US20100135824A1 - Process for Peristaltic Pump Control - Google Patents

Process for Peristaltic Pump Control Download PDF

Info

Publication number
US20100135824A1
US20100135824A1 US12/611,293 US61129309A US2010135824A1 US 20100135824 A1 US20100135824 A1 US 20100135824A1 US 61129309 A US61129309 A US 61129309A US 2010135824 A1 US2010135824 A1 US 2010135824A1
Authority
US
United States
Prior art keywords
medium
undulation
flow rate
squeezing elements
tube
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
US12/611,293
Other languages
English (en)
Inventor
Simon Ickinger
Arnold Bartel
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Roche Diagnostics Operations Inc
Original Assignee
Roche Diagnostics Operations Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roche Diagnostics Operations Inc filed Critical Roche Diagnostics Operations Inc
Assigned to ROCHE DIAGNOSTICS GRAZ GMBH reassignment ROCHE DIAGNOSTICS GRAZ GMBH ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors: BARTEL, ARNOLD, ICKINGER, SIMON
Assigned to ROCHE DIAGNOTICS OPERATIONS, INC. reassignment ROCHE DIAGNOTICS OPERATIONS, INC. ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors: ROCHE DIAGNOTICS GRAZ GMBH
Publication of US20100135824A1 publication Critical patent/US20100135824A1/en
Abandoned legal-status Critical Current

Links

Images

Classifications

    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
    • F04B—POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
    • F04B43/00—Machines, pumps, or pumping installations having flexible working members
    • F04B43/0009—Special features
    • F04B43/0081—Special features systems, control, safety measures
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
    • F04B—POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
    • F04B43/00—Machines, pumps, or pumping installations having flexible working members
    • F04B43/12—Machines, pumps, or pumping installations having flexible working members having peristaltic action
    • F04B43/1253—Machines, pumps, or pumping installations having flexible working members having peristaltic action by using two or more rollers as squeezing elements, the rollers moving on an arc of a circle during squeezing
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
    • F04B—POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
    • F04B49/00—Control, e.g. of pump delivery, or pump pressure of, or safety measures for, machines, pumps, or pumping installations, not otherwise provided for, or of interest apart from, groups F04B1/00 - F04B47/00
    • F04B49/06—Control using electricity
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
    • F04B—POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
    • F04B2203/00—Motor parameters
    • F04B2203/02—Motor parameters of rotating electric motors
    • F04B2203/0209—Rotational speed
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
    • F04B—POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
    • F04B2205/00—Fluid parameters
    • F04B2205/05—Pressure after the pump outlet
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
    • F04B—POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
    • F04B2205/00—Fluid parameters
    • F04B2205/09—Flow through the pump
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
    • F04B—POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
    • F04B2205/00—Fluid parameters
    • F04B2205/13—Pressure pulsations after the pump

