US20100140149A1 - Modular, Portable Dialysis System - Google Patents
Modular, Portable Dialysis System Download PDFInfo
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- US20100140149A1 US20100140149A1 US12/610,032 US61003209A US2010140149A1 US 20100140149 A1 US20100140149 A1 US 20100140149A1 US 61003209 A US61003209 A US 61003209A US 2010140149 A1 US2010140149 A1 US 2010140149A1
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- external housing
- dialysis system
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- modular dialysis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D61/00—Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltration; Apparatus, accessories or auxiliary operations specially adapted therefor
- B01D61/24—Dialysis ; Membrane extraction
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D61/00—Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltration; Apparatus, accessories or auxiliary operations specially adapted therefor
- B01D61/24—Dialysis ; Membrane extraction
- B01D61/28—Apparatus therefor
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D61/00—Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltration; Apparatus, accessories or auxiliary operations specially adapted therefor
- B01D61/24—Dialysis ; Membrane extraction
- B01D61/30—Accessories; Auxiliary operation
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- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
- G16H20/00—ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance
- G16H20/40—ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to mechanical, radiation or invasive therapies, e.g. surgery, laser therapy, dialysis or acupuncture
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
- G16H40/00—ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices
- G16H40/60—ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices
- G16H40/63—ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for local operation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/12—General characteristics of the apparatus with interchangeable cassettes forming partially or totally the fluid circuit
- A61M2205/121—General characteristics of the apparatus with interchangeable cassettes forming partially or totally the fluid circuit interface between cassette and base
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/35—Communication
- A61M2205/3546—Range
- A61M2205/3569—Range sublocal, e.g. between console and disposable
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2209/00—Ancillary equipment
- A61M2209/08—Supports for equipment
- A61M2209/084—Supporting bases, stands for equipment
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D2313/00—Details relating to membrane modules or apparatus
- B01D2313/20—Specific housing
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D2313/00—Details relating to membrane modules or apparatus
- B01D2313/20—Specific housing
- B01D2313/205—Specific housing characterised by the shape
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D2313/00—Details relating to membrane modules or apparatus
- B01D2313/20—Specific housing
- B01D2313/208—Resilient or flexible housing walls, e.g. bags or foils
Definitions
- U.S. Pat. No. 4,443,333 discloses a portable system for dialyzing blood wherein blood passes through an exchange station with the blood contacting one side of a semipermeable membrane and dialysate contacting the other side of the semipermeable membrane, the system comprising elastic tube means adapted to be connected to a blood source and to return blood thereto for conducting blood past a plurality of stations, a blood clot detector and an air bubble detector in communication with said blood tube means, elastic tube means adapted to be connected to a source of dialysate for conducting dialysate past a plurality of stations, means for measuring and regulating dialysate flow, pressure, temperature and conductivity, means for maintaining the dialysate at a lower pressure than the blood during passage through the exchange station, a single motor means having the output shaft thereof connected to at least two peristaltic pumps one for transporting blood in the elastic blood means and the other for transporting dialysate in the elastic dialysate tube means, mechanism associated with the motor means and the peristaltic pumps
- the bottom side of the first external housing comprises an electrical contact pad and the top side of the second external housing comprises a plurality of electrical pins.
- the bottom side of the first external housing comprises a plurality of electrical pins and the top side of the second external housing comprises an electrical contact pad.
- the controller unit is automatically placed in electrical communication with said reservoir unit when the contact pad is aligned and placed in electrical communication with the plurality of push-pins.
- the controller unit when said first external housing is securely and removably attached to said second external housing, the controller unit is automatically placed in data communication with said reservoir unit.
- the bottom side of the first external housing comprises a first infrared communication port having at least one LED transmitter and at least one LED receiver and the top side of the second external housing comprises a second infrared communication port having at least one LED transmitter and at least one LED receiver.
- the controller unit is automatically placed in data communication with said reservoir unit when the first infrared communication port is aligned and placed in data communication with the second infrared communication port.
- FIG. 5 is a view of the internal structure of the top unit in one embodiment of the present invention.
- FIG. 9 a is a first view of the top surface of the bottom unit with leak channels and leak detectors designated therein;
- FIG. 9 b is a second view of the top surface of the bottom unit with leak channels and leak detectors designated therein;
- non-contact infrared communication ports can be distributed in any functional manner across the top surface of the bottom unit or bottom surface of the top unit. It should further appreciated that any other communication port or structure known to persons of ordinary skill in the art can be implemented herein.
Abstract
Description
- The present invention relies on U.S. Patent Provisional No. 61/109,834, filed on Oct. 30, 2008, for priority. The present invention is also related to U.S. patent application Ser. Nos. 12/575,450, filed on Oct. 7, 2009, 12/575,449, filed on Oct. 7, 2009, 12/355,102, filed on Jan. 16, 2009, 12/355,128, filed on Jan. 16, 2009, 12/351,969, filed on Jan. 12, 2009, 12/324,924, filed on Nov. 28, 2008, 12/210,080, filed on Sep. 12, 2008, 12/238,055, filed on Sep. 25, 2008, 12/237,914, filed on Sep. 25, 2008, 12/249,090, filed on Oct. 10, 2008, and 12/245,397, filed on Oct. 3, 2008. All of the aforementioned applications are herein incorporated by reference.
- The present invention is directed to a dialysis system with improved structural and functional features. In particular, the dialysis system of the present invention is directed to a portable dialysis system with improved modularity, ease of use, and safety features.
- Hemodialysis is used for removing toxic wastes from the human body in cases of renal failure. The patient's blood is temporarily brought outside of the body via tubes and passed through at least one semi-permeable membrane, which may be a group of hollow fibers, in a dialyzer. The semi-permeable membrane separates the blood from a dialysate solution. Impurities from the blood pass through the membrane and into the dialysate solutions, primarily by osmotic pressure. The cleansed blood is then returned to the body.
- Standard dialysis treatment, using an installed apparatus in hospitals, comprises two phases, namely, (a) dialysis, in which toxic substances and scoriae (normally small molecules) pass through the semi-permeable membrane from the blood to the dialysis liquid, and (b) ultrafiltration, in which a pressure difference between the blood circuit and the dialysate circuit, more precisely a reduced pressure in the latter circuit, causes the blood content of water to be reduced by a predetermined amount.
- Dialysis procedures using standard equipment tend to be cumbersome as well as costly, besides requiring the patient to be bound to a dialysis center for long durations. Portable dialysis systems have been developed. U.S. Pat. No. 4,083,777 discloses a hemodialysis system with dialyzer means through which waste impurity-containing blood and a dialysate solution are passed in indirect mass transfer dialyzing relationship for transfer of the waste impurities from the blood to the dialysate solution. The apparatus includes means for transferring waste impurity-containing blood from a patient to said dialyzer means including a flexible resilient tubing pumping section through which blood is pumped and means for returning waste impurity depleted blood to the patient forming a blood flow circuit. Peristaltic pump means are provided with a rotatable pump head assembly including a base member positioned for rotation about a fixed axis with a plurality of circumferentially spaced apart rollers mounted thereon for independent rotation about respective axes parallel to the base member fixed axis.
- U.S. Pat. No. 4,443,333 discloses a portable system for dialyzing blood wherein blood passes through an exchange station with the blood contacting one side of a semipermeable membrane and dialysate contacting the other side of the semipermeable membrane, the system comprising elastic tube means adapted to be connected to a blood source and to return blood thereto for conducting blood past a plurality of stations, a blood clot detector and an air bubble detector in communication with said blood tube means, elastic tube means adapted to be connected to a source of dialysate for conducting dialysate past a plurality of stations, means for measuring and regulating dialysate flow, pressure, temperature and conductivity, means for maintaining the dialysate at a lower pressure than the blood during passage through the exchange station, a single motor means having the output shaft thereof connected to at least two peristaltic pumps one for transporting blood in the elastic blood means and the other for transporting dialysate in the elastic dialysate tube means, mechanism associated with the motor means and the peristaltic pumps for maintaining the dialysate flow at about three times the blood flow, each of the peristaltic pumps having an inner arcuate surface, the blood pump having at least one roller associated with the inner arcuate bearing surface to trap the blood tube means therebetween, the dialysate pump having a single roller associated with said inner arcuate bearing surface to trap said dialysate tube means therebetween, actuation of the peristaltic blood pump causing smooth laminar flow of blood in the blood tube means due to the roller, actuation of the peristaltic dialysate pump causing dialysate flow due to a vacuum generated by the single roller resulting in the deformation and return of the elastic dialysate tube means, and control mechanism operatively connected to the blood leak detector and the air bubble detector and to the motor means and to the dialysate flow, pressure, temperature and conductivity measuring means for selectively stopping the dialysate roller thereby halting movement of dialysate through the dialysate tube means and through the exchange station in response to pressure or temperature or conductivity measurements outside of a preselected range while maintaining blood flow and for simultaneously stopping all the rollers in response to a signal from either the blood leak detector or the air bubble detector to shut down the entire system and halt pumping.
- U.S. Pat. No. 6,168,578 discloses a portable kidney dialysis system that includes a belt with a drain bag mounted thereon. A pump is also mounted on the belt and coupled between a user and the drain bag. The pump is adapted to pump fluid from the user to the drain bag upon the receipt of a drain signal. Further provided is a pressure switch for detecting when the drain bag is full. A control mechanism serves for transmitting the drain signal to the pump only when the means fails to detect that the drain bag is full. A portable dialysis system called System One made by NxStage is another example of a conventional portable hemodialysis system.
- The aforementioned portable dialysis systems suffer from certain disadvantages. First, they are not sufficiently modular, thereby preventing the easy setup, movement, shipping, and maintenance of the systems. Second, the systems are not simplified enough for reliable, accurate use by a patient. The systems' interfaces and methods of using disposable components are subject to misuse and/or errors in usage by patients. For a portable dialysis system to be truly effective, it should be easily and readily used by individuals who are not health-care professionals, with disposable input and data input sufficiently constrained to prevent inaccurate use.
- It is therefore desirable to have a portable dialysis system that has a structural design configured to optimize the modularity of the system, thereby enabling the easy setup, movement, shipping, and maintenance of the system. It is further desirable to have system interfaces, through which patients input data or deploy disposable components, configured to prevent errors in usage and sufficiently constrained to prevent inaccurate use.
- The present invention is directed toward a modular dialysis system comprising a controller unit having a first external housing with a front side, a back side, a left side, a right side, a top side and a bottom side, wherein said front side comprises a door configured to provide access to an internal volume within said controller unit; a reservoir unit having a second external housing with a front side, a back side, a left side, a right side, a top side and a bottom side, wherein said front side comprises a door configured to provide access to an internal volume within said reservoir unit; wherein said bottom side of the first external housing is adapted to securely and removably attach to said top side of the second external housing and wherein, when said first external housing is securely and removably attached to said second external housing, the controller unit is automatically placed in electrical communication with said reservoir unit.
- Optionally, the bottom side of the first external housing comprises an electrical contact pad and the top side of the second external housing comprises a plurality of electrical pins. Optionally, the bottom side of the first external housing comprises a plurality of electrical pins and the top side of the second external housing comprises an electrical contact pad. The controller unit is automatically placed in electrical communication with said reservoir unit when the contact pad is aligned and placed in electrical communication with the plurality of push-pins.
- Optionally, when said first external housing is securely and removably attached to said second external housing, the controller unit is automatically placed in data communication with said reservoir unit. The bottom side of the first external housing comprises a first infrared communication port having at least one LED transmitter and at least one LED receiver and the top side of the second external housing comprises a second infrared communication port having at least one LED transmitter and at least one LED receiver. The controller unit is automatically placed in data communication with said reservoir unit when the first infrared communication port is aligned and placed in data communication with the second infrared communication port.
- Optionally, the internal volume within said controller unit houses a manifold, a hook, and a guard encircling the manifold. The door configured to provide access to the internal volume within said controller unit has an internal surface and said internal surface comprises a plurality of pump shoes, a latch, and casing with sides that protrude into said internal volume when said door is closed. When the door is closed, said latch mechanically engages said hook. The modular dialysis system further comprises a controller configured to actuate a motor to apply a motive force to said hook and said application of motive force causes said door to be closed with a force in a range of 90 to 110 lbs. The modular dialysis system further comprises a mechanical release button having a first state and a second state, wherein, in said first state, the button is capable of mechanically engaging said hook and wherein, in said second state, the button is not capable of mechanically engaging said hook.
- In another embodiment, the present invention is directed to a modular dialysis system comprising a controller unit having a first external housing with a front side, a back side, a left side, a right side, a top side and a bottom side, wherein said front side comprises a door configured to provide access to an internal volume within said controller unit; a reservoir unit having a second external housing with a front side, a back side, a left side, a right side, a top side and a bottom side, wherein said front side comprises a door configured to provide access to an internal volume within said reservoir unit, wherein said top side has an angled surface with a plurality of channels in fluid communication with at least one leak detector; and wherein said bottom side of the first external housing is adapted to securely and removably attach to said top side of the second external housing.
- Optionally, the bottom side of the first external housing comprises an electrical contact pad and the top side of the second external housing comprises a plurality of electrical pins. The controller unit is automatically placed in electrical communication with said reservoir unit when the contact pad is aligned and placed in electrical communication with the plurality of push-pins. The bottom side of the first external housing comprises a first infrared communication port having at least one LED transmitter and at least one LED receiver and the top side of the second external housing comprises a second infrared communication port having at least one LED transmitter and at least one LED receiver. The controller unit is automatically placed in data communication with said reservoir unit when the first infrared communication port is aligned and placed in data communication with the second infrared communication port.
- Optionally, the internal volume within said controller unit houses a hook and the door configured to provide access to the internal volume within said controller unit has an internal surface that comprises a latch. The modular dialysis system further comprises a controller configured to actuate a motor to apply a motive force to said hook in response to a user input and said application of motive force causes said door to be closed with a force in a range of 90 to 110 lbs. The modular dialysis system further comprises a mechanical release button having a first state and a second state, wherein, in said first state, the button is capable of mechanically engaging said hook and wherein, in said second state, the button is not capable of mechanically engaging said hook.
- These and other embodiments will be described in more detail in the Detailed Description section in relation to the Drawings.
- Embodiments of the present invention are described in greater detail with respect to the following drawings:
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FIG. 1 is a front view of the dialysis system of the present invention; -
FIG. 2 is view of the dialysis system showing the modularity of the system; -
FIG. 3 is a view of the back of the dialysis system, with the door open; -
FIG. 4 is a front view of one embodiment of the dialysis system with an open door and U-shaped latch; -
FIG. 5 is a view of the internal structure of the top unit in one embodiment of the present invention; -
FIG. 6 is a drawing of a component in a scale-based fluid balance implemented in the present invention; -
FIG. 7 a is a side perspective view of a reservoir with an integrated scale; -
FIG. 7 b is a side perspective view of a flexure assembly; -
FIG. 8 is a front view of an exemplary graphical user interface implemented in the present invention; -
FIG. 9 a is a first view of the top surface of the bottom unit with leak channels and leak detectors designated therein; -
FIG. 9 b is a second view of the top surface of the bottom unit with leak channels and leak detectors designated therein; -
FIG. 9 c is a front view of the bottom unit with leak channels and leak detectors designated therein; -
FIG. 10 is a side of an embodiment of the dialysis machine with a bar code reader; -
FIG. 11 a is schematic of one embodiment of the door assembly; -
FIG. 11 b is a schematic of one embodiment of the door release; -
FIG. 12 are drawings depicting the top of the dialysis system with a modular, mobile workspace; and -
FIG. 13 is a side perspective view of one embodiment of a latch attached to an upper unit of the portable dialysis system; -
FIG. 14 is a first side perspective view of one embodiment of a base unit of the portable dialysis system with a matching latching mechanism; -
FIG. 15 is a second side perspective view of one embodiment of a base unit of the portable dialysis system with a matching latching mechanism; -
FIG. 16 is a top view of electrical and communication connections implemented in one embodiment of the portable dialysis system; -
FIG. 17 a is a top view of one embodiment of the portable dialysis system with exemplary dimensions denoted; -
FIG. 17 b is a front view of one embodiment of the portable dialysis system with exemplary dimensions denoted; -
FIG. 18 a is a view of one embodiment of the base unit with receiving cavities and alignment pins; and -
FIG. 18 b is a view of one embodiment of the top unit with footing pads. - While the present invention may be embodied in many different forms, for the purpose of promoting an understanding of the principles of the invention, reference will now be made to the embodiments illustrated in the drawings and specific language will be used to describe the same. It will nevertheless be understood that no limitation of the scope of the invention is thereby intended. Any alterations and further modifications in the described embodiments, and any further applications of the principles of the invention as described herein are contemplated as would normally occur to one skilled in the art to which the invention relates.
- “Duration” and variations thereof refer to the time course of a prescribed treatment, from initiation to conclusion, whether the treatment is concluded because the condition is resolved or the treatment is suspended for any reason. Over the duration of treatment, a plurality of treatment periods may be prescribed during which one or more prescribed stimuli are administered to the subject.
- “Period” refers to the time over which a “dose” of stimulation is administered to a subject as part of the prescribe treatment plan.
- The term “and/or” means one or all of the listed elements or a combination of any two or more of the listed elements.
- The terms “comprises” and variations thereof do not have a limiting meaning where these terms appear in the description and claims.
- Unless otherwise specified, “a,” “an,” “the,” “one or more,” and “at least one” are used interchangeably and mean one or more than one.
- For any method disclosed herein that includes discrete steps, the steps may be conducted in any feasible order. And, as appropriate, any combination of two or more steps may be conducted simultaneously.
- Also herein, the recitations of numerical ranges by endpoints include all numbers subsumed within that range (e.g., 1 to 5 includes 1, 1.5, 2, 2.75, 3, 3.80, 4, 5, etc.). Unless otherwise indicated, all numbers expressing quantities of components, molecular weights, and so forth used in the specification and claims are to be understood as being modified in all instances by the term “about.” Accordingly, unless otherwise indicated to the contrary, the numerical parameters set forth in the specification and claims are approximations that may vary depending upon the desired properties sought to be obtained by the present invention. At the very least, and not as an attempt to limit the doctrine of equivalents to the scope of the claims, each numerical parameter should at least be construed in light of the number of reported significant digits and by applying ordinary rounding techniques.
- Notwithstanding that the numerical ranges and parameters setting forth the broad scope of the invention are approximations, the numerical values set forth in the specific examples are reported as precisely as possible. All numerical values, however, inherently contain a range necessarily resulting from the standard deviation found in their respective testing measurements.
- The present invention is directed toward a dialysis unit that is modular and portable, with improved functionality. Referring to
FIGS. 1 and 2 , in one embodiment, thedialysis system top unit reservoir top unit graphical user interface door top unit clasp 105 used to detachably affix adialyzer 103. To a second side of thetop unit cartridge locking base 104, 204 used to detachably affix asorbent cartridge 107. It should be appreciated that theclasp 105,hemofilter 103, sorbent cartridge locking base 104 andsorbent cartridge 107 can be positioned on the same side of thetop unit 101, as shown inFIG. 3 . In either case, the bottom unit has a sufficiently larger area relative to the top unit such that shelves are formed on either side of the top unit to hold the sorbent cartridge, to hold an infusate jar, to capture any spillage, and/or to channel any leaks into a leak detector. - Between the
dialyzer 103 anddoor 110 are anti-coagulant pumps in the form of syringe pumps 190. Optionally, thetop unit 101 can comprise abottle holder 190 that has a spiked base to receive a bottle, top-down, within the bottle holder housing. Infusion lines are connected to the inlet of the blood pump, outlet of the blood pump, or outlet of the dialyzer (blood side). The infusion lines could also ‘thread’ through air bubble detectors to sense if/when the anti-coagulant is emptied or blocked. - The dialysis system of the present invention achieves functional and operational parameters that represent a substantial improvement over the prior art. The top unit is in the range of approximately 20-40 pounds, and more particularly 30 pounds, and the bottom unit is in the range of approximately 15-30 pounds, and more particularly 22 pounds, thereby weighing less than prior art systems. The top unit is in the range of approximately 1 to 4 cubic feet, and more particularly 2.3 cubic feet, and the bottom unit is in the range of approximately 1 to 4 cubic feet, and more particularly 2.8 cubic feet, thereby having a smaller volume than prior art systems.
- In one embodiment, referring to
FIG. 17 , thetop unit 1701, which comprises the user interface and controller, has the same depth, but a different length and height than thebase unit 1702, which comprises a reservoir integrated with a scale. In this exemplary embodiment, both thetop unit 1701 andbottom unit 1702 have a depth D in the range of 10 to 30 inches, more preferably approximately 19 inches. In this exemplary embodiment, thetop unit 1701 has a length Lt in the range of 6 to 20 inches, more preferably approximately 14 inches, while the bottom unit has a length Lb in the range of 14 to 40 inches, more preferably 27 inches. In this exemplary embodiment, thetop unit 1701 has a height Ht in the range of 7 to 21 inches, more preferably approximately 14.5 inches, while the bottom unit has a height Hb in the range of 3 to 11 inches, more preferably 7 inches. - The
base unit 1702 may further be defined by twoshoulders 1704, each extending outward, along the length of thebase unit 1702, from the sides of a centrally positionedtop unit 1701. The top unit is preferably positioned in the center of thebase unit 1702, as measured by length Lb. Accordingly, theshoulder 1704 can be defined has having a length in the range of 4 inches to 10 inches, more preferably approximately 7 inches. Extending upward from the surface of thebase unit 1702, whereshoulders 1704 physically meettop unit 1701, is alip 1703 that defines a surface upon whichtop unit 1701 is aligned and placed. Thelip 1703 is contiguous around the base of thetop unit 1701, having the same length and depth as thetop unit 1701, with a height defined as the difference between Ht2 and Ht. In one embodiment, the lip height is in the range of 0.1 to 3.5 inches, more preferably 0.6 inches. The overall height of the system, Ht3, is in the range of 10 to 35 inches, more preferably 22 inches. - The external housing structures defining the
top unit 1701 andbase unit 1702 may be characterized as rectangular parallelpipeds, cuboids, or boxes, each with four sides, a top, and a bottom. In an exemplary embodiment, for both thetop unit 1701 andbase unit 1702, two of the four sides, each having an exterior and interior surface, have the same height, length, and depth, while the top and bottom structures, each having an exterior and interior surface, have the same height, length, and depth. - It should be appreciated that the system configuration shown in
FIGS. 1 , 2, 17 a, and 17 b is exemplary and not limiting. For example, shown inFIG. 3 , thetop unit 301 may be positioned on one side of the base unit 302 (creating an asymmetric base), as opposed to being centrally positioned on top of thebase unit 302 relative to the overall length of the base unit 302 (creating a symmetric base). While placement of thetop unit 301 to one side of thebase unit 302 has the advantage of placing all tubing connections and consumables on the same side of the system,sorbent cartridge 317 anddialyzer 313 are unnecessarily crowded together, making the machine more difficult to use. - The dialysis system uses less water than prior art systems. Conventional systems use approximately 120 liters per treatment. In one embodiment, the present systems uses between 3 and 8 liters, and more particularly between 5 and 6 liters. Furthermore, the system does not require a home drain, supply connection, or separate outlet to address excess water.
- Additionally, in one embodiment, the present invention uses a multi-pass sorbent system, as disclosed in XCORP212 and incorporated herein by reference. Accordingly, the system does not require a separate purified water input with a reverse osmosis system and, instead, can use regular tap water that is then purified using the sorbent system.
- Furthermore, the system design is more compact, with low power requirements (only 300 at peak and 50 to 100 W during operation), no separate fluid bags required for priming or travel, and integrated pumps. The device operates using a blood flow range of 20-600 Qb (ml/min), a dialysate flow of 50-500 Qd (ml/min). The volumetric accuracy is also precise at less than +/−30 ml/hr.
