US20040204705A1 - Cryotreatment devices and methods of forming conduction blocks - Google Patents
Cryotreatment devices and methods of forming conduction blocks Download PDFInfo
- Publication number
- US20040204705A1 US20040204705A1 US10/411,601 US41160103A US2004204705A1 US 20040204705 A1 US20040204705 A1 US 20040204705A1 US 41160103 A US41160103 A US 41160103A US 2004204705 A1 US2004204705 A1 US 2004204705A1
- Authority
- US
- United States
- Prior art keywords
- ablation
- distal portion
- medical device
- tissue
- lumen
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B18/02—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by cooling, e.g. cryogenic techniques
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B18/02—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by cooling, e.g. cryogenic techniques
- A61B18/0218—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by cooling, e.g. cryogenic techniques with open-end cryogenic probe, e.g. for spraying fluid directly on tissue or via a tissue-contacting porous tip
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B18/02—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by cooling, e.g. cryogenic techniques
- A61B2018/0212—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by cooling, e.g. cryogenic techniques using an instrument inserted into a body lumen, e.g. catheter
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B18/02—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by cooling, e.g. cryogenic techniques
- A61B2018/0231—Characteristics of handpieces or probes
- A61B2018/0262—Characteristics of handpieces or probes using a circulating cryogenic fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B18/02—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by cooling, e.g. cryogenic techniques
- A61B2018/0293—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by cooling, e.g. cryogenic techniques using an instrument interstitially inserted into the body, e.g. needle
Definitions
- the present invention relates generally to medical devices for ablating tissue at one or more target sites. More specifically, the present invention relates to cryotreatment devices and methods for inducing controlled necrosis of cardiac tissue within the heart.
- Cardiac arrhythmias such as atrial fibrillation, bradycardia, ventricular tachycardia, ventricle fibrillation, and Wolff-Parkinson-White syndrome are common heart abnormalities that cause stroke, myocardial infarction, and other thromboembolic events within the body.
- the heart In patients with normal sinus rhythm, the heart is electrically excited to beat in a synchronous and patterned manner, typically at a rate of 60 to 100 beats per minute (bpm).
- bpm beats per minute
- abnormal regions of the cardiac tissue may aberrantly conduct to adjacent tissue, causing the heart to beat irregularly.
- ventricular tachycardia for example, electrical signals may be errantly received in the lower heart chamber (i.e. the ventricle) instead of the right, upper chamber (i.e. the atria), causing the heart to beat rapidly.
- the upper chambers of the heart beat at an uncontrolled rate of 350 to 600 bpm, which results in a reduction of the pumping force of the heart.
- blood in the heart chambers may become stagnant and pool, forming blood clots that can dislodge within the body and cause stroke or other life threatening events.
- a catheter loaded with a cryogenic cooling fluid may be used to cryogenically cool cardiac tissue at strategic locations of the heart, such as the right and left atria, or the pulmonary veins.
- the catheter can be used to induce necrosis at one or more pre-mapped target sites within the heart to create conduction blocks within the aberrant electrical conduction pathways.
- necrosis of one or more target sites within the atrial cardiac muscle tissue can be used to block the electrical signals believed to cause and/or sustain the fibrillation.
- cryotreatment device to form the required conduction block may be ineffective since there is no adequate means to control the transmural depth of the lesion, or the distance between each lesion.
- many cryotreatment devices utilize relatively large catheter tips, which destroy more tissue than is necessary to form the conduction block and further reduce the already weakened pumping force of the heart. It is therefore desirable to have a cryotreatment device capable of transmurally controlling the depth of each lesion and in a contiguous manner.
- a cryotreatment device in accordance with an exemplary embodiment of the present invention may comprise an elongated member having a proximal portion, a distal portion, and one or more lumens therein in fluid communication with a cooling fluid adapted to cool the distal portion of the elongated member.
- the elongated member may include one or more needle-like ablation tips configured to pierce and necrotize cardiac tissue within the heart, preventing the conduction of aberrant electrical signals through the tissue to one or more relay sites of arrthymogenic foci.
- the cryotreatment device may include one or more features configured to form an array of ablations within the cardiac tissue, forming a contiguous line of conduction block.
- the ablation tips may be retractable within the elongated member to control the penetration depth of the tips transmurally into the cardiac tissue.
- a pull cord operatively coupled to the ablation tip can be used to retract the ablation tip from the cardiac tissue.
- An ultrasonic probe or other measuring device may also be provided to measure and control the insertion depth of the cryotreatment device within the cardiac tissue.
- a cryosurgical method in accordance with the present invention may comprise the steps of providing a cryotreatment device to a target site within the heart, and necrotizing one or more locations within the cardiac tissue to form a contiguous line of conduction block.
- a cooling fluid such as liquid nitrous oxide can be injected through an inner lumen extending to the distal portion of the cryotreatment device to cool the surrounding tissue adjacent the ablation tips.
- FIG. 1 is an illustration of a cryotreatment device in accordance with an exemplary embodiment of the present invention, wherein the device is shown inserted through the septal wall of the heart and advanced to a target site at or near one or more relay points;
- FIG. 2 is a partial cross-sectional view of the cryotreatment device of FIG. 1;
- FIG. 3 is a detailed view of the cryotreatment device of FIGS. 1-2, wherein the device includes an ultrasonic probe adapted measure and control the transmural depth of the device into the cardiac tissue;
- FIG. 4 is another detailed view illustrating multiple cryotreatment devices coupled together using a coupling member
- FIG. 5 is a view of a cryotreatment device in accordance with an exemplary embodiment of the present invention, wherein the cryotreatment device includes a linear array of ablation tips;
- FIG. 6 is a partial cross-sectional view of a cryotreatment device in accordance with an exemplary embodiment of the present invention, wherein the cryotreatment device includes several retractable cryogenic tips configured to form a circumferential line of conduction block within the heart; and
- FIG. 7 is a partial cross-sectional view of a cryotreatment device in accordance with another exemplary embodiment of the present invention, wherein the cryotreatment devices includes an enlarged distal portion with retractable ablation tips.
- FIG. 1 is an illustrative view of a cryotreatment device 10 in accordance with an exemplary embodiment of the present invention for inducing controlled necrosis at one or more pre-mapped target sites within the heart.
- a guide wire 12 inserted percutaneously into the femoral or jugular veins is shown advanced through the septal wall 14 and into the upper chambers 16 , 18 of a heart 20 .
- guidewire 12 can be advanced to a location distal a target site 22 determined to cause electrical interference with one or more downstream arrythmogenic foci 24 .
- a guide catheter 26 sufficiently sized to receive cryotreatment device 10 can be used to advance the cryotreatment device 10 to a location at or near the target site 22 .
- Arrhythmias such as atrial flutter, atrial fibrillation and ventricular tachycardia are typically caused when abnormal regions of the heart transmit aberrant electrical signals vis-à-vis arrythmogenic foci.
- a cryotreatment device in accordance with the present invention can be inserted into cardiac tissue at a pre-mapped target site and cooled to a temperature of about ⁇ 40 to ⁇ 100° C. to induce necrosis at one or more locations 28 , 30 , 32 , 34 within the heart, such as the pulmonary vein 36 .
- the cryotreatment device can be inserted at the various locations 28 , 30 , 32 , 34 to form a line of conduction block that prevents certain electrical signals from being sent from the foci points 24 .
- the transmission of aberrant signals believed to cause the arrhythmia can be reduced or in some cases altogether eliminated.
- FIG. 2 is a partial cross-sectional view of the cryotreatment device 10 of FIG. 1, showing the distal portion 38 of the device 10 in greater detail.
- cryotreatment device 10 comprises a multiple lumen catheter body 40 having an outer shaft 42 configured to pierce and cool the cardiac tissue, and an inner shaft 44 defining an inner lumen 46 in fluid communication with a cooling fluid.
- the outer shaft 42 of catheter body 40 may have a transverse cross-sectional area that is substantially circular in shape, extending from a proximal end (not shown) located outside of the patient's body to a transition region 48 on the catheter body 40 .