Definitions

  • the present invention is directed to peristaltic pumps and, in particular, to a process for peristaltic pump control.
  • Peristaltic pumps are displacement pumps in which the medium to be conveyed is guided through a tube which, in most cases, is U-shaped, but may also be linear or arranged along largely any path.
  • Said tube is supported in the body of the pump and is pinched successively by squeezing elements such as rolls or sliding blocks, which are moved by an actuator.
  • Said actuator is usually designed as a rotor. The rotation of the rotor moves the pinched point generated by the squeezing elements along the tube and thus pushes forward a volume of the medium to be conveyed in the tube, which volume is located ahead of the pinched point. Simultaneously, a negative suction pressure is generated at the tube inlet.
  • the actuators are designed as linear drives, or a plurality of squeezing elements are consecutively arranged along the tube—in the manner of a piano keyboard—and are each pressed in succession against the tube by a separate actuator so that a kind of progressive motion develops.
  • the essential advantages of peristaltic pumps are a careful transport of sensitive materials to be conveyed, a completely closed system, absence of valves, a possibility of conveying media with solid particles and precise dosability of outputs. Because of those properties, peristaltic pumps are frequently used in laboratory equipment, e.g., in blood analysis devices, in which peristaltic pumps are used for the transport of blood samples in the device or the washing process, etc.
  • peristaltic pumps have the disadvantage that variable delivery rates occur because of varying tube properties and wear of the tube.
  • an undulation of the flow rate of the medium is produced in the tube by the mechanical engagement of the rolls with the tube and the displacement of the medium to be conveyed which thereby is caused, as can be seen in the chart of FIG. 2 .
  • the undulation constitutes a deviation from the average flow rate and temporarily brings about a higher or lower rate of flow depending on the position of the engaging rolls.
  • the chart of FIG. 2 illustrates the temporal course of the flow rates v of the medium to be conveyed in ⁇ l/min for a peristaltic pump having two different tubes of the same type, but of different ages and different batch numbers, respectively.
  • peristaltic pump is provided with a determination of the position of the rolls.
  • This may be, for example, an inductive or optical pulse generator on a roll. As soon as the roll equipped with the pulse generator passes a measuring point, a signal is emitted.
  • a stepping motor drives the rotor of the pump, a determination of position can be performed by the internal control of the stepping motor.
  • the undulation of the flow rate of the peristaltic pump occurs periodically depending on the position of the rolls, said undulation is smoothed, i.e., reduced, by means of a motor-control in that the motor-control controls the motor driving the rotor by a change in the rotor's angular velocity which counteracts the undulation of the flow rate, depending on the position of the rolls.
  • the motor-control has to be adjusted such that it levels out a minimum undulation (in FIG. 2 , this would be, for example, flow rate curve M 2 with the smaller amplitude).
  • the drawback is that a residual undulation remains for all pump configurations except for that with the minimum undulation.
  • a proportion of the sample volume is required as a “tolerance volume”, which is necessary for levelling out the undulation of the flow rate.
  • the sample is positioned on a sensor which is for the respective determination of analytes and is arranged in the flow path of the sample, with the control of the sample positioning occurring on the basis of a defined constant flow rate.
  • the actual flow rate of the sample is not constant, but exhibits an undulation due to the properties of the peristaltic pump, it may happen that the sample stops ahead of or after the sensor, depending on the current flow rate. In order to avoid this uncertainty in the positioning of the sample, an enlarged sample volume having the above-mentioned tolerance-volume proportion must be provided.
  • the present invention provides a solution for the illustrated problems of the prior art.
  • the undulation of the delivery rate of peristaltic pumps is reduced by the present invention, and a peristaltic pump control is provided which enables continuous calibration of a peristaltic pump during operation with regard to the flow rate and the undulation thereof.
  • the undulation of such peristaltic pumps is reduced which do not constitute a closed unit, but in which the tube is a replacement part or a consumption material which is replaced at relatively short intervals.
  • a process for controlling a peristaltic pump comprises measuring over time a fluidic parameter representative for the flow rate of the medium through the tube, determining the relative undulation of the flow rate of the medium from the measured temporal course of the fluidic parameter, and smoothing the undulation by adjusting the progression speed of the squeezing elements on the basis of the determined undulation of the flow rate.
  • FIG. 1 shows the schematic structure of a peristaltic pump
