US20030106902A1 - Storage and delivery containers for imaging and spectroscopic agents - Google Patents
Storage and delivery containers for imaging and spectroscopic agents Download PDFInfo
- Publication number
- US20030106902A1 US20030106902A1 US10/279,042 US27904202A US2003106902A1 US 20030106902 A1 US20030106902 A1 US 20030106902A1 US 27904202 A US27904202 A US 27904202A US 2003106902 A1 US2003106902 A1 US 2003106902A1
- Authority
- US
- United States
- Prior art keywords
- container
- gas
- sheet
- fitting
- cavity
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- 238000003860 storage Methods 0.000 title claims description 5
- 238000003384 imaging method Methods 0.000 title description 4
- 238000007789 sealing Methods 0.000 claims abstract description 18
- 230000004888 barrier function Effects 0.000 claims abstract description 12
- 238000000034 method Methods 0.000 claims abstract description 10
- 239000000203 mixture Substances 0.000 claims description 14
- 239000012530 fluid Substances 0.000 claims description 11
- 238000004891 communication Methods 0.000 claims description 8
- 238000010926 purge Methods 0.000 claims description 8
- 238000005299 abrasion Methods 0.000 claims description 2
- 239000010410 layer Substances 0.000 claims 8
- 239000013047 polymeric layer Substances 0.000 claims 1
- 239000007789 gas Substances 0.000 description 60
- 239000000463 material Substances 0.000 description 6
- 238000000605 extraction Methods 0.000 description 5
- XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 description 4
- 229910052782 aluminium Inorganic materials 0.000 description 4
- 239000004698 Polyethylene Substances 0.000 description 3
- 230000009977 dual effect Effects 0.000 description 3
- 230000010287 polarization Effects 0.000 description 3
- 229920000728 polyester Polymers 0.000 description 3
- -1 polyethylene Polymers 0.000 description 3
- 229920000573 polyethylene Polymers 0.000 description 3
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 2
- 239000001301 oxygen Substances 0.000 description 2
- 229910052760 oxygen Inorganic materials 0.000 description 2
- 239000000523 sample Substances 0.000 description 2
- 239000011800 void material Substances 0.000 description 2
- 229920001328 Polyvinylidene chloride Polymers 0.000 description 1
- 239000012080 ambient air Substances 0.000 description 1
- 230000000903 blocking effect Effects 0.000 description 1
- 238000010276 construction Methods 0.000 description 1
- 239000012611 container material Substances 0.000 description 1
- 239000000356 contaminant Substances 0.000 description 1
- 238000009826 distribution Methods 0.000 description 1
- 239000011888 foil Substances 0.000 description 1
- 238000011503 in vivo imaging Methods 0.000 description 1
- 238000002595 magnetic resonance imaging Methods 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 239000004033 plastic Substances 0.000 description 1
- 229920003023 plastic Polymers 0.000 description 1
- 239000005033 polyvinylidene chloride Substances 0.000 description 1
- 238000009877 rendering Methods 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 238000004611 spectroscopical analysis Methods 0.000 description 1
- 229910001220 stainless steel Inorganic materials 0.000 description 1
- 239000010935 stainless steel Substances 0.000 description 1
- 239000002699 waste material Substances 0.000 description 1
- 238000003466 welding Methods 0.000 description 1
Images
Classifications
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- F17C3/00—Vessels not under pressure
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- F17C2201/00—Vessel construction, in particular geometry, arrangement or size
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- F17C2205/00—Vessel construction, in particular mounting arrangements, attachments or identifications means
- F17C2205/01—Mounting arrangements
- F17C2205/0123—Mounting arrangements characterised by number of vessels
- F17C2205/013—Two or more vessels
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- F17C2205/00—Vessel construction, in particular mounting arrangements, attachments or identifications means
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- F17C2205/0123—Mounting arrangements characterised by number of vessels
- F17C2205/013—Two or more vessels
- F17C2205/0134—Two or more vessels characterised by the presence of fluid connection between vessels
