US20020019649A1 - Closure device and method for tissue repair - Google Patents
Closure device and method for tissue repair Download PDFInfo
- Publication number
- US20020019649A1 US20020019649A1 US09/886,367 US88636701A US2002019649A1 US 20020019649 A1 US20020019649 A1 US 20020019649A1 US 88636701 A US88636701 A US 88636701A US 2002019649 A1 US2002019649 A1 US 2002019649A1
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- flexible member
- anchor
- suture
- tissue
- fixation
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- JMDVAYXLFHPGMJ-UHFFFAOYSA-N CCCC(CF)[IH]#[O] Chemical compound CCCC(CF)[IH]#[O] JMDVAYXLFHPGMJ-UHFFFAOYSA-N 0.000 description 1
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/04—Surgical instruments, devices or methods, e.g. tourniquets for suturing wounds; Holders or packages for needles or suture materials
- A61B17/0401—Suture anchors, buttons or pledgets, i.e. means for attaching sutures to bone, cartilage or soft tissue; Instruments for applying or removing suture anchors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/04—Surgical instruments, devices or methods, e.g. tourniquets for suturing wounds; Holders or packages for needles or suture materials
- A61B17/0469—Suturing instruments for use in minimally invasive surgery, e.g. endoscopic surgery
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/04—Surgical instruments, devices or methods, e.g. tourniquets for suturing wounds; Holders or packages for needles or suture materials
- A61B17/06—Needles ; Sutures; Needle-suture combinations; Holders or packages for needles or suture materials
- A61B17/06166—Sutures
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/04—Surgical instruments, devices or methods, e.g. tourniquets for suturing wounds; Holders or packages for needles or suture materials
- A61B17/0401—Suture anchors, buttons or pledgets, i.e. means for attaching sutures to bone, cartilage or soft tissue; Instruments for applying or removing suture anchors
- A61B2017/0409—Instruments for applying suture anchors
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/04—Surgical instruments, devices or methods, e.g. tourniquets for suturing wounds; Holders or packages for needles or suture materials
- A61B17/0401—Suture anchors, buttons or pledgets, i.e. means for attaching sutures to bone, cartilage or soft tissue; Instruments for applying or removing suture anchors
- A61B2017/0414—Suture anchors, buttons or pledgets, i.e. means for attaching sutures to bone, cartilage or soft tissue; Instruments for applying or removing suture anchors having a suture-receiving opening, e.g. lateral opening
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/04—Surgical instruments, devices or methods, e.g. tourniquets for suturing wounds; Holders or packages for needles or suture materials
- A61B17/0401—Suture anchors, buttons or pledgets, i.e. means for attaching sutures to bone, cartilage or soft tissue; Instruments for applying or removing suture anchors
- A61B2017/0417—T-fasteners
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/04—Surgical instruments, devices or methods, e.g. tourniquets for suturing wounds; Holders or packages for needles or suture materials
- A61B17/0401—Suture anchors, buttons or pledgets, i.e. means for attaching sutures to bone, cartilage or soft tissue; Instruments for applying or removing suture anchors
- A61B2017/0446—Means for attaching and blocking the suture in the suture anchor
- A61B2017/0459—Multiple holes in the anchor through which the suture extends and locking the suture when tension is applied
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/04—Surgical instruments, devices or methods, e.g. tourniquets for suturing wounds; Holders or packages for needles or suture materials
- A61B17/0401—Suture anchors, buttons or pledgets, i.e. means for attaching sutures to bone, cartilage or soft tissue; Instruments for applying or removing suture anchors
- A61B2017/0464—Suture anchors, buttons or pledgets, i.e. means for attaching sutures to bone, cartilage or soft tissue; Instruments for applying or removing suture anchors for soft tissue
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- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/04—Surgical instruments, devices or methods, e.g. tourniquets for suturing wounds; Holders or packages for needles or suture materials
- A61B17/0469—Suturing instruments for use in minimally invasive surgery, e.g. endoscopic surgery
- A61B2017/0475—Suturing instruments for use in minimally invasive surgery, e.g. endoscopic surgery using sutures having a slip knot
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- A—HUMAN NECESSITIES
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- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/04—Surgical instruments, devices or methods, e.g. tourniquets for suturing wounds; Holders or packages for needles or suture materials
- A61B17/0469—Suturing instruments for use in minimally invasive surgery, e.g. endoscopic surgery
- A61B2017/0477—Suturing instruments for use in minimally invasive surgery, e.g. endoscopic surgery with pre-tied sutures
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/04—Surgical instruments, devices or methods, e.g. tourniquets for suturing wounds; Holders or packages for needles or suture materials
- A61B2017/0496—Surgical instruments, devices or methods, e.g. tourniquets for suturing wounds; Holders or packages for needles or suture materials for tensioning sutures
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/08—Muscles; Tendons; Ligaments
- A61F2/0811—Fixation devices for tendons or ligaments
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T24/00—Buckles, buttons, clasps, etc.
- Y10T24/39—Cord and rope holders
- Y10T24/3916—One-piece
Definitions
- the invention relates to a closure device and method for tissue repair.
- Fibrous tissue wounds such as muscle, ligament, and cartilage tears
- sutures can be repaired arthroscopically using sutures.
- a surgeon would insert two suture needles into the tissue with sutures attached, thread the sutures across the wound, and then tie knots to fix the free ends of the sutures within the tissue.
- FIG. 1 A perspective view of a suture anchor
- FIG. 1 A perspective view of a suture anchor
- FIG. 1 A perspective view of a suture anchor
- FIG. 1 A perspective view of a suture anchor
- FIG. 1 A perspective view of a suture anchor
- FIG. 1 A perspective view of a suture anchor
- FIG. 1 A perspective view of a suture anchor
- FIG. 1 A perspective view of a suture anchor
- FIG. 1 A perspective view of a suture anchor
- FIG. 1 A perspective view of a suture anchor
- FIG. 1 A perspective view of a suture anchor
- FIG. 1 A perspective view of a suture anchor
- FIG. 1 A perspective view of a suture anchor
- FIG. 1 A perspective view of a suture anchor
- FIG. 1 A perspective view of a suture anchor
- FIG. 1 A perspective view of a suture anchor
- FIG. 1 A perspective view of a suture anchor
- FIG. 1 A perspective view of a suture anchor
- the invention features a wound closure device that includes a first anchor, a second anchor, and a flexible member that connects the first anchor to the second anchor.
- the flexible member is movably attached to the second anchor, such that pulling on a free end of the flexible member shortens a length of the flexible member between the first and second anchors.
- Embodiments of this aspect of the invention may include one or more of the following features.
- the movable attachment of the flexible member to the second anchor allows the length of the flexible member between the first and second anchors to be shortened, but not lengthened.
- the movable attachment can be a knot formed in the flexible member at the second anchor.
- the knot includes, e.g., a first portion of the flexible member that forms a loop, and a second portion (which might include the free end) that passes over a surface of the second anchor and through the loop.
- the surface can be, e.g., an exterior surface of the second anchor.
- the second anchor can include a first section that defines a plurality of holes through which the first portion of the flexible member passes to form the loop.
- a second section of the second anchor defines a passage that connects to the partially enclosed region, and the free end of the suture passes through this passage.
- the second anchor can include a rounded body and an appendage attached to the rounded body, where the rounded body and the appendage define a partially enclosed region therebetween. At least a portion of the flexible member passes through the partially enclosed region. In addition, the flexible member might wrap around the rounded body.
- the rounded body can have a generally cylindrical shape, sized to fit within the bore of a hollow needle, and an axial groove.
- the groove extends across an axial length of the rounded body.
- the cross-sectional shape of the rounded body can be, e.g., a rectangle, an L, or a D.
- the second anchor can also have a generally hemispherical shape, a generally crescent shape, or a T-shape.
- the crescent-shaped anchor can have sharp tip configured to penetrate tissue.
- the second anchor defines a through-hole through which the flexible member passes.
- the device can also include a second flexible member that passes through the through-hole, where the second flexible member has a thickened portion that has a width greater than a width of the through-hole, such that the thickened portion cannot pass through the through-hole.
- the first anchor includes, e.g., a generally cylindrical body sized and shaped to fit within the bore of a hollow needle, and a projection, such as a longitudinal fin, extending from the cylindrical body.
- the first anchor can have a button shape.
- the first anchor can define a hole for passage of the flexible member therethrough, and the flexible member can be fixed to the first anchor.
- the flexible member can be a suture.
- the wound closure device further includes a retaining element coupled to the flexible member.
- the retaining element is slidably received by the flexible member and acts to limit loosening of the flexible member relative to the second fixation member.
- the retaining element is movable relative to the second fixation member and acts to limit loosening of the flexible member relative to the second fixation member.
- the invention features a wound closure kit that includes an open-tipped needle and first and second anchors connected by a flexible member disposed within a bore of the needle.
- Embodiments of this aspect of the invention may include one or more of the following features.
- the needle can define a longitudinal slit, and the first anchor can include a projection that protrudes through the slit.
- the second anchor can also include an appendage that protrudes through the slit, and the flexible member can be attached to the appendage.
- the flexible member can be fixed to the first anchor, but movably attached to the second anchor.
- the invention features a method of closing a tissue wound.
- the method includes: (a) providing a wound closure device that has a first anchor, a second anchor, and a flexible member movably attached to the second anchor; (b) positioning the first anchor against tissue; (c) passing the flexible member across the wound; (d) positioning the second anchor against tissue; and (e) pulling on a free end of the flexible member to shorten a length of the flexible member between the first and second anchors, thereby closing the wound.
- This aspect of the invention may include one or more of the following features.
- the flexible member can be slidably attached to the second anchor by a one-way knot, such that after completion of the pulling step, the length of the flexible member between the first and second anchors remains shortened.
- Part of the one-way knot can be disposed within a partially enclosed region of the second anchor.
- the partially enclosed region can be located such that during the pulling step, the portion of the one-way knot disposed within the partially enclosed region avoids contact with tissue.
- the first positioning step can include positioning the first anchor on a first side of the wound.
- the passing step can include passing the flexible member from the first side to a second side of the wound, engaging tissue on the second side, and returning the flexible member to the first side.
- the second positioning step can include positioning the second anchor on the first side of the wound.
- the first and second anchors can initially be disposed, at least partially, within the bore of a hollow, open-tipped needle.
- the first anchor can include a section that protrudes through a slit in the needle, and the first positioning step can include engaging the projection with tissue to remove the first anchor from the bore.
- the providing step can include providing a device in which the flexible member passes through a through-hole in the second anchor, and the device further includes a second flexible member that also passes through the through-hole.
- the second flexible member has a thickened portion that is wider than the through hole.
- the method further includes pulling the second flexible member until the thickened portion wedges into the through hole.
- the invention features a method of repairing a tear in a meniscus.
- the method includes: (a) providing a tear closing device having a first anchor, a second anchor, and a flexible member movably attached to the second anchor; (b) positioning the first anchor against the meniscus; (c) passing the flexible member across the tear; (d) positioning the second anchor against the meniscus; and (e) pulling on a free end of the flexible member to shorten a length of the flexible member between the first and second anchors, thereby closing the tear.
- Embodiments of this aspect of the invention can include one or more of the following features.
- the first positioning step can include positioning the first anchor against an external surface of the meniscus, on a first side of the tear
- the passing step can include passing the flexible member from the first side to a second side of the tear, engaging tissue on the second side, and returning the flexible member to the first side
- the second positioning step can include positioning the second anchor against the external surface.
- the first and second anchors can be positioned against external surfaces of the meniscus on opposite sides of the tear.
- a surgical method includes positioning a fixation member relative to tissue, moving a flexible member coupled to the fixation member relative to the fixation member to bring two tissue surfaces together, and moving a retaining element coupled to the flexible member relative to the fixation member.
- the retaining element acts to limit loosening of the flexible member relative to the fixation member.
- Embodiments of this aspect of the invention may include one or more of the following features.
- the step of moving the flexible member comprises pulling the flexible member.
- the step of moving the flexible member also accomplishes the step of moving the retaining element, which is, for example, a slip knot.
- the step of moving the retaining element includes moving the retaining element relative to the flexible element.
- the retaining element is, for example, a friction element which permits sliding of the retaining element relative to the flexible element in only one direction.
- the retaining element is in the form of an overhand knot, and the method includes advancing the overhand knot along the flexible element.
- the retaining element is in the form of a Chinese trap.
- the step of moving the flexible member includes pulling on only one end of the flexible member.
- the method includes positioning a second fixation member relative to the tissue.
- the second fixation member is coupled to the flexible member, either movably or fixedly.
- the step of moving the flexible member includes, for example, pulling on two ends of the flexible member or pulling on only one end of the flexible member.
- the step of positioning the fixation member includes positioning the fixation member on an outer surface of the tissue, and the two tissue surfaces brought together are both soft tissue.
- the fixation member is positioned in a bone hole, and one of the two tissue surfaces brought together is bone and the other soft tissue.
- the step of positioning the fixation member includes passing the fixation member through a loop of the flexible member.
- the loop is positioned within a tear in soft tissue.
- a method for repairing a tear in soft tissue includes advancing a fixation member coupled to a flexible member through tissue on either side of the tear and through a loop of the flexible member, and tensioning the flexible member to bring two tissue surfaces on either side of the tear together.
- Embodiments of this aspect of the invention may include one or more of the following features.
- the loop is positioned within the tear.
- the method includes pulling an end of the flexible member to bring the two tissue surfaces together.
- the fixation member is in the form of a barbed member.
- an apparatus for repairing a tear in soft tissue includes at least two fixation members, a flexible member substantially immovably secured to the first fixation member and movably coupled to the second fixation member, and a retaining element coupled to the flexible member.
- the retaining element is movable relative to the second fixation member and acts to limit loosening of the flexible member relative to the fixation member.
- an apparatus for repairing a tear in soft tissue includes at least two fixation members, a flexible member substantially immovably secured to the first fixation member and movably coupled to the second fixation member, and a retaining element coupled to the flexible member.
- the retaining element is slidably received by the flexible member and acts to limit loosening of the flexible member relative to the fixation member.
- an apparatus for repairing a tear in soft tissue includes a fixation member, and a flexible member movably coupled to the fixation member. A first end of the flexible member is looped back and secured to the flexible member to form a loop. The loop is remote from the fixation member.
- a flexible member holder includes a shaft, a first tine at an end region of the shaft defining a first region for receiving a first portion of a loop of a flexible member, and a second tine at the end region of the shaft defining a second region for receiving a second portion of the loop of the flexible member.
- Embodiments of this aspect of the invention may include one or more of the following features.
- the shaft is a tube.
- the first and second regions are grooves.
- a device for repairing a tear in a tissue includes a needle having a distal region defined between two holding elements, and a proximal region.
- a first fixation member is positioned within the distal region and a second fixation member is positioned within the proximal region.
- a flexible member is coupled to the first and second fixation members.
- Embodiments of this aspect of the invention may include one or more of the following features.
- a first of the holding elements is a crimp in the needle in the distal region, and the second holding element is a dimple or ramp extending into a lumen of the needle.
- the needle wall has a slot and the fixation members extend through the slot.
- the needle is sized to fit into an end of a protector tube.
- a push pin is sized to fit inside the needle.
- Embodiments of the invention may include one or more of the following advantages.
- the first and second anchors can be deployed using a single hollow needle, rather than two separate needles. After deploying a fixation member or anchor, the surgeon need not tie an additional knot.
- the length of a flexible member coupled to the fixation member can be adjusted after deploying the fixation member, allowing a surgeon to set the tension in the flexible member to a desired level.
- the length of a flexible member spanning across a tear in tissue can be shortened to close the tear by tensioning the flexible member with no additional manipulation being required to limit loosening of the flexible member.
- the device uses a flexible member, such as a suture, to close the tissue wound, rather than inflexible staples or tacks, the tissue is not significantly damaged when it expands and contracts.
- a flexible member such as a suture
- the fixation members do not damage the meniscal tissue when the knee moves.
