US20120220984A1 - Catheter Connection Systems - Google Patents

Catheter Connection Systems Download PDF

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Publication number
US20120220984A1
US20120220984A1 US13/469,849 US201213469849A US2012220984A1 US 20120220984 A1 US20120220984 A1 US 20120220984A1 US 201213469849 A US201213469849 A US 201213469849A US 2012220984 A1 US2012220984 A1 US 2012220984A1
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United States
Prior art keywords
sealing element
deformable sealing
connector system
catheter
retention collar
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Abandoned
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US13/469,849
Inventor
Mark A. Christensen
William R. Barron
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CR Bard Inc
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CR Bard Inc
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Application filed by CR Bard Inc filed Critical CR Bard Inc
Priority to US13/469,849 priority Critical patent/US20120220984A1/en
Publication of US20120220984A1 publication Critical patent/US20120220984A1/en
Abandoned legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • A61M25/0067Catheters; Hollow probes characterised by the distal end, e.g. tips
    • A61M25/0074Dynamic characteristics of the catheter tip, e.g. openable, closable, expandable or deformable
    • A61M25/0075Valve means
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M39/00Tubes, tube connectors, tube couplings, valves, access sites or the like, specially adapted for medical use
    • A61M39/10Tube connectors; Tube couplings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M39/00Tubes, tube connectors, tube couplings, valves, access sites or the like, specially adapted for medical use
    • A61M39/10Tube connectors; Tube couplings
    • A61M39/12Tube connectors; Tube couplings for joining a flexible tube to a rigid attachment
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M39/00Tubes, tube connectors, tube couplings, valves, access sites or the like, specially adapted for medical use
    • A61M39/22Valves or arrangement of valves
    • A61M39/26Valves closing automatically on disconnecting the line and opening on reconnection thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M39/00Tubes, tube connectors, tube couplings, valves, access sites or the like, specially adapted for medical use
    • A61M39/10Tube connectors; Tube couplings
    • A61M2039/1027Quick-acting type connectors