- F17C2205/0142—Two or more vessels characterised by the presence of fluid connection between vessels bundled in parallel
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- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F17—STORING OR DISTRIBUTING GASES OR LIQUIDS
- F17C—VESSELS FOR CONTAINING OR STORING COMPRESSED, LIQUEFIED OR SOLIDIFIED GASES; FIXED-CAPACITY GAS-HOLDERS; FILLING VESSELS WITH, OR DISCHARGING FROM VESSELS, COMPRESSED, LIQUEFIED, OR SOLIDIFIED GASES
- F17C2205/00—Vessel construction, in particular mounting arrangements, attachments or identifications means
- F17C2205/03—Fluid connections, filters, valves, closure means or other attachments
- F17C2205/0302—Fittings, valves, filters, or components in connection with the gas storage device
- F17C2205/0311—Closure means
- F17C2205/032—Closure means pierceable
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- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F17—STORING OR DISTRIBUTING GASES OR LIQUIDS
- F17C—VESSELS FOR CONTAINING OR STORING COMPRESSED, LIQUEFIED OR SOLIDIFIED GASES; FIXED-CAPACITY GAS-HOLDERS; FILLING VESSELS WITH, OR DISCHARGING FROM VESSELS, COMPRESSED, LIQUEFIED, OR SOLIDIFIED GASES
- F17C2205/00—Vessel construction, in particular mounting arrangements, attachments or identifications means
- F17C2205/03—Fluid connections, filters, valves, closure means or other attachments
- F17C2205/0302—Fittings, valves, filters, or components in connection with the gas storage device
- F17C2205/0323—Valves
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- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F17—STORING OR DISTRIBUTING GASES OR LIQUIDS
- F17C—VESSELS FOR CONTAINING OR STORING COMPRESSED, LIQUEFIED OR SOLIDIFIED GASES; FIXED-CAPACITY GAS-HOLDERS; FILLING VESSELS WITH, OR DISCHARGING FROM VESSELS, COMPRESSED, LIQUEFIED, OR SOLIDIFIED GASES
- F17C2205/00—Vessel construction, in particular mounting arrangements, attachments or identifications means
- F17C2205/03—Fluid connections, filters, valves, closure means or other attachments
- F17C2205/0302—Fittings, valves, filters, or components in connection with the gas storage device
- F17C2205/037—Quick connecting means, e.g. couplings
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- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F17—STORING OR DISTRIBUTING GASES OR LIQUIDS
- F17C—VESSELS FOR CONTAINING OR STORING COMPRESSED, LIQUEFIED OR SOLIDIFIED GASES; FIXED-CAPACITY GAS-HOLDERS; FILLING VESSELS WITH, OR DISCHARGING FROM VESSELS, COMPRESSED, LIQUEFIED, OR SOLIDIFIED GASES
- F17C2205/00—Vessel construction, in particular mounting arrangements, attachments or identifications means
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- F17C2205/0388—Arrangement of valves, regulators, filters
- F17C2205/0394—Arrangement of valves, regulators, filters in direct contact with the pressure vessel
- F17C2205/0397—Arrangement of valves, regulators, filters in direct contact with the pressure vessel on both sides of the pressure vessel
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- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
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- F17C2205/00—Vessel construction, in particular mounting arrangements, attachments or identifications means
- F17C2205/05—Vessel or content identifications, e.g. labels
- F17C2205/052—Vessel or content identifications, e.g. labels by stickers
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- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F17—STORING OR DISTRIBUTING GASES OR LIQUIDS
- F17C—VESSELS FOR CONTAINING OR STORING COMPRESSED, LIQUEFIED OR SOLIDIFIED GASES; FIXED-CAPACITY GAS-HOLDERS; FILLING VESSELS WITH, OR DISCHARGING FROM VESSELS, COMPRESSED, LIQUEFIED, OR SOLIDIFIED GASES
- F17C2205/00—Vessel construction, in particular mounting arrangements, attachments or identifications means
- F17C2205/05—Vessel or content identifications, e.g. labels
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- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
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- F17C—VESSELS FOR CONTAINING OR STORING COMPRESSED, LIQUEFIED OR SOLIDIFIED GASES; FIXED-CAPACITY GAS-HOLDERS; FILLING VESSELS WITH, OR DISCHARGING FROM VESSELS, COMPRESSED, LIQUEFIED, OR SOLIDIFIED GASES
- F17C2209/00—Vessel construction, in particular methods of manufacturing