- catheter body 40 tapers distally to a needle-like ablation tip 50 configured to pierce and contact cardiac tissue.
- cryotreatment device 10 can be placed in fluid communication with a cooling fluid such as liquid nitrogen, nitrous oxide (N 2 O), carbon dioxide (C 2 O), chlorodifluoromethane, polydimethysiloxane, ethyl alcohol, chlorofluorocarbons (Freon), or other suitable fluid.
- a cooling fluid such as liquid nitrogen, nitrous oxide (N 2 O), carbon dioxide (C 2 O), chlorodifluoromethane, polydimethysiloxane, ethyl alcohol, chlorofluorocarbons (Freon), or other suitable fluid.
- the cooling fluid can be delivered in either a liquid or gas state through inner lumen 46 , and injected into the annular space 52 between the outer and inner shafts 42 , 44 through several apertures 54 disposed in the inner shaft 44 .
- pressurized liquid nitrous oxide can be fluidly coupled to the inner lumen 46 of catheter body 40 , and ejected through several apertures 54 disposed in the inner lumen 44 .
- the apertures 54 are adapted to act as a throttling element (e.g. a throttling nozzle) for the cryogen, producing isenthalpic cooling as the fluid is expended from a relatively high pressure within the inner lumen 46 to a lower pressure as it enters the annular space 52 .
- cryogenic fluid expands as it passes through the apertures 54 , it transitions to a gas and impinges upon the interior wall 56 of the outer shaft 42 cooling the distal portion 38 of the catheter body 40 . This temperature drop is then thermally transferred through the catheter body 40 and into the surrounding cardiac tissue 58 , inducing necrosis at the target site 22 . The cryogenic fluid is subsequently returned through annular lumen 52 to the proximal end of the device 10 .
- cryotreatment device 10 includes several equidistantly spaced apertures 54 configured to provide uniform cooling through the distal portion 38 of the catheter body 40 . It should be recognized, however, that the apertures 54 could be placed at any number of strategic locations, at either equidistant or non-equidistant intervals, to direct the cryogenic fluid to a particular location within the device 10 .
- the outer and inner shafts 42 , 44 of cryotreatment device 10 may be fabricated from materials having certain desirable flexibility and thermodynamic properties.
- the outer and inner shafts 42 , 44 may each be formed of a superelastic material such as nickel-titanium alloy (Nitinol) to permit the cryotreatment device 10 to be inserted through relatively tortuous locations of the body without kinking.
- a superelastic material such as nickel-titanium alloy (Nitinol) to permit the cryotreatment device 10 to be inserted through relatively tortuous locations of the body without kinking.
- Other suitable biocompatible materials such stainless steel or a polymer/metal composition may also be utilized, depending on the particular application.
- cryotreatment device 10 can be inserted through a previously positioned guide catheter 26 and advanced to a pre-mapped target site 22 within the heart believed to transmit aberrant electrical signals to one or more relay points.
- needle-like ablation tip 50 of device 10 can be configured to pierce and contact the cardiac tissue 58 of pulmonary vein 36 , allowing the distal portion 38 of catheter body 40 to be inserted into the cardiac tissue 58 .
- a curved portion 60 on the catheter body 40 may be adapted to orient the needle-like ablation tip 50 in a direction substantially perpendicular to the tissue wall 58 .
- cryotreatment device 10 can be configured to measure and control the transmural depth at which the device is inserted into the cardiac tissue 58 .
- Controlled insertion of the needle-tip ablation tip 50 into the cardiac tissue 58 prevents distension of the vein 36 from occurring, and prevents the ablation of cardiac tissue not necessary to form the conduction block.
- Controlled insertion of the needle-like ablation tip 50 into the cardiac tissue 58 also ensures that the cryotreatment device 10 is inserted at a sufficient depth to form the desired conduction block.
- An ultrasonic probe 62 or other measurement device may be utilized to measure the precise depth at which cryotreatment device 10 is inserted into the cardiac tissue 58 .
- the ultrasonic probe 62 can be coupled to catheter body 40 a predetermined distance from the needle-like ablation tip 50 , and engaged to acoustically measure the depth at which the distal portion 38 is inserted into the cardiac tissue 58 .
- the ultrasonic probe 62 may be coupled to the catheter body 40 , or may be formed as a separate element that can be advanced along the catheter body 40 and positioned proximal the cardiac tissue 58 .
- the ultrasonic probe 62 may act as a guiding member for the device 10 , eliminating the need for a separate guide catheter.
- cryotreatment device 10 may be employed, including, for example, the use of an optical probe, acoustic reflective coatings, distal bipolar electrodes, or through the use radiographic techniques such as fluoroscopic marker bands.
- a fluid controller or other similar device can be coupled to the proximal end of the cryotreatment device 10 and used to inject a controlled flow of cryogenic fluid (e.g. liquid N 2 O) through the inner lumen 46 .
- a controlled flow of cryogenic fluid e.g. liquid N 2 O
- One or more temperature sensors (not shown) on the distal portion 38 of catheter body 40 may also optionally be used to monitor the temperature of the device 10 and adjust the flow rate via the fluid controller, as necessary.
- An insulated sleeve 64 surrounding the catheter body 40 may be utilized to thermally isolate the catheter body 40 proximal the distal portion 38 to prevent ablating other areas of the body.
- the cryotreatment device may include a coupling member configured to couple multiple ablation tips together in an array.
- a coupling member 66 can be used to connect multiple cryotreatment devices 10 together, forming a linear array of needle-like ablation tips 50 that, when thermally cooled via a cryogenic fluid, create a line of contiguous conduction block along the cardiac tissue 58 at the target site 22 .
- the coupling member 66 can be configured to couple together any number of cryotreatment devices together in any desired array or pattern.
- the multiple cooling members 10 applied in a sequential cooling method will allow the lesions to be made in a stitched like fashion to ensure contiguous connection of all the lesions.
- the method of stitching is accomplished by moving one needle 50 while the other needle 50 ′ is anchored and froze into the tissue.
- the sequence of operation would be as follows:
- FIG. 5 is a view of a cryotreatment device 68 in accordance with another exemplary embodiment of the present invention.
- Cryotreatment 68 comprises a catheter body 70 having several linearly disposed ablation tips 72 along a distal portion 74 that, when placed into fluid communication with a cryogenic cooling fluid, are configured to form a line of conduction block within a target site of the heart.
- Each ablation tip 72 may be configured similar to tip 50 described above, having a needle-like shape configured to pierce and contact the cardiac tissue when inserted.
- the number of needles 72 and lumens 76 may be the same as shown, or may be as few as two needles 72 for any number of lumens 76 in the method previously described.
- An inner lumen 76 in fluid communication with a source of pressurized cryogen at or near the proximal end of the device 70 is configured to cool each ablation tip 72 in a manner similar that described above with respect to cryotreatment device 10 .
- the cryotreatment device 70 may also optionally include an ultrasonic probe or other measurement means (not shown) for measuring the precise depth at which the ablations tips 72 are transmurally inserted into the cardiac tissue.
- An insulation layer 78 surrounding the catheter body 70 thermally insulates the body 70 from ablating other areas of the body.
- ablation tips 72 can be aligned with a portion of the cardiac tissue believed to transfer the aberrant electrical signal(s) to one or more downstream relay points, and inserted into the tissue at a controlled depth.
- a pressurized cryogenic fluid can be delivered through the catheter body 70 , causing the ablation tips 72 on the distal portion 74 to undergo a temperature drop to a temperature of about ⁇ 40 to ⁇ 100° C., inducing necrosis in the surrounding cardiac tissue.
- a cryotreatment device in accordance with the present invention may be configured to form a circumferential line of conduction blocks at a target site within the heart.
- a cryotreatment device 80 in accordance with the present invention may include a catheter body 82 having several needle-like ablation tips 84 on distal end 86 that, when thermally cooled via a supplied source of cryogenic fluid, form a circumferential line of conduction block at a target site within the heart (e.g. about a pulmonary vein).
- Cryotreatment device 80 may comprise an outer shaft 88 , and an inner shaft 90 disposed within the outer shaft 88 .