  • FIG. 2 shows a diagram of two temporal courses of flow rates of a medium conveyed in a peristaltic pump according to the prior art before and after the replacement of the tube;
  • FIG. 3 shows a block diagram of an arrangement of a peristaltic pump having a pump control according to the invention and means for detecting fluidic parameters according to the present invention
  • FIG. 4 shows a specific arrangement for detecting fluidic parameters according to the present invention.
  • every measurand suitable for measuring or detecting changes in the flow rate through the tube of the peristaltic pump is provided as a fluidic parameter.
  • the solution according to the invention is based on the principle that the undulation of the flow rate can be leveled out or at least reduced by adjusting the progression speed of the squeezing elements of the peristaltic pump, depending on the current position of the squeezing elements.
  • the invention additionally takes into account that the undulation of the flow rate may change if the tube of the peristaltic pump is replaced and/or due to the aging of the tube.
  • the invention envisages that the variation of the progression speed of the squeezing elements of the peristaltic pump, which is necessary for smoothing the undulation of the flow rate, is adapted to the current tube properties by a recurring calibration during running operation and an appropriate adjustment of the control of the rotational speed of the rotor.
  • the invention is suitable for use in peristaltic pumps which do not form an inseparable unit, but in which the tube has to be replaced again and again as a consumption material.
  • the invention is suitable for use in classical, simple peristaltic pumps with a constant speed of the squeezing elements, which has been preset in the factory, and also in peristaltic pumps which are calibrated in the factory to particular tube properties by presetting a periodical variation of the progression speed which depends on the position of the squeezing elements.
  • the undulation is smoothed by adjusting the preset periodical variation of the progression speed of the squeezing elements on the basis of the relative undulation of the flow rate which has been determined.
  • the adjustment of the periodical variation of the progression speed of the squeezing elements comprises calculating a calibration factor from the determined undulation of the flow rate of the medium and readjusting the periodical variation of the progression speed of the squeezing elements by the calibration factor.
  • the calibration factor (or the determined undulation of the flow rate as a quantity associated therewith) during running operation to find out if it lies within predetermined limits and to conduct a recalculation of the calibration factor if those limits are exceeded, which will result in an adaptation of the periodical variation of the progression speed of the squeezing elements.
  • the invention is suitable for use in all types of peristaltic pumps, for example, the initially mentioned types, in which the tube is linear or arranged along any desired predetermined path.
  • the squeezing elements may be arranged, for example, along the tube in the form of a “piano keyboard” while being movable individually by actuators or may be moved jointly by an actuator such as a linear drive or by a band driven by a conveyor belt.
  • the actuator is a rotor driven by a motor, from which rotor the squeezing elements are moved in a circular motion along the tube, whereby the position of the squeezing elements is detected during the rotation of the rotor and the progression speed of the squeezing elements is adjusted by controlling the angular velocity of the rotor.
  • the flow rate of the medium is measured as a fluidic parameter by detecting the time period required by medium packages or by the front and end of the medium or by the front and end of medium packages for passing with a constant measuring volume through a measuring section located in the flow path of the peristaltic pump.
  • the positions of the squeezing elements are detected and allocated to the time periods, resulting in a curve of the relative undulation of the flow rate.
  • the medium packages are typically generated by introducing air bubbles into the medium flow, with the medium flow originating either from a sample medium or a calibration liquid, for example, a calibration liquid, a quality control liquid or a washing liquid of a blood analysis device.
  • a calibration liquid for example, a calibration liquid, a quality control liquid or a washing liquid of a blood analysis device.
  • the measuring volume of the measuring section and the size of the medium packages are chosen such that the period of the undulation of the flow rate which corresponds to the distance between adjacent squeezing elements and the progression speed of the squeezing elements, in particular to the angular velocity of the rotor, is a multiple of the time period required by the medium packages for flowing through the measuring section.
  • a precise and quick measurement of the duration of the passing of the medium packages through the measuring section is typically achieved by using optical sensors.
  • a defined measuring section and a time measurement other fluidic parameters can also be used for measuring the undulation, namely in particular the pressure of the medium which is detected by a pressure sensor, or the temperature of the medium which is detected by a temperature sensor, or the flow rate of the medium itself which is detected by a flowmeter.