- F17C2209/23—Manufacturing of particular parts or at special locations
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- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
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- F17C2221/00—Handled fluid, in particular type of fluid
- F17C2221/01—Pure fluids
- F17C2221/014—Nitrogen
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- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F17—STORING OR DISTRIBUTING GASES OR LIQUIDS
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- F17C2221/00—Handled fluid, in particular type of fluid
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- F17C2221/016—Noble gases (Ar, Kr, Xe)
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- F17C2223/00—Handled fluid before transfer, i.e. state of fluid when stored in the vessel or before transfer from the vessel
- F17C2223/01—Handled fluid before transfer, i.e. state of fluid when stored in the vessel or before transfer from the vessel characterised by the phase
- F17C2223/0107—Single phase
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- F17C2223/00—Handled fluid before transfer, i.e. state of fluid when stored in the vessel or before transfer from the vessel
- F17C2223/03—Handled fluid before transfer, i.e. state of fluid when stored in the vessel or before transfer from the vessel characterised by the pressure level
- F17C2223/031—Not under pressure, i.e. containing liquids or solids only
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- F17C2227/00—Transfer of fluids, i.e. method or means for transferring the fluid; Heat exchange with the fluid
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- F17C2260/00—Purposes of gas storage and gas handling
- F17C2260/02—Improving properties related to fluid or fluid transfer
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- F17C2270/00—Applications
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Abstract
A container for a polarizable gas includes an elongate container sheet having a laminate of a sealing layer and a barrier layer, a sealed container cavity defined by the container sheet by perimetrically sealing the sealing layer upon itself so as to enclose the container cavity, and a quantity of a polarizable gas within the container cavity. A method of evacuating the polarzable gas from the container includes evacuating the passageway of a fitting attached to the container prior to puncturing the container and evacuating its contents through the fitting.
Description
- The present invention relates to the field of the storage containers. More specifically, the present invention is directed to a storage and delivery container for a polarizable gas.
- The use of hyperpolarized gases for ex-vivo and in-vivo imaging is well known. As models for the widespread distribution of hyperpolarized gas doses become better defined, it is clear that a system providing for point-of-use polarization of gases be developed. In order to decrease the risk of waste, it is desirable to provide a unit-dose container for a polarizable gas which may be delivered to an imaging center and used on a per-patient basis. Moreover, a method for dispensing the contents of the container must ensure the gas contents do not become contaminated with ambient air.
- The present invention addresses the need in the art for a unit-dose container for a hyperpolarizable gas which maintains the integrity of a dose through both storage and discharge.
- The present invention addresses the needs of the art by providing a container for a polarizable gas formed from an elongate container sheet having a laminate of a sealing layer and a barrier layer. A sealed container cavity is defined by the container sheet by perimetrically sealing the sealing layer upon itself so as to enclose the container cavity. A quantity of a polarizable gas is provided within the container cavity.
- The containers of the present invention are contemplated to provide a unit dose of a polarizable gas useful for hyperpolarized gas imaging and spectroscopic applications as is known with conventional magnetic resonance imaging (MRI) equipment. The containers desirably enclose approximately 0.5 liters of a gas at atmospheric pressure with sufficient capacity to accommodate thermal expansion of the gas without causing the container to rupture.