- As demonstrated in
FIG. 2 , the dialysis system is modular. In one embodiment, thetop unit 201 can be physically separated from thebottom unit 202. Thetop unit 201 contains the primary electronics of the system, including the graphical user interface, controllers, and pumps, integrally formed into a self-contained housing. The larger,bulkier bottom unit 202 contains thereservoir 222. Separation of the system electronics from the reservoir allows the portable dialysis system to be separated into multiple units for installation, service, and travel, with each subunit being easily handled, packaged and carried. The design specifically sizes components for shipping via UPS or other door to door carriers. It further provides flexibility in product growth. For example, if improvements are made to the controller unit or, separately, to the reservoir (such as reducing fluid volume or a change in volume scale measurement), an existing customer need only upgrade one of the two component parts, not both. Similarly, if only one of the two components breaks (e.g. the pump burns out), a customer need only send in one for repair or purchase one of the two components. - To enable the above described modularity, embodiments of the present invention employ a latching mechanism that, in a first configuration, securely attaches the
bottom unit 202 to thetop unit 201 and can be manipulated to removably detach thebottom unit 202 from thetop unit 201. Even though the two systems could be simply stacked atop each other, without a latch, the presence and use of a latch reduces the likelihood of an accidental disconnection. Furthermore, when latched together the device is easier to move. The latch mechanism preferably uses no tools and is simply achieved using a male/female mating connections present on the top component and bottom component. Further preferably, the latch mechanism is designed to ensure solid alignment between the top and bottom components, thereby enabling the use of an electronic components (such as exposed electronic connectors on the bottom of the top unit and top of the bottom unit as further described below) which, when the units are properly aligned, automatically come into contact and complete a power circuit. This permits the use of a single power supply and simple connection/disconnection. - Referring to
FIG. 14 , thebottom unit 1402 has foursides top surface 1406, and areservoir 1422 accessible viafirst side 1405 d. Thebottom unit 1402 further comprises a plurality of latch mating structures 1420 on itstop surface 1406. In one embodiment, the present invention comprises twolatch mating structures bottom unit 1402, are centrally positioned to ensure even weight distribution. The firstlatch mating structure 1420 a is preferably positioned a distance equal to one third of the width of thebottom unit 1402, as measured fromside 1405 d. The secondlatch mating structure 1420 b is preferably positioned a distance equal to one third of the width of thebottom unit 1402, as measured fromside 1405 b. - The latching mechanisms, as shown in
FIG. 15 , comprise ametal frame 1501 that is securely fastened using, for example, a bolt, screw, orother fastener 1502, to the top surface of thebottom unit 1505. Theframe 1501 supports a protusion orelongated member 1503 that can flexibly insert into, and be removed from, a corresponding latch. - To securely and removably attach the bottom unit to the top unit, the top unit comprises complementary mechanical sliding latches, which are securely attached to the base of the top unit. In one embodiment, the base of the top unit comprises a first latch that is preferably positioned in the center of top unit, relative to the length of the top unit, and a distance equal to one third of the width of the top unit, as measured from a first side. The base also comprises a second latch that is preferably positioned in the center of top unit, relative to the length of the top unit, and a distance equal to one third of the width of the top unit, as measured from a second side, which is opposite and parallel to the first side.
- As shown in
FIG. 13 , the top unit comprises alatch 1300 with a sliding metalflat base 1315.Rails 1330 are slidably engaged with the bottom surface of the top unit, which has mating members to hold therails 1330 in place. Thelatch 1300 has two latchingtabs 1315 which are adapted to slide into, and out of, mating structures physically attached to the top surface of thebase unit 1406. -
Latches 1300, attached to the top unit, mate withlatch mating structures bottom unit 1406. In operation, when the slidinglatch 1300 is in a first position, the top unit will not effectively fit on top of, or align with, the base unit because the slidinglatch 1300 will not properly physically mate withlatch mating structures base unit 1406, the sliding latches are moved within the member holding structure positioned on the bottom of the top unit and placed into a second position. - In the second position, the handle of the
latch 1311 will protrude, thereby moving thetabs 1315 away from thelatch mating structures FIGS. 18 a and 18 b, thetop unit 1801, which has slidinglatches 1880, is aligned to thebottom unit 1802 by four small rubber feet, or footing pads, 1840 on the bottom of thetop unit 1801, which are configured or adapted to snugly and securely fit into four cavities orpockets 1830 located proximate to each corner on the top of thebottom unit 1802. Additionally, thetop unit 1801 can be accurately aligned to thebottom unit 1802 usingalignment pins 1860, or protusions, on the top surface of thebase unit 1802, which are configured or adapted to securely and snugly fit into correspondingcavities 1890 on the bottom surface of thetop unit 1801. The bottom unit also haslatch mating structures 1863, as described above. - Aligning the
rubber footings 1840 into thecavities 1830 and thepins 1860 into thecavities 1880 ensures that latches 1880 on thetop unit 1801 can be readily aligned and latched to thelatch matching structures 1863 without excessive trial and error. Once aligned, thelatch 1880 is mated with thelatch mating structures 1863 by sliding thelatches 1880 into thelatch mating structures 1863, thereby creating a tight fit between the two units. Referring back toFIGS. 13 and 14 , to unlatch, latch handles 1311 are pulled or otherwise manipulated, thereby releasingtabs 1315 from thebase unit slots - Furthermore, to enable the above described modularity, embodiments of the present invention also employ an electrical and communication connection mechanism that, in a first configuration, securely establishes electrical communication and/or data communication connection between the bottom unit and the top unit and, in a second configuration, terminates an electrical communication and/or data communication connection between the bottom unit to the top unit.
- Referring to
FIG. 16 , the electrical connections between the top and bottom units are created when the top unit is placed on the bottom unit. These connections are made through a non-contactinfrared communications port 1603 and a push-pin power port 1603, which are integrally formed intoplates 1602 and securely attached usingfasteners 1601 to the top surface of thebottom unit 1605. It should be appreciated that the bottom surface of the top unit would then comprise, in proper alignment with the push-pins, an electrical contact pad. It should further be appreciated that the location of the push-pins and contact pads can be reversed, thereby placing the push-pins on the bottom surface of the top unit and the contact pad on the top surface of the bottom unit. - In one embodiment, a high current power connection is created by placing six spring loaded pins into electrical contact with contact pads, which are integrated into the bottom surface of the top unit. Three pins are for +24 volt DC current and three pins are for ground. In one embodiment, the pins or probes have the following characteristics: a) minimum center of 0.175 inches, b) current rating of 15 amps (continuous), c) spring force in the range of 6.2 oz to 9.0 oz at 0.06 inches to 0.067 inches of travel, d) typical resistance of less than 10 mΩ, e) maximum travel in the range of 0.09 to 0.1 inches, f) working travel in the range of 0.06 to 0.067 inches, g) barrel made of nickel/silver and gold plated, h) stainless steel spring (optionally gold plated), i) plunger made of full-hard beryllium copper and gold plated, and j) optionally a stainless steel bias ball. The spring force of the pins assists in preventing breakage by absorbing bending or other contortions. It should be appreciated that the term electrical pins represents any protusion capable of transmitting electrical power and electrical contact paid represents any surface capable of receiving an electrical pin.
- The non-contact
infrared communication port 1603 employs two LED transmitters and two LED receivers which align to, and communicate with, two LED transmitters and two LED receivers on the bottom surface of the top unit. The distance between the transmit and receive ports is less than 0.3 inches. On both the top surface of the bottom unit and bottom surface of the top unit, the four LED units are divided into two pairs, a control pair (comprising one transmitter and one receiver) and one safety pair (comprising one transmitter and one receiver). These ports are placed in data communication when the top and bottom units are properly aligned. In one embodiment, the LED transmitters are high speed infrared emitting diodes, 870 nm, made of GaAlAs double hetero technology. The LED transmitters are high speed diodes having the following characteristics: a) extra high radiant power, b) low forward voltage, c) suitable for high pulse current operation, d) angle of half intensity of approximately 17 degrees, e) peak wavelength of approximately 870 nm, f) reverse voltage of approximately 5V, g) forward current of approximately 100 mA, h) a peak forward current of approximately 200 mA, i) surge forward current of approximately 0.8 A, j) power dissipation of approximately 190 mW) junction temperature of approximately 100 degrees Celsius, and l) an operating temperature range of −40 to 85 degrees Celsius. It should be appreciated that the non-contact infrared communication ports can be distributed in any functional manner across the top surface of the bottom unit or bottom surface of the top unit. It should further appreciated that any other communication port or structure known to persons of ordinary skill in the art can be implemented herein. - In one embodiment, the LED receivers are high speed silicon photodiodes with extra fast response times, radiant sensitive area of approximately 0.25 mm2 and an angle of half sensitivity of approximately 15 degrees.
- The LED receivers have the following characteristics: a) reverse voltage of approximately 60V, b) power dissipation of approximately 75 mW, c) junction temperature of approximately 100 degrees Celsius, d) an operating temperature range of −40 to 85 degrees Celsius, e) forward voltage of approximately 1V, f) minimum breakdown voltage of 60V, and g) diode capacitance of approximately 1.8 pF.
- Referring back to
FIGS. 1 , 2, and 3, atop thecontroller unit handles useable shelf top unit - Referring to
FIG. 5 , in one embodiment, thetop unit 501 comprises an internal metal casing, frame orhousing 510 within which, and to which, the electronics, controller, and other top unit components are contained. Theinternal casing 510 comprises a horizontalprotruding arm 507 that extends to the back side of thetop unit 501. The substantially horizontaltop shelf 505 comprises at least onehandle 520 that is integrally formed into thetop shelf structure 505, abase bracket 530, and avertical arm 506, thereby creating a single, contiguous metal or molded plastic piece. Thebase bracket 530 is securely attached to theinternal casing 510 at the front of thetop unit 501 and thevertical arm 506 is securely attached to theprotruding arm 507 atpoint 508 using screws. By securely attaching theshelf 505 and handle 520 structure to theinternal casing 510 of thetop unit 501, one avoids potential damage or breakage that would normally occur by placing large weight loads at the point of connection between a handle and an external or outside housing of the top unit. - Also attached to the internal frame or
casing 510 is ametal door 562, withhinges 565, which forms the internal frame ofdoor 110, shown inFIG. 1 .Door 562 is securely attached to plate 561 which is part ofinternal frame 510.Structures Protusion 583, which extends from the back offrame 510, is used to connect various electronic components, including a power entry module andUSB connections 582. - The top of the controller unit, or
shelf 505, is flat and has side-walls making it ideal for storage of supplies or a temporary working surface. Referring toFIG. 12 , in one embodiment,disposables 1206 for use in the system are shipped in packaging preassembled on atray 1205. Thetray 1205 is placed on top of thecontroller unit 1201 workspace, thereby permitting easy access to, and management of, the required disposables, which is of particular importance for home users. Thecontroller unit 1201 is waterproof rated, so that, in case of a liquid spill, it should not seep into and damage thetop controller unit 1201. - Another structural feature of the
controller unit 1001 is shown inFIG. 10 . Preferably, theunit 1001 has a built-in exposed reader, such as a bar code reader orRFID tag reader 1005, which can be used to read codes or tags on the disposable components. Operationally, a user would preferably swipe all of the codes/tags on the disposable components by the reader. Prompting the user can be effectuated through an initial GUI dialysis setup step which instructs the user to swipe each disposable component passed the reader. - Upon doing so, the reader obtains identifying information about the disposable, transmits that identifying information to an internal table stored in memory, compares the identifying information to the contents of the internal table, and verifies (or does not verify) that the correct disposable components (particularly additives used in the dialysate) are present. The contents of the internal table can be generated by manual input of the identity and amount of the disposables or by remote access to a prescription that details the identity and amount of the disposables. This verification step has at least two benefits. The first is to ensure that the user has, in his or her possession, all of the required components and the second is to ensure that the correct components are being used (not counterfeit or unsuitable disposables).
- In another embodiment, the
reader 1005 mounted on the side of the top unit is a specialized multi-function infrared camera that, in one mode, provides the ability to read bar codes and, in another mode, detects a level change in the infusate container. The camera emits an infrared signal that reflects off fluid level. The reflected signal is received by the camera's infrared receiver and processed, using a processor, to determine the location of the meniscus of the fluid level. In one embodiment, the camera can determine and monitor a change in the fluid level to a resolution of 0.02 mm. In one embodiment, the camera is a 1.3 megapixel single-chip camera module with one or more of the following characteristics: a) 1280 H×1024V active pixels, b) 3.0 μm pixel size, c) ⅓ inch optical format, d) RGB Bayer color filter array, e) integrated 10-bit ADC, f) integrated digital image processing functions including defect correction, lens shading correction, image scaling, demosaicing, sharpening, gamma correction, and color space conversion, g) embedded camera controller for automatic exposure control, automatic white balance control, and back level compensation, h) programmable frame rate and output derating functions, i) up to 15 fps SXGA progressive scan, j) low power 30 fps VGA progressive scan, k) 8-bit parallel video interface, 1) two-wire serial control interface, m) on-chip PLL, n) analog power supply from 2.4 to 3.0 V, o) separate I/O power supply, p) integrated power management with power switch, and q) 24 pin shield socket options. In one embodiment, the camera is a 1.3 megapixel camera made by ST Microelectronics, Model No. VL6624/V6624. - The top or bottom unit of the dialysis system also preferably has electronic interfaces, such as Ethernet connections or USB ports, to enable a direct connection to a network, thereby facilitating remote prescription verification, compliance vigilance, and other remote servicing operations. The USB ports permit direct connection to accessory products such as blood pressure monitors or hematocrit/saturation monitors. The interfaces are electronically isolated, thereby ensuring patient safety regardless of the quality of the interfacing device.
- The front of the top unit has a
graphical user interface 114 that provides for a simple user interface with thesystem 100. In a home setting it is important that the device be easy to use. Maximal use of colors and the touch screen is ideally suited for the application. The touch screen allows multiple user input configurations, provides multiple language capability, and can be readily seen at night (particularly with brightness controls and night-vision colors). The GUI further includes a feature for the automatic closing, opening, and locking of the door during operation. In one embodiment, the GUI opens the door to a first latch position and then a user must press a physical door-open button to fully open the door. In another embodiment, the device has a manual override which permits the user to open the door (e.g. by pressing the open door button twice or with extra force) to manually open the door. Referring toFIG. 8 , preferably, proximate to theGUI 800, is a singlemechanical button 805, with lighted visual indication, that, if activated, provides a central stop button with a common function (such as stopping the system) regardless of the state of operation. - Referring to
FIG. 1 , thereservoir system 102 has adoor 118 which, when pulled, slides thereservoir 122 out to permit access to the reservoir. The reservoir volume is monitored by a scale system. The scale-basedfluid balance 600, depicted inFIG. 6 and more particularly inFIGS. 7 a and 7 b, is integrally formed with the reservoir and provides accurate fluid removal data and enables accurate balance calculations, thereby preventing hypotension and other ailments caused from fluid imbalances. Integrating the scale with the reservoir and enclosing them completely provides for a more robust system. - Referring to
FIG. 7 a, theinternal structure 700 of the reservoir system is shown. A metallicinternal frame 720 comprises twosides 721, a back 722, and openfaced front 723, and abase 724. The internal structure or frame is shown without the external housing, as depicted aselement 102 inFIG. 1 . Ascale 718 is integrated into the reservoirinternal structure 700. Thebottom surface 715 of thescale 718 comprises a metal surface or pan that, together with the rest of thescale 718, is suspended from the external reservoir housing (shown as 102 inFIG. 1 ) by fourflexures 705. Below thebottom surface 715 of the scale is preferably situated a heating pad, such as a square, rectangular, circular, or other shaped surface capable of incurring a temperature increase and conducting the increased temperature, as heat, to surface 715. Aconductivity coil 770, capable of exerting a field and using changes in that field to measure conductivity, is integrated intobase surface 715. Accordingly, when a reservoir bag (not shown) is placed onbottom surface 715, it can be heated by a heating pad and, because it is in contact withcoil 770, its conductivity can be monitored. - The internal surfaces of the
sides 721 comprise a plurality of rails, elongated members, or protusions 719 that serve to secure, hold, encase or attach to a disposable reservoir bag mounting surface, such as a plastic sheet, 710 to which a reservoir bag can be attached. Specifically, a reservoir bag positioned onsurface 715 can have an outlet attached toconduit 771 integrated intosheet 710. Mounted in each of the four corners of thescale surface 718 areflexures 705 with each one comprising a hall sensor and magnet. - Referring to
FIG. 7 b, theflexure 705 comprises a plurality of attachment points 761 where the flexure is secured to the external reservoir housing. The flexure further comprisesmagnetic bodies 762, such as two magnets, and ahall sensor 764. Thebase 767 of theflexure 705 is attached to thetop surface 715 ofscale 718. As thescale 718 displaces due to the application of a weight load (e.g. when the reservoir bag fills with dialysate the bag presses onsurface 715, thereby pullingscale 718 downward), theflexure 705, which is connected to the scale at one end and the external housing at another end, will flex and themagnet 762, mounted on the one end of theflexure 705, will track that change by virtue of changes to the magnetic field generated by themagnetic body 762. Thehall sensor 764 detects changes in the magnetic field strength. One of ordinary skill in the art would understand how to translate this sensed magnetic field change into a measure of the applied weight load. - The placement of disposable components, such as the
dialyzer 103,sorbent cartridge 107, and infusate, in a manner that is external to the system but easily accessible permits the use of multiple sized sorbent cartridges, dialyzers, and infusate mixes, thereby giving greater flexibility to the use and applicability of the system. Referring toFIGS. 3 , and 9, the disposable components, particularly the fully disposable blood and dialysate circuits, are prepackaged in a kit (which includes dialyzer, manifold, tubing, reservoir bag, ammonia sensor, and other components) and then used by opening thefront door 303 of the top unit 301 (as discussed above), installing thedialyzer 313 and installing the manifold 304 in a manner that ensures alignment against non-disposable components such as pressure, sensors, and other components. A plurality ofpump shoes 305 integrated into the internal surface of thefront door 303 makes loading of disposable components easy. The manifold only needs to be inserted and no pump tubing needs to be threaded between the rollers and shoes 305. This packaged, simple approach enables easy disposables loading and cleaning of the system. It also ensures that the flow circuitry, shown inFIG. 11 , is properly configured and ready for use. In operation, thetop unit 301 is attached to thebottom unit 302 withreservoir 322. - The front door opens widely (approximately 100 degrees), for loading the disposables. Having a wide opening facilitates manifold loading and easy cleaning of the faces of the machine and inside of the door. Having the door close and cover the moving parts of the device makes it safer and more robust, which is particularly important for home use. Additionally, having the front door house the display saves space and re-enforces the important point that the device is not to be operated unless the disposables are in place and the door is closed. The door provides the necessary occlusion force on the manifold and its pump segments. The door also contains a touch screen, audio alarm, and manual stop button in the face of the door.
- In one embodiment, the door is held in a fully closed position by an electric stepper motor. This motor is operated via the user interface and, in particular, by a user pressing a button when the door is ready to be fully closed or opened. To ensure proper pressure is placed on the manifold structures by the door and pump shoes, it is preferred to have an electronic mechanism by which the door is closed and sufficient closing door force is generated. In one embodiment, a closing door force of 90 to 110 lbs is generated.
- Referring to
FIG. 11 a, one embodiment of the powerdoor closing mechanism 1100 is shown. Astepper motor 1106 is mechanically engaged with alead screw 1116, such that, when actuated by a controller, thestepper motor 1106 causes thelead screw 1116 to turn and, consequently, to causerod 1118 to apply a motive force to a hook. The hook, located undermember 1140, serves to latch onto U-latch 1130 and, when pulled, turned, or otherwise moved inward towardstepper motor 1106, pull the U-latch 1130 further closed, thereby applying the requisite closing door force. The hook is physically engaged withrod 1118 and can be manipulated to pull the U-latch 1130 tightly closed or to loosely engage with the U-latch 1130. The power closing system is mounted and kept in proper orientation by mountingbrackets 1105. - Operationally, a user closes the door sufficiently to engage the U-latch 410 on the door with the
hook 450 inside the internal volume of the controller unit, as shown inFIG. 4 . A user then indicates to the portable dialysis machine a desire to close the door, preferably through a mechanical button or graphical user interface icon, which, when pressed, sends a signal to a controller that, in turn, actuates thestepper motor 1106. Thestepper motor 1106 applies a motive force to thehook 450, which then pulls the engaged U-latch 1130, 410 tightly closed. In one embodiment, a controller monitors the torque force being applied by the motor and, when it reaches a pre-defined limit, deactivates the stepper motor. In another embodiment, a hall device positioned proximate to the lead screw senses the extension of the lead screw and determines the extent of movement of the screw. If the screw has sufficiently moved in the direction of creating greater closing door force, the hall sensor transmits a signal to the controller to deactivate the motor. Alternatively, the sensor constantly transmits a signal indicative of the extension of the screw, which is then interpreted by the controller to determine if sufficient motive force has been applied, and whether the stepper motor should be deactivated. In any of these embodiments, if the motor over torques, a pre-set distance is exceeded, or the door does not reach its fully closed position in a predetermined time, a controller can actuate the motor to stop and reverse to a fully open state. The controller can also cause a visual and/or auditory alarm to sound. - When a user wishes to open the door, a mechanical button or graphical user interface icon is activated, sends a signal to a controller that, in turn, actuates the
stepper motor 1106 in reverse. The hook then becomes loosely engaged with the U-shaped latch. Amechanical release button 1107 is then pressed to disengage the loosely engaged hook from the U-shaped latch. - In addition to providing the requisite closing force, this power door closing mechanism has several important features. First, it is designed to avoid obstructions from being caught in the door and subject to the powerful door closing force. Referring to
FIG. 4 , the manifold is surrounded by an edge guard which prevents a door latch from engaging with a latch receiver on the top unit if a blockage, such as person's finger or improperly installed disposable, is between the door and the top unit's base plate.Door 405 comprises aninternal surface 406 to which ametallic casing 425 is attached. In one embodiment, the top surface of theinternal surface 406 of thedoor 405 is securely attached to an external surface of thecasing 425. Thecasing 425 is substantially rectangular and defines a cavity with foursides 407 and a base 408 creating an internal volume. The cavity opens toward themanifold structure 430 of thedialysis system 400 and encompasses and surrounds themanifold structure 430 andguard 440, which is preferably a plastic shroud that surrounds themanifold structure 430 at its top and sides. Attached to the surface of the base 408 are the pump shoes 415 and at least oneU-shaped latch 410, which protrudes toward the back plate. Integrated within, and extending out of, the guard is ahook 450 which is configured to securely engage and disengage theU-shaped latch 410. If the door is correctly closed and nothing is caught between the door and the guard, then the U-shaped latch will be mechanically hooked by the power-door lock hook mechanism. If an obstruction is in the door pathway, themetal casing 425 will be unable to extend into the internal volume of the top unit (and encompass the guard) and, therefore, the U-shaped latch will be unable to engage the hook, thereby preventing the mechanical hooking and accidental power closing of the door when an obstruction is in place. - Second, the
mechanical button release 1107 can only be actuated when the power closing door force has been dissipated through the reverse motion of the stepper motor, thereby preventing an accidental release of, and rapid opening of, the door. Referring toFIGS. 11 a and 11 b, when the door is closed and locked, acollar 1150 on thebutton shaft 1107 turns 90 degrees moving a push pin away from the power-door locking hook. Thecollar 1150 is turned by virtue ofrod 1121, which is connected to the collar atpoint 1145 and in mechanical engagement withlead screw 1116. Thecollar 1150 is spring loaded and locked by a small pin solenoid. If the user presses the button when in the locked position the button will move into the machine but, because of the displacement caused by the turning of the collar, will not disengage the hook, thereby preventing the door from opening. If the power is lost or unintentionally terminated, then the pin solenoid will release, allowing the collar to turn back 90 degrees and placing the push-pin in proper alignment. Then when the user presses the button the push pin will contact the power-door hook and release the door latch. This mechanism provides the convenience and safety back up of a mechanical door release without concern that the mechanical door release can accidentally be activated to cause the door to swing open with tremendous force. It should be appreciated that the term “hook” or “latch” should be broadly defined as any protusion or member capable of physically or mechanically engaging with another protusion or member. It should further be appreciated that the term “U-shaped latch” is not limiting and any latching or hooking mechanism, as defined above, can be used. - As discussed above, shelving space formed by the bottom unit and surrounding the top unit employs drainage paths with fluid sensors, in multiple locations internal and external to the device, in order to enable zoned leak detection. Specifically, by building in drainage paths, with optical leak sensors, into the external body of the device, the system captures and routes fluids potentially leaked from the external components (like the sorbent canister) to the optical leak sensors.