- FIG. 1 is an illustration of a closure device according to the invention, shown mending a tear in soft tissue
- FIGS. 2 A- 2 I show a method of tying a slip knot in suture of the closure device of FIG. 1;
- FIG. 3 is a perspective view of a delivery device for inserting the closure device of FIG. 1 into soft tissue
- FIG. 4 is a perspective view of the delivery device of FIG. 3 shown with an outer sheath removed;
- FIG. 4A is a perspective view of a fixation member of the closure device of FIG. 1;
- FIG. 4B is a cross-sectional end view of the delivery device of FIG. 4, taken along lines 19 B- 19 B;
- FIG. 4C is a cross-sectional side view of an alternative embodiment of a needle of the delivery device of FIG. 3;
- FIG. 5 is side view of the delivery device of FIG. 3;
- FIG. 5A is a side view of a variable length depth stop for use with the delivery device of FIG. 3;
- FIG. 5B is a perspective view of a cannula for use with the delivery device of FIG. 3;
- FIGS. 6 - 11 show the delivery device in use inserting the closure device of FIG. 1 in soft tissue, with FIG. 7 being an exploded view of region 7 of FIG. 6;
- FIG. 12 is an illustration of the closure device of FIG. 1 with an alternative embodiment of a retaining element, shown mending a tear in soft tissue;
- FIGS. 12A and 12B show alternative embodiments of the retaining element of FIG. 11;
- FIG. 12C shows the retaining element of FIG. 12 in an alternative position
- FIG. 13 shows an additional alternative embodiment of a retaining element in the form of an overhand knot
- FIGS. 13A and 13B show an overhand knot and a knot pusher for advancing the overhand knot of FIG. 13;
- FIG. 14 is an illustration of an alternative embodiment of a closure device
- FIG. 14A shows an alternative arrangement of the closure device and delivery device of FIG. 14;
- FIG. 14B is an illustration of an alternative embodiment of a closure device
- FIG. 15 is an illustration of an alternative embodiment of a closure device for use in attaching soft tissue to bone
- FIG. 16A is a perspective view of a wound closure device
- FIG. 16B is a side view of a first suture anchor of the wound closure device of FIG. 16A;
- FIG. 16C is a side view of a second suture anchor of the device of FIG. 16A;
- FIG. 16D is an enlarged view of a braided suture
- FIG. 17 is a perspective, cut-away view of the wound closure device of FIG. 17A implanted within a meniscus;
- FIGS. 18A and 18B are sectional views of the second suture anchor and one-way knot of the wound closure device of FIG. 16A;
- FIG. 19 is a perspective view of a hollow needle, with the wound closure device of FIG. 16A disposed within a bore of the needle;
- FIGS. 20 A- 20 D are schematics illustrating deployment of the wound closure device of FIG. 16A into a meniscus using a plunger
- FIGS. 21 A- 21 D are schematics illustrating deployment of the wound closure device of FIG. 16A into a meniscus using a plunger and a spacer;
- FIG. 22A is a perspective view of an alternative first anchor design for a wound closure device, used in reverse deployment of the device;
- FIGS. 22 B- 22 E are schematics illustrating reverse deployment of a wound closure device
- FIGS. 23A and 23B are perspective views of the second suture anchor of FIGS. 16A and 16C, showing an alternative one-way knot configuration for the anchor;
- FIGS. 24 - 27 are sectional views of alternative configurations of the suture anchor and one-way knot of FIGS. 18A and 18B;
- FIG. 28A is a top view of a T-shaped second suture anchor
- FIG. 28B is a side view of the T-shaped suture anchor of FIG. 28A;
- FIG. 28C is a front view of a crescent-shaped second suture anchor
- FIG. 28D is a side view of the crescent-shaped suture anchor of FIG. 13C;
- FIGS. 29 - 31 are sectional views showing deployment of wound closure devices that include the crescent-shaped suture anchor of FIG. 28C;
- FIG. 32 is a perspective, partially schematic view of an alternative wound closure device implanted within a meniscus
- FIG. 33A is a perspective view of an alternative first suture anchor design for a wound closure device
- FIG. 33B is a perspective, cut-away view of the wound closure device of FIG. 33A implanted within a meniscus;
- FIG. 34 is a cross-sectional side view of an alternative embodiment of a closure device, shown mending a tear in soft tissue;
- FIG. 35 shows the closure device of FIG. 34 in use prior to securing the closure device in place
- FIG. 36 is a top view of the closure device of FIG. 34, shown after securing the closure device in place;
- FIG. 37 is a side view of a delivery device for inserting the closure device of FIG. 34 in soft tissue
- FIG. 37A is a perspective view of a distal section of the delivery device of FIG. 37 shown with a fixation member of the closure device of FIG. 34;
- FIG. 37B is a perspective view similar to that of FIG. 37A shown with the closure device of FIG. 34;
- FIG. 37C is an illustration of the closure device of FIG. 34;
- FIGS. 38 - 40 show the delivery device of FIG. 37 in use inserting the closure device of FIG. 34 in soft tissue;
- FIG. 41 is a cross-sectional side view of the closure device of FIG. 34 with an alternative embodiment of a retaining element, shown mending a tear in soft tissue;
- FIG. 42 is a cross-sectional side view of an alternative embodiment of a closure device, similar in use to the closure device of FIG. 34;
- FIGS. 43 and 44 are alternative embodiments of a fixation member of the closure device of FIG. 34.
- a closure device 8 for mending a tear 12 in soft tissue 14 e.g., meniscus of the knee joint, includes a flexible member, e.g., suture 10 , coupled to a first fixation member 16 and a second fixation member 18 .
- Suture 10 is fastened to fixation member 16 to limit movement of suture 10 relative to fixation member 16 , while suture 10 is movable relative to fixation member 18 .
- fixation members 16 and 18 lie on a surface 20 of tissue 14 , for example, the outer surface of the meniscus.
- Suture 10 has a first suture length 10 a extending from first fixation member 16 through tissue 14 , traversing tear 12 , and emerging at a surface 26 of tissue 14 ; a second suture length 10 b extending across surface 26 ; a third suture length 10 c extending back through tissue 14 , traversing tear 12 at a location spaced from first length 10 a, and emerging at tissue surface 20 where suture 10 loops through second fixation member 18 ; and a fourth suture length 10 d extending from second fixation member 18 through tissue 14 , traversing tear 12 , and emerging at surface 26 .
- Suture 10 has a free end 30 which the surgeon pulls, in the direction of arrow 32 , to bring sides 22 , 24 of tear 12 together into juxtaposition (as shown in FIG. 10).
- suture portion 10 c and suture portion 10 d are tied together prior to implantation of device 8 to form a retaining element in the form of a slip knot 28 that allows suture 10 to be pulled in the direction of arrow 32 , but does not allow tension on suture 10 to pull suture 10 in the opposite direction, which would allow tear 12 to re-open.
- fixation member 16 defines holes 16 a , 16 b for receiving suture 10
- fixation member 18 defines holes 18 a, 18 b for receiving suture 10
- suture 10 is attached to fixation member 16 by threading suture 10 through a needle 50 , and passing needle 50 and suture 10 through holes 16 a, 16 b in fixation member 16 (FIG. 2A).
- Suture 10 now defines a long suture section 52 and a short suture section 54 .
- Long suture section 52 is then attached to short suture section 54 by passing needle 50 and long suture section 52 through short suture section 54 at a region 56 (FIG. 2B). Pulling long suture section 52 away from fixation member 16 (FIG. 2C) then draws region 56 toward fixation member 16 forming a knot 60 (FIG. 2D). Suture 10 is now secured to fixation member 16 .
- suture 10 is now attached to fixation member 18 by passing long suture section 52 through holes 18 a, 18 b in second fixation member 18 (FIG. 2E).
- Long suture section 52 now defines a first suture length 62 and second suture length 64 .
- Slip knot 28 is formed by passing fixation member 16 under suture length 64 , over suture length 64 , and under suture length 62 , forming a loop 66 (FIG. 2F); then passing fixation member 16 over suture lengths 62 and 64 , forming a loop 68 (FIG. 2G); and then passing fixation member 16 under suture lengths 64 and 62 (FIG. 2G), and finally through loop 68 (FIG.
- a delivery device 99 for implanting device 8 in tissue 14 includes a sheath 200 and a needle 100 .
- Sheath 200 is preferably formed from plastic, and needle 100 is preferably metal.
- Needle 100 has an open distal end 111 with a pointed, tissue piercing tip 108 .
- Needle 100 has an inner surface 102 defining a lumen 104 and a slot 110 both extending to open distal end 111 .
- Slot 110 extends from an outer surface 106 of needle 100 to lumen 102 .
- needle 100 receives fixation member 16 and 18 within lumen 104 and slot 110 with suture 10 tied to fixation members 16 , 18 as illustrated in FIGS. 2 A- 2 I.
- Sheath 200 defines a lumen 202 which receives needle 100 and device 8 with suture 10 positioned between needle 100 and sheath 200 and extending through a hole 201 defined at a proximal end 203 of sheath 200 .
- Sheath 200 has a distal end 202 from which needle 100 extends.
- slot 110 has a proximal, closed end 120 and a distal open end 140 .
- Fixation members 16 and 18 (which are generally described in U.S. Ser. No. 09/453,120, supra) have the same shape with each fixation member including a cylindrical region 151 received within lumen 104 of needle 100 , and a fin 152 extending through slot 110 with a portion 154 of fin 152 extending beyond outer surface 106 of needle 100 .
- Fixation member 16 is located at a distal region 112 of slot 110
- fixation member 18 is located at a proximal region 114 of slot 110 .
- Distal end 111 of needle 100 is indented, for example, crimped at 150 , and inner surface 102 of needle 100 has a protrusion extending into lumen 104 , for example, a dimple 130 , near distal end 140 .
- Dimple 130 and crimp 150 are sized to resist unintentional passage of the fixation members either over dimple 130 or through open distal end 111 , though only a small force on the fixation members is needed to overcome the resisting load applied to the fixation members by crimp 150 and dimple 130 .
- Fixation members 16 , 18 have sloped surfaces 152 a which aid in passage through tissue, and a flat surface 154 a which aid in retention of the fixation member at their deployment sites.
- fixation member 18 is loaded in needle 100 by passing fixation member 18 through distal end 111 and sliding fixation member 18 along lumen 104 and slot 110 to proximal end 120 of slot 110 .
- Fixation member 16 is then loaded in needle 100 by passing fixation member 16 through distal end 111 and positioning fixation member 16 in region 112 .
- Dimple 130 and crimp 150 are then formed.
- Fixation member 16 is now restrained from unintentional movement in the proximal direction by dimple 130 and in the distal direction by crimp 150 .
- a needle 100 a includes a ramp 130 a formed by making three slits in a wall 101 of needle 100 a and bending a section of the wall toward the inside of the needle.
- needle 100 has a proximal end 160 mounted to a handle 180 .
- a push rod 170 (FIG. 4) used to advance fixation member 18 , as described below.
- Handle 180 includes an actuating slider 190 attached to push rod 170 for advancing push rod 170 .
- an outer protective tube 200 a can be placed over sheath 200 .
- Tube 200 a protects the needle tip during shipping. If it is desired to supply the surgeon with a variable length depth stop, tube 200 a can be provided with gradations 201 . The surgeon scores tube 200 a to provide the tube with the desired length for the surgical procedure.
- Tube 200 a is coupled to handle 190 by a loose interference fit to allow the surgeon to remove tube 200 a if tube 200 a is not being used during surgery.
- a removable cannula 202 a formed, for example, of a plastic material, can be placed over sheath 200 .
- Cannula 202 a has a distal, tissue penetrating tip 203 a and a slot 204 a extending from a proximal end 205 a of cannula 202 a to within about 0.02 inches of distal tip 203 a to define a distal region 206 a.
- Slot 204 a permits the removal of cannula 202 a from delivery device 99 after placement of the delivery device in the joint.
- cannula 202 a To remove cannula 202 a , the surgeon grasps the cannula and moves it laterally relative to sheath 200 , until sheath 200 slides through slot 204 a . The surgeon then pulls cannula 202 a proximally, which breaks cannula region 206 a, permitting complete removal of cannula 202 a.
- the user inserts delivery device 99 into, for example, the knee joint, and passes needle 100 through soft tissue 14 and across tear 12 , until needle tip 108 and fixation member 16 extend through tissue surface 20 .
- Dimple 130 prevents fixation member 16 from sliding proximally in response to forces acting on fixation member 16 during insertion through tissue 14 .
- Fixation member 16 is now positioned with flat, tissue facing surface 154 a of portion 154 of fin 152 extending beyond needle surface 106 engaging tissue surface 20 (FIG. 7). The user then pulls delivery device 99 proximally removing needle 100 from tissue 14 (FIG. 8).
- fixation member 16 slides distally out of open end 111 of needle 100 and remains at surface 20 .
- suture 110 with knot 28 is played out of delivery device 99 , with suture 10 extending through soft tissue 14 across tear 12 .
- fixation member 18 slides distally out of open end 111 of needle 100 and remains at surface 20 , as described above with reference to fixation member 16 .
- Free end 30 of suture 10 extends from sheath 200 , as shown in FIG. 11.
- the user grasps free end 30 of suture 10 with forceps or by hand and pulls on free end 30 of suture 10 .
- slip knot 28 moves closer to fixation member 18 .
- slip knot 28 will either be on tissue surface 26 or move within tissue 14 .
- Slip knot 28 allows suture 10 to slide in the direction of arrow 32 , but does not allow suture 10 to slide in the opposite direction.
- the tension placed on suture 10 by pulling on the suture relative to fixation members 16 , 18 acts to turn the fixation members such that their long sides 255 are in contact with tissue surface 20 . Excess suture 10 can then be cut off. Further manipulation of suture 10 is not needed to secure fixation members 16 , 18 , although the surgeon may wish to provide additional fastening as a back-up securement measure.
- a separate retaining element 210 is positioned on free end 30 of suture 10 . While pulling on free end 30 , the surgeon advances retaining element 210 through tissue 14 , in the direction of arrow 212 , until retaining element 210 is positioned against fixation member 18 , as shown in dashed line. This action acts to close tear 12 and secure device 8 in place.
- Retaining element 210 defines a through bore 216 for receiving suture 10 .
- the material of retaining element 210 e.g., acetal, is selected, and the diameter of through bore 216 is sized relative to suture 10 to provide the desired amount of friction between suture 10 and retaining element 210 for adequate securement.
- the user can slide suture 10 in the direction of arrow 212 , but adequate friction is provided between suture 10 and retaining element 210 to limit sliding of retaining element 210 in the opposite direction under normal loads in the knee joint.
- a retaining element 210 a defines two angled channels 218 , 220 for receiving free end 30 of suture 10 .
- Retaining element 210 a has a generally cylindrical surface 221 and ends 222 , 223 .
- Channel 218 has a first opening 224 at end 222 and second opening 225 on surface 221 .
- Channel 220 has a first opening 226 at end 223 and a second opening 227 on the same side of surface 221 as channel 218 .
- Suture 10 follows a tortuous path through channel 218 , over surface 221 between openings 225 and 227 , and then through channel 220 with free end 30 extending from opening 226 . The tortuous path aids in securement of device 8 .
- a retaining element 210 b defines two angled channels 218 a, 220 a each having a channel end 225 a , 227 a, respectively, on opposite sides of surface 221 .
- Suture 10 thus wraps part way around element 210 b to aid in securement of device 8 .
- retaining element 210 , 210 a , or 210 b is positioned along suture 10 between the portions of suture 10 passing through fixation member 18 .
- Retaining elements 210 , 210 a, 210 b are slidably received on suture 10 .
- the retaining element slides over suture 10 , changing position relative to fixation member 18
- suture 10 slides within the retaining element with the position of the retaining element being relatively unchanged relative to fixation member 18 .
- device 8 can be secured to tissue 14 using a simple overhand knot 230 .
- Knot 230 is first tied in free end 30 of suture 10 and pushed, in the direction of arrow 240 , through tissue 14 and against fixation member 18 , as shown in dashed line.
- knot 230 includes three crossing points, labeled, 230 a , 230 b, and 230 c .
- T When under tension, T, knot 230 tends to tighten upon itself, rather than slide in the direction of arrow 240 making it difficult to advance knot 230 along suture 10 .
- Knot pusher 250 is configured to keep suture at crossing points 230 a , 230 b, and 230 c from touching, such that knot 230 does not tighten upon itself under tension, T. This permits knot 230 to slide along the tensioned suture when knot pusher 250 is advanced in the direction of arrow 240 .
- Knot pusher 250 has a cylindrical body 252 and an end post 254 .
- Body 252 defines a first groove 254 and a second groove 256 on one surface, and a third groove 258 that is an extension of groove 256 on an opposite surface.
- Grooves 254 and 256 form and X pattern, and grooves 256 and 258 define a loop 260 extending around body 252 .
- the three grooves differ in depth, with groove 256 being the shallowest and groove 258 being the deepest.
- knot pusher 250 is removed by pulling retrograde on the knot pusher.
- a tube (not shown) can be advanced over knot pusher 250 between the knot pusher and the suture. As the tube is advanced past suture crossing point 230 a , the suture is stripped from knot pusher 250 .
- one or more additional fixation members 18 a with a slip knot 28 formed in suture 10 can be added to device 8 .
- fixation members 16 and 18 are implanted as described above, with suture 10 being tightened to secure fixation members 16 and 18 in place.
- Additional fixation member 18 a is then implanted and suture 10 tightened to secure fixation member 18 a in place.
- slot 110 in needle 100 of delivery device 99 is extended.
- additional fixation members 18 a preferably include a through bore (not shown) for passage therethrough by push rod 170 .
- Push rod 170 preferably is biased off angle such that when push rod 170 is pulled out of the passage in fixation member 18 a, the push rod is no longer aligned with the passage. Subsequent advancement of push rod 170 then engages an end face of fixation member 18 a to push the fixation member toward the tip of the needle 100 , rather than back through the passage. Slider 190 is preferably spring loaded such that after fixation member 18 is pushed out of needle 100 , push rod 170 springs back to engage the next fixation member 18 a.
- fixation member 16 and 18 in needle 100 can be swapped, with fixation member 18 located in distal region 112 such that fixation member 18 is implanted in the tissue prior to implantation of fixation member 16 .
- fixation member 18 is attached to fixation member 16 the same as the attachment to fixation member 18 , such that a second slip knot 28 a is formed and a second free end 30 a of suture extends from fixation member 16 .
- both ends 30 and 30 a of suture 10 are pulled.
- a suture 266 is attached to fixation members in the form of a first anchor member 270 and a second anchor member 272 .
- Members 270 , 272 are, for example, TAG WEDGE bone anchors available from Smith & Nephew, Inc. Endoscopy Division, Andover, Mass. Other bone anchors known in the art can be employed.
- Suture 266 has a first end 274 fixed to anchor member 270 , a second free end 276 , and a slip knot 268 , formed as described above for slip knot 28 .
- Suture 266 preferably passes through a separate suture loop 278 , rather than through 272 itself.
- Suture loop 278 acts as a good pulley allowing suture 266 to slide relative to suture loop 278 .
- the user forms bone holes 280 , 282 in bone 264 .
- the user implants anchor member 270 in bone hole 280 , with suture 266 already threaded as shown, followed by implanting anchor member 272 in bone hole 282 .
- the user then pulls on free end 276 of suture 266 , which brings soft tissue 262 against bone 264 .
- Slip knot 268 limits loosening of suture 266 .
- suture loop 278 suture 266 is not located within bone hole 282 in use thus limiting the possibility of trapping suture 266 against wall 284 of bone hole 282 . If suture 266 were trapped in bone hole 282 , pulling free end 276 of suture 266 would not result in shortening the length of suture between anchors 270 , 272 , which acts to secure soft tissue 262 against bone 264 .
- a wound closure device 1010 includes a first suture anchor 1012 , a second suture anchor 1014 , and a flexible member, e.g., suture 1016 that connects anchor 1012 to anchor 1014 .
- the suture is tied to the first anchor with a conventional knot, but movably attached to the second anchor, allowing a surgeon to shorten the length of suture between the anchors, and thereby close a wound.
- First anchor 1012 has a generally solid cylindrical body 1018 extending axially from a distal surface 1019 a to a flat proximal surface 1019 b.
- both an upper portion 1022 a and a lower portion 1022 b of surface 1019 a are beveled relative to the axis of cylindrical body 1018 , forming a rounded distal tip 1022 c.
- Upper portion 1022 a is beveled at an angle a relative to the axis of cylindrical body 1018
- lower portion 1022 b is beveled at an angle ⁇ relative to the axis.
- a fin-shaped projection 1020 that extends from upper portion 1022 a of distal surface 1019 a to proximal surface 1019 b.
- Fin 1020 defines two horizontally transverse holes, 1024 a and 1024 b.
- Suture 1016 is attached to first anchor 1012 by passing the suture through hole 1024 a in a first direction (e.g., out of the page in FIG. 16A), through hole 1024 b in a second direction (e.g., into the page in FIG. 16A), and then forming a conventional knot 1025 near fin 1020 .
- Conventional knot 1025 rigidly fixes suture 1016 to the first anchor.