  • the medium can also be guided into a weighing cell, wherein the relative weight change of said weighing cell is the fluidic parameter.
  • the electrical conductivity of the medium can be measured as a fluidic parameter by a conductivity sensor.
  • measurands which are suitable for measuring or detecting changes in the flow rate through the tube of the peristaltic pump can be used as possible fluidic parameters.
  • indirect measurands can also be used, which in turn depend on further measurands which respond in a characteristic way to changes in the flow rate through the tube of the peristaltic pump.
  • a peristaltic pump it is envisaged to perform the process for controlling a peristaltic pump after every exchange of the tube in order to adequately consider the modifications of flow parameters, etc., during the operation of the pump, which may have been caused by the replacement of the tube.
  • This aspect of the invention is important especially for peristaltic pumps in which the tube is designed as a replacement part or is integrated in such a part.
  • the peristaltic pump 1 comprises a rotor 3 which is driven by a motor 2 toward a rotation in the direction of arrow r.
  • the rotor 3 On its circumference, the rotor 3 comprises squeezing elements 4 which are spaced apart at equal distances and, in this embodiment, are designed as rolls. Alternatively, the squeezing elements 4 might be designed as sliding elements.
  • the rotor 3 is embraced by a tube 5 at an angle of approx. 180°, which, on its outside, is supported on a body structure 6 .
  • the squeezing elements 4 With a rotation of the rotor 3 , the squeezing elements 4 successively get into and out of a squeezing engagement with the tube 5 , whereby a negative pressure is produced at the inlet 5 a of the tube 5 , which negative pressure sucks a medium 7 to be conveyed through the peristaltic pump, such as, e.g., a blood sample or a rinsing liquid, into the tube 5 , transporting it through the tube 5 as far as to the pump outlet 5 b .
  • the corrugated course of the flow rate v of the medium 7 as illustrated in the chart of FIG. 2 appears, wherein, in the chart of FIG.
  • the undulation w can be determined as the peak-peak-difference of the amplitude of each period p.
  • the period p of the undulation w in turn results from the angular velocity r of the rotor 3 and the distance between adjacent squeezing elements 4 .
  • a new period p starts which lasts until the next squeezing element 4 engages the tube 5 .
  • a position sensor 8 may be provided. If the motor 2 is designed as a stepping motor, it is also possible to detect the position of the squeezing elements 4 from the step sequence of the motor.
  • the peristaltic pump 1 is known from the prior art.
  • it would display a fairly smooth delivery behaviour only for a tube 5 with precisely defined properties, even if the known variation of the angular velocity r of the rotor is provided.
  • the delivery behaviour would in practice exhibit the known undulations of the flow rate of the medium.
  • the undulation of the flow rate of a medium 7 conveyed through the tube 5 can be kept permanently at a minimum.
  • FIG. 3 shows a block diagram of an arrangement of the peristaltic pump 1 of FIG. 1 comprising a pump control 12 according to the invention and measuring equipment 10 for detecting fluidic parameters according to the present invention.
  • the peristaltic pump 1 is equipped with a position sensor 8 for detecting the exact position of the squeezing elements 4 of the rotor 3 .
  • the pump control 12 is designed for periodically varying the angular velocity of the rotor 3 according to a predetermined course, depending on the position of the squeezing elements 4 , so that a base reduction of the undulation of the flow rate v of a medium 7 conveyed through the tube 5 is achieved.
  • the predetermined course of the periodical variation of the angular velocity of the rotor 3 can be stored, for example, in a table in a memory of the pump control 12 .
  • Said table is created, for example, during the assembly of the pump 1 by detecting the course of the flow rate of the medium through the tube 5 with a uniform rotation of the rotor 3 and calculating a compensating curve which counteracts the undulation of the flow rate and is stored in the memory of the control 12 in the form of said table.
  • the invention provides calibration means 11 which are designed, e.g., as a microprocessor and recalibrate the pump control 12 at certain time intervals.
  • the time intervals of the calibration can either be event-driven, e.g., every time the tube 5 is replaced, or can be determined in a time-controlled manner on the basis of predetermined intervals.
  • the calibration means 11 detect a fluidic parameter FP which is representative for the flow rate v of the medium and is measured by means of the measuring equipment 10 .
  • the calibration means 11 determine the undulation of the flow rate of the medium from the measured fluidic parameter FP (cf., chart of FIG. 2 ) and readjust the periodical variation of the angular velocity r of the rotor 3 , which has been caused by the pump control 12 , on the basis of the determined undulation of the flow rate in such a way that it will counteract the undulation of the flow rate, thus reducing it. More precisely, the basic course of the variation of the angular velocity of the rotor is maintained due to this change in the pump control 12 , but the absolute values and the amplitude, respectively, are adjusted.
