US20100211057A1 - Tissue heating device and rf heating method with tissue attachment feature - Google Patents

Tissue heating device and rf heating method with tissue attachment feature Download PDF

Info

Publication number
US20100211057A1
US20100211057A1 US12768587 US76858710A US2010211057A1 US 20100211057 A1 US20100211057 A1 US 20100211057A1 US 12768587 US12768587 US 12768587 US 76858710 A US76858710 A US 76858710A US 2010211057 A1 US2010211057 A1 US 2010211057A1
Authority
US
Grant status
Application
Patent type
Prior art keywords
cutting
catheter
tissue
cartridge
element
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
US12768587
Inventor
Russell A. Houser
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cardio Vascular Tech Inc a California Corp
Original Assignee
Cardio Vascular Tech Inc a California Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date

Links

Images

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/04Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
    • A61B18/12Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
    • A61B18/14Probes or electrodes therefor
    • A61B18/1492Probes or electrodes therefor having a flexible, catheter-like structure, e.g. for heart ablation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00571Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body for achieving a particular surgical effect
    • A61B2018/00601Cutting
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/18Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves
    • A61B18/1815Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using microwaves
    • A61B2018/1861Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using microwaves with an instrument inserted into a body lumen or cavity, e.g. a catheter
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2218/00Details of surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2218/001Details of surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body having means for irrigation and/or aspiration of substances to and/or from the surgical site
    • A61B2218/007Aspiration

Abstract

A tissue cutting device includes a catheter with a window at its distal tip for admitting tissue into a catheter compartment. A cylindrical cartridge in the compartment has a cutting edge that supports an electrically conductive cutting element, e.g. a band or wire. The cutting element and adjacent tissue can be heated to a selected temperature by generating an electrical current through the cutting element. The catheter is maneuverable to position its distal end near the tissue to be cut. The catheter incorporates a dilatation balloon or other feature to urge the catheter against the tissue, so that at least part of the tissue may enter the compartment through the window. Then, the cartridge is manipulated from the catheter's proximal end to move the cutting edge across the window, cutting the tissue. According to alternative embodiments, the cartridge is either rotated or moved axially relative to the catheter and, in either event may be capable of closing the catheter window when the cut is complete. Further alternatives involve either placing an indifferent electrode on the patient and providing an RF signal via a single conductor to the cutting element for ohmic heating, or providing an RF (or a DC) current through the cutting element and two separate conductors for direct resistive heating of the cutting element.