- The containers are formed from a multilaminate barrier sheet material for maximizing shelf-life. The barrier sheets desirably include a layer for providing scratch resistance to the container, a metallic layer for preventing permeation of the gas from the container, and a layer for allowing easy sealing of the container.
- The containers of the present invention may further include a connector fitting affixed to the barrier material for interfacing with a gas extraction device. The connector fitting defines an elongate fitting passageway through which the gas contents of the container may be evacuated. The connector fittings desirably do not penetrate the metallic layer of the multilaminate barrier sheet material so as not to degrade the blocking characteristics of the material. The connector is desirably bonded or heat-sealed to the outside of the container during manufacturing. Puncture of the container for extraction of the gas contents may be accomplished through the connector fitting.
- The containers of the present invention may be attached to an evacuation device which engages the connector fitting in a fluid-tight manner. The fitting passageway is first evacuated of any contaminating gases prior to puncturing the container and evacuating the gas contents through the fitting passageway. Desirably, the container is punctured through the fitting passageway.
- FIG. 1 depicts a first container of the present invention.
- FIGS. 2A and 2B depict alternate multilaminate barriers of the containers of the present invention.
- FIGS.3-4 depict another container of the present invention.
- FIG. 5 depicts yet another container of the present invention.
- FIG. 6 depicts still another container of the present invention.
- FIG. 7 depicts a gas loading system adapted for the container of FIG. 5.
- FIG. 8 depicts still yet another container of the present invention.
- FIG. 9 depicts a gas loading system adapted for the container of FIG. 7.
- As shown in FIG. 1, the present invention provides a
container 10 for storing and delivering a mixture having a polarizable gas such as 3He or 129Xe. The container is generally a bag or soft container and is desirably formed from any material suitable for the purpose of storing the gas prior to its polarization.Container 10 is scalable so as to hold any size of a pre-selected dose of the polarizable gas. Each dose of the polarizable gas is contemplated to include some amount of another gas, such as N2. For example, by way of illustration and not of limitation, each container of the present invention may hold a 0.5 liter gas mixture which comprises 99.25% 3He and 0.75% N2. -
Container 10 is desirably formed by a singleelongate sheet 12 of container material and, optionally, an attachedfitting 14.Container sheet 12 is folded about a transversely-extendingcrease area 16 so that the overlapping perimetrical edges ofsheet 12 may be welded together to form a partialperimetrical seam 18 extending between opposed ends 16 a and 16 b ofcrease area 16.Container sheet 12 thereby defines an enclosedcontainer cavity 20 for storing a dose of polarizable gas. The present invention contemplates that Fitting 14 may be adhered or bonded to anoutside surface 12 a ofcontainer 10 so as to provide an adaptor for establishing fluid communication betweencavity 20 and the polarization region of a polarizer device, not shown. The present invention further contemplates thatcontainer 10 may be formed from a fully perimetrical weld of a first andsecond container sheet 12 positioned in facing opposition so as to form enclosedcavity 20. - As shown in FIG. 2A,
sheet 12 is desirably formed from a multilayer laminate made from, as viewed fromcavity 20 tooutside surface 12 a, at least a sheet ofpolyethylene 13 and a sheet ofaluminum foil 15. The present invention further contemplates including layers of polyester and PET in constitutingsheet 12. A polyethylene is desirably provided to form the interior layer ofcontainer 10 so as to ensure sealing ofcavity 20 byperimetrical seam 18. The aluminum layer is contemplated to act as a barrier for the hyperpolarizable gas. It is further contemplated to metalize a polyethylene or polyester layer so as to provide for both heat sealing and gas barrier. With additional reference to FIG. 2B, anotherpolyester layer 19, such as polyvinylidene chloride, is further contemplated for providing improved tear or puncture resistance. APET layer 13 is contemplated to provide improved scratch or abrasion resistance. The present invention further contemplates alternate combinations of the order and location of the laminated layers may be provided to formsheet 12. - Fitting14 is desirably formed from a suitable plastic material and includes an elongate