- Second anchor 1014 has a distal surface 1029 a , a proximal surface 1029 b , and a generally cylindrical body 1028 extending axially from surface 1029 a to surface 1029 b. Attached to body 1028 is an appendage 1026 . Appendage 1026 is generally L-shaped in cross-section, and extends along an axial length of body 1028 , from surface 1029 a to surface 1029 b.
- Distal surface 1029 a of anchor 1014 is beveled in a manner similar to anchor 1012 : an upper portion 1031 a of surface 1029 a forms an angle ⁇ relative to an axis of body 1028 , and a lower portion 1031 b of surface 1029 a forms an angle ⁇ relative to the body's axis, forming a rounded distal tip 1031 c.
- Proximal surface 1029 b of anchor 1014 is flat.
- the L-shape of appendage 1026 is formed by two perpendicular sections: a stem 1036 attached to cylindrical body 1028 along an axial length of the body, and a base 1032 attached to the stem.
- Base 1032 defines a vertically transverse hole 1030
- stem 1036 defines two horizontally transverse holes 1034 a and 1034 b.
- Holes 1034 a and 1034 b are perpendicular to hole 1030 , but all three holes pass through anchor 1014 in a direction generally parallel to sides 1029 a and 1029 b.
- Each of the three holes 1034 a , 1034 b, and 1030 connect the exterior of anchor 1014 to an interior, partially enclosed, protected region 1039 .
- Region 1039 is defined by base 1032 , an interior surface 1037 of stem 1036 , and a concave groove 1035 within cylindrical body 1028 .
- Groove 1035 extends axially across body 1028 , along the line where interior surface 1037 connects to body 1028 .
- Suture 1016 is movably attached to second anchor 1014 with a one-way knot 1040 .
- One-way knot 1040 includes a first portion of suture 1016 that forms a loop 1042 , and a second portion of suture that passes around body 1028 and through the loop.
- Loop 1042 is formed within the protective region 1039 defined by groove 1035 , surface 1037 , and base 1032 . Region 1039 acts to separate loop 1042 from tissue when device 1010 is implanted within tissue, preventing the tissue from interfering with the sliding action of one-way knot 1040 .
- suture 1016 is first passed from an exterior of anchor 1014 , through hole 1034 a into region 1039 , and then back out hole 1034 b to the exterior, forming loop 1042 within region 1039 .
- the suture is then passed over the rounded, exterior surface 1041 of cylindrical body 1028 , back into region 1039 , through loop 1042 , and then to the exterior through hole 1030 .
- Suture 1016 terminates at a free end 1044 .
- One-way knot 1040 allows the length of suture between first anchor 1012 and second anchor 1014 to be shortened, but not lengthened. A surgeon can shorten the length of suture between the anchors by pulling on free end 1044 , which draws additional suture in the direction of the arrows in FIG. 16A, through holes 1030 , 1034 b , and 1034 a , thereby reducing the length of suture between anchors 1012 and 1014 .
- loop 1042 squeezes portion 1046 of suture 1016 against an interior compression surface 1043 of stem 1036 , preventing further lengthening of the distance between the anchors.
- suture 1016 is a braided suture, as opposed to a smooth suture, then suture 1016 should be threaded through second anchor 1014 in a particular direction.
- a braided suture 1016 a is formed from numerous threads 1017 a braided from left to right in FIG. 16D. Braided suture 1016 a slides more easily if it is pulled in the direction of braiding (i.e., in the direction of arrow S in FIG. 16D) than if it is pulled against the braiding (in the direction of arrow L).
- suture 1016 is a braided suture
- suture 1016 should be threaded through second anchor 1014 in the direction of braiding. If threaded in the direction of braiding, the suture will slide more easily in the direction of the arrows in FIG. 16A, and less easily in the direction opposing the arrows.
- cylindrical portions of anchors 1012 and 1014 are sized and shaped to fit within a hollow bore of a needle (described below), facilitating arthroscopic implantation of device 1010 .
- cylindrical body 1018 has a diameter D 1 of about 0.04 inches
- cylindrical body 1028 has a diameter D 2 approximately equal to diameter D 1 .
- Fin-shaped projection 1020 and L-shaped appendage 1026 are configured to protrude through a longitudinal slit in the needle. Delivery of device 1010 using a hollow needle is described below, with reference to FIGS. 20 A- 20 D and 21 A- 21 D.
- First anchor 1012 has an overall axial length L 1 of, e.g., about 0.19 inches, and fin 1020 has a height H 1 of, e.g., about 0.03 inches.
- Second anchor 1014 has an overall axial length L 2 of, e.g., about 0.22 inches, a width W 2 of, e.g., about 0.06 inches, and a height H 2 of, e.g., about 0.07 inches.
- Angle ⁇ is, e.g., about 30 degrees
- angle ⁇ is, e.g., about 40 degrees
- angle ⁇ is, e.g., about 30 degrees
- angle ⁇ is, e.g., about 40 degrees.
- Anchors 1012 and 1014 are made from rigid, biocompatible materials, such as polyethylene, an acetal, or polypropylene. Alternatively, the anchors can be made from resiliently deformable materials, as described in Hayhurst, supra, or from bioabsorbable materials. Anchors 1012 and 1014 are preferably unitary, injection molded pieces, but can also be manufactured by other methods.
- FIG. 17 illustrates the use of wound closure device 1010 to repair a torn meniscus 1050 .
- Meniscus 1050 is a C-shaped, rubbery, shock-absorbing structure located between the tibia and femur inside the knee.
- Meniscus 1050 has a tear 1052 that unnaturally separates distal meniscal tissue 1054 from proximal tissue 1056 .
- a width W M of meniscus 1050 as measured from points 1060 a and 1060 b to an exterior surface 1058 of the meniscus is, e.g., about 0.25 inches.
- both anchors 1012 and 1014 abut surface 1058 , separated by a distance of, e.g., about 1 cm.
- Suture 1016 passes from first anchor 1012 , into distal tissue 1054 , across tear 1052 , and emerges from proximal tissue 1056 at point 1060 a .
- Suture 1016 then passes again into proximal tissue 1056 at point 1060 b , again traverses tear 1052 , and emerges out surface 1058 , where it attaches to second anchor 1014 via one-way knot 1040 .
- suture 1016 passes again into distal tissue 1054 , traverses tear 1052 , and emerges from proximal tissue 1056 at or near point 1060 b . Free end 1044 of suture 1016 emerges from proximal tissue 1056 .
- FIGS. 17, 18A, and 18 B once device 1010 is implanted, a surgeon can close tear 1052 by pulling on free end 1044 of suture 1016 .
- free end 1044 When the surgeon pulls on free end 1044 , four separate movements occur in succession. First, friction between suture 1016 and body 1028 rotates second anchor 1014 until a lower surface 1033 of base 1032 is flush against meniscal surface 1058 , as shown in FIG. 18A.
- tension in suture 1016 pulls the center of fin 1020 towards surface 1058 , causing first anchor 1012 to align against surface 1058 transversely to the portion of suture 1016 that exits anchor 1012 , with both fin 1020 and the axial length of body 1018 pressing against meniscal surface 1058 .
- Third, continued pulling on free end 1044 draws additional suture through holes 1030 , 1034 b , and 1034 a , via knot 1040 , in the direction of the arrows of FIG. 16A, lengthening free end 1044 and shortening the length of suture between anchors 1012 and 1014 .
- second anchor 1014 When second anchor 1014 is in its final position, shown in FIG. 18B, suture 1016 is locked in place.
- the length of suture between anchors 1012 and 1014 cannot be increased, because loop 1042 of one-way knot 1040 presses portion 1046 of the suture against surface 1043 of stem 1036 .
- the length of suture between the anchors resists being further shortened, since portion 1062 of suture 1016 is wedged between body 1028 and surface 1058 of the meniscus.
- Wound closure device 1010 is preferably deployed within meniscus 1050 arthroscopically, using a hollow needle 1070 .
- hollow needle 1070 defines a bore 1072 and an open distal tip 1074 .
- the diameter DB of bore 1072 is slightly larger than diameter D 1 of body 1018 of first anchor 1012 , and diameter D 2 of body 1028 of second anchor 1014 , allowing body 1018 and body 1028 to fit slidably within the bore.
- Needle 1070 also includes a longitudinal slit 1076 through a wall of the needle. Slit 1076 extends proximally from open tip 1074 , and communicates with bore 1072 .
- Slit 1076 is sized and shaped to allow fin 1020 of first anchor 1012 and L-shaped appendage 1026 of second anchor 1014 to protrude from needle 1070 .
- Needle 1070 also includes a plunger 1080 .
- Plunger 1080 enters bore 1072 through a proximal opening 1082 in needle 1070 , and extends to proximal surface 1019 b of first anchor 1012 .
- Plunger 1080 passes by second anchor 1014 by sliding along groove 1035 .
- sliding plunger 1080 in the direction of arrow A pushes first anchor 1012 distally, but does not move second anchor 1014 .
- suture 1016 is attached to anchors 1012 and 1014 , in the manner described above with reference to FIG. 16A.
- the two anchors 1012 and 1014 are then loaded into bore 1072 of needle 1070 .
- Second anchor 1014 is loaded first, by inserting cylindrical head 1028 into bore 1072 , through open tip 1074 , such that appendage 1026 protrudes through slit 1076 .
- Second anchor 1014 is pushed proximally into slit 1076 , until stem 1036 abuts a proximal surface 1077 of the slit.
- first anchor 1012 is loaded into the distal most position in needle 1070 by inserting cylindrical body 1018 through tip 1074 , into bore 1072 , such that fin 1020 protrudes through slit 1076 .
- Both anchors 1012 and 1014 are loaded with their respective beveled distal surfaces 1019 a and 1029 a facing open distal tip 1074 .
- plunger 1080 is inserted into bore 1072 through proximal opening 1082 .
- Plunger 1080 is slid past second anchor 1014 along groove 1035 , until a tip 1084 of the plunger abuts proximal surface 1019 b of first anchor 1012 .
- Attachment of suture 1016 to anchors 1012 and 1014 and loading of the anchors and plunger into needle 1070 can be performed at the time of manufacture, i.e., pre-loaded, or immediately prior to surgery.
- the surgeon first pushes plunger 1080 in the direction of arrow A to separate anchors 1012 and 1014 within bore 1072 .
- the surgeon pushes the plunger until the anchors are separated by at least a distance L, as shown in FIG. 19, where L is greater than width W M of meniscus 1050 .
- Distance L is, e.g., about 0.35 inches.
- the surgeon next pushes needle 1070 through meniscus 1050 , in the direction of arrow A, until fin 1020 of first anchor 1012 passes entirely through exterior surface 1058 of the meniscus.
- the surgeon pushes needle 1070 through the tissue, he or she holds plunger 1080 steady, to prevent anchor 1012 from sliding in the direction of arrow B as the needle is pushed through the meniscal tissue. Since the separation distance L is greater than the width W M of meniscus 1050 , second anchor 1014 does not enter the meniscus at this point in the procedure.
- the surgeon next forces first anchor 1012 out of needle 1070 through tip 1074 by pushing plunger 1080 in the direction of arrow A, and then seats anchor 1012 against surface 1058 of the meniscus by pulling on free end 1044 of suture 1016 . Once anchor 1012 has been seated, needle 1070 is pulled in the direction of arrow B, back through meniscus 1050 , across tear 1052 , and out the hole at point 1060 a (FIG. 20B).
- Plunger 1080 and needle 1070 are then fully withdrawn in the direction of arrow B, leaving both anchors 1012 and 1014 resting against surface 1058 , as shown in FIG. 20D.
- the surgeon can then tension suture 1016 , positioning the anchors against surface 1058 and closing tear 1052 , by pulling on free end 1044 , as described above with reference to FIG. 17.
- device 1010 can be extracted from needle 1070 by engaging fin 1020 with surface 1058 , rather than by using a plunger 1080 .
- plunger 1080 is not passed through groove 1035 to first anchor 1012 . Instead, tip 1084 of plunger 1080 always remains proximal to anchor 1014 .
- Spacer 1086 is placed between the anchors.
- Spacer 1086 is a simple cylindrical bar, preferably made from a material that degrades quickly in the body, such as salt.
- Spacer 1086 has a longitudinal length L S greater than width W M of meniscus 1050 .
- Length L S is, e.g., about 0.35 inches.
- the surgeon next pulls the needle in the direction of arrow B, back through meniscus 1050 , across tear 1052 , and out the hole at point 1060 a (FIG. 21B).
- fin 1020 engages surface 1058 , and first anchor 1012 is pulled out of needle 1070 , through tip 1074 .
- the surgeon then seats anchor 1012 against surface 1058 by pulling on free end 1044 of suture 1016 . Since spacer 1086 is larger than width W M of meniscus 1050 , the spacer prevents second anchor 1014 from entering meniscus 1050 , and therefore prevents second anchor 1014 from also being pulled out of needle 1070 as needle 1070 is pulled in the direction of arrow B.
- a modified wound closure device is deployed in meniscus 1050 in reverse, second anchor first.
- a modified wound closure device includes a first anchor 1112 that has a beveled face 1119 a , but lacks a fin.
- Anchor 1112 has an axial, generally cylindrical body 1118 that defines two transverse holes 1124 a and 1124 b .
- Suture 1016 is attached to anchor 1112 by threading the suture through hole 1124 a in a first direction, through hole 1124 b in a second direction, and then tying a conventional knot 1125 .
- second anchor 1014 is positioned distally in bore 1072 , with first anchor 1112 directly proximal.
- Tip 1084 of plunger 1080 resides immediately proximal to first anchor 1112 in bore 1072 .
- the surgeon first pushes needle 1070 through meniscus 1050 , in the direction of arrow A, until tip 1074 passes through surface 1058 .
- the surgeon then pushes plunger 1080 in the direction of arrow A far enough to force second anchor 1014 through tip 1074 , but not far enough to eject first anchor 1112 .
- first anchor 1112 does not include a fin, it does not protrude through slit 1076 , and does not engage tissue when the needle is pulled in the direction of arrow B.
- the surgeon reinserts needle 1070 into the meniscus at point 1060 b , and again passes the needle through meniscus 1050 in the direction of arrow A, across tear 1052 , until tip 1074 passes through surface 1058 .
- the surgeon then ejects first anchor 1112 by pushing plunger 1080 in the direction of arrow A, (FIG. 22D), and withdraws needle 1070 from meniscus 1050 .
- the surgeon positions the anchors and closes tear 1052 by pulling on free end 1044 (FIG. 22E), as described above.
- suture 1016 can be threaded through second anchor 1014 so that the loop is located against an exterior surface 1637 of stem 1036 , rather than within region 1039 .
- suture 1016 is threaded through second anchor 1014 by first passing the suture around base 1032 , into region 1039 , and then out of region 1039 through hole 1034 a . The suture then passes back into region 1039 through hole 1034 b , forming a loop 1642 adjacent surface 1637 . After forming the loop, the suture passes through hole 1030 to the exterior, and then through loop 1642 , terminating at free end 1644 .
- second anchor 1214 has a structure similar to anchor 1014 , except that anchor 1214 lacks a base 1032 .
- Anchor 1214 includes a cylindrical body 1228 and a stem 1236 that define a wedge-shaped, partially enclosed region 1239 therebetween.
- Stem 1236 defines two holes, 1234 a and 1230 , and body 1228 defines one transverse hole 1234 b .
- Holes 1234 a and 1230 are generally parallel, and are both generally perpendicular to hole 1234 b .
- a suture 1216 passes from a first anchor (not shown) through hole 1234 a into region 1239 , and then through hole 1234 b to the exterior of the anchor, forming a loop 1242 within region 1239 .
- suture 1216 can wrap around body 1228 two or more times before passing back into region 1239 .
- second anchor 1314 includes a generally cylindrical body 1328 and an offset, generally rectangular appendage 1326 . Appendage 1326 and body 1328 define a partially protected region 1339 . As with anchor 1014 , a front surface 1329 a of anchor 1314 is beveled.
- Appendage 1326 defines three holes, 1330 , 1334 a , and 1334 b .
- Holes 1334 a and 1330 are generally straight, while hole 1334 b defines an arc through an inside of appendage 1326 .
- a suture 1316 passes from a first anchor (not shown) through straight hole 1334 a into region 1339 .
- Suture 1316 then passes out of region 1339 through arc-shaped hole 1334 b , forming a loop 1342 within region 1339 .
- the suture then wraps around a corner 1320 of body 1326 , passes through loop 1342 , and through hole 1330 , terminating at free end 1344 .
- second anchor 1414 includes a generally cylindrical body 1428 extending from a beveled distal surface 1429 a to a flat proximal surface 1429 b.
- a generally rectangular appendage 1426 also extends from surface 1429 a to surface 1429 b.
- Rectangular appendage 1426 is attached to body 1428 along the long side of the rectangle, and is centered along an axial length of body 1428 .
- Body 1428 and appendage 1426 define a protected region 1439 .
- Appendage 1426 defines two holes, 1434 a and 1430 , and body 1428 defines two transverse holes, 1434 b and 1434 c.
- Hole 1434 b is located entirely within body 1428
- hole 1434 c is located at a juncture 1492 between body 1428 and appendage 1426 .
- Holes 1434 a and 1430 are generally parallel, and are both generally perpendicular to holes 1434 b and 1434 c.
- a suture 1416 extends from a first anchor (not shown), through hole 1434 a into region 1439 , and then out of region 1439 through hole 1434 b , forming a loop 1442 within region 1439 .
- the suture then passes back into region 1439 through hole 1434 c, through loop 1442 , and out of region 1439 through hole 1430 , terminating at free end 1444 .
- second anchor 1514 includes a generally cylindrical body 1528 and an appendage 1526 . Both body 1528 and appendage 1526 extend from a beveled distal surface 1529 a to a flat proximal surface 1529 b.
- Appendage 1526 includes a stem 1536 attached to body 1528 , and a head 1532 attached to stem 1536 .
- Stem 1536 is rectangular in cross-section and head 1532 is D-shaped in cross-section, giving appendage 1526 a mushroom-shaped cross-section.
- Stem 1536 , head 1532 , and body 1528 define a partially enclosed, protected region 1539 .
- Stem 1536 defines two transverse holes 1534 a and 1534 b , and body 1528 defines a single transverse hole 1530 located at a juncture 1592 between body 1528 and stem 1536 .
- a suture 1516 passes from a first anchor (not shown), through hole 1534 a into protected region 1539 , and then out of region 1539 through hole 1534 b , forming a loop 1542 within region 1539 .