Description

    CROSS-REFERENCE
  • [0001]
    This application is a continuation application of Ser. No. 11/671,723 filed Feb. 6, 2007, which is a continuation application of Ser. No. 10/906,164 filed on Feb. 4, 2005, now U.S. Pat. No. 7,172,590, which is a continuation application of Ser. No. 10/404,720 filed on Apr. 1, 2003, now U.S. Pat. No. 6,872,204, which is a divisional application of Ser. No. 09/804,009 filed Mar. 12, 2001, now U.S. Pat. No. 6,540,761 which is a divisional application of Ser. No. 09/256,020, filed Feb. 23, 1999, now U.S. Pat. No. 6,214,024 which is a divisional application of Ser. No. 08/899,490 filed on Jul. 19, 1997, now U.S. Pat. No. 5,876,369, and a divisional application of Ser. No. 08/376,226 filed on Jan. 23, 1995, now U.S. Pat. No. 5,665,062.
  • BACKGROUND OF THE INVENTION
  • [0002]
    The present invention relates to devices for removing obstructions from body lumens, and more particularly to catheters for removing atherosclerotic plaque and thrombotic occlusions from blood vessels.
  • [0003]
    Atherectomy catheters are known for their utility in removing atherosclerotic plaque and thrombotic occlusions from arteries. While intended mainly for use in the coronary arteries, such catheters may as well be used in peripheral vessels. Beyond coronary uses, such catheters can have neurological applications, e.g. removal of lesions in carotid arteries, gynecological use in re-canalizing fallopian tubes, and a potential urological application for removal of benign prostate hyperplasia.
  • [0004]
    Atherectomy catheters have a variety of designs. According to one design, the catheter has a rounded or bullet shaped tip with an abrasive surface. At the treatment site, the tip is rotated at high speed and burrows through the occlusion. The resulting debris, typically in particulate form, is not captured by the device. Rather, it is allowed to flow to the capillary bed where it is absorbed. The device is most effective in abrading hardened (calcified) occlusions, with the intent being to produce particulate debris no larger than about 7 microns in diameter. When encountering softer occlusions, however, the device presents the risk of an occlusion breaking off during the atherectomy procedure, causing an acute and potentially life-threatening reclosure of the artery. The abrasive tip may inadvertently remove endothelium cells during catheter insertion, use or removal, thereby creating sites for potential lesions.
  • [0005]
    A second type of catheter employs a cartridge housed within the catheter, near the catheter distal tip. When the distal tip region is placed near the occlusion, plaque enters the cartridge through an opening or “cutting window”. A cup-shaped blade then is rotated or oscillated at high speed, and advanced to cut and capture plaque that entered the cartridge. U.S. Pat. No. 5,312,425 (Evans); U.S. Pat. No. 5,087,265 (Summers); and U.S. Pat. No. 5,085,662 (Willard) disclose versions of atherectomy catheters with a movable blade or cartridge within a tissue collection volume near the catheter distal tip.
  • [0006]
    An example of an atherectomy catheter that depends on vaporization of plaque is found in U.S. Pat. No. 5,087,256 (Taylor). A dome-shaped head on the tip can be heated to temperatures in the range of 300 400 degrees C., for disintegrating plaque. U.S. Pat. No. 5,098,431 (Rydell) discloses a catheter in which an RF discharge between two spaced apart annular electrodes, electrosurgically cuts tissue to remove a blockage.
  • [0007]
    Conventional atherectomy catheters are limited principally to an axial cutting direction and subject to smooth cell muscle migration (restonosis) after treatment. Patients treated with conventional atherectomy devices have restonosis rates of 30 40 percent within the six months following treatment.
  • [0008]
    Therefore, it is an object of the present invention to provide an atherectomy catheter with a cutting edge that achieves a finer, more accurate cutting of unwanted tissue, to reduce the risk of acute blockage due to the breaking off of an occlusion.
  • [0009]
    Another object is to provide a tissue cutting element for an atherectomy catheter that is effective in severing calcified and soft occlusions.
  • [0010]
    A further object is to provide a flexible atherectomy catheter that incorporates means for capturing tissue being severed, to ensure against the escape of such tissue into the blood stream.
  • [0011]
    Yet another object is to provide an atherectomy catheter with enhanced versatility, due to the incorporation of longitudinal and transverse (arcuate) tissue cutting motions.
  • [0012]
    Further, it is an object of the present invention to provide an atherectomy catheter and procedure tending to seal the region of the cut, thus tending to reduce the incidence of restonosis.
  • SUMMARY OF THE INVENTION
  • [0013]
    To achieve these and other objects, there is provided a device for removing atheromas from a body lumen. The device includes an elongate catheter having a proximal end and a distal end. The catheter has a wall that defines a compartment within the catheter near its distal end, and a window is formed through the catheter wall to allow entry into the compartment. The catheter incorporates an electrically conductive tissue cutting element. A means is provided for generating an electrical current in the cutting element to heat the cutting element and adjacent tissue at least to a selected temperature above normal body temperature (i.e. 37 degrees C.). A carrier is mounted movably relative to the catheter, for supporting the cutting element proximate the window and for a controlled movement of the cutting element along and adjacent the window. The catheter is flexible and maneuverable to locate its distal tip within a body lumen and to place the window against a tissue wall segment of the body lumen to acquire tissue within the compartment. The cutting element, when heated and when undergoing the controlled movement, severs the acquired tissue.
  • [0014]
    There are several suitable approaches for generating the current necessary for cutting. At present, the most preferred approach involves a biocompatible cutting element (e.g. of platinum) subjected to RF energy in combination with an indifferent plate electrode on the patient's back. Application of the RF energy causes ohmic heating of tissue near the cutting element as current passes through the tissue.
  • [0015]
    As an alternative, RF energy can be applied to heat an electrically resistive cutting element formed of nickel or a nickel chromium alloy. In this approach, the cutting element is heated to a temperature sufficient to sever a lesion that comes into contact with the element. As a third and presently least preferred alternative, DC power is applied to heat an electrically resistive cutting element, again of nickel or a nickel chromium alloy. For biocompatibility, an insulative jacket or coating is applied to the nickel or nickel chromium cutting element.
  • [0016]
    The preferred cutting element is a flat band, having a thickness of about 0.015 inches and a substantially greater width. The band achieves a highly accurate and fine cut of the tissue, considerably reducing the pulling and tearing of tissue as compared to the conventional oscillating or rotating blades. Unwanted tissue is severed more cleanly, reducing patient risk. Further, it is believed that the elevated temperatures of the band and adjacent tissue have a sealing or cauterizing effect along the region of the cut. This is believed to result in a substantial reduction in restenosis in the treated artery.
  • [0017]
    As an alternative to a flat band, the cutting element can be a fine wire having a diameter of about 0.030 inches or less to provide the cutting edge.
  • [0018]
    The carrier preferably includes a cartridge contained within the compartment. The cartridge can have an axially extended cartridge wall, a cartridge opening and a cutting edge along the cartridge opening for supporting the cutting element. A control means is coupled to the cartridge proximal end, and operable to selectively position and move the cartridge within the compartment, to provide the controlled movement of the cutting element. Preferably the cartridge wall is longer axially than the window, so that the cartridge can be positioned to substantially close the window and thus capture severed tissue. With tissue secured in this manner, there is no need for a suction device or other means to withdraw tissue proximally through the catheter immediately after it is cut. With no need to pay attention to a vacuum or suction means, the physician is able to direct more attention to the atherectomy procedure at hand.
  • [0019]
    Conversely, a vacuum means (or alternatively a plunger device and a diaphragm valve) may be provided if desired for removing severed tissue from the compartment, to allow cutting and removal of tissue at several locations during a single procedure.
  • [0020]
    There are several alternatives for supporting the cutting element. For example, the cutting edge can be the leading or distal edge of the cartridge, preferably but not necessarily annular. In this event, the cartridge is moved distally to provide the necessary controlled movement of the cutting element. Alternatively, the cutting edge can be an axial edge of the cartridge opening, in which event the cartridge is rotated about a longitudinal axis to move the cutting element in an arcuate path.
  • [0021]
    A preferred control means includes an elongate drive member, e.g. a rod, coil or tube, attached to the proximal end of the cartridge and extending proximally to a proximal end of the catheter. The member can be rotated, pushed or pulled at the catheter proximal end, to impart like motion to the cartridge.
  • [0022]
    Another aspect of the invention is a process for removing tissue from a body lumen, according to the following steps:
  • [0023]
    a. providing, near a distal end of an elongate catheter, a compartment and a window to the compartment through a catheter wall, and an electrically conductive tissue cutting element mounted to the catheter for a controlled movement of the cutting element adjacent and along the window;
  • [0024]
    b. inserting the catheter into a body lumen, and guiding the catheter to position the window against a tissue wall segment of the body lumen, thus to cause tissue to enter the compartment via the window and occupy the compartment;
  • [0025]
    c. generating an electrical current in the cutting element to heat the cutting element and adjacent tissue at least to a selected temperature above normal body temperature, while causing the cutting element to undergo the controlled movement, thereby to sever the tissue occupying the compartment.
  • [0026]
    After the tissue is severed, the compartment can be closed to prevent egress of the severed tissue. The controlled movement of the cutting element can be one of two alternatives: substantially linear and axial with respect to the catheter, or arcuate about an axis running longitudinally of the catheter.
  • [0027]
    Thus in accordance with the present invention, there is provided an atherectomy device and procedure suitable for treating soft occlusions and calcified occlusions alike, with clean and accurate cutting that reduces the risk of tissue tearing and escaping into the blood vessel under treatment. The catheter is versatile, due to its flexibility for traversing tortuous vessels and for the ability to cut in either an arcuate or axial path. The application of heat is concentrated along the region of the cut, i.e. the cutting element and adjacent tissue, reducing the required cutting force, increasing cutting accuracy and tending to cauterize or seal the region of the cut, thus tending to substantially prevent restonosis.
  • BRIEF DESCRIPTION OF THE DRAWINGS
  • [0028]
    For a further understanding of the above features and advantages, reference is made to the following detailed description and to the drawings, in which:
  • [0029]
    FIG. 1 is an elevation of an atherectomy device constructed in accordance with the present invention;
  • [0030]
    FIG. 2 is a sectional view taken along the line 2-2 in FIG. 1;
  • [0031]
    FIGS. 3 and 4 are sectional views taken along the lines 3-3 in FIG. 1 and 4-4 in FIG. 2;
  • [0032]
    FIG. 5 is a perspective view of a tissue retaining cartridge employed in the device;
  • [0033]
    FIG. 6 is a schematic view illustrating circuitry for providing an electrical current through a mounted heating element on the cartridge;
  • [0034]
    FIGS. 7 9 are diagrammatic views illustrating use of the device;
  • [0035]
    FIG. 10 is an elevational view of the distal end region of an alternative atherectomy device constructed according to the invention;
  • [0036]
    FIG. 11 is a sectional view taken along the line 11-11 in FIG. 10;
  • [0037]
    FIG. 12 is a perspective view of a tissue retaining cartridge used in the device of FIG. 10;
  • [0038]
    FIGS. 13 and 14 diagrammatically illustrate use of the device of FIG. 9;
  • [0039]
    FIG. 15 is a three-dimensional illustration of an alternative embodiment cartridge; and
  • [0040]
    FIG. 16 is a schematic view of an alternative circuit for heating the cutting element.
  • DETAILED DESCRIPTION OF THE INVENTION
  • [0041]
    Turning now to the drawings, there is shown in FIG. 1 an atherectomy device 16 for removing unwanted tissue from body lumens, more particularly blood vessels. The device includes a control housing or handle 18, and an elongate and pliable catheter 20 connected at its proximal end to the handle.
  • [0042]
    Catheter 20 is formed of a biocompatible polymer such as Pebax® polyether block amides, Pellethane® polyurethane or polyimide, and can have an outside diameter in the range of 3 Fr. (1 mm) to 8 Fr. (2.7 mm) or larger. Catheter 20 includes several lumens that run axially from handle 18 to a distal end region 22. A guidewire 24, contained within one of the lumens, extends proximally beyond handle 18 and distally beyond a tapered distal tip 26 of the catheter. Further lumens are provided in the catheter, for delivery of contrast fluid or treatment fluid to the distal end region, and for balloon inflation. While not shown, a braided or other filament structure can be embedded into the catheter body to enhance torque transmission, if desired.
  • [0043]
    A window 28 is formed through a wall 30 of the catheter along the distal end region. Window 28 is elongate in the axial direction and extends along about forty percent of the circumference of catheter wall 30. A cartridge or cutting sleeve 32 is contained within catheter 20. The cartridge is shown adjacent and along window 28, but is movable axially relative to the catheter. This enables a proximal retraction of the cartridge from window 28, to open the window whereby the catheter can acquire tissue. An elongate drive rod 34, contained within a lumen of catheter 20, is coupled to the proximal end of cartridge 32 and extends proximally through the catheter and into handle 18.
  • [0044]
    Drive rod 34 is formed of an electrically insulative material, e.g. a PTFE coated wire coil or spiral wrapped polyimide. The drive rod has a high degree of bending elasticity to permit its movement (with the remainder of catheter 20) along serpentine passages toward an intended treatment site. At the same time, drive rod 34 is sufficiently rigid in the axial direction to permit controlling the cartridge axial position by manipulating the drive rod at its proximal end. Drive rod 34 is constructed of an electrically insulated material. A pair of conductors 36 and 38, preferably polyimide jacketed copper or copper-clad steel wires, are bonded to the drive rod and electrically isolated from one another. Conductors 36 and 38 extend along the entire catheter length to control housing 18.
  • [0045]
    A dilatation balloon 40 is formed to extend axially along distal end region 22, axially aligned with window 28 but also spaced apart angularly 180 degrees, i.e. on the opposite side of the catheter from the window. Balloon 40 is inflated using a fluid supplied to the balloon under pressure via a lumen of catheter 20.
  • [0046]
    A fluid port 42 admits contrast or treatment fluids in the region just proximally of window 28, while such fluids can be administered distally of the window via the guidewire lumen.
  • [0047]
    Control housing 18 includes three branches for coupling two sources of fluid (not shown): a branch 44 for balloon inflation, and two branches 46 and 48 for delivery of contrast fluids or treatment fluids such as heparin. At the proximal end of the control housing is a connector 50 with two electrically independent paths coupled to conductors 36 and 38, respectively. A line 52 (e.g. coaxial) removably electrically couples connector 50 to a power supply 54. Power supply 54 preferably is an RF source, but can be a DC source as well. Also mounted at the housing proximal end are a fitting 56 and a control knob 58. Knob 58, coupled to the proximal end of drive rod 34, is movable axially relative to fitting 56, to control the axial position of cartridge 32.
  • [0048]
    A display 60 (e.g. LED) indicates the temperature of a cutting element mounted to the cartridge. A temperature control 62 adjusts the current through the cutting element, thus to set the cutting element temperature.
  • [0049]
    FIG. 2 shows several lumens running through the catheter, including a guidewire lumen 64 that also can be used to administer contrast and treatment fluids. A control lumen 66 accommodates drive rod 34. Further lumens include a balloon inflation lumen 68 and an upper infusion lumen 70 for providing fluids to fluid port 42.
  • [0050]
    As seen in FIGS. 3 and 4, control lumen 66 along the distal end region forms a compartment 72 to accommodate cartridge 32. The compartment extends distally beyond window 28 a slight distance, and extends proximally of the window a sufficient amount to allow cartridge retraction, i.e. placing the complete cartridge proximally of the window.
  • [0051]
    Cartridge 32 is cylindrical, having an axial wall 74 and a disk-shaped proximal wall 76. As seen in FIG. 5, cartridge 32 is open at its distal end to provide a circular cutting edge 78. A tissue cut element, more particularly a fine, flat band 80, is mounted to the cutting edge to form an arc. Band 80 need not circumscribe the cutting edge, but should extend a sufficient amount to span window 28. Band 80 has a thickness of about 0.015 inches, and is formed of nickel or a nickel chromium alloy coated for biocompatibility. Alternatively (in an indifferent electrode approach discussed below) the band can be formed of platinum or another electrically conductive and body compatible material. The band is heated when subject to an electrical current. As an alternative to the band, the cutting element can be a wire with a diameter of at most 0.030 inches.
  • [0052]
    The polymer forming cartridge 32 can be blended with barium sulphate, bismuth trioxide or another suitable radiopaque material to facilitate fluoroscopic observation of the cartridge position before and during tissue removal. Radiopaque markers also may be placed along the cartridge cutting edge and on corresponding (distal and proximal, or intermediate) edges of the window. Along with aiding accurate positioning, these markers are useful in confirming when the cartridge is closed after cutting.
  • [0053]
    Conductors 36 and 38 are coupled to opposite ends of cutting element 80. As indicated in broken lines, conductors 36 and 38 are embedded in axial wall 74 which, like the drive rod, is electrically insulative. A thermocouple 82 can be mounted to the cartridge near cutting edge 78 and preferably bonded to cutting element 80, to monitor the cutting element temperature. Conductors 84, embedded in the cartridge and the drive rod, permit the cutting element temperature to be monitored from control housing 18. Alternatively, thermistors can be used to sense temperature. Further, for a resistive cutting element (i.e. nickel or nickel chromium) a characteristic dependence of resistance upon temperature can be used to monitor the cutting element temperature.
  • [0054]
    Tissue is cut by advancing cartridge 32 distally from the retracted position, with cutting element 80 and adjacent tissue maintained at least a predetermined temperature above body temperature. A circuit for heating the cutting element and tissue is schematically illustrated in FIG. 6. A controller 86 adjusts power from supply 54 as required, for generating current through cutting element 80 in an amount selected to heat the cutting element to the predetermined temperature. Thermocouple 82 senses the temperature and provides the corresponding temperature reading at display 60. If the display indicates a need to increase or reduce the temperature, controller 86 is adjusted to alter the current accordingly. A broken line at 88 indicates that if desired, the output of thermocouple 82 can be employed to automatically adjust the cutting element current.
  • [0055]
    The use of device 16 to remove unwanted tissue is shown in FIGS. 7 9, where catheter 20 has been either steered or moved over guidewire 24 to a treatment position near a lesion 90 in a coronary artery. Catheter 20 is manipulated from housing 18 to axially and angularly align the catheter and lesion 90, so that window 28 faces the lesion (FIG. 7). At this point, dilatation fluid is supplied to expand balloon 40 against an arterial wall 92 opposite the lesion (e.g. as in aforementioned U.S. Pat. No. 5,085,662). Balloon dilatation drives the catheter distal end upward as viewed in FIGS. 7 9, forcing the catheter against the arterial wall about lesion 90 and causing at least a portion of the lesion to enter compartment 72 through window 28.
  • [0056]
    With tissue thus acquired, cartridge 32 is advanced distally from the retracted position, while cutting element 80 is maintained at the selected temperature, from 50 600 degrees C. and more preferably 50 400 degrees C. This heating of the wire and adjacent tissue considerably enhances the cutting of tissue. Moreover, the heating has a cauterizing effect at the region of the cut and thus tends to seal the wound almost immediately after cutting, to significantly reduce smooth cell muscle migration or restenosis after treatment. The minute filament results in a precise, well defined cutting path that minimizes stretching and tearing of tissue. Accordingly, cutting element is effective in severing soft tissue as well as calcified or hardened tissue. This minimizes the risk of tissue fragmenting into particles or pieces that escape into the bloodstream.
  • [0057]
    Cartridge 32 is advanced until cutting edge 78 is distally of window 28 (FIG. 9), to completely acquire severed tissue within the cartridge. During or following the cut, a treatment fluid may be administered through lumens 64 and 70. After balloon deflation, the cartridge can be proximally withdrawn to remove the severed tissue.
  • [0058]
    In addition to the cauterizing/sealing effect, a salient feature of the invention is the continuity of axial wall 74, which closes window 28 when the cartridge is completely advanced. This insures that severed tissue remains captured within compartment 72 as the catheter is withdrawn, thus to eliminate the risk that severed tissue will enter the bloodstream.
  • [0059]
    FIG. 10 illustrates, in axial (longitudinal) section, the distal end region of an alternative device 96. This device differs from device 16 in several respects concerning primarily the catheter distal end, but also as to the manner of controlling the cartridge. A catheter 98 of device 96 has flexible band 100 along its distal end in lieu of a dilatation balloon. Band 100 can be flexed radially away from the catheter and, upon contacting an artery, drives the catheter toward the opposite end of the artery. An example of such band and its control is found in U.S. Pat. No. 5,087,265 (Summers).
  • [0060]
    A single, central lumen 102 accommodates the guidewire and is enlarged to provide a compartment 104. The compartment accommodates a cartridge 106 having an axially extended wall 108, a proximal end wall 110 and a distal end wall 112. A drive tube 114, connected to the proximal end wall, is manipulated at the housing to selectively position cartridge 106.
  • [0061]
    Drive tube 114 is used to rotate cartridge 106 about a longitudinal axis, rather than to move the cartridge axially. Consequently, while it requires less axial stiffness than drive rod 34, drive tube 114 must be resistant to torsional bending to apply the necessary torque to rotate cartridge 106. Also because of the lack of axial movement, compartment 104 need not extend proximally beyond window 116 to accommodate the cartridge length. As seen in FIGS. 11 and 12, cartridge wall 108 is open along a portion of its circumference, to provide an arcuate cartridge opening 118 defined by end walls 110 and 112 and axial edges 120 and 121. Axial edge 120 provides the cutting edge, and supports a linear cutting element 124. Cutting element 124 is flat and thin (e.g. 0.015 inches thick), with a rectangular profile, to provide a lower profile cutting edge as compared to a wire.
  • [0062]
    FIGS. 13 and 14 illustrate the use of catheter 98 to remove a lesion 126 from an artery 128. The catheter is positioned to axially align window 116 with lesion 126, and further to angularly align the window and lesion. A control knob (not shown but similar to knob 58) is turned rather than pushed or pulled, to angularly align cartridge 106 such that opening 118 coincides with window 116 (FIG. 13). At this point, band 100 is flexed to urge the catheter upwardly against the arterial wall whereby a portion of lesion 126 enters compartment 104.
  • [0063]
    At this point, the knob is turned to rotate cartridge 106 clockwise as viewed in FIG. 13 while cutting element 124 is heated, thus to progressively cut the lesion. Cartridge rotation continues until cutting edge 120 is carried beyond the clockwise edge of window 116, which closes the window and captures acquired tissue. Then, catheter 98 is proximally withdrawn to remove captured tissue, or a plunger is used to remove tissue from the cartridge.
  • [0064]
    FIG. 15 illustrates an alternative embodiment cartridge 130 having an axial wall that is open at the distal end and along part of its circumference to define two cutting edges 132 and 134. A continuous wire 136 (0.030 inch diameter) is mounted to the cartridge and shaped to provide an arcuate segment 138 mounted to cutting edge 132, and a linear segment 140 along axial cutting edge 134. Accordingly, cartridge 130 can be used to effect axial cutting and arcuate cutting. Cartridge wall 142 is continuous over at least sixty percent of its circumference to enable axial and angular positioning that closes the associated catheter window, to insure capture of severed tissue. Drive member 144 can be a tube, rod or coil and has sufficient axial and torsional rigidity to impart axial and rotational movement to the cartridge.
  • [0065]
    FIG. 16 illustrates an alternative circuit for heating an arcuate cutting element 146. A conductor 148 connects the cutting element with an RF power supply 150. A second conductor 152 couples the power supply and an indifferent electrode 154. The indifferent electrode preferably is an electrode plate, typically applied to the back of the patient. The power supply provides an RF signal to the cutting element via conductor 148. The signal returns to the power supply via conductor 152. Between cutting element 146 and indifferent electrode 154, current flows through body tissue. Consequently, ohmic heating of tissue is the primary factor in raising the temperature of tissue adjacent the cutting element to the predetermined or desired level. Cutting element 146 preferably is platinum, for high biocompatibility and electrical conductivity. Accordingly cutting element heating from the current, while present to a degree, is slight compared to the ohmic heating effect. A controller 156 governs power supply 150 to provide the appropriate current in cutting element 146. While not shown in FIG. 16, a thermocouple or other sensing element can be mounted at the cutting element, to sense the temperature of the cutting element and adjacent tissue, and provide feedback to controller 156. As noted above, this approach (highly conductive cutting element and indifferent electrode) is presently the most preferred.
  • [0066]
    While the disclosure has focused on the treatment of coronary arteries, it is to be appreciated that devices in accordance with the present invention can be used to treat peripheral arteries and other vessels. These principles further can be applied in constructing and utilizing devices in neurology for removal of lesions in the carotid arteries, in gynecology for recanalization of Fallopian tubes, and in urology for removal of benign prostrate hyperplasia. The heating of the cutting element and adjacent tissue provides a fine, accurate cut to sever tissue at minimal risk of forming fragments, and provides a sealing action believed to reduce the incidence of restenosis. The cartridge can be either rotated or moved axially of the catheter, for greater versatility in severing unwanted tissue. After the cut, the cartridge completely closes the tissue-admitting window of the catheter, to insure complete capture of severed tissue.

