US20050065553A1 - Applications of vagal stimulation - Google Patents

Applications of vagal stimulation Download PDF

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Publication number
US20050065553A1
US20050065553A1 US10/866,601 US86660104A US2005065553A1 US 20050065553 A1 US20050065553 A1 US 20050065553A1 US 86660104 A US86660104 A US 86660104A US 2005065553 A1 US2005065553 A1 US 2005065553A1
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US
United States
Prior art keywords
current
subject
applying
control unit
configuring
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
US10/866,601
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English (en)
Inventor
Omry Ben Ezra
Ehud Cohen
Tamir Ben David
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
BioControl Medical BCM Ltd
Medtronic Inc
Original Assignee
BioControl Medical Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to US10/866,601 priority Critical patent/US20050065553A1/en
Application filed by BioControl Medical Ltd filed Critical BioControl Medical Ltd
Assigned to BIOCONTROL MEDICAL LTD. reassignment BIOCONTROL MEDICAL LTD. ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors: DABBY, RON, BEN EZRA, OMRY, BEN DAVID, TAMIR, COHEN, EHUD
Publication of US20050065553A1 publication Critical patent/US20050065553A1/en
Priority to US11/359,266 priority patent/US8036745B2/en
Priority to US11/657,784 priority patent/US8204591B2/en
Priority to US11/724,899 priority patent/US8060197B2/en
Priority to US11/975,241 priority patent/US20080125819A1/en
Priority to US11/975,169 priority patent/US7668602B2/en
Priority to US11/975,240 priority patent/US7778702B2/en
Priority to US11/978,776 priority patent/US8116881B2/en
Assigned to BIO CONTROL MEDICAL (B.C.M.) LTD. reassignment BIO CONTROL MEDICAL (B.C.M.) LTD. CHANGE OF NAME (SEE DOCUMENT FOR DETAILS). Assignors: BIOCONTROL MEDICAL LTD.
Assigned to MEDTRONIC, INC. reassignment MEDTRONIC, INC. SECURITY AGREEMENT Assignors: BIO CONTROL MEDICAL (B.C.M.) LTD
Priority to US13/493,499 priority patent/US20120303080A1/en
Priority to US14/243,262 priority patent/US20140214135A1/en
Assigned to MEDTRONIC, INC. reassignment MEDTRONIC, INC. ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors: BIOCONTROL ,EDICAL (B.C.M.) LTD
Abandoned legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
    • A61N1/3606—Implantable neurostimulators for stimulating central or peripheral nerve system adapted for a particular treatment
    • A61N1/36114—Cardiac control, e.g. by vagal stimulation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
    • A61N1/36053—Implantable neurostimulators for stimulating central or peripheral nerve system adapted for vagal stimulation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/38—Applying electric currents by contact electrodes alternating or intermittent currents for producing shock effects
    • A61N1/39—Heart defibrillators
    • A61N1/3956—Implantable devices for applying electric shocks to the heart, e.g. for cardioversion
    • A61N1/3962—Implantable devices for applying electric shocks to the heart, e.g. for cardioversion in combination with another heart therapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/38—Applying electric currents by contact electrodes alternating or intermittent currents for producing shock effects
    • A61N1/39—Heart defibrillators
    • A61N1/3956—Implantable devices for applying electric shocks to the heart, e.g. for cardioversion
    • A61N1/3962—Implantable devices for applying electric shocks to the heart, e.g. for cardioversion in combination with another heart therapy
    • A61N1/39622—Pacing therapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/38—Applying electric currents by contact electrodes alternating or intermittent currents for producing shock effects
    • A61N1/39—Heart defibrillators
    • A61N1/3956—Implantable devices for applying electric shocks to the heart, e.g. for cardioversion
    • A61N1/3962—Implantable devices for applying electric shocks to the heart, e.g. for cardioversion in combination with another heart therapy
    • A61N1/39624—Pain reduction therapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
    • A61N1/3606—Implantable neurostimulators for stimulating central or peripheral nerve system adapted for a particular treatment
    • A61N1/36114—Cardiac control, e.g. by vagal stimulation
    • A61N1/36117—Cardiac control, e.g. by vagal stimulation for treating hypertension
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/362—Heart stimulators
    • A61N1/3621—Heart stimulators for treating or preventing abnormally high heart rate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/38—Applying electric currents by contact electrodes alternating or intermittent currents for producing shock effects
    • A61N1/39—Heart defibrillators
    • A61N1/395—Heart defibrillators for treating atrial fibrillation
US10/866,601 2002-05-23 2004-06-10 Applications of vagal stimulation Abandoned US20050065553A1 (en)