  • this is achieved by multiplying the prestored course of the variation of the angular velocity in the pump control 12 by a calibration factor KF which is calculated by the calibration means 11 depending on the detected undulation w of the flow rate v and is transmitted to the pump control 12 .
  • KF which is calculated by the calibration means 11 depending on the detected undulation w of the flow rate v and is transmitted to the pump control 12 .
  • Said calibration process may be repeated iteratively until the desired smoothing of the undulation is achieved.
  • the course of the variation of the angular velocity of the rotor 3 resulting therefrom is maintained until a new calibration is performed.
  • a fluid switch 13 can be arranged upstream of the peristaltic pump 1 , which, during normal operation, supplies the pump with the sample medium 17 as a medium 7 to be conveyed and, for the calibration, delivers a calibration liquid 14 , which, for example, is a rinsing liquid.
  • a valve 16 is provided in the path of the calibration liquid 14 , by means of which valve air 15 can be introduced in order to generate in this way individual medium packages 14 from the flow of calibration liquid 14 , as will be explained in further detail below.
  • a collection container 18 for the medium 7 is provided downstream of the means 10 for detecting a fluidic parameter.
  • the means 10 for detecting a fluidic parameter FP may be based on various sensory principles, in particular on physical principles.
  • the fluidic parameter FP is the pressure of the medium 7 , with the detection means 10 being designed as a pressure sensor.
  • the fluidic parameter FP is the temperature of the medium 7 , with the detection means 10 being designed as a temperature sensor.
  • the fluidic parameter FP consists in the relative weight changes of a weighing cell into which the medium 7 is introduced.
  • the weight of the collection container 18 is constantly determined, with the detection means 10 being designed as a balance.
  • the fluidic parameter is the flow rate of the medium, with the detection means 10 being designed as a flowmeter.
  • the fluidic parameter FP is the electrical conductivity of the medium 7 , with the detection means 10 being designed as a conductivity sensor.
  • the measuring section MS is located in the fluidic path of the peristaltic pump, e.g., in the tube 5 or in a conduit located downstream thereof.
  • the measuring section MS has a constant volume, which, however, is possibly unknown due to component tolerances.
  • Said measuring section MS is delimited by two optical sensors S 1 , S 2 , which are able to identify medium packages 14 a and their beginnings and ends, respectively, during running operation. Those medium packages are generated by switching the fluid switch 13 (see FIG. 3 ) to the supply of calibration liquid 14 and introducing air 15 in a temporal sequence through the valve 16 into the calibration liquid 14 .
  • the medium packages 14 a have different volumes and/or different distances between each other.
  • the residence time of the medium packages 14 in the measuring section is measured and plotted into a table or chart depending on the position of the squeezing elements.
  • the process is repeated with several medium packages 14 a , which results in a table or curve, respectively, of the relative undulation depending on the position of the squeezing elements.
  • the length of the measuring section MS is to be chosen such that the time required by each medium package 14 a for passing through the measuring section MS is only a fraction, e.g., less than a fifth of the period duration p of the undulation w of the peristaltic pump 1 . In this way, it can be achieved that not only a mean value of the flow rate v, but an individual value is determined within a period p of the undulation w.
  • the control of the fluid switch 13 and of the valve 16 is effected via the calibration means 11 which are supplied with the duration of the passing of the medium packages 14 a through the measuring section MS as a fluidic parameter FP and simultaneously are supplied with the exact positions of the squeezing elements 4 by the position sensor 8 and are thus able to create the above-mentioned table or curve, respectively, of the relative undulation.
  • a calibration factor KF is calculated by means of the table and supplied to the pump control 12 which changes the absolute values and the amplitude, respectively, of the periodically varying angular velocity of the rotor on the basis of the determined calibration factor KF.
  • the control 12 of the peristaltic pump 1 can thus be calibrated with every tube exchange and for every operating state, respectively, or at regular intervals.
  • the fluid switch 13 is switched into the position in which the sample medium 17 is supplied to the peristaltic pump 1 .
  • the term “substantially” is utilized herein to represent the inherent degree of uncertainty that may be attributed to any quantitative comparison, value, measurement, or other representation.
  • the term “substantially” is also utilized herein to represent the degree by which a quantitative representation may vary from a stated reference without resulting in a change in the basic function of the subject matter at issue.