Claims (1)

  1. 1. A device for heating tissue comprising: an elongate catheter having a proximal end and a distal end, a catheter wall defining a compartment within the catheter, a window through the catheter wall open to the compartment, and at least one lumen passing between a first opening in the proximal end and a second opening in the compartment, the first opening being connected to a vacuum source; a cartridge at least partially disposed within the compartment, the cartridge having a surface with a heating element disposed along the cartridge, and an energy source operatively coupled to the heating element, the cartridge being operable to urge tissue into the compartment when the first opening is connected to the vacuum source; and a controller coupled to the cartridge and operable to selectively position and move the cartridge relative to the catheter and thereby provide a controlled movement of the heating surface along the window.
US12768587 1995-01-23 2010-04-27 Tissue heating device and rf heating method with tissue attachment feature Abandoned US20100211057A1 (en)

Priority Applications (8)

Application Number Priority Date Filing Date Title
US08376226 US5665062A (en) 1995-01-23 1995-01-23 Atherectomy catheter and RF cutting method
US08899490 US5876369A (en) 1995-01-23 1997-07-19 Tissue removing catheter and RF cutting method
US09256020 US6214024B1 (en) 1995-01-23 1999-02-23 Tissue cutting catheter and RF cutting method
US09804009 US6540761B2 (en) 1995-01-23 2001-03-12 Tissue cutting/tissue removing device with vacuum feature
US10404720 US6872204B2 (en) 1995-01-23 2003-04-01 Tissue cutting catheter and RF cutting method
US10906164 US7172590B1 (en) 1995-01-23 2005-02-04 Tissue heating device and RF heating method with tissue attachment feature
US11671723 US20070129725A1 (en) 1995-01-23 2007-02-06 Tissue heating device and rf heating method with tissue attachment feature
US12768587 US20100211057A1 (en) 1995-01-23 2010-04-27 Tissue heating device and rf heating method with tissue attachment feature

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US12768587 US20100211057A1 (en) 1995-01-23 2010-04-27 Tissue heating device and rf heating method with tissue attachment feature

Publications (1)

Publication Number Publication Date
US20100211057A1 true true US20100211057A1 (en) 2010-08-19

Family

ID=23484166

Family Applications (8)

Application Number Title Priority Date Filing Date
US08376226 Expired - Lifetime US5665062A (en) 1995-01-23 1995-01-23 Atherectomy catheter and RF cutting method
US08899490 Expired - Fee Related US5876369A (en) 1995-01-23 1997-07-19 Tissue removing catheter and RF cutting method
US09256020 Expired - Lifetime US6214024B1 (en) 1995-01-23 1999-02-23 Tissue cutting catheter and RF cutting method
US09804009 Expired - Lifetime US6540761B2 (en) 1995-01-23 2001-03-12 Tissue cutting/tissue removing device with vacuum feature
US10404720 Expired - Fee Related US6872204B2 (en) 1995-01-23 2003-04-01 Tissue cutting catheter and RF cutting method
US10906164 Expired - Lifetime US7172590B1 (en) 1995-01-23 2005-02-04 Tissue heating device and RF heating method with tissue attachment feature
US11671723 Abandoned US20070129725A1 (en) 1995-01-23 2007-02-06 Tissue heating device and rf heating method with tissue attachment feature
US12768587 Abandoned US20100211057A1 (en) 1995-01-23 2010-04-27 Tissue heating device and rf heating method with tissue attachment feature

Family Applications Before (7)

Application Number Title Priority Date Filing Date
US08376226 Expired - Lifetime US5665062A (en) 1995-01-23 1995-01-23 Atherectomy catheter and RF cutting method
US08899490 Expired - Fee Related US5876369A (en) 1995-01-23 1997-07-19 Tissue removing catheter and RF cutting method
US09256020 Expired - Lifetime US6214024B1 (en) 1995-01-23 1999-02-23 Tissue cutting catheter and RF cutting method
US09804009 Expired - Lifetime US6540761B2 (en) 1995-01-23 2001-03-12 Tissue cutting/tissue removing device with vacuum feature
US10404720 Expired - Fee Related US6872204B2 (en) 1995-01-23 2003-04-01 Tissue cutting catheter and RF cutting method
US10906164 Expired - Lifetime US7172590B1 (en) 1995-01-23 2005-02-04 Tissue heating device and RF heating method with tissue attachment feature
US11671723 Abandoned US20070129725A1 (en) 1995-01-23 2007-02-06 Tissue heating device and rf heating method with tissue attachment feature

Country Status (2)

Country Link
US (8) US5665062A (en)
WO (1) WO1996022737A1 (en)

