US20120118782A1 - Blister package stiffening - Google Patents

Blister package stiffening Download PDF

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Publication number
US20120118782A1
US20120118782A1 US13/301,733 US201113301733A US2012118782A1 US 20120118782 A1 US20120118782 A1 US 20120118782A1 US 201113301733 A US201113301733 A US 201113301733A US 2012118782 A1 US2012118782 A1 US 2012118782A1
Authority
US
United States
Prior art keywords
windows
panel
sheet
blisters
blister
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
US13/301,733
Other languages
English (en)
Inventor
Gerard Stevens
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Manrex Pty Ltd
Original Assignee
Manrex Pty Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from AU2009202203A external-priority patent/AU2009202203A1/en
Priority claimed from PCT/AU2010/000623 external-priority patent/WO2010135765A1/fr
Application filed by Manrex Pty Ltd filed Critical Manrex Pty Ltd
Assigned to MANREX PTY. LTD. reassignment MANREX PTY. LTD. ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors: STEVENS, GERARD
Publication of US20120118782A1 publication Critical patent/US20120118782A1/en
Priority to PCT/AU2012/001339 priority Critical patent/WO2013075164A1/fr
Abandoned legal-status Critical Current

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Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D75/00—Packages comprising articles or materials partially or wholly enclosed in strips, sheets, blanks, tubes, or webs of flexible sheet material, e.g. in folded wrappers
    • B65D75/28—Articles or materials wholly enclosed in composite wrappers, i.e. wrappers formed by associating or interconnecting two or more sheets or blanks
    • B65D75/30—Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding
    • B65D75/32—Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding one or both sheets or blanks being recessed to accommodate contents
    • B65D75/325—Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding one or both sheets or blanks being recessed to accommodate contents one sheet being recessed, and the other being a flat not- rigid sheet, e.g. puncturable or peelable foil
    • B65D75/327—Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding one or both sheets or blanks being recessed to accommodate contents one sheet being recessed, and the other being a flat not- rigid sheet, e.g. puncturable or peelable foil and forming several compartments
    • B65D75/328—Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding one or both sheets or blanks being recessed to accommodate contents one sheet being recessed, and the other being a flat not- rigid sheet, e.g. puncturable or peelable foil and forming several compartments the compartments being interconnected, e.g. by small channels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/03—Containers specially adapted for medical or pharmaceutical purposes for pills or tablets
    • A61J1/035—Blister-type containers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D83/00—Containers or packages with special means for dispensing contents
    • B65D83/04—Containers or packages with special means for dispensing contents for dispensing annular, disc-shaped, or spherical or like small articles, e.g. tablets or pills
    • B65D83/0445—Containers or packages with special means for dispensing contents for dispensing annular, disc-shaped, or spherical or like small articles, e.g. tablets or pills all the articles being stored in individual compartments
    • B65D83/0463—Containers or packages with special means for dispensing contents for dispensing annular, disc-shaped, or spherical or like small articles, e.g. tablets or pills all the articles being stored in individual compartments formed in a band or a blisterweb, inserted in a dispensing device or container