Priority Applications (10)

Application Number Priority Date Filing Date Title
US10/866,601 US20050065553A1 (en) 2003-06-13 2004-06-10 Applications of vagal stimulation
US11/359,266 US8036745B2 (en) 2004-06-10 2006-02-21 Parasympathetic pacing therapy during and following a medical procedure, clinical trauma or pathology
US11/657,784 US8204591B2 (en) 2002-05-23 2007-01-24 Techniques for prevention of atrial fibrillation
US11/724,899 US8060197B2 (en) 2003-05-23 2007-03-16 Parasympathetic stimulation for termination of non-sinus atrial tachycardia
US11/975,241 US20080125819A1 (en) 2003-06-13 2007-10-17 Parasympathetic stimulation for heart conditions
US11/975,169 US7668602B2 (en) 2003-06-13 2007-10-17 Minimal-heart-rate reduction parasympathetic stimulation
US11/975,240 US7778702B2 (en) 2003-06-13 2007-10-17 Combined parasympathetic stimulation and drug therapy
US11/978,776 US8116881B2 (en) 2004-06-10 2007-10-29 Electrode assembly for nerve control
US13/493,499 US20120303080A1 (en) 2003-06-13 2012-06-11 Parasympathetic nerve stimulation
US14/243,262 US20140214135A1 (en) 2002-05-23 2014-04-02 Dissolvable electrode device

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US47857603P 2003-06-13 2003-06-13
US10/866,601 US20050065553A1 (en) 2003-06-13 2004-06-10 Applications of vagal stimulation

Related Parent Applications (2)

Application Number Title Priority Date Filing Date
US11/234,877 Continuation-In-Part US7885709B2 (en) 2001-08-31 2005-09-22 Nerve stimulation for treating disorders
US13/939,892 Continuation-In-Part US8725271B2 (en) 2002-05-23 2013-07-11 Electrode device with elongated electrode

Related Child Applications (7)

Application Number Title Priority Date Filing Date
US11/022,011 Continuation-In-Part US7561922B2 (en) 2002-05-23 2004-12-22 Construction of electrode assembly for nerve control
US11/359,266 Continuation-In-Part US8036745B2 (en) 2002-05-23 2006-02-21 Parasympathetic pacing therapy during and following a medical procedure, clinical trauma or pathology
US11/560,654 Continuation-In-Part US7759011B2 (en) 2005-11-17 2006-11-16 Safety system for reducing the explosion risk of a fuel tank
US11/657,784 Continuation-In-Part US8204591B2 (en) 2002-05-23 2007-01-24 Techniques for prevention of atrial fibrillation
US11/975,169 Continuation US7668602B2 (en) 2003-06-13 2007-10-17 Minimal-heart-rate reduction parasympathetic stimulation
US11/975,240 Continuation US7778702B2 (en) 2003-06-13 2007-10-17 Combined parasympathetic stimulation and drug therapy
US11/975,241 Continuation US20080125819A1 (en) 2003-06-13 2007-10-17 Parasympathetic stimulation for heart conditions

Publications (1)

Publication Number Publication Date
US20050065553A1 true US20050065553A1 (en) 2005-03-24

Family

ID=33551836

Family Applications (4)

Application Number Title Priority Date Filing Date
US10/866,601 Abandoned US20050065553A1 (en) 2002-05-23 2004-06-10 Applications of vagal stimulation
US11/975,169 Active 2024-09-15 US7668602B2 (en) 2003-06-13 2007-10-17 Minimal-heart-rate reduction parasympathetic stimulation
US11/975,240 Expired - Fee Related US7778702B2 (en) 2003-06-13 2007-10-17 Combined parasympathetic stimulation and drug therapy
US11/975,241 Abandoned US20080125819A1 (en) 2003-06-13 2007-10-17 Parasympathetic stimulation for heart conditions

Family Applications After (3)

Application Number Title Priority Date Filing Date
US11/975,169 Active 2024-09-15 US7668602B2 (en) 2003-06-13 2007-10-17 Minimal-heart-rate reduction parasympathetic stimulation
US11/975,240 Expired - Fee Related US7778702B2 (en) 2003-06-13 2007-10-17 Combined parasympathetic stimulation and drug therapy
US11/975,241 Abandoned US20080125819A1 (en) 2003-06-13 2007-10-17 Parasympathetic stimulation for heart conditions