- Suture 1516 then passes around D-shaped head 1532 through a transverse groove 1594 in head 1532 , back into region 1539 , through loop 1542 , and out hole 1530 , terminating at free end 1544 .
- the second anchor can have a T shape or a crescent shape, and can be deployed at a surface of the meniscus or inter-body.
- second anchor 1730 has a T-shape.
- the base 1732 of the T defines three through-holes, 1734 a , 1734 b , and 1734 c , and the stem 1736 of the T is configured to penetrate meniscal tissue.
- Stem 1736 is offset from base 1732 so that the stem does not block hole 1734 b .
- second anchor 1814 has a flat, generally circular proximal surface 1836 , and a rounded distal surface 1838 , giving the anchor a generally hemispherical or “crescent” shape. (Alternatively, surface 1836 can be concave.)
- Anchor 1814 defines three through-holes, 1830 , 1834 a , and 1834 b . The holes pass in an axial direction from the anchor's proximal circular surface 1836 to its distal rounded surface 1838 .
- FIG. 29 illustrates deployment of a device 1810 that has a crescent-shaped second anchor 1814 , and a “pulley” anchor 1813 .
- Pulley anchor 1813 does not act as a dead-end for a suture, nor does it include a one-way knot. Instead, pulley anchor 1813 includes two through-holes, 1824 a and 1824 b .
- a suture 1816 passes through hole 1824 a in a first direction, and then through hole 1824 b in a second direction, such that suture 1816 can slide over pulley anchor 1813 in either direction.
- Pulley anchor 1813 can have the shape and structure of anchor 1012 (i.e., the holes are located on a fin), the simple cylindrical structure of anchor 1112 of FIG. 22A, or numerous other structures.
- anchors 1813 and 1814 are deployed using, e.g., a hollow needle 1070 , such that anchor 1814 is positioned on a proximal side of meniscus 1050 , and anchor 1813 is deployed against distal surface 1058 .
- suture 1816 passes through hole 1834 a of crescent-shaped anchor 1814 in a generally proximal direction (arrow P), from rounded surface 1838 to circular surface 1836 , and then through hole 1834 b in a generally distal direction (arrow D), forming a loop 1842 .
- suture 1816 From loop 1842 , the suture passes through meniscal tissue, through hole 1824 a of pulley anchor 1813 , through hole 1824 b of anchor 1813 , and back through meniscal tissue to the crescent shaped anchor. The suture then passes through loop 1842 , terminating at free end 1844 .
- the opposite end 1845 of suture 1816 includes a knob or a knot 1847 that prevents end 1845 from passing through hole 1834 a .
- suture 1816 begins at anchor 1814 , in addition to forming the one-way knot at anchor 1814 .
- a device 1811 includes a first anchor 1012 and crescent-shaped second anchor 1814 .
- Suture 1816 passes through holes 1024 a and 1024 b of anchor 1012 , forming a knot 1025 as shown in FIG. 16A.
- suture 1816 passes through meniscal tissue and then through holes 1834 a and 1834 b of anchor 1814 , forming loop 1842 .
- loop 1842 the suture passes back through meniscal tissue to first anchor 1012 , and then through a fixed loop 1843 located between knot 1025 and first anchor 1012 .
- the suture then passes back through meniscal tissue, through hole 1830 of anchor 1814 , and through loop 1842 , terminating at free end 1844 .
- the crescent shaped anchor 1814 of device 1810 can be deployed inter-body (i.e., embedded within meniscal tissue), rather than against a surface of the meniscus.
- device 1810 is deployed in the manner described above with reference to FIG. 29, or using another deployment method.
- the surgeon pushes anchor 1814 into the meniscal tissue, using, e.g., a needle.
- a point 1817 of anchor 1814 can be sharp.
- second anchors described herein whether or not they include a sharp point, can also be positioned inter-body.
- the one-way knot can be left “loose” until after both the first and second anchors are positioned against the meniscus.
- the suture would be very long, e.g., more than 12 cm long, such that the one-way knot includes considerable slack, and the loop portion of the knot is accessible to the surgeon's fingers.
- the surgeon can position the first and second anchors against backside 1058 by pulling on both the free end and the loop itself. Once the anchors are satisfactorily positioned, the surgeon tightens the knot by pulling on the free end.
- the second anchor can employ one-way tightening schemes other than a “one-way knot.”
- a device 1650 includes first anchor 1012 , a second anchor 1652 , and two sutures 1616 and 1654 .
- Second anchor 1652 has a generally cylindrical shape, and defines two through-holes 1656 and 1658 .
- suture 1616 passes from first anchor 1012 , through holes 1060 a and 1060 b in the meniscus, and then through holes 1656 and 1658 of anchor 1652 , terminating at free end 1660 .
- Suture 1616 does not form a one-way knot at second anchor 1652 . Instead, suture 1616 simply passes through holes 1656 and 1658 in succession, such that anchor 1652 acts as a pulley anchor.
- the second suture, suture 1654 passes only through hole 1656 of anchor 1652 , and through hole 1060 b of the meniscus.
- a portion 1662 of suture 1654 , distal to hole 1656 is thicker than the remainder of suture 1654 . This thicker portion 1662 cannot pass through hole 1656 . (The thickness of portion 1662 is exaggerated in FIG. 32.)
- a surgeon deploys the two anchors as described above with respect to other embodiments, and then pulls on free end 1660 of suture 1616 to position the anchors against backside 1058 and close the tear in the meniscus.
- suture 1616 is tensioned to the surgeon's satisfaction, the surgeon pulls on suture 1654 in the proximal direction (arrow P), until a segment of portion 1662 wedges into hole 1656 .
- Portion 1662 wedges suture 1616 in place within hole 1656 , preventing the length of suture 1616 between the two anchors from increasing, and thereby locking the two anchors in place.
- the fin-shaped projection 1020 of the first anchor need not have the shape shown in the figures.
- Other types of projections capable of protruding through a needle opening and engaging tissue can be used.
- the first anchor need not include any projection, but can instead be a simple cylinder defining holes for affixation of the suture.
- the suture can be welded or glued to the anchor, or can be spliced.
- the first anchor need not include an extended, cylindrical body, but can instead have a button-shaped body.
- Button-shaped first anchor 1712 includes a circular distal side 1719 a and a circular proximal side 1719 b .
- Two axial holes 1724 a and 1724 b pass from side 1719 a to side 1719 b .
- a suture 1716 is attached to anchor 1712 by passing through hole 1724 a in a first direction, through hole 1724 b in a second direction, and then forming a conventional knot 1725 on the distal side of the anchor.
- button-shaped first anchor 1712 is deployed against a proximal surface 1796 of meniscus 1050
- second anchor 1014 is deployed against surface 1058 .
- Suture 1716 passes from first anchor 1712 into proximal tissue 1056 at point 1760 , such that knot 1725 is located within the tissue. From point 1760 , suture 1716 passes across tear 1052 to second anchor 1014 , then through second anchor 1014 in the manner described above with reference to FIG. 16. From second anchor 1014 , the suture passes back into distal tissue 1054 , across tear 1052 , and emerges from proximal tissue 1056 at point 1760 . The suture then terminates at free end 1744 . As with the embodiments described above, pulling on free end 1744 tensions the suture and closes the tear.
- button-shaped anchor 1712 can be deployed on the distal side of the tear adjacent second anchor 1014 , using the methods described above with reference to FIGS. 17 , 20 A- 20 D, 21 A- 21 D, and 22 A- 22 D.
- the second anchor need not include a groove 1035 to allow passage of a plunger. Instead, the second anchor can define an axial through-hole for passage of the plunger.
- the first and second anchors can be connected with other types of flexible members.
- the wound closure device can include more than two suture anchors.
- the device in addition to the first and second anchors, can include a third anchor identical in structure and function to the second anchor.
- the surgeon could again pass the suture across tear 1052 , adding an additional stitch, and then deploy the third anchor against surface 1058 .
- the surgeon would pull on the free end of the suture, causing the suture to slide over both the second and third anchors, shortening the length of suture between the third and first anchors, and thereby closing the wound.
- one or more of the anchors can be a pulley, such as pulley anchor 1813 described above with reference to FIG. 29.
- the device could include a first anchor 1012 , a pulley anchor 1813 , and a second anchor 1014 .
- the suture would be affixed to the first anchor, would slide over the pulley anchor, and form a one-way knot at the second anchor.
- the additional anchors can all be pulley anchors, can all be similar to the second anchor, or can be both additional pulleys and additional second anchors.
- the wound closure devices need not be deployed using a needle, and need not be deployed arthroscopically. Instead, a surgeon can place the anchors against the tissue during an open procedure.
- the wound closure devices can be used to repair tissue wounds other than meniscal tears.
- the devices can be used to repair tears in skin, muscles, and ligaments, and to re-attach tissue to support structures, such as bones.
- a device 308 for repairing a tear 12 in tissue 14 includes a suture 310 attached to a single fixation member 326 .
- Fixation member 326 defines through holes 330 , 332 for receiving suture 310 .
- Suture 310 has a first end 312 attached to suture 310 at point 314 (as described above with reference to FIG. 2B) to form a looped end 316 remote from fixation member 326 , and a second, free end 334 .
- fixation member 326 When implanted in the knee joint, fixation member 326 lies on a surface 20 of tissue 14 . Looped end 316 is located in tear 12 and extends along surface 26 of tissue 14 . Suture 310 extends through tissue 14 , passing through looped end 316 in tear 12 , and emerging at tissue surface 20 where suture 310 loops through fixation member 326 . Suture 310 extends back through tissue 14 , passing through looped end 316 in tear 12 and through a slip knot 321 formed in suture 310 , and emerging at tissue surface 26 .
- a delivery device 399 for implanting device 308 includes a suture holder 400 and needle 460 .
- Suture holder 400 includes a tube 410 defining a lumen 415 through which needle 460 extends, a shaft 420 , and a distal portion 430 .
- Distal portion 430 has a first tine 440 defining grooves 445 and 446 , and a second tine 450 defining grooves 455 , 456 .
- Needle 460 has a beveled tip 461 and a slot 462 in a top portion 463 of needle 460 .
- fastening member 326 with attached suture 310 is positioned in slot 462 with suture 310 preformed with looped end 316 and slip knot 321 .
- Slip knot 321 is formed as described above with reference to FIGS. 2 A- 2 I, though where fixation member 16 is positioned in FIGS. 2 A- 2 I, suture 310 is formed as looped end 316 (FIG. 37C). Looped end 316 is positioned on suture holder 400 within grooves 445 , 446 , 455 and 456 of tines 440 , 450 (FIG. 37B), and extends along a bottom side 480 of shaft 420 .
- delivery device 399 includes a handle 451 with a push knob 453 for advancing needle 460 relative to suture holder 400 .
- the user inserts distal portion 430 of suture holder 400 into tear 12 of tissue 14 , and then advances needle 460 through tissue 14 , traversing tear 12 , and exiting tissue 14 at tissue surface 20 .
- Needle 460 passes between tines 440 and 450 , and thus through looped end 316 of suture 310 (FIG. 39).
- the user then retracts needle 460 from tissue 14 (FIG. 40).
- the contact of fastening member 326 with tissue surface 20 during the retraction of needle 460 acts to push fastening member 326 out of needle 460 such that fastening member 326 remains at surface 20 , as described above with reference to FIG. 7.
- Pulling on free end 334 of suture 310 brings sides 22 , 24 of tear 12 into juxtaposition. Slip knot 321 secures device 308 in place. Excess suture 310 can then be cut off.
- suture 310 includes a retaining element in the form of a Chinese trap or hand cuff 495 , that is, an element that when pulled on, tightens around something disposed within the element. Free end 334 of suture 310 is slidably received within trap 495 . When free end 334 of suture 310 is pulled in the direction of arrow 520 trap 495 is stretched, eventually gripping suture passing therethrough to secure suture 310 and device 308 .
- the retaining element can also take the form of retaining elements described above with reference to FIGS. 12 - 12 C and 13 .
- a device 799 for repairing tear 12 in tissue 14 includes a barbed fastening member 800 and a suture 820 .
- Suture 820 has an end 810 attached to fastening member 800 .
- Suture 820 is formed in loop 830 with a second end 832 of suture 820 attached to suture 820 .
- Delivery device 399 can be used to deploy device 799 with suture 820 being tightened to close tear 12 by pushing fastening member 800 in the direction of arrow 840 , rather than pulling on a free end of suture.
- Barbed fastening member 800 limits loosening of suture 820 .
- an alternative embodiment of a fixation member 600 includes through bores 610 , 620 with radiused comers 615 to reduce friction between suture 470 and fixation member 600 .
- another embodiment of a fixation member 650 which can be used in any of the above embodiments, includes a solid rod 660 with ends 680 , 690 , and a braided suture 670 attached to ends 680 , 690 .
- Suture 670 forms a loop 700 for receiving suture 10 or suture 310 . Loop 700 lines up with suture 10 , 310 to act as a pulley and reducing friction between the suture and fixation member.
- fixation members, securement elements, and suture of the above embodiments can be formed of a biodegradable material.
Abstract
A method of closing a tissue wound includes providing a wound closure device having a first anchor, a second anchor, and a flexible member movably attached to the second anchor, positioning the first anchor against tissue, passing the flexible member across the wound, positioning the second anchor against tissue, and pulling on a free end of the flexible member to shorten a length of the flexible member between the first and second anchors, thereby closing the wound. A wound closure device includes a first anchor, a second anchor; and a flexible member connecting the first anchor to the second anchor, the flexible member being movably attached to the second anchor, such that pulling on a free end of the flexible member shortens a length of the flexible member between the first and second anchors.
Description
- This application is a continuation of co-pending U.S. application Ser. No. 09/704,926, filed Nov. 2, 2000, entitled CLOSURE DEVICE FOR AND METHOD FOR TISSUE REPAIR, and a continuation-in-part of co-pending U.S. application Ser. No. 09/453,120, filed Dec. 2, 1999, entitled WOUND CLOSURE DEVICES AND METHODS.
- The invention relates to a closure device and method for tissue repair.
- Fibrous tissue wounds, such as muscle, ligament, and cartilage tears, can be repaired arthroscopically using sutures. Traditionally, to close a fibrous tissue wound, a surgeon would insert two suture needles into the tissue with sutures attached, thread the sutures across the wound, and then tie knots to fix the free ends of the sutures within the tissue.
- To simplify the wound closure procedure and to improve fixation, various types of suture anchors have been developed. One example of a suture anchor is disclosed in Hayhurst, U.S. Pat. No. 4,741,330, which is incorporated herein by reference. In Hayhurst, one end of a suture is fixed to a resiliently-deformable, bar-shaped suture anchor. The anchor is loaded into the bore of a hollow needle and deployed into or against the fibrous tissue. The surgeon then threads the suture across the wound and tensions a free end of the suture to pull the wound closed. When the surgeon tensions the suture, the bar in the anchor becomes oriented transversely to the suture hole, anchoring the suture in place.
- According to one aspect of the invention, in general, the invention features a wound closure device that includes a first anchor, a second anchor, and a flexible member that connects the first anchor to the second anchor. The flexible member is movably attached to the second anchor, such that pulling on a free end of the flexible member shortens a length of the flexible member between the first and second anchors.
- Embodiments of this aspect of the invention may include one or more of the following features.
- The movable attachment of the flexible member to the second anchor allows the length of the flexible member between the first and second anchors to be shortened, but not lengthened.
- The movable attachment can be a knot formed in the flexible member at the second anchor. The knot includes, e.g., a first portion of the flexible member that forms a loop, and a second portion (which might include the free end) that passes over a surface of the second anchor and through the loop. The surface can be, e.g., an exterior surface of the second anchor.
- Pulling on the free end of the flexible member in one direction causes the flexible member to slide through the loop, but pulling on the flexible member in an opposite direction causes the loop to press the second portion against a compression surface of the second anchor, resisting increase in the length of the flexible member between the first and second anchors. The loop can be disposed within a partially enclosed region of the second anchor.
- The second anchor can include a first section that defines a plurality of holes through which the first portion of the flexible member passes to form the loop. A second section of the second anchor defines a passage that connects to the partially enclosed region, and the free end of the suture passes through this passage.
- The second anchor can include a rounded body and an appendage attached to the rounded body, where the rounded body and the appendage define a partially enclosed region therebetween. At least a portion of the flexible member passes through the partially enclosed region. In addition, the flexible member might wrap around the rounded body.
- The rounded body can have a generally cylindrical shape, sized to fit within the bore of a hollow needle, and an axial groove. The groove extends across an axial length of the rounded body. The cross-sectional shape of the rounded body can be, e.g., a rectangle, an L, or a D.
- The second anchor can also have a generally hemispherical shape, a generally crescent shape, or a T-shape. The crescent-shaped anchor can have sharp tip configured to penetrate tissue.
- The second anchor defines a through-hole through which the flexible member passes. In addition, the device can also include a second flexible member that passes through the through-hole, where the second flexible member has a thickened portion that has a width greater than a width of the through-hole, such that the thickened portion cannot pass through the through-hole.
- The first anchor includes, e.g., a generally cylindrical body sized and shaped to fit within the bore of a hollow needle, and a projection, such as a longitudinal fin, extending from the cylindrical body. Alternatively, the first anchor can have a button shape. The first anchor can define a hole for passage of the flexible member therethrough, and the flexible member can be fixed to the first anchor.
- The flexible member can be a suture.
- The wound closure device further includes a retaining element coupled to the flexible member. The retaining element is slidably received by the flexible member and acts to limit loosening of the flexible member relative to the second fixation member. Alternatively, the retaining element is movable relative to the second fixation member and acts to limit loosening of the flexible member relative to the second fixation member.
- In another aspect, the invention features a wound closure kit that includes an open-tipped needle and first and second anchors connected by a flexible member disposed within a bore of the needle.
- Embodiments of this aspect of the invention may include one or more of the following features.
- The needle can define a longitudinal slit, and the first anchor can include a projection that protrudes through the slit. The second anchor can also include an appendage that protrudes through the slit, and the flexible member can be attached to the appendage. The flexible member can be fixed to the first anchor, but movably attached to the second anchor.
- In another aspect, the invention features a method of closing a tissue wound. The method includes: (a) providing a wound closure device that has a first anchor, a second anchor, and a flexible member movably attached to the second anchor; (b) positioning the first anchor against tissue; (c) passing the flexible member across the wound; (d) positioning the second anchor against tissue; and (e) pulling on a free end of the flexible member to shorten a length of the flexible member between the first and second anchors, thereby closing the wound.
- This aspect of the invention may include one or more of the following features.