Families Citing this family (194)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5665062A (en) * 1995-01-23 1997-09-09 Houser; Russell A. Atherectomy catheter and RF cutting method
US6692445B2 (en) 1999-07-27 2004-02-17 Scimed Life Systems, Inc. Biopsy sampler
US6302875B1 (en) * 1996-10-11 2001-10-16 Transvascular, Inc. Catheters and related devices for forming passageways between blood vessels or other anatomical structures
DE69633411D1 (en) 1995-10-13 2004-10-21 Transvascular Inc A device for avoidance of arterial constrictions and / or to perform other interventions transvaskularer
US6375615B1 (en) * 1995-10-13 2002-04-23 Transvascular, Inc. Tissue penetrating catheters having integral imaging transducers and their methods of use
JPH11513577A (en) * 1995-10-13 1999-11-24 トランスバスキュラー インコーポレイテッド Apparatus for tissue between transluminal intervention, the system and method
US6241703B1 (en) * 1996-08-19 2001-06-05 Angiosonics Inc. Ultrasound transmission apparatus having a tip
US6120520A (en) 1997-05-27 2000-09-19 Angiotrax, Inc. Apparatus and methods for stimulating revascularization and/or tissue growth
US6102926A (en) 1996-12-02 2000-08-15 Angiotrax, Inc. Apparatus for percutaneously performing myocardial revascularization having means for sensing tissue parameters and methods of use
US6051008A (en) * 1996-12-02 2000-04-18 Angiotrax, Inc. Apparatus having stabilization members for percutaneously performing surgery and methods of use
US6019733A (en) 1997-09-19 2000-02-01 United States Surgical Corporation Biopsy apparatus and method
US6214001B1 (en) * 1997-09-19 2001-04-10 Oratec Interventions, Inc. Electrocauterizing tool for orthopedic shave devices
US6440138B1 (en) * 1998-04-06 2002-08-27 Kyphon Inc. Structures and methods for creating cavities in interior body regions
US6561998B1 (en) 1998-04-07 2003-05-13 Transvascular, Inc. Transluminal devices, systems and methods for enlarging interstitial penetration tracts
US6203505B1 (en) * 1998-06-05 2001-03-20 Advanced Cardiovascular Systems, Inc. Guidewires having a vapor deposited primer coat
US6113615A (en) * 1999-02-03 2000-09-05 Scimed Life Systems, Inc. Atherectomy burr including a bias wire
US6375676B1 (en) * 1999-05-17 2002-04-23 Advanced Cardiovascular Systems, Inc. Self-expanding stent with enhanced delivery precision and stent delivery system
WO2001074260A1 (en) * 2000-03-24 2001-10-11 Johns Hopkins University Peritoneal cavity device and method
US6666751B1 (en) * 2000-07-17 2003-12-23 Micron Technology, Inc. Deformable pad for chemical mechanical polishing
DE10049813C1 (en) * 2000-10-09 2002-04-18 Universitaetsklinikum Freiburg Instrument for the local removal of built-up matter at an aortic valve, in a human or animal heart, is a hollow catheter with a cutting unit at the far end within a closure cap for minimum invasion
US6589240B2 (en) 2001-08-28 2003-07-08 Rex Medical, L.P. Tissue biopsy apparatus with collapsible cutter
US6623437B2 (en) 2001-08-28 2003-09-23 Rex Medical, L.P. Tissue biopsy apparatus
US7338441B2 (en) * 2001-09-06 2008-03-04 Houser Russell A Superelastic/shape memory tissue stabilizers and surgical instruments
CA2479339C (en) 2002-03-19 2013-03-12 Bard Dublin Itc Limited Vacuum biopsy device
EP1524940B1 (en) 2002-03-19 2011-08-24 Bard Dublin ITC Limited Biopsy device and biopsy needle module that can be inserted into the biopsy device
US7756583B2 (en) 2002-04-08 2010-07-13 Ardian, Inc. Methods and apparatus for intravascularly-induced neuromodulation
US8347891B2 (en) 2002-04-08 2013-01-08 Medtronic Ardian Luxembourg S.A.R.L. Methods and apparatus for performing a non-continuous circumferential treatment of a body lumen
US7153315B2 (en) * 2002-06-11 2006-12-26 Boston Scientific Scimed, Inc. Catheter balloon with ultrasonic microscalpel blades
US7715896B2 (en) 2003-03-21 2010-05-11 Boston Scientific Scimed, Inc. Systems and methods for internal tissue penetration
DE10314240A1 (en) 2003-03-29 2004-10-07 Bard Dublin Itc Ltd., Crawley Pressure generating unit
DE20305093U1 (en) * 2003-03-29 2003-09-11 Heske Norbert F Coaxial cannula with sealing element
US7238182B2 (en) * 2003-04-25 2007-07-03 Medtronic, Inc. Device and method for transurethral prostate treatment
US20080114355A1 (en) * 2006-11-09 2008-05-15 Ncontact Surgical, Inc. Vacuum coagulation probes
US20040220514A1 (en) * 2003-05-01 2004-11-04 Medtronic Ave. Method and system for treating vulnerable plaque
US20040255957A1 (en) * 2003-05-01 2004-12-23 Robert Cafferata Method and system for treating vulnerable plaque
EP1641512A1 (en) * 2003-06-20 2006-04-05 Coloplast A/S A medical device comprising a braided portion
US7569052B2 (en) * 2003-09-12 2009-08-04 Boston Scientific Scimed, Inc. Ablation catheter with tissue protecting assembly
US9713730B2 (en) 2004-09-10 2017-07-25 Boston Scientific Scimed, Inc. Apparatus and method for treatment of in-stent restenosis
DE202004021944U1 (en) 2003-09-12 2013-07-16 Vessix Vascular, Inc. Selectable eccentric remodeling and / or ablation of atherosclerotic material
US6994705B2 (en) * 2003-09-29 2006-02-07 Ethicon-Endo Surgery, Inc. Endoscopic mucosal resection device with conductive tissue stop
US7186252B2 (en) * 2003-09-29 2007-03-06 Ethicon Endo-Surgery, Inc. Endoscopic mucosal resection device and method of use
US7169115B2 (en) 2003-09-29 2007-01-30 Ethicon Endo-Surgery, Inc. Endoscopic mucosal resection device with overtube and method of use
US8100822B2 (en) * 2004-03-16 2012-01-24 Macroplata Systems, Llc Anoscope for treating hemorrhoids without the trauma of cutting or the use of an endoscope
US20050251116A1 (en) * 2004-05-05 2005-11-10 Minnow Medical, Llc Imaging and eccentric atherosclerotic material laser remodeling and/or ablation catheter
EP1768571B1 (en) 2004-07-09 2012-03-21 Bard Peripheral Vascular, Inc. Firing system for biopsy device
CN101023006B (en) * 2004-08-26 2010-09-01 吉第联合股份公司 Rigid hinged-lid package for tobacco articles
US8257356B2 (en) 2004-10-15 2012-09-04 Baxano, Inc. Guidewire exchange systems to treat spinal stenosis
US20110004207A1 (en) 2004-10-15 2011-01-06 Baxano, Inc. Flexible Neural Localization Devices and Methods
CA2583906C (en) 2004-10-15 2011-12-06 Baxano, Inc. Devices and methods for tissue removal
US20100331883A1 (en) 2004-10-15 2010-12-30 Schmitz Gregory P Access and tissue modification systems and methods
US8221397B2 (en) 2004-10-15 2012-07-17 Baxano, Inc. Devices and methods for tissue modification
US8430881B2 (en) * 2004-10-15 2013-04-30 Baxano, Inc. Mechanical tissue modification devices and methods
US8092456B2 (en) 2005-10-15 2012-01-10 Baxano, Inc. Multiple pathways for spinal nerve root decompression from a single access point
US9101386B2 (en) 2004-10-15 2015-08-11 Amendia, Inc. Devices and methods for treating tissue
US8048080B2 (en) 2004-10-15 2011-11-01 Baxano, Inc. Flexible tissue rasp
US7887538B2 (en) * 2005-10-15 2011-02-15 Baxano, Inc. Methods and apparatus for tissue modification
US9247952B2 (en) 2004-10-15 2016-02-02 Amendia, Inc. Devices and methods for tissue access
US8617163B2 (en) 2004-10-15 2013-12-31 Baxano Surgical, Inc. Methods, systems and devices for carpal tunnel release
US7738968B2 (en) 2004-10-15 2010-06-15 Baxano, Inc. Devices and methods for selective surgical removal of tissue
US7738969B2 (en) 2004-10-15 2010-06-15 Baxano, Inc. Devices and methods for selective surgical removal of tissue
US8366712B2 (en) 2005-10-15 2013-02-05 Baxano, Inc. Multiple pathways for spinal nerve root decompression from a single access point
US8062300B2 (en) 2006-05-04 2011-11-22 Baxano, Inc. Tissue removal with at least partially flexible devices
US20110190772A1 (en) 2004-10-15 2011-08-04 Vahid Saadat Powered tissue modification devices and methods
US20060122458A1 (en) * 2004-10-15 2006-06-08 Baxano, Inc. Devices and methods for tissue access
US7578819B2 (en) * 2005-05-16 2009-08-25 Baxano, Inc. Spinal access and neural localization
US8062298B2 (en) 2005-10-15 2011-11-22 Baxano, Inc. Flexible tissue removal devices and methods
US7938830B2 (en) 2004-10-15 2011-05-10 Baxano, Inc. Powered tissue modification devices and methods
US7517321B2 (en) * 2005-01-31 2009-04-14 C. R. Bard, Inc. Quick cycle biopsy system
US9510732B2 (en) 2005-10-25 2016-12-06 Intuitive Surgical Operations, Inc. Methods and apparatus for efficient purging
US8078266B2 (en) * 2005-10-25 2011-12-13 Voyage Medical, Inc. Flow reduction hood systems
ES2565342T3 (en) 2005-03-28 2016-04-04 Vessix Vascular, Inc. electrical characterization and tissue intraluminal RF energy for controlled selective treatment of atheroma, and other target tissues
US8097012B2 (en) * 2005-07-27 2012-01-17 The Spectranetics Corporation Endocardial lead removing apparatus
US7993359B1 (en) * 2005-07-27 2011-08-09 The Spectrametics Corporation Endocardial lead removing apparatus
EP1921998A4 (en) 2005-08-10 2017-07-19 Bard Inc C R Single-insertion, multiple sampling biopsy device with linear drive
EP2196154B1 (en) 2005-08-10 2012-01-18 C.R.Bard, Inc. Transport system for single-insertion, multiple sample biopsy devices
CA2616714C (en) 2005-08-10 2017-01-24 Jon Taylor Single-insertion, multiple sample biopsy device with integrated markers
US20070213734A1 (en) * 2006-03-13 2007-09-13 Bleich Jeffery L Tissue modification barrier devices and methods
US20070119461A1 (en) * 2005-11-18 2007-05-31 Brian Biancucci Article isolation device and methods
US8019435B2 (en) 2006-05-02 2011-09-13 Boston Scientific Scimed, Inc. Control of arterial smooth muscle tone
US9314263B2 (en) 2006-06-30 2016-04-19 Atheromed, Inc. Atherectomy devices, systems, and methods
US9492192B2 (en) 2006-06-30 2016-11-15 Atheromed, Inc. Atherectomy devices, systems, and methods
US20080045986A1 (en) 2006-06-30 2008-02-21 Atheromed, Inc. Atherectomy devices and methods
US8628549B2 (en) 2006-06-30 2014-01-14 Atheromed, Inc. Atherectomy devices, systems, and methods
US20090018566A1 (en) 2006-06-30 2009-01-15 Artheromed, Inc. Atherectomy devices, systems, and methods
US8361094B2 (en) 2006-06-30 2013-01-29 Atheromed, Inc. Atherectomy devices and methods
US8007506B2 (en) 2006-06-30 2011-08-30 Atheromed, Inc. Atherectomy devices and methods
US7981128B2 (en) 2006-06-30 2011-07-19 Atheromed, Inc. Atherectomy devices and methods
US7559137B2 (en) * 2006-07-17 2009-07-14 Potomac Photonics, Inc. Method for providing electrically conductive paths in polymer tubing
US20080033465A1 (en) * 2006-08-01 2008-02-07 Baxano, Inc. Multi-Wire Tissue Cutter
US20080051812A1 (en) * 2006-08-01 2008-02-28 Baxano, Inc. Multi-Wire Tissue Cutter
WO2008024684A3 (en) 2006-08-21 2008-07-03 Bard Inc C R Self-contained handheld biopsy needle
US7857813B2 (en) 2006-08-29 2010-12-28 Baxano, Inc. Tissue access guidewire system and method
ES2663296T3 (en) 2006-10-06 2018-04-11 Bard Peripheral Vascular, Inc. Tissue handling system with reduced operator exposure
EP2076198A4 (en) 2006-10-18 2009-12-09 Minnow Medical Inc Inducing desirable temperature effects on body tissue
WO2008049084A3 (en) 2006-10-18 2008-08-07 Minnow Medical Inc Tuned rf energy and electrical tissue characterization for selective treatment of target tissues
JP5559539B2 (en) 2006-10-18 2014-07-23 べシックス・バスキュラー・インコーポレイテッド System to induce the temperature desired effect on the body tissue
EP2644105A3 (en) 2006-10-24 2017-06-14 C.R. Bard, Inc. Large sample low aspect ratio biopsy needle
US20080103412A1 (en) 2006-11-01 2008-05-01 Yem Chin Removing Tissue
US8192436B2 (en) 2007-12-07 2012-06-05 Baxano, Inc. Tissue modification devices
US8496653B2 (en) 2007-04-23 2013-07-30 Boston Scientific Scimed, Inc. Thrombus removal
WO2008150796A1 (en) * 2007-05-29 2008-12-11 Kassab Ghassan S Devices, systems, and methods for valve removal
US7959577B2 (en) 2007-09-06 2011-06-14 Baxano, Inc. Method, system, and apparatus for neural localization
US8070762B2 (en) 2007-10-22 2011-12-06 Atheromed Inc. Atherectomy devices and methods
US8236016B2 (en) 2007-10-22 2012-08-07 Atheromed, Inc. Atherectomy devices and methods
US8241225B2 (en) 2007-12-20 2012-08-14 C. R. Bard, Inc. Biopsy device
US7854706B2 (en) 2007-12-27 2010-12-21 Devicor Medical Products, Inc. Clutch and valving system for tetherless biopsy device
US8437938B2 (en) * 2008-01-15 2013-05-07 GM Global Technology Operations LLC Axle torque based cruise control
US9314253B2 (en) 2008-07-01 2016-04-19 Amendia, Inc. Tissue modification devices and methods
US8398641B2 (en) 2008-07-01 2013-03-19 Baxano, Inc. Tissue modification devices and methods
US8409206B2 (en) 2008-07-01 2013-04-02 Baxano, Inc. Tissue modification devices and methods
EP2328489A4 (en) 2008-07-14 2013-05-15 Baxano Inc Tissue modification devices
JP5622729B2 (en) * 2008-09-22 2014-11-12 べシックス・バスキュラー・インコーポレイテッド System to induce the temperature effects on body tissue
US8396548B2 (en) 2008-11-14 2013-03-12 Vessix Vascular, Inc. Selective drug delivery in a lumen
EP2355737A4 (en) 2008-11-17 2013-01-16 Vessix Vascular Inc Selective accumulation of energy with or without knowledge of tissue topography
EP2408378A4 (en) 2009-03-16 2013-10-09 Bard Inc C R Biopsy device having rotational cutting
WO2010120294A1 (en) 2009-04-15 2010-10-21 C.R. Bard, Inc. Biopsy apparatus having integrated fluid management
US8906052B1 (en) 2009-05-08 2014-12-09 University Of South Florida Method and device for the treatment of hypertrophic cardiomyopathy
US8551096B2 (en) 2009-05-13 2013-10-08 Boston Scientific Scimed, Inc. Directional delivery of energy and bioactives
US8206316B2 (en) 2009-06-12 2012-06-26 Devicor Medical Products, Inc. Tetherless biopsy device with reusable portion
US8394102B2 (en) 2009-06-25 2013-03-12 Baxano, Inc. Surgical tools for treatment of spinal stenosis
US9173641B2 (en) 2009-08-12 2015-11-03 C. R. Bard, Inc. Biopsy apparatus having integrated thumbwheel mechanism for manual rotation of biopsy cannula
US8485989B2 (en) 2009-09-01 2013-07-16 Bard Peripheral Vascular, Inc. Biopsy apparatus having a tissue sample retrieval mechanism
USD640977S1 (en) 2009-09-25 2011-07-05 C. R. Bard, Inc. Charging station for a battery operated biopsy device
US8597206B2 (en) 2009-10-12 2013-12-03 Bard Peripheral Vascular, Inc. Biopsy probe assembly having a mechanism to prevent misalignment of components prior to installation
US8430824B2 (en) 2009-10-29 2013-04-30 Bard Peripheral Vascular, Inc. Biopsy driver assembly having a control circuit for conserving battery power
US8506479B2 (en) 2009-12-16 2013-08-13 Macroplata, Inc. Substantially rigid and stable endoluminal surgical suite for treating a gastrointestinal lesion
US9565998B2 (en) 2009-12-16 2017-02-14 Boston Scientific Scimed, Inc. Multi-lumen-catheter retractor system for a minimally-invasive, operative gastrointestinal treatment
US9186131B2 (en) 2009-12-16 2015-11-17 Macroplata, Inc. Multi-lumen-catheter retractor system for a minimally-invasive, operative gastrointestinal treatment
US20110172688A1 (en) * 2010-01-11 2011-07-14 Tyco Healthcare Group Lp Conduit Harvesting Instrument and Method
KR20130108067A (en) 2010-04-09 2013-10-02 베식스 바스큘라 인코포레이티드 Power generating and control apparatus for the treatment of tissue
US9192790B2 (en) 2010-04-14 2015-11-24 Boston Scientific Scimed, Inc. Focused ultrasonic renal denervation
US9504486B2 (en) * 2010-04-19 2016-11-29 Cvdevices, Llc Devices, systems, and methods for valve removal
JP5796065B2 (en) 2010-04-26 2015-10-21 コヴィディエン エル ピー Treatment apparatus and method of the anatomical structure
EP2382923B1 (en) * 2010-04-28 2016-12-14 Sanovas, Inc. Pressure/vaccum actuated biopsy device
US8473067B2 (en) 2010-06-11 2013-06-25 Boston Scientific Scimed, Inc. Renal denervation and stimulation employing wireless vascular energy transfer arrangement
US9358365B2 (en) 2010-07-30 2016-06-07 Boston Scientific Scimed, Inc. Precision electrode movement control for renal nerve ablation
US9463062B2 (en) 2010-07-30 2016-10-11 Boston Scientific Scimed, Inc. Cooled conductive balloon RF catheter for renal nerve ablation
US9408661B2 (en) 2010-07-30 2016-08-09 Patrick A. Haverkost RF electrodes on multiple flexible wires for renal nerve ablation
US9155589B2 (en) 2010-07-30 2015-10-13 Boston Scientific Scimed, Inc. Sequential activation RF electrode set for renal nerve ablation
US9084609B2 (en) 2010-07-30 2015-07-21 Boston Scientific Scime, Inc. Spiral balloon catheter for renal nerve ablation
US9282991B2 (en) 2010-10-06 2016-03-15 Rex Medical, L.P. Cutting wire assembly with coating for use with a catheter
US8685050B2 (en) 2010-10-06 2014-04-01 Rex Medical L.P. Cutting wire assembly for use with a catheter
US8974451B2 (en) 2010-10-25 2015-03-10 Boston Scientific Scimed, Inc. Renal nerve ablation using conductive fluid jet and RF energy
US9220558B2 (en) 2010-10-27 2015-12-29 Boston Scientific Scimed, Inc. RF renal denervation catheter with multiple independent electrodes
US9028485B2 (en) 2010-11-15 2015-05-12 Boston Scientific Scimed, Inc. Self-expanding cooling electrode for renal nerve ablation
US9668811B2 (en) 2010-11-16 2017-06-06 Boston Scientific Scimed, Inc. Minimally invasive access for renal nerve ablation
US9089350B2 (en) 2010-11-16 2015-07-28 Boston Scientific Scimed, Inc. Renal denervation catheter with RF electrode and integral contrast dye injection arrangement
US9326751B2 (en) 2010-11-17 2016-05-03 Boston Scientific Scimed, Inc. Catheter guidance of external energy for renal denervation
US8685049B2 (en) 2010-11-18 2014-04-01 Rex Medical L.P. Cutting wire assembly for use with a catheter
US9060761B2 (en) 2010-11-18 2015-06-23 Boston Scientific Scime, Inc. Catheter-focused magnetic field induced renal nerve ablation
US9192435B2 (en) 2010-11-22 2015-11-24 Boston Scientific Scimed, Inc. Renal denervation catheter with cooled RF electrode
US8702736B2 (en) 2010-11-22 2014-04-22 Rex Medical L.P. Cutting wire assembly for use with a catheter
US9023034B2 (en) 2010-11-22 2015-05-05 Boston Scientific Scimed, Inc. Renal ablation electrode with force-activatable conduction apparatus
US20120157993A1 (en) 2010-12-15 2012-06-21 Jenson Mark L Bipolar Off-Wall Electrode Device for Renal Nerve Ablation
WO2012100095A1 (en) 2011-01-19 2012-07-26 Boston Scientific Scimed, Inc. Guide-compatible large-electrode catheter for renal nerve ablation with reduced arterial injury
US8784300B2 (en) * 2011-03-30 2014-07-22 Children's Hospital & Research Center Oakland Devices, systems, and methods for removing empyema from a pleural cavity
EP2694150A1 (en) 2011-04-08 2014-02-12 Covidien LP Iontophoresis drug delivery system and method for denervation of the renal sympathetic nerve and iontophoretic drug delivery
EP2734259B1 (en) 2011-07-20 2016-11-23 Boston Scientific Scimed, Inc. Percutaneous device to visualize, target and ablate nerves
US9186209B2 (en) 2011-07-22 2015-11-17 Boston Scientific Scimed, Inc. Nerve modulation system having helical guide
EP2765942B1 (en) 2011-10-10 2016-02-24 Boston Scientific Scimed, Inc. Medical devices including ablation electrodes
US9420955B2 (en) 2011-10-11 2016-08-23 Boston Scientific Scimed, Inc. Intravascular temperature monitoring system and method
US9364284B2 (en) 2011-10-12 2016-06-14 Boston Scientific Scimed, Inc. Method of making an off-wall spacer cage
CN103957825A (en) 2011-10-13 2014-07-30 阿瑟罗迈德公司 Atherectomy apparatus, systems and methods
WO2013059202A1 (en) 2011-10-18 2013-04-25 Boston Scientific Scimed, Inc. Integrated crossing balloon catheter
EP2768563B1 (en) 2011-10-18 2016-11-09 Boston Scientific Scimed, Inc. Deflectable medical devices
US8632458B2 (en) 2011-10-26 2014-01-21 Macroplata Inc. Gentle hemorrhoid treatment offering a substantially painless healing
WO2013070724A1 (en) 2011-11-08 2013-05-16 Boston Scientific Scimed, Inc. Ostial renal nerve ablation
US9119600B2 (en) 2011-11-15 2015-09-01 Boston Scientific Scimed, Inc. Device and methods for renal nerve modulation monitoring
US9119632B2 (en) 2011-11-21 2015-09-01 Boston Scientific Scimed, Inc. Deflectable renal nerve ablation catheter
US9265969B2 (en) 2011-12-21 2016-02-23 Cardiac Pacemakers, Inc. Methods for modulating cell function
US9037259B2 (en) 2011-12-23 2015-05-19 Vessix Vascular, Inc. Methods and apparatuses for remodeling tissue of or adjacent to a body passage
CN104135958B (en) 2011-12-28 2017-05-03 波士顿科学西美德公司 There are new methods and apparatus with an ablation catheter ablation element becomes transferred polymer nerve
US9050106B2 (en) 2011-12-29 2015-06-09 Boston Scientific Scimed, Inc. Off-wall electrode device and methods for nerve modulation
CN104379212B (en) 2012-04-22 2016-08-31 纽乌罗有限公司 Changes in bladder tissue for overactive bladder
US9883906B2 (en) 2012-04-22 2018-02-06 Newuro, B.V. Bladder tissue modification for overactive bladder disorders
US8932211B2 (en) 2012-06-22 2015-01-13 Macroplata, Inc. Floating, multi-lumen-catheter retractor system for a minimally-invasive, operative gastrointestinal treatment
US9173696B2 (en) 2012-09-17 2015-11-03 Boston Scientific Scimed, Inc. Self-positioning electrode system and method for renal nerve modulation
US9204921B2 (en) 2012-12-13 2015-12-08 Cook Medical Technologies Llc RF energy controller and method for electrosurgical medical devices
US9364277B2 (en) 2012-12-13 2016-06-14 Cook Medical Technologies Llc RF energy controller and method for electrosurgical medical devices
US9956033B2 (en) 2013-03-11 2018-05-01 Boston Scientific Scimed, Inc. Medical devices for modulating nerves
US9693821B2 (en) 2013-03-11 2017-07-04 Boston Scientific Scimed, Inc. Medical devices for modulating nerves
US9808311B2 (en) 2013-03-13 2017-11-07 Boston Scientific Scimed, Inc. Deflectable medical devices
US20140276074A1 (en) * 2013-03-13 2014-09-18 W.L. Gore & Associates, Inc. Flexible Driveshafts with Bi-Directionally Balanced Torsional Stiffness Properties
US9297845B2 (en) 2013-03-15 2016-03-29 Boston Scientific Scimed, Inc. Medical devices and methods for treatment of hypertension that utilize impedance compensation
EP2967734A1 (en) 2013-03-15 2016-01-20 Boston Scientific Scimed, Inc. Methods and apparatuses for remodeling tissue of or adjacent to a body passage
CN105473091A (en) 2013-06-21 2016-04-06 波士顿科学国际有限公司 Renal denervation balloon catheter with ride along electrode support
US9707036B2 (en) 2013-06-25 2017-07-18 Boston Scientific Scimed, Inc. Devices and methods for nerve modulation using localized indifferent electrodes
CN105358084A (en) 2013-07-01 2016-02-24 波士顿科学国际有限公司 Medical devices for renal nerve ablation
EP3049007A1 (en) 2013-07-19 2016-08-03 Boston Scientific Scimed, Inc. Spiral bipolar electrode renal denervation balloon
EP3041425A1 (en) 2013-09-04 2016-07-13 Boston Scientific Scimed, Inc. Radio frequency (rf) balloon catheter having flushing and cooling capability
CN105592778A (en) 2013-10-14 2016-05-18 波士顿科学医学有限公司 High resolution cardiac mapping electrode array catheter
US9770606B2 (en) 2013-10-15 2017-09-26 Boston Scientific Scimed, Inc. Ultrasound ablation catheter with cooling infusion and centering basket
CN105636537A (en) 2013-10-15 2016-06-01 波士顿科学国际有限公司 Medical device balloon
WO2015119890A1 (en) 2014-02-04 2015-08-13 Boston Scientific Scimed, Inc. Alternative placement of thermal sensors on bipolar electrode