- In one embodiment, integrated within the external housings of the bottom unit are at least three different optical leak detectors. Referring to
FIG. 9 a, the top surface ofbottom unit 902 is slightly angled, withcenter 980 raised relative tosides center area 980 tosides Channels 987 encircle the top surface of the bottom unit, extend around the periphery, extend through the center of the top surface, and/or extend through any other portion of the top surface. By virtue of the angled top surface of thebottom unit 902, thechannels 987 are also angled from thecenter 980 to thesides back side 991 tofront surface 990. Theangled channels 987 cause fluids to be directed away from the center and/or back of the system forward and to the sides where leak detectors 988 are positioned and are in fluid communication with thechannels 987. - A first
optical leak detector 988 a is located on the front right corner of the top surface of thebottom unit 902. A secondoptical leak detector 988 b is located on the front left corner of the top surface of thebottom unit 902. Each leak detector is positioned within a well or cavity and comprises an optical sensor, which is located in the side of the well. The optical sensor detects fluids that have drained and/or been channeled to the wells and transmits a detected signal to a controller in the top unit. The detected signal is processed by a processor determine if a leak has occurred. Detected signals are then stored and, if required, the processor causes an alarm or alert to display on the GUI. The well or cavity preferably comprises a rounded base to permit the user to easily wipe the well dry.FIG. 9 b shows a more detailed view of the top surface of thebottom unit 902 withchannels 987 andleak detector 988 a positioned within well 997. - Referring to
FIG. 9 c, at least one additional leak detector is located within thebottom unit 902 and, more particularly inside thereservoir 903, within which ascale 904 is integrated.Channels 905 are integrated into the reservoir structure, such as the internal housing or metal bag holder, and are preferably angled, from one side to the other side or from the center to either side. In one embodiment, the angle is in the range of 1 to 10 degrees and more particularly 3 degrees. A well 910 housing a leak detector is integrated into the reservoir housing and in fluid communication with thechannels 905 in one or both sides of the reservoir housing. If a leak occurs in the disposable bag, fluid will drain to the corner of the metal pan or reservoir housing viachannels 905 and be directed into at least one well with aleak sensor 910. - The drainage paths serve two functions: a) to make sure fluid does not enter the instrument and b) to make sure that a leak is quickly contained and routed to a sensor which can trigger an alert or alarm. Additionally, the device preferably also includes fluid drainage channels leading to wells with optical sensors on the interior of the device. So for instance if there is a leak in the internal reservoir the fluid is routed away from critical components and an optical sensor warns of the leak. Based on the sensor activated, the GUI can present an alarm to the user and can specifically identify the location of the fluid leak. By providing several independent zones of leak detection (several fluid sensors and drainage paths), the instrument can guide the user to find the leak quickly. Having multiple channels and sensors allows the system to partially, automatically, identify the source of the leak and offer graphic assistance, toward remedy of the problem, to the user.
- While there has been illustrated and described what is at present considered to be a preferred embodiment of the present invention, it will be understood by those skilled in the art that various changes and modifications may be made, and equivalents may be substituted for elements thereof without departing from the true scope of the invention. In addition, many modifications may be made to adapt a particular situation or material to the teachings of the invention without departing from the central scope thereof. Therefore, it is intended that this invention not be limited to the particular embodiment disclosed as the best mode contemplated for carrying out the invention, but that the invention will include all embodiments falling within the scope of the appended claims.
Claims (20)
Priority Applications (17)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US12/610,032 US10035103B2 (en) | 2008-10-30 | 2009-10-30 | Modular, portable dialysis system |
US12/751,930 US9199022B2 (en) | 2008-09-12 | 2010-03-31 | Modular reservoir assembly for a hemodialysis and hemofiltration system |
US13/023,490 US8597505B2 (en) | 2007-09-13 | 2011-02-08 | Portable dialysis machine |
US13/726,457 US9358331B2 (en) | 2007-09-13 | 2012-12-24 | Portable dialysis machine with improved reservoir heating system |
US13/852,918 US9308307B2 (en) | 2007-09-13 | 2013-03-28 | Manifold diaphragms |
US14/040,362 US9517296B2 (en) | 2007-09-13 | 2013-09-27 | Portable dialysis machine |
US14/923,904 US9759710B2 (en) | 2008-09-12 | 2015-10-27 | Modular reservoir assembly for a hemodialysis and hemofiltration system |
US15/055,857 US10258731B2 (en) | 2007-09-13 | 2016-02-29 | Manifold diaphragms |
US15/147,639 US10383993B2 (en) | 2007-09-13 | 2016-05-05 | Pump shoe for use in a pumping system of a dialysis machine |
US15/341,953 US10596310B2 (en) | 2007-09-13 | 2016-11-02 | Portable dialysis machine |
US15/666,821 US10670577B2 (en) | 2008-10-30 | 2017-08-02 | Modular reservoir assembly for a hemodialysis and hemofiltration system |
US15/985,869 US10758868B2 (en) | 2008-10-30 | 2018-05-22 | Methods and systems for leak detection in a dialysis system |
US16/286,923 US10857281B2 (en) | 2007-09-13 | 2019-02-27 | Disposable kits adapted for use in a dialysis machine |
US16/455,798 US11318248B2 (en) | 2007-09-13 | 2019-06-28 | Methods for heating a reservoir unit in a dialysis system |
US16/788,667 US11071811B2 (en) | 2007-09-13 | 2020-02-12 | Portable dialysis machine |
US16/856,391 US11169137B2 (en) | 2008-10-30 | 2020-04-23 | Modular reservoir assembly for a hemodialysis and hemofiltration system |
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---|---|---|---|---|
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US20110093294A1 (en) * | 2009-10-16 | 2011-04-21 | Baxter International Inc. | Peritoneal dialysis optimized using a patient hand-held scanning device |
US20120181331A1 (en) * | 2011-01-18 | 2012-07-19 | Fresenius Medical Care Deutschland Gmbh | Method for querying a specification feature of a medical technical functional means, a medical technical functional means, a medical device and a control unit |
US20120181296A1 (en) * | 2009-09-29 | 2012-07-19 | Andreas Syfonios | Housing with closure flap |
US20120197185A1 (en) * | 2011-02-02 | 2012-08-02 | Kai Tao | Electromechanical system for IV control |
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US8608658B2 (en) | 2002-01-04 | 2013-12-17 | Nxstage Medical, Inc. | Method and apparatus for machine error detection by combining multiple sensor inputs |
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WO2014105267A1 (en) * | 2012-12-24 | 2014-07-03 | Fresenius Medical Care Holdings, Inc. | Load suspension and weighing system for a dialysis machine reservoir |
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WO2014151322A1 (en) | 2013-03-14 | 2014-09-25 | Fresenius Medical Care Holdings, Inc. | Universal portable machine for online hemodiafiltration using regenerated dialysate |
US8945936B2 (en) * | 2011-04-06 | 2015-02-03 | Fresenius Medical Care Holdings, Inc. | Measuring chemical properties of a sample fluid in dialysis systems |
WO2016039837A1 (en) * | 2014-09-12 | 2016-03-17 | Easydial, Inc. | Portable hemodialysis machine and disposable cartridge with dialysis reservoir level sensor |
US9308307B2 (en) | 2007-09-13 | 2016-04-12 | Fresenius Medical Care Holdings, Inc. | Manifold diaphragms |
US9354640B2 (en) | 2013-11-11 | 2016-05-31 | Fresenius Medical Care Holdings, Inc. | Smart actuator for valve |
US9360129B2 (en) | 2009-01-12 | 2016-06-07 | Fresenius Medical Care Holdings, Inc. | Valve system |
US9358331B2 (en) | 2007-09-13 | 2016-06-07 | Fresenius Medical Care Holdings, Inc. | Portable dialysis machine with improved reservoir heating system |
US20160199559A1 (en) * | 2013-08-23 | 2016-07-14 | Fresenius Medical Care Deutschland Gmbh | Disposable articles for dialysis treatment, dialyzer and a water preparation plant for dialysate |
US9415152B2 (en) | 2007-11-29 | 2016-08-16 | Fresenius Medical Care Holdings, Inc. | Disposable apparatus and kit for conducting dialysis |
US9433720B2 (en) | 2013-03-14 | 2016-09-06 | Fresenius Medical Care Holdings, Inc. | Universal portable artificial kidney for hemodialysis and peritoneal dialysis |
EP2950840A4 (en) * | 2013-02-01 | 2016-09-14 | Medtronic Inc | Modular fluid therapy system having jumpered flow paths and systems and methods for cleaning and disinfection |
US9713665B2 (en) | 2014-12-10 | 2017-07-25 | Medtronic, Inc. | Degassing system for dialysis |
US9717840B2 (en) | 2002-01-04 | 2017-08-01 | Nxstage Medical, Inc. | Method and apparatus for machine error detection by combining multiple sensor inputs |
US9759710B2 (en) | 2008-09-12 | 2017-09-12 | Fresenius Medical Care Holdings, Inc. | Modular reservoir assembly for a hemodialysis and hemofiltration system |
US9872949B2 (en) | 2013-02-01 | 2018-01-23 | Medtronic, Inc. | Systems and methods for multifunctional volumetric fluid control |
US9877865B2 (en) | 2009-03-31 | 2018-01-30 | Abbott Medical Optics Inc. | Cassette capture mechanism |
US9895262B2 (en) | 2012-03-17 | 2018-02-20 | Abbott Medical Optics Inc. | Device, system and method for assessing attitude and alignment of a surgical cassette |
US9895479B2 (en) | 2014-12-10 | 2018-02-20 | Medtronic, Inc. | Water management system for use in dialysis |
US10010663B2 (en) | 2013-02-01 | 2018-07-03 | Medtronic, Inc. | Fluid circuit for delivery of renal replacement therapies |
US10022673B2 (en) | 2007-09-25 | 2018-07-17 | Fresenius Medical Care Holdings, Inc. | Manifolds for use in conducting dialysis |
US20180236155A1 (en) * | 2015-08-11 | 2018-08-23 | Fresenius Medical Care Deutschland Gmbh | Peritoneal dialysis machine |
WO2018187172A1 (en) * | 2017-04-07 | 2018-10-11 | Fresenius Medical Care Holdings, Inc. | Methods and systems for measuring and heating dialysate |
US10098993B2 (en) | 2014-12-10 | 2018-10-16 | Medtronic, Inc. | Sensing and storage system for fluid balance |
US20190015577A1 (en) * | 2017-07-11 | 2019-01-17 | Fresenius Medical Care Holdings, Inc. | Fluid leak detection in a dialysis machine |
US10195326B2 (en) | 2016-03-08 | 2019-02-05 | Fresenius Medical Care Holdings, Inc. | Methods and systems for detecting an occlusion in a blood circuit of a dialysis system |
US10219940B2 (en) | 2008-11-07 | 2019-03-05 | Johnson & Johnson Surgical Vision, Inc. | Automatically pulsing different aspiration levels to an ocular probe |
US10238778B2 (en) | 2008-11-07 | 2019-03-26 | Johnson & Johnson Surgical Vision, Inc. | Automatically switching different aspiration levels and/or pumps to an ocular probe |
US10265443B2 (en) | 2008-11-07 | 2019-04-23 | Johnson & Johnson Surgical Vision, Inc. | Surgical cassette apparatus |
US10342701B2 (en) | 2007-08-13 | 2019-07-09 | Johnson & Johnson Surgical Vision, Inc. | Systems and methods for phacoemulsification with vacuum based pumps |
US10441461B2 (en) | 2006-11-09 | 2019-10-15 | Johnson & Johnson Surgical Vision, Inc. | Critical alignment of fluidics cassettes |
US10533308B2 (en) | 2017-12-18 | 2020-01-14 | George Taweh | Dialysis wall box apparatus and wall chase system |
US10543052B2 (en) | 2013-02-01 | 2020-01-28 | Medtronic, Inc. | Portable dialysis cabinet |
US10561778B2 (en) | 2017-03-02 | 2020-02-18 | Fresenius Medical Care Holdings, Inc. | Split reservoir bags and method of using split reservoir bags to improve the heating and generation of dialysate |
US10695481B2 (en) | 2011-08-02 | 2020-06-30 | Medtronic, Inc. | Hemodialysis system having a flow path with a controlled compliant volume |
US10758662B2 (en) | 2007-11-29 | 2020-09-01 | Fresenius Medical Care Holdings, Inc. | Priming system and method for dialysis systems |
US10758868B2 (en) | 2008-10-30 | 2020-09-01 | Fresenius Medical Care Holdings, Inc. | Methods and systems for leak detection in a dialysis system |
US10786616B2 (en) | 2015-12-17 | 2020-09-29 | Fresnius Medical Care Holdings, Inc. | System and method for controlling venous air recovery in a portable dialysis system |
US10857277B2 (en) | 2011-08-16 | 2020-12-08 | Medtronic, Inc. | Modular hemodialysis system |
US10874787B2 (en) | 2014-12-10 | 2020-12-29 | Medtronic, Inc. | Degassing system for dialysis |
US10905816B2 (en) | 2012-12-10 | 2021-02-02 | Medtronic, Inc. | Sodium management system for hemodialysis |
US10959881B2 (en) | 2006-11-09 | 2021-03-30 | Johnson & Johnson Surgical Vision, Inc. | Fluidics cassette for ocular surgical system |
US10987460B2 (en) | 2016-03-08 | 2021-04-27 | Fresenius Medical Care Holdings, Inc. | Methods and systems of generating rapidly varying pressure amplitudes in fluidic circuits in a dialysis treatment system |
US11033667B2 (en) | 2018-02-02 | 2021-06-15 | Medtronic, Inc. | Sorbent manifold for a dialysis system |
US11110215B2 (en) | 2018-02-23 | 2021-09-07 | Medtronic, Inc. | Degasser and vent manifolds for dialysis |
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US11278654B2 (en) | 2017-12-07 | 2022-03-22 | Medtronic, Inc. | Pneumatic manifold for a dialysis system |
US11337855B2 (en) | 2006-11-09 | 2022-05-24 | Johnson & Johnson Surgical Vision, Inc. | Holding tank devices, systems, and methods for surgical fluidics cassette |
US11525798B2 (en) | 2012-12-21 | 2022-12-13 | Fresenius Medical Care Holdings, Inc. | Method and system of monitoring electrolyte levels and composition using capacitance or induction |
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Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
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US11548161B2 (en) | 2020-05-14 | 2023-01-10 | The Boeing Company | Methods of performing a plurality of operations within a region of a part utilizing an end effector of a robot and robots that perform the methods |
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Citations (92)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3242456A (en) * | 1963-10-07 | 1966-03-22 | Itt | Electrical connector with spring pin contact |
US3709222A (en) * | 1970-12-28 | 1973-01-09 | Sarns Inc | Method and apparatus for automatic peritoneal dialysis |
US3946731A (en) * | 1971-01-20 | 1976-03-30 | Lichtenstein Eric Stefan | Apparatus for extracorporeal treatment of blood |
US4071444A (en) * | 1976-10-12 | 1978-01-31 | Purdue Research Foundation | Portable chemical reactor for use as an artificial kidney |
US4247393A (en) * | 1979-01-11 | 1981-01-27 | Wallace Richard A | Hemodialysis assist device |
US4368737A (en) * | 1980-07-07 | 1983-01-18 | Purdue Research Foundation | Implantable catheter |
US4430098A (en) * | 1976-03-24 | 1984-02-07 | Bowman Donald B | Apparatus for degassing hemodialysis liquid and the like |
US4498902A (en) * | 1982-11-13 | 1985-02-12 | Purdue Research Foundation | Catheter guide |
US4563170A (en) * | 1982-07-30 | 1986-01-07 | Karl Aigner | Device for in vivo purification of blood |
US4806247A (en) * | 1985-04-12 | 1989-02-21 | Baxter International Inc. | Plasmapheresis system and method |
US4897189A (en) * | 1987-10-23 | 1990-01-30 | Research Corporation Limited | Blood purification apparatus |
US4909713A (en) * | 1986-05-07 | 1990-03-20 | Cobe Laboratories, Inc. | Peristaltic pump |
US4990258A (en) * | 1985-06-04 | 1991-02-05 | Gambro Ab | Monitor for the control and/or checking of two or more functions |
US4995268A (en) * | 1989-09-01 | 1991-02-26 | Ash Medical System, Incorporated | Method and apparatus for determining a rate of flow of blood for an extracorporeal blood therapy instrument |
US4997570A (en) * | 1988-11-04 | 1991-03-05 | Fresenius Ag | Method and device for ultrafiltration during hemodialysis |
US5002054A (en) * | 1987-02-25 | 1991-03-26 | Ash Medical Systems, Inc. | Interstitial filtration and collection device and method for long-term monitoring of physiological constituents of the body |
US5100554A (en) * | 1989-11-21 | 1992-03-31 | Fresenius Ag | Method for the in-vivo determination of hemodialysis parameters |
US5198335A (en) * | 1985-06-04 | 1993-03-30 | Fuji Photo Film Co., Ltd. | Integral multilayer analytical element for analysis of ammonia-forming substrate |
US5277820A (en) * | 1992-02-06 | 1994-01-11 | Hemocleanse, Inc. | Device and method for extracorporeal blood treatment |
US5284559A (en) * | 1992-06-16 | 1994-02-08 | Rhode Island Hospital | Preparative electrophoresis device and method |
US5284470A (en) * | 1992-11-02 | 1994-02-08 | Beltz Alex D | Wearable, portable, light-weight artificial kidney |
US5295505A (en) * | 1991-11-28 | 1994-03-22 | Fresenius Ag | Apparatus for preparation of a medicinal solution |
US5385005A (en) * | 1993-07-12 | 1995-01-31 | Ash; Stephen C. | Lawn trimmer/edge attachment |
US5391143A (en) * | 1993-03-12 | 1995-02-21 | Kensey Nash Corporation | Method and system for effecting weight reduction of living beings |
USD355816S (en) * | 1993-11-17 | 1995-02-28 | Ash Stephen C | Trimmer attachment |
US5609770A (en) * | 1995-06-07 | 1997-03-11 | Cobe Laboratories, Inc. | Graphical operator machine interface and method for information entry and selection in a dialysis machine |
US5614677A (en) * | 1994-06-03 | 1997-03-25 | Fresenius Ag | Diaphragm gage for measuring the pressure of a fluid |
US5711883A (en) * | 1995-09-27 | 1998-01-27 | Fresenius Usa, Inc. | Method for testing dialyzer integrity prior to use |
US5713850A (en) * | 1994-12-09 | 1998-02-03 | Fresenius Ag | Apparatus for controlling a fluid flow |
US5725773A (en) * | 1994-11-12 | 1998-03-10 | Fresenius Ag | Method and apparatus for determining the quantity of oremic toxins removed by a hemodialysis treatment |
US5725776A (en) * | 1995-02-13 | 1998-03-10 | Aksys, Ltd. | Methods for ultrafiltration control in hemodialysis |
US5858186A (en) * | 1996-12-20 | 1999-01-12 | The Regents Of The University Of California | Urea biosensor for hemodialysis monitoring |
US5876419A (en) * | 1976-10-02 | 1999-03-02 | Navius Corporation | Stent and method for making a stent |
US6042561A (en) * | 1997-10-22 | 2000-03-28 | Ash Medical Systems, Inc. | Non-intravascular infusion access device |
US6168578B1 (en) * | 1999-02-18 | 2001-01-02 | Melvin Diamond | Portable kidney dialysis system |
US6190349B1 (en) * | 1997-08-06 | 2001-02-20 | Hemocleanse, Inc. | Splittable multiple catheter assembly and methods for inserting the same |
US6196922B1 (en) * | 1994-02-10 | 2001-03-06 | Netzsch Mohnopumpen Gmbh | Universal joint coupling in particular arranged on a universal joint shaft of an eccentric worm machine |
US6196992B1 (en) * | 1995-05-23 | 2001-03-06 | Baxter International Inc. | Portable pump apparatus for continuous ambulatory peritoneal dialysis and a method for providing same |
US6200485B1 (en) * | 1991-10-11 | 2001-03-13 | Chidren's Hospital Medical Center | Hemofiltration system and method |
US6348162B1 (en) * | 1992-09-04 | 2002-02-19 | Viacirq, Inc. | Starting dialysate composition for use as an initial dialysate in hemo dialysis |
US20030012905A1 (en) * | 1998-02-13 | 2003-01-16 | Zumbrum Michael Allen | Flexure endurant composite elastomer compositions |
US6517045B1 (en) * | 1998-10-02 | 2003-02-11 | Ronald Northedge | Valve assembly |
US20030048185A1 (en) * | 2001-09-07 | 2003-03-13 | Citrenbaum, M.D. Richard A. | Apparatus and process for infusion monitoring |
US20030056585A1 (en) * | 1999-12-15 | 2003-03-27 | Shinya Furuki | Thermal flowmeter with fluid descriminant function |
US6607495B1 (en) * | 1999-06-18 | 2003-08-19 | University Of Virginia Patent Foundation | Apparatus for fluid transport and related method thereof |
US6673314B1 (en) * | 1997-02-14 | 2004-01-06 | Nxstage Medical, Inc. | Interactive systems and methods for supporting hemofiltration therapies |
US6685664B2 (en) * | 2001-06-08 | 2004-02-03 | Chf Solutions, Inc. | Method and apparatus for ultrafiltration utilizing a long peripheral access venous cannula for blood withdrawal |
US20040021108A1 (en) * | 2002-07-30 | 2004-02-05 | Siemens-Elema Ab | Valve assembly |
US20040031756A1 (en) * | 2002-07-19 | 2004-02-19 | Terumo Kabushiki Kaisha | Peritoneal dialysis apparatus and control method thereof |
US6695803B1 (en) * | 1998-10-16 | 2004-02-24 | Mission Medical, Inc. | Blood processing system |