cylindrical wall 22 defining anelongate passageway 24 extending betweenopposed wall ends annular flange 30 extending aboutsecond end 28 ofcylindrical wall 22 so as to provide a larger surface area for bonding tooutside surface 12 a ofcontainer sheet 12.Annular flange 30 may either define a centralopening exposing surface 12 a topassageway 24 or may be a solid member which further isolates passagway 24 fromsurface 12 a. The means for affixing fitting 14 tosheet 12 desirably does not penetrate thealuminum layer 15 so as to minimize permeation of the stored gas therepast. It is contemplated thatcylindrical wall 22 may be formed with luer-lock means extending either outwardly therefrom or inwardly intopassageway 24 for engaging a complimentary fitting on a polarizer. Outwardly-projectinglugs passageway 24 and then bothpuncture container 10 andevacuate cavity 20. In embodiments of the present invention lacking the attachedfitting 14, the present invention contemplates that the polarizer will incorporate the means for providing a fluid-tight and evacuated attachment to fitting 14 as well as the means to puncturecontainer sheet 12 and evacuatecavity 20. - Additional steps in the construction and filling of
container 10 will be apparent from the descriptions hereinbelow. - FIGS. 3 and 4 depict a
second container 110 of the present invention.Container 110 is desirably formed from a singleelongate container sheet 112 and, optionally, a fitting 114.Container sheet 112 and fitting 114 are similar tosheet 12 and fitting 14 as previously described whereby like numbering describes like features.Container sheet 112 is folded about acrease 116 and the overlying edges are welded together so as to form a partialperimetrical seam 118 bounded bycrease 116.Sheet 112 thereby provides acontainer cavity 120 for storing a dose of polarizable gas. - As shown in FIG. 4,
container sheet 112 andseam 118 form anopen inlet port 125 defining aninlet passagway 130 in fluid communication withcavity 120. The polarizable gas is introduced intocavity 120 throughpassageway 130. The present invention contemplates that a fluid-tight seal may be established between a filling device, not shown, andcontainer 110 atinlet port 125.Container 110 will undergo at least one cycle of receiving a purge gas, such as N2, throughpassageway 130 followed by a vacuum extraction of the contents ofcavity 120 throughpassageway 130. It is desirable to evacuate all of the oxygen and other gases which may be entrapped incavity 120 during the fabrication process. After undergoing the desired number of purge/vacuum cycles, the filling device will then deliver the polarizable gas throughpassageway 130 intocavity 120. While maintaining a fluid tight engagement aboutinlet port 125,seam 118 is completed acrosspassageway 130 so as to isolatecavity 120 from the outside environment. - FIG. 5 depicts yet another
container 210 of the present invention.Container 210 is formed from acontainer sheet 212 and, optionally, aclosed fitting 214.Container sheet 212 is similar tosheet 12 as previously described whereby like numbering describes like features.Container sheet 212 is folded about acrease 216 such that overlying edges thereof may be welded together to form a partialperimetrical seam 218 and thereby define an enclosed container cavity 220. Cavity 220 is sized to contain a dose of polarizable gas for use in an imaging or spectrographic procedure.Seam 218 may be formed having a large enough surface area to accommodate various markers or indicia such as lables or bar codes.Container 210 is desirably formed having aninlet port 225 defining apassageway 230 in fluid communication with container cavity 220. -
Container 210 is further shown incorporating sealed fitting 214 intoseam 218. Sealed fitting 214 defines an elongate cylindrical fitting passageway 224 exteding in fluid communication with open end 226 thereof. Passageway 224 is in obstructed fluid communication with cavity 220. The present invention further contemplates affixing an adaptor, such as fitting 14, to the outside surface 212 a ofcontainer 210. It is also contemplated that passageway 224 will be evacuated of any contaminating gases prior to puncturing the closed end of fitting 214. Sealed fitting 214 may be punctured so as to render the contents ofcavity 210 accessible for evacuation into a polarizer. - FIG. 6 depicts a dual-