Definitions

  • the subject matter of this application relates to blister package stiffening and, more particularly, relates to enhancing the stiffness of a blister package and is more specifically concerned with stiffening a blister package having sealed blisters between which air can pass by way of ducts extending between them.
  • a blister package containing the doses.
  • the package is constructed from a transparent blister sheet having blisters which individually contain the medication which the patient is required to take at a particular time on a particular day.
  • the medication doses are held in the blisters by a frangible backing sheet, such as a thin metal foil.
  • the blisters are transparent and have a relatively flexible front face so that finger pressure applied to the front face of a selected blister presses the doses inside it downwardly and against the backing sheet with sufficient force to cause the backing sheet to rupture. Such rupturing allows the doses to be released from the blister so that they can be collected for subsequent administration to the patient.
  • German published patent specification No. DE 3607012 A1 discloses in FIG. 9 a combination of bonded-together layers for altering the outline shape of a rectangular blister package so that it will fit within a holder side-by-side with other blister packages of the same rectangular outline.
  • the combination is created by several superimposed layers.
  • the first layer (designated 1′ in FIG. 9 of the German publication) comprises a blister sheet formed with as line of blisters (2) each of which has a separate tablet sealed within it.
  • the first layer has a rectangular outline but it is different from that required to fit side-by-side with other blister packages inside the holder.
  • the second layer (designated 11) comprises a preformed, rigid PVC deep-drawing foil formed with depressions which individually accommodate the blisters of the first layer. It also has the same rectangular outline shape as the first layer and is bonded to it.
  • the third layer is a carrier strip (designated 5) formed with a line of holes or cut-outs (7) through which the depressions of the second layer protrude.
  • the third layer is of the same rectangular outline as other blister packages which are to fit alongside it within the holder.
  • the surfaces of the third layer which are contiguous with the second layer are bonded to it and it is also formed with fingers arranged in opposed pairs and located between the holes. The purpose of these fingers are said to prevent the removal of one tablet from inadvertently rupturing the integrity of the neighboring sealed blister.
  • a fourth layer (not shown in FIG. 9) is a covering foil through which a tablet located in a depression may be pressed out by hand.
  • a blister package loaded with medication doses It is customary practice to stiffen and protect a blister package loaded with medication doses. This may be achieved by covering the exposed surface of the package from which the blisters protrude, with a stiff panel made of plastics, card or some other material which will enhance the stiffness of the package and which may also protect it from subsequent damage.
  • the panel may also be marked with legend to denote the times of day and the days of the week in which particular blisters are to be opened. Such marking cannot be easily carried out on the blister sheet itself.
  • an article of manufacture comprising a stiff planar sheet-form member for forming a stiffening panel, the sheet-form member being formed with cuts extending through its thickness and framing portions that, when removed, form an array of windows, whereby the stiffening panel that remains after removing said portions may be placed against lands on one face of a blister sheet with the windows receiving respective blisters of the blister sheet, and wherein the cuts extending through the thickness of the sheet-form member also form openings that communicate at opposite respective ends with respective windows, the openings being wider than they are long.
  • a planar stiffening panel for placing against lands on one face of a blister sheet from which blisters protrude, the panel being formed with an array of windows for receiving respective blisters of the blister sheet, and openings communicating at opposite respective ends with respective windows, and wherein the openings are wider than they are long.
  • blister package comprising a planar stiffening panel formed with cuts extending through its thickness and framing an array of windows, and a blister sheet having a major portion with first and second opposite faces and also having blisters protruding from the first face of the major portion, the major portion of the blister sheet having lands between adjacent blisters, wherein the blister sheet is positioned against the planar stiffening panel with the windows receiving the blisters and with portions of the stiffening panel in face-to-face contact with the lands of the blister sheet, the blister sheet includes at least one duct interconnecting two adjacent blisters, the stiffening panel has an opening that communicates at opposite respective ends with two adjacent windows that receive the two adjacent blisters respectively, and said opening accommodates the duct or ducts that interconnect said two adjacent blisters.
  • the windows are arranged in perpendicular columns and rows to provide a rectangular array of windows.
  • the windows are rectangular and the openings are formed between the shorter sides of the blisters flanking the two sides of the strip.
  • the face of the panel destined to lie flush against said one face of the blister package is covered with an adhesive layer protected by a flexible cover slip which can be manually peeled off the panel prior to panel being placed in its operating position against the blister package.
  • the cuts extending through the panel do not pass through the cover slip so that when it is peeled off, portions of the panel remain adhering to the cover slip to expose the windows and openings in the panel.