US6702561B2 (en) * | 2001-07-12 | 2004-03-09 | Nxstage Medical, Inc. | Devices for potting a filter for blood processing |
US6706007B2 (en) * | 2000-12-29 | 2004-03-16 | Chf Solutions, Inc. | Feedback control of ultrafiltration to prevent hypotension |
US6841172B1 (en) * | 1996-08-14 | 2005-01-11 | Hemocleanse, Inc. | Method for iron delivery to a patient by transfer from dialysate |
US6843779B1 (en) * | 2001-09-17 | 2005-01-18 | Mirimedical, Llc | Hemodialysis system |
US6852090B2 (en) * | 1997-02-14 | 2005-02-08 | Nxstage Medical, Inc. | Fluid processing systems and methods using extracorporeal fluid flow panels oriented within a cartridge |
US20050070837A1 (en) * | 2003-09-25 | 2005-03-31 | Gambro Lundia Ab. | User interface for an extracorporeal blood treatment machine |
US7004924B1 (en) * | 1998-02-11 | 2006-02-28 | Nxstage Medical, Inc. | Methods, systems, and kits for the extracorporeal processing of blood |
US7169303B2 (en) * | 2003-05-28 | 2007-01-30 | Hemocleanse Technologies, Llc | Sorbent reactor for extracorporeal blood treatment systems, peritoneal dialysis systems, and other body fluid treatment systems |
US7174613B2 (en) * | 2003-10-14 | 2007-02-13 | Dreamwell Ltd | Method for manufacturing a foam core having channel cuts |
US7314208B1 (en) * | 2004-09-30 | 2008-01-01 | Sandia Corporation | Apparatus and method for selectively channeling a fluid |
US7317967B2 (en) * | 2001-12-31 | 2008-01-08 | B. Braun Medical Inc. | Apparatus and method for transferring data to a pharmaceutical compounding system |
US20080006570A1 (en) * | 2003-01-23 | 2008-01-10 | National Quality Care, Inc. | Low hydraulic resistance cartridge |
US20080021366A1 (en) * | 2001-11-16 | 2008-01-24 | National Quality Care, Inc | Wearable ultrafiltration device |
US7332096B2 (en) * | 2003-12-19 | 2008-02-19 | Fenwal, Inc. | Blood filter assembly having multiple filtration regions |
US20080041136A1 (en) * | 2006-01-25 | 2008-02-21 | Virbac Corporation | Ammonia detection device and related methods |
US20080041792A1 (en) * | 2006-08-18 | 2008-02-21 | Martin Crnkovich | Wetness sensor |
US20080051689A1 (en) * | 2001-11-16 | 2008-02-28 | National Quality Care, Inc. | Wearable ultrafiltration device |
US20090004053A1 (en) * | 2007-06-29 | 2009-01-01 | Kenley Rodney S | Devices, systems, and methods for cleaning, disinfecting, rinsing, and priming blood separation devices and associated fluid lines |
US20090008306A1 (en) * | 2007-07-05 | 2009-01-08 | Baxter International Inc. | Extracorporeal dialysis ready peritoneal dialysis machine |
US7494590B2 (en) * | 2001-10-02 | 2009-02-24 | Gambro Lundia Ab | Method of controlling a dialysis apparatus |
US7648476B2 (en) * | 2005-03-23 | 2010-01-19 | B. Braun Medizintechnologie Gmbh | Blood treatment apparatus with alarm device |
US20110000830A1 (en) * | 2008-02-07 | 2011-01-06 | Atsushi Ikeda | Hemodialysis apparatus |
US20110000832A1 (en) * | 2003-11-05 | 2011-01-06 | Baxter International Inc. | Dialysis system with enhanced features |
US20110009799A1 (en) * | 2009-05-15 | 2011-01-13 | Interface Biologics, Inc. | Antithrombogenic hollow fiber membranes and filters |
US7873489B2 (en) * | 2005-03-04 | 2011-01-18 | B. Braun Medizintechnologie Gmbh | Dialysis machine with servicing indicator |
US7874999B2 (en) * | 2007-09-24 | 2011-01-25 | Baxter International, Inc. | Detecting access disconnect using needle sleeve |
US20110028882A1 (en) * | 2008-04-04 | 2011-02-03 | Gambro Lundia Ab | medical apparatus |
US20110028881A1 (en) * | 2008-04-04 | 2011-02-03 | Gambro Lundia Ab | Medical apparatus comprising a machine for treatment of fluids |
US7886611B2 (en) * | 2001-04-13 | 2011-02-15 | Chf Solutions Inc. | Pressure sensor disconnect detection for a blood treatment device |
US20110046533A1 (en) * | 2008-04-01 | 2011-02-24 | David Stefani | Apparatus and a method for monitoring a vascular access |
US20110041928A1 (en) * | 2009-08-22 | 2011-02-24 | Voelker Manfred | Supply device for dialysis apparatuses |
US20120010554A1 (en) * | 2010-07-08 | 2012-01-12 | Georges Vantard | Method and apparatus for controlling an extra-corporeal blood treatment in a medical device |
US20120022440A1 (en) * | 2007-07-05 | 2012-01-26 | Baxter Healthcare S.A. | Dialysis system having disposable cassette |
US20120018377A1 (en) * | 2003-12-24 | 2012-01-26 | Chemica Technologies, Inc. | Dialysate regeneration system for portable human dialysis |
US8105260B2 (en) * | 2004-07-23 | 2012-01-31 | Gambro Lundia Ab | Machine and procedure for extracorporeal treatment of blood |
US8105487B2 (en) * | 2007-09-25 | 2012-01-31 | Fresenius Medical Care Holdings, Inc. | Manifolds for use in conducting dialysis |
US20120029937A1 (en) * | 2009-03-24 | 2012-02-02 | Debiotech S.A. | Dialysis device |
US20120029324A1 (en) * | 2010-04-16 | 2012-02-02 | Baxter Healthcare S.A. | Therapy prediction and optimization for renal failure blood therapy, especially home hemodialysis |
US20120031826A1 (en) * | 2007-10-24 | 2012-02-09 | Baxter Healthcare S.A. | Hemodialysis system having clamping mechanism for peristaltic pumping |
US20120035534A1 (en) * | 2008-07-09 | 2012-02-09 | Baxter Healthcare S.A. | Dialysis system including wireless patient data and trending and alert generation |
US8114288B2 (en) * | 2007-11-29 | 2012-02-14 | Fresenlus Medical Care Holdings, Inc. | System and method for conducting hemodialysis and hemofiltration |
US8376978B2 (en) * | 2007-02-09 | 2013-02-19 | Baxter International Inc. | Optical access disconnection systems and methods |
Family Cites Families (512)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2276843A (en) | 1939-03-31 | 1942-03-17 | Gen Electric | Pressure measuring apparatus |
US2328381A (en) | 1940-08-28 | 1943-08-31 | Samuel R Jaffe | Pipe joint |
US2569105A (en) | 1948-02-26 | 1951-09-25 | William J James | Magnetic position responsive device |
US2977791A (en) | 1958-10-03 | 1961-04-04 | Vyzk A Zkusebni Letecky Ustav | Torsional magnetostrictive pressure pick-up |
US3216281A (en) | 1963-07-02 | 1965-11-09 | Gen Motors Corp | Variable speed drive unit |
US3200591A (en) | 1963-09-30 | 1965-08-17 | Itt | Polarized solenoid actuating system |
US3388803A (en) | 1965-04-16 | 1968-06-18 | Applied Biolog Sciences Lab In | Wearable dialysis apparatus |
US3308798A (en) | 1965-05-05 | 1967-03-14 | Kenneth M Snider | Metering valve for crankcase ventilation systems |
US3420492A (en) | 1965-10-06 | 1969-01-07 | Itt | Bistable valve mechanism or the like |
US3464448A (en) | 1965-10-11 | 1969-09-02 | Honeywell Inc | Diaphragm valve |
US3511469A (en) | 1966-05-06 | 1970-05-12 | Eckel Valve Co | Solenoid operated valve |
JPS4413461B1 (en) | 1966-05-18 | 1969-06-17 | ||
US3669878A (en) | 1968-12-02 | 1972-06-13 | Health Education And Welfare U | Treatment of dialysate solution for removal of urea |
US3669880A (en) | 1969-06-30 | 1972-06-13 | Cci Aerospace Corp | Recirculation dialysate system for use with an artificial kidney machine |
US3803913A (en) | 1970-07-06 | 1974-04-16 | J Tracer | Apparatus for determining heat-transfer rates and thus the flow rates or thermal conductivities of fluids |
US3728654A (en) | 1970-09-26 | 1973-04-17 | Hosiden Electronics Co | Solenoid operated plunger device |
DE2239254C2 (en) | 1970-12-30 | 1983-08-04 | Organon Teknika Corp., Oklahoma City, Okla. | "Column for regenerating a circulating dialysate solution and using this column". |
US4370983A (en) | 1971-01-20 | 1983-02-01 | Lichtenstein Eric Stefan | Computer-control medical care system |
BE788759A (en) | 1971-09-14 | 1973-01-02 | Atomic Energy Commission | COMPACT DIALYZER FOR BLOOD DIALYSIS AND OTHER APPLICATIONS |
US3752189A (en) | 1971-09-15 | 1973-08-14 | Moog Inc | Electrical feedback servovalve |
US3850835A (en) | 1971-11-08 | 1974-11-26 | Cci Life Systems Inc | Method of making granular zirconium hydrous oxide ion exchangers, such as zirconium phosphate and hydrous zirconium oxide, particularly for column use |
US3961918A (en) | 1972-03-20 | 1976-06-08 | Johnson Thomas B | Method and apparatus for degassing liquids |
US3894431A (en) | 1972-04-04 | 1975-07-15 | Atomic Energy Authority Uk | Apparatus for indicating fluid flow velocity |
US3814376A (en) | 1972-08-09 | 1974-06-04 | Parker Hannifin Corp | Solenoid operated valve with magnetic latch |
US3918037A (en) | 1972-11-06 | 1975-11-04 | Thomas R Hall | Audio load indicator |
US3994799A (en) | 1973-04-17 | 1976-11-30 | Yao Shang J | Blood and tissue detoxification apparatus |
US3884808A (en) | 1973-06-20 | 1975-05-20 | Res Dev Systems Inc | Wearable, self-regenerating dialysis appliance |
JPS5225197B2 (en) | 1973-09-19 | 1977-07-06 | ||
US4118314A (en) | 1974-01-09 | 1978-10-03 | Seisan Kaihatsu Kagaku Kenkyusho | Apparatus for treatment of artificial kidney dialyzing fluid |
US3902490A (en) | 1974-03-27 | 1975-09-02 | Univ Utah | Portable artificial kidney system |
JPS50126866A (en) | 1974-04-01 | 1975-10-06 | ||
JPS5176991A (en) | 1974-12-27 | 1976-07-03 | Fujitsu Ltd | HANDOTAISOCHINOSEIZOHOHO |
US3989625A (en) | 1975-02-25 | 1976-11-02 | Ma-De Inc. | Detector for air in blood dialysis systems |
US3983361A (en) | 1975-03-20 | 1976-09-28 | Radiant Technology Corporation | Electric heating apparatus for heating corrosive solutions |
US4047099A (en) | 1975-09-15 | 1977-09-06 | Uniloc, Incorporated | Method and apparatus for determining boiler water conductivity |
FR2348447A1 (en) | 1976-04-12 | 1977-11-10 | Damond Cie Auxil Entr Electrom | THERMOSTATIC ENCLOSURE FOR THE PRODUCTION OF A LIQUID AT REQUIRED TEMPERATURE AND DEGREE OF PURITY |
US4079007A (en) | 1976-09-07 | 1978-03-14 | Union Carbide Corporation | Hemodialysis system with modular dialysate manifold assembly |
US4083777A (en) | 1976-09-07 | 1978-04-11 | Union Carbide Corporation | Portable hemodialysis system |
US4155852A (en) | 1976-11-19 | 1979-05-22 | Halbert Fischel | Low leakage current medical instrument |
US4113614A (en) | 1976-12-10 | 1978-09-12 | International Business Machines Corporation | Automated hemodialysis treatment systems |
US4099700A (en) | 1977-02-16 | 1978-07-11 | Wen Young | Flow control device for fluids flowing in a closed conduit |
US4094775A (en) | 1977-02-28 | 1978-06-13 | California Institute Of Technology | Dialysis system |
FR2385406A1 (en) | 1977-03-28 | 1978-10-27 | Akzo Nv | ARTIFICIAL KIDNEY |
US4436620A (en) | 1977-05-09 | 1984-03-13 | Baxter Travenol Laboratories, Inc. | Integral hydraulic circuit for hemodialysis apparatus |
GB1591471A (en) | 1977-06-18 | 1981-06-24 | Hart J C H | Electromagnetic actuators |
US4159748A (en) | 1977-12-12 | 1979-07-03 | Pitney-Bowes, Inc. | Weighing scale |
US4581141A (en) | 1978-02-27 | 1986-04-08 | Purdue Research Foundation | Dialysis material and method for removing uremic substances |
IT1174707B (en) | 1978-05-03 | 1987-07-01 | Bonomini Vittorio | PORTABLE ARTIFICIAL KIDNEY FOR DIALYSIS |
US4209392A (en) | 1978-05-15 | 1980-06-24 | Wallace Richard A | Portable hepatic-assist method and apparatus for same |
DE2838414C2 (en) | 1978-09-02 | 1984-10-31 | Fresenius AG, 6380 Bad Homburg | Device for hemodialysis and for withdrawing ultrafiltrate |
US4259985A (en) | 1978-12-18 | 1981-04-07 | Brunswick Corporation | Three-way solenoid-operated pinch valve assembly |
JPS5814223B2 (en) | 1979-02-24 | 1983-03-17 | 株式会社メデクス | Dialysis “filtration” device |
US4535637A (en) | 1979-04-19 | 1985-08-20 | Wilgood Corporation | Flow detection apparatus |
US4326955A (en) | 1979-06-14 | 1982-04-27 | Diachem, Inc. | Hemodialysis with sodium bicarbonate dialysate prepared in plural stages |
WO1980002806A1 (en) | 1979-06-20 | 1980-12-24 | Newhart R | Blood perfusion units |
US4390073A (en) | 1979-10-02 | 1983-06-28 | Engineering & Research Associates, Inc. | Blood collection bag weighing device |
US4403765A (en) | 1979-11-23 | 1983-09-13 | John F. Taplin | Magnetic flux-shifting fluid valve |
US4403984A (en) | 1979-12-28 | 1983-09-13 | Biotek, Inc. | System for demand-based adminstration of insulin |
JPS5928698Y2 (en) | 1980-03-22 | 1984-08-18 | 株式会社丸山製作所 | Support device for mounted spreaders |
JPH0219845Y2 (en) | 1980-09-17 | 1990-05-31 | ||
US4348283A (en) | 1980-11-05 | 1982-09-07 | Purdue Research Foundation | Reciprocating dialyzer having spacers |
US4354562A (en) | 1980-12-03 | 1982-10-19 | Newman Martin H | Electronic weighing device |
US4397189A (en) | 1981-04-28 | 1983-08-09 | Cobe Laboratories, Inc. | Measuring low flowrates |
US4371385A (en) | 1981-04-28 | 1983-02-01 | Cobe Laboratories, Inc. | Deaerating liquid |
US4381999A (en) | 1981-04-28 | 1983-05-03 | Cobe Laboratories, Inc. | Automatic ultrafiltration control system |
US4731072A (en) | 1981-05-11 | 1988-03-15 | Mcneilab, Inc. | Apparatus for heating or cooling fluids |
US4397519A (en) * | 1981-05-12 | 1983-08-09 | Pylon Company, Inc. | Electrical contact construction |
US4402694A (en) | 1981-07-16 | 1983-09-06 | Biotek, Inc. | Body cavity access device containing a hormone source |
US4443333A (en) | 1981-09-24 | 1984-04-17 | Mahurkar Sakharam D | Portable dialysis system and pump therefor |
US4466804A (en) | 1981-09-25 | 1984-08-21 | Tsunekazu Hino | Extracorporeal circulation of blood |
US4387777A (en) | 1981-10-26 | 1983-06-14 | Willo Partners | Calorie counting method and apparatus |
US4531799A (en) * | 1982-01-04 | 1985-07-30 | Raytheon Company | Electrical connector |
DE3374660D1 (en) | 1982-03-10 | 1988-01-07 | Toyoda Chuo Kenkyusho Kk | Blood purification apparatus |
US4413988A (en) | 1982-04-28 | 1983-11-08 | Handt Alan E | Short-tubing set gravity powered peritoneal cycler |
JPS5913770U (en) | 1982-07-19 | 1984-01-27 | 吉川 敬一郎 | Valve opening/closing monitoring device using light |
US4477342A (en) | 1982-08-31 | 1984-10-16 | Becton, Dickinson And Company | Apparatus and method for controlling ultrafiltration during hemodialysis |
US4650587A (en) | 1982-09-09 | 1987-03-17 | Akzona Incorporated | Ammonia scavenger |
US4460555A (en) | 1983-08-25 | 1984-07-17 | Organon Teknika Corporation | Ammonia scavenger |
US4596550A (en) | 1982-09-24 | 1986-06-24 | Baxter Travenol Laboratories, Inc. | Method and apparatus for ultrafiltration measurement in a two pump dialysis system |
US4586576A (en) | 1982-09-28 | 1986-05-06 | Inoue-Japax Research Incorporated | Measuring system |
JPS59127978U (en) | 1983-02-18 | 1984-08-28 | エヌオーケー株式会社 | proportional control solenoid valve |
ATE22013T1 (en) | 1983-03-01 | 1986-09-15 | Sartorius Gmbh | DEVICE FOR PREPARATION OF MEDICAL INFUSION SOLUTIONS. |
US4480483A (en) | 1983-04-06 | 1984-11-06 | Westinghouse Electric Corp. | Acousto-optical ultrasonic flowmeter |
JPS6037674U (en) | 1983-08-22 | 1985-03-15 | シ−ケ−ディコントロ−ルズ株式会社 | gas shutoff valve |
US4680122A (en) | 1983-09-10 | 1987-07-14 | Organon Teknika Corporation | Ultrafiltration control for hemodialysis |
US4630799A (en) | 1983-09-14 | 1986-12-23 | Nolan John H | Remotely controlled override valve with calibration means |
US4559039A (en) | 1983-12-05 | 1985-12-17 | Purdue Research Foundation | Permanently placed transcutaneous access device to blood vessels |
JPS60108870U (en) | 1983-12-28 | 1985-07-24 | エヌオーケー株式会社 | gas shutoff valve |
US4765907A (en) | 1984-03-28 | 1988-08-23 | Research Development Systems, Inc. | Wearable, continuously internally operable and externally regenerable dialysis device |
US4710164A (en) | 1984-05-01 | 1987-12-01 | Henry Ford Hospital | Automated hemodialysis control based upon patient blood pressure and heart rate |
DE3416955C2 (en) | 1984-05-08 | 1986-06-12 | Fresenius AG, 6380 Bad Homburg | Hemodialysis machine |
US4661246A (en) | 1984-10-01 | 1987-04-28 | Ash Medical Systems, Inc. | Dialysis instrument with dialysate side pump for moving body fluids |
JPS61119276A (en) | 1984-11-14 | 1986-06-06 | 株式会社 ニツシヨ− | Apparatus and method for controlling ultrafiltration amount |
DE3508151A1 (en) | 1985-03-07 | 1986-09-11 | M A N Technologie GmbH, 8000 München | MAGNETIC QUICK-RELEASE VALVE |
US4840542A (en) | 1985-03-27 | 1989-06-20 | Quest Medical, Inc. | Infusion pump with direct pressure sensing |
IT1191613B (en) | 1985-05-15 | 1988-03-23 | Eniricerche Spa | ZIRCONIUM PHOSPHATE AND ITS PREPARATION METHOD |
SE447963B (en) | 1985-06-04 | 1987-01-12 | Gambro Ab | DIALYSIS CONTROL SYSTEM |
US4666598A (en) | 1985-06-25 | 1987-05-19 | Cobe Laboratories, Inc. | Apparatus for use with fluid flow transfer device |
US4599055A (en) | 1985-06-25 | 1986-07-08 | Cobe Laboratories, Inc. | Peristaltic pump |
US4828543A (en) | 1986-04-03 | 1989-05-09 | Weiss Paul I | Extracorporeal circulation apparatus |
US4740755A (en) | 1986-05-30 | 1988-04-26 | Cobe Laboratories, Inc. | Remote conductivity sensor having transformer coupling in fluid flow path |
US5074368A (en) | 1986-06-13 | 1991-12-24 | K-Tron Technologies, Inc. | Self-calibrating apparatus for article input and removal monitoring system |
US4968422A (en) | 1986-06-23 | 1990-11-06 | Runge Thomas M | Pulsatile flow hemodialysis |
EP0259668B1 (en) | 1986-09-01 | 1990-12-12 | Siemens Aktiengesellschaft | Piston pump for a dosed medicament delivery device |
ES2046981T3 (en) | 1986-09-30 | 1994-02-16 | Siemens Ag | ULTRASONIC METER OF CIRCULATION SPEED ACCORDING TO THE PRINCIPLE OF PHASE DIFFERENCE. |
NL8602690A (en) | 1986-10-27 | 1988-05-16 | Servex Bv | DEVICE FOR DETERMINING THE FLOW RATE OF A MEDIUM IN A CYLINDRICAL PIPE. |
DE3636995A1 (en) | 1986-10-30 | 1988-05-11 | Fresenius Ag | METHOD AND DEVICE FOR EXTRACTING HEAT FROM BLOOD IN THE EXTRACORPORAL CIRCUIT |
FR2607393B1 (en) | 1986-11-28 | 1997-01-24 | Hospal Ind | ARTIFICIAL KIDNEY AT MODERATE EXCHANGE RATES |
JP2586470B2 (en) | 1987-02-17 | 1997-02-26 | 松下電器産業株式会社 | Heated object for induction heating cooker |
US4854322A (en) | 1987-02-25 | 1989-08-08 | Ash Medical Systems, Inc. | Capillary filtration and collection device for long-term monitoring of blood constituents |
US4777953A (en) | 1987-02-25 | 1988-10-18 | Ash Medical Systems, Inc. | Capillary filtration and collection method for long-term monitoring of blood constituents |
US4950244A (en) | 1987-05-01 | 1990-08-21 | Abbott Laboratories | Pressure sensor assembly for disposable pump cassette |
JPS63192912U (en) | 1987-05-30 | 1988-12-13 | ||
US4765421A (en) | 1987-06-11 | 1988-08-23 | Newton Robert F | Folding scale |
US5170789A (en) | 1987-06-17 | 1992-12-15 | Perinchery Narayan | Insertable NMR coil probe |
US4861242A (en) | 1987-08-19 | 1989-08-29 | Cobe Laboratories, Inc. | Self-loading peristaltic pump |
US4882937A (en) | 1987-08-20 | 1989-11-28 | Liberty Technology Center, Inc. | Strain sensor for attachment to a structural member |
US4828693A (en) | 1987-09-22 | 1989-05-09 | Baxter Travenol Laboratories, Inc. | Water pressure regulator for hemodialysis apparatus |
DE3875075D1 (en) | 1987-11-25 | 1992-11-05 | Siemens Ag | DOSING DEVICE FOR CONTROLLED INJECTION OF LIQUIDS FROM A STORAGE CONTAINER INTO AN ORGANISM. |
US4815547A (en) | 1987-11-30 | 1989-03-28 | Toledo Scale Corporation | Load cell |
US5009101A (en) | 1988-01-19 | 1991-04-23 | Westinghouse Electric Corporation | Method and apparatus for monitoring and measuring dynamic loads in thrust inducing systems |
US4802540A (en) | 1988-01-29 | 1989-02-07 | Consolidated Devices Inc. | Electronic weighing scales |
JPH03502410A (en) | 1988-02-03 | 1991-06-06 | シュティーラー エレクトロニック メディツィンテクニーシュ ゲレーテ プロドゥクツィオン‐ウント フェルトリープス‐ゲー・エム・ベー・ハー | Heating device for operating table |
DE3816128C1 (en) | 1988-05-11 | 1989-09-28 | Mc Medizingeraete Gmbh, 8755 Alzenau, De | |
US5032261A (en) | 1988-05-24 | 1991-07-16 | Dufresne-Henry, Inc. | Compact biofilter for drinking water treatment |
US4823597A (en) | 1988-06-06 | 1989-04-25 | Myrick-White, Inc. | Sliver measuring apparatus |
US4881839A (en) | 1988-06-14 | 1989-11-21 | Texas Instruments Incorporated | Portable electronic data handling/data entry system |
US5230341A (en) | 1988-08-13 | 1993-07-27 | Fresenius Ag | Measuring the change of intravascular blood volume during blood filtration |
US4943279A (en) | 1988-09-30 | 1990-07-24 | C. R. Bard, Inc. | Medical pump with infusion controlled by a detachable coded label |
US4931777A (en) | 1988-11-16 | 1990-06-05 | Chiang Cheng San | Low level alarm for drop-feed injection liquid |
US5000274A (en) | 1989-01-19 | 1991-03-19 | K-Tron International, Inc. | Weight sensor |
JPH02114269U (en) | 1989-03-01 | 1990-09-12 | ||
DE3914031C2 (en) | 1989-04-28 | 1993-10-28 | Deutsche Aerospace | Micromechanical actuator |
US4914819A (en) | 1989-05-17 | 1990-04-10 | Ash Stephen R | Eating utensil for indicating when food may be eaten therewith and a method for using the utensil |
DE3917251A1 (en) | 1989-05-26 | 1990-11-29 | Fresenius Ag | Sodium biscarboxylate-containing concentrate and method for producing a dihydrogenation liquid |
US5114580A (en) | 1989-06-20 | 1992-05-19 | The Board Of Regents Of The University Of Washington | Combined hemofiltration and hemodialysis system |