dose container 310 of the present invention. A dual-dose container is intended to provide enough polarizable gas for performing a full imaging or spectrometry procedure for a patient.Container 310 is desirably formed by perimetrically and transversely welding a first andsecond container sheet Perimetrical seam 318 andtransverse seam 319 define first and secondenclosed cavities Cavities Container 310 is shown as providing first and secondopen inlet ports seam 318 so as to define first and second passageways in fluid communication with first andsecond cavities cavities ports seam 318 may be completed so as to isolateports cavities Seam 318 also incorporateselongate fittings - FIG. 8 shows a
gas loading system 500 for filling dual-dose container 310.Gas loading system 500 includes acannister supply 501 of N2 and a hyperpolarizable gas.Gas loading system 500 further includes first and second gas injector probes 502 and 504 receivable ininlet ports probes inlet ports cavities - FIG. 9 depicts a unit-
dose cylinder 610 of the present invention.Cylinder 610 provides a rigid container for transporting a hyperpolarizable gas. The contents ofcylinder 610 may be dispensed into a flexible gas container of the present invention.Cylinder 610 is desirably formed from aluminum or stainless steel.Cylinder 610 includes anouter container wall 612 having anopen end 614 covered by apuncturable cover 615.Container wall 612 defines andinterior cavity 616, in fluid communication withopen end 614.Open end 614 may further include therein a poppet-type or ball-type valve for controlling the introduction and evacuation of gases into and out fromcavity 616. It is further contemplated thatcontainer wall 612 is annularly scored or weakened aboutopen end 614 wherecylinder 610 may be opened. - FIG. 8 depicts a
gas loading system 700 adapted for filling a unit-dose container of the present invention.Gas loading system 700 includes arotary turntable 702 for accommodating a number of unit-dose cylinders 610 thereon.Turntable 702 positions eachend 614 ofcylinder 610 in underlying spaced registry below anextraction nozzle 704.Extraction nozzle 704 may be extended into sealed contact aboutend 614 of acylinder 610 and includes the means to purge the void extending between the openable end of the cylinder and a gas delivery valve withinfill nozzle 704. Fillnozzle 704 includes the means for purging oxygen from the void prior to communicating withcavity 616 and extracting the polarizable gas mixture therefrom. The polarizable gas mixture may include, for purposes of illustration and not of limitation, a polarizable gas and N2.Gas loading system 700 also includes means for filling a flexible container of the present invention as previously described. - While the particular embodiment of the present invention has been shown and described, it will be obvious to those skilled in the art that changes and modifications may be made without departing from the teachings of the invention. The matter set forth in the foregoing description and accompanying drawings is offered by way of illustration only and not as a limitation. The actual scope of the invention is intended to be defined in the following claims when viewed in their proper perspective based on the prior art.
Claims (13)
1. A container for a polarizable gas comprising:
an elongate container sheet comprising a laminate of a sealing layer and a barrier layer;
a sealed container cavity defined by said container sheet by perimetrically sealing said sealing layer upon itself so as to enclose said container cavity; and
a quantity of a polarizable gas within said container cavity.
2. The container of claim 1 , wherein said container sheet further comprises a laminate of a metalized polymeric layer for providing both a heat sealable layer and a gas barrier for said polarizable gas.
3. The container of claim 2 , wherein said container sheet further comprises a laminate including a PET layer for providing abrasion resistance to the container.
4. The container of claim 1 , wherein said container cavity is further defined between said perimetrical seam extending between a substantially linear crease folded into said container sheet.
5. The container of claim 1 , wherein said container cavity is further defined between said container sheet and a second container sheet perimetrically sealed together.