- the inner shaft 90 can be configured to deliver a pressurized source of cryogenic fluid such as liquid nitrogen or N 2 O through aperture 92 towards the interior surface 94 of distal end 86 , causing the interior surface 94 of the distal end 86 of catheter body 82 to cool and conduct heat.
- a pressurized source of cryogenic fluid such as liquid nitrogen or N 2 O
- Each of the needle-like ablation tips 84 can be configured to retract through several openings 96 disposed on the distal end 86 of the catheter body 82 .
- a control wire 98 extending proximally from each ablation tip 84 to a location outside of the patient's body may be used to retract each tip 84 through its respective opening 96 , allowing the operator to adjust the precise depth at which the tip 84 is inserted the cardiac tissue.
- a flange 100 coupled to each ablation tip 84 prevents the tip 84 from being pulled proximally through opening 96 as control wire 98 is retracted.
- an ultrasonic probe or other suitable device can be utilized to measure and, if necessary, control the penetration depth of the ablation tips 84 within the tissue.
- cryotreatment device 80 can be advanced to a target site within the heart, and, with the ablation tips 84 initially in a fully deployed position, inserted into the cardiac tissue. Once the device 80 is inserted into the tissue, the operator can retract the control wire 98 proximally a distance, causing the ablation tips 84 to retract from within the tissue a slight distance (e.g. 0.5-3.0 cm). An ultrasonic probe or other suitable device may be used to measure the precise depth at which the ablation tips 84 are inserted into the cardiac tissue.
- a pressurized flow of cryogen is then delivered through the device, causing the distal end 86 of the device, including the ablation tips 84 , to cool to a temperature of about ⁇ 40 to ⁇ 100° C., forming a circumferential line of conduction block within the body.
- FIG. 7 is a partial cross-sectional view of a cryotreatment device 102 in accordance with another exemplary embodiment of the present invention.
- Cryotreatment device 102 comprises an outer shaft 104 having a proximal portion (not shown), a distal portion 106 , and an inner lumen 108 in fluid communication with a cooling fluid such as liquid N 2 O.
- the distal portion 106 of cryotreatment device 102 may be enlarged slightly, orienting several retractable needle-like ablation tips 110 in a wider radial array, permitting the formation of a circumferential line of conduction block at larger target sites.
- a control wire 112 operatively coupled to each ablation tip 110 can be utilized to adjust the transmural depth of the tip 110 into the cardiac tissue.
- a flanged portion 114 on each ablation tip 110 prevents the operator from pulling the ablation tip 110 proximally through the tip openings 116 on the distal portion 106 of the outer shaft 104 .
Landscapes
- Health & Medical Sciences (AREA)
- Surgery (AREA)
- Life Sciences & Earth Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medical Informatics (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Otolaryngology (AREA)
- Molecular Biology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Surgical Instruments (AREA)
- Ultra Sonic Daignosis Equipment (AREA)
Priority Applications (10)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US10/411,601 US20040204705A1 (en) | 2003-04-10 | 2003-04-10 | Cryotreatment devices and methods of forming conduction blocks |
EP04759260.5A EP1610702B1 (en) | 2003-04-10 | 2004-04-08 | Cryotreatment devices for forming conduction blocks |
CA002521714A CA2521714A1 (en) | 2003-04-10 | 2004-04-08 | Cryotreatment devices and methods of forming conduction blocks |
PCT/US2004/010806 WO2004091416A1 (en) | 2003-04-10 | 2004-04-08 | Cryotreatment devices and methods of forming conduction blocks |
JP2006509805A JP4653734B2 (ja) | 2003-04-10 | 2004-04-08 | 極低温治療装置及び伝導遮断箇所を形成する方法 |
US12/485,697 US8048066B2 (en) | 2003-04-10 | 2009-06-16 | Cryotreatment device and method of forming conduction blocks |
US13/252,817 US8585689B2 (en) | 2003-04-10 | 2011-10-04 | Cryotreatment devices and methods of forming conduction blocks |
US14/084,257 US9033967B2 (en) | 2003-04-10 | 2013-11-19 | Cryotreatment devices and methods of forming conduction blocks |
US14/711,232 US9339322B2 (en) | 2003-04-10 | 2015-05-13 | Cryotreatment devices and methods of forming conduction blocks |
US15/132,934 US9750556B2 (en) | 2003-04-10 | 2016-04-19 | Cryotreatment devices and methods of forming conduction blocks |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US10/411,601 US20040204705A1 (en) | 2003-04-10 | 2003-04-10 | Cryotreatment devices and methods of forming conduction blocks |
Related Child Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US12/485,697 Division US8048066B2 (en) | 2003-04-10 | 2009-06-16 | Cryotreatment device and method of forming conduction blocks |
Publications (1)
Publication Number | Publication Date |
---|---|
US20040204705A1 true US20040204705A1 (en) | 2004-10-14 |
Family
ID=33131024
Family Applications (6)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US10/411,601 Abandoned US20040204705A1 (en) | 2003-04-10 | 2003-04-10 | Cryotreatment devices and methods of forming conduction blocks |
US12/485,697 Expired - Fee Related US8048066B2 (en) | 2003-04-10 | 2009-06-16 | Cryotreatment device and method of forming conduction blocks |
US13/252,817 Expired - Fee Related US8585689B2 (en) | 2003-04-10 | 2011-10-04 | Cryotreatment devices and methods of forming conduction blocks |
US14/084,257 Expired - Lifetime US9033967B2 (en) | 2003-04-10 | 2013-11-19 | Cryotreatment devices and methods of forming conduction blocks |
US14/711,232 Expired - Fee Related US9339322B2 (en) | 2003-04-10 | 2015-05-13 | Cryotreatment devices and methods of forming conduction blocks |
US15/132,934 Expired - Lifetime US9750556B2 (en) | 2003-04-10 | 2016-04-19 | Cryotreatment devices and methods of forming conduction blocks |
Family Applications After (5)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US12/485,697 Expired - Fee Related US8048066B2 (en) | 2003-04-10 | 2009-06-16 | Cryotreatment device and method of forming conduction blocks |
US13/252,817 Expired - Fee Related US8585689B2 (en) | 2003-04-10 | 2011-10-04 | Cryotreatment devices and methods of forming conduction blocks |
US14/084,257 Expired - Lifetime US9033967B2 (en) | 2003-04-10 | 2013-11-19 | Cryotreatment devices and methods of forming conduction blocks |
US14/711,232 Expired - Fee Related US9339322B2 (en) | 2003-04-10 | 2015-05-13 | Cryotreatment devices and methods of forming conduction blocks |
US15/132,934 Expired - Lifetime US9750556B2 (en) | 2003-04-10 | 2016-04-19 | Cryotreatment devices and methods of forming conduction blocks |