US5215450A (en) | 1991-03-14 | 1993-06-01 | Yehuda Tamari | Innovative pumping system for peristaltic pumps |
US5188604A (en) | 1989-09-29 | 1993-02-23 | Rocky Mountain Research, Inc. | Extra corporeal support system |
US5157332A (en) | 1989-10-13 | 1992-10-20 | The Foxboro Company | Three-toroid electrodeless conductivity cell |
DE3936785C1 (en) | 1989-11-04 | 1991-03-28 | Fresenius Ag, 6380 Bad Homburg, De | |
US5405320A (en) | 1990-01-08 | 1995-04-11 | The Curators Of The University Of Missouri | Multiple lumen catheter for hemodialysis |
US5347115A (en) | 1990-01-12 | 1994-09-13 | Norand Corporation | Portable modular work station including printer and portable data collection terminal |
JP2524876Y2 (en) | 1990-05-28 | 1997-02-05 | 株式会社三陽電機製作所 | Hemodialysis machine |
US5258127A (en) | 1990-07-27 | 1993-11-02 | Pall Corporation | Leucocyte depleting filter device and method of use |
DE4024054A1 (en) | 1990-07-28 | 1992-01-30 | Bosch Gmbh Robert | MAGNETIC SYSTEM |
CA2092201A1 (en) | 1990-08-20 | 1992-02-21 | Joaquin Mayoral | Medical drug formulation and delivery system |
US5152174A (en) | 1990-09-24 | 1992-10-06 | Labudde Edward V | Mass flow rate sensor and method |
US5228308A (en) | 1990-11-09 | 1993-07-20 | General Electric Company | Refrigeration system and refrigerant flow control apparatus therefor |
US5486286A (en) | 1991-04-19 | 1996-01-23 | Althin Medical, Inc. | Apparatus for performing a self-test of kidney dialysis membrane |
US5220843A (en) | 1991-07-26 | 1993-06-22 | Portland General Electric Corporation | In situ method of determining the thrust on valve components |
US5360445A (en) | 1991-11-06 | 1994-11-01 | International Business Machines Corporation | Blood pump actuator |
DE4138140C2 (en) | 1991-11-20 | 1993-12-23 | Fresenius Ag | Device for disinfecting hemodialysis machines with a powdered concentrate |
JPH05172268A (en) | 1991-12-26 | 1993-07-09 | Hitachi Metals Ltd | Valve for gas rate-of-flow control device |
JP2800863B2 (en) * | 1991-12-27 | 1998-09-21 | 澁谷工業株式会社 | Portable dialysis machine |
US5919369A (en) | 1992-02-06 | 1999-07-06 | Hemocleanse, Inc. | Hemofiltration and plasmafiltration devices and methods |
US5536412A (en) | 1992-02-06 | 1996-07-16 | Hemocleanse, Inc. | Hemofiltration and plasmafiltration devices and methods |
US5339699A (en) | 1992-03-02 | 1994-08-23 | Advanced Mechanical Technology, Inc. | Displacement/force transducers utilizing hall effect sensors |
JP3240390B2 (en) | 1992-03-04 | 2001-12-17 | オムロン株式会社 | Displacement detection sensor |
DE4208274C1 (en) | 1992-03-13 | 1993-10-21 | Medical Support Gmbh | Method and arrangement for rinsing and filling the extracorporeal blood circuit of dialysis machines |
US5230614A (en) | 1992-06-03 | 1993-07-27 | Allergan, Inc. | Reduced pulsation tapered ramp pump head |
NO306806B1 (en) | 1992-06-26 | 1999-12-27 | Fresenius Ag | Bag for absorption of concentrate |
US5476444A (en) | 1992-09-04 | 1995-12-19 | Idt, Inc. | Specialized perfusion protocol for whole-body hyperthermia |
DE4230513C1 (en) | 1992-09-11 | 1994-03-31 | Fresenius Ag | Device for removing aluminum ions from blood and solution for use in the device |
US5408576A (en) | 1992-10-28 | 1995-04-18 | Bishop; Robert A. | IV fluid warmer |
DE4239937C2 (en) | 1992-11-27 | 1995-08-24 | Fresenius Ag | Method for determining the functionality of a partial device of a hemodialysis machine and device for carrying out this method |
US5910252A (en) | 1993-02-12 | 1999-06-08 | Cobe Laboratories, Inc. | Technique for extracorporeal treatment of blood |
US5441636A (en) | 1993-02-12 | 1995-08-15 | Cobe Laboratories, Inc. | Integrated blood treatment fluid module |
US5322519A (en) | 1993-02-17 | 1994-06-21 | Ash Medical Systems, Inc. | Foldable catheter for peritoneal dialysis |
ATE170759T1 (en) | 1993-03-03 | 1998-09-15 | Deka Products Lp | DEVICE FOR PERITONAL DIALYSIS WITH A LIQUID DISTRIBUTION AND PUMP CASSETTE EQUIPPED FOR AIR SEPARATION. |
US5624551A (en) | 1993-04-28 | 1997-04-29 | Fresenius Ag | Hydraulic safety circuit for a hemodialysis apparatus |
US5400661A (en) | 1993-05-20 | 1995-03-28 | Advanced Mechanical Technology, Inc. | Multi-axis force platform |
US5346472A (en) | 1993-06-02 | 1994-09-13 | Baxter International Inc. | Apparatus and method for preventing hypotension in a dialysis patient |
DE4321927C2 (en) | 1993-07-01 | 1998-07-09 | Sartorius Gmbh | Filter unit with degassing device |
US5308315A (en) | 1993-07-27 | 1994-05-03 | Raja N. Khuri | Method for determining the adequacy of dialysis |
US5445630A (en) | 1993-07-28 | 1995-08-29 | Richmond; Frank M. | Spike with luer fitting |
USD370531S (en) | 1993-10-04 | 1996-06-04 | Janin Group, Inc. | Peritoneal dialysis catheter implanter |
US5460493A (en) | 1993-11-17 | 1995-10-24 | Baxter International Inc. | Organizer frame for holding an array of flexible tubing in alignment with one or more peristaltic pump rotors |
US5577891A (en) | 1993-11-30 | 1996-11-26 | Instech Laboratories, Inc. | Low power portable resuscitation pump |
US5415532A (en) | 1993-11-30 | 1995-05-16 | The United States Of America As Represented By The Secretary Of The Army | High effieciency balanced oscillating shuttle pump |
US5469737A (en) | 1993-12-20 | 1995-11-28 | Westinghouse Electric Corporation | Method and apparatus for measuring the axial load and position of a valve stem |
CN2183771Y (en) * | 1994-04-07 | 1994-11-30 | 上海师范大学 | Ozone disinfection apparatus for oral surgery instruments |
FI94909C (en) | 1994-04-19 | 1995-11-10 | Valtion Teknillinen | Acoustic flow measurement method and applicable device |
US5545131A (en) | 1994-04-28 | 1996-08-13 | White Eagle International Technologies, Lp | Artificial kidney |
DE4422100C1 (en) | 1994-06-24 | 1995-12-14 | Fresenius Ag | Flexible medical packaging unit for haemodialysis |
US5695473A (en) | 1994-07-27 | 1997-12-09 | Sims Deltec, Inc. | Occlusion detection system for an infusion pump |
US5518015A (en) | 1994-09-30 | 1996-05-21 | Gas Research Institute | Automatic calibrating electrically controlled diaphragm valve actuators and methods for their calibration |
EP0715008B1 (en) | 1994-11-29 | 1997-10-22 | M & M ELECTRIC SERVICE CO. INC. | Solid-state sliver sensor |
US5644285A (en) | 1995-02-01 | 1997-07-01 | Honeywell Inc. | Pressure transducer with media isolation |
US5782796A (en) * | 1995-02-10 | 1998-07-21 | Baxter International Inc. | Foldable dialysis unit with integral pump and a method for performing solution exchange |
US5647853A (en) | 1995-03-03 | 1997-07-15 | Minimed Inc. | Rapid response occlusion detector for a medication infusion pump |
US5629871A (en) | 1995-06-07 | 1997-05-13 | Cobe Laboratories, Inc. | Wear trend analysis technique for components of a dialysis machine |
US5795317A (en) | 1995-06-07 | 1998-08-18 | Cobe Laboratories, Inc. | Extracorporeal blood processing methods and apparatus |
US5693008A (en) | 1995-06-07 | 1997-12-02 | Cobe Laboratories, Inc. | Dialysis blood tubing set |
US5624572A (en) | 1995-06-07 | 1997-04-29 | Cobe Laboratories, Inc. | Power management system and method for maximizing heat delivered to dialysate in a dialysis machine |
US5650704A (en) | 1995-06-29 | 1997-07-22 | Massachusetts Institute Of Technology | Elastic actuator for precise force control |
IT1276468B1 (en) | 1995-07-04 | 1997-10-31 | Hospal Dasco Spa | AUTOMATIC DIALYSIS METHOD AND EQUIPMENT |
US5698083A (en) | 1995-08-18 | 1997-12-16 | Regents Of The University Of California | Chemiresistor urea sensor |
US5944684A (en) | 1995-08-31 | 1999-08-31 | The Regents Of The University Of California | Wearable peritoneum-based system for continuous renal function replacement and other biomedical applications |
US5938634A (en) * | 1995-09-08 | 1999-08-17 | Baxter International Inc. | Peritoneal dialysis system with variable pressure drive |
US5928177A (en) | 1995-09-15 | 1999-07-27 | Cobe Laboratories, Inc. | Technique for loading a pump header within a peristaltic pump of a dialysis machine |
US5765591A (en) | 1995-11-20 | 1998-06-16 | Argonaut Technologies, Inc. | Valve apparatus and method for distributing fluids |
US6836201B1 (en) | 1995-12-01 | 2004-12-28 | Raytheon Company | Electrically driven bistable mechanical actuator |
WO1997027490A1 (en) | 1996-01-25 | 1997-07-31 | General Dynamics Information Systems, Inc. | Performing an operation on an integrated circuit |
US5840068A (en) | 1996-02-28 | 1998-11-24 | Cartledge; Richard G. | Rapid infusion system |
SE509424C2 (en) | 1996-04-12 | 1999-01-25 | Gambro Med Tech Ab | Gases elimination system from a container containing bicarbonate powder and water |
DE19620591B4 (en) | 1996-05-22 | 2004-08-26 | Fresenius Medical Care Deutschland Gmbh | Device for removing gases from liquids |
US6047108A (en) | 1996-10-01 | 2000-04-04 | Baxter International Inc. | Blood warming apparatus |
US5902336A (en) | 1996-10-15 | 1999-05-11 | Mirimedical, Inc. | Implantable device and method for removing fluids from the blood of a patient method for implanting such a device and method for treating a patient experiencing renal failure |
US6409699B1 (en) | 1996-10-22 | 2002-06-25 | Renal Solutions, Inc. | Continuous flow-through peritoneal dialysis (CFPD) method with control of intraperitoneal pressure |
BR9713286A (en) | 1996-11-22 | 1999-10-26 | Therakos Inc | Integrated fluid control cartridge with an integral filter |
AU5447498A (en) | 1996-11-26 | 1998-06-22 | Medisystems Technology Corporation | Wide bubble traps |
US6354565B1 (en) | 1997-02-04 | 2002-03-12 | Phillip George Doust | Washer assembly for a faucet |
US6062256A (en) | 1997-02-11 | 2000-05-16 | Engineering Measurements Company | Micro mass flow control apparatus and method |
US6638478B1 (en) | 1997-02-14 | 2003-10-28 | Nxstage Medical, Inc. | Synchronized volumetric fluid balancing systems and methods |
US20010016699A1 (en) | 1997-02-14 | 2001-08-23 | Jeffrey H. Burbank | Hemofiltration system |
US6638477B1 (en) | 1997-02-14 | 2003-10-28 | Nxstage Medical, Inc. | Fluid replacement systems and methods for use in hemofiltration |
US6554789B1 (en) | 1997-02-14 | 2003-04-29 | Nxstage Medical, Inc. | Layered fluid circuit assemblies and methods for making them |
US6830553B1 (en) | 1997-02-14 | 2004-12-14 | Nxstage Medical, Inc. | Blood treatment systems and methods that maintain sterile extracorporeal processing conditions |
US6979309B2 (en) | 1997-02-14 | 2005-12-27 | Nxstage Medical Inc. | Systems and methods for performing blood processing and/or fluid exchange procedures |
US6579253B1 (en) | 1997-02-14 | 2003-06-17 | Nxstage Medical, Inc. | Fluid processing systems and methods using extracorporeal fluid flow panels oriented within a cartridge |
US6595943B1 (en) | 1997-02-14 | 2003-07-22 | Nxstage Medical, Inc. | Systems and methods for controlling blood flow and waste fluid removal during hemofiltration |
US5760313A (en) | 1997-03-05 | 1998-06-02 | Honeywell Inc. | Force sensor with multiple piece actuation system |
US5980481A (en) | 1997-05-08 | 1999-11-09 | Transvivo, Inc. | Method and apparatus for continuous peritoneal cascade dialysis and hemofiltration (CPCD/H) |
US6117100A (en) | 1997-06-06 | 2000-09-12 | Powers; Kathleen M. | Hemodialysis-double dialyzers in parallel |
US6069343A (en) | 1997-07-17 | 2000-05-30 | Kolowich; J. Bruce | Peritoneal dialysis solution warmer |
US6228047B1 (en) | 1997-07-28 | 2001-05-08 | 1274515 Ontario Inc. | Method and apparatus for performing peritoneal dialysis |
GB2327763B (en) | 1997-08-01 | 1999-06-23 | Rotork Controls | Improved thrust sensors |
US5945343A (en) | 1997-08-05 | 1999-08-31 | Bayer Corporation | Fluorescent polymeric sensor for the detection of urea |
FR2767477B1 (en) | 1997-08-21 | 1999-10-08 | Hospal Ind | DIALYSIS APPARATUS FOR INDEPENDENTLY CONTROLLING THE CONCENTRATION OF AT LEAST TWO IONIC SUBSTANCES IN THE INTERIOR OF A PATIENT |
US6280406B1 (en) | 1997-09-12 | 2001-08-28 | Gambro, Inc | Extracorporeal blood processing system |
US6121555A (en) | 1997-10-10 | 2000-09-19 | Northgate Technologies Incorporated | Fluid container sensor |
US5951870A (en) | 1997-10-21 | 1999-09-14 | Dsu Medical Corporation | Automatic priming of blood sets |
JP3872190B2 (en) * | 1997-11-12 | 2007-01-24 | テルモ株式会社 | Medical equipment |
US5989438A (en) | 1997-12-12 | 1999-11-23 | Baxter International Inc. | Active blood filter and method for active blood filtration |
US6012342A (en) | 1997-12-29 | 2000-01-11 | Cobe Cardiovascular Operating Co., Inc. | Plunger assembly for measuring occlusion pressure on a flexible tube |
WO1999037335A1 (en) | 1998-01-23 | 1999-07-29 | Hemotherm, Inc. | Apparatuses and processes for whole-body hyperthermia |
US6582385B2 (en) | 1998-02-19 | 2003-06-24 | Nstage Medical, Inc. | Hemofiltration system including ultrafiltrate purification and re-infusion system |
US7647237B2 (en) * | 1998-04-29 | 2010-01-12 | Minimed, Inc. | Communication station and software for interfacing with an infusion pump, analyte monitor, analyte meter, or the like |
US6240789B1 (en) | 1998-05-15 | 2001-06-05 | Crane Nuclear, Inc. | Permanently instrumented actuated valve assembly, with internally-gauged, permanently instrumented shaft |
DE19823836C2 (en) | 1998-05-28 | 2000-05-04 | Fresenius Medical Care De Gmbh | Device and method for non-contact measurement of the conductivity of a liquid in a flow channel |
US6491673B1 (en) | 1998-06-26 | 2002-12-10 | The Procter & Gamble Company | Disposable urine collector |
US6116269A (en) | 1998-07-07 | 2000-09-12 | Fasco Controls Corporation | Solenoid pressure transducer |
US6287516B1 (en) | 1998-07-10 | 2001-09-11 | Immunocept, L.L.C. | Hemofiltration systems, methods, and devices used to treat inflammatory mediator related disease |
US6217540B1 (en) | 1998-07-10 | 2001-04-17 | Fuji Photo Film Co., Ltd. | Blood filter cartridge |
JP4334771B2 (en) | 1998-07-31 | 2009-09-30 | ネフロス・インコーポレーテッド | Efficient hemodiafiltration |
US6958049B1 (en) | 1998-08-25 | 2005-10-25 | Ash Access Technology, Inc. | Method of enhancing catheter patency using a citrate salt catheter lock solution |
US6044691A (en) | 1998-08-26 | 2000-04-04 | Aksys, Ltd. | Blood tubing set integrity tests for extracorporeal circuits |
CN1235849A (en) | 1998-09-17 | 1999-11-24 | 彭罗民 | Automatic hemodialysis filter |
US6468427B1 (en) | 1998-09-29 | 2002-10-22 | Gambro, Inc. | Fluid filter for use in extracorporeal blood processing |
JP2000107283A (en) | 1998-10-07 | 2000-04-18 | Nissho Corp | Dialysis apparatus and washing priming method |
US7766873B2 (en) | 1998-10-29 | 2010-08-03 | Medtronic Minimed, Inc. | Method and apparatus for detecting occlusions in an ambulatory infusion pump |
US6414252B1 (en) | 1998-11-16 | 2002-07-02 | Mettler-Toledo Gmbh | Calibration system for a weighing scale |
WO2000032105A1 (en) | 1998-11-25 | 2000-06-08 | Ball Semiconductor, Inc. | Monitor for interventional procedures |
US6254567B1 (en) | 1999-02-26 | 2001-07-03 | Nxstage Medical, Inc. | Flow-through peritoneal dialysis systems and methods with on-line dialysis solution regeneration |
US6332985B1 (en) | 1999-03-29 | 2001-12-25 | Uop Llc | Process for removing toxins from bodily fluids using zirconium or titanium microporous compositions |
WO2000064510A1 (en) | 1999-04-23 | 2000-11-02 | Nephros Therapeutics, Inc. | Extracorporeal circuit and related methods |
US6416293B1 (en) | 1999-07-20 | 2002-07-09 | Deka Products Limited Partnership | Pumping cartridge including a bypass valve and method for directing flow in a pumping cartridge |
US6406631B1 (en) | 1999-07-30 | 2002-06-18 | Nephros, Inc. | Two stage diafiltration method and apparatus |
US7780619B2 (en) | 1999-11-29 | 2010-08-24 | Nxstage Medical, Inc. | Blood treatment apparatus |
ATE366591T1 (en) | 1999-12-22 | 2007-08-15 | Gambro Inc | DEVICE FOR EXTRACORPOREAL BLOOD TREATMENT |
WO2001047580A1 (en) | 1999-12-23 | 2001-07-05 | Membrana Gmbh | Haemofiltration system |
US6716356B2 (en) | 2000-01-11 | 2004-04-06 | Nephros, Inc. | Thermally enhanced dialysis/diafiltration system |
US6328699B1 (en) | 2000-01-11 | 2001-12-11 | Cedars-Sinai Medical Center | Permanently implantable system and method for detecting, diagnosing and treating congestive heart failure |
US6609698B1 (en) | 2000-10-25 | 2003-08-26 | Arichell Technologies, Inc. | Ferromagnetic/fluid valve actuator |
US6948697B2 (en) | 2000-02-29 | 2005-09-27 | Arichell Technologies, Inc. | Apparatus and method for controlling fluid flow |
DE60114999T2 (en) | 2000-03-14 | 2006-09-07 | Speed-Trap.Com Ltd., Newbury | MONITORING AND INTERACTION WITH NETWORK SERVICES |
US6497675B1 (en) | 2000-04-17 | 2002-12-24 | Renal Tech International Llc | Device for extracorporeal treatment of physiological fluids of organism |
JP2001317646A (en) | 2000-05-08 | 2001-11-16 | Smc Corp | Piezoelectric fluid control valve |
US6890315B1 (en) | 2000-05-23 | 2005-05-10 | Chf Solutions, Inc. | Method and apparatus for vein fluid removal in heart failure |
TW441734U (en) | 2000-07-27 | 2001-06-16 | Ind Tech Res Inst | Switch mechanism of gas control module |
DE10042324C1 (en) | 2000-08-29 | 2002-02-07 | Fresenius Medical Care De Gmbh | Blood dialysis device has feed line provided with 2 parallel branches for single needle and dual needle operating modes |
CN100363066C (en) | 2000-10-12 | 2008-01-23 | 肾脏治疗公司 | Device and method for body fluid flow control in extracorpereal fluid treatment |
JP4004009B2 (en) | 2000-10-16 | 2007-11-07 | 富士フイルム株式会社 | Integrated multilayer analytical element for analysis of ammonia or ammonia-producing substances |
DE10053441B4 (en) | 2000-10-27 | 2004-04-15 | Fresenius Medical Care Deutschland Gmbh | Disposable cassette with sealing membrane and valve actuator therefor |
JP2002139165A (en) | 2000-11-02 | 2002-05-17 | Matsushita Electric Ind Co Ltd | Motor-driven valve |
US6487904B1 (en) | 2000-11-09 | 2002-12-03 | Rosemont Aerospace Inc. | Method and sensor for mass flow measurement using probe heat conduction |
US6689083B1 (en) | 2000-11-27 | 2004-02-10 | Chf Solutions, Inc. | Controller for ultrafiltration blood circuit which prevents hypotension by monitoring osmotic pressure in blood |
US6627164B1 (en) | 2000-11-28 | 2003-09-30 | Renal Solutions, Inc. | Sodium zirconium carbonate and zirconium basic carbonate and methods of making the same |
US7033498B2 (en) | 2000-11-28 | 2006-04-25 | Renal Solutions, Inc. | Cartridges useful in cleaning dialysis solutions |
US6659973B2 (en) | 2001-01-04 | 2003-12-09 | Transvivo, Inc. | Apparatus and method for in-vivo plasmapheresis using periodic backflush |
US6610036B2 (en) | 2001-02-06 | 2003-08-26 | Vista Innovations, Inc. | Eye drop dispensing system |
US20110098624A1 (en) | 2001-02-14 | 2011-04-28 | Mccotter Craig | Method and apparatus for treating renal disease with hemodialysis utilizing pulsatile pump |
EP1399193B1 (en) | 2001-02-16 | 2014-01-08 | Piedmont Renal Clinics, P.A. | Automated peritoneal dialysis system and process with in-line sterilization of dialysate |
CN1372978A (en) | 2001-02-19 | 2002-10-09 | 尼普洛株式会社 | Dialysis system and its operation method |
US6632192B2 (en) | 2001-03-05 | 2003-10-14 | Transvivo, Inc. | Apparatus and method for selective reduction of segmental intracellular and extracellular edema |
US6579460B1 (en) | 2001-03-13 | 2003-06-17 | Uop Llc | Process and composition for removing toxins from bodily fluids |
EP1383570A4 (en) | 2001-04-02 | 2006-12-27 | Hook Res Foundation | Programmable flexible-tube flow regulator and use methods |
US6572641B2 (en) | 2001-04-09 | 2003-06-03 | Nxstage Medical, Inc. | Devices for warming fluid and methods of use |
US20050020960A1 (en) | 2001-05-24 | 2005-01-27 | Brugger James M. | Blood treatment cartridge and blood processing machine with slot |
US6623470B2 (en) | 2001-06-27 | 2003-09-23 | Cleveland Clinic Foundation | Method and apparatus for controlling blood volume and hydration and for indicating resuscitation status of a patient using peripheral venous pressure as a hemodynamic parameter |
WO2003002181A2 (en) | 2001-06-29 | 2003-01-09 | A.B. Korkor Medical, Inc. | Catheter introducer having an expandable tip |
US6761063B2 (en) | 2001-07-02 | 2004-07-13 | Tobi Mengle | True position sensor for diaphragm valves |
US6572576B2 (en) | 2001-07-07 | 2003-06-03 | Nxstage Medical, Inc. | Method and apparatus for leak detection in a fluid line |
US6649063B2 (en) | 2001-07-12 | 2003-11-18 | Nxstage Medical, Inc. | Method for performing renal replacement therapy including producing sterile replacement fluid in a renal replacement therapy unit |
US20030010717A1 (en) | 2001-07-13 | 2003-01-16 | Nx Stage Medical, Inc. | Systems and methods for handling air and/or flushing fluids in a fluid circuit |
US6743193B2 (en) | 2001-07-17 | 2004-06-01 | Nx Stage Medical, Inc. | Hermetic flow selector valve |
