlet port of the drug solution injection port is confirmed by palpation from above the skin, and the drug solution is sent into the port body by puncturing the elastic body of the drug solution inlet port with a syringe needle. A drug solution is injected into a target blood vessel or the like via the. The site where the drug solution injection port is to be implanted is mainly the chest, abdomen,
In recent years, both arterial infusion therapy and IVH use the subclavian arteries and veins, and therefore, they are often implanted in the chest. However, when implanted in a thin patient, the top of the skin rubs against clothing and the like, causing redness and inflammation.

Conventionally, the main body of the liquid injection port is made of a medically usable metal such as stainless steel or titanium, a medically available resin such as silicone, polyurethane, polyethersulfone, or a combination of the aforementioned metal and resin. Is made up of In recent years, a resin-only port that is not affected by an image due to a magnetic field such as MRI used for diagnostic imaging is desired. However, when the elastic body is compressed and mounted with resin alone, the elastic body pressing portion has a compression force of the elastic body. Because of the possibility of deformation due to body temperature, it is not possible to apply a strong compressive force to extremely reduce the thickness of the elastic body. Therefore, as shown in FIG. The sum of (internal space thickness) and (bottom portion thickness) was required. At least 12 mm or more was required, although details of each thickness will be described later. In addition, since a strong compressive force cannot be applied to the elastic body, the elastic body does not protrude, and a dead space (space) is formed at the liquid injection port due to a step with the elastic body pressing portion, and there is a risk of infection due to propagation of various bacteria. There was also.

[0006]

SUMMARY OF THE INVENTION An object of the present invention is to solve the conventional problems described above, and the thickness of the port is reduced to 10 even though the main body is made of non-metal.
mm or less, so it can be embedded into the skin, such as the chest, with thin subcutaneous fat without applying excessive tension to the skin.
Furthermore, since there is no space in the liquid inlet, the risk of infection and the like is reduced, and a low-invasive and safe liquid inlet for the patient is provided.

[0007]

That is, the present invention provides an internal space for storing a chemical solution, a chemical liquid inlet communicating with the internal space, an elastic body for sealing the chemical liquid inlet, and the internal space. And a chemical liquid outflow passage communicating with the liquid medicine outflow path, and a chemical liquid injecting port provided with a connector at the tip of the chemical liquid outflow path, wherein the shape of the elastic body is convex at one of the upper and lower sides or one side (the center is thick). In addition, the liquid injector port is characterized in that the main body is made of non-metal and the height of the main body is 10 mm or less.

[0008]

DETAILED DESCRIPTION OF THE PREFERRED EMBODIMENTS The present invention will be described below in detail with reference to the drawings. FIG. 1 is a view showing one embodiment of a chemical injection port according to the present invention, and FIG. 2 is a side view showing an elastic body used for the chemical injection port according to the present invention.

As shown in FIG. 1, the liquid injection port (1) of the present invention.
Has an internal space (4) for storing a chemical solution, and has a chemical solution inlet (2) on which an elastic body (3) is mounted,
Further, a drug solution outflow path (5) is provided in one radial direction, and a connector (6) for connecting the catheter (11) is provided at the tip of the channel. Further, the upper part of the liquid injection port (1) comprises an elastic body pressing part (7) for pressing the elastic body (3), and the lower part comprises a bottom part (8) for receiving the injection needle. As the body material,
It is necessary to be superior in biocompatibility to long-term indwelling in a living body, and it is desirable that the heat deformation temperature is 70 ° C. or more, which is about twice the body temperature, for example, polyurethane,
Resins such as polyethersulfone and silicone rubber, or a combination thereof may be used. Also, the elastic body (3) has a convex upper side in advance as shown in FIGS. 2 (a) and 2 (b) or a convex upper and lower sides as shown in FIG. The outer periphery is thin, and the material is an elastic substance having self-sealing properties.For example, rubber such as silicone, isoprene, latex, etc. can be considered. It can be used if it has excellent biocompatibility. Further, the material of the connector (6) is preferably a metal such as stainless steel or titanium from the viewpoint of strength, but is not limited. The chemical injection port (1) is assembled by insert molding, bonding and welding of the above components.

Next, the thickness of the chemical injection port (1) of the present invention will be described with reference to FIGS. As described above, the thickness of the chemical solution injection port is made up of the thickness of the elastic body pressing portion + the thickness of the elastic body + the thickness of the internal space + the thickness of the bottom portion. The thickness of the elastic body pressing part (7) depends on the thickness of the connected catheter (11).
Must be strong enough to keep the elastic body (3) from falling off at an internal pressure of about 10 kg / cm2, which is generated when a liquid medicine is injected when the body is bent in the body or the lumen is blocked by a thrombus, etc. A dimension of 2 mm or more is required. The thickness of the elastic body (3) is generally required to be needle puncture durability that can withstand 2,000 or more times when an injection needle is used, and a dimension of 5 mm or more is required to satisfy this performance. The thickness of the internal space (4) is 3 mm, which is the length of the needle hole at the tip of the injection needle.
The above thickness is required. In addition, the bottom (8) has a 2
A thickness of at least mm is required.

As described above, the thickness of the conventional liquid injection port (1) shown in FIG. 3 is at least 12 mm, but the thickness of the liquid injection port (1) of the present invention shown in FIG. Since the top of the part (7) and the top of the elastic body (3) almost coincide with each other, the thickness can be reduced to 10 mm, and as a result, a dead space (space) is eliminated in the liquid inlet (2). . Next, the method of use will be described.
The drug solution injection port (1) is embedded between the subcutaneous fat layer and the fascia layer, the drug solution inlet (2) is confirmed by palpation from above the skin, and the elastic body (3) of the drug solution inlet (2) is injected. The drug solution is sent into the port body by puncturing with a needle, and the drug solution is injected into a target blood vessel or the like via the catheter (11).

[0012]

As described above, the drug solution injection port according to the present invention is non-metallic and can be used for diagnostic imaging such as MRI, and can be implanted subcutaneously without applying excessive tension to the patient's skin. It is extremely useful as a tool which can perform selective infusion of a drug solution safely with less invasiveness.

[Brief description of the drawings]

FIG. 1 is a side sectional view showing a chemical solution injection port according to one embodiment of the present invention.

FIG. 2 is a side view showing three types of elastic bodies of a chemical liquid injection port according to one embodiment of the present invention.

FIG. 3 is a side sectional view showing a conventional chemical injection port.

[Explanation of symbols]

 DESCRIPTION OF SYMBOLS 1 Chemical injection port 2 Chemical injection port 3 Elastic body 4 Internal space 5 Chemical outflow path 6 Connector 7 Elastic body holding part 8 Bottom part 11 Catheter

Claims (2)

[Claims] 1. An internal space for storing a chemical solution, a chemical liquid inlet communicating with the internal space, an elastic body sealing the chemical liquid inlet, and a chemical liquid outflow passage communicating with the internal space. A liquid injection port provided with a connector at the tip of the liquid outflow path, wherein the elastic body has a convex shape at one of the upper and lower sides or one side (the center is thicker) and the material of the main body is nonmetallic; A liquid injection port. 2. The chemical injection port according to claim 1, wherein the height of the main body is 10 mm or less.