Landscapes

  • Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • General Engineering & Computer Science (AREA)
  • Reciprocating Pumps (AREA)
US12/611,293 2008-11-05 2009-11-03 Process for Peristaltic Pump Control Abandoned US20100135824A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP08450172.5 2008-11-05
EP08450172A EP2184492B1 (de) 2008-11-05 2008-11-05 Verfahren zur Peristaltikpumpensteuerung

Publications (1)

Publication Number Publication Date
US20100135824A1 true US20100135824A1 (en) 2010-06-03

Family

ID=40328948

Family Applications (1)

Application Number Title Priority Date Filing Date
US12/611,293 Abandoned US20100135824A1 (en) 2008-11-05 2009-11-03 Process for Peristaltic Pump Control

Country Status (3)

Country Link
US (1) US20100135824A1 (de)
EP (1) EP2184492B1 (de)
AT (1) ATE538312T1 (de)

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20120193290A1 (en) * 2011-02-01 2012-08-02 Fresenius Medical Care Deutschland Gmbh Method and device for controlling an extracorporeal blood treatment apparatus
WO2014041361A1 (en) * 2012-09-14 2014-03-20 Vapourtec Limited Peristaltic pump and method of controlling a peristaltic pump
CN105708580A (zh) * 2016-04-12 2016-06-29 浙江大学 一种温控型智能辅助供液系统
CN108457845A (zh) * 2018-04-02 2018-08-28 汉仲坤（上海）控制系统有限公司 智能软管泵
CN114002986A (zh) * 2021-11-02 2022-02-01 保定创锐泵业有限公司 一种防爆型蠕动泵智能控制系统
EP4036410A1 (de) * 2021-01-29 2022-08-03 Masterflex, LLC Genaue volumenabgabe mittels pumpe und flusssensor
CN114962229A (zh) * 2021-08-20 2022-08-30 保定雷弗流体科技有限公司 一种蠕动泵的流量控制方法及装置

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101963146B (zh) * 2010-10-25 2012-06-06 哈尔滨工程大学 恒流蠕动泵
CN207454227U (zh) * 2017-10-31 2018-06-05 四川南格尔生物科技有限公司 一种高精度蠕动泵流速控制系统

Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3628891A (en) * 1970-09-14 1971-12-21 Technicon Corp Method for the minimization of the effects of pulsations in intermittent pumping systems
US3909136A (en) * 1972-08-09 1975-09-30 Rank Organisation Ltd Method and apparatus for measuring the optical characteristics of a flowing liquid stream
US4910682A (en) * 1984-12-14 1990-03-20 Cole-Parmer Instrument Company Method of calibrating and determining the rotational and fluid delivery velocities of a peristaltic fluid pump
US4952372A (en) * 1987-07-14 1990-08-28 The Perkin Elmer Corporation Flow injection apparatus for carrying out chemical analyses
US5316444A (en) * 1993-04-29 1994-05-31 Wicnienski Michael F Pump control and method of pumping
US5716194A (en) * 1994-09-12 1998-02-10 Ivac Medical Systems, Inc. System for increasing flow uniformity
US6158965A (en) * 1996-07-30 2000-12-12 Alaris Medical Systems, Inc. Fluid flow resistance monitoring system
US20050209563A1 (en) * 2004-03-19 2005-09-22 Peter Hopping Cassette-based dialysis medical fluid therapy systems, apparatuses and methods

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5134079A (en) 1989-03-27 1992-07-28 International Technidyne Corp. Fluid sample collection and delivery system and methods particularly adapted for body fluid sampling
JPH06197964A (ja) * 1992-06-09 1994-07-19 Sumio Kobane 脈流及び流量を制御した医療用輸液装置
JP3905291B2 (ja) * 1999-10-06 2007-04-18 株式会社ニデック 眼科用灌流吸引装置
US6691047B1 (en) * 2000-03-16 2004-02-10 Aksys, Ltd. Calibration of pumps, such as blood pumps of dialysis machine
US20070059184A1 (en) * 2005-09-15 2007-03-15 Bach David T Flow optical analysis for peristaltic and other rotary pumps
US20070217919A1 (en) * 2006-03-14 2007-09-20 Alcon, Inc. Peristaltic pump

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3628891A (en) * 1970-09-14 1971-12-21 Technicon Corp Method for the minimization of the effects of pulsations in intermittent pumping systems
US3909136A (en) * 1972-08-09 1975-09-30 Rank Organisation Ltd Method and apparatus for measuring the optical characteristics of a flowing liquid stream
US4910682A (en) * 1984-12-14 1990-03-20 Cole-Parmer Instrument Company Method of calibrating and determining the rotational and fluid delivery velocities of a peristaltic fluid pump
US4952372A (en) * 1987-07-14 1990-08-28 The Perkin Elmer Corporation Flow injection apparatus for carrying out chemical analyses
US5316444A (en) * 1993-04-29 1994-05-31 Wicnienski Michael F Pump control and method of pumping
US5716194A (en) * 1994-09-12 1998-02-10 Ivac Medical Systems, Inc. System for increasing flow uniformity
US6158965A (en) * 1996-07-30 2000-12-12 Alaris Medical Systems, Inc. Fluid flow resistance monitoring system
US20050209563A1 (en) * 2004-03-19 2005-09-22 Peter Hopping Cassette-based dialysis medical fluid therapy systems, apparatuses and methods