US6517044B1 (en) | 2001-09-19 | 2003-02-11 | Delphi Technologies, Inc. | Soft-landing plunger for use in a control valve |
DE10152422C2 (en) | 2001-10-24 | 2003-08-21 | Lucas Automotive Gmbh | disc brake |
GB0126804D0 (en) | 2001-11-07 | 2002-01-02 | Univ London | Flow velocity measurement |
US7241272B2 (en) | 2001-11-13 | 2007-07-10 | Baxter International Inc. | Method and composition for removing uremic toxins in dialysis processes |
US6960179B2 (en) | 2001-11-16 | 2005-11-01 | National Quality Care, Inc | Wearable continuous renal replacement therapy device |
US7309323B2 (en) | 2001-11-16 | 2007-12-18 | National Quality Care, Inc. | Wearable continuous renal replacement therapy device |
US20060241543A1 (en) | 2001-11-16 | 2006-10-26 | National Quality Care, Inc. | Method for installing and servicing a wearable continuous renal replacement therapy device |
US6878283B2 (en) | 2001-11-28 | 2005-04-12 | Renal Solutions, Inc. | Filter cartridge assemblies and methods for filtering fluids |
US20030113932A1 (en) | 2001-12-14 | 2003-06-19 | Shmuel Sternberg | Hydrophobic ammonia sensing membrane |
US20030113931A1 (en) | 2001-12-14 | 2003-06-19 | Li Pan | Ammonia and ammonium sensors |
US6565395B1 (en) * | 2001-12-21 | 2003-05-20 | Northrop Grumman Corporation | Electrical connection to a coil spring through a local interference fit for connection to a vibratory rotation sensor and method of forming the same |
US20030128125A1 (en) | 2002-01-04 | 2003-07-10 | Burbank Jeffrey H. | Method and apparatus for machine error detection by combining multiple sensor inputs |
US7040142B2 (en) | 2002-01-04 | 2006-05-09 | Nxstage Medical, Inc. | Method and apparatus for leak detection in blood circuits combining external fluid detection and air infiltration detection |
US6796955B2 (en) | 2002-02-14 | 2004-09-28 | Chf Solutions, Inc. | Method to control blood and filtrate flowing through an extracorporeal device |
WO2003079887A2 (en) | 2002-03-21 | 2003-10-02 | Radiant Medical, Inc. | Measuring blood flow rate or cardiac output |
US7022098B2 (en) | 2002-04-10 | 2006-04-04 | Baxter International Inc. | Access disconnection systems and methods |
US10155082B2 (en) | 2002-04-10 | 2018-12-18 | Baxter International Inc. | Enhanced signal detection for access disconnection systems |
WO2003089926A2 (en) | 2002-04-19 | 2003-10-30 | Mission Medical, Inc. | Integrated automatic blood processing unit |
US20040167465A1 (en) | 2002-04-30 | 2004-08-26 | Mihai Dan M. | System and method for medical device authentication |
US20030216677A1 (en) | 2002-05-15 | 2003-11-20 | Li Pan | Biosensor for dialysis therapy |
US20030220606A1 (en) * | 2002-05-24 | 2003-11-27 | Don Busby | Compact housing for automated dialysis system |
US7175606B2 (en) | 2002-05-24 | 2007-02-13 | Baxter International Inc. | Disposable medical fluid unit having rigid frame |
US7153286B2 (en) | 2002-05-24 | 2006-12-26 | Baxter International Inc. | Automated dialysis system |
US6939111B2 (en) | 2002-05-24 | 2005-09-06 | Baxter International Inc. | Method and apparatus for controlling medical fluid pressure |
JP4396095B2 (en) | 2002-06-03 | 2010-01-13 | セイコーエプソン株式会社 | pump |
DE10224750A1 (en) | 2002-06-04 | 2003-12-24 | Fresenius Medical Care De Gmbh | Device for the treatment of a medical fluid |
US20050209547A1 (en) | 2002-06-06 | 2005-09-22 | Burbank Jeffrey H | Last-chance quality check and/or air/pathogen filter for infusion systems |
US6960328B2 (en) | 2002-07-15 | 2005-11-01 | Magnesium Elektron, Inc. | Zirconium phosphate and method of making same |
US7252767B2 (en) | 2002-07-15 | 2007-08-07 | Magnesium Elektron, Inc. | Hydrous zirconium oxide, hydrous hafnium oxide and method of making same |
US7238164B2 (en) | 2002-07-19 | 2007-07-03 | Baxter International Inc. | Systems, methods and apparatuses for pumping cassette-based therapies |
JP4066242B2 (en) | 2002-07-25 | 2008-03-26 | テルモ株式会社 | Peritoneal dialysis device and control method thereof |
MXPA05000816A (en) | 2002-07-19 | 2005-04-28 | Baxter Int | Systems and methods for performing peritoneal dialysis. |
US7112273B2 (en) | 2002-09-27 | 2006-09-26 | Nxstage Medical, Inc. | Volumetric fluid balance control for extracorporeal blood treatment |
US8182440B2 (en) * | 2002-09-27 | 2012-05-22 | Baxter International Inc. | Dialysis machine having combination display and handle |
US7351218B2 (en) | 2002-12-20 | 2008-04-01 | Gambro Lundia Ab | Device and process for extracorporeal treatment by citrate anticoagulant |
US9700663B2 (en) | 2005-01-07 | 2017-07-11 | Nxstage Medical, Inc. | Filtration system for preparation of fluids for medical applications |
US6872346B2 (en) | 2003-03-20 | 2005-03-29 | Nxstage Medical, Inc. | Method and apparatus for manufacturing filters |
US7135156B2 (en) | 2003-03-28 | 2006-11-14 | Baxter International Inc. | Method for processing a zirconium oxide composition in crystalline form |
US7452350B2 (en) | 2003-07-09 | 2008-11-18 | Yeakley Rourke M | Pre-dosed oral liquid medication dispensing system |
US7998101B2 (en) | 2003-07-28 | 2011-08-16 | Renal Solutions, Inc. | Devices and methods for body fluid flow control in extracorporeal fluid treatment |
KR100513102B1 (en) | 2003-08-28 | 2005-09-07 | 재단법인서울대학교산학협력재단 | Ac type anemometry and methods for data mapping of flow rate for the anemometry |
WO2005036039A1 (en) | 2003-10-03 | 2005-04-21 | Swagelok Company | Diaphragm monitoring for flow control devices |
EP1689466B1 (en) | 2003-10-31 | 2011-01-05 | Gambro Lundia AB | A circuit for extracorporeal blood treatment and flow-inverting device utilized therein |
US8038639B2 (en) | 2004-11-04 | 2011-10-18 | Baxter International Inc. | Medical fluid system with flexible sheeting disposable unit |
US8002727B2 (en) | 2003-11-07 | 2011-08-23 | Nxstage Medical, Inc. | Methods and apparatus for leak detection in blood processing systems |
CA2543500C (en) | 2003-11-07 | 2013-01-22 | Gambro Lundia Ab | Fluid distribution module and extracorporeal blood circuit including such a module |
US20050209563A1 (en) | 2004-03-19 | 2005-09-22 | Peter Hopping | Cassette-based dialysis medical fluid therapy systems, apparatuses and methods |
DE102004034337A1 (en) | 2004-04-14 | 2005-11-03 | Biotronik Gmbh & Co. Kg | Electrotherapy device |
JP4653170B2 (en) | 2004-06-09 | 2011-03-16 | リナル・ソリューションズ・インコーポレーテッド | Dialysis system |
KR100592049B1 (en) | 2004-07-16 | 2006-06-20 | 에스케이 텔레콤주식회사 | Terminal for Multimedia Ring Back Tone Service and Method for Controlling Terminal |
US7097148B2 (en) | 2004-07-21 | 2006-08-29 | Battelle Energy Alliance, Llc | Scissor thrust valve actuator |
DE602005009722D1 (en) | 2004-08-27 | 2008-10-23 | Koninkl Philips Electronics Nv | SYSTEM FOR LABELING A VISIBLE LABEL |
US20060064053A1 (en) | 2004-09-17 | 2006-03-23 | Bollish Stephen J | Multichannel coordinated infusion system |
WO2006049822A1 (en) | 2004-10-28 | 2006-05-11 | Nxstage Medical, Inc | Blood treatment dialyzer/filter design to trap entrained air in a fluid circuit |
US7059195B1 (en) | 2004-12-02 | 2006-06-13 | Honeywell International Inc. | Disposable and trimmable wireless pressure sensor for medical applications |
US7615028B2 (en) | 2004-12-03 | 2009-11-10 | Chf Solutions Inc. | Extracorporeal blood treatment and system having reversible blood pumps |
US7566432B2 (en) | 2004-12-28 | 2009-07-28 | Renal Solutions, Inc. | Method of synthesizing zirconium phosphate particles |
US7935074B2 (en) | 2005-02-28 | 2011-05-03 | Fresenius Medical Care Holdings, Inc. | Cassette system for peritoneal dialysis machine |
US20060195064A1 (en) * | 2005-02-28 | 2006-08-31 | Fresenius Medical Care Holdings, Inc. | Portable apparatus for peritoneal dialysis therapy |
US20060226086A1 (en) | 2005-04-08 | 2006-10-12 | Robinson Thomas C | Centrifuge for blood processing systems |
US7405572B2 (en) | 2005-05-02 | 2008-07-29 | Invensys Systems, Inc. | Non-metallic flow-through electrodeless conductivity sensor and leak detector |
JP5214438B2 (en) | 2005-05-06 | 2013-06-19 | クアンタ フルーイド ソリューションズ リミテッド | Fluid processing equipment |
US7922899B2 (en) | 2005-06-09 | 2011-04-12 | Gambro Lundia Ab | Medical apparatus and method for setting up a medical apparatus |
JP5158830B2 (en) | 2005-06-22 | 2013-03-06 | 日機装株式会社 | Dialysis treatment device |
US7337674B2 (en) | 2005-06-29 | 2008-03-04 | Nx Stage Medical, Inc. | Pressure detector for fluid circuits |
US8197231B2 (en) | 2005-07-13 | 2012-06-12 | Purity Solutions Llc | Diaphragm pump and related methods |
BRPI0614083A2 (en) | 2005-08-05 | 2011-03-09 | Nat Quality Care Inc | dual channel pulsating pump and fully portable artificial kidney device (rap) |
EP1917053B8 (en) | 2005-08-25 | 2011-01-19 | Gambro Lundia AB | Medical apparatus |
WO2007028056A2 (en) * | 2005-09-02 | 2007-03-08 | Advanced Renal Therapies, Inc. | Extracorporeal renal dialysis system |
US7146861B1 (en) | 2005-10-18 | 2006-12-12 | Honeywell International Inc. | Disposable and trimmable wireless pressure sensor |
US8021319B2 (en) | 2005-10-27 | 2011-09-20 | Gambro Lundia Ab | Extracorporeal blood set |
EP1957841A1 (en) | 2005-11-22 | 2008-08-20 | Norgren, Inc. | Valve with sensor |
EP1969265B1 (en) | 2005-12-15 | 2015-09-16 | DD Operations Ltd. | Digital flow control |
CN101341489B (en) | 2005-12-19 | 2012-10-03 | 甘布罗伦迪亚股份公司 | Medical apparatus with improved user interface |
JP4171021B2 (en) | 2005-12-21 | 2008-10-22 | 株式会社フジキン | Water hammerless valve |
WO2007073739A1 (en) * | 2005-12-29 | 2007-07-05 | Flexdialysis Aps | Method and apparatus for home dialysis |
CN101394875B (en) | 2006-01-06 | 2011-04-20 | 雷纳尔解决方法公司 | Dual purpose acute and home treatment dialysis machine |
US8409864B2 (en) | 2006-01-06 | 2013-04-02 | Renal Solutions, Inc. | Ammonia sensor and system for use |
US7713226B2 (en) | 2006-01-06 | 2010-05-11 | Renal Solutions, Inc. | On demand and post-treatment delivery of saline to a dialysis patient |
EP1974302A1 (en) | 2006-01-06 | 2008-10-01 | Renal Solutions, Inc. | Dialysis machine with transport mode |
US7981280B2 (en) | 2006-01-06 | 2011-07-19 | Renal Solutions, Inc. | Recirculation of blood in an extracorporeal blood treatment system |
JP3126509U (en) | 2006-04-06 | 2006-11-02 | 誠治 松本 | Simple urine pack alarm device |
US20140199193A1 (en) | 2007-02-27 | 2014-07-17 | Deka Products Limited Partnership | Blood treatment systems and methods |
MX2008013266A (en) | 2006-04-14 | 2008-10-27 | Deka Products Lp | Systems, devices and methods for fluid pumping, heat exchange, thermal sensing, and conductivity sensing. |
US8226595B2 (en) | 2006-05-26 | 2012-07-24 | Baxter International Inc. | Automated dialysis system driven by gravity and vacuum |
GB0613662D0 (en) | 2006-07-10 | 2006-08-16 | Rotork Controls | Improvements to valve actuators |
US7887502B2 (en) | 2006-09-15 | 2011-02-15 | University Of Florida Research Foundation, Inc. | Method for using photoplethysmography to optimize fluid removal during renal replacement therapy by hemodialysis or hemofiltration |
US8708943B2 (en) | 2006-10-30 | 2014-04-29 | Gambro Lundia Ab | Hemo(dia) filtration apparatus |
WO2008064174A1 (en) | 2006-11-17 | 2008-05-29 | National Quality Care, Inc. | Enhanced clearance in an artificial kidney incorporating a pulsatile pump |
US7270015B1 (en) | 2006-11-29 | 2007-09-18 | Murray F Feller | Thermal pulsed ultrasonic flow sensor |
US8449487B2 (en) | 2006-12-01 | 2013-05-28 | Gambro Lundia Ab | Blood treatment apparatus |
US20080149563A1 (en) | 2006-12-22 | 2008-06-26 | Renal Solutions, Inc. | Method of controlling dialysis using blood circulation times |
US20080161751A1 (en) * | 2006-12-29 | 2008-07-03 | Plahey Kulwinder S | Peritoneal dialysis therapy validation |
WO2008089766A1 (en) | 2007-01-26 | 2008-07-31 | Diramo A/S | Analysis system with a remote analysing unit |
US8152751B2 (en) | 2007-02-09 | 2012-04-10 | Baxter International Inc. | Acoustic access disconnection systems and methods |
US8357298B2 (en) | 2007-02-27 | 2013-01-22 | Deka Products Limited Partnership | Hemodialysis systems and methods |
US8562834B2 (en) * | 2007-02-27 | 2013-10-22 | Deka Products Limited Partnership | Modular assembly for a portable hemodialysis system |
US8491184B2 (en) | 2007-02-27 | 2013-07-23 | Deka Products Limited Partnership | Sensor apparatus systems, devices and methods |
US20080253911A1 (en) * | 2007-02-27 | 2008-10-16 | Deka Products Limited Partnership | Pumping Cassette |
CN103845768B (en) | 2007-02-27 | 2016-09-28 | 德卡产品有限公司 | Hemodialysis system and method |
US8409441B2 (en) | 2007-02-27 | 2013-04-02 | Deka Products Limited Partnership | Blood treatment systems and methods |
JP5041847B2 (en) | 2007-03-30 | 2012-10-03 | 旭有機材工業株式会社 | Fluid control device |
EP2133107A4 (en) | 2007-03-30 | 2015-04-15 | Jms Co Ltd | Blood circuit, blood purification control apparatus, and priming method |
DE102007018362A1 (en) | 2007-04-18 | 2008-10-30 | Fresenius Medical Care Deutschland Gmbh | Method for preparing a treatment machine and treatment machine |
US7387022B1 (en) | 2007-05-02 | 2008-06-17 | Honeywell International Inc. | Thermal mass flow transducer including PWM-type heater current driver |
DE102007020573B4 (en) | 2007-05-02 | 2014-12-04 | Fresenius Medical Care Deutschland Gmbh | Hose roller pump |
US7628378B2 (en) | 2007-05-22 | 2009-12-08 | Fema Corporation Of Michigan | Proportional solenoid with armature motion sensing |
JP2008291911A (en) | 2007-05-24 | 2008-12-04 | Alps Electric Co Ltd | Valve device |
JP4362853B2 (en) | 2007-06-18 | 2009-11-11 | Smc株式会社 | 2-port solenoid valve |
US7896863B2 (en) | 2007-06-27 | 2011-03-01 | Tyco Healthcare Group Lp | Positive displacement fluid lock port |
US7809254B2 (en) | 2007-07-05 | 2010-10-05 | Baxter International Inc. | Dialysis fluid heating using pressure and vacuum |
US7901376B2 (en) | 2007-07-05 | 2011-03-08 | Baxter International Inc. | Dialysis cassette having multiple outlet valve |
US8078333B2 (en) | 2007-07-05 | 2011-12-13 | Baxter International Inc. | Dialysis fluid heating algorithms |
US7909795B2 (en) | 2007-07-05 | 2011-03-22 | Baxter International Inc. | Dialysis system having disposable cassette and interface therefore |
US7981082B2 (en) | 2007-08-21 | 2011-07-19 | Hospira, Inc. | System and method for reducing air bubbles in a fluid delivery line |
US9308307B2 (en) | 2007-09-13 | 2016-04-12 | Fresenius Medical Care Holdings, Inc. | Manifold diaphragms |
US20090101577A1 (en) | 2007-09-28 | 2009-04-23 | Fulkerson Barry N | Methods and Systems for Controlling Ultrafiltration Using Central Venous Pressure Measurements |
US9358331B2 (en) | 2007-09-13 | 2016-06-07 | Fresenius Medical Care Holdings, Inc. | Portable dialysis machine with improved reservoir heating system |
US8597505B2 (en) | 2007-09-13 | 2013-12-03 | Fresenius Medical Care Holdings, Inc. | Portable dialysis machine |
US8475399B2 (en) | 2009-02-26 | 2013-07-02 | Fresenius Medical Care Holdings, Inc. | Methods and systems for measuring and verifying additives for use in a dialysis machine |
US20090076434A1 (en) | 2007-09-13 | 2009-03-19 | Mischelevich David J | Method and System for Achieving Volumetric Accuracy in Hemodialysis Systems |
US8535522B2 (en) | 2009-02-12 | 2013-09-17 | Fresenius Medical Care Holdings, Inc. | System and method for detection of disconnection in an extracorporeal blood circuit |
US20090114037A1 (en) | 2007-10-11 | 2009-05-07 | Mark Forrest Smith | Photo-Acoustic Flow Meter |
US8240636B2 (en) | 2009-01-12 | 2012-08-14 | Fresenius Medical Care Holdings, Inc. | Valve system |
WO2009039357A2 (en) * | 2007-09-19 | 2009-03-26 | Fresenius Medical Care Holdings, Inc. | Dialysis systems and related components |
KR20090030923A (en) | 2007-09-21 | 2009-03-25 | 삼성전자주식회사 | Method and apparatus for configuring and playing contents in a portable terminal |
US7755488B2 (en) | 2007-09-21 | 2010-07-13 | Baxter International Inc. | Access disconnection detection system |
US8187184B2 (en) | 2007-09-21 | 2012-05-29 | Baxter International, Inc. | Access disconnect system with optical and other sensors |
US8221320B2 (en) | 2007-09-21 | 2012-07-17 | Baxter International Inc. | Access disconnect detection system |
US8197431B2 (en) | 2007-09-21 | 2012-06-12 | Baxter International Inc. | Acoustic access disconnect detection system |
US7995816B2 (en) | 2007-09-24 | 2011-08-09 | Baxter International Inc. | Detecting access disconnect by pattern recognition |
US8083677B2 (en) | 2007-09-24 | 2011-12-27 | Baxter International Inc. | Access disconnect detection using glucose |
US7892331B2 (en) | 2007-10-01 | 2011-02-22 | Baxter International Inc. | Dialysis systems having air separation chambers with internal structures to enhance air removal |
ES2358854T3 (en) | 2007-10-03 | 2011-05-16 | Gambro Lundia Ab | MEDICAL DEVICE. |
US20090120864A1 (en) | 2007-10-05 | 2009-05-14 | Barry Neil Fulkerson | Wearable dialysis methods and devices |
KR101973034B1 (en) | 2007-10-12 | 2019-04-26 | 데카 프로덕츠 리미티드 파트너쉽 | Apparatus and method for hemodialysis |
US20090112507A1 (en) | 2007-10-29 | 2009-04-30 | Edney Daniel B | Fluid probe |
US20090112155A1 (en) | 2007-10-30 | 2009-04-30 | Lifescan, Inc. | Micro Diaphragm Pump |
US20090113335A1 (en) | 2007-10-30 | 2009-04-30 | Baxter International Inc. | Dialysis system user interface |
US9415150B2 (en) | 2007-11-09 | 2016-08-16 | Baxter Healthcare S.A. | Balanced flow dialysis machine |
US8889004B2 (en) | 2007-11-16 | 2014-11-18 | Fresenius Medical Care Holdings, Inc. | Dialysis systems and methods |
JP5409645B2 (en) | 2007-11-16 | 2014-02-05 | フレセニウス メディカル ケア ホールディングス インコーポレーテッド | Dialysis system |
WO2009067143A1 (en) | 2007-11-20 | 2009-05-28 | Flowserve Management Company | Upset resistant mechanical seal |
DE102007056237A1 (en) | 2007-11-22 | 2009-05-28 | Fresenius Medical Care Deutschland Gmbh | Dialysis tank with heated dialysate tank and appropriate dialysis system and method |
US8038640B2 (en) | 2007-11-26 | 2011-10-18 | Purity Solutions Llc | Diaphragm pump and related systems and methods |
JP2011509760A (en) | 2008-01-18 | 2011-03-31 | エックスコーポリアル、 インコーポレイテッド | Carbon dioxide gas removal from fluid circuit of dialysis machine |
EP2252346B1 (en) | 2008-01-23 | 2016-04-06 | DEKA Products Limited Partnership | Disposable components for fluid line autoconnect systems and methods |
US8034235B2 (en) | 2008-02-14 | 2011-10-11 | Baxter International Inc. | Dialysis system including supplemental power source |
US7892423B2 (en) | 2008-02-14 | 2011-02-22 | Baxter International Inc. | Dialysis system including multi-heater power coordination |
WO2009123729A1 (en) | 2008-04-02 | 2009-10-08 | The Trustees Of The University Of Pennsylvania | Dual lumen dialysis catheter with internally bored or externally-grooved small bore |
US20110087187A1 (en) | 2008-04-30 | 2011-04-14 | Gambro Lundia Ab | Hydrophobic deaeration membrane |
KR20090118536A (en) | 2008-05-14 | 2009-11-18 | 탑엠앤에이 주식회사 | Blood dialyzing apparatus |
ES2446543T3 (en) | 2008-05-26 | 2014-03-10 | Gambro Lundia Ab | Hemodialysis machine or heme (day) filtration |
US7988849B2 (en) | 2008-06-03 | 2011-08-02 | Baxter International Inc. | Customizable personal dialysis device having ease of use and therapy enhancement features |
DE102008026708B4 (en) | 2008-06-04 | 2014-01-23 | Iprm Intellectual Property Rights Management Ag | Device for determining the blood volume and / or blood volume flow and method for operating the same |
US9180238B2 (en) | 2008-06-11 | 2015-11-10 | Baxter International Inc. | Distributed processing system and method for dialysis machines |
US8342478B1 (en) | 2008-06-16 | 2013-01-01 | Tri-Tec Manufacturing, LLC | Valve actuator assembly and methods of using the same |
NZ590471A (en) | 2008-06-23 | 2013-04-26 | Temasek Polytechnic | A FLOW SYSTEM OF A PORTABLE DIALYSIS DEVICE with a peritoneal cavity dialysate conduit, pump for both inflow and outflow, valves, sorbent and storage chamber. |
ITMI20081144A1 (en) | 2008-06-25 | 2009-12-26 | Gambro Lundia Ab | USER INTERFACE FOR MONITORING THE STATUS OF MEDICAL MACHINES |
US8715216B2 (en) | 2008-06-26 | 2014-05-06 | Gambro Lundia Ab | Method and device for processing a time-dependent measurement signal |
US8062513B2 (en) | 2008-07-09 | 2011-11-22 | Baxter International Inc. | Dialysis system and machine having therapy prescription recall |
IT1391555B1 (en) | 2008-07-16 | 2012-01-11 | Gambro Lundia Ab | EXTRACORPOREO BLOOD TREATMENT SYSTEM |
US8696626B2 (en) | 2008-07-30 | 2014-04-15 | Claudia F. E. Kirsch | Debubbler |
DE102008039022B4 (en) | 2008-08-21 | 2014-08-28 | Fresenius Medical Care Deutschland Gmbh | A method and apparatus for monitoring a peristaltic peristaltic pump for delivering a fluid in a tubing |
WO2010029401A2 (en) | 2008-09-09 | 2010-03-18 | Gambro Lundia Ab | A procedure and a device for extracorporeal blood treatment using citrate anticoagulation |
US20100184198A1 (en) | 2009-01-16 | 2010-07-22 | Joseph Russell T | Systems and Methods of Urea Processing to Reduce Sorbent Load |