Country Status (5)
Country | Link |
---|---|
US (6) | US20040204705A1 (ja) |
EP (1) | EP1610702B1 (ja) |
JP (1) | JP4653734B2 (ja) |
CA (1) | CA2521714A1 (ja) |
WO (1) | WO2004091416A1 (ja) |
Cited By (35)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20070088247A1 (en) * | 2000-10-24 | 2007-04-19 | Galil Medical Ltd. | Apparatus and method for thermal ablation of uterine fibroids |
US20070167938A1 (en) * | 2000-10-24 | 2007-07-19 | Galil Medical Ltd. | Multiple cryoprobe delivery apparatus |
WO2007135431A2 (en) * | 2006-05-24 | 2007-11-29 | Emcision Limited | Vessel sealing device and methods |
US20080045934A1 (en) * | 2000-10-24 | 2008-02-21 | Galil Medical Ltd. | Device and method for coordinated insertion of a plurality of cryoprobes |
US20080051775A1 (en) * | 2005-11-23 | 2008-02-28 | Evans David K | Multi-modal analgesia delivery system ("MADS") |
US20080051774A1 (en) * | 2001-05-21 | 2008-02-28 | Galil Medical Ltd. | Device and method for coordinated insertion of a plurality of cryoprobes |
US20080051776A1 (en) * | 2001-05-21 | 2008-02-28 | Galil Medical Ltd. | Thin uninsulated cryoprobe and insulating probe introducer |
WO2008142686A2 (en) * | 2007-05-21 | 2008-11-27 | Uc-Care Ltd. | Ablation probe |
US20080300586A1 (en) * | 2000-10-24 | 2008-12-04 | Galil Medical Ltd. | Apparatus and method for compressing a gas, and cryosurgery system and method utilizing same |
US20090005769A1 (en) * | 2004-07-27 | 2009-01-01 | Plymouth Hospitals Nhs Trust | Catheter, Apparatus for Creating a Linear Ablation and a Method of Ablating Tissue |
US20090171334A1 (en) * | 2005-05-20 | 2009-07-02 | Myoscience, Inc. | Subdermal cryogenic remodeling of muscles, nerves, connective tissue, and/or adipose tissue (fat) |
US20090292279A1 (en) * | 2006-01-26 | 2009-11-26 | Galil Medical Ltd. | Device and Method for Coordinated Insertion of a Plurality of Cryoprobes |
US20090299420A1 (en) * | 2008-06-02 | 2009-12-03 | Shuros Allan C | Method and apparatus for cryotherapy and pacing preconditioning |
US7713266B2 (en) | 2005-05-20 | 2010-05-11 | Myoscience, Inc. | Subdermal cryogenic remodeling of muscles, nerves, connective tissue, and/or adipose tissue (fat) |
US8007847B2 (en) | 2004-01-13 | 2011-08-30 | Eytan Biderman | Feeding formula appliance |
US8298216B2 (en) | 2007-11-14 | 2012-10-30 | Myoscience, Inc. | Pain management using cryogenic remodeling |
US8409185B2 (en) | 2007-02-16 | 2013-04-02 | Myoscience, Inc. | Replaceable and/or easily removable needle systems for dermal and transdermal cryogenic remodeling |
US20130184696A1 (en) * | 2012-01-13 | 2013-07-18 | Myoscience, Inc. | Cryogenic Needle with Freeze Zone Regulation |
US9017318B2 (en) | 2012-01-20 | 2015-04-28 | Myoscience, Inc. | Cryogenic probe system and method |
US9066712B2 (en) | 2008-12-22 | 2015-06-30 | Myoscience, Inc. | Integrated cryosurgical system with refrigerant and electrical power source |
US9155584B2 (en) | 2012-01-13 | 2015-10-13 | Myoscience, Inc. | Cryogenic probe filtration system |
US9241753B2 (en) | 2012-01-13 | 2016-01-26 | Myoscience, Inc. | Skin protection for subdermal cryogenic remodeling for cosmetic and other treatments |
US9254162B2 (en) | 2006-12-21 | 2016-02-09 | Myoscience, Inc. | Dermal and transdermal cryogenic microprobe systems |
US9295512B2 (en) | 2013-03-15 | 2016-03-29 | Myoscience, Inc. | Methods and devices for pain management |
US9339322B2 (en) | 2003-04-10 | 2016-05-17 | Boston Scientific Scimed Inc. | Cryotreatment devices and methods of forming conduction blocks |
US9610112B2 (en) | 2013-03-15 | 2017-04-04 | Myoscience, Inc. | Cryogenic enhancement of joint function, alleviation of joint stiffness and/or alleviation of pain associated with osteoarthritis |
US9668800B2 (en) | 2013-03-15 | 2017-06-06 | Myoscience, Inc. | Methods and systems for treatment of spasticity |
US20170333104A1 (en) * | 2016-05-19 | 2017-11-23 | Sean Forde | Catheter extension control |
US10130409B2 (en) | 2013-11-05 | 2018-11-20 | Myoscience, Inc. | Secure cryosurgical treatment system |
US20200281638A1 (en) * | 2019-03-08 | 2020-09-10 | Georg Daniel Andreas Nollert | Catheter system for cryoablation, in particular cryoablation of the gastric wall |
CN112022332A (zh) * | 2020-09-03 | 2020-12-04 | 至善介入消融技术研究院(南京)有限公司 | 一种消融针 |
US10888366B2 (en) | 2013-03-15 | 2021-01-12 | Pacira Cryotech, Inc. | Cryogenic blunt dissection methods and devices |
US11134998B2 (en) | 2017-11-15 | 2021-10-05 | Pacira Cryotech, Inc. | Integrated cold therapy and electrical stimulation systems for locating and treating nerves and associated methods |
CN113842206A (zh) * | 2021-11-30 | 2021-12-28 | 海杰亚(北京)医疗器械有限公司 | 用于冷冻消融手术设备的酒精回收方法、装置及系统 |
US11311327B2 (en) | 2016-05-13 | 2022-04-26 | Pacira Cryotech, Inc. | Methods and systems for locating and treating nerves with cold therapy |
Families Citing this family (30)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP4608652B2 (ja) * | 2004-11-05 | 2011-01-12 | 国立大学法人東北大学 | 冷凍手術装置およびその温度制御方法 |
US7425211B2 (en) * | 2006-08-03 | 2008-09-16 | Arbel Medical Ltd. | Cryogenic probe for treating enlarged volume of tissue |
US9089316B2 (en) * | 2009-11-02 | 2015-07-28 | Endocare, Inc. | Cryogenic medical system |
US10695126B2 (en) | 2008-10-06 | 2020-06-30 | Santa Anna Tech Llc | Catheter with a double balloon structure to generate and apply a heated ablative zone to tissue |
KR101048484B1 (ko) | 2009-07-21 | 2011-07-12 | 화인엠이씨주식회사 | 피부 진피조직 응고장치 |
JP5836964B2 (ja) | 2009-11-05 | 2015-12-24 | ニンバス・コンセプツ・エルエルシー | 脊椎高周波神経切断術のための方法およびシステム |
US20110288540A1 (en) | 2010-05-21 | 2011-11-24 | Nimbus Concepts, Llc | Systems and methods for tissue ablation |
CN107349009B (zh) | 2010-08-05 | 2020-06-26 | 美敦力Af卢森堡有限责任公司 | 用于肾神经调制的低温消融装置、系统及方法 |
US20120158104A1 (en) | 2010-10-26 | 2012-06-21 | Medtronic Ardian Luxembourg S.A.R.L. | Neuromodulation cryotherapeutic devices and associated systems and methods |
US9060754B2 (en) | 2010-10-26 | 2015-06-23 | Medtronic Ardian Luxembourg S.A.R.L. | Neuromodulation cryotherapeutic devices and associated systems and methods |
WO2012148969A2 (en) | 2011-04-25 | 2012-11-01 | Brian Kelly | Apparatus and methods related to constrained deployment of cryogenic balloons for limited cryogenic ablation of vessel walls |
US9492113B2 (en) | 2011-07-15 | 2016-11-15 | Boston Scientific Scimed, Inc. | Systems and methods for monitoring organ activity |
US9283110B2 (en) * | 2011-09-20 | 2016-03-15 | Zoll Circulation, Inc. | Patient temperature control catheter with outer sleeve cooled by inner sleeve |
US9265459B2 (en) * | 2011-10-07 | 2016-02-23 | Boston Scientific Scimed, Inc. | Methods and systems for detection and thermal treatment of lower urinary tract conditions |
