JP2000005322A - Medical liquid injection port - Google Patents

Abstract

PROBLEM TO BE SOLVED: To obtain a medicinal liquid injection port which enables the insertion of a filament in addition to ordinary medicinal liquid injection and is adaptable to various kinds of applications by exclusively installing the medicinal liquid injection port and filament insertion port respectively communicating with an internal space storing a medicinal liquid and sealing the both port with respective elastic bodies. SOLUTION: The medicinal liquid injection port 1 is embedded between the patient's subcutaneous fat and the fascia layer, is indwelt in the blood vessel and is connected to a catheter 11. Ordinary medicinal liquid administration is executed by pricking an elastic body 3 of the medicinal liquid injection port 2 with a needle of injection and injecting the medicinal liquid into the blood vessel from the main body of the port 1 via the catheter 11 connected to a connector 6. On the other hand, and the time treatment such as embolectomy, angiography or repair of the catheter 11, a doctor makes palpation from above the skin and confirms the filament insertion port 7, then pricks the elastic body 8 with a needle with a canula and removes the needle to indwell only the canula 13. The filament 14, such as a guide wire, is thereafter inserted into the canula 13 and is inserted down to the desired blood vessel in perspective.

Description

DETAILED DESCRIPTION OF THE INVENTION

[0001]

The present invention relates to an arterial infusion of an anticancer agent in chemotherapy for an advanced cancer patient, intravenous infusion for nutritional supplementation, administration of an analgesic agent to the meninges for analgesia, and to a diabetic patient. The present invention relates to a medicinal solution injection system that can be implanted subcutaneously for continuously and periodically injecting a medicinal solution into a specific part of a patient's body for a long period of time, such as insulin administration.

[0002]

2. Description of the Related Art Chemotherapy is administered to unresectable malignant tumors by administering anticancer drugs. However, systemic administration causes side effects. And the terminal was left exposed outside the body as an anticancer drug injection port, or the catheter was reinserted each time the anticancer drug was administered. (Arterial infusion chemotherapy) Also, in the case of continuous infusion of high-calorie infusion, the catheter tip was placed in the central vein and the terminal was exposed outside the body as an infusion inlet. (IVH) For this reason, prevention of infection from the skin wound where a catheter is inserted is a matter of concern, but keeping the skin wound clean at all times is extremely difficult in real life, and the patient's free behavior and bathing There were also restrictions on this, and this was a major obstacle to rehabilitation.

As a means for solving such a problem, a subcutaneously implantable catheter assembly which can be used while being left in the body for a long time has been developed. This catheter assembly has an internal space for storing a drug solution, and a drug solution inlet compression-mounted with a columnar elastic body communicating with the internal space at the top,
And a port main body having a drug solution outflow passage provided with a connector, and a catheter formed with a lumen for injecting a drug solution, wherein a catheter is connected to the connector such that the lumen communicates with the outflow passage. The subcutaneous implantable catheter assembly is placed in a state where the catheter is inserted into a target blood vessel or the like and the drug solution injection port is fixed to the subcutaneous tissue. And when injecting the drug solution, check the drug solution inlet of the drug solution injection port by palpation from above the skin,
The drug solution is sent into the port body by puncturing the elastic body of the drug solution inlet with an injection needle, and injected into a target blood vessel or the like via a catheter.

[0004] Up to this point, the conventional method has been used at the liquid injection port, but as a further application, the blood flow is modified according to the healing condition of the tumor, so that the liquid is more effective and has less side effects. Administration becomes feasible.
In this case, it is necessary to inject a contrast agent or an embolic substance to modify the blood flow on the peripheral side of the indwelling catheter, but if these highly coagulable drugs are injected into the drug solution injection port, the system may become clogged. Therefore, the micro catheter is inserted from another route other than the drug solution injection port. However, in order to insert a microcatheter or the like into the tip of the indwelling catheter more quickly, it is clear that it is quick and reliable to use the drug solution injection port and the route in the indwelling catheter. In the liquid injection port, the liquid injection port was almost perpendicular to the connector, so that a microcatheter or the like could not be inserted.