US8409444B2 (en) | 2008-09-30 | 2013-04-02 | Fresenius Medical Care Holdings, Inc. | Acid zirconium phosphate and alkaline hydrous zirconium oxide materials for sorbent dialysis |
CA3076044A1 (en) | 2008-09-30 | 2010-04-08 | Fresenius Medical Care Holdings, Inc. | Covalently immobilized enzyme and method to make the same |
CN102239113B (en) | 2008-10-03 | 2013-11-06 | 弗雷塞尼斯医疗保健控股公司 | Zirconium phosphate particles having improved adsorption capacity and method of synthesizing the same |
FR2936713B1 (en) | 2008-10-06 | 2012-01-27 | Rd Nephrologie | EXTRACORPOREAL BLOOD TREATMENT APPARATUS AND METHOD FOR MANAGING SUCH APPARATUS. |
WO2010042667A2 (en) | 2008-10-07 | 2010-04-15 | Xcorporeal, Inc. | Thermal flow meter |
CN105148344B (en) | 2008-10-07 | 2019-06-11 | 弗雷塞尼斯医疗保健控股公司 | System and method are charged for dialysis system |
US8293114B2 (en) | 2008-10-10 | 2012-10-23 | Gambro Lundia Ab | Heat exchanger and method for heat exchanging |
DE102008051541B4 (en) | 2008-10-14 | 2010-09-09 | Fresenius Medical Care Deutschland Gmbh | Method and device for checking the supply of substitution fluid upstream or downstream of a dialyzer or filter of an extracorporeal blood treatment device |
NZ614023A (en) | 2008-10-30 | 2014-11-28 | Fresenius Med Care Hldg Inc | Modular, portable dialysis system |
JP5294985B2 (en) | 2008-12-16 | 2013-09-18 | 日機装株式会社 | Blood purification apparatus and priming method thereof |
ATE524205T1 (en) | 2009-02-11 | 2011-09-15 | Braun B Avitum Ag | DEVICE FOR EXTRACORPORATE BLOOD TREATMENT |
US8192401B2 (en) | 2009-03-20 | 2012-06-05 | Fresenius Medical Care Holdings, Inc. | Medical fluid pump systems and related components and methods |
WO2010114932A1 (en) | 2009-03-31 | 2010-10-07 | Xcorporeal, Inc. | Modular reservoir assembly for a hemodialysis and hemofiltration system |
US8315885B2 (en) | 2009-04-14 | 2012-11-20 | Baxter International Inc. | Therapy management development platform |
US8801922B2 (en) | 2009-06-24 | 2014-08-12 | State Of Oregon Acting By And Through The State Board Of Higher Education On Behalf Of Oregon State University | Dialysis system |
EP3025740B1 (en) | 2009-08-04 | 2020-09-02 | Fresenius Medical Care Holdings, Inc. | Dialysis systems, components, and methods |
US9072540B2 (en) | 2009-08-12 | 2015-07-07 | Boston Scientific Limited | Adaptive tubing cassettes for use in connection with interventional catheter assemblies |
US20110054352A1 (en) | 2009-08-25 | 2011-03-03 | Po-Jen Ko | Portable Dialysis Access Monitor Device |
US20110083746A1 (en) | 2009-10-09 | 2011-04-14 | Cameron International Corporation | Smart valve utilizing a force sensor |
US9020827B2 (en) | 2009-10-16 | 2015-04-28 | Baxter International Inc. | Peritoneal dialysis optimized using a patient hand-held scanning device |
US8460228B2 (en) | 2009-10-27 | 2013-06-11 | Nxstage Medical Inc. | Methods, devices, and systems for parallel control of infusion device |
MX353433B (en) | 2009-10-30 | 2018-01-11 | Deka Products Lp | Apparatus and method for detecting disconnection of an intravascular access device. |
DE102009051805A1 (en) | 2009-11-03 | 2011-05-05 | Gambro Lundia Ab | Dialysis devices with piezo pumps |
US8877061B2 (en) | 2009-11-06 | 2014-11-04 | Gloria Lovell | Dialyzer with dual safety valves |
WO2011069110A1 (en) | 2009-12-05 | 2011-06-09 | Home Dialysis Plus, Ltd. | Modular dialysis system |
US8753515B2 (en) | 2009-12-05 | 2014-06-17 | Home Dialysis Plus, Ltd. | Dialysis system with ultrafiltration control |
US8366649B2 (en) | 2009-12-09 | 2013-02-05 | Araz Ibragimov | Manually operated disposable single-needle circuit for extracorporeal treatment of blood |
US9554756B2 (en) | 2009-12-15 | 2017-01-31 | Shenzhen Mindray Bio-Medical Electronics Co. Ltd. | Systems and methods for customizing a multiple alarm system in a portable patient monitor |
US20110141116A1 (en) | 2009-12-16 | 2011-06-16 | Baxter International Inc. | Methods and apparatus for displaying flow rate graphs and alarms on a dialysis system |
CN105251072B (en) | 2009-12-24 | 2017-08-25 | 昆山韦睿医疗科技有限公司 | A kind of dialysis system |
CN201600175U (en) | 2009-12-28 | 2010-10-06 | 上海高衡电子有限公司 | Electromagnetic sensor elastomer |
US20110155657A1 (en) | 2009-12-30 | 2011-06-30 | Nephros, Inc. | Tee-connector for use in a filtration system |
US8096186B2 (en) | 2010-03-24 | 2012-01-17 | Carefusion 303, Inc. | Systems and methods for measuring fluid pressure within a disposable IV set connected to a fluid supply pump |
US9002655B2 (en) | 2010-05-03 | 2015-04-07 | Gambro Lundia Ab | Medical apparatus for extracorporeal blood treatment and method for determining a blood parameter value in a medical apparatus thereof |
US20110272337A1 (en) | 2010-05-04 | 2011-11-10 | C-Tech Biomedical, Inc. | Dual mode hemodialysis machine |
WO2011140389A2 (en) | 2010-05-05 | 2011-11-10 | C-Tech Biomedical, Inc. | Membrane electrolyzer and hemodialysis system using the same |
CN103068417A (en) | 2010-06-02 | 2013-04-24 | 阿尔佛雷德·R·扎拉特 | Hemodialysis system and method |
US8501009B2 (en) | 2010-06-07 | 2013-08-06 | State Of Oregon Acting By And Through The State Board Of Higher Education On Behalf Of Oregon State University | Fluid purification system |
US8567235B2 (en) | 2010-06-29 | 2013-10-29 | Baxter International Inc. | Tube measurement technique using linear actuator and pressure sensor |
US9069886B2 (en) | 2010-09-29 | 2015-06-30 | Terumo Kabushiki Kaisha | Home medical apparatus |
US8316725B2 (en) | 2010-12-15 | 2012-11-27 | Honeywell International Inc. | Force sensor |
US8690855B2 (en) | 2010-12-22 | 2014-04-08 | Medtronic Minimed, Inc. | Fluid reservoir seating procedure for a fluid infusion device |
US9581331B2 (en) | 2011-02-21 | 2017-02-28 | Emerson Electric Co. | Control of stepper motor operated gas valve |
EP3165245B1 (en) | 2011-08-02 | 2019-02-20 | Medtronic, Inc. | Hemodialysis system having a flow path with a controlled compliant volume |
JP5338885B2 (en) | 2011-11-10 | 2013-11-13 | Smc株式会社 | Pinch valve |
DE102011120166A1 (en) | 2011-12-06 | 2013-06-06 | Micronas Gmbh | Magnetic pressure sensor |
US8783652B2 (en) | 2012-03-12 | 2014-07-22 | Mps Corporation | Liquid flow control for film deposition |
US9157786B2 (en) | 2012-12-24 | 2015-10-13 | Fresenius Medical Care Holdings, Inc. | Load suspension and weighing system for a dialysis machine reservoir |
EP3524286B1 (en) | 2012-12-24 | 2021-03-03 | Fresenius Medical Care Holdings, Inc. | Portable dialysis machine with pump shoe having elevated sides |
US9354640B2 (en) | 2013-11-11 | 2016-05-31 | Fresenius Medical Care Holdings, Inc. | Smart actuator for valve |
-
2009
- 2009-10-30 NZ NZ614023A patent/NZ614023A/en unknown
- 2009-10-30 MX MX2011004600A patent/MX2011004600A/en active IP Right Grant
- 2009-10-30 MX MX2015004503A patent/MX347636B/en unknown
- 2009-10-30 CN CN200980153428.7A patent/CN102639201B/en active Active
- 2009-10-30 JP JP2011534821A patent/JP5628186B2/en active Active
- 2009-10-30 CA CA2928208A patent/CA2928208A1/en not_active Abandoned
- 2009-10-30 NZ NZ592652A patent/NZ592652A/en unknown
- 2009-10-30 EA EA201170628A patent/EA024555B1/en not_active IP Right Cessation
- 2009-10-30 WO PCT/US2009/062840 patent/WO2010062698A2/en active Application Filing
- 2009-10-30 BR BRPI0921637A patent/BRPI0921637A2/en not_active IP Right Cessation
- 2009-10-30 AU AU2009320007A patent/AU2009320007B2/en active Active
- 2009-10-30 CN CN201510391794.3A patent/CN105056324B/en active Active
- 2009-10-30 CA CA2739807A patent/CA2739807C/en active Active
- 2009-10-30 US US12/610,032 patent/US10035103B2/en active Active
- 2009-10-30 EP EP09829649.4A patent/EP2342003B1/en active Active
- 2009-10-30 EA EA201690595A patent/EA201690595A1/en unknown
- 2009-10-30 KR KR1020117009889A patent/KR101508483B1/en active IP Right Grant
-
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- 2013-01-17 HK HK13100743.5A patent/HK1173693A1/en not_active IP Right Cessation
-
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- 2014-10-01 JP JP2014203093A patent/JP6165696B2/en active Active
-
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- 2017-06-21 JP JP2017121399A patent/JP6980424B2/en active Active
-
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- 2018-05-22 US US15/985,869 patent/US10758868B2/en active Active
-
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- 2019-10-09 JP JP2019185844A patent/JP7069097B2/en active Active
-
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- 2020-07-07 US US16/922,779 patent/US20200406193A1/en not_active Abandoned
Patent Citations (101)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3242456A (en) * | 1963-10-07 | 1966-03-22 | Itt | Electrical connector with spring pin contact |
US3709222A (en) * | 1970-12-28 | 1973-01-09 | Sarns Inc | Method and apparatus for automatic peritoneal dialysis |
US3946731A (en) * | 1971-01-20 | 1976-03-30 | Lichtenstein Eric Stefan | Apparatus for extracorporeal treatment of blood |
US4430098A (en) * | 1976-03-24 | 1984-02-07 | Bowman Donald B | Apparatus for degassing hemodialysis liquid and the like |
US5876419A (en) * | 1976-10-02 | 1999-03-02 | Navius Corporation | Stent and method for making a stent |
US4071444A (en) * | 1976-10-12 | 1978-01-31 | Purdue Research Foundation | Portable chemical reactor for use as an artificial kidney |
US4247393A (en) * | 1979-01-11 | 1981-01-27 | Wallace Richard A | Hemodialysis assist device |
US4368737A (en) * | 1980-07-07 | 1983-01-18 | Purdue Research Foundation | Implantable catheter |
US4563170A (en) * | 1982-07-30 | 1986-01-07 | Karl Aigner | Device for in vivo purification of blood |
US4498902A (en) * | 1982-11-13 | 1985-02-12 | Purdue Research Foundation | Catheter guide |
US4806247A (en) * | 1985-04-12 | 1989-02-21 | Baxter International Inc. | Plasmapheresis system and method |
US4990258A (en) * | 1985-06-04 | 1991-02-05 | Gambro Ab | Monitor for the control and/or checking of two or more functions |
US5198335A (en) * | 1985-06-04 | 1993-03-30 | Fuji Photo Film Co., Ltd. | Integral multilayer analytical element for analysis of ammonia-forming substrate |
US4909713A (en) * | 1986-05-07 | 1990-03-20 | Cobe Laboratories, Inc. | Peristaltic pump |
US5002054A (en) * | 1987-02-25 | 1991-03-26 | Ash Medical Systems, Inc. | Interstitial filtration and collection device and method for long-term monitoring of physiological constituents of the body |
US4897189A (en) * | 1987-10-23 | 1990-01-30 | Research Corporation Limited | Blood purification apparatus |
US4997570A (en) * | 1988-11-04 | 1991-03-05 | Fresenius Ag | Method and device for ultrafiltration during hemodialysis |
US4995268A (en) * | 1989-09-01 | 1991-02-26 | Ash Medical System, Incorporated | Method and apparatus for determining a rate of flow of blood for an extracorporeal blood therapy instrument |
US5100554A (en) * | 1989-11-21 | 1992-03-31 | Fresenius Ag | Method for the in-vivo determination of hemodialysis parameters |
US6200485C1 (en) * | 1991-10-11 | 2002-05-21 | Childrens Hosp Medical Center | Hemofiltration system and method |
US6200485B1 (en) * | 1991-10-11 | 2001-03-13 | Chidren's Hospital Medical Center | Hemofiltration system and method |
US5295505A (en) * | 1991-11-28 | 1994-03-22 | Fresenius Ag | Apparatus for preparation of a medicinal solution |
US5277820A (en) * | 1992-02-06 | 1994-01-11 | Hemocleanse, Inc. | Device and method for extracorporeal blood treatment |
US5284559A (en) * | 1992-06-16 | 1994-02-08 | Rhode Island Hospital | Preparative electrophoresis device and method |
US6348162B1 (en) * | 1992-09-04 | 2002-02-19 | Viacirq, Inc. | Starting dialysate composition for use as an initial dialysate in hemo dialysis |
US5284470A (en) * | 1992-11-02 | 1994-02-08 | Beltz Alex D | Wearable, portable, light-weight artificial kidney |
US5391143A (en) * | 1993-03-12 | 1995-02-21 | Kensey Nash Corporation | Method and system for effecting weight reduction of living beings |
US5385005A (en) * | 1993-07-12 | 1995-01-31 | Ash; Stephen C. | Lawn trimmer/edge attachment |
USD355816S (en) * | 1993-11-17 | 1995-02-28 | Ash Stephen C | Trimmer attachment |
US6196922B1 (en) * | 1994-02-10 | 2001-03-06 | Netzsch Mohnopumpen Gmbh | Universal joint coupling in particular arranged on a universal joint shaft of an eccentric worm machine |
US5614677A (en) * | 1994-06-03 | 1997-03-25 | Fresenius Ag | Diaphragm gage for measuring the pressure of a fluid |
US5725773A (en) * | 1994-11-12 | 1998-03-10 | Fresenius Ag | Method and apparatus for determining the quantity of oremic toxins removed by a hemodialysis treatment |
US5713850A (en) * | 1994-12-09 | 1998-02-03 | Fresenius Ag | Apparatus for controlling a fluid flow |
US5725776A (en) * | 1995-02-13 | 1998-03-10 | Aksys, Ltd. | Methods for ultrafiltration control in hemodialysis |
US6196992B1 (en) * | 1995-05-23 | 2001-03-06 | Baxter International Inc. | Portable pump apparatus for continuous ambulatory peritoneal dialysis and a method for providing same |
US5609770A (en) * | 1995-06-07 | 1997-03-11 | Cobe Laboratories, Inc. | Graphical operator machine interface and method for information entry and selection in a dialysis machine |
US5711883A (en) * | 1995-09-27 | 1998-01-27 | Fresenius Usa, Inc. | Method for testing dialyzer integrity prior to use |
US6841172B1 (en) * | 1996-08-14 | 2005-01-11 | Hemocleanse, Inc. | Method for iron delivery to a patient by transfer from dialysate |
US5858186A (en) * | 1996-12-20 | 1999-01-12 | The Regents Of The University Of California | Urea biosensor for hemodialysis monitoring |
US6673314B1 (en) * | 1997-02-14 | 2004-01-06 | Nxstage Medical, Inc. | Interactive systems and methods for supporting hemofiltration therapies |
US6852090B2 (en) * | 1997-02-14 | 2005-02-08 | Nxstage Medical, Inc. | Fluid processing systems and methods using extracorporeal fluid flow panels oriented within a cartridge |
US6190349B1 (en) * | 1997-08-06 | 2001-02-20 | Hemocleanse, Inc. | Splittable multiple catheter assembly and methods for inserting the same |
US6042561A (en) * | 1997-10-22 | 2000-03-28 | Ash Medical Systems, Inc. | Non-intravascular infusion access device |
US7004924B1 (en) * | 1998-02-11 | 2006-02-28 | Nxstage Medical, Inc. | Methods, systems, and kits for the extracorporeal processing of blood |
US20030012905A1 (en) * | 1998-02-13 | 2003-01-16 | Zumbrum Michael Allen | Flexure endurant composite elastomer compositions |
US6517045B1 (en) * | 1998-10-02 | 2003-02-11 | Ronald Northedge | Valve assembly |
US6695803B1 (en) * | 1998-10-16 | 2004-02-24 | Mission Medical, Inc. | Blood processing system |
US6168578B1 (en) * | 1999-02-18 | 2001-01-02 | Melvin Diamond | Portable kidney dialysis system |
US6607495B1 (en) * | 1999-06-18 | 2003-08-19 | University Of Virginia Patent Foundation | Apparatus for fluid transport and related method thereof |
US6681624B2 (en) * | 1999-12-15 | 2004-01-27 | Mitsui Mining & Smelting Co., Ltd. | Thermal flowmeter with fluid descriminant function |
US20030056585A1 (en) * | 1999-12-15 | 2003-03-27 | Shinya Furuki | Thermal flowmeter with fluid descriminant function |
US6706007B2 (en) * | 2000-12-29 | 2004-03-16 | Chf Solutions, Inc. | Feedback control of ultrafiltration to prevent hypotension |
US7175809B2 (en) * | 2000-12-29 | 2007-02-13 | Chf Solutions Inc. | Feedback control of ultrafiltration to prevent hypotension |
US7886611B2 (en) * | 2001-04-13 | 2011-02-15 | Chf Solutions Inc. | Pressure sensor disconnect detection for a blood treatment device |
US6685664B2 (en) * | 2001-06-08 | 2004-02-03 | Chf Solutions, Inc. | Method and apparatus for ultrafiltration utilizing a long peripheral access venous cannula for blood withdrawal |
US6702561B2 (en) * | 2001-07-12 | 2004-03-09 | Nxstage Medical, Inc. | Devices for potting a filter for blood processing |
US6690280B2 (en) * | 2001-09-07 | 2004-02-10 | Richard A. Citrenbaum | Apparatus and process for infusion monitoring |
US20030048185A1 (en) * | 2001-09-07 | 2003-03-13 | Citrenbaum, M.D. Richard A. | Apparatus and process for infusion monitoring |
US6843779B1 (en) * | 2001-09-17 | 2005-01-18 | Mirimedical, Llc | Hemodialysis system |
US7494590B2 (en) * | 2001-10-02 | 2009-02-24 | Gambro Lundia Ab | Method of controlling a dialysis apparatus |
US20100022936A1 (en) * | 2001-11-16 | 2010-01-28 | National Quality Care, Inc. | Wearable ultrafiltration device |
US20080021366A1 (en) * | 2001-11-16 | 2008-01-24 | National Quality Care, Inc | Wearable ultrafiltration device |
US7645253B2 (en) * | 2001-11-16 | 2010-01-12 | National Quality Care, Inc. | Wearable ultrafiltration device |
US20080051689A1 (en) * | 2001-11-16 | 2008-02-28 | National Quality Care, Inc. | Wearable ultrafiltration device |
US7317967B2 (en) * | 2001-12-31 | 2008-01-08 | B. Braun Medical Inc. | Apparatus and method for transferring data to a pharmaceutical compounding system |
US20040031756A1 (en) * | 2002-07-19 | 2004-02-19 | Terumo Kabushiki Kaisha | Peritoneal dialysis apparatus and control method thereof |
US20040021108A1 (en) * | 2002-07-30 | 2004-02-05 | Siemens-Elema Ab | Valve assembly |
US20080006570A1 (en) * | 2003-01-23 | 2008-01-10 | National Quality Care, Inc. | Low hydraulic resistance cartridge |
US7169303B2 (en) * | 2003-05-28 | 2007-01-30 | Hemocleanse Technologies, Llc | Sorbent reactor for extracorporeal blood treatment systems, peritoneal dialysis systems, and other body fluid treatment systems |
US20050070837A1 (en) * | 2003-09-25 | 2005-03-31 | Gambro Lundia Ab. | User interface for an extracorporeal blood treatment machine |
US7174613B2 (en) * | 2003-10-14 | 2007-02-13 | Dreamwell Ltd | Method for manufacturing a foam core having channel cuts |
US20110000832A1 (en) * | 2003-11-05 | 2011-01-06 | Baxter International Inc. | Dialysis system with enhanced features |
US20120043279A1 (en) * | 2003-11-05 | 2012-02-23 | Baxter Healthcare S.A. | Systems and methods for priming sorbent-based hemodialysis |
US20120018378A1 (en) * | 2003-11-05 | 2012-01-26 | Baxter Healthcare S.A. | Renal failure therapy machines and methods including conductive and convective clearance |
US7332096B2 (en) * | 2003-12-19 | 2008-02-19 | Fenwal, Inc. | Blood filter assembly having multiple filtration regions |
US20120018377A1 (en) * | 2003-12-24 | 2012-01-26 | Chemica Technologies, Inc. | Dialysate regeneration system for portable human dialysis |
US8105260B2 (en) * | 2004-07-23 | 2012-01-31 | Gambro Lundia Ab | Machine and procedure for extracorporeal treatment of blood |
US7314208B1 (en) * | 2004-09-30 | 2008-01-01 | Sandia Corporation | Apparatus and method for selectively channeling a fluid |
US7873489B2 (en) * | 2005-03-04 | 2011-01-18 | B. Braun Medizintechnologie Gmbh | Dialysis machine with servicing indicator |
US7648476B2 (en) * | 2005-03-23 | 2010-01-19 | B. Braun Medizintechnologie Gmbh | Blood treatment apparatus with alarm device |
US20080041136A1 (en) * | 2006-01-25 | 2008-02-21 | Virbac Corporation | Ammonia detection device and related methods |
US20080041792A1 (en) * | 2006-08-18 | 2008-02-21 | Martin Crnkovich | Wetness sensor |
US8376978B2 (en) * | 2007-02-09 | 2013-02-19 | Baxter International Inc. | Optical access disconnection systems and methods |
US20090004053A1 (en) * | 2007-06-29 | 2009-01-01 | Kenley Rodney S | Devices, systems, and methods for cleaning, disinfecting, rinsing, and priming blood separation devices and associated fluid lines |
US20120022440A1 (en) * | 2007-07-05 | 2012-01-26 | Baxter Healthcare S.A. | Dialysis system having disposable cassette |
US20090008306A1 (en) * | 2007-07-05 | 2009-01-08 | Baxter International Inc. | Extracorporeal dialysis ready peritoneal dialysis machine |
US7874999B2 (en) * | 2007-09-24 | 2011-01-25 | Baxter International, Inc. | Detecting access disconnect using needle sleeve |
US8105487B2 (en) * | 2007-09-25 | 2012-01-31 | Fresenius Medical Care Holdings, Inc. | Manifolds for use in conducting dialysis |
US20120037550A1 (en) * | 2007-10-24 | 2012-02-16 | Baxter Healthcare S.A. | Hemodialysis system with cassette and pinch clamp |
US20120031826A1 (en) * | 2007-10-24 | 2012-02-09 | Baxter Healthcare S.A. | Hemodialysis system having clamping mechanism for peristaltic pumping |
US8114288B2 (en) * | 2007-11-29 | 2012-02-14 | Fresenlus Medical Care Holdings, Inc. | System and method for conducting hemodialysis and hemofiltration |
US20110000830A1 (en) * | 2008-02-07 | 2011-01-06 | Atsushi Ikeda | Hemodialysis apparatus |
US20110046533A1 (en) * | 2008-04-01 | 2011-02-24 | David Stefani | Apparatus and a method for monitoring a vascular access |
US20110028882A1 (en) * | 2008-04-04 | 2011-02-03 | Gambro Lundia Ab | medical apparatus |
US20110028881A1 (en) * | 2008-04-04 | 2011-02-03 | Gambro Lundia Ab | Medical apparatus comprising a machine for treatment of fluids |