US20130090638A1 (en) * | 2011-10-07 | 2013-04-11 | Galil Medical Inc. | Flexible Cryoneedle Apparatus and Method |
US9561346B2 (en) * | 2012-01-11 | 2017-02-07 | Uc-Care Ltd. | Catheterization apparatus and methods thereof |
US20150088113A1 (en) | 2012-04-27 | 2015-03-26 | Medtronic Ardian Luxembourg S.A.R.L. | Cryotherapeutic devices for renal neuromodulation and associated systems and methods |
US9241752B2 (en) | 2012-04-27 | 2016-01-26 | Medtronic Ardian Luxembourg S.A.R.L. | Shafts with pressure relief in cryotherapeutic catheters and associated devices, systems, and methods |
US9095321B2 (en) | 2012-11-21 | 2015-08-04 | Medtronic Ardian Luxembourg S.A.R.L. | Cryotherapeutic devices having integral multi-helical balloons and methods of making the same |
US9017317B2 (en) | 2012-12-06 | 2015-04-28 | Medtronic Ardian Luxembourg S.A.R.L. | Refrigerant supply system for cryotherapy including refrigerant recompression and associated devices, systems, and methods |
US9433464B2 (en) | 2013-03-14 | 2016-09-06 | Biosense Webster (Israel) Ltd. | Catheter with needles for ablating tissue layers in vessel |
US10492842B2 (en) | 2014-03-07 | 2019-12-03 | Medtronic Ardian Luxembourg S.A.R.L. | Monitoring and controlling internally administered cryotherapy |
PL3146924T3 (pl) | 2015-09-24 | 2023-03-20 | Medinice S.A. | Krioaplikator do mało-inwazyjnej ablacji kardiochirurgicznej |
US11331140B2 (en) | 2016-05-19 | 2022-05-17 | Aqua Heart, Inc. | Heated vapor ablation systems and methods for treating cardiac conditions |
EP3606481A4 (en) * | 2017-04-07 | 2020-12-23 | Palmera Medical, Inc. | THERAPEUTIC ORGAN COOLING |
CN109199570B (zh) * | 2017-06-29 | 2020-11-17 | 四川锦江电子科技有限公司 | 一种极间冷冻消融导管 |
WO2020005816A1 (en) * | 2018-06-29 | 2020-01-02 | Miraki Innovation Think Tank, Llc | Miniaturized intra-body controllable cold therapy medical devices and methods |
CN109171948B (zh) * | 2018-10-26 | 2021-01-19 | 丽水市中心医院 | 冷冻消融针及应用该冷冻消融针的系统 |
GB201902657D0 (en) * | 2019-02-27 | 2019-04-10 | He Carbon Supercap Ltd | He supercap |
WO2024095824A1 (ja) * | 2022-11-02 | 2024-05-10 | 株式会社カネカ | クライオアブレーションカテーテルおよびクライオアブレーションカテーテルシステム |
Citations (34)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3298371A (en) * | 1965-02-11 | 1967-01-17 | Arnold S J Lee | Freezing probe for the treatment of tissue, especially in neurosurgery |
US3782386A (en) * | 1972-05-08 | 1974-01-01 | Dynatech Corp | Cryosurgical apparatus |
US3913581A (en) * | 1972-06-02 | 1975-10-21 | Spembly Ltd | Cryogenic apparatus |
US4015606A (en) * | 1975-09-09 | 1977-04-05 | Dynatech Corporation | Method and means for controlling the freeze zone of a cryosurgical probe |
US4207897A (en) * | 1976-07-21 | 1980-06-17 | Spembly Limited | Cryosurgical probe |
US4924679A (en) * | 1989-10-02 | 1990-05-15 | Zwick Energy Research Organization, Inc. | Apparatus and method for evacuating an insulated cryogenic hose |
US5078713A (en) * | 1988-12-01 | 1992-01-07 | Spembly Medical Limited | Cryosurgical probe |
US5147355A (en) * | 1988-09-23 | 1992-09-15 | Brigham And Womens Hospital | Cryoablation catheter and method of performing cryoablation |
US5254116A (en) * | 1991-09-06 | 1993-10-19 | Cryomedical Sciences, Inc. | Cryosurgical instrument with vent holes and method using same |
US5281215A (en) * | 1992-04-16 | 1994-01-25 | Implemed, Inc. | Cryogenic catheter |
US5281213A (en) * | 1992-04-16 | 1994-01-25 | Implemed, Inc. | Catheter for ice mapping and ablation |
US5334181A (en) * | 1990-09-26 | 1994-08-02 | Cryomedical Sciences, Inc. | Cryosurgical system for destroying tumors by freezing |
US5403309A (en) * | 1992-07-31 | 1995-04-04 | Spembly Medical Limited | Cryosurgical ablation |
US5403311A (en) * | 1993-03-29 | 1995-04-04 | Boston Scientific Corporation | Electro-coagulation and ablation and other electrotherapeutic treatments of body tissue |
US5425582A (en) * | 1992-01-31 | 1995-06-20 | Hochiki Kabushiki Kaisha | Thermal detector and method of producing the same |
US5501681A (en) * | 1993-11-12 | 1996-03-26 | Neuwirth; Robert S. | Intrauterine cryoablation cauterizing apparatus and method |
US5624392A (en) * | 1990-05-11 | 1997-04-29 | Saab; Mark A. | Heat transfer catheters and methods of making and using same |
US5688267A (en) * | 1995-05-01 | 1997-11-18 | Ep Technologies, Inc. | Systems and methods for sensing multiple temperature conditions during tissue ablation |
US5716353A (en) * | 1996-05-03 | 1998-02-10 | Urds, Corp. | Cryosurgical instrument |
US5733280A (en) * | 1995-11-15 | 1998-03-31 | Avitall; Boaz | Cryogenic epicardial mapping and ablation |
US5741248A (en) * | 1995-06-07 | 1998-04-21 | Temple University-Of The Commonwealth System Of Higher Education | Fluorochemical liquid augmented cryosurgery |
US5807391A (en) * | 1993-10-26 | 1998-09-15 | Cordis Corporation | Cryo-ablation catheter |
US5853368A (en) * | 1996-12-23 | 1998-12-29 | Hewlett-Packard Company | Ultrasound imaging catheter having an independently-controllable treatment structure |
US5885276A (en) * | 1997-12-02 | 1999-03-23 | Galil Medical Ltd. | Method and device for transmyocardial cryo revascularization |
US5893848A (en) * | 1996-10-24 | 1999-04-13 | Plc Medical Systems, Inc. | Gauging system for monitoring channel depth in percutaneous endocardial revascularization |
US5951546A (en) * | 1994-12-13 | 1999-09-14 | Lorentzen; Torben | Electrosurgical instrument for tissue ablation, an apparatus, and a method for providing a lesion in damaged and diseased tissue from a mammal |
US6074412A (en) * | 1996-07-23 | 2000-06-13 | Endocare, Inc. | Cryoprobe |
US6164283A (en) * | 1997-07-08 | 2000-12-26 | The Regents Of The University Of California | Device and method for forming a circumferential conduction block in a pulmonary vein |
US6355029B1 (en) * | 1997-12-02 | 2002-03-12 | Cryovascular Systems, Inc. | Apparatus and method for cryogenic inhibition of hyperplasia |
US20020040220A1 (en) * | 2000-07-31 | 2002-04-04 | Roni Zvuloni | Planning and facilitation systems and methods for cryosurgery |
US6451012B2 (en) * | 1996-12-26 | 2002-09-17 | Cryogen, Inc. | Cryosurgical method for endometrial ablation |
US6506189B1 (en) * | 1995-05-04 | 2003-01-14 | Sherwood Services Ag | Cool-tip electrode thermosurgery system |
US20030029462A1 (en) * | 1996-10-22 | 2003-02-13 | Epicor, Inc. | Device and method for forming a lesion |
US6527767B2 (en) * | 1998-05-20 | 2003-03-04 | New England Medical Center | Cardiac ablation system and method for treatment of cardiac arrhythmias and transmyocardial revascularization |
Family Cites Families (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3664344A (en) * | 1970-09-15 | 1972-05-23 | Brymill Corp | Tyned cryosurgical probe |