Country Status (3)

Country Link
US (4) US20050065553A1 (fr)
EP (1) EP1648558A4 (fr)
WO (1) WO2004110549A2 (fr)

Cited By (196)

* Cited by examiner, † Cited by third party
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US20030055464A1 (en) * 1999-03-05 2003-03-20 Nissim Darvish Blood glucose level control
US20050125044A1 (en) * 2000-05-23 2005-06-09 North Shore-Long Island Jewish Research Institute Inhibition of inflammatory cytokine production by cholinergic agonists and vagus nerve stimulation
US20050149127A1 (en) * 2003-12-24 2005-07-07 Imad Libbus Automatic baroreflex modulation responsive to adverse event
US20050149126A1 (en) * 2003-12-24 2005-07-07 Imad Libbus Baroreflex stimulation to treat acute myocardial infarction
US20050149155A1 (en) * 2003-12-24 2005-07-07 Avram Scheiner Stimulation lead for stimulating the baroreceptors in the pulmonary artery
US20050149143A1 (en) * 2003-12-24 2005-07-07 Imad Libbus Baroreflex stimulator with integrated pressure sensor
US20050251212A1 (en) * 2000-09-27 2005-11-10 Cvrx, Inc. Stimulus regimens for cardiovascular reflex control
US20050282906A1 (en) * 2004-03-25 2005-12-22 North Shore-Long Island Jewish Research Institute Neural tourniquet
US20060025829A1 (en) * 2004-07-28 2006-02-02 Armstrong Randolph K Power supply monitoring for an implantable device
US20060047325A1 (en) * 2004-07-26 2006-03-02 Mark Thimineur Stimulation system and method for treating a neurological disorder
US20060184207A1 (en) * 1999-03-05 2006-08-17 Metacure N.V. Blood glucose level control
US20060217772A1 (en) * 2005-03-23 2006-09-28 Cardiac Pacemakers, Inc. System to provide myocardial and neural stimulation
US20060222667A1 (en) * 2003-05-13 2006-10-05 The Foundry, Inc. Apparatus for treating asthma using neurotoxin
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US20060241725A1 (en) * 2005-04-25 2006-10-26 Imad Libbus Method and apparatus for simultaneously presenting cardiac and neural signals
US20060259107A1 (en) * 2005-05-16 2006-11-16 Anthony Caparso System for selective activation of a nerve trunk using a transvascular reshaping lead
US20070021794A1 (en) * 2000-09-27 2007-01-25 Cvrx, Inc. Baroreflex Therapy for Disordered Breathing
US20070027496A1 (en) * 2005-07-28 2007-02-01 Cyberonics, Inc. Stimulating cranial nerve to treat pulmonary disorder
US20070060972A1 (en) * 2000-09-27 2007-03-15 Cvrx, Inc. Devices and methods for cardiovascular reflex treatments
US20070106337A1 (en) * 2005-11-10 2007-05-10 Electrocore, Inc. Methods And Apparatus For Treating Disorders Through Neurological And/Or Muscular Intervention
US20070185542A1 (en) * 2002-03-27 2007-08-09 Cvrx, Inc. Baroreflex therapy for disordered breathing
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US20070191905A1 (en) * 2006-02-10 2007-08-16 Electrocore, Inc. Electrical stimulation treatment of hypotension
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US20070233194A1 (en) * 2006-03-29 2007-10-04 Catholic Healthcare West (D/B/A St. Joseph's Hospital And Medical Center) Synchronization of vagus nerve stimulation with the cardiac cycle of a patient
US20070260283A1 (en) * 2006-05-08 2007-11-08 Dan Li Method and device for providing anti-tachyarrhythmia therapy
US20080004672A1 (en) * 2006-06-30 2008-01-03 Yousufali Dalal System for providing diabetic therapy
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US20080125843A1 (en) 2008-05-29
EP1648558A2 (fr) 2006-04-26
WO2004110549A3 (fr) 2005-03-31
US20080275514A1 (en) 2008-11-06
EP1648558A4 (fr) 2015-05-27
US7778702B2 (en) 2010-08-17
US7668602B2 (en) 2010-02-23
US20080125819A1 (en) 2008-05-29

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