Definitions

  • Catheters may be employed for draining fluids from various organs or other locations within a patient.
  • catheters may be used for draining urine, a surgical wound, or any other body location that may be beneficial.
  • it may be desirable to selectively couple and decouple such a catheter to and from a drainage system or other system (e.g., aspiration system, cleansing system, etc.), respectively, for cleaning or for any other suitable reason.
  • a drainage system or other system e.g., aspiration system, cleansing system, etc.
  • Such a connection system can enable an increase in ambulation for the patient and thereby increase quality of life.
  • One aspect of the instant disclosure relates to a catheter connection system comprising at least two components and a deformable sealing element positioned between the at least two components configured to allow, upon deformation, fluid flow through the at least two components.
  • Another aspect of the instant disclosure relates to a catheter connection system comprising a sealing element positioned between at least two components, wherein the components are coupled to one another by a locking member.
  • FIG. 1 is a perspective view of one embodiment of a catheter coupling system
  • FIG. 2 is an exploded view of the catheter coupling system of FIG. 1 ;
  • FIG. 3 a is a side, cross-sectional view of the catheter coupling system shown in FIG. 1 ;
  • FIG. 3 b is a side, cross-sectional view of the catheter coupling system shown in FIG. 1 but with the catheter hub disconnected from the coupling member;
  • FIG. 4 is a perspective view of one embodiment of a seal post.
  • a catheter may include a connection structure for selectively coupling the catheter to another tubular element by way of a sealing element that forms a seal between the catheter and tubular element.
  • FIG. 1 includes a catheter connection system 10 comprising a catheter hub 20 , a coupling member 30 , and at least one deformable sealing element positioned within the catheter hub.
  • the deformable sealing element is configured to allow fluid flow through catheter hub 20 upon deformation.
  • the catheter connector system 10 comprises catheter hub 20 having a cannula 40 on a proximal end thereof sized for insertion into a lumen of a catheter 50 , and a housing 45 on a distal end thereof.
  • catheter hub 20 has a distal interface 60 having a seal post 70 positioned within a deformable sealing element 80 positioned further within a retention collar 90 .
  • the coupling member 30 includes a cavity 100 for receiving at least a portion of the distal interface 60 of catheter hub 20 and an actuating member 110 for engaging at least a portion of deformable sealing element 80 .
  • deformable sealing element 80 may abut seal post 70 to effectively seal a bore 115 of catheter hub 20 at one end.
  • deformable sealing element 80 creates a seal wherein any fluids attempting to pass through catheter hub 20 are precluded from movement past the seal.
  • deformable sealing element 80 deforms to a biased position 80 b thereby allowing fluid to flow through or by deformable sealing element 80 and into coupling member 30 .
  • deformable sealing element 80 reversibly returns to its unbiased position 80 a.
  • catheter hub 20 can further comprise an open space 120 between retention collar 90 and deformable sealing element 80 .
  • Open space 120 provides an area for deformable sealing element 80 to deform when it is engaged by coupling member 30 .
  • retention collar 90 may extend beyond deformable sealing element 80 and seal post 70 . Such a configuration may minimize inadvertent deformation of deformable sealing element 80 by a user.
  • actuating member 110 can be disposed concentrically within cavity 100 .
  • coupling member 30 can be configured with a through-center bore 130 for communicating a fluid from catheter hub 20 through coupling member 30 .
  • actuating member 110 comprises a raised surface located within cavity 100 of coupling member 30 .
  • the raised surface of actuating member 110 can be shaped to approximate the shape of deformable sealing element 80 such that when coupling member 30 and catheter hub 20 are secured together, as shown in FIG. 3 a , actuating member 110 deforms deformable sealing element 80 thereby allowing fluid to pass through catheter hub 20 and into coupling member 30 .