Citations (70)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4254763A (en) * 1979-06-07 1981-03-10 Codman & Shurtleff, Inc. Surgical retractor assembly
US4638802A (en) * 1984-09-21 1987-01-27 Olympus Optical Co., Ltd. High frequency instrument for incision and excision
US4719914A (en) * 1986-12-24 1988-01-19 Johnson Gerald W Electrosurgical instrument
US4834729A (en) * 1986-12-30 1989-05-30 Dyonics, Inc. Arthroscopic surgical instrument
US4986807A (en) * 1989-01-23 1991-01-22 Interventional Technologies, Inc. Atherectomy cutter with radially projecting blade
US4994067A (en) * 1989-02-17 1991-02-19 American Biomed, Inc. Distal atherectomy catheter
US5007917A (en) * 1990-03-08 1991-04-16 Stryker Corporation Single blade cutter for arthroscopic surgery
US5009659A (en) * 1989-10-30 1991-04-23 Schneider (Usa) Inc. Fiber tip atherectomy catheter
US5078723A (en) * 1989-05-08 1992-01-07 Medtronic, Inc. Atherectomy device
US5078722A (en) * 1990-08-14 1992-01-07 Cordis Corporation Method and apparatus for removing deposits from a vessel
US5080660A (en) * 1990-05-11 1992-01-14 Applied Urology, Inc. Electrosurgical electrode
US5085662A (en) * 1989-11-13 1992-02-04 Scimed Life Systems, Inc. Atherectomy catheter and related components
US5087265A (en) * 1989-02-17 1992-02-11 American Biomed, Inc. Distal atherectomy catheter
US5087256A (en) * 1990-01-12 1992-02-11 Metcal Inc. Thermal atherectomy device
US5098431A (en) * 1989-04-13 1992-03-24 Everest Medical Corporation RF ablation catheter
US5100426A (en) * 1989-07-26 1992-03-31 Fts Engineering, Inc. Catheter for performing an atherectomy procedure
US5100424A (en) * 1990-05-21 1992-03-31 Cardiovascular Imaging Systems, Inc. Intravascular catheter having combined imaging abrasion head
US5106364A (en) * 1989-07-07 1992-04-21 Kabushiki Kaisha Topcon Surgical cutter
US5181920A (en) * 1990-06-08 1993-01-26 Devices For Vascular Intervention, Inc. Atherectomy device with angioplasty balloon and method
US5197964A (en) * 1991-11-12 1993-03-30 Everest Medical Corporation Bipolar instrument utilizing one stationary electrode and one movable electrode
US5284486A (en) * 1991-06-11 1994-02-08 Microvena Corporation Self-centering mechanical medical device
US5312425A (en) * 1989-09-12 1994-05-17 Devices For Vascular Intervention, Inc. Atherectomy device having helical blade and blade guide
US5395313A (en) * 1993-08-13 1995-03-07 Naves; Neil H. Reciprocating arthroscopic shaver
US5409454A (en) * 1991-02-19 1995-04-25 Arrow International Investment Corp. Apparatus for atherectomy
US5415656A (en) * 1993-09-28 1995-05-16 American Medical Systems, Inc. Electrosurgical apparatus
US5505210A (en) * 1989-11-06 1996-04-09 Mectra Labs, Inc. Lavage with tissue cutting cannula
US5507760A (en) * 1993-11-09 1996-04-16 Devices For Vascular Intervention, Inc. Cutter device
US5514115A (en) * 1993-07-07 1996-05-07 Device For Vascular Intervention, Inc. Flexible housing for intracorporeal use
US5597378A (en) * 1983-10-14 1997-01-28 Raychem Corporation Medical devices incorporating SIM alloy elements
US5628746A (en) * 1989-01-18 1997-05-13 Applied Medical Resources Corporation Dilatation catheter assembly with cutting element and method of using the same
US5727569A (en) * 1996-02-20 1998-03-17 Cardiothoracic Systems, Inc. Surgical devices for imposing a negative pressure to fix the position of cardiac tissue during surgery
US5749892A (en) * 1994-08-31 1998-05-12 Heartport, Inc. Device for isolating a surgical site
US5875782A (en) * 1996-11-14 1999-03-02 Cardiothoracic Systems, Inc. Methods and devices for minimally invasive coronary artery revascularization on a beating heart without cardiopulmonary bypass
US5876369A (en) * 1995-01-23 1999-03-02 Advanced Catheter Engineering Tissue removing catheter and RF cutting method
US5894843A (en) * 1996-02-20 1999-04-20 Cardiothoracic Systems, Inc. Surgical method for stabilizing the beating heart during coronary artery bypass graft surgery
US5899425A (en) * 1997-05-02 1999-05-04 Medtronic, Inc. Adjustable supporting bracket having plural ball and socket joints
US5904657A (en) * 1997-02-26 1999-05-18 Unsworth; John D. System for guiding devices in body lumens
US6015378A (en) * 1995-09-20 2000-01-18 Medtronic, Inc. Method and apparatus for temporarily immobilizing a local area tissue
US6019722A (en) * 1997-09-17 2000-02-01 Guidant Corporation Device to permit offpump beating heart coronary bypass surgery
US6036641A (en) * 1996-02-20 2000-03-14 Cardiothoracic System, Inc. Surgical instruments for stabilizing the beating heart during coronary artery bypass graft surgery
US6206827B1 (en) * 1996-12-18 2001-03-27 Guidant Corporation Apparatus and method for tissue and organ stabilization
US6210323B1 (en) * 1998-05-05 2001-04-03 The University Of British Columbia Surgical arm and tissue stabilizer
US6231506B1 (en) * 1999-05-04 2001-05-15 Cardiothoracic Systems, Inc. Method and apparatus for creating a working opening through an incision
US6231585B1 (en) * 1997-11-20 2001-05-15 Medivas, Llc Device for stabilizing a treatment site and method of use
US20020002372A1 (en) * 2000-04-27 2002-01-03 Medtronic, Inc. Suction stabilized epicardial ablation devices
US6338712B2 (en) * 1997-09-17 2002-01-15 Origin Medsystems, Inc. Device to permit offpump beating heart coronary bypass surgery
US6364876B1 (en) * 1998-10-23 2002-04-02 Afx, Inc. Vacuum-assisted securing apparatus for a microwave ablation instrument
US20020042595A1 (en) * 2000-10-11 2002-04-11 Medcanica, Inc. Method of performing port off-pump beating heart coronary artery bypass surgery
US20020042603A1 (en) * 2000-10-11 2002-04-11 Medcanica, Inc. System for performing port off-pump beating heart coronary artery bypass surgery
US20020045888A1 (en) * 1998-11-20 2002-04-18 Intuitive Surgical, Inc. Stabilizer for robotic beating-heart surgery
US6511416B1 (en) * 1999-08-03 2003-01-28 Cardiothoracic Systems, Inc. Tissue stabilizer and methods of use
US6514250B1 (en) * 2000-04-27 2003-02-04 Medtronic, Inc. Suction stabilized epicardial ablation devices
US20030036677A1 (en) * 1996-02-20 2003-02-20 Taylor Charles S. Surgical devices for imposing a negative pressure to stabilize the cardiac tissue during surgery
US20030060685A1 (en) * 2001-09-06 2003-03-27 Houser Russell A. Superelastic/shape memory tissue stabilizers and surgical instruments
US20030078470A1 (en) * 1995-09-20 2003-04-24 Cornelius Borst Method and apparatus for temporarily immobilizing a local area of tissue
US6849075B2 (en) * 2001-12-04 2005-02-01 Estech, Inc. Cardiac ablation devices and methods
US20050065506A1 (en) * 2003-09-12 2005-03-24 Scimed Life Systems, Inc. Vacuum-based catheter stabilizer
US20060009762A1 (en) * 2002-06-14 2006-01-12 Ablatrics, Inc. Vacuum coagulation probe for atrial fibrillation treatment
US20060015165A1 (en) * 2001-12-04 2006-01-19 Bertolero Arthur A Conduction block verification probe and method of use
US20060025762A1 (en) * 2004-05-14 2006-02-02 Mohan Ashik A Ablation probe with stabilizing member
US7018328B2 (en) * 2000-02-11 2006-03-28 Endoscopic Technologies, Inc. Tissue stabilizer
US20070043351A1 (en) * 2003-04-29 2007-02-22 Ncontact Surgical, Inc. Vacuum coagulation probes
US7207988B2 (en) * 1999-10-29 2007-04-24 Medtronic Inc. Method and apparatus for providing intra-pericardial access
US20080009747A1 (en) * 2005-02-02 2008-01-10 Voyage Medical, Inc. Transmural subsurface interrogation and ablation
US20080015569A1 (en) * 2005-02-02 2008-01-17 Voyage Medical, Inc. Methods and apparatus for treatment of atrial fibrillation
US20080015445A1 (en) * 2005-02-02 2008-01-17 Voyage Medical, Inc. Tissue visualization device and method variations
US20080033290A1 (en) * 2005-10-25 2008-02-07 Voyage Medical, Inc. Delivery of biological compounds to ischemic and/or infarcted tissue
US20080058650A1 (en) * 2006-09-01 2008-03-06 Voyage Medical, Inc. Coronary sinus cannulation
US20080058591A1 (en) * 2005-10-25 2008-03-06 Voyage Medical, Inc. Tissue visualization device and method variations
US20080097476A1 (en) * 2006-09-01 2008-04-24 Voyage Medical, Inc. Precision control systems for tissue visualization and manipulation assemblies