In order to solve this problem, a liquid injection port for inserting a filament such as a microcatheter has been disclosed in Japanese Patent Application Laid-Open No. 64-77076 and Japanese Patent Application Laid-Open No. 8-501008.
However, since the internal space is long and vertically long for the conventional liquid injection, the feel of the needle tip of the injection needle hitting the bottom surface is not obtained, and there is a possibility of puncture by mistake. there were. In particular, erroneous puncture at the time of injection of an anticancer drug can be a serious complication leading to skin necrosis. Therefore, it is very important that the puncture can be performed by an injection operation using a top puncture in the same manner as a conventional technique, which is used by operators. In addition, the puncture of the injection needle due to the frequent injection of the drug solution is rarely performed, but the puncture of the large-diameter cannula needle for inserting the filament is also performed on the elastic body. Had a remarkable durability problem.

[0006]

SUMMARY OF THE INVENTION An object of the present invention is to solve the above-mentioned conventional problems. Since a chemical solution inlet and a filament insertion port are provided exclusively, respectively, the present invention is different from the prior art. Similarly, the present invention provides a safer liquid injection port that can be used not only for performing liquid injection but also for various uses such as embolization, angiography, and modification of an indwelling catheter.

[0007]

That is, the present invention provides an internal space for storing a chemical solution, a chemical liquid inlet communicating with the internal space, an elastic body for sealing the chemical liquid inlet, and the internal space. And a connector at the tip of the drug solution outflow path, and a filament insertion port communicating with the internal space at a port rear end wall facing the connector, and sealing the filament insertion port. A chemical solution injection port provided with an elastic body having an inner diameter that continuously decreases from the internal space to the inner cavity of the connector.

[0008]

DETAILED DESCRIPTION OF THE PREFERRED EMBODIMENTS The present invention will be described below in detail with reference to the drawings. FIG. 1 is a view showing one embodiment of a chemical injection port according to the present invention, and FIG. 2 is a top view of an internal space, a chemical outflow passage, and a connector showing one embodiment of the chemical injection port according to the present invention. As shown in FIG. 1, the drug solution injection port (1) of the present invention has an internal space (4) for storing a drug solution, and has a drug solution inlet (2) having an elastic body (3) mounted thereon, Further, a drug solution outflow channel (5) is provided in one radial direction, and a connector (6) for connecting a catheter is provided at the tip of the drug solution outflow channel (5).
A filament insertion port (7) provided with an elastic body (8) is provided on the opposite side by 80 degrees.

The chemical liquid inlet (2) is provided at the top of the port as in the prior art, and is preferably a filament insertion port (7).
It is desirable that the angle α with respect to the port bottom face be in the opposite direction at an angle of 60 to 90 degrees in order to facilitate the determination of the elastic needle (8). ) Is not desirable because of the possibility of damaging it. Then, the angle β with respect to the port bottom face is 0 in the direction opposite to the liquid inlet 2 in the filament insertion port 7.
It is desirable to have an inclination of up to 30 degrees, and if it is more than 30 degrees, it will not be more than 30 degrees with the drug solution outflow path (5) and the connector (6) located parallel to the bottom of the port, and it will be difficult to insert the filament. The size of the drug solution inlet (2) is desirably wide to blindly puncture the injection needle as in the past, but it is appropriate to have a diameter of about 10 to 13 mm in view of the pressure resistance, and the sealed elastic body ( The thickness of 3) is desirably about 5 ± 2 mm. On the other hand, the size of the filament insertion port (7) is about 5 to 8 mm without being too wide for guiding the filament to the drug solution outflow path (5) and the connector (6) later. In order to puncture a needle with a cannula, it is desirable that the elastic body (8) be thicker, about 7 ± 2 mm.

As described above, the inside diameter of the chemical solution outflow path (5) is continuously reduced in order to guide the filament to the connector (6), and as shown in FIG. ) It is most desirable that the diameter is continuously reduced to the inner diameter of the rear end, including prevention of stagnation of the chemical solution.
Since the inner space (4) is required to have a shape without dead space so that the liquid medicine does not stay, the position of the distal end face (10) of the elastic body (8) sealed with the filament insertion opening (7) is adjusted to the inner space ( It is desirable that the position coincides with the side wall surface position of 4). Further, it is more desirable to provide a projection (9) on the outer periphery of the chemical solution inlet (2) and the filament insertion port (7) for facilitating discrimination by palpation.