  • actuating member 110 may be configured to deform only a portion of deformable sealing element 80 .
  • seal post 70 may be positioned near deformable sealing element 80 to facilitate deformation of deformable sealing element 80 and passage of fluids through catheter hub 20 to coupling member 30 .
  • seal post 70 comprises a top planar surface 140 that, when seated in the body of catheter hub 20 and within the center of deformable sealing element 80 , creates a flush surface.
  • the body of seal post 70 can be tapered such that the diameter of a distal top planar surface 140 is larger than the diameter of the proximal end 150 of seal post 70 .
  • the body of seal post 70 can also comprise at least one channel 160 , wherein, when deformable sealing element 80 is deformed, fluid passes through channel 160 of seal post 70 and into coupling member 30 .
  • seal post 70 can be affixed (e.g., adhesively bonded, ultrasonically welded, solvent welded, or otherwise affixed) to the body of catheter hub 20 .
  • seal post 70 may be formed integrally or monolithically with the body of catheter hub 20 .
  • coupling member 30 and catheter hub 20 may be secured together with a locking member 180 .
  • the locking member 180 may be any device for securing catheter hub 20 and the coupling member 30 together, for example, a so-called “living hinge clip” or any cantilevered pivoting element.
  • FIGS. 1-3 b illustrate a coupling member 30 comprising a biased hinge member 190 integrally formed with the wall of coupling member 30 .
  • the hinge member 190 includes an engagement feature 200 configured to engage at least a portion of retention collar 90 of the body of catheter hub 20 .
  • handles 210 may be formed with hinge member 190 to facilitate removal and attachment of coupling member 30 .
  • the catheter connection system 10 may comprise an aperture 220 positioned on an outer portion of coupling member 30 .
  • aperture 220 allows the user to verify engagement of deformable sealing element 80 by actuating member 110 .
  • the catheter hub 20 also comprises a cover member 230 configured to reduce the likelihood of accidental removal of catheter 50 from cannula 40 of catheter hub 20 .
  • a proximal end of coupling member 30 may further comprise a luer fitting 240 configured to receive a device, for example, for vacuum assisted removal of fluids from the patient.
  • the proximal end of coupling member 30 may be configured for gravity evacuation of fluids from the patient.
  • the catheter hub 20 and coupling member 30 described above can be formed from any material suitable for connection to any elongated tubular member placed within the corpus of a patient.
  • the connector system 10 may be prepared from of any suitable thermo-plastically formed material.
  • the deformable sealing element 80 can be formed from a resilient material that is flexible, inert, and impermeable to fluid, such as silicone or polyurethane.
  • the above embodiments may be used, for example, in connection with a pleural drainage system.
  • a pleural drainage system One example of components of a pleural drainage system are disclosed in U.S. patent application Ser. No. 10/595,450 entitled “Portable Hand Pump for Evacuation of Fluids” which is incorporated herein in its entirety.
  • the present invention may be used to connect a catheter placed within the corpus of a patient for the purposes of evacuating fluid from the corpus of the patient to a manually-operated pump and a device for storage of the evacuated fluid.
  • the pump may be adapted to connect to an inflow conduit and an outflow conduit.
  • the pump, outflow conduit, and inflow conduit are all downstream from the connection system of the present invention.
  • the pump can be provided with a one-way inflow valve that acts to permit flow of fluids from the inflow conduit into the interior of the pump but limits or restricts any back flow of the same into the inflow conduit.
  • a one-way outflow valve permits flow of fluids out of the pump interior and into and through a lumen of the outflow conduit. This outflow one-way valve also serves to limit or restrict the back flow of fluids from the outflow conduit into the pump interior.