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4793359A (en) * 1987-04-24 1988-12-27 Gv Medical, Inc. Centering balloon structure for transluminal angioplasty catheter
US4966596A (en) * 1988-08-08 1990-10-30 The Beth Israel Hospital Association Laser atherectomy catheter
US5092873A (en) * 1990-02-28 1992-03-03 Devices For Vascular Intervention, Inc. Balloon configuration for atherectomy catheter
US5222966A (en) * 1990-02-28 1993-06-29 Devices For Vascular Intervention, Inc. Balloon connection and inflation lumen for atherectomy catheter
US5366463A (en) * 1990-05-02 1994-11-22 Ryan William J Atherectomy catheter for the removal of atherosclerosis from within blood vessels
US5368603A (en) * 1990-06-05 1994-11-29 Halliburton; Alexander G. Endarterectomy catheter, and method of use thereof
US5242460A (en) * 1990-10-25 1993-09-07 Devices For Vascular Intervention, Inc. Atherectomy catheter having axially-disposed cutting edge
US5171255A (en) * 1990-11-21 1992-12-15 Everest Medical Corporation Biopsy device
US5250059A (en) * 1992-01-22 1993-10-05 Devices For Vascular Intervention, Inc. Atherectomy catheter having flexible nose cone
US5217458A (en) 1992-04-09 1993-06-08 Everest Medical Corporation Bipolar biopsy device utilizing a rotatable, single-hinged moving element
US5342359A (en) 1993-02-05 1994-08-30 Everest Medical Corporation Bipolar coagulation device
CA2161688A1 (en) * 1993-05-07 1994-11-24 Sdgi Holdings, Inc. Surgical cutting instrument
US5364395A (en) * 1993-05-14 1994-11-15 West Jr Hugh S Arthroscopic surgical instrument with cauterizing capability
US5441510A (en) * 1993-09-01 1995-08-15 Technology Development Center Bi-axial cutter apparatus for catheter
US5569284A (en) * 1994-09-23 1996-10-29 United States Surgical Corporation Morcellator
US5571130A (en) * 1994-10-04 1996-11-05 Advanced Cardiovascular Systems, Inc. Atherectomy and prostectomy system
US5578030A (en) * 1994-11-04 1996-11-26 Levin; John M. Biopsy needle with cauterization feature
US5474532A (en) * 1994-11-22 1995-12-12 Alcon Laboratories, Inc. Cutting blade for a vitreous cutter
US5782795A (en) * 1995-06-30 1998-07-21 Xomed Surgical Products, Inc. Surgical suction cutting instrument with internal irrigation