US5423807A (en) * | 1992-04-16 | 1995-06-13 | Implemed, Inc. | Cryogenic mapping and ablation catheter |
WO1994010922A1 (en) * | 1992-11-13 | 1994-05-26 | Ep Technologies, Inc. | Cardial ablation systems using temperature monitoring |
GB2283678B (en) * | 1993-11-09 | 1998-06-03 | Spembly Medical Ltd | Cryosurgical catheter probe |
DE19621099C2 (de) * | 1996-05-24 | 1999-05-20 | Sulzer Osypka Gmbh | Vorrichtung mit einem Katheter und einer von der Innenseite in die Herzwand einstechbaren Nadel als Hochfrequenzelektrode |
US5899898A (en) * | 1997-02-27 | 1999-05-04 | Cryocath Technologies Inc. | Cryosurgical linear ablation |
US5868735A (en) * | 1997-03-06 | 1999-02-09 | Scimed Life Systems, Inc. | Cryoplasty device and method |
US6012457A (en) * | 1997-07-08 | 2000-01-11 | The Regents Of The University Of California | Device and method for forming a circumferential conduction block in a pulmonary vein |
US6063082A (en) * | 1997-11-04 | 2000-05-16 | Scimed Life Systems, Inc. | Percutaneous myocardial revascularization basket delivery system and radiofrequency therapeutic device |
US6056743A (en) * | 1997-11-04 | 2000-05-02 | Scimed Life Systems, Inc. | Percutaneous myocardial revascularization device and method |
US6142991A (en) * | 1998-03-31 | 2000-11-07 | Galil Medical, Ltd. | High resolution cryosurgical method and apparatus |
US6106518A (en) * | 1998-04-09 | 2000-08-22 | Cryocath Technologies, Inc. | Variable geometry tip for a cryosurgical ablation device |
US6468268B1 (en) * | 1999-01-25 | 2002-10-22 | Cryocath Technologies Inc. | Cryogenic catheter system |
US6565556B1 (en) * | 1999-02-12 | 2003-05-20 | Nikolai Korpan | Device for carrying out cryosurgical interventions, especially for treating tumors |
US7147633B2 (en) * | 1999-06-02 | 2006-12-12 | Boston Scientific Scimed, Inc. | Method and apparatus for treatment of atrial fibrillation |
US6237355B1 (en) * | 1999-06-25 | 2001-05-29 | Cryogen, Inc. | Precooled cryogenic ablation system |
US6283959B1 (en) * | 1999-08-23 | 2001-09-04 | Cyrocath Technologies, Inc. | Endovascular cryotreatment catheter |
WO2001037919A2 (en) * | 1999-11-12 | 2001-05-31 | Cryocath Technologies, Inc. | Cryomedical device for promoting angiogenesis |
US6706037B2 (en) * | 2000-10-24 | 2004-03-16 | Galil Medical Ltd. | Multiple cryoprobe apparatus and method |
US7479139B2 (en) * | 2002-01-04 | 2009-01-20 | Galil Medical Ltd. | Apparatus and method for protecting tissues during cryoablation |
US20040204705A1 (en) | 2003-04-10 | 2004-10-14 | Scimed Life Systems, Inc. | Cryotreatment devices and methods of forming conduction blocks |
JP4767761B2 (ja) * | 2006-06-05 | 2011-09-07 | 直久 矢作 | 高周波処置具 |
-
2003
- 2003-04-10 US US10/411,601 patent/US20040204705A1/en not_active Abandoned
-
2004
- 2004-04-08 JP JP2006509805A patent/JP4653734B2/ja not_active Expired - Fee Related
- 2004-04-08 EP EP04759260.5A patent/EP1610702B1/en not_active Expired - Lifetime
- 2004-04-08 CA CA002521714A patent/CA2521714A1/en not_active Abandoned
- 2004-04-08 WO PCT/US2004/010806 patent/WO2004091416A1/en active Application Filing
-
2009
- 2009-06-16 US US12/485,697 patent/US8048066B2/en not_active Expired - Fee Related
-
2011
- 2011-10-04 US US13/252,817 patent/US8585689B2/en not_active Expired - Fee Related
-
2013
- 2013-11-19 US US14/084,257 patent/US9033967B2/en not_active Expired - Lifetime
-
2015
- 2015-05-13 US US14/711,232 patent/US9339322B2/en not_active Expired - Fee Related
-
2016
- 2016-04-19 US US15/132,934 patent/US9750556B2/en not_active Expired - Lifetime
Patent Citations (34)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3298371A (en) * | 1965-02-11 | 1967-01-17 | Arnold S J Lee | Freezing probe for the treatment of tissue, especially in neurosurgery |
US3782386A (en) * | 1972-05-08 | 1974-01-01 | Dynatech Corp | Cryosurgical apparatus |
US3913581A (en) * | 1972-06-02 | 1975-10-21 | Spembly Ltd | Cryogenic apparatus |
US4015606A (en) * | 1975-09-09 | 1977-04-05 | Dynatech Corporation | Method and means for controlling the freeze zone of a cryosurgical probe |
US4207897A (en) * | 1976-07-21 | 1980-06-17 | Spembly Limited | Cryosurgical probe |
US5147355A (en) * | 1988-09-23 | 1992-09-15 | Brigham And Womens Hospital | Cryoablation catheter and method of performing cryoablation |
US5078713A (en) * | 1988-12-01 | 1992-01-07 | Spembly Medical Limited | Cryosurgical probe |
US4924679A (en) * | 1989-10-02 | 1990-05-15 | Zwick Energy Research Organization, Inc. | Apparatus and method for evacuating an insulated cryogenic hose |
US5624392A (en) * | 1990-05-11 | 1997-04-29 | Saab; Mark A. | Heat transfer catheters and methods of making and using same |
US5334181A (en) * | 1990-09-26 | 1994-08-02 | Cryomedical Sciences, Inc. | Cryosurgical system for destroying tumors by freezing |
US5254116A (en) * | 1991-09-06 | 1993-10-19 | Cryomedical Sciences, Inc. | Cryosurgical instrument with vent holes and method using same |
US5425582A (en) * | 1992-01-31 | 1995-06-20 | Hochiki Kabushiki Kaisha | Thermal detector and method of producing the same |
US5281215A (en) * | 1992-04-16 | 1994-01-25 | Implemed, Inc. | Cryogenic catheter |
US5281213A (en) * | 1992-04-16 | 1994-01-25 | Implemed, Inc. | Catheter for ice mapping and ablation |
US5403309A (en) * | 1992-07-31 | 1995-04-04 | Spembly Medical Limited | Cryosurgical ablation |
US5403311A (en) * | 1993-03-29 | 1995-04-04 | Boston Scientific Corporation | Electro-coagulation and ablation and other electrotherapeutic treatments of body tissue |
US5807391A (en) * | 1993-10-26 | 1998-09-15 | Cordis Corporation | Cryo-ablation catheter |
US5501681A (en) * | 1993-11-12 | 1996-03-26 | Neuwirth; Robert S. | Intrauterine cryoablation cauterizing apparatus and method |
US5951546A (en) * | 1994-12-13 | 1999-09-14 | Lorentzen; Torben | Electrosurgical instrument for tissue ablation, an apparatus, and a method for providing a lesion in damaged and diseased tissue from a mammal |
US5688267A (en) * | 1995-05-01 | 1997-11-18 | Ep Technologies, Inc. | Systems and methods for sensing multiple temperature conditions during tissue ablation |
US6506189B1 (en) * | 1995-05-04 | 2003-01-14 | Sherwood Services Ag | Cool-tip electrode thermosurgery system |
US5741248A (en) * | 1995-06-07 | 1998-04-21 | Temple University-Of The Commonwealth System Of Higher Education | Fluorochemical liquid augmented cryosurgery |
US5733280A (en) * | 1995-11-15 | 1998-03-31 | Avitall; Boaz | Cryogenic epicardial mapping and ablation |
US5716353A (en) * | 1996-05-03 | 1998-02-10 | Urds, Corp. | Cryosurgical instrument |
US6074412A (en) * | 1996-07-23 | 2000-06-13 | Endocare, Inc. | Cryoprobe |
US20030029462A1 (en) * | 1996-10-22 | 2003-02-13 | Epicor, Inc. | Device and method for forming a lesion |