Next, each material will be described. The main body material of the liquid injection port (1) needs to be superior in biocompatibility to a long-term indwelling in a living body, and the heat deformation temperature is lower than the body temperature. Desirably, the temperature is 70 ° C. or more, which is about twice as high, and for example, a resin such as polyurethane, polyethersulfone, or silicone rubber, a metal such as stainless steel or titanium, or a combination thereof may be used.
In particular, the use of the metal on the bottom surface of the internal space where the puncture needle contacts is one of the preferred embodiments. The material of the elastic bodies (3) and (8) is an elastic substance having self-sealing properties, for example, rubber such as silicone, isoprene, latex, etc., but soft vinyl chloride or polyurethane resin. However, it can be used if it has excellent needle sticking durability and biocompatibility. Further, the material of the connector (6) is preferably a metal such as stainless steel or titanium from the viewpoint of strength, but is not limited. The chemical injection port (1) is assembled by insert molding, bonding and welding of the above components.

Next, the method of use will be described with reference to FIG. The drug solution injection port (1) is connected to a catheter embedded between the subcutaneous fat layer and the fascia layer and placed in the blood vessel. In normal drug administration, as shown in FIG. 3a, the drug solution inlet (2) is confirmed by palpation from above the skin, and the elastic body (3) of the drug solution inlet (2) is punctured with the injection needle (12). To send the drug solution into the port (1) body, and inject the drug solution into a target blood vessel or the like via the catheter (11). Then, a method for performing a procedure such as embolization, angiography, and release of clogging due to deviation correction or bending of the catheter, etc. by inserting a microcatheter or the like through the drug solution injection port (1) and the catheter (11). 3b, the filament insertion port (7) is confirmed by palpation from above the skin, and the elastic body (8) is punctured with a puncture needle with a cannula (13), as in the case of administration of the drug solution as shown in FIG. 3b. And leave only the cannula (13). A filament (14) such as a guide wire or a microcatheter used for the treatment is cannulated (13).
To the target blood vessel under fluoroscopy, and perform the target treatment. In this case, it is preferable to use a cannula-equipped puncture needle having a tip with no needle hole such as a pencil point because the durability of the elastic body (8) can be improved.

[0013]

As described above, in the chemical liquid injection port according to the present invention, the chemical liquid injection port and the filament insertion port are provided respectively for exclusive use, so that the chemical liquid injection operation can be performed as in the conventional case, and the filament can be inserted. Therefore, it is extremely useful as a tool that can be performed according to each application such as embolization, angiography, and modification of an indwelling catheter.

[Brief description of the drawings]

FIG. 1 is a side sectional view showing a chemical solution injection port according to one embodiment of the present invention.

FIG. 2 is a top view showing an internal space of a chemical solution injection port, a chemical solution outflow path, and a connector according to one embodiment of the present invention.

FIG. 3 is a side sectional view showing a method of using a drug solution injection port according to an embodiment of the present invention, in which a normal drug solution is administered and b filament is inserted.

[Explanation of symbols]

 DESCRIPTION OF SYMBOLS 1 Chemical liquid injection port 8 Elastic body 2 Chemical liquid inlet 9 Protrusion 3 Elastic body 10 Elastic body tip surface 4 Internal space 11 Catheter 5 Chemical liquid outflow path 12 Chemical liquid injection needle 6 Connector 13 Cannula 7 Filament insertion port 14 Filament

Claims (5)

[Claims] 1. An internal space for storing a chemical solution, a chemical liquid inlet communicating with the internal space, an elastic body sealing the chemical liquid inlet, and a chemical liquid outflow passage communicating with the internal space. A chemical solution provided with a connector at the tip of the chemical solution outflow path, and further provided with a filament insertion port communicating with the internal space at a rear end wall of the port facing the connector, and an elastic body sealing the filament insertion port; An injection port, wherein the chemical solution outflow path has an inner diameter continuously reduced from an internal space to a connector bore. 2. A front end surface of an elastic body for sealing a filament insertion opening is formed at the same position as a side wall surface of the internal space so that there is no dead space in which a chemical solution stays in the internal space.
The described drug solution injection port. 3. The chemical liquid injection port according to claim 1, wherein the chemical liquid outflow passage has a planar cross-sectional shape surrounded by a tangent to the width of the inner cavity of the connector and an outer peripheral circle forming the internal space. 4. A chemical solution inlet for a bottom of a port is 60-9.
4. The drug solution injection port according to claim 1, wherein the filament insertion port forms an angle of 0 degree and the filament insertion port forms an angle of 0 to 30 degrees with respect to the port bottom surface in a direction opposite to the drug solution injection port. 5. The puncture part diameter at the drug solution inlet is 10 to 10.
The elastic body to be sealed at 13 mm has a thickness of 5 ± 2 mm, the diameter of the puncture portion at the filament insertion opening is 5 to 8 mm, and the thickness of the elastic body to be sealed is 7 ± 2 mm. The chemical injection port.