Patent Citations (99)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4254763A (en) * 1979-06-07 1981-03-10 Codman & Shurtleff, Inc. Surgical retractor assembly
US5597378A (en) * 1983-10-14 1997-01-28 Raychem Corporation Medical devices incorporating SIM alloy elements
US4638802A (en) * 1984-09-21 1987-01-27 Olympus Optical Co., Ltd. High frequency instrument for incision and excision
US4719914A (en) * 1986-12-24 1988-01-19 Johnson Gerald W Electrosurgical instrument
US4834729A (en) * 1986-12-30 1989-05-30 Dyonics, Inc. Arthroscopic surgical instrument
US5628746A (en) * 1989-01-18 1997-05-13 Applied Medical Resources Corporation Dilatation catheter assembly with cutting element and method of using the same
US4986807A (en) * 1989-01-23 1991-01-22 Interventional Technologies, Inc. Atherectomy cutter with radially projecting blade
US4994067A (en) * 1989-02-17 1991-02-19 American Biomed, Inc. Distal atherectomy catheter
US5087265A (en) * 1989-02-17 1992-02-11 American Biomed, Inc. Distal atherectomy catheter
US5098431A (en) * 1989-04-13 1992-03-24 Everest Medical Corporation RF ablation catheter
US5078723A (en) * 1989-05-08 1992-01-07 Medtronic, Inc. Atherectomy device
US5106364A (en) * 1989-07-07 1992-04-21 Kabushiki Kaisha Topcon Surgical cutter
US5100426A (en) * 1989-07-26 1992-03-31 Fts Engineering, Inc. Catheter for performing an atherectomy procedure
US5312425A (en) * 1989-09-12 1994-05-17 Devices For Vascular Intervention, Inc. Atherectomy device having helical blade and blade guide
US5009659A (en) * 1989-10-30 1991-04-23 Schneider (Usa) Inc. Fiber tip atherectomy catheter
US5505210A (en) * 1989-11-06 1996-04-09 Mectra Labs, Inc. Lavage with tissue cutting cannula
US5085662A (en) * 1989-11-13 1992-02-04 Scimed Life Systems, Inc. Atherectomy catheter and related components
US5087256A (en) * 1990-01-12 1992-02-11 Metcal Inc. Thermal atherectomy device
US5007917A (en) * 1990-03-08 1991-04-16 Stryker Corporation Single blade cutter for arthroscopic surgery
US5080660A (en) * 1990-05-11 1992-01-14 Applied Urology, Inc. Electrosurgical electrode
US5100424A (en) * 1990-05-21 1992-03-31 Cardiovascular Imaging Systems, Inc. Intravascular catheter having combined imaging abrasion head
US5895397A (en) * 1990-05-21 1999-04-20 Cardiovascular Imaging Systems, Inc. Intravascular catheter having combined imaging abrasion head
US5181920A (en) * 1990-06-08 1993-01-26 Devices For Vascular Intervention, Inc. Atherectomy device with angioplasty balloon and method
US5078722A (en) * 1990-08-14 1992-01-07 Cordis Corporation Method and apparatus for removing deposits from a vessel
US5409454A (en) * 1991-02-19 1995-04-25 Arrow International Investment Corp. Apparatus for atherectomy
US5284486A (en) * 1991-06-11 1994-02-08 Microvena Corporation Self-centering mechanical medical device
US5197964A (en) * 1991-11-12 1993-03-30 Everest Medical Corporation Bipolar instrument utilizing one stationary electrode and one movable electrode
US5290286A (en) * 1991-11-12 1994-03-01 Everest Medical Corporation Bipolar instrument utilizing one stationary electrode and one movable electrode
US5514115A (en) * 1993-07-07 1996-05-07 Device For Vascular Intervention, Inc. Flexible housing for intracorporeal use
US5395313A (en) * 1993-08-13 1995-03-07 Naves; Neil H. Reciprocating arthroscopic shaver
US5415656A (en) * 1993-09-28 1995-05-16 American Medical Systems, Inc. Electrosurgical apparatus
US5507760A (en) * 1993-11-09 1996-04-16 Devices For Vascular Intervention, Inc. Cutter device
US20030055318A1 (en) * 1994-08-31 2003-03-20 Vierra Mark A. Device and method for isolating a surgical site
US5749892A (en) * 1994-08-31 1998-05-12 Heartport, Inc. Device for isolating a surgical site
US6017304A (en) * 1994-08-31 2000-01-25 Vierra; Mark A. Device and method for isolating a surgical site
US5876369A (en) * 1995-01-23 1999-03-02 Advanced Catheter Engineering Tissue removing catheter and RF cutting method
US6540761B2 (en) * 1995-01-23 2003-04-01 Russell A. Houser Tissue cutting/tissue removing device with vacuum feature
US20020013580A1 (en) * 1995-01-23 2002-01-31 Houser Russell A. Tissue cutting catheter with temperature control and RF cutting method
US20040002706A1 (en) * 1995-01-23 2004-01-01 Houser Russell A. Tissue cutting catheter and RF cutting method
US6214024B1 (en) * 1995-01-23 2001-04-10 Russell U. Houser Tissue cutting catheter and RF cutting method
US7172590B1 (en) * 1995-01-23 2007-02-06 Russell A. Houser Tissue heating device and RF heating method with tissue attachment feature
US6872204B2 (en) * 1995-01-23 2005-03-29 Russell A. Tissue cutting catheter and RF cutting method
US6015378A (en) * 1995-09-20 2000-01-18 Medtronic, Inc. Method and apparatus for temporarily immobilizing a local area tissue
US6371906B1 (en) * 1995-09-20 2002-04-16 Medtronic, Inc. Method and apparatus for temporarily immobilizing a local area of tissue
US6334843B1 (en) * 1995-09-20 2002-01-01 Medtronic, Inc. Method and apparatus for temporarily immobilizing a local area of tissue
US20030078470A1 (en) * 1995-09-20 2003-04-24 Cornelius Borst Method and apparatus for temporarily immobilizing a local area of tissue
US6364826B1 (en) * 1995-09-20 2002-04-02 Medtronic, Inc. Method and apparatus for temporarily immobilizing a local area of tissue
US6350229B1 (en) * 1995-09-20 2002-02-26 Medtronic, Inc. Method and apparatus for temporarily immobilizing a local area of tissue
US6336898B1 (en) * 1995-09-20 2002-01-08 Medtronic, Inc. Method and apparatus for temporarily immobilizing a local area of tissue
US5727569A (en) * 1996-02-20 1998-03-17 Cardiothoracic Systems, Inc. Surgical devices for imposing a negative pressure to fix the position of cardiac tissue during surgery
US20030036677A1 (en) * 1996-02-20 2003-02-20 Taylor Charles S. Surgical devices for imposing a negative pressure to stabilize the cardiac tissue during surgery
US5894843A (en) * 1996-02-20 1999-04-20 Cardiothoracic Systems, Inc. Surgical method for stabilizing the beating heart during coronary artery bypass graft surgery
US6050266A (en) * 1996-02-20 2000-04-18 Cardiothracic Systems, Inc. Procedures for stabilizing the beating heart during coronary artery bypass graft surgery
US6036641A (en) * 1996-02-20 2000-03-14 Cardiothoracic System, Inc. Surgical instruments for stabilizing the beating heart during coronary artery bypass graft surgery
US6032672A (en) * 1996-02-20 2000-03-07 Cardiothoracic Systems, Inc. Surgical devices for imposing a negative pressure to stabilize cardiac tissue during surgery
US5906607A (en) * 1996-02-20 1999-05-25 Cardiothoracic Systems, Inc. Surgical devices for imposing a negative pressure to stabilize cardiac tissue during surgery
US20020040182A1 (en) * 1996-02-20 2002-04-04 Benetti Federico J. Surgical instruments and procedures for stabilizing the beating heart during coronary artery bypass graft surgery
US20020010388A1 (en) * 1996-02-20 2002-01-24 Charles S. Taylor Surgical instrument for stabilizing the beating heart during coronary artery bypass graft surgery
US6213941B1 (en) * 1996-02-20 2001-04-10 Cardiothoracic Systems, Inc. Surgical instruments for stabilizing the beating heart during coronary bypass graft surgery
US6346077B1 (en) * 1996-02-20 2002-02-12 Cardiothoracic Systems, Inc. Surgical instrument for stabilizing the beating heart during coronary artery bypass graft surgery
US5875782A (en) * 1996-11-14 1999-03-02 Cardiothoracic Systems, Inc. Methods and devices for minimally invasive coronary artery revascularization on a beating heart without cardiopulmonary bypass
US6206827B1 (en) * 1996-12-18 2001-03-27 Guidant Corporation Apparatus and method for tissue and organ stabilization
US5904657A (en) * 1997-02-26 1999-05-18 Unsworth; John D. System for guiding devices in body lumens
US5899425A (en) * 1997-05-02 1999-05-04 Medtronic, Inc. Adjustable supporting bracket having plural ball and socket joints
US6019722A (en) * 1997-09-17 2000-02-01 Guidant Corporation Device to permit offpump beating heart coronary bypass surgery
US6338712B2 (en) * 1997-09-17 2002-01-15 Origin Medsystems, Inc. Device to permit offpump beating heart coronary bypass surgery
US6361493B1 (en) * 1997-09-17 2002-03-26 Origin Medsystems, Inc. Device to permit offpump beating heart coronary bypass surgery
US20020049369A1 (en) * 1997-09-17 2002-04-25 Spence Paul A. Device to permit offpump beating heart coronary bypass surgery
US6231585B1 (en) * 1997-11-20 2001-05-15 Medivas, Llc Device for stabilizing a treatment site and method of use
US6210323B1 (en) * 1998-05-05 2001-04-03 The University Of British Columbia Surgical arm and tissue stabilizer
US20060015094A1 (en) * 1998-10-23 2006-01-19 Lyndall Erb Vacuum-assisted securing apparatus for a microwave ablation instrument
US20030036754A1 (en) * 1998-10-23 2003-02-20 Lyndall Erb Vacuum-assisted securing apparatus for a microwave ablation instrument
US6364876B1 (en) * 1998-10-23 2002-04-02 Afx, Inc. Vacuum-assisted securing apparatus for a microwave ablation instrument
US20020045888A1 (en) * 1998-11-20 2002-04-18 Intuitive Surgical, Inc. Stabilizer for robotic beating-heart surgery
US6231506B1 (en) * 1999-05-04 2001-05-15 Cardiothoracic Systems, Inc. Method and apparatus for creating a working opening through an incision
US20010002429A1 (en) * 1999-05-04 2001-05-31 Hu Lawrence W. Method and apparatus for creating a working opening through an incision
US6511416B1 (en) * 1999-08-03 2003-01-28 Cardiothoracic Systems, Inc. Tissue stabilizer and methods of use
US7207988B2 (en) * 1999-10-29 2007-04-24 Medtronic Inc. Method and apparatus for providing intra-pericardial access
US7018328B2 (en) * 2000-02-11 2006-03-28 Endoscopic Technologies, Inc. Tissue stabilizer
US6514250B1 (en) * 2000-04-27 2003-02-04 Medtronic, Inc. Suction stabilized epicardial ablation devices
US20020002372A1 (en) * 2000-04-27 2002-01-03 Medtronic, Inc. Suction stabilized epicardial ablation devices
US20020042603A1 (en) * 2000-10-11 2002-04-11 Medcanica, Inc. System for performing port off-pump beating heart coronary artery bypass surgery
US20020042595A1 (en) * 2000-10-11 2002-04-11 Medcanica, Inc. Method of performing port off-pump beating heart coronary artery bypass surgery
US6503245B2 (en) * 2000-10-11 2003-01-07 Medcanica, Inc. Method of performing port off-pump beating heart coronary artery bypass surgery
US7338441B2 (en) * 2001-09-06 2008-03-04 Houser Russell A Superelastic/shape memory tissue stabilizers and surgical instruments
US20030060685A1 (en) * 2001-09-06 2003-03-27 Houser Russell A. Superelastic/shape memory tissue stabilizers and surgical instruments
US20060015165A1 (en) * 2001-12-04 2006-01-19 Bertolero Arthur A Conduction block verification probe and method of use
US6849075B2 (en) * 2001-12-04 2005-02-01 Estech, Inc. Cardiac ablation devices and methods
US20060009762A1 (en) * 2002-06-14 2006-01-12 Ablatrics, Inc. Vacuum coagulation probe for atrial fibrillation treatment
US20070043351A1 (en) * 2003-04-29 2007-02-22 Ncontact Surgical, Inc. Vacuum coagulation probes
US20050065506A1 (en) * 2003-09-12 2005-03-24 Scimed Life Systems, Inc. Vacuum-based catheter stabilizer
US20060025762A1 (en) * 2004-05-14 2006-02-02 Mohan Ashik A Ablation probe with stabilizing member
US20080009747A1 (en) * 2005-02-02 2008-01-10 Voyage Medical, Inc. Transmural subsurface interrogation and ablation
US20080015445A1 (en) * 2005-02-02 2008-01-17 Voyage Medical, Inc. Tissue visualization device and method variations
US20080015569A1 (en) * 2005-02-02 2008-01-17 Voyage Medical, Inc. Methods and apparatus for treatment of atrial fibrillation
US20080033290A1 (en) * 2005-10-25 2008-02-07 Voyage Medical, Inc. Delivery of biological compounds to ischemic and/or infarcted tissue
US20080058591A1 (en) * 2005-10-25 2008-03-06 Voyage Medical, Inc. Tissue visualization device and method variations
US20080097476A1 (en) * 2006-09-01 2008-04-24 Voyage Medical, Inc. Precision control systems for tissue visualization and manipulation assemblies
US20080058650A1 (en) * 2006-09-01 2008-03-06 Voyage Medical, Inc. Coronary sinus cannulation