US20120035534A1 (en) * | 2008-07-09 | 2012-02-09 | Baxter Healthcare S.A. | Dialysis system including wireless patient data and trending and alert generation |
US20120029937A1 (en) * | 2009-03-24 | 2012-02-02 | Debiotech S.A. | Dialysis device |
US20110009799A1 (en) * | 2009-05-15 | 2011-01-13 | Interface Biologics, Inc. | Antithrombogenic hollow fiber membranes and filters |
US20110041928A1 (en) * | 2009-08-22 | 2011-02-24 | Voelker Manfred | Supply device for dialysis apparatuses |
US20120029324A1 (en) * | 2010-04-16 | 2012-02-02 | Baxter Healthcare S.A. | Therapy prediction and optimization for renal failure blood therapy, especially home hemodialysis |
US20120010554A1 (en) * | 2010-07-08 | 2012-01-12 | Georges Vantard | Method and apparatus for controlling an extra-corporeal blood treatment in a medical device |
Cited By (138)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US10994067B2 (en) | 2002-01-04 | 2021-05-04 | Nxstage Medical, Inc. | Method and apparatus for machine error detection by combining multiple sensor inputs |
US9717840B2 (en) | 2002-01-04 | 2017-08-01 | Nxstage Medical, Inc. | Method and apparatus for machine error detection by combining multiple sensor inputs |
US10213540B2 (en) | 2002-01-04 | 2019-02-26 | Nxstage Medical, Inc. | Method and apparatus for machine error detection by combining multiple sensor inputs |
US8608658B2 (en) | 2002-01-04 | 2013-12-17 | Nxstage Medical, Inc. | Method and apparatus for machine error detection by combining multiple sensor inputs |
US8641615B2 (en) | 2002-01-04 | 2014-02-04 | Nxstage Medical, Inc. | Method and apparatus for machine error detection by combining multiple sensor inputs |
US11918729B2 (en) | 2006-11-09 | 2024-03-05 | Johnson & Johnson Surgical Vision, Inc. | Fluidics cassette for ocular surgical system |
US11337855B2 (en) | 2006-11-09 | 2022-05-24 | Johnson & Johnson Surgical Vision, Inc. | Holding tank devices, systems, and methods for surgical fluidics cassette |
US10441461B2 (en) | 2006-11-09 | 2019-10-15 | Johnson & Johnson Surgical Vision, Inc. | Critical alignment of fluidics cassettes |
US10959881B2 (en) | 2006-11-09 | 2021-03-30 | Johnson & Johnson Surgical Vision, Inc. | Fluidics cassette for ocular surgical system |
US11065153B2 (en) | 2006-11-09 | 2021-07-20 | Johnson & Johnson Surgical Vision, Inc. | Fluidics cassette for ocular surgical system |
US11058577B2 (en) | 2006-11-09 | 2021-07-13 | Johnson & Johnson Surgical Vision, Inc. | Fluidics cassette for ocular surgical system |
US10342701B2 (en) | 2007-08-13 | 2019-07-09 | Johnson & Johnson Surgical Vision, Inc. | Systems and methods for phacoemulsification with vacuum based pumps |
US10857281B2 (en) | 2007-09-13 | 2020-12-08 | Fresenius Medical Care Holdings, Inc. | Disposable kits adapted for use in a dialysis machine |
US9358331B2 (en) | 2007-09-13 | 2016-06-07 | Fresenius Medical Care Holdings, Inc. | Portable dialysis machine with improved reservoir heating system |
US11071811B2 (en) | 2007-09-13 | 2021-07-27 | Fresenius Medical Care Holdings, Inc. | Portable dialysis machine |
US11318248B2 (en) | 2007-09-13 | 2022-05-03 | Fresenius Medical Care Holdings, Inc. | Methods for heating a reservoir unit in a dialysis system |
US10258731B2 (en) | 2007-09-13 | 2019-04-16 | Fresenius Medical Care Holdings, Inc. | Manifold diaphragms |
US9517296B2 (en) | 2007-09-13 | 2016-12-13 | Fresenius Medical Care Holdings, Inc. | Portable dialysis machine |
US10383993B2 (en) | 2007-09-13 | 2019-08-20 | Fresenius Medical Care Holdings, Inc. | Pump shoe for use in a pumping system of a dialysis machine |
US9308307B2 (en) | 2007-09-13 | 2016-04-12 | Fresenius Medical Care Holdings, Inc. | Manifold diaphragms |
US10596310B2 (en) | 2007-09-13 | 2020-03-24 | Fresenius Medical Care Holdings, Inc. | Portable dialysis machine |
US11224841B2 (en) | 2007-09-25 | 2022-01-18 | Fresenius Medical Care Holdings, Inc. | Integrated disposable component system for use in dialysis systems |
US10022673B2 (en) | 2007-09-25 | 2018-07-17 | Fresenius Medical Care Holdings, Inc. | Manifolds for use in conducting dialysis |
US8858787B2 (en) | 2007-10-22 | 2014-10-14 | Baxter International Inc. | Dialysis system having non-invasive fluid velocity sensing |
US9724456B2 (en) | 2007-10-22 | 2017-08-08 | Baxter International Inc. | Dialysis system having non-invasive fluid velocity sensing |
US20090101550A1 (en) * | 2007-10-22 | 2009-04-23 | Baxter International Inc. | Dialysis system having non-invasive fluid velocity sensing |
US10034973B2 (en) | 2007-11-29 | 2018-07-31 | Fresenius Medical Care Holdings, Inc. | Disposable apparatus and kit for conducting dialysis |
US10758661B2 (en) | 2007-11-29 | 2020-09-01 | Fresenius Medical Care Holdings, Inc. | Disposable apparatus and kit for conducting dialysis |
US11439738B2 (en) | 2007-11-29 | 2022-09-13 | Fresenius Medical Care Holdings, Inc. | Methods and Systems for fluid balancing in a dialysis system |
US9415152B2 (en) | 2007-11-29 | 2016-08-16 | Fresenius Medical Care Holdings, Inc. | Disposable apparatus and kit for conducting dialysis |
US10758662B2 (en) | 2007-11-29 | 2020-09-01 | Fresenius Medical Care Holdings, Inc. | Priming system and method for dialysis systems |
US9759710B2 (en) | 2008-09-12 | 2017-09-12 | Fresenius Medical Care Holdings, Inc. | Modular reservoir assembly for a hemodialysis and hemofiltration system |
US10758868B2 (en) | 2008-10-30 | 2020-09-01 | Fresenius Medical Care Holdings, Inc. | Methods and systems for leak detection in a dialysis system |
US11169137B2 (en) | 2008-10-30 | 2021-11-09 | Fresenius Medical Care Holdings, Inc. | Modular reservoir assembly for a hemodialysis and hemofiltration system |
US10670577B2 (en) | 2008-10-30 | 2020-06-02 | Fresenius Medical Care Holdings, Inc. | Modular reservoir assembly for a hemodialysis and hemofiltration system |
US10905588B2 (en) | 2008-11-07 | 2021-02-02 | Johnson & Johnson Surgical Vision, Inc. | Automatically pulsing different aspiration levels to an ocular probe |
US10478534B2 (en) | 2008-11-07 | 2019-11-19 | Johnson & Johnson Surgical Vision, Inc. | Automatically switching different aspiration levels and/or pumps to an ocular probe |
US10238778B2 (en) | 2008-11-07 | 2019-03-26 | Johnson & Johnson Surgical Vision, Inc. | Automatically switching different aspiration levels and/or pumps to an ocular probe |
US10251983B2 (en) | 2008-11-07 | 2019-04-09 | Johnson & Johnson Surgical Vision, Inc. | Automatically switching different aspiration levels and/or pumps to an ocular probe |
US11266526B2 (en) | 2008-11-07 | 2022-03-08 | Johnson & Johnson Surgical Vision, Inc. | Automatically pulsing different aspiration levels to an ocular probe |
US10668192B2 (en) | 2008-11-07 | 2020-06-02 | Johnson & Johnson Surgical Vision, Inc. | Automatically switching different aspiration levels and/or pumps to an ocular probe |
US10813790B2 (en) | 2008-11-07 | 2020-10-27 | Johnson & Johnson Surgical Vision, Inc. | Automatically pulsing different aspiration levels to an ocular probe |
US10265443B2 (en) | 2008-11-07 | 2019-04-23 | Johnson & Johnson Surgical Vision, Inc. | Surgical cassette apparatus |
US10993839B2 (en) | 2008-11-07 | 2021-05-04 | Johnson & Johnson Surgical Vision, Inc. | Automatically pulsing different aspiration levels to an ocular probe |
US10219940B2 (en) | 2008-11-07 | 2019-03-05 | Johnson & Johnson Surgical Vision, Inc. | Automatically pulsing different aspiration levels to an ocular probe |
US11369729B2 (en) | 2008-11-07 | 2022-06-28 | Johnson & Johnson Surgical Vision, Inc. | Automatically switching different aspiration levels and/or pumps to an ocular probe |
US11369728B2 (en) | 2008-11-07 | 2022-06-28 | Johnson & Johnson Surgical Vision, Inc. | Automatically switching different aspiration levels and/or pumps to an ocular probe |
US11364145B2 (en) | 2008-11-07 | 2022-06-21 | Johnson & Johnson Surgical Vision, Inc. | Automatically pulsing different aspiration levels to an ocular probe |
US10197180B2 (en) | 2009-01-12 | 2019-02-05 | Fresenius Medical Care Holdings, Inc. | Valve system |
US9360129B2 (en) | 2009-01-12 | 2016-06-07 | Fresenius Medical Care Holdings, Inc. | Valve system |
US10808861B2 (en) | 2009-01-12 | 2020-10-20 | Fresenius Medical Care Holdings, Inc. | Valve system |
US9877865B2 (en) | 2009-03-31 | 2018-01-30 | Abbott Medical Optics Inc. | Cassette capture mechanism |
US20120181296A1 (en) * | 2009-09-29 | 2012-07-19 | Andreas Syfonios | Housing with closure flap |
US9289543B2 (en) * | 2009-09-29 | 2016-03-22 | Fresenius Medical Care Deutschland Gmbh | Housing with closure flap |
US9020827B2 (en) * | 2009-10-16 | 2015-04-28 | Baxter International Inc. | Peritoneal dialysis optimized using a patient hand-held scanning device |
US10449284B2 (en) | 2009-10-16 | 2019-10-22 | Baxter Interntional Inc. | Optimizing peritoneal dialysis using a patient hand-held scanning device |
US20110093294A1 (en) * | 2009-10-16 | 2011-04-21 | Baxter International Inc. | Peritoneal dialysis optimized using a patient hand-held scanning device |
US11607479B2 (en) | 2009-10-16 | 2023-03-21 | Baxter International Inc. | Optimizing peritoneal dialysis using a patient hand-held scanning device |
US11058809B2 (en) | 2009-10-16 | 2021-07-13 | Baxter International Inc. | Optimizing peritoneal dialysis using a patient hand-held scanning device |
US20170151383A1 (en) * | 2011-01-18 | 2017-06-01 | Fresenius Medical Care Deutschland Gmbh | Method for querying a specification feature of a medical technical functional means, a medical technical functional means, a medical device and a control unit |
CN107050549A (en) * | 2011-01-18 | 2017-08-18 | 弗雷塞尼斯医疗保健德国有限责任公司 | Method, functional medicine device, Medical Devices and control device for the specification features of query function medical apparatus |
US9550021B2 (en) * | 2011-01-18 | 2017-01-24 | Fresenius Medical Care Deutschland Gmbh | Method for querying a specification feature of a medical technical functional means, a medical technical functional means, a medical device and a control unit |
US10420875B2 (en) * | 2011-01-18 | 2019-09-24 | Fresenius Medical Care Deutschland Gmbh | Method for querying a specification feature of a medical technical functional means, a medical technical functional means, a medical device and a control unit |
US20120181331A1 (en) * | 2011-01-18 | 2012-07-19 | Fresenius Medical Care Deutschland Gmbh | Method for querying a specification feature of a medical technical functional means, a medical technical functional means, a medical device and a control unit |
US20120197185A1 (en) * | 2011-02-02 | 2012-08-02 | Kai Tao | Electromechanical system for IV control |
CN103476486A (en) * | 2011-02-08 | 2013-12-25 | 弗雷塞尼斯医疗保健控股公司 | Portable dialysis machine |
CN107441575A (en) * | 2011-02-08 | 2017-12-08 | 弗雷塞尼斯医疗保健控股公司 | Portable dialysis machine |
US9599599B2 (en) | 2011-04-06 | 2017-03-21 | Fresenius Medical Care Holdings, Inc. | Measuring chemical properties of a sample fluid in dialysis systems |
US8945936B2 (en) * | 2011-04-06 | 2015-02-03 | Fresenius Medical Care Holdings, Inc. | Measuring chemical properties of a sample fluid in dialysis systems |
US10722636B2 (en) | 2011-08-02 | 2020-07-28 | Medtronic, Inc. | Hemodialysis system having a flow path with a controlled compliant volume |
US10695481B2 (en) | 2011-08-02 | 2020-06-30 | Medtronic, Inc. | Hemodialysis system having a flow path with a controlled compliant volume |
US10857277B2 (en) | 2011-08-16 | 2020-12-08 | Medtronic, Inc. | Modular hemodialysis system |
US20130105425A1 (en) * | 2011-10-27 | 2013-05-02 | Daniel Rodriguez | Portable Apparatus for Life Support Equipment |
US10980668B2 (en) | 2012-03-17 | 2021-04-20 | Johnson & Johnson Surgical Vision, Inc. | Surgical cassette |
US10888456B2 (en) | 2012-03-17 | 2021-01-12 | Johnson & Johnson Surgical Vision, Inc. | Surgical cassette |
US10857029B2 (en) | 2012-03-17 | 2020-12-08 | Johnson & Johnson Surgical Vision, Inc. | Valve system of surgical cassette manifold, system, and methods thereof |
US10583040B2 (en) * | 2012-03-17 | 2020-03-10 | Johnson & Johnson Surgical Vision, Inc. | Device, system and method for assessing attitude and alignment of a surgical cassette |
US11872159B2 (en) | 2012-03-17 | 2024-01-16 | Johnson & Johnson Surgical Vision, Inc. | Pre-alignment surgical cassette interface |
US9895262B2 (en) | 2012-03-17 | 2018-02-20 | Abbott Medical Optics Inc. | Device, system and method for assessing attitude and alignment of a surgical cassette |
US10265217B2 (en) | 2012-03-17 | 2019-04-23 | Johnson & Johnson Surgical Vision, Inc. | Pre-alignment surgical cassette interface |
US10219938B2 (en) | 2012-03-17 | 2019-03-05 | Johnson & Johnson Surgical Vision, Inc. | Surgical cassette manifold, system, and methods thereof |
US11154422B2 (en) | 2012-03-17 | 2021-10-26 | Johnson & Johnson Surgical Vision, Inc. | Surgical cassette manifold, system, and methods thereof |
US10905816B2 (en) | 2012-12-10 | 2021-02-02 | Medtronic, Inc. | Sodium management system for hemodialysis |
US11525798B2 (en) | 2012-12-21 | 2022-12-13 | Fresenius Medical Care Holdings, Inc. | Method and system of monitoring electrolyte levels and composition using capacitance or induction |
WO2014105267A1 (en) * | 2012-12-24 | 2014-07-03 | Fresenius Medical Care Holdings, Inc. | Load suspension and weighing system for a dialysis machine reservoir |
US11187572B2 (en) | 2012-12-24 | 2021-11-30 | Fresenius Medical Care Holdings, Inc. | Dialysis systems with a suspended reservoir |
US9157786B2 (en) | 2012-12-24 | 2015-10-13 | Fresenius Medical Care Holdings, Inc. | Load suspension and weighing system for a dialysis machine reservoir |
US10539450B2 (en) | 2012-12-24 | 2020-01-21 | Fresenius Medical Care Holdings, Inc. | Load suspension and weighing system for a dialysis machine reservoir |
EP2950840A4 (en) * | 2013-02-01 | 2016-09-14 | Medtronic Inc | Modular fluid therapy system having jumpered flow paths and systems and methods for cleaning and disinfection |
US11786645B2 (en) | 2013-02-01 | 2023-10-17 | Mozarc Medical Us Llc | Fluid circuit for delivery of renal replacement therapies |
US10532141B2 (en) | 2013-02-01 | 2020-01-14 | Medtronic, Inc. | Systems and methods for multifunctional volumetric fluid control |
US10010663B2 (en) | 2013-02-01 | 2018-07-03 | Medtronic, Inc. | Fluid circuit for delivery of renal replacement therapies |
US10850016B2 (en) | 2013-02-01 | 2020-12-01 | Medtronic, Inc. | Modular fluid therapy system having jumpered flow paths and systems and methods for cleaning and disinfection |
US10561776B2 (en) | 2013-02-01 | 2020-02-18 | Medtronic, Inc. | Fluid circuit for delivery of renal replacement therapies |
US9872949B2 (en) | 2013-02-01 | 2018-01-23 | Medtronic, Inc. | Systems and methods for multifunctional volumetric fluid control |
US10543052B2 (en) | 2013-02-01 | 2020-01-28 | Medtronic, Inc. | Portable dialysis cabinet |
DE102013102281A1 (en) * | 2013-03-07 | 2014-09-11 | B. Braun Avitum Ag | Dialysis machine with self-supporting machine housing |
US20140252926A1 (en) * | 2013-03-07 | 2014-09-11 | B. Braun Avitum Ag | Dialysis machine with self-supporting machine housing |
US11701459B2 (en) | 2013-03-14 | 2023-07-18 | Fresenius Medical Care Holdings, Inc. | Universal portable artificial kidney for hemodialysis and peritoneal dialysis |
US11246972B2 (en) | 2013-03-14 | 2022-02-15 | Fresenius Medical Care Holdings, Inc. | Universal portable machine for online hemodiafiltration using regenerated dialysate |
US10549023B2 (en) | 2013-03-14 | 2020-02-04 | Fresenius Medical Care Holdings, Inc. | Universal portable artificial kidney for hemodialysis and peritoneal dialysis |
EP3777914A1 (en) | 2013-03-14 | 2021-02-17 | Fresenius Medical Care Holdings, Inc. | Universal portable machine for online hemodiafiltration using regenerated dialysate |
WO2014151322A1 (en) | 2013-03-14 | 2014-09-25 | Fresenius Medical Care Holdings, Inc. | Universal portable machine for online hemodiafiltration using regenerated dialysate |
US10792414B2 (en) | 2013-03-14 | 2020-10-06 | Fresenius Medical Care Holdings, Inc. | Universal portable machine for online hemodiafiltration using regenerated dialysate |
US9433720B2 (en) | 2013-03-14 | 2016-09-06 | Fresenius Medical Care Holdings, Inc. | Universal portable artificial kidney for hemodialysis and peritoneal dialysis |
US10258727B2 (en) * | 2013-08-23 | 2019-04-16 | Fresenius Medical Care Deutschland Gmbh | Disposable articles for dialysis treatment, dialyzer and a water preparation plant for dialysate |
US20160199559A1 (en) * | 2013-08-23 | 2016-07-14 | Fresenius Medical Care Deutschland Gmbh | Disposable articles for dialysis treatment, dialyzer and a water preparation plant for dialysate |
US9354640B2 (en) | 2013-11-11 | 2016-05-31 | Fresenius Medical Care Holdings, Inc. | Smart actuator for valve |
US10019020B2 (en) | 2013-11-11 | 2018-07-10 | Fresenius Medical Care Holdings, Inc. | Smart actuator for valve |
US10817004B2 (en) | 2013-11-11 | 2020-10-27 | Fresenius Medical Care Holdings, Inc. | Valve system with a pressure sensing displacement member |
WO2016039837A1 (en) * | 2014-09-12 | 2016-03-17 | Easydial, Inc. | Portable hemodialysis machine and disposable cartridge with dialysis reservoir level sensor |
US10874787B2 (en) | 2014-12-10 | 2020-12-29 | Medtronic, Inc. | Degassing system for dialysis |
US10195327B2 (en) | 2014-12-10 | 2019-02-05 | Medtronic, Inc. | Sensing and storage system for fluid balance |
US9895479B2 (en) | 2014-12-10 | 2018-02-20 | Medtronic, Inc. | Water management system for use in dialysis |
US9713665B2 (en) | 2014-12-10 | 2017-07-25 | Medtronic, Inc. | Degassing system for dialysis |
US10420872B2 (en) | 2014-12-10 | 2019-09-24 | Medtronic, Inc. | Degassing system for dialysis |
US10098993B2 (en) | 2014-12-10 | 2018-10-16 | Medtronic, Inc. | Sensing and storage system for fluid balance |
US11224682B2 (en) * | 2015-08-11 | 2022-01-18 | Fresenius Medical Care Deutschland Gmbh | Peritoneal dialysis machine |
US20180236155A1 (en) * | 2015-08-11 | 2018-08-23 | Fresenius Medical Care Deutschland Gmbh | Peritoneal dialysis machine |
US10786616B2 (en) | 2015-12-17 | 2020-09-29 | Fresnius Medical Care Holdings, Inc. | System and method for controlling venous air recovery in a portable dialysis system |
US10987460B2 (en) | 2016-03-08 | 2021-04-27 | Fresenius Medical Care Holdings, Inc. | Methods and systems of generating rapidly varying pressure amplitudes in fluidic circuits in a dialysis treatment system |
US10850017B2 (en) | 2016-03-08 | 2020-12-01 | Fresenius Medical Care Holdings, Inc. | Methods and systems for detecting an occlusion in a blood circuit of a dialysis system |
US10195326B2 (en) | 2016-03-08 | 2019-02-05 | Fresenius Medical Care Holdings, Inc. | Methods and systems for detecting an occlusion in a blood circuit of a dialysis system |
US10561778B2 (en) | 2017-03-02 | 2020-02-18 | Fresenius Medical Care Holdings, Inc. | Split reservoir bags and method of using split reservoir bags to improve the heating and generation of dialysate |
WO2018187172A1 (en) * | 2017-04-07 | 2018-10-11 | Fresenius Medical Care Holdings, Inc. | Methods and systems for measuring and heating dialysate |
US11110214B2 (en) | 2017-04-07 | 2021-09-07 | Fresenius Medical Care Holdings, Inc. | Methods and systems for measuring and heating dialysate |
US11266773B2 (en) * | 2017-07-11 | 2022-03-08 | Fresenius Medical Care Holdings, Inc. | Fluid leak detection in a dialysis machine |
US20190015577A1 (en) * | 2017-07-11 | 2019-01-17 | Fresenius Medical Care Holdings, Inc. | Fluid leak detection in a dialysis machine |
CN110869068A (en) * | 2017-07-11 | 2020-03-06 | 费森尤斯医疗保健控股公司 | Fluid leak detection in dialysis machines |
US10888649B2 (en) | 2017-07-11 | 2021-01-12 | Fresenius Medical Care Holdings, Inc. | Fluid leak detection in a dialysis machine |
AU2018301784B2 (en) * | 2017-07-11 | 2020-05-07 | Fresenius Medical Care Holdings, Inc. | Fluid leak detection in a dialysis machine |
US10682455B2 (en) * | 2017-07-11 | 2020-06-16 | Fresenius Medical Care Holdings, Inc. | Fluid leak detection in a dialysis machine |
US11278654B2 (en) | 2017-12-07 | 2022-03-22 | Medtronic, Inc. | Pneumatic manifold for a dialysis system |
US10533308B2 (en) | 2017-12-18 | 2020-01-14 | George Taweh | Dialysis wall box apparatus and wall chase system |
US11033667B2 (en) | 2018-02-02 | 2021-06-15 | Medtronic, Inc. | Sorbent manifold for a dialysis system |
US11110215B2 (en) | 2018-02-23 | 2021-09-07 | Medtronic, Inc. | Degasser and vent manifolds for dialysis |
US11273246B2 (en) | 2019-11-12 | 2022-03-15 | Fresenius Mesical Care Holdings, Inc. | Piston assembly including leak detection in a dialysis machine |
WO2023069886A1 (en) * | 2021-10-21 | 2023-04-27 | Siemens Healthcare Diagnostics Inc. | Fluidic tubing assembly for blood analyzer |
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