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  • Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Pulmonology (AREA)
  • Hematology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biophysics (AREA)
  • External Artificial Organs (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)

Abstract

A catheter connector system, including a catheter hub and a coupling member. The catheter hub includes a cannula portion connected to a housing portion and a distal interface including a tapered seal post fixed to the housing portion, a deformable sealing element surrounding the tapered seal post, and a retention collar surrounding the sealing element. The coupling member includes an opening to receive the distal interface, an inwardly extending portion to engage the retention collar, and an actuating member to engage the deformable sealing element.

Description

    PRIORITY
  • This application is a continuation of U.S. patent application Ser. No. 12/879,673, filed Sep. 10, 2010, which is a continuation of U.S. patent application Ser. No. 11/535,245, filed Sep. 26, 2006, now U.S. Pat. No. 8,177,772, which claims priority to U.S. Provisional Patent Application No. 60/720,443, filed Sep. 26, 2005, each of which is incorporated by reference into this application as if fully set forth herein.
  • BACKGROUND OF THE INVENTION
  • Catheters may be employed for draining fluids from various organs or other locations within a patient. For example, catheters may be used for draining urine, a surgical wound, or any other body location that may be beneficial. Further, it may be desirable to selectively couple and decouple such a catheter to and from a drainage system or other system (e.g., aspiration system, cleansing system, etc.), respectively, for cleaning or for any other suitable reason. Such a connection system can enable an increase in ambulation for the patient and thereby increase quality of life.
  • BRIEF SUMMARY
  • One aspect of the instant disclosure relates to a catheter connection system comprising at least two components and a deformable sealing element positioned between the at least two components configured to allow, upon deformation, fluid flow through the at least two components. Another aspect of the instant disclosure relates to a catheter connection system comprising a sealing element positioned between at least two components, wherein the components are coupled to one another by a locking member.
  • Features from any of the above-mentioned embodiments may be used in combination with one another in accordance with the instant disclosure. In addition, other features and advantages of the instant disclosure will become apparent to those of ordinary skill in the art through consideration of the ensuing description, the accompanying drawings, and the appended claims.
  • BRIEF DESCRIPTION OF THE DRAWINGS
  • Advantages of the present invention will become apparent upon review of the following detailed description and drawings, which illustrate representations (not necessarily drawn to scale) of various embodiments of the invention, wherein:
  • FIG. 1 is a perspective view of one embodiment of a catheter coupling system;
  • FIG. 2 is an exploded view of the catheter coupling system of FIG. 1;
  • FIG. 3 a is a side, cross-sectional view of the catheter coupling system shown in FIG. 1;
  • FIG. 3 b is a side, cross-sectional view of the catheter coupling system shown in FIG. 1 but with the catheter hub disconnected from the coupling member; and
  • FIG. 4 is a perspective view of one embodiment of a seal post.
  • DETAILED DESCRIPTION
  • One aspect of the instant disclosure relates to apparatuses and systems for selective coupling of a tubular member to another tubular element. Specifically, the instant disclosure contemplates that a catheter may include a connection structure for selectively coupling the catheter to another tubular element by way of a sealing element that forms a seal between the catheter and tubular element.
  • One aspect of the present invention, as shown in FIG. 1, includes a catheter connection system 10 comprising a catheter hub 20, a coupling member 30, and at least one deformable sealing element positioned within the catheter hub. The deformable sealing element is configured to allow fluid flow through catheter hub 20 upon deformation. As illustrated in FIG. 1 through 3 b, the catheter connector system 10 comprises catheter hub 20 having a cannula 40 on a proximal end thereof sized for insertion into a lumen of a catheter 50, and a housing 45 on a distal end thereof. Further, catheter hub 20 has a distal interface 60 having a seal post 70 positioned within a deformable sealing element 80 positioned further within a retention collar 90. As illustrated in FIG. 2, the coupling member 30 includes a cavity 100 for receiving at least a portion of the distal interface 60 of catheter hub 20 and an actuating member 110 for engaging at least a portion of deformable sealing element 80.
  • Referring now to FIGS. 3 a and 3 b, deformable sealing element 80 may abut seal post 70 to effectively seal a bore 115 of catheter hub 20 at one end. In an unbiased position 80 a, deformable sealing element 80 creates a seal wherein any fluids attempting to pass through catheter hub 20 are precluded from movement past the seal. When engaged by coupling member 30, deformable sealing element 80 deforms to a biased position 80 b thereby allowing fluid to flow through or by deformable sealing element 80 and into coupling member 30. When coupling member 30 is removed from catheter hub 20, deformable sealing element 80 reversibly returns to its unbiased position 80 a. The ability of deformable sealing element 80 to reversibly return to its unbiased position 80 a permits reuse of catheter hub 20. Furthermore, it advantageously creates a flush surface which facilitates cleaning of distal interface 60 of catheter hub 20. Referring now to FIGS. 3 a and 3 b, catheter hub 20 can further comprise an open space 120 between retention collar 90 and deformable sealing element 80. Open space 120 provides an area for deformable sealing element 80 to deform when it is engaged by coupling member 30. In one aspect of the invention, retention collar 90 may extend beyond deformable sealing element 80 and seal post 70. Such a configuration may minimize inadvertent deformation of deformable sealing element 80 by a user.