Also Published As

Publication number Publication date Type
US6214024B1 (en) 2001-04-10 grant
US5876369A (en) 1999-03-02 grant
US7172590B1 (en) 2007-02-06 grant
US20040002706A1 (en) 2004-01-01 application
US20020013580A1 (en) 2002-01-31 application
WO1996022737A1 (en) 1996-08-01 application
US20070129725A1 (en) 2007-06-07 application
US6872204B2 (en) 2005-03-29 grant
US5665062A (en) 1997-09-09 grant
US6540761B2 (en) 2003-04-01 grant

Similar Documents

Publication Publication Date Title
US6053913A (en) Rapid exchange stented balloon catheter having ablation capabilities
US6517534B1 (en) Peri-urethral ablation
US5250060A (en) Angioplasty apparatus
US4998933A (en) Thermal angioplasty catheter and method
US6015405A (en) Device for forming holes in tissue
US6074389A (en) Electrosurgery with cooled electrodes
US7166105B2 (en) Pen-type electrosurgical instrument
US5980516A (en) Method and apparatus for R-F ablation
US5876398A (en) Method and apparatus for R-F ablation
US6749608B2 (en) Adenoid curette electrosurgical probe
US6016809A (en) Method and apparatus for R-F ablation
US6280441B1 (en) Apparatus and method for RF lesioning
US6752806B2 (en) Unrollable tip for a catheter
US6045532A (en) Systems and methods for electrosurgical treatment of tissue in the brain and spinal cord
US5904698A (en) Surgical shaving device for use within body conduits
US6245067B1 (en) Ablation device and methods having perpendicular electrodes
US6692445B2 (en) Biopsy sampler
US6123703A (en) Ablation catheter and methods for treating tissues
US5290282A (en) Coagulating cannula
US5423814A (en) Endoscopic bipolar coagulation device
US7854736B2 (en) Surgical instrument and method
US6217575B1 (en) PMR catheter
US6036689A (en) Ablation device for treating atherosclerotic tissues
US5178620A (en) Thermal dilatation catheter and method
US5984920A (en) Rotatable sphincterotome/papillotome and method of use