6. The container of claim 1 , further comprising a mixture of said hyperpolarizable gas with a non-hyperpolarizable gas.
7. The container of claim 6 , wherein said mixture comprises approximately 99.25% 3He and approximately 0.75% N2.
8. The container of claim 1 , further comprising a elongate fluid exchange fitting mounted upon an outside surface of said container sheet, said fitting being connectable to a gas withdrawal system for evacuating said mixture from said container cavity.
9. A method for preparing an expandable storage container for receiving a quantity of hyperpolarizable gas, comprising the steps of:
forming a container cavity with an elongate container sheet;
perimetrically sealing said container cavity by joining the overlying perimetrical edges together about a fill port;
providing a quantity of purge gas into the hyperpolarizable gas container through said fill port;
expanding the hyperpolarized gas container by directing a quantity of purge gas therein;
collapsing the hyperpolarized gas container by removing purge gas therefrom; filling said container cavity with a hyperpolarizable gas mixture; and
sealing said fill port so as to provide a sealed container cavity holding said hyperpolarizable gas mixture.
10. The method of claim 9 , wherein said forming step further comprises forming said container cavity between a first and second container sheet.
11. The method of claim 9 , further comprising the step of attaching an evacuation fitting to an outside surface of said container, said fitting being connectable to a gas withdrawal system for evacuating said mixture from said container cavity.
12. A method of withdrawing a polarizable gas mixture from a container holding the gas mixture, the container comprising an elongate container sheet comprising a laminate of a sealing layer and a barrier layer; a sealed container cavity defined by the container sheet by folding over the container sheet and perimetrically sealing the sealing layer upon itself so as to enclose the container cavity; and a quantity of a polarizable gas within the container cavity, the container further having a fitting affixed thereto, the fitting defining a passageway through which the gas mixture is to be evacuated, comprising the steps of:
engaging the fitting with a dispense mechanism so as to form a fluid-tight seal therebetween;
evacuating air from the fitting passageway;
puncturing the container so that the fitting passageway is in unobstructed fluid communication with the container cavity; and
evacuating the gas mixture from the container cavity through the fitting passageway.
13. The method of claim 12 , wherein said puncturing step further comprises the step of puncturing the container through the fitting passageway.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US10/279,042 US20030106902A1 (en) | 2001-10-23 | 2002-10-23 | Storage and delivery containers for imaging and spectroscopic agents |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
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US34831501P | 2001-10-23 | 2001-10-23 | |
US10/279,042 US20030106902A1 (en) | 2001-10-23 | 2002-10-23 | Storage and delivery containers for imaging and spectroscopic agents |
Publications (1)
Publication Number | Publication Date |
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US20030106902A1 true US20030106902A1 (en) | 2003-06-12 |
Family
ID=26959422
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
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US10/279,042 Abandoned US20030106902A1 (en) | 2001-10-23 | 2002-10-23 | Storage and delivery containers for imaging and spectroscopic agents |
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US (1) | US20030106902A1 (en) |
Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20040222233A1 (en) * | 2003-05-05 | 2004-11-11 | Cryovac, Inc. | System and pouch for dispensing syrups, toppings, and other products |
US20050236428A1 (en) * | 2004-04-26 | 2005-10-27 | Paige Poulos Communications | Portable beverage container |