  • In one embodiment, actuating member 110 can be disposed concentrically within cavity 100. Further, coupling member 30 can be configured with a through-center bore 130 for communicating a fluid from catheter hub 20 through coupling member 30. In an additional embodiment, actuating member 110 comprises a raised surface located within cavity 100 of coupling member 30. The raised surface of actuating member 110 can be shaped to approximate the shape of deformable sealing element 80 such that when coupling member 30 and catheter hub 20 are secured together, as shown in FIG. 3 a, actuating member 110 deforms deformable sealing element 80 thereby allowing fluid to pass through catheter hub 20 and into coupling member 30. In another embodiment, actuating member 110 may be configured to deform only a portion of deformable sealing element 80.
  • In an additional embodiment, seal post 70 may be positioned near deformable sealing element 80 to facilitate deformation of deformable sealing element 80 and passage of fluids through catheter hub 20 to coupling member 30. In one embodiment, as shown in FIG. 4, seal post 70 comprises a top planar surface 140 that, when seated in the body of catheter hub 20 and within the center of deformable sealing element 80, creates a flush surface. The body of seal post 70 can be tapered such that the diameter of a distal top planar surface 140 is larger than the diameter of the proximal end 150 of seal post 70. The body of seal post 70 can also comprise at least one channel 160, wherein, when deformable sealing element 80 is deformed, fluid passes through channel 160 of seal post 70 and into coupling member 30. In such a configuration, seal post 70 can be affixed (e.g., adhesively bonded, ultrasonically welded, solvent welded, or otherwise affixed) to the body of catheter hub 20. In another embodiment, seal post 70 may be formed integrally or monolithically with the body of catheter hub 20.
  • In another embodiment of the present invention, coupling member 30 and catheter hub 20 may be secured together with a locking member 180. The locking member 180 may be any device for securing catheter hub 20 and the coupling member 30 together, for example, a so-called “living hinge clip” or any cantilevered pivoting element. FIGS. 1-3 b illustrate a coupling member 30 comprising a biased hinge member 190 integrally formed with the wall of coupling member 30. The hinge member 190 includes an engagement feature 200 configured to engage at least a portion of retention collar 90 of the body of catheter hub 20. Additionally, handles 210 may be formed with hinge member 190 to facilitate removal and attachment of coupling member 30. In one aspect of the invention, as shown in FIGS. 1 and 2, the catheter connection system 10 may comprise an aperture 220 positioned on an outer portion of coupling member 30. Advantageously, aperture 220 allows the user to verify engagement of deformable sealing element 80 by actuating member 110. In another embodiment, the catheter hub 20 also comprises a cover member 230 configured to reduce the likelihood of accidental removal of catheter 50 from cannula 40 of catheter hub 20. A proximal end of coupling member 30 may further comprise a luer fitting 240 configured to receive a device, for example, for vacuum assisted removal of fluids from the patient. In another embodiment, the proximal end of coupling member 30 may be configured for gravity evacuation of fluids from the patient.
  • The catheter hub 20 and coupling member 30 described above can be formed from any material suitable for connection to any elongated tubular member placed within the corpus of a patient. By way of example, the connector system 10 may be prepared from of any suitable thermo-plastically formed material. The deformable sealing element 80 can be formed from a resilient material that is flexible, inert, and impermeable to fluid, such as silicone or polyurethane.
  • The above embodiments may be used, for example, in connection with a pleural drainage system. One example of components of a pleural drainage system are disclosed in U.S. patent application Ser. No. 10/595,450 entitled “Portable Hand Pump for Evacuation of Fluids” which is incorporated herein in its entirety. More specifically, the present invention may be used to connect a catheter placed within the corpus of a patient for the purposes of evacuating fluid from the corpus of the patient to a manually-operated pump and a device for storage of the evacuated fluid. The pump may be adapted to connect to an inflow conduit and an outflow conduit. For purposes of clarity, the pump, outflow conduit, and inflow conduit are all downstream from the connection system of the present invention. Near the connection of the inflow conduit, the pump can be provided with a one-way inflow valve that acts to permit flow of fluids from the inflow conduit into the interior of the pump but limits or restricts any back flow of the same into the inflow conduit. Similarly, near the connection of the outflow conduit, a one-way outflow valve permits flow of fluids out of the pump interior and into and through a lumen of the outflow conduit. This outflow one-way valve also serves to limit or restrict the back flow of fluids from the outflow conduit into the pump interior.
  • While certain embodiments and details have been included herein for purposes of illustrating aspects of the instant disclosure, it will be apparent to those skilled in the art that various changes in the systems, apparatuses, and methods disclosed herein may be made without departing from the scope of the instant disclosure, which is defined, in part, in the appended claims. The words “including” and “having,” as used herein including the claims, shall have the same meaning as the word “comprising.”