US5893848A (en) * | 1996-10-24 | 1999-04-13 | Plc Medical Systems, Inc. | Gauging system for monitoring channel depth in percutaneous endocardial revascularization |
US5853368A (en) * | 1996-12-23 | 1998-12-29 | Hewlett-Packard Company | Ultrasound imaging catheter having an independently-controllable treatment structure |
US6451012B2 (en) * | 1996-12-26 | 2002-09-17 | Cryogen, Inc. | Cryosurgical method for endometrial ablation |
US6164283A (en) * | 1997-07-08 | 2000-12-26 | The Regents Of The University Of California | Device and method for forming a circumferential conduction block in a pulmonary vein |
US6355029B1 (en) * | 1997-12-02 | 2002-03-12 | Cryovascular Systems, Inc. | Apparatus and method for cryogenic inhibition of hyperplasia |
US5885276A (en) * | 1997-12-02 | 1999-03-23 | Galil Medical Ltd. | Method and device for transmyocardial cryo revascularization |
US6527767B2 (en) * | 1998-05-20 | 2003-03-04 | New England Medical Center | Cardiac ablation system and method for treatment of cardiac arrhythmias and transmyocardial revascularization |
US20020040220A1 (en) * | 2000-07-31 | 2002-04-04 | Roni Zvuloni | Planning and facilitation systems and methods for cryosurgery |
Cited By (75)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20070167938A1 (en) * | 2000-10-24 | 2007-07-19 | Galil Medical Ltd. | Multiple cryoprobe delivery apparatus |
US20070088247A1 (en) * | 2000-10-24 | 2007-04-19 | Galil Medical Ltd. | Apparatus and method for thermal ablation of uterine fibroids |
US20080045934A1 (en) * | 2000-10-24 | 2008-02-21 | Galil Medical Ltd. | Device and method for coordinated insertion of a plurality of cryoprobes |
US8066697B2 (en) * | 2000-10-24 | 2011-11-29 | Galil Medical Ltd. | Multiple cryoprobe delivery apparatus |
US20080300586A1 (en) * | 2000-10-24 | 2008-12-04 | Galil Medical Ltd. | Apparatus and method for compressing a gas, and cryosurgery system and method utilizing same |
US20080051774A1 (en) * | 2001-05-21 | 2008-02-28 | Galil Medical Ltd. | Device and method for coordinated insertion of a plurality of cryoprobes |
US20080051776A1 (en) * | 2001-05-21 | 2008-02-28 | Galil Medical Ltd. | Thin uninsulated cryoprobe and insulating probe introducer |
US9750556B2 (en) | 2003-04-10 | 2017-09-05 | Boston Scientific Scimed, Inc. | Cryotreatment devices and methods of forming conduction blocks |
US9339322B2 (en) | 2003-04-10 | 2016-05-17 | Boston Scientific Scimed Inc. | Cryotreatment devices and methods of forming conduction blocks |
US8007847B2 (en) | 2004-01-13 | 2011-08-30 | Eytan Biderman | Feeding formula appliance |
US20090005769A1 (en) * | 2004-07-27 | 2009-01-01 | Plymouth Hospitals Nhs Trust | Catheter, Apparatus for Creating a Linear Ablation and a Method of Ablating Tissue |
EP1786345B1 (en) * | 2004-07-27 | 2013-04-24 | Plymouth Hospitals NHS Trust | Apparatus for creating a linear ablation |
US9370391B2 (en) * | 2004-07-27 | 2016-06-21 | Plymouth Hospitals Nhs Trust | Catheter, apparatus for creating a linear ablation and a method of ablating tissue |
US20090171334A1 (en) * | 2005-05-20 | 2009-07-02 | Myoscience, Inc. | Subdermal cryogenic remodeling of muscles, nerves, connective tissue, and/or adipose tissue (fat) |
US11350979B2 (en) | 2005-05-20 | 2022-06-07 | Pacira Cryotech, Inc. | Subdermal cryogenic remodeling of muscles, nerves, connective tissue, and/or adipose tissue (fat) |
US10363080B2 (en) | 2005-05-20 | 2019-07-30 | Pacira Cryotech, Inc. | Subdermal cryogenic remodeling of muscles, nerves, connective tissue, and/or adipose tissue (fat) |
US7713266B2 (en) | 2005-05-20 | 2010-05-11 | Myoscience, Inc. | Subdermal cryogenic remodeling of muscles, nerves, connective tissue, and/or adipose tissue (fat) |
US9072498B2 (en) | 2005-05-20 | 2015-07-07 | Myoscience, Inc. | Subdermal cryogenic remodeling of muscles, nerves, connective tissue, and/or adipose tissue (fat) |
US7850683B2 (en) | 2005-05-20 | 2010-12-14 | Myoscience, Inc. | Subdermal cryogenic remodeling of muscles, nerves, connective tissue, and/or adipose tissue (fat) |
US7862558B2 (en) | 2005-05-20 | 2011-01-04 | Myoscience, Inc. | Subdermal cryogenic remodeling of muscles, nerves, connective tissue, and/or adipose tissue (fat) |
US7998137B2 (en) | 2005-05-20 | 2011-08-16 | Myoscience, Inc. | Subdermal cryogenic remodeling of muscles, nerves, connective tissue, and/or adipose tissue (fat) |
US9345526B2 (en) | 2005-05-20 | 2016-05-24 | Myoscience, Inc. | Subdermal cryogenic remodeling of muscles, nerves, connective tissue, and/or adipose tissue (fat) |
US11963706B2 (en) | 2005-05-20 | 2024-04-23 | Pacira Cryotech, Inc. | Subdermal cryogenic remodeling of muscles, nerves, connective tissue, and/or adipose tissue (fat) |
US20080051775A1 (en) * | 2005-11-23 | 2008-02-28 | Evans David K | Multi-modal analgesia delivery system ("MADS") |
US20090292279A1 (en) * | 2006-01-26 | 2009-11-26 | Galil Medical Ltd. | Device and Method for Coordinated Insertion of a Plurality of Cryoprobes |
WO2007135431A2 (en) * | 2006-05-24 | 2007-11-29 | Emcision Limited | Vessel sealing device and methods |
US20100268217A1 (en) * | 2006-05-24 | 2010-10-21 | Emcision Limited | Vessel sealing device and methods |
WO2007135431A3 (en) * | 2006-05-24 | 2008-01-10 | Emcision Ltd | Vessel sealing device and methods |
US9254162B2 (en) | 2006-12-21 | 2016-02-09 | Myoscience, Inc. | Dermal and transdermal cryogenic microprobe systems |
US10939947B2 (en) | 2006-12-21 | 2021-03-09 | Pacira Cryotech, Inc. | Dermal and transdermal cryogenic microprobe systems |
US8409185B2 (en) | 2007-02-16 | 2013-04-02 | Myoscience, Inc. | Replaceable and/or easily removable needle systems for dermal and transdermal cryogenic remodeling |
US9113855B2 (en) | 2007-02-16 | 2015-08-25 | Myoscience, Inc. | Replaceable and/or easily removable needle systems for dermal and transdermal cryogenic remodeling |
WO2008142686A2 (en) * | 2007-05-21 | 2008-11-27 | Uc-Care Ltd. | Ablation probe |
WO2008142686A3 (en) * | 2007-05-21 | 2009-05-07 | Uc Care Ltd | Ablation probe |
US11672694B2 (en) | 2007-11-14 | 2023-06-13 | Pacira Cryotech, Inc. | Pain management using cryogenic remodeling |
US10869779B2 (en) | 2007-11-14 | 2020-12-22 | Pacira Cryotech, Inc. | Pain management using cryogenic remodeling |
US9101346B2 (en) | 2007-11-14 | 2015-08-11 | Myoscience, Inc. | Pain management using cryogenic remodeling |
US8715275B2 (en) | 2007-11-14 | 2014-05-06 | Myoscience, Inc. | Pain management using cryogenic remodeling |
US8298216B2 (en) | 2007-11-14 | 2012-10-30 | Myoscience, Inc. | Pain management using cryogenic remodeling |
US10864112B2 (en) | 2007-11-14 | 2020-12-15 | Pacira Cryotech, Inc. | Pain management using cryogenic remodeling |
US9907693B2 (en) | 2007-11-14 | 2018-03-06 | Myoscience, Inc. | Pain management using cryogenic remodeling |