US20070066955A1 (en) * | 2003-10-21 | 2007-03-22 | Novo Nordisk A/S | Reservoir device with integrated mounting means |
EP2246272A1 (en) * | 2008-02-08 | 2010-11-03 | Wallha Co., Ltd. | Squeezing device and packaging bag for viscous liquid |
US20130172831A1 (en) * | 2011-08-31 | 2013-07-04 | Leslie A. Voss | Liquid dispensing reservoir |
Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6120730A (en) * | 1998-06-26 | 2000-09-19 | Tetra Laval Holdings & Finance, Sa | Heat and hydrogen peroxide gas sterilization of container |
US6128918A (en) * | 1998-07-30 | 2000-10-10 | Medi-Physics, Inc. | Containers for hyperpolarized gases and associated methods |
US6179822B1 (en) * | 1998-01-20 | 2001-01-30 | Bracco Research Usa | Single use universal access device/medical container assembly |
US6287289B1 (en) * | 1998-01-20 | 2001-09-11 | Bracco Diagnostics Inc. | Multiple use universal connector |
US6423387B1 (en) * | 1998-06-17 | 2002-07-23 | Medi-Physics, Inc. | Resilient containers for hyperpolarized gases and associated methods |
-
2002
- 2002-10-23 US US10/279,042 patent/US20030106902A1/en not_active Abandoned
Patent Citations (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6179822B1 (en) * | 1998-01-20 | 2001-01-30 | Bracco Research Usa | Single use universal access device/medical container assembly |
US6287289B1 (en) * | 1998-01-20 | 2001-09-11 | Bracco Diagnostics Inc. | Multiple use universal connector |
US6423387B1 (en) * | 1998-06-17 | 2002-07-23 | Medi-Physics, Inc. | Resilient containers for hyperpolarized gases and associated methods |
US20030009126A1 (en) * | 1998-06-17 | 2003-01-09 | Zollinger David L. | Resilient containers for hyperpolarized gases and associated methods |
US6526778B2 (en) * | 1998-06-17 | 2003-03-04 | Medi-Physics, Inc. | Resilient containers for hyperpolarized gases and associated methods |
US6120730A (en) * | 1998-06-26 | 2000-09-19 | Tetra Laval Holdings & Finance, Sa | Heat and hydrogen peroxide gas sterilization of container |
US6128918A (en) * | 1998-07-30 | 2000-10-10 | Medi-Physics, Inc. | Containers for hyperpolarized gases and associated methods |
Cited By (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20040222233A1 (en) * | 2003-05-05 | 2004-11-11 | Cryovac, Inc. | System and pouch for dispensing syrups, toppings, and other products |
US6860407B2 (en) * | 2003-05-05 | 2005-03-01 | Cryovac, Inc. | System and pouch for dispensing syrups, toppings, and other products |
US20070066955A1 (en) * | 2003-10-21 | 2007-03-22 | Novo Nordisk A/S | Reservoir device with integrated mounting means |
US8821472B2 (en) * | 2003-10-21 | 2014-09-02 | Novo Nordisk A/S | Reservoir device with integrated mounting means |
US20050236428A1 (en) * | 2004-04-26 | 2005-10-27 | Paige Poulos Communications | Portable beverage container |
EP2246272A1 (en) * | 2008-02-08 | 2010-11-03 | Wallha Co., Ltd. | Squeezing device and packaging bag for viscous liquid |
US20110089193A1 (en) * | 2008-02-08 | 2011-04-21 | Wallha Co., Ltd. | Squeezing device and packaging bag for viscous liquid |
EP2246272A4 (en) * | 2008-02-08 | 2013-07-03 | Wallha Co Ltd | Squeezing device and packaging bag for viscous liquid |
US8684241B2 (en) * | 2008-02-08 | 2014-04-01 | Wallha Co., Ltd. | Squeezing device and packaging bag for viscous liquid |
US20130172831A1 (en) * | 2011-08-31 | 2013-07-04 | Leslie A. Voss | Liquid dispensing reservoir |
US9801757B2 (en) * | 2011-08-31 | 2017-10-31 | Johnson & Johnson Vision Care, Inc. | Liquid dispensing reservoir |
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Owner name: MEDI-PHYSICS, INC., NEW JERSEY Free format text: ASSIGNMENT OF ASSIGNORS INTEREST;ASSIGNOR:BOLAM, KENNETH;REEL/FRAME:013524/0889 Effective date: 20021120 |
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Owner name: POLAREAN INC., NORTH CAROLINA Free format text: ASSIGNMENT OF ASSIGNORS INTEREST;ASSIGNOR:MEDI-PHYSICS INC.;REEL/FRAME:028509/0240 Effective date: 20111219 |
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