  • the panel may be made from stiff card or board or even plastic. Being planar it allows legend or other markings to be provided on its exposed face. As the panel can now lie flush against the sheet it can be firmly secured to it throughout its area. Contact between the panel and the sheet is thus uniform and not impaired in any way by the existence of the ducts extending between the blisters.
  • FIG. 1 shows in plan a rectangular stiff card providing a panel having one side covered by a pressure adhesive layer protected by a manually-removable flexible cover slip which can be peeled off to expose the adhesive layer, the card being formed with thin lines of severance provided by cuts which extend through the thickness of the card but do not extend through the slip;
  • FIG. 2 is a plan view of a stiffening panel as seen after the adhesive layer has been exposed by removal of the cover slip which takes with it adhering portions of the panel to expose the windows and openings;
  • FIG. 3 shows an unloaded blister sheet having a rectilinear array of blisters and formed with pairs of parallel ducts which open at their ends into the cavities of respective blisters;
  • FIG. 3A is a vertical section through part of FIG. 3 as indicated by, and in the direction of the arrows 3 A- 3 A in that figure;
  • FIG. 4 shows the combination of panel and blister sheet which is formed when the panel is pressed down to adhere onto coplanar lands of the blister sheet which extends around and between the blisters;
  • FIG. 4A is a vertical section through part of FIG. 4 as indicated by, and in the direction of the arrows 4 A- 4 A in that figure.
  • FIG. 1 shows a rectangular stiff card 1 backed by a layer of a pressure-sensitive adhesive (not shown) which is covered by a protective cover slip (also not shown).
  • the adhesive layer is pressure sensitive in the sense that when it is exposed to air by peeling off the slip, it will adhere to virtually any surface onto which it is pressed without being heated.
  • the card 1 is cut by slits extending through its thickness and defining closed outlines 3 which define separate portions 4 of the card which are not required.
  • the cover slip is peeled off the back of the card to expose the adhesive layer, the unwanted portions 4 of the card remain adhering to the cover slip and are removed with it.
  • the card then has the shape of the panel shown in FIG. 2 .
  • the removal of the separate portions 4 of the card leaves the panel with a rectangular array of windows 7 as shown in FIGS. 2 and 4 . These windows are approximately rectangular and are arranged in seven horizontal rows and four vertical columns.
  • Adjacent rows are mutually separated by strips 8 and the windows 7 in each row are partially separated from one another by pairs of opposed fingers 9 extending from the strips 8 to leave gaps 10 between their opposed ends.
  • One end portion of the panel (the lower end portion seen in FIGS. 1 and 2 ) has no windows 7 and provides a dedicated area for displaying personal details of a patient together with details of medication doses which a doctor has prescribed and which are to be contained in blisters 21 of a blister sheet 20 , shown in FIG. 3 .
  • the personal details and details of medication doses may be recorded on a self-adhesive label that is attached to the lower end portion of the panel.
  • the blister sheet 20 has its lands between the blisters attached to the panel by the adhesive layer on the back of the card. The blisters protrude individually through the windows 7 of the array as shown in FIG. 4 .
  • the opposite end portion 11 of the panel 16 (the upper end portion seen in FIGS. 1 and 2 ) is marked with a line 14 of small slits shown in FIG. 2 to facilitate its folding into two parts 15 and 16 which can be folded together beyond the end of the blister sheet 20 to bring two holes 13 on the parts into registration with one another. Slits extending between the registering holes enable the panel with an adhering blister sheet 20 to be easily suspended from hooks when not required.
  • the blister sheet 20 is shown in FIG. 3 prior to being loaded with prescribed medication doses. It will be apparent that the four blisters 21 of each row communicate with one another through a pair of narrow ducts 22 as shown in FIGS. 3 , 3 A, 4 , and 4 A.
  • the function of these ducts is to allow air to pass through them when one of the blisters is depressed by finger pressure so that its contents can be ejected through a frangible foil backing strip which adheres to the back of the panel.
  • the foil backing strip seals the cavities of the blisters after they have been loaded with medication doses.
  • the gap 10 should not have a length measured between two neighboring windows 7 greater than the distance separating a pair of opposed fingers 9 . If the length of the gap is greater than this distance, the resistance to air flow passing between neighboring blisters by way of the ducts will oppose the depression of a blister by finger pressure. It is also important that the duct wall is not salient with respect to the exposed surface of the card. The reason for this is that the pressure which must be applied to the surface of the lands of the card extending around and between the blisters must not result in the pressure also being applied to the external walls of the ducts. The effect of applying such pressure to the duct walls could be to reduce their internal cross-sectional area and thus impede the air flow through them during depression of a blister.
  • the optimum number of ducts is two extending in parallel to one another between neighboring blisters. To have more than two increases costs of tooling and increases the risk of damage to the ducts during the cold sealing process when pressure is applied to the card. Also the resistance to air flow through the ducts can increase rather than decrease, when a given cross-sectional area for air flow is provided by more than two ducts each of a smaller internal cross-sectional area than the ducts of a two-duct arrangement.