Claims (13)

1. A catheter connector system, comprising:
a catheter hub, including:
a cannula portion connected to a housing portion, the cannula portion having an open end and a lumen in fluid communication therewith, and
a distal interface including a tapered seal post fixed to the housing portion, a deformable sealing element surrounding the tapered seal post, and a retention collar surrounding the sealing element; and
a coupling member, including:
an opening to receive the distal interface,
an inwardly extending portion to engage the retention collar, and
an actuating member to engage the deformable sealing element, the engagement of the retention collar by the inwardly extending portion maintaining engagement of the deformable sealing element by the actuating member.
2. The catheter connector system according to claim 1, wherein the deformable sealing element, the retention collar, and the actuating member are substantially annular.
3. The catheter connector system according to claim 1, comprising a sealed configuration wherein a sealing surface of the deformable sealing element is in contact with the seal post to prevent fluid flow through the catheter hub, and an open configuration where the deformable sealing element is deformed such that the sealing surface is longitudinally displaced with respect to the connector hub and the seal post to open a fluid flow path through the catheter hub.
4. The catheter connector system according to claim 1, wherein the tapered seal post, deformable sealing element, and retention collar extend beyond an end of the housing.
5. The catheter connector system according to claim 1, wherein a distal end of the tapered seal post, deformable sealing element, and retention collar are longitudinally co-extensive in a sealed position.
6. The catheter connector system according to claim 1, wherein the deformable sealing element is retained between the retention collar and the housing to longitudinally fix a proximal end of the deformable sealing element with respect to the catheter hub.
7. The catheter connector system according to claim 1, wherein the retention collar includes an internal indention creating an open space between the deformable sealing element and the retention collar to provide a volume for the deformable sealing element to deform when engaged by coupling member.
8. The catheter connector system according to claim 1, wherein the tapered seal post includes a plurality of longitudinal channels.
9. The catheter connector system according to claim 1, wherein the coupling member includes a cantilevered pivoting element associated with the inwardly extending portion to disengage the inwardly extending portion from the retention collar.
10. The catheter connector system according to claim 1, wherein the cantilevered pivoting element includes a handle.
11. The catheter connector system according to claim 1, wherein the coupling member includes an aperture to permit verification of engagement of the deformable sealing element by the actuating member when the inwardly extending portion is engaged with the retention collar.
12. The catheter connector system according to claim 1, further comprising a cover member surrounding the cannula portion.
13. The catheter connector system according to claim 1, wherein the coupling member includes a luer fitting.
US13/469,849 2005-09-26 2012-05-11 Catheter Connection Systems Abandoned US20120220984A1 (en)

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Application Number Priority Date Filing Date Title
US13/469,849 US20120220984A1 (en) 2005-09-26 2012-05-11 Catheter Connection Systems

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US72044305P 2005-09-26 2005-09-26
US11/535,245 US8177772B2 (en) 2005-09-26 2006-09-26 Catheter connection systems
US12/879,673 US8235971B2 (en) 2005-09-26 2010-09-10 Catheter connection systems
US13/469,849 US20120220984A1 (en) 2005-09-26 2012-05-11 Catheter Connection Systems

Related Parent Applications (1)

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US12/879,673 Continuation US8235971B2 (en) 2005-09-26 2010-09-10 Catheter connection systems

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US20120220984A1 true US20120220984A1 (en) 2012-08-30

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US11/535,245 Expired - Fee Related US8177772B2 (en) 2005-09-26 2006-09-26 Catheter connection systems
US12/879,673 Expired - Fee Related US8235971B2 (en) 2005-09-26 2010-09-10 Catheter connection systems
US13/469,849 Abandoned US20120220984A1 (en) 2005-09-26 2012-05-11 Catheter Connection Systems

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US12/879,673 Expired - Fee Related US8235971B2 (en) 2005-09-26 2010-09-10 Catheter connection systems

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US8177772B2 (en) 2012-05-15
US20070073270A1 (en) 2007-03-29
US20110009849A1 (en) 2011-01-13
US8235971B2 (en) 2012-08-07

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