US20090299420A1 (en) * | 2008-06-02 | 2009-12-03 | Shuros Allan C | Method and apparatus for cryotherapy and pacing preconditioning |
US9066712B2 (en) | 2008-12-22 | 2015-06-30 | Myoscience, Inc. | Integrated cryosurgical system with refrigerant and electrical power source |
US9314290B2 (en) * | 2012-01-13 | 2016-04-19 | Myoscience, Inc. | Cryogenic needle with freeze zone regulation |
US20160183998A1 (en) * | 2012-01-13 | 2016-06-30 | Myoscience, Inc. | Cryogenic Needle With Freeze Zone Regulation |
US20130184696A1 (en) * | 2012-01-13 | 2013-07-18 | Myoscience, Inc. | Cryogenic Needle with Freeze Zone Regulation |
US11857239B2 (en) | 2012-01-13 | 2024-01-02 | Pacira Cryotech, Inc. | Cryogenic needle with freeze zone regulation |
US9155584B2 (en) | 2012-01-13 | 2015-10-13 | Myoscience, Inc. | Cryogenic probe filtration system |
US9241753B2 (en) | 2012-01-13 | 2016-01-26 | Myoscience, Inc. | Skin protection for subdermal cryogenic remodeling for cosmetic and other treatments |
US10188444B2 (en) | 2012-01-13 | 2019-01-29 | Myoscience, Inc. | Skin protection for subdermal cryogenic remodeling for cosmetic and other treatments |
US10213244B2 (en) * | 2012-01-13 | 2019-02-26 | Myoscience, Inc. | Cryogenic needle with freeze zone regulation |
US9017318B2 (en) | 2012-01-20 | 2015-04-28 | Myoscience, Inc. | Cryogenic probe system and method |
US11253393B2 (en) | 2013-03-15 | 2022-02-22 | Pacira Cryotech, Inc. | Methods, systems, and devices for treating neuromas, fibromas, nerve entrapment, and/or pain associated therewith |
US11642241B2 (en) | 2013-03-15 | 2023-05-09 | Pacira Cryotech, Inc. | Cryogenic enhancement of joint function, alleviation of joint stiffness and/or alleviation of pain associated with osteoarthritis |
US10596030B2 (en) | 2013-03-15 | 2020-03-24 | Pacira Cryotech, Inc. | Cryogenic enhancement of joint function, alleviation of joint stiffness and/or alleviation of pain associated with osteoarthritis |
US9668800B2 (en) | 2013-03-15 | 2017-06-06 | Myoscience, Inc. | Methods and systems for treatment of spasticity |
US11865038B2 (en) | 2013-03-15 | 2024-01-09 | Pacira Cryotech, Inc. | Methods, systems, and devices for treating nerve spasticity |
US10314739B2 (en) | 2013-03-15 | 2019-06-11 | Myoscience, Inc. | Methods and devices for pain management |
US10016229B2 (en) | 2013-03-15 | 2018-07-10 | Myoscience, Inc. | Methods and systems for treatment of occipital neuralgia |
US9295512B2 (en) | 2013-03-15 | 2016-03-29 | Myoscience, Inc. | Methods and devices for pain management |
US10888366B2 (en) | 2013-03-15 | 2021-01-12 | Pacira Cryotech, Inc. | Cryogenic blunt dissection methods and devices |
US10085789B2 (en) | 2013-03-15 | 2018-10-02 | Myoscience, Inc. | Methods and systems for treatment of occipital neuralgia |
US9610112B2 (en) | 2013-03-15 | 2017-04-04 | Myoscience, Inc. | Cryogenic enhancement of joint function, alleviation of joint stiffness and/or alleviation of pain associated with osteoarthritis |
US11134999B2 (en) | 2013-03-15 | 2021-10-05 | Pacira Cryotech, Inc. | Methods and systems for treatment of occipital neuralgia |
US10085881B2 (en) | 2013-03-15 | 2018-10-02 | Myoscience, Inc. | Methods, systems, and devices for treating neuromas, fibromas, nerve entrapment, and/or pain associated therewith |
US10130409B2 (en) | 2013-11-05 | 2018-11-20 | Myoscience, Inc. | Secure cryosurgical treatment system |
US11690661B2 (en) | 2013-11-05 | 2023-07-04 | Pacira Cryotech, Inc. | Secure cryosurgical treatment system |
US10864033B2 (en) | 2013-11-05 | 2020-12-15 | Pacira Cryotech, Inc. | Secure cryosurgical treatment system |
US11311327B2 (en) | 2016-05-13 | 2022-04-26 | Pacira Cryotech, Inc. | Methods and systems for locating and treating nerves with cold therapy |
US20170333104A1 (en) * | 2016-05-19 | 2017-11-23 | Sean Forde | Catheter extension control |
US11871977B2 (en) * | 2016-05-19 | 2024-01-16 | Csa Medical, Inc. | Catheter extension control |
US11134998B2 (en) | 2017-11-15 | 2021-10-05 | Pacira Cryotech, Inc. | Integrated cold therapy and electrical stimulation systems for locating and treating nerves and associated methods |
US20200281638A1 (en) * | 2019-03-08 | 2020-09-10 | Georg Daniel Andreas Nollert | Catheter system for cryoablation, in particular cryoablation of the gastric wall |
CN112022332A (zh) * | 2020-09-03 | 2020-12-04 | 至善介入消融技术研究院(南京)有限公司 | 一种消融针 |
CN113842206A (zh) * | 2021-11-30 | 2021-12-28 | 海杰亚(北京)医疗器械有限公司 | 用于冷冻消融手术设备的酒精回收方法、装置及系统 |
Also Published As
Publication number | Publication date |
---|---|
US8585689B2 (en) | 2013-11-19 |
CA2521714A1 (en) | 2004-10-28 |
US9750556B2 (en) | 2017-09-05 |
JP4653734B2 (ja) | 2011-03-16 |
US20160228174A1 (en) | 2016-08-11 |
US20150238244A1 (en) | 2015-08-27 |
JP2006524105A (ja) | 2006-10-26 |
US8048066B2 (en) | 2011-11-01 |
EP1610702B1 (en) | 2016-01-13 |
US9033967B2 (en) | 2015-05-19 |
US20140066914A1 (en) | 2014-03-06 |
US20090299358A1 (en) | 2009-12-03 |
US20120022513A1 (en) | 2012-01-26 |
EP1610702A1 (en) | 2006-01-04 |
US9339322B2 (en) | 2016-05-17 |
WO2004091416A1 (en) | 2004-10-28 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
US9750556B2 (en) | Cryotreatment devices and methods of forming conduction blocks | |
US6755822B2 (en) | Device and method for the creation of a circumferential cryogenic lesion in a pulmonary vein | |
JP4523586B2 (ja) | 挿入領域で隔離された領域を有する治療装置 | |
US5147355A (en) | Cryoablation catheter and method of performing cryoablation | |
US20060253183A1 (en) | Intramural needle-tipped surgical device | |
US20040243118A1 (en) | Device and method for positioning a catheter tip for creating a cryogenic lesion | |
JP2005052630A (ja) | 凍結融解壊死療法システムおよび方法 | |
AU2004284941A1 (en) | Catheter and method for ablation of atrial tissue | |
JP2011206569A (ja) | カテーテル、線状切断を行うための装置および組織切断方法 | |
Lewis et al. | Catheter application of cryogenic temperatures inside the heart | |
AU2003275771A1 (en) | An intramural needle-tipped surgical device |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
AS | Assignment |
Owner name: SCIMED LIFE SYSTEMS, INC., MINNESOTA Free format text: ASSIGNMENT OF ASSIGNORS INTEREST;ASSIGNOR:LAFONTAINE, DANIEL M.;REEL/FRAME:013982/0358 Effective date: 20030408 |
|
AS | Assignment |
Owner name: BOSTON SCIENTIFIC SCIMED, INC., MINNESOTA Free format text: CHANGE OF NAME;ASSIGNOR:SCIMED LIFE SYSTEMS, INC.;REEL/FRAME:018505/0868 Effective date: 20050101 Owner name: BOSTON SCIENTIFIC SCIMED, INC.,MINNESOTA Free format text: CHANGE OF NAME;ASSIGNOR:SCIMED LIFE SYSTEMS, INC.;REEL/FRAME:018505/0868 Effective date: 20050101 |
|
STCB | Information on status: application discontinuation |
Free format text: ABANDONED -- FAILURE TO RESPOND TO AN OFFICE ACTION |