Landscapes

  • Mechanical Engineering (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Composite Materials (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Packages (AREA)
  • Buffer Packaging (AREA)
US13/301,733 2009-05-28 2011-11-21 Blister package stiffening Abandoned US20120118782A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
PCT/AU2012/001339 WO2013075164A1 (fr) 2011-11-21 2012-11-02 Renforcement de blister

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
AU2009202203A AU2009202203A1 (en) 2000-12-28 2009-05-28 Blister with Tilting Side-Walls
AU2009100522A AU2009100522A4 (en) 2009-05-28 2009-05-28 Blister Package Stiffening
AU2009202203 2009-05-28
AU2009100522 2009-05-28
PCT/AU2010/000623 WO2010135765A1 (fr) 2009-05-28 2010-05-24 Emballage-coque avec parois latérales à inclinaison
PCT/AU2010/000624 WO2010135766A1 (fr) 2009-05-28 2010-05-24 Rigidification d'emballage-coque

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
PCT/AU2010/000624 Continuation-In-Part WO2010135766A1 (fr) 2009-05-28 2010-05-24 Rigidification d'emballage-coque

Publications (1)

Publication Number Publication Date
US20120118782A1 true US20120118782A1 (en) 2012-05-17

Family

ID=40943465

Family Applications (1)

Application Number Title Priority Date Filing Date
US13/301,733 Abandoned US20120118782A1 (en) 2009-05-28 2011-11-21 Blister package stiffening

Country Status (9)

Country Link
US (1) US20120118782A1 (fr)
EP (1) EP2435334B1 (fr)
CN (1) CN102448845B (fr)
AU (2) AU2009100522A4 (fr)
CA (1) CA2763060C (fr)
ES (1) ES2536550T3 (fr)
HK (1) HK1168335A1 (fr)
MY (1) MY159617A (fr)
WO (1) WO2010135766A1 (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2013075164A1 (fr) * 2011-11-21 2013-05-30 Manrex Pty, Ltd. Renforcement de blister

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3054503A (en) * 1961-04-06 1962-09-18 Sparks Corp Push-out-blister package
US4753352A (en) * 1986-01-22 1988-06-28 Adir Et Compagnie Impervious packaging in the form of a card having compartments and permitting gaseous exchange between the compartments

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3607012A1 (de) * 1986-03-04 1987-09-10 Eurim Pharm Arzneimittel Gmbh Einlagestreifen fuer aufnahmeschachteln von tabletten oder dgl.
CN2159944Y (zh) * 1993-07-19 1994-03-30 太原铁路分局太原铁路中心医院 硝酸甘油片新型包装袋
CH687615A5 (de) * 1994-09-07 1997-01-15 R W Johnson Pharmaceutical Res Tropen-Verpackung.
JP4179912B2 (ja) * 2003-03-31 2008-11-12 朝日印刷株式会社 Ｐｔｐシート用包装体
US7624872B2 (en) * 2003-09-09 2009-12-01 Future Technology (R&D) Ltd. Low vapour transmission dispensing container and cover film employed therewith
WO2007141869A1 (fr) * 2006-06-02 2007-12-13 Fujimurakougyou Co, Ltd. Dispositif d'ouverture de contenant de conditionnement

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3054503A (en) * 1961-04-06 1962-09-18 Sparks Corp Push-out-blister package
US4753352A (en) * 1986-01-22 1988-06-28 Adir Et Compagnie Impervious packaging in the form of a card having compartments and permitting gaseous exchange between the compartments

Also Published As

Publication number Publication date
EP2435334A4 (fr) 2014-01-15
AU2010251865A1 (en) 2011-11-03
EP2435334B1 (fr) 2015-03-18
CA2763060C (fr) 2015-05-12
HK1168335A1 (en) 2012-12-28
AU2010251865B2 (en) 2015-11-05
AU2009100522A4 (en) 2009-08-06
WO2010135766A1 (fr) 2010-12-02
ES2536550T3 (es) 2015-05-26
CA2763060A1 (fr) 2010-12-02
MY159617A (en) 2017-01-13
CN102448845A (zh) 2012-05-09
EP2435334A1 (fr) 2012-04-04
CN102448845B (zh) 2014-02-19

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Legal Events

Date Code Title Description
AS Assignment

Owner name: MANREX PTY. LTD., AUSTRALIA

Free format text: ASSIGNMENT OF ASSIGNORS INTEREST;ASSIGNOR:STEVENS, GERARD;REEL/FRAME:027613/0022

Effective date: 20120113

STCB Information on status: application discontinuation

Free format text: ABANDONED -- FAILURE TO RESPOND TO AN OFFICE ACTION