US20220072531A1

US20220072531A1 - Electronic pipette

Info

Publication number: US20220072531A1
Application number: US17/526,095
Authority: US
Inventors: Juha Telimaa; Mikael Lind
Original assignee: Thermo Fisher Scientific Oy
Current assignee: Thermo Fisher Scientific Oy
Priority date: 2012-02-13
Filing date: 2021-11-15
Publication date: 2022-03-10
Also published as: US10105698B2; CN104114281A; EP2814612B1; US9522395B2; CN108031501B; WO2013121109A1; CN108031501A; ES2713392T3; WO2013121097A1; US20170100712A1; US20190046970A1; CN104254397A; US20150013476A1; EP2814612A1; CN104114281B; EP2814614A1; US20150000429A1

Abstract

An electronic pipette comprising a piston actuated in a cylinder by a motor, a control system for carrying out pipette operations, and a user interface for operating the pipette, wherein the user interface comprises at least one touch screen for operating the pipetting operations of the pipette, which touch screen comprises at least one touching or pressing area for operating the pipetting operations of the pipette. The invention also relates to a method for operating an electronic pipette and a use of a touch screen as a part of a user interface of an electronic pipette for operating the pipetting operations of the pipette.

Description

CROSS-REFERENCE TO RELATED APPLICATIONS

The present application is a Continuation of U.S. Ser. No. 14/376,670, filed Aug. 5, 2014, which is a submission under 35 U.S.C. § 371 of International Application No. PCT/FI2013/050142, filed Feb. 8, 2013, which claims priority to Finnish Application No. 20125149, filed Feb. 13, 2012, the disclosures of which are hereby expressly incorporated by reference herein in their entireties.

FIELD OF THE INVENTION

The present invention relates to a pipette intended for use in the dosage of liquids and comprising an electronically operating control system with a user interface comprising an electronic display.

BACKGROUND OF THE INVENTION

Pipettes used for liquid dosage in laboratories comprise a piston movable in a cylinder for aspiration of liquid into a tip container connected with the cylinder. The volume is usually adjustable. There are also electronic pipettes whose piston is actuated by means of an electric motor and a control system associated with it. However, there are also electronic pipettes whose pistons are actuated by manual force and which comprise an electronic display only. Electronic pipettes have a user interface for selection of the desired pipette function (e.g., direct or reverse pipetting), setting of the volume and for giving commands for performing operations. The user interface has the necessary switches for input of the necessary settings and performance of the functions. The user interface is connected to a display, by means of which the volume and other necessary data can be displayed. The display can also show menus allowing data input in the control system.
Examples of known electronic pipettes are disclosed in International Publication Nos. WO 2005079989 and WO 2005079987, for example.
U.S. Pat. No. 8,033,188 discloses an electronic pipette, which comprises menu driven software for controlling the information displayed on the user interface display, for inputting information to program the pipettor and for controlling the operation of the pipettor. In this solution, the user interface also comprises a circular touch pad for navigating the user interface display and for operating the pipette.

SUMMARY OF THE INVENTION

An electronic controllable pipette in accordance with the present invention is equipped with one or more touch screens by which the pipetting operations of the pipette are operated.
The term “touch screen” within context of this description means an electronic visual display that displays information and that can detect the presence and location of a touch within the display area.
The touch screens may be used as modifiable function keys or buttons by which the pipetting operations of pipette are controlled. The touch screens may be equipped with pre-programmed icons for different operations of the pipette, whereby the icons define the active pressing areas of the touch screen for activating the related functions of the pipette. These icons may be moved to different places on the touch screen and/or on different touch screens of the pipette. The size of the icons, or the active area of the touch screen for receiving a touch to activate selected operation, may also be adjustable. Some areas of the touch screen or whole touch screen may also be adjusted to be inactive, so they may be used as support surfaces when operating the pipette.
Examples for pipetting operations to be covered with pre-programmable icons include ejecting the tip of the pipette, filling of the tip container, dispensing the tip container, and mixing action of the pipette, for example.
The touch screens may also be equipped with sliding functions, whereby, for example, the pipetting motion can be carried out by moving finger along the surface of the touch screen, which corresponds to a similar type of motion in manual pipettes. In this sliding function, the piston of the pipette follows the movement of the finger in real time. Alternatively, this sliding function can be used to activate pipette's mixing function, for example.
The touch screens of the electronic pipette in accordance with one embodiment of the present invention may also be curved, so that they may follow the curved surfaces of the pipette.
With an electronic pipette, in accordance with one embodiment of the present invention, it is possible to change locations of areas registering pressing or touching for operating the pipette to be suitable for different users and for different hands, thereby minimizing the stress caused to the hand when operating the pipette. The present invention also makes it possible to easily switch the locations of the pressing or touching areas, for example, for different fingers, during the use of the pipette, which makes it possible to minimize further the stresses caused by pipetting.
The electronic pipette, in accordance with one embodiment of the present invention, may also be equipped with a programmable feature for monitoring the physical stresses caused by the use of the pipette, and based on the monitoring, for suggesting modifications or changes to the placements of pressing or touching areas in order to lower the physical stresses. This programmable feature is advantageously part of the control software of the electronic pipette.
The present invention also allows a method for operating an electronic pipette, wherein the pipetting operations of the pipette are carried out by touching or pressing a touch screen, which touch screen is part of the user interface of the pipette.
Further, the present invention also allows a use of a touch screen as a part of a user interface of an electronic pipette for operating pipetting operations of the pipette.