Cited By (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20120193290A1 (en) * 2011-02-01 2012-08-02 Fresenius Medical Care Deutschland Gmbh Method and device for controlling an extracorporeal blood treatment apparatus
US9089639B2 (en) * 2011-02-01 2015-07-28 Fresenius Medical Care Deutschland Gmbh Method and device for controlling an extracorporeal blood treatment apparatus
WO2014041361A1 (en) * 2012-09-14 2014-03-20 Vapourtec Limited Peristaltic pump and method of controlling a peristaltic pump
US20150240802A1 (en) * 2012-09-14 2015-08-27 Vapourtec Limited Pump
CN105708580A (zh) * 2016-04-12 2016-06-29 浙江大学 一种温控型智能辅助供液系统
CN108457845A (zh) * 2018-04-02 2018-08-28 汉仲坤（上海）控制系统有限公司 智能软管泵
EP4036410A1 (de) * 2021-01-29 2022-08-03 Masterflex, LLC Genaue volumenabgabe mittels pumpe und flusssensor
US20220243719A1 (en) * 2021-01-29 2022-08-04 Masterflex, Llc Accurate volume dispensing using pump and flow sensor
US11846279B2 (en) * 2021-01-29 2023-12-19 Masterflex, Llc Accurate volume dispensing using pump and flow sensor
CN114962229A (zh) * 2021-08-20 2022-08-30 保定雷弗流体科技有限公司 一种蠕动泵的流量控制方法及装置
CN114002986A (zh) * 2021-11-02 2022-02-01 保定创锐泵业有限公司 一种防爆型蠕动泵智能控制系统

Also Published As

Publication number Publication date
EP2184492A1 (de) 2010-05-12
EP2184492B1 (de) 2011-12-21
ATE538312T1 (de) 2012-01-15

Similar Documents

Publication Publication Date Title
US20100135824A1 (en) Process for Peristaltic Pump Control
US9547293B2 (en) Control system for electromagnetic pumps
EP1777515B1 (de) Durchflussmesser mit einer Messvorrichtung und einer Steuereinheit
US10036697B2 (en) Flow rate balanced, dynamically adjustable sheath delivery system for flow cytometry
JP4959565B2 (ja) 低流量動作を可能にするためのｈｐｌｃ定流量ポンプの閉ループ流量制御
US9631611B2 (en) System and method for operation of a pump
US8029247B2 (en) System and method for pressure compensation in a pump
US7426875B1 (en) Low flow rate measurement and control
JP6635915B2 (ja) 脈動が減じられたペリスタルティックポンプ及びペリスタルティックポンプの使用
EP2917581B1 (de) Peristaltische pumpe und steuerungsverfahren für eine peristaltische pumpe
CN106092216B (zh) 用于测量流体的时间分辨的流量过程的系统
RU2013148950A (ru) Система розлива с дозированием продуктов
US11542937B2 (en) Tube pump system and method for controlling the tube pump system
US20140010667A1 (en) Device and method for uptake or release of a liquid
EP2745310B1 (de) System und verfahren zum nachweis von luft in einer flüssigkeit
EP3889516B1 (de) Systeme und verfahren zur charakterisierung von ventilen mit variablem luftvolumen (vav) zur verwendung in hlk-systemen
US20190154019A1 (en) Coating agent pump
US9989048B2 (en) End of stroke detection for plunger velocity correction
GB2454783A (en) HPLC constant flow pump to enable low-flow operation, wherein thermal-based sensors are contained within an isothermal block
US20230249177A1 (en) Microfluidic liquid delivery device
US20220334044A1 (en) Flow instrument
JP3618456B2 (ja) 液体材料供給装置の流量制御機構
RU1779781C (ru) Способ измерени величины подачи объемного насоса с клапанным распределением
CN113474557A (zh) 电动隔膜泵隔膜的位置确定方法
WO2009034290A1 (en) Powered flow meter

Legal Events

Date Code Title Description
AS Assignment

Owner name: ROCHE DIAGNOSTICS GRAZ GMBH,AUSTRIA

Free format text: ASSIGNMENT OF ASSIGNORS INTEREST;ASSIGNORS:ICKINGER, SIMON;BARTEL, ARNOLD;REEL/FRAME:023934/0887

Effective date: 20100111

Owner name: ROCHE DIAGNOTICS OPERATIONS, INC.,INDIANA

Free format text: ASSIGNMENT OF ASSIGNORS INTEREST;ASSIGNOR:ROCHE DIAGNOTICS GRAZ GMBH;REEL/FRAME:023934/0893

Effective date: 20100112

STCB Information on status: application discontinuation

Free format text: ABANDONED -- FAILURE TO PAY ISSUE FEE