- The flexible member can be slidably attached to the second anchor by a one-way knot, such that after completion of the pulling step, the length of the flexible member between the first and second anchors remains shortened. Part of the one-way knot can be disposed within a partially enclosed region of the second anchor. The partially enclosed region can be located such that during the pulling step, the portion of the one-way knot disposed within the partially enclosed region avoids contact with tissue.
- The first positioning step can include positioning the first anchor on a first side of the wound. The passing step can include passing the flexible member from the first side to a second side of the wound, engaging tissue on the second side, and returning the flexible member to the first side. The second positioning step can include positioning the second anchor on the first side of the wound.
- The first and second anchors can initially be disposed, at least partially, within the bore of a hollow, open-tipped needle. The first anchor can include a section that protrudes through a slit in the needle, and the first positioning step can include engaging the projection with tissue to remove the first anchor from the bore.
- The providing step can include providing a device in which the flexible member passes through a through-hole in the second anchor, and the device further includes a second flexible member that also passes through the through-hole. The second flexible member has a thickened portion that is wider than the through hole. The method further includes pulling the second flexible member until the thickened portion wedges into the through hole.
- In another aspect, the invention features a method of repairing a tear in a meniscus. The method includes: (a) providing a tear closing device having a first anchor, a second anchor, and a flexible member movably attached to the second anchor; (b) positioning the first anchor against the meniscus; (c) passing the flexible member across the tear; (d) positioning the second anchor against the meniscus; and (e) pulling on a free end of the flexible member to shorten a length of the flexible member between the first and second anchors, thereby closing the tear.
- Embodiments of this aspect of the invention can include one or more of the following features.
- The first positioning step can include positioning the first anchor against an external surface of the meniscus, on a first side of the tear, the passing step can include passing the flexible member from the first side to a second side of the tear, engaging tissue on the second side, and returning the flexible member to the first side, and the second positioning step can include positioning the second anchor against the external surface. Alternatively, the first and second anchors can be positioned against external surfaces of the meniscus on opposite sides of the tear.
- According to another aspect of the invention, a surgical method includes positioning a fixation member relative to tissue, moving a flexible member coupled to the fixation member relative to the fixation member to bring two tissue surfaces together, and moving a retaining element coupled to the flexible member relative to the fixation member. The retaining element acts to limit loosening of the flexible member relative to the fixation member.
- Embodiments of this aspect of the invention may include one or more of the following features.
- The step of moving the flexible member comprises pulling the flexible member. The step of moving the flexible member also accomplishes the step of moving the retaining element, which is, for example, a slip knot. Alternatively, the step of moving the retaining element includes moving the retaining element relative to the flexible element. The retaining element is, for example, a friction element which permits sliding of the retaining element relative to the flexible element in only one direction. In another illustrated embodiment the retaining element is in the form of an overhand knot, and the method includes advancing the overhand knot along the flexible element. In another illustrated embodiment, the retaining element is in the form of a Chinese trap.
- In an exemplary embodiment, the step of moving the flexible member includes pulling on only one end of the flexible member.
- In another illustrated embodiment, the method includes positioning a second fixation member relative to the tissue. The second fixation member is coupled to the flexible member, either movably or fixedly. The step of moving the flexible member includes, for example, pulling on two ends of the flexible member or pulling on only one end of the flexible member.
- The step of positioning the fixation member includes positioning the fixation member on an outer surface of the tissue, and the two tissue surfaces brought together are both soft tissue. Alternatively, the fixation member is positioned in a bone hole, and one of the two tissue surfaces brought together is bone and the other soft tissue.
- In another illustrated embodiment, the step of positioning the fixation member includes passing the fixation member through a loop of the flexible member. The loop is positioned within a tear in soft tissue.
- According to another aspect of the invention, a method for repairing a tear in soft tissue includes advancing a fixation member coupled to a flexible member through tissue on either side of the tear and through a loop of the flexible member, and tensioning the flexible member to bring two tissue surfaces on either side of the tear together.
- Embodiments of this aspect of the invention may include one or more of the following features. The loop is positioned within the tear. The method includes pulling an end of the flexible member to bring the two tissue surfaces together. The fixation member is in the form of a barbed member.
- According to another aspect of the invention, an apparatus for repairing a tear in soft tissue includes at least two fixation members, a flexible member substantially immovably secured to the first fixation member and movably coupled to the second fixation member, and a retaining element coupled to the flexible member. The retaining element is movable relative to the second fixation member and acts to limit loosening of the flexible member relative to the fixation member.
- According to another aspect of the invention, an apparatus for repairing a tear in soft tissue includes at least two fixation members, a flexible member substantially immovably secured to the first fixation member and movably coupled to the second fixation member, and a retaining element coupled to the flexible member. The retaining element is slidably received by the flexible member and acts to limit loosening of the flexible member relative to the fixation member.
- According to another aspect of the invention, an apparatus for repairing a tear in soft tissue includes a fixation member, and a flexible member movably coupled to the fixation member. A first end of the flexible member is looped back and secured to the flexible member to form a loop. The loop is remote from the fixation member.
- According to another aspect of the invention, a flexible member holder includes a shaft, a first tine at an end region of the shaft defining a first region for receiving a first portion of a loop of a flexible member, and a second tine at the end region of the shaft defining a second region for receiving a second portion of the loop of the flexible member.
- Embodiments of this aspect of the invention may include one or more of the following features. The shaft is a tube. The first and second regions are grooves.
- According to another aspect of the invention, a device for repairing a tear in a tissue includes a needle having a distal region defined between two holding elements, and a proximal region. A first fixation member is positioned within the distal region and a second fixation member is positioned within the proximal region. A flexible member is coupled to the first and second fixation members.
- Embodiments of this aspect of the invention may include one or more of the following features. A first of the holding elements is a crimp in the needle in the distal region, and the second holding element is a dimple or ramp extending into a lumen of the needle. The needle wall has a slot and the fixation members extend through the slot. The needle is sized to fit into an end of a protector tube. A push pin is sized to fit inside the needle.
- Embodiments of the invention may include one or more of the following advantages. The first and second anchors can be deployed using a single hollow needle, rather than two separate needles. After deploying a fixation member or anchor, the surgeon need not tie an additional knot. The length of a flexible member coupled to the fixation member can be adjusted after deploying the fixation member, allowing a surgeon to set the tension in the flexible member to a desired level. The length of a flexible member spanning across a tear in tissue can be shortened to close the tear by tensioning the flexible member with no additional manipulation being required to limit loosening of the flexible member.
- Since the device uses a flexible member, such as a suture, to close the tissue wound, rather than inflexible staples or tacks, the tissue is not significantly damaged when it expands and contracts. For example, if the soft tissue is a meniscus, the fixation members do not damage the meniscal tissue when the knee moves.
- The details of one or more embodiments of the invention are set forth in the accompanying drawings and the description below. Other features, objects, and advantages of the invention will be apparent form the description and drawings, and from the claims.
- FIG. 1 is an illustration of a closure device according to the invention, shown mending a tear in soft tissue;
- FIGS.2A-2I show a method of tying a slip knot in suture of the closure device of FIG. 1;
- FIG. 3 is a perspective view of a delivery device for inserting the closure device of FIG. 1 into soft tissue;
- FIG. 4 is a perspective view of the delivery device of FIG. 3 shown with an outer sheath removed;
- FIG. 4A is a perspective view of a fixation member of the closure device of FIG. 1;
- FIG. 4B is a cross-sectional end view of the delivery device of FIG. 4, taken along lines19B-19B;
- FIG. 4C is a cross-sectional side view of an alternative embodiment of a needle of the delivery device of FIG. 3;
- FIG. 5 is side view of the delivery device of FIG. 3;
- FIG. 5A is a side view of a variable length depth stop for use with the delivery device of FIG. 3;
- FIG. 5B is a perspective view of a cannula for use with the delivery device of FIG. 3;
- FIGS.6-11 show the delivery device in use inserting the closure device of FIG. 1 in soft tissue, with FIG. 7 being an exploded view of
region 7 of FIG. 6; - FIG. 12 is an illustration of the closure device of FIG. 1 with an alternative embodiment of a retaining element, shown mending a tear in soft tissue;
- FIGS. 12A and 12B show alternative embodiments of the retaining element of FIG. 11;
- FIG. 12C shows the retaining element of FIG. 12 in an alternative position;
- FIG. 13 shows an additional alternative embodiment of a retaining element in the form of an overhand knot;
- FIGS. 13A and 13B show an overhand knot and a knot pusher for advancing the overhand knot of FIG. 13;
- FIG. 14 is an illustration of an alternative embodiment of a closure device;
- FIG. 14A shows an alternative arrangement of the closure device and delivery device of FIG. 14;
- FIG. 14B is an illustration of an alternative embodiment of a closure device;
- FIG. 15 is an illustration of an alternative embodiment of a closure device for use in attaching soft tissue to bone;
- FIG. 16A is a perspective view of a wound closure device;
- FIG. 16B is a side view of a first suture anchor of the wound closure device of FIG. 16A;
- FIG. 16C is a side view of a second suture anchor of the device of FIG. 16A;
- FIG. 16D is an enlarged view of a braided suture;
- FIG. 17 is a perspective, cut-away view of the wound closure device of FIG. 17A implanted within a meniscus;
- FIGS. 18A and 18B are sectional views of the second suture anchor and one-way knot of the wound closure device of FIG. 16A;
- FIG. 19 is a perspective view of a hollow needle, with the wound closure device of FIG. 16A disposed within a bore of the needle;
- FIGS.20A-20D are schematics illustrating deployment of the wound closure device of FIG. 16A into a meniscus using a plunger;
- FIGS.21A-21D are schematics illustrating deployment of the wound closure device of FIG. 16A into a meniscus using a plunger and a spacer;
- FIG. 22A is a perspective view of an alternative first anchor design for a wound closure device, used in reverse deployment of the device;
- FIGS.22B-22E are schematics illustrating reverse deployment of a wound closure device;
- FIGS. 23A and 23B are perspective views of the second suture anchor of FIGS. 16A and 16C, showing an alternative one-way knot configuration for the anchor;
- FIGS.24-27 are sectional views of alternative configurations of the suture anchor and one-way knot of FIGS. 18A and 18B;
- FIG. 28A is a top view of a T-shaped second suture anchor;
- FIG. 28B is a side view of the T-shaped suture anchor of FIG. 28A;
- FIG. 28C is a front view of a crescent-shaped second suture anchor;
- FIG. 28D is a side view of the crescent-shaped suture anchor of FIG. 13C;
- FIGS.29-31 are sectional views showing deployment of wound closure devices that include the crescent-shaped suture anchor of FIG. 28C;
- FIG. 32 is a perspective, partially schematic view of an alternative wound closure device implanted within a meniscus;
- FIG. 33A is a perspective view of an alternative first suture anchor design for a wound closure device;
- FIG. 33B is a perspective, cut-away view of the wound closure device of FIG. 33A implanted within a meniscus;
- FIG. 34 is a cross-sectional side view of an alternative embodiment of a closure device, shown mending a tear in soft tissue;
- FIG. 35 shows the closure device of FIG. 34 in use prior to securing the closure device in place;
- FIG. 36 is a top view of the closure device of FIG. 34, shown after securing the closure device in place;
- FIG. 37 is a side view of a delivery device for inserting the closure device of FIG. 34 in soft tissue;
- FIG. 37A is a perspective view of a distal section of the delivery device of FIG. 37 shown with a fixation member of the closure device of FIG. 34;
- FIG. 37B is a perspective view similar to that of FIG. 37A shown with the closure device of FIG. 34;
- FIG. 37C is an illustration of the closure device of FIG. 34;
- FIGS.38-40 show the delivery device of FIG. 37 in use inserting the closure device of FIG. 34 in soft tissue;
- FIG. 41 is a cross-sectional side view of the closure device of FIG. 34 with an alternative embodiment of a retaining element, shown mending a tear in soft tissue;
- FIG. 42 is a cross-sectional side view of an alternative embodiment of a closure device, similar in use to the closure device of FIG. 34; and
- FIGS. 43 and 44 are alternative embodiments of a fixation member of the closure device of FIG. 34.
- Referring to FIG. 1, a
closure device 8 for mending atear 12 insoft tissue 14, e.g., meniscus of the knee joint, includes a flexible member, e.g.,suture 10, coupled to afirst fixation member 16 and asecond fixation member 18.Suture 10 is fastened tofixation member 16 to limit movement ofsuture 10 relative tofixation member 16, whilesuture 10 is movable relative tofixation member 18. - When implanted in the knee joint,
fixation members surface 20 oftissue 14, for example, the outer surface of the meniscus.Suture 10 has a first suture length 10 a extending fromfirst fixation member 16 throughtissue 14, traversingtear 12, and emerging at asurface 26 oftissue 14; a second suture length 10 b extending acrosssurface 26; a third suture length 10 c extending back throughtissue 14, traversingtear 12 at a location spaced from first length 10 a, and emerging attissue surface 20 wheresuture 10 loops throughsecond fixation member 18; and afourth suture length 10 d extending fromsecond fixation member 18 throughtissue 14, traversingtear 12, and emerging atsurface 26.Suture 10 has afree end 30 which the surgeon pulls, in the direction ofarrow 32, to bringsides tear 12 together into juxtaposition (as shown in FIG. 10). - As described further below, suture portion10 c and
suture portion 10 d are tied together prior to implantation ofdevice 8 to form a retaining element in the form of aslip knot 28 that allowssuture 10 to be pulled in the direction ofarrow 32, but does not allow tension onsuture 10 to pullsuture 10 in the opposite direction, which would allowtear 12 to re-open. - Referring to FIGS.2A-2I, prior to insertion into
tissue 14,suture 10 is attached tofixation members slip knot 28 is formed.Fixation member 16 defines holes 16 a, 16 b for receivingsuture 10, andfixation member 18 definesholes 18 a, 18 b for receivingsuture 10. As illustrated in FIGS. 2A-2D,suture 10 is attached tofixation member 16 by threadingsuture 10 through aneedle 50, and passingneedle 50 andsuture 10 through holes 16 a, 16 b in fixation member 16 (FIG. 2A).Suture 10 now defines along suture section 52 and ashort suture section 54.Long suture section 52 is then attached toshort suture section 54 by passingneedle 50 andlong suture section 52 throughshort suture section 54 at a region 56 (FIG. 2B). Pullinglong suture section 52 away from fixation member 16 (FIG. 2C) then drawsregion 56 towardfixation member 16 forming a knot 60 (FIG. 2D).Suture 10 is now secured tofixation member 16. - Referring to FIGS.2E-2I,
suture 10 is now attached tofixation member 18 by passinglong suture section 52 throughholes 18 a, 18 b in second fixation member 18 (FIG. 2E).Long suture section 52 now defines a first suture length 62 andsecond suture length 64.Slip knot 28 is formed by passingfixation member 16 undersuture length 64, oversuture length 64, and under suture length 62, forming a loop 66 (FIG. 2F); then passingfixation member 16 oversuture lengths 62 and 64, forming a loop 68 (FIG. 2G); and then passingfixation member 16 undersuture lengths 64 and 62 (FIG. 2G), and finally through loop 68 (FIG. 2H). Pullingfixation member 16 relative tofixation member 18 tightens slip knot 28 (FIG. 2I). Pullingfree end 30 ofsuture 10 now acts to slidesuture 10 throughslip knot 28, whileslip knot 28 limits sliding ofsuture 10 in the opposite direction whensuture 10 is under tension. - Referring to FIG. 3, a