BRIEF DESCRIPTION OF THE DRAWINGS

Exemplifying embodiments of the invention and its advantages are explained in greater detail below in the sense of an example and with reference to the accompanying drawings, where:

FIG. 1 shows an electronic pipette in accordance with one embodiment of the present invention,

FIG. 2 shows the main touch screen areas of the pipette of FIG. 1,

FIG. 3 shows a functional diagram of an electronic pipette in accordance with one embodiment of the present invention,

FIGS. 4A-4F show an example of operating an electronic pipette in accordance with one embodiment of the present invention,

FIGS. 5A-5E show an example of changing positions of operations in setting mode of an electronic pipette in accordance with one embodiment of the present invention, and

FIG. 6 shows examples of programmable icons for an electronic pipette in accordance with one embodiment of the present invention.

DETAILED DESCRIPTION OF THE INVENTION

FIG. 1 shows an example of an electronic pipette 1 in accordance with one embodiment of the present invention. When the pipette 1 is used, a tip container (not shown) is attached to the lower end 2 on the pipette. Inside the pipette 1 is located a piston movable in a cylinder in order to aspire liquid into the tip container. The piston of the pipette 1 is actuated by electric motor located within the pipette. The pipette 1 is operated with a control system that have a user interface comprising, in this example, three touch screens 3, 4 and 5.
During the use of the pipette 1, the pipette is gripped with hand from handle portion 6, which handle portion also comprises at its upper end a finger support 7. The touch screens 4 can be operated with the index finger of the gripping hand and the touch screens 3 and 5 can be operated with the thumb of the gripping hand. Alternatively, the touch screens 3, 4 and 5 can be operated with the fingers of the other hand.
As can be seen from FIG. 2, the touch screen 3 on the pipette 1 is divided to several areas 8-12 each of which can be set to either purely present information, register pressing or touching and carry out certain action, or combination of these two. Further, each of the areas 8-12, as well as the touch screens 4 and 5 or parts or these touch screens, can also be set to be inactive, for example, to be used as support surfaces.
Touch screens 3, 4 and 5 or parts of them can also be set to register sliding functions, whereby, for example, the pipetting motion can be carried out by moving finger along the surface of the touch screen. In this sliding function, the piston of the pipette follows the movement of the finger in real time. Alternatively, this sliding function can be used to activate pipette's mixing function, for example.
Touch screens 3, 4 and 5 also comprise pre-programmed icons for different pipetting operations, such as ejecting the tip of the pipette, filling of the tip container, dispensing the tip container, and mixing action of the pipette, for example. These icons advantageously identify the operation of the pressing or touching area as well as the active area related to this action.
FIG. 3 shows an example of a functional diagram of an electronic pipette, like the pipette 1 of FIG. 1. The operations of the pipette are controlled with a central processing unit (CPU), which is equipped with memory for storing pre-programmed operations and functions. The user gives commands to the CPU through touch screens A-D of which in this example there are four. The CPU is supplied with operating power by a battery and a voltage regulator, which can be recharged with a changer through charging connections when the pipette is placed in its stand. The CPU of the pipette can also be connected to external databases through data interface. The CPU receives information from and controls the pipette's piston reference position detector. In accordance with instructions received from the user through the touch screens A-D, the CPU controls the motor of the pipette through a motor driver. The dashed line on FIG. 3 presents boundary surface between the pipette itself and the stand of the pipette in which the pipette is placed when not in use.
FIGS. 4A-4F shows an example of operating an electronic pipette in accordance with one embodiment of the present invention. In this example, the touch screens of the pipette are used to change the pipetting volume.
In this operation, the user first touches the area of touch screen A showing the present pipetting volume, as shown in FIG. 4A. This action activates the touch screen A to change its view to a numeric touchpad, where the present pipetting volume (235 μl) is shown near the upper edge of the touch screen A over the numeric touchpad, and below the numeric touchpad is an area for a new pipetting volume. By touching the numbers of the numeric touchpad, the user inputs the new pipetting volume, as is shown in FIG. 4B. After correct new pipetting volume has been typed, the user accepts the new pipetting volume by touching the area showing the newly input pipetting volume, as shown in FIG. 4C. After the new pipetting volume is accepted, the touch screen A returns to the previous view where the pipetting volume has now changed to the new pipetting volume (73 μl), as shown in FIG. 4D. By touching or pressing the area of the touch pad A identified with word “FILL”, as shown in FIG. 4D, the user fills the tip of the pipette with set pipetting volume of 73 μl. Since the tip of the pipette now contains liquid, the area of the touch screen A, previously identified with word “FILL,” is changed to be identified with word “Dispense” by the control system of the pipette automatically and the operation activated by touching or pressing that area is changed correspondingly. Now, when the area with word “Dispense” is touched or pressed by the user, as is shown in FIG. 4E, the liquid volume of 73 μl, which previously was filled in the tip of the pipette, is dispensed from the tip of the pipette. In order to remove the used tip of the pipette, the user touches or presses a separate touch screen B, as shown in FIG. 4F, which touch screen B is set to activate the tip ejecting operation. The user is informed of this operation with the word “EJECT” located in the touch screen B.
FIGS. 5A-5E shows an example of changing positions of operations in setting mode of an electronic pipette in accordance with one embodiment of the present invention.
When pipette is in setting mode, the selected “EJECT” tab in touch screen B can be moved by activating it with a touch, as is shown in FIG. 5A. After activating the selected tab, it can then be moved out of the area of the touch screen B by moving finger along the touch screen B to the edge of the touch screen, as is shown in FIG. 5B. After the selected “EJECT” tab is moved out of the touch screen B, a touch screen where the tab is to be moved, in this case touch screen A, is activated by touching or pressing the touch screen, as is shown in FIG. 5C. Then the selected “EJECT” tab can be dragged to a selected location within touch screen A, as is shown in FIG. 5D. By releasing the tab, a new position for it within the touch screen B is set, as shown in FIG. 5E.
FIG. 6 shows examples with pre-programmable icons for operations of an electronic pipette in accordance with one embodiment of the present invention. As can be seen from the figure, these icons advantageously also contain clarifying words relating to the operations activated by touching the icon in question in the touch screen of the pipette.
While the present invention has been illustrated by description of various embodiments and while those embodiments have been described in considerable detail, it is not the intention of Applicants to restrict or in any way limit the scope of the appended claims to such details. Additional advantages and modifications will readily appear to those skilled in the art. The present invention in its broader aspects is therefore not limited to the specific details and illustrative examples shown and described. Accordingly, departures may be made from such details without departing from the spirit or scope of Applicants' invention.