delivery device 99 for implantingdevice 8 intissue 14 includes asheath 200 and aneedle 100.Sheath 200 is preferably formed from plastic, andneedle 100 is preferably metal.Needle 100 has an open distal end 111 with a pointed,tissue piercing tip 108.Needle 100 has aninner surface 102 defining alumen 104 and aslot 110 both extending to open distal end 111.Slot 110 extends from anouter surface 106 ofneedle 100 tolumen 102. As described further below,needle 100 receivesfixation member lumen 104 and slot 110 withsuture 10 tied tofixation members Sheath 200 defines a lumen 202 which receivesneedle 100 anddevice 8 withsuture 10 positioned betweenneedle 100 andsheath 200 and extending through ahole 201 defined at a proximal end 203 ofsheath 200.Sheath 200 has a distal end 202 from which needle 100 extends. - Referring also to FIGS.4-4B,
slot 110 has a proximal,closed end 120 and a distalopen end 140.Fixation members 16 and 18 (which are generally described in U.S. Ser. No. 09/453,120, supra) have the same shape with each fixation member including acylindrical region 151 received withinlumen 104 ofneedle 100, and afin 152 extending throughslot 110 with aportion 154 offin 152 extending beyondouter surface 106 ofneedle 100.Fixation member 16 is located at adistal region 112 ofslot 110, andfixation member 18 is located at aproximal region 114 ofslot 110. Distal end 111 ofneedle 100 is indented, for example, crimped at 150, andinner surface 102 ofneedle 100 has a protrusion extending intolumen 104, for example, adimple 130, neardistal end 140.Dimple 130 and crimp 150 are sized to resist unintentional passage of the fixation members either overdimple 130 or through open distal end 111, though only a small force on the fixation members is needed to overcome the resisting load applied to the fixation members by crimp 150 anddimple 130.Fixation members surfaces 152 a which aid in passage through tissue, and aflat surface 154 a which aid in retention of the fixation member at their deployment sites. - During manufacturing, to position
fixation members needle 100, aftersuture 10 is attached tofixation members fixation member 18 is loaded inneedle 100 by passingfixation member 18 through distal end 111 and slidingfixation member 18 alonglumen 104 and slot 110 toproximal end 120 ofslot 110.Fixation member 16 is then loaded inneedle 100 by passingfixation member 16 through distal end 111 andpositioning fixation member 16 inregion 112.Dimple 130 and crimp 150 are then formed.Fixation member 16 is now restrained from unintentional movement in the proximal direction bydimple 130 and in the distal direction by crimp 150. Alternatively, as shown in FIG. 4C, rather thandimple 130, a needle 100 a includes a ramp 130 a formed by making three slits in awall 101 of needle 100 a and bending a section of the wall toward the inside of the needle. - Referring also to FIG. 5,
needle 100 has aproximal end 160 mounted to ahandle 180. Located withinneedle 100, proximal offixation member 18, is a push rod 170 (FIG. 4) used to advancefixation member 18, as described below. Handle 180 includes anactuating slider 190 attached to pushrod 170 for advancingpush rod 170. Oncedevice 8 is secured toneedle 100, as described above,sheath 200 is placed overneedle 100, with the majority ofsuture 10 located within and protected bysheath 200.Sheath 200 also covers the majority offixation member 18 and helps keepfixation member 18 in position.Sheath 200 is then secured to handle 180 by an interference fit. Thedistance needle 100 extends fromsheath 200 determines the penetration depth ofneedle 100 into the tissue.Delivery device 99 is supplied to the surgeon withdevice 8 pre-loaded inneedle 100. - Referring to FIG. 5A, an outer
protective tube 200 a can be placed oversheath 200.Tube 200 a protects the needle tip during shipping. If it is desired to supply the surgeon with a variable length depth stop,tube 200 a can be provided withgradations 201. The surgeon scorestube 200 a to provide the tube with the desired length for the surgical procedure.Tube 200 a is coupled to handle 190 by a loose interference fit to allow the surgeon to removetube 200 a iftube 200 a is not being used during surgery. - Referring to FIG. 5B, to eliminate the need for placement of
delivery device 99 through an arthroscopy cannula, a removable cannula 202 a, formed, for example, of a plastic material, can be placed oversheath 200. Cannula 202 a has a distal, tissue penetrating tip 203 a and aslot 204 a extending from a proximal end 205 a of cannula 202 a to within about 0.02 inches of distal tip 203 a to define a distal region 206 a. Slot 204 a permits the removal of cannula 202 a fromdelivery device 99 after placement of the delivery device in the joint. To remove cannula 202 a, the surgeon grasps the cannula and moves it laterally relative tosheath 200, untilsheath 200 slides throughslot 204 a. The surgeon then pulls cannula 202 a proximally, which breaks cannula region 206 a, permitting complete removal of cannula 202 a. - Referring to FIGS.6-11, in use, preferably under arthroscopic guidance, the user inserts
delivery device 99 into, for example, the knee joint, and passesneedle 100 throughsoft tissue 14 and acrosstear 12, untilneedle tip 108 andfixation member 16 extend throughtissue surface 20.Dimple 130 preventsfixation member 16 from sliding proximally in response to forces acting onfixation member 16 during insertion throughtissue 14.Fixation member 16 is now positioned with flat,tissue facing surface 154 a ofportion 154 offin 152 extending beyondneedle surface 106 engaging tissue surface 20 (FIG. 7). The user then pullsdelivery device 99 proximally removingneedle 100 from tissue 14 (FIG. 8). The force of the engagement offixation member 16 withtissue surface 20 during removal ofneedle 100 overcomes the retention force of crimp 150.Fixation member 16 slides distally out of open end 111 ofneedle 100 and remains atsurface 20. During the retraction ofneedle 100, a portion ofsuture 110 withknot 28 is played out ofdelivery device 99, withsuture 10 extending throughsoft tissue 14 acrosstear 12. - The user then advances
slider 190, advancingrod 170 to pushfixation member 18 distally, overdimple 130, to reside inregion 112 betweendimple 130 and crimp 150 (FIG. 9). The user then movesneedle 100 to a spaced location to the side ofexit point 229 ofsuture 10 fromtissue 14, andre-inserts needle 100 intosoft tissue 14, acrosstear 12, and throughsurface 20, untilneedle tip 108 andfixation member 18 extend through tissue surface 20 (FIG. 10). The user then pullsdelivery device 99 proximally removingneedle 100 from tissue 14 (FIG. 11). The force of the engagement offixation member 18 withtissue surface 20 during removal ofneedle 100 overcomes the retention force of crimp 150 such thatfixation member 18 slides distally out of open end 111 ofneedle 100 and remains atsurface 20, as described above with reference tofixation member 16. -
Free end 30 ofsuture 10 extends fromsheath 200, as shown in FIG. 11. The user graspsfree end 30 ofsuture 10 with forceps or by hand and pulls onfree end 30 ofsuture 10. This shortens the length of suture betweenfixation members 16 and 18 (suture portions 10 a-10 c), bringingsides tear 12 into juxtaposition, as shown in FIG. 11. Whenfree end 30 ofsuture 10 is pulled,slip knot 28 moves closer tofixation member 18. Depending on the length of suture betweenfixation members slip knot 28 will either be ontissue surface 26 or move withintissue 14.Slip knot 28 allowssuture 10 to slide in the direction ofarrow 32, but does not allowsuture 10 to slide in the opposite direction. The tension placed onsuture 10 by pulling on the suture relative tofixation members long sides 255 are in contact withtissue surface 20.Excess suture 10 can then be cut off. Further manipulation ofsuture 10 is not needed to securefixation members - Referring to FIG. 12, rather than a
slip knot 28 acting as a retainingelement allowing suture 10 to be tightened while resisting loosening ofsuture 10, here, aseparate retaining element 210 is positioned onfree end 30 ofsuture 10. While pulling onfree end 30, the surgeon advances retainingelement 210 throughtissue 14, in the direction of arrow 212, until retainingelement 210 is positioned againstfixation member 18, as shown in dashed line. This action acts to closetear 12 andsecure device 8 in place. - Retaining
element 210 defines a through bore 216 for receivingsuture 10. The material of retainingelement 210, e.g., acetal, is selected, and the diameter of through bore 216 is sized relative to suture 10 to provide the desired amount of friction betweensuture 10 and retainingelement 210 for adequate securement. Thus, the user can slidesuture 10 in the direction of arrow 212, but adequate friction is provided betweensuture 10 and retainingelement 210 to limit sliding of retainingelement 210 in the opposite direction under normal loads in the knee joint. - Referring to FIG. 12A, a retaining element210 a defines two
angled channels free end 30 ofsuture 10. Retaining element 210 a has a generally cylindrical surface 221 and ends 222, 223.Channel 218 has afirst opening 224 atend 222 andsecond opening 225 on surface 221.Channel 220 has afirst opening 226 atend 223 and asecond opening 227 on the same side of surface 221 aschannel 218.Suture 10 follows a tortuous path throughchannel 218, over surface 221 betweenopenings channel 220 withfree end 30 extending from opening 226. The tortuous path aids in securement ofdevice 8. - In FIG. 12B, rather the channel opening on surface221 being on the same side, a retaining element 210 b defines two angled channels 218 a, 220 a each having a
channel end Suture 10 thus wraps part way around element 210 b to aid in securement ofdevice 8. - Referring to FIG. 12C, rather than positioning the retaining element on
suture 10 aftersuture 10 exits fromfixation member 18, here retainingelement 210, 210 a, or 210 b is positioned alongsuture 10 between the portions ofsuture 10 passing throughfixation member 18. - Retaining
elements 210, 210 a, 210 b are slidably received onsuture 10. In the embodiments of FIGS. 12-12B, the retaining element slides oversuture 10, changing position relative tofixation member 18, while in the embodiment of FIG. 12C,suture 10 slides within the retaining element with the position of the retaining element being relatively unchanged relative tofixation member 18. - Referring to FIG. 13,
device 8 can be secured totissue 14 using a simpleoverhand knot 230.Knot 230 is first tied infree end 30 ofsuture 10 and pushed, in the direction ofarrow 240, throughtissue 14 and againstfixation member 18, as shown in dashed line. Referring to FIGS. 13A and 13B,knot 230 includes three crossing points, labeled, 230 a, 230 b, and 230 c. When under tension, T,knot 230 tends to tighten upon itself, rather than slide in the direction ofarrow 240 making it difficult to advanceknot 230 alongsuture 10. To enable tension, T, to be applied to suture 10 at thesame time knot 230 is advanced in the direction ofarrow 240, a knot pusher 250 is used. Knot pusher 250 is configured to keep suture at crossingpoints 230 a, 230 b, and 230 c from touching, such thatknot 230 does not tighten upon itself under tension, T. This permitsknot 230 to slide along the tensioned suture when knot pusher 250 is advanced in the direction ofarrow 240. - Knot pusher250 has a cylindrical body 252 and an end post 254. Body 252 defines a first groove 254 and a
second groove 256 on one surface, and athird groove 258 that is an extension ofgroove 256 on an opposite surface.Grooves 254 and 256 form and X pattern, andgrooves loop 260 extending around body 252. The three grooves differ in depth, withgroove 256 being the shallowest and groove 258 being the deepest. Thus, whensuture 10 is formed into an overhand knot and positioned withingrooves points 230 a, 230 b, and 230 c does not touch. Onceknot 230 is advanced againstfixation member 18, knot pusher 250 is removed by pulling retrograde on the knot pusher. To aid in removal of knot pusher 250, a tube (not shown) can be advanced over knot pusher 250 between the knot pusher and the suture. As the tube is advanced pastsuture crossing point 230 a, the suture is stripped from knot pusher 250. - Referring to FIG. 14, one or more
additional fixation members 18 a with aslip knot 28 formed insuture 10 can be added todevice 8. In use,fixation members suture 10 being tightened to securefixation members Additional fixation member 18 a is then implanted andsuture 10 tightened to securefixation member 18 a in place. To accommodate additional fixation members,slot 110 inneedle 100 ofdelivery device 99 is extended. To permit access tofixation member 18 bypush rod 170,additional fixation members 18 a preferably include a through bore (not shown) for passage therethrough bypush rod 170. Pushrod 170 preferably is biased off angle such that whenpush rod 170 is pulled out of the passage infixation member 18 a, the push rod is no longer aligned with the passage. Subsequent advancement ofpush rod 170 then engages an end face offixation member 18 a to push the fixation member toward the tip of theneedle 100, rather than back through the passage.Slider 190 is preferably spring loaded such that afterfixation member 18 is pushed out ofneedle 100,push rod 170 springs back to engage thenext fixation member 18 a. - Referring to FIG. 14A, the positions of
fixation member needle 100 can be swapped, withfixation member 18 located indistal region 112 such thatfixation member 18 is implanted in the tissue prior to implantation offixation member 16. Referring to FIG. 14B, rather than suture 10 being fixed tofixation member 16, here suture 10 is attached tofixation member 16 the same as the attachment tofixation member 18, such that asecond slip knot 28 a is formed and a secondfree end 30 a of suture extends fromfixation member 16. To securefixation members suture 10 are pulled. - Referring to FIG. 15, in an application for securing soft tissue262 to
bone 264, asuture 266 is attached to fixation members in the form of a first anchor member 270 and a second anchor member 272. Members 270, 272 are, for example, TAG WEDGE bone anchors available from Smith & Nephew, Inc. Endoscopy Division, Andover, Mass. Other bone anchors known in the art can be employed.Suture 266 has a first end 274 fixed to anchor member 270, a second free end 276, and a slip knot 268, formed as described above forslip knot 28. Suture 266 preferably passes through aseparate suture loop 278, rather than through 272 itself.Suture loop 278 acts as a goodpulley allowing suture 266 to slide relative tosuture loop 278. - In use, the user forms bone holes280, 282 in
bone 264. The user then implants anchor member 270 in bone hole 280, withsuture 266 already threaded as shown, followed by implanting anchor member 272 in bone hole 282. The user then pulls on free end 276 ofsuture 266, which brings soft tissue 262 againstbone 264. Slip knot 268 limits loosening ofsuture 266. By usingsuture loop 278,suture 266 is not located within bone hole 282 in use thus limiting the possibility of trappingsuture 266 againstwall 284 of bone hole 282. Ifsuture 266 were trapped in bone hole 282, pulling free end 276 ofsuture 266 would not result in shortening the length of suture between anchors 270, 272, which acts to secure soft tissue 262 againstbone 264. - Referring to FIGS.16A-16C, a
wound closure device 1010 includes afirst suture anchor 1012, asecond suture anchor 1014, and a flexible member, e.g.,suture 1016 that connectsanchor 1012 toanchor 1014. The suture is tied to the first anchor with a conventional knot, but movably attached to the second anchor, allowing a surgeon to shorten the length of suture between the anchors, and thereby close a wound.First anchor 1012 has a generally solidcylindrical body 1018 extending axially from a distal surface 1019 a to a flat proximal surface 1019 b. To facilitate passage offirst anchor 1012 into tissue, both anupper portion 1022 a and a lower portion 1022 b of surface 1019 a are beveled relative to the axis ofcylindrical body 1018, forming a roundeddistal tip 1022 c.Upper portion 1022 a is beveled at an angle a relative to the axis ofcylindrical body 1018, and lower portion 1022 b is beveled at an angle β relative to the axis. - Attached to
cylindrical body 1018 is a fin-shapedprojection 1020 that extends fromupper portion 1022 a of distal surface 1019 a to proximal surface 1019 b.Fin 1020 defines two horizontally transverse holes, 1024 a and 1024 b.Suture 1016 is attached tofirst anchor 1012 by passing the suture throughhole 1024 a in a first direction (e.g., out of the page in FIG. 16A), through hole 1024 b in a second direction (e.g., into the page in FIG. 16A), and then forming aconventional knot 1025 nearfin 1020.Conventional knot 1025 rigidly fixessuture 1016 to the first anchor. -
Second anchor 1014 has a distal surface 1029 a, a proximal surface 1029 b, and a generallycylindrical body 1028 extending axially from surface 1029 a to surface 1029 b. Attached tobody 1028 is anappendage 1026.Appendage 1026 is generally L-shaped in cross-section, and extends along an axial length ofbody 1028, from surface 1029 a to surface 1029 b. - Distal surface1029 a of
anchor 1014 is beveled in a manner similar to anchor 1012: anupper portion 1031 a of surface 1029 a forms an angle θ relative to an axis ofbody 1028, and a lower portion 1031 b of surface 1029 a forms an angle φ relative to the body's axis, forming a rounded distal tip 1031 c. Proximal surface 1029 b ofanchor 1014 is flat. - The L-shape of
appendage 1026 is formed by two perpendicular sections: astem 1036 attached tocylindrical body 1028 along an axial length of the body, and abase 1032 attached to the stem.Base 1032 defines a verticallytransverse hole 1030, and stem 1036 defines two horizontallytransverse holes 1034 a and 1034 b.Holes 1034 a and 1034 b are perpendicular tohole 1030, but all three holes pass throughanchor 1014 in a direction generally parallel to sides 1029 a and 1029 b. - Each of the three
holes anchor 1014 to an interior, partially enclosed, protectedregion 1039.Region 1039 is defined bybase 1032, aninterior surface 1037 ofstem 1036, and aconcave groove 1035 withincylindrical body 1028.Groove 1035 extends axially acrossbody 1028, along the line whereinterior surface 1037 connects tobody 1028. -