Claims

What is claimed is:

1. A handheld electronic pipette, comprising:

a piston actuated in a cylinder by a motor,

a control system for carrying out pipette operations, and

a user interface provided on the pipette for operating the pipette,

wherein the user interface comprises at least one touch screen for operating the pipette operations of the pipette, which touch screen comprises at least one touching, pressing or sliding area for activating at least one of the following pipette operations of the pipette: ejecting a tip of the pipette, filling of a tip container, dispensing from a tip container, and mixing action of the pipette,

wherein touching, pressing or sliding of the at least one touching, pressing or sliding area activates driving of the motor for carrying out the pipette operation, and

wherein a size and/or a location of the at least one touching, pressing or sliding area within the at least one touch screen is adjustable by a user for different pipette operations.

2. The electronic pipette according to claim 1, wherein the user interface comprises 2-4 touch screens.

3. The electronic pipette according to claim 2, wherein the touching, pressing or sliding areas of different pipette operations are transferrable between different touch screens.

4. The electronic pipette according to claim 2, wherein the touching, pressing or sliding areas for different pipette operations within the touch screens are identifiable by pre-programmed icons.

5. The electronic pipette according to claim 1, wherein the at least one touch screen comprises sliding functions or operations that are operated by moving finger along the surface of the touch screen.

6. The electronic pipette according to claim 1, wherein some parts of the at least one touch screen are adjustable to be inactive.

7. The electronic pipette according to claim 1, wherein the user interface of the pipette comprises a programmable feature for monitoring the use of pipette operations and for suggesting modifications for locations of pressing, touching or sliding areas.

8. The electronic pipette according to claim 2, wherein at least some of the touch screens are curved and follow the curved surface of the pipette.

9. A method for operating a handheld electronic pipette having a user interface provided on the pipette, comprising:

driving a motor for carrying out pipette operations of the pipette by activating at least one of the following pipette operations of the pipette: ejecting a tip of the pipette, filling of a tip container, dispensing from a tip container, and mixing action of the pipette by touching, pressing or sliding an area of a touch screen, which touch screen is part of user interface of the pipette,

wherein a size and/or a location of the touching, pressing or sliding area within the touch screen is adjustable by the user for different pipette operations.

10. A handheld electronic pipette, comprising:

a piston actuated in a cylinder by a motor,

a control system for carrying out pipette operations, and

a user interface provided on the pipette for operating the pipette,

wherein touching, pressing or sliding of the at least one touching, pressing or sliding area activates driving of the motor for carrying out the pipette operation.