Suture 1016 is movably attached tosecond anchor 1014 with a one-way knot 1040. One-way knot 1040 includes a first portion ofsuture 1016 that forms aloop 1042, and a second portion of suture that passes aroundbody 1028 and through the loop.Loop 1042 is formed within theprotective region 1039 defined bygroove 1035,surface 1037, andbase 1032.Region 1039 acts to separateloop 1042 from tissue whendevice 1010 is implanted within tissue, preventing the tissue from interfering with the sliding action of one-way knot 1040. - To form one-
way knot 1040,suture 1016 is first passed from an exterior ofanchor 1014, throughhole 1034 a intoregion 1039, and then back out hole 1034 b to the exterior, formingloop 1042 withinregion 1039. The suture is then passed over the rounded, exterior surface 1041 ofcylindrical body 1028, back intoregion 1039, throughloop 1042, and then to the exterior throughhole 1030.Suture 1016 terminates at afree end 1044. - One-
way knot 1040 allows the length of suture betweenfirst anchor 1012 andsecond anchor 1014 to be shortened, but not lengthened. A surgeon can shorten the length of suture between the anchors by pulling onfree end 1044, which draws additional suture in the direction of the arrows in FIG. 16A, throughholes anchors first anchor 1012 away from second anchor 1014 (i.e., pullingsuture 1016 in the opposite direction of the arrows), thenloop 1042 squeezesportion 1046 ofsuture 1016 against aninterior compression surface 1043 ofstem 1036, preventing further lengthening of the distance between the anchors. - If
suture 1016 is a braided suture, as opposed to a smooth suture, then suture 1016 should be threaded throughsecond anchor 1014 in a particular direction. Referring to FIG. 16D, a braided suture 1016 a is formed from numerous threads 1017 a braided from left to right in FIG. 16D. Braided suture 1016 a slides more easily if it is pulled in the direction of braiding (i.e., in the direction of arrow S in FIG. 16D) than if it is pulled against the braiding (in the direction of arrow L). Thus, ifsuture 1016 is a braided suture, then suture 1016 should be threaded throughsecond anchor 1014 in the direction of braiding. If threaded in the direction of braiding, the suture will slide more easily in the direction of the arrows in FIG. 16A, and less easily in the direction opposing the arrows. - The cylindrical portions of
anchors device 1010. For example,cylindrical body 1018 has a diameter D1 of about 0.04 inches, andcylindrical body 1028 has a diameter D2 approximately equal to diameter D1. Fin-shapedprojection 1020 and L-shapedappendage 1026, however, are configured to protrude through a longitudinal slit in the needle. Delivery ofdevice 1010 using a hollow needle is described below, with reference to FIGS. 20A-20D and 21A-21D. -
First anchor 1012 has an overall axial length L1 of, e.g., about 0.19 inches, andfin 1020 has a height H1 of, e.g., about 0.03 inches.Second anchor 1014 has an overall axial length L2 of, e.g., about 0.22 inches, a width W2 of, e.g., about 0.06 inches, and a height H2 of, e.g., about 0.07 inches. Angle α is, e.g., about 30 degrees, angle β is, e.g., about 40 degrees, angle θ is, e.g., about 30 degrees, and angle φ is, e.g., about 40 degrees. -
Anchors Anchors - FIG. 17 illustrates the use of
wound closure device 1010 to repair a tornmeniscus 1050.Meniscus 1050 is a C-shaped, rubbery, shock-absorbing structure located between the tibia and femur inside the knee.Meniscus 1050 has atear 1052 that unnaturally separates distalmeniscal tissue 1054 fromproximal tissue 1056. A width WM ofmeniscus 1050, as measured frompoints 1060 a and 1060 b to anexterior surface 1058 of the meniscus is, e.g., about 0.25 inches. - When
device 1010 is implanted withinmeniscus 1050, bothanchors abut surface 1058, separated by a distance of, e.g., about 1 cm.Suture 1016 passes fromfirst anchor 1012, intodistal tissue 1054, acrosstear 1052, and emerges fromproximal tissue 1056 atpoint 1060 a.Suture 1016 then passes again intoproximal tissue 1056 at point 1060 b, again traversestear 1052, and emerges outsurface 1058, where it attaches tosecond anchor 1014 via one-way knot 1040. Fromsecond anchor 1040,suture 1016 passes again intodistal tissue 1054, traversestear 1052, and emerges fromproximal tissue 1056 at or near point 1060 b.Free end 1044 ofsuture 1016 emerges fromproximal tissue 1056. - Referring to FIGS. 17, 18A, and18B, once
device 1010 is implanted, a surgeon can closetear 1052 by pulling onfree end 1044 ofsuture 1016. When the surgeon pulls onfree end 1044, four separate movements occur in succession. First, friction betweensuture 1016 andbody 1028 rotatessecond anchor 1014 until alower surface 1033 ofbase 1032 is flush againstmeniscal surface 1058, as shown in FIG. 18A. Second, tension insuture 1016 pulls the center offin 1020 towardssurface 1058, causingfirst anchor 1012 to align againstsurface 1058 transversely to the portion ofsuture 1016 that exitsanchor 1012, with bothfin 1020 and the axial length ofbody 1018 pressing againstmeniscal surface 1058. Third, continued pulling onfree end 1044 draws additional suture throughholes knot 1040, in the direction of the arrows of FIG. 16A, lengtheningfree end 1044 and shortening the length of suture betweenanchors anchors suture 1016 between the anchors, which pullsdistal tissue 1054 andproximal tissue 1056 together, closingtear 1052. Sinceloop 1042 remains withinprotected region 1039 as the surgeon pulls onfree end 1044,base 1032 separatesloop 1042 from tissue, andsuture 1016 does not become wedged between tissue andanchor 1014 when the surgeon pulls on the suture's free end. Oncetear 1052 has been closed, one-way knot 1040 prevents the two anchors from pulling apart, and prevents the tear from re-opening. - The final successive movement occurs when the surgeon releases
free end 1044, after closingtear 1052. When the surgeon releases the free end, the tension insuture 1016 between the two anchors pullsbody 1028 ofanchor 1014 away fromfree end 1044, causingsecond anchor 1014 to rotate in the direction of arrow R (FIG. 18B), untilbody 1028 abutsmeniscal surface 1058, trapping aportion 1062 ofsuture 1016 betweenbody 1028 andsurface 1058. (For clarity,suture 1016 is shown spaced slightly frombody 1028 and stem 1036 in FIG. 18B. In actuality,suture 1016 is flush against the surfaces ofanchor 1014 aftersuture 1016 is tensioned by the surgeon.) - When
second anchor 1014 is in its final position, shown in FIG. 18B,suture 1016 is locked in place. The length of suture betweenanchors loop 1042 of one-way knot 1040 pressesportion 1046 of the suture againstsurface 1043 ofstem 1036. In addition, the length of suture between the anchors resists being further shortened, sinceportion 1062 ofsuture 1016 is wedged betweenbody 1028 andsurface 1058 of the meniscus. -
Wound closure device 1010 is preferably deployed withinmeniscus 1050 arthroscopically, using ahollow needle 1070. Referring to FIG. 19,hollow needle 1070 defines abore 1072 and an opendistal tip 1074. The diameter DB ofbore 1072 is slightly larger than diameter D1 ofbody 1018 offirst anchor 1012, and diameter D2 ofbody 1028 ofsecond anchor 1014, allowingbody 1018 andbody 1028 to fit slidably within the bore.Needle 1070 also includes alongitudinal slit 1076 through a wall of the needle.Slit 1076 extends proximally fromopen tip 1074, and communicates withbore 1072.Slit 1076 is sized and shaped to allowfin 1020 offirst anchor 1012 and L-shapedappendage 1026 ofsecond anchor 1014 to protrude fromneedle 1070. -
Needle 1070 also includes aplunger 1080.Plunger 1080 entersbore 1072 through aproximal opening 1082 inneedle 1070, and extends to proximal surface 1019 b offirst anchor 1012.Plunger 1080 passes bysecond anchor 1014 by sliding alonggroove 1035. Whenplunger 1080 is positioned as shown in FIG. 19, slidingplunger 1080 in the direction of arrow A pushesfirst anchor 1012 distally, but does not movesecond anchor 1014. - Prior to surgery,
suture 1016 is attached toanchors anchors bore 1072 ofneedle 1070.Second anchor 1014 is loaded first, by insertingcylindrical head 1028 intobore 1072, throughopen tip 1074, such thatappendage 1026 protrudes throughslit 1076.Second anchor 1014 is pushed proximally intoslit 1076, untilstem 1036 abuts aproximal surface 1077 of the slit. Next,first anchor 1012 is loaded into the distal most position inneedle 1070 by insertingcylindrical body 1018 throughtip 1074, intobore 1072, such thatfin 1020 protrudes throughslit 1076. Bothanchors distal tip 1074. - After the anchors have been loaded,
plunger 1080 is inserted intobore 1072 throughproximal opening 1082.Plunger 1080 is slid pastsecond anchor 1014 alonggroove 1035, until atip 1084 of the plunger abuts proximal surface 1019 b offirst anchor 1012. - Attachment of
suture 1016 toanchors needle 1070 can be performed at the time of manufacture, i.e., pre-loaded, or immediately prior to surgery. - During surgery (or prior to surgery), the surgeon first pushes
plunger 1080 in the direction of arrow A toseparate anchors bore 1072. The surgeon pushes the plunger until the anchors are separated by at least a distance L, as shown in FIG. 19, where L is greater than width WM ofmeniscus 1050. Distance L is, e.g., about 0.35 inches. - Referring to FIGS. 17 and 20A-20D (not to scale), the surgeon next pushes needle 1070 through
meniscus 1050, in the direction of arrow A, untilfin 1020 offirst anchor 1012 passes entirely throughexterior surface 1058 of the meniscus. As the surgeon pushesneedle 1070 through the tissue, he or she holdsplunger 1080 steady, to preventanchor 1012 from sliding in the direction of arrow B as the needle is pushed through the meniscal tissue. Since the separation distance L is greater than the width WM ofmeniscus 1050,second anchor 1014 does not enter the meniscus at this point in the procedure. - The surgeon next forces first anchor1012 out of
needle 1070 throughtip 1074 by pushingplunger 1080 in the direction of arrow A, and then seats anchor 1012 againstsurface 1058 of the meniscus by pulling onfree end 1044 ofsuture 1016. Onceanchor 1012 has been seated,needle 1070 is pulled in the direction of arrow B, back throughmeniscus 1050, acrosstear 1052, and out the hole atpoint 1060 a (FIG. 20B). - The surgeon then reinserts
needle 1070 intomeniscus 1050 at point 1060 b, and again passes the needle through the meniscus in the direction of arrow A, acrosstear 1052, untiltip 1074 passes throughsurface 1058. To ejectsecond anchor 1014, the surgeon withdrawsplunger 1080 in the direction of arrow B untiltip 1084 of the plunger is proximal to surface 1029 b ofanchor 1014. The surgeon then maneuvers plunger 1080 untiltip 1084 contacts surface 1029 b, and then pushes the plunger in the direction of arrow A, forcingsecond anchor 1014 throughtip 1074.Plunger 1080 andneedle 1070 are then fully withdrawn in the direction of arrow B, leaving bothanchors surface 1058, as shown in FIG. 20D. The surgeon can thentension suture 1016, positioning the anchors againstsurface 1058 andclosing tear 1052, by pulling onfree end 1044, as described above with reference to FIG. 17. - Alternative deployment methods are possible. For example,
device 1010 can be extracted fromneedle 1070 by engagingfin 1020 withsurface 1058, rather than by using aplunger 1080. Referring to FIG. 21A-21D (not to scale), in this embodiment,plunger 1080 is not passed throughgroove 1035 tofirst anchor 1012. Instead,tip 1084 ofplunger 1080 always remains proximal toanchor 1014. - When the two anchors are loaded into
bore 1072 ofneedle 1070, aspacer 1086 is placed between the anchors.Spacer 1086 is a simple cylindrical bar, preferably made from a material that degrades quickly in the body, such as salt.Spacer 1086 has a longitudinal length LS greater than width WM ofmeniscus 1050. Length LS is, e.g., about 0.35 inches. - During surgery, the surgeon first pushes
needle 1070 throughmeniscus 1050, in the direction of arrow A, untilfin 1020 passes entirely throughexterior surface 1058 of the meniscus (FIG. 21A). As the surgeon pushesneedle 1070 through the tissue,surface 1077 ofslit 1076 engagesstem 1036 ofanchor 1014, preventing the two anchors and the spacer from sliding in the direction of arrow B withinbore 1072. (In addition, the surgeon can holdplunger 1080 steady to prevent the two anchors from sliding in the direction of arrow B.) - The surgeon next pulls the needle in the direction of arrow B, back through
meniscus 1050, acrosstear 1052, and out the hole atpoint 1060 a (FIG. 21B). As the surgeon withdraws the needle,fin 1020 engagessurface 1058, andfirst anchor 1012 is pulled out ofneedle 1070, throughtip 1074. As before, the surgeon then seatsanchor 1012 againstsurface 1058 by pulling onfree end 1044 ofsuture 1016. Sincespacer 1086 is larger than width WM ofmeniscus 1050, the spacer preventssecond anchor 1014 from enteringmeniscus 1050, and therefore preventssecond anchor 1014 from also being pulled out ofneedle 1070 asneedle 1070 is pulled in the direction of arrow B. - Next, the surgeon reinserts
needle 1070 intomeniscus 1050 at point 1060 b, and again passes the needle through the meniscus in the direction of arrow A, acrosstear 1052, untiltip 1074 passes throughsurface 1058. The surgeon then pushesplunger 1080 in the direction of arrow A, ejecting bothspacer 1086 andsecond anchor 1014 out ofneedle 1070 through tip 1074 (FIG. 21C). The needle is then fully withdrawn frommeniscus 1050, in the direction of arrow B, leaving bothanchors surface 1058, as shown in FIG. 21D. The surgeon then pulls onfree end 1044 to position the anchors and close the tear, as described above.Spacer 1086 can either be removed by the surgeon, or left within the body to degrade. - In another alternative deployment method, a modified wound closure device is deployed in
meniscus 1050 in reverse, second anchor first. Referring to FIG. 22A, a modified wound closure device includes afirst anchor 1112 that has a beveled face 1119 a, but lacks a fin.Anchor 1112 has an axial, generallycylindrical body 1118 that defines twotransverse holes 1124 a and 1124 b.Suture 1016 is attached to anchor 1112 by threading the suture throughhole 1124 a in a first direction, through hole 1124 b in a second direction, and then tying aconventional knot 1125. - Referring to FIGS.22B-22E (not to scale), in this reverse deployment embodiment,
second anchor 1014 is positioned distally inbore 1072, withfirst anchor 1112 directly proximal.Tip 1084 ofplunger 1080 resides immediately proximal tofirst anchor 1112 inbore 1072. In operation, the surgeon first pushesneedle 1070 throughmeniscus 1050, in the direction of arrow A, untiltip 1074 passes throughsurface 1058. The surgeon then pushesplunger 1080 in the direction of arrow A far enough to forcesecond anchor 1014 throughtip 1074, but not far enough to ejectfirst anchor 1112. - After
anchor 1014 has been ejected, the surgeon pulls the needle in the direction of arrow B, back throughmeniscus 1050, acrosstear 1052, and outpoint 1060 a (FIG. 22C). Sincefirst anchor 1112 does not include a fin, it does not protrude throughslit 1076, and does not engage tissue when the needle is pulled in the direction of arrow B. Next, the surgeon reinsertsneedle 1070 into the meniscus at point 1060 b, and again passes the needle throughmeniscus 1050 in the direction of arrow A, acrosstear 1052, untiltip 1074 passes throughsurface 1058. The surgeon then ejectsfirst anchor 1112 by pushingplunger 1080 in the direction of arrow A, (FIG. 22D), and withdrawsneedle 1070 frommeniscus 1050. The surgeon then positions the anchors and closes tear 1052 by pulling on free end 1044 (FIG. 22E), as described above. - Alternative configurations of
second anchor 1014 and one-way knot 1040 are possible. - For example, referring first to FIGS. 23A and 23B,
suture 1016 can be threaded throughsecond anchor 1014 so that the loop is located against anexterior surface 1637 ofstem 1036, rather than withinregion 1039. In this embodiment,suture 1016 is threaded throughsecond anchor 1014 by first passing the suture aroundbase 1032, intoregion 1039, and then out ofregion 1039 throughhole 1034 a. The suture then passes back intoregion 1039 through hole 1034 b, forming aloop 1642adjacent surface 1637. After forming the loop, the suture passes throughhole 1030 to the exterior, and then throughloop 1642, terminating atfree end 1644. - When the surgeon pulls
free end 1644 ofsuture 1016, the anchor rotates untilsurface 1637 facessurface 1058 of meniscus 1050 (FIGS. 17 and 18A-18B).Cylindrical body 1028 causes part ofsurface 1637 to remain elevated abovesurface 1058, creating asmall gap 1639 that containsloop 1642.Loop 1642, therefore, does not become wedged between tissue andsurface 1637 when the surgeon pullsfree end 1644 to tension the suture. - Referring to FIG. 24,
second anchor 1214 has a structure similar toanchor 1014, except thatanchor 1214 lacks abase 1032.Anchor 1214 includes acylindrical body 1228 and astem 1236 that define a wedge-shaped, partiallyenclosed region 1239 therebetween.Stem 1236 defines two holes, 1234 a and 1230, andbody 1228 defines one transverse hole 1234 b.Holes 1234 a and 1230 are generally parallel, and are both generally perpendicular to hole 1234 b. Asuture 1216 passes from a first anchor (not shown) through hole 1234 a intoregion 1239, and then through hole 1234 b to the exterior of the anchor, forming a loop 1242 withinregion 1239. The suture then wraps aroundbody 1228 back intoregion 1239, through loop 1242, and out ofregion 1239 throughhole 1230, terminating atfree end 1244. Alternatively,suture 1216 can wrap aroundbody 1228 two or more times before passing back intoregion 1239. - As in the previous embodiments, pulling on
free end 1244 tensions suture 1216 and shortens the length of suture between the anchors. Pulling onsuture 1216 in an opposite direction, however, causes loop 1242 to press a portion 1246 of the suture against a compression surface 1243. Since loop 1242 is located within protectedregion 1239, and is therefore spaced from the meniscal surface, loop 1242 does not become wedged between tissue and the anchor when the surgeon tensions suture 1216. Unlike the previous embodiments, however,anchor 1214 does not rotate after the surgeon tensions the suture and releasesfree end 1244. - Referring to FIG. 25,
second anchor 1314 includes a generallycylindrical body 1328 and an offset, generally rectangular appendage 1326. Appendage 1326 andbody 1328 define a partially protectedregion 1339. As withanchor 1014, a front surface 1329 a ofanchor 1314 is beveled. - Appendage1326 defines three holes, 1330, 1334 a, and 1334 b.
Holes 1334 a and 1330 are generally straight, while hole 1334 b defines an arc through an inside of appendage 1326. Asuture 1316 passes from a first anchor (not shown) through straight hole 1334 a intoregion 1339.Suture 1316 then passes out ofregion 1339 through arc-shaped hole 1334 b, forming aloop 1342 withinregion 1339. The suture then wraps around acorner 1320 of body 1326, passes throughloop 1342, and throughhole 1330, terminating at free end 1344. As with the embodiments of FIGS. 16, 22A-22B, and 23, pulling on free end 1344 shortens the length of suture between the anchors, but pulling onsuture 1316 in an opposite direction causesloop 1342 to squeeze a portion 1346 of the suture against acompression surface 1343 of appendage 1326, preventing further movement. Like the embodiment of FIG. 23,anchor 1314 does not rotate after the suture is tensioned and released. - Referring to FIG. 26,
second anchor 1414 includes a generallycylindrical body 1428 extending from a beveled distal surface 1429 a to a flat proximal surface 1429 b. A generallyrectangular appendage 1426 also extends from surface 1429 a to surface 1429 b.Rectangular appendage 1426 is attached tobody 1428 along the long side of the rectangle, and is centered along an axial length ofbody 1428.Body 1428 andappendage 1426 define a protected region 1439. -
Appendage 1426 defines two holes, 1434 a and 1430, andbody 1428 defines two transverse holes, 1434 b and 1434 c. Hole 1434 b is located entirely withinbody 1428, but hole 1434 c is located at ajuncture 1492 betweenbody 1428 andappendage 1426.Holes - A
suture 1416 extends from a first anchor (not shown), throughhole 1434 a into region 1439, and then out of region 1439 through hole 1434 b, forming aloop 1442 within region 1439. The suture then passes back into region 1439 through hole 1434 c, throughloop 1442, and out of region 1439 throughhole 1430, terminating at free end 1444. - As with the other described second anchor embodiments, pulling on free end1444 tensions suture 1416 and shortens the length of suture between the anchors, but pulling on
suture 1416 in an opposite direction causesloop 1442 to squeeze aportion 1446 of the suture against a compression surface 1443 ofappendage 1426, preventing further movement. Region 1439 is separated from the meniscal tissue bybody 1428, preventingloop 1442 from wedging betweenanchor 1414 and tissue when the surgeon pulls on free end 1444.Anchor 1414 does not rotate after the surgeon tensions and releases the suture. - Referring to FIG. 27, second anchor1514 includes a generally
cylindrical body 1528 and anappendage 1526. Bothbody 1528 andappendage 1526 extend from a beveled distal surface 1529 a to a flat proximal surface 1529 b.Appendage 1526 includes a stem 1536 attached tobody 1528, and ahead 1532 attached to stem 1536. Stem 1536 is rectangular in cross-section andhead 1532 is D-shaped in cross-section, giving appendage 1526 a mushroom-shaped cross-section. Stem 1536,head 1532, andbody 1528 define a partially enclosed, protectedregion 1539. - Stem1536 defines two
transverse holes 1534 a and 1534 b, andbody 1528 defines a single transverse hole 1530 located at a juncture 1592 betweenbody 1528 and stem 1536. Asuture 1516 passes from a first anchor (not shown), throughhole 1534 a into protectedregion 1539, and then out ofregion 1539 through hole 1534 b, forming aloop 1542 withinregion 1539.Suture 1516 then passes around D-shapedhead 1532 through atransverse groove 1594 inhead 1532, back intoregion 1539, throughloop 1542, and out hole 1530, terminating at free end 1544. As with the other described embodiments of the second anchor, pulling on free end 1544 shortens the distance between the two anchors, but pulling onsuture 1516 in an opposite direction causesloop 1542 to squeeze a portion 1546 of the suture against a compression surface 1543 of stem 1536, preventing further movement. Thatloop 1542 is located withinregion 1539 prevents the loop from becoming wedged between the anchor and tissue when the surgeon pulls on free end 1544. Anchor 1514, likeanchors - Referring to FIGS.28A-28D and FIGS. 29-31, the second anchor can have a T shape or a crescent shape, and can be deployed at a surface of the meniscus or inter-body. Referring to FIGS. 28A and 28B,
second anchor 1730 has a T-shape. Thebase 1732 of the T defines three through-holes, 1734 a, 1734 b, and 1734 c, and thestem 1736 of the T is configured to penetrate meniscal tissue.Stem 1736 is offset from base 1732 so that the stem does not block hole 1734 b. Referring to FIGS. 28C and 28D,second anchor 1814 has a flat, generally circularproximal surface 1836, and a roundeddistal surface 1838, giving the anchor a generally hemispherical or “crescent” shape. (Alternatively,surface 1836 can be concave.)Anchor 1814 defines three through-holes, 1830, 1834 a, and 1834 b. The holes pass in an axial direction from the anchor's proximalcircular surface 1836 to its distalrounded surface 1838. - FIG. 29 illustrates deployment of a
device 1810 that has a crescent-shapedsecond anchor 1814, and a “pulley”anchor 1813.Pulley anchor 1813 does not act as a dead-end for a suture, nor does it include a one-way knot. Instead,pulley anchor 1813 includes two through-holes, 1824 a and 1824 b. Asuture 1816 passes through hole 1824 a in a first direction, and then through hole 1824 b in a second direction, such thatsuture 1816 can slide overpulley anchor 1813 in either direction.Pulley anchor 1813 can have the shape and structure of anchor 1012 (i.e., the holes are located on a fin), the simple cylindrical structure ofanchor 1112 of FIG. 22A, or numerous other structures. - In operation, anchors1813 and 1814 are deployed using, e.g., a
hollow needle 1070, such thatanchor 1814 is positioned on a proximal side ofmeniscus 1050, andanchor 1813 is deployed againstdistal surface 1058. When deployed,suture 1816 passes through hole 1834 a of crescent-shapedanchor 1814 in a generally proximal direction (arrow P), from roundedsurface 1838 tocircular surface 1836, and then through hole 1834 b in a generally distal direction (arrow D), forming aloop 1842. Fromloop 1842, the suture passes through meniscal tissue, through hole 1824 a ofpulley anchor 1813, through hole 1824 b ofanchor 1813, and back through meniscal tissue to the crescent shaped anchor. The suture then passes throughloop 1842, terminating atfree end 1844. The opposite end 1845 ofsuture 1816 includes a knob or aknot 1847 that prevents end 1845 from passing through hole 1834 a. Thus,suture 1816 begins atanchor 1814, in addition to forming the one-way knot atanchor 1814. - Referring to FIG. 30, rather than beginning at
anchor 1814, the suture can be affixed to afirst anchor 1012. In FIG. 30, adevice 1811 includes afirst anchor 1012 and crescent-shapedsecond anchor 1814.Suture 1816 passes throughholes 1024 a and 1024 b ofanchor 1012, forming aknot 1025 as shown in FIG. 16A. Fromknot 1025,suture 1816 passes through meniscal tissue and then through holes 1834 a and 1834 b ofanchor 1814, formingloop 1842. Fromloop 1842, the suture passes back through meniscal tissue tofirst anchor 1012, and then through a fixedloop 1843 located betweenknot 1025 andfirst anchor 1012. The suture then passes back through meniscal tissue, throughhole 1830 ofanchor 1814, and throughloop 1842, terminating atfree end 1844. - When a surgeon pulls on
free end 1844 indevice 1811, the mechanical advantage is 3:1, sincesuture 1816 passes between the two anchors three times. By comparison, indevice 1810, the mechanical advantage is 2:1. - Referring to FIG. 31, the crescent shaped
anchor 1814 ofdevice 1810 can be deployed inter-body (i.e., embedded within meniscal tissue), rather than against a surface of the meniscus. In this deployment method,device 1810 is deployed in the manner described above with reference to FIG. 29, or using another deployment method. After positioning the anchors and tensioningfree end 1844, however, the surgeon pushesanchor 1814 into the meniscal tissue, using, e.g., a needle. To facilitate pushinganchor 1814 into the tissue, apoint 1817 ofanchor 1814 can be sharp. - Other types of second anchors described herein, whether or not they include a sharp point, can also be positioned inter-body.
- In each of the described embodiments of the second anchor, the one-way knot can be left “loose” until after both the first and second anchors are positioned against the meniscus. In such an embodiment, the suture would be very long, e.g., more than 12 cm long, such that the one-way knot includes considerable slack, and the loop portion of the knot is accessible to the surgeon's fingers. In this embodiment, the surgeon can position the first and second anchors against
backside 1058 by pulling on both the free end and the loop itself. Once the anchors are satisfactorily positioned, the surgeon tightens the knot by pulling on the free end. - The second anchor can employ one-way tightening schemes other than a “one-way knot.” For example, referring to FIG. 32, a
device 1650 includesfirst anchor 1012, a second anchor 1652, and twosutures holes 1656 and 1658. When anchors 1012 and 1652 are positioned againstbackside 1058 ofmeniscus 1050,suture 1616 passes fromfirst anchor 1012, throughholes 1060 a and 1060 b in the meniscus, and then throughholes 1656 and 1658 of anchor 1652, terminating atfree end 1660.Suture 1616 does not form a one-way knot at second anchor 1652. Instead,suture 1616 simply passes throughholes 1656 and 1658 in succession, such that anchor 1652 acts as a pulley anchor. - The second suture,
suture 1654, passes only through hole 1656 of anchor 1652, and through hole 1060 b of the meniscus. A portion 1662 ofsuture 1654, distal to hole 1656, is thicker than the remainder ofsuture 1654. This thicker portion 1662 cannot pass through hole 1656. (The thickness of portion 1662 is exaggerated in FIG. 32.) - In operation, a surgeon deploys the two anchors as described above with respect to other embodiments, and then pulls on
free end 1660 ofsuture 1616 to position the anchors againstbackside 1058 and close the tear in the meniscus. Oncesuture 1616 is tensioned to the surgeon's satisfaction, the surgeon pulls onsuture 1654 in the proximal direction (arrow P), until a segment of portion 1662 wedges into hole 1656. Portion 1662 wedges suture 1616 in place within hole 1656, preventing the length ofsuture 1616 between the two anchors from increasing, and thereby locking the two anchors in place. - Modifications of other portions of
wound closure device 1010 are also possible. For example, the fin-shapedprojection 1020 of the first anchor need not have the shape shown in the figures. Other types of projections capable of protruding through a needle opening and engaging tissue can be used. In addition, as described above with reference to FIGS. 21A, the first anchor need not include any projection, but can instead be a simple cylinder defining holes for affixation of the suture. - Instead of attaching the suture to the first anchor using a
conventional knot 1025, the suture can be welded or glued to the anchor, or can be spliced. - Referring to FIG. 33A, the first anchor need not include an extended, cylindrical body, but can instead have a button-shaped body. Button-shaped first anchor1712 includes a circular distal side 1719 a and a circular proximal side 1719 b. Two
axial holes 1724 a and 1724 b pass from side 1719 a to side 1719 b. Asuture 1716 is attached to anchor 1712 by passing throughhole 1724 a in a first direction, through hole 1724 b in a second direction, and then forming aconventional knot 1725 on the distal side of the anchor. - Referring to FIG. 33B, button-shaped first anchor1712 is deployed against a
proximal surface 1796 ofmeniscus 1050, andsecond anchor 1014 is deployed againstsurface 1058.Suture 1716 passes from first anchor 1712 intoproximal tissue 1056 at point 1760, such thatknot 1725 is located within the tissue. From point 1760,suture 1716 passes acrosstear 1052 tosecond anchor 1014, then throughsecond anchor 1014 in the manner described above with reference to FIG. 16. Fromsecond anchor 1014, the suture passes back intodistal tissue 1054, acrosstear 1052, and emerges fromproximal tissue 1056 at point 1760. The suture then terminates atfree end 1744. As with the embodiments described above, pulling onfree end 1744 tensions the suture and closes the tear. - Alternatively, button-shaped anchor1712 can be deployed on the distal side of the tear adjacent
second anchor 1014, using the methods described above with reference to FIGS. 17, 20A-20D, 21A-21D, and 22A-22D. - The second anchor need not include a
groove 1035 to allow passage of a plunger. Instead, the second anchor can define an axial through-hole for passage of the plunger. - Rather than a suture, the first and second anchors can be connected with other types of flexible members.
- The wound closure device can include more than two suture anchors. For example, in addition to the first and second anchors, the device can include a third anchor identical in structure and function to the second anchor. In operation, after deploying the second anchor against
surface 1058 ofmeniscus 1050, the surgeon could again pass the suture acrosstear 1052, adding an additional stitch, and then deploy the third anchor againstsurface 1058. After deploying all three anchors, the surgeon would pull on the free end of the suture, causing the suture to slide over both the second and third anchors, shortening the length of suture between the third and first anchors, and thereby closing the wound. - When more than two anchors are used, one or more of the anchors can be a pulley, such as
pulley anchor 1813 described above with reference to FIG. 29. For example, the device could include afirst anchor 1012, apulley anchor 1813, and asecond anchor 1014. The suture would be affixed to the first anchor, would slide over the pulley anchor, and form a one-way knot at the second anchor. - Depending on the size of the tissue wound, more than three anchors can be used. The additional anchors can all be pulley anchors, can all be similar to the second anchor, or can be both additional pulleys and additional second anchors.
- The wound closure devices need not be deployed using a needle, and need not be deployed arthroscopically. Instead, a surgeon can place the anchors against the tissue during an open procedure.
- The wound closure devices can be used to repair tissue wounds other than meniscal tears. For example, the devices can be used to repair tears in skin, muscles, and ligaments, and to re-attach tissue to support structures, such as bones.
- Referring to FIGS.34-36, a
device 308 for repairing atear 12 intissue 14 includes asuture 310 attached to asingle fixation member 326.Fixation member 326 defines throughholes suture 310.Suture 310 has afirst end 312 attached to suture 310 at point 314 (as described above with reference to FIG. 2B) to form a loopedend 316 remote fromfixation member 326, and a second,free end 334. - When implanted in the knee joint,
fixation member 326 lies on asurface 20 oftissue 14. Loopedend 316 is located intear 12 and extends alongsurface 26 oftissue 14.Suture 310 extends throughtissue 14, passing through loopedend 316 intear 12, and emerging attissue surface 20 wheresuture 310 loops throughfixation member 326.Suture 310 extends back throughtissue 14, passing through loopedend 316 intear 12 and through aslip knot 321 formed insuture 310, and emerging attissue surface 26. As described further below, afterdevice 308 is positioned intissue 14, the user pulls onfree end 334 ofsuture 310, in the direction ofarrow 520, to bringsides tear 12 together into juxtaposition (as shown in FIG. 34).Slip knot 321 limits loosening ofsuture 310. Alternatively, loopedend 316 is located onsurface 20 betweenfixation member 326 andsurface 20, as shown in dashed line in FIG. 34. - Referring to FIGS.37-37B, a
delivery device 399 for implantingdevice 308 includes asuture holder 400 andneedle 460.Suture holder 400 includes atube 410 defining alumen 415 through which needle 460 extends, ashaft 420, and adistal portion 430.Distal portion 430 has afirst tine 440defining grooves second tine 450defining grooves Needle 460 has abeveled tip 461 and aslot 462 in atop portion 463 ofneedle 460. - When assembled,
fastening member 326 with attachedsuture 310 is positioned inslot 462 withsuture 310 preformed with loopedend 316 andslip knot 321.Slip knot 321 is formed as described above with reference to FIGS. 2A-2I, though wherefixation member 16 is positioned in FIGS. 2A-2I,suture 310 is formed as looped end 316 (FIG. 37C). Loopedend 316 is positioned onsuture holder 400 withingrooves tines 440, 450 (FIG. 37B), and extends along abottom side 480 ofshaft 420. As shown in FIG. 37,delivery device 399 includes ahandle 451 with apush knob 453 for advancingneedle 460 relative to sutureholder 400. - Referring to FIG. 38, in use, the user inserts
distal portion 430 ofsuture holder 400 intotear 12 oftissue 14, and then advancesneedle 460 throughtissue 14, traversingtear 12, and exitingtissue 14 attissue surface 20.Needle 460 passes betweentines end 316 of suture 310 (FIG. 39). The user then retractsneedle 460 from tissue 14 (FIG. 40). The contact offastening member 326 withtissue surface 20 during the retraction ofneedle 460 acts to pushfastening member 326 out ofneedle 460 such thatfastening member 326 remains atsurface 20, as described above with reference to FIG. 7. Pulling onfree end 334 ofsuture 310 bringssides tear 12 into juxtaposition.Slip knot 321 securesdevice 308 in place.Excess suture 310 can then be cut off. - Referring to FIG. 41, rather than securing
device 308 with a slip knot,suture 310 includes a retaining element in the form of a Chinese trap or hand cuff 495, that is, an element that when pulled on, tightens around something disposed within the element.Free end 334 ofsuture 310 is slidably received within trap 495. Whenfree end 334 ofsuture 310 is pulled in the direction ofarrow 520 trap 495 is stretched, eventually gripping suture passing therethrough to securesuture 310 anddevice 308. The retaining element can also take the form of retaining elements described above with reference to FIGS. 12-12C and 13. - Referring to FIG. 42, a device799 for repairing
tear 12 intissue 14 includes abarbed fastening member 800 and asuture 820.Suture 820 has anend 810 attached to fasteningmember 800.Suture 820 is formed inloop 830 with asecond end 832 ofsuture 820 attached tosuture 820.Delivery device 399 can be used to deploy device 799 withsuture 820 being tightened to closetear 12 by pushingfastening member 800 in the direction ofarrow 840, rather than pulling on a free end of suture.Barbed fastening member 800 limits loosening ofsuture 820. - Referring to FIG. 43, an alternative embodiment of a
fixation member 600 includes throughbores 610, 620 withradiused comers 615 to reduce friction between suture 470 andfixation member 600. Referring to FIG. 44, another embodiment of a fixation member 650, which can be used in any of the above embodiments, includes asolid rod 660 withends braided suture 670 attached to ends 680, 690. Suture 670 forms aloop 700 for receivingsuture 10 orsuture 310.Loop 700 lines up withsuture - The fixation members, securement elements, and suture of the above embodiments can be formed of a biodegradable material.
- Other embodiments are within the scope of the following claims.
Claims (83)
1. A wound closure device comprising:
a first anchor;
a second anchor; and
a flexible member connecting the first anchor to the second anchor, the flexible member being movably attached to the second anchor, such that pulling on a free end of the flexible member shortens a length of the flexible member between the first and second anchors.
2. The device of claim 1 , wherein the movable attachment of the flexible member to the second anchor enables the length of the flexible member between the first and second anchors to be shortened, but not lengthened.
3. The device of claim 2 , wherein the movable attachment includes a knot formed in the flexible member at the second anchor.
4. The device of claim 3 , wherein the knot includes a first portion of the flexible member that forms a loop, and a second portion that passes over a surface of the second anchor and through the loop.
5. The device of claim 4 , wherein the surface comprises an exterior surface of the second anchor.
6. The device of claim 4 , wherein the knot is configured such that pulling on the free end causes the flexible member to slide through the loop to shorten the length of the flexible member between the first and second anchors, but pulling on the flexible member in an opposite direction in order to increase the length of the flexible member between the first and second anchors causes the loop to press the second portion against a compression surface of the second anchor, resisting increase in the length of the flexible member between the first and second anchors.
7. The device of claim 4 , wherein the second portion includes the free end.
8. The device of claim 4 , wherein the second anchor defines a partially enclosed region, and the loop is formed within the partially enclosed region.
9. The device of claim 8 , wherein the second anchor includes a first section that defines a plurality of holes, and the first portion of the flexible member passes through the plurality of holes to form the loop.
10. The device of claim 8 , wherein the second anchor includes a second section that defines a passage that connects to the partially enclosed region, and the free end of the suture passes through the passage.
11. The device of claim 1 , wherein the second anchor further comprises a rounded body and an appendage attached to the rounded body, the rounded body and the appendage defining a partially enclosed region therebetween, wherein at least a portion of the flexible member passes through the partially enclosed region.
12. The device of claim 11 , wherein the flexible member wraps around the rounded body.
13. The device of claim 11 , wherein the rounded body has a generally cylindrical shape, and is sized and shaped to fit within the bore of a hollow needle.
14. The device of claim 13 , wherein the rounded body defines an axial groove, the groove extending across an axial length of the rounded body.
15. The device of claim 11 , wherein the appendage has a cross-sectional shape selected from the group consisting of a rectangle, an L, and a D.
16. The device of claim 11 , wherein the flexible member is movably attached to the second anchor to form a knot, the knot allowing the length of the flexible member between the first and second anchors to be shortened, but not lengthened, and the knot including the portion of the flexible member that passes through the partially enclosed region.
17. The device of claim 1 , wherein the second anchor has a generally hemispherical shape or a generally crescent shape.
18. The device of claim 17 , wherein the second anchor has a sharp tip configured to penetrate tissue.
19. The device of claim 1 , wherein the second anchor is generally T-shaped.
20. The device of claim 1 , wherein the second anchor defines a through-hole, and the flexible member passes through the through-hole.
21. The device of claim 20 , further comprising a second flexible member that passes through the through-hole, the second flexible member having a thickened portion that has a width greater than a width of the through-hole, such that the thickened portion cannot pass through the through-hole.
22. The device of claim 1 , wherein the first anchor comprises a generally cylindrical body, the body being sized and shaped to fit within a bore of a hollow needle.
23. The device of claim 22 , wherein the first anchor further comprises a projection extending from the cylindrical body.
24. The device of claim 23 , wherein the projection comprises a longitudinal fin.
25. The device of claim 23 , wherein the projection defines a hole for passage of the flexible member therethrough.
26. The device of claim 1 , wherein the first anchor has a button shape, and defines a hole for passage of a suture therethrough.
27. The device of claim 1 , wherein the flexible member is fixed to the first anchor.
28. The device of claim 1 , wherein the flexible member comprises a suture.
29. The device of claim 1 , further comprising a retaining element coupled to the flexible member, the retaining element being slidably received by the flexible member and acting to limit loosening of the flexible member relative to the second fixation member.
30. The device of claim 1 , further comprising a retaining element coupled to the flexible member, the retaining element being movable relative to the second fixation member and acting to limit loosening of the flexible member relative to the second fixation member.
31. A wound closure kit comprising:
a needle having an open tip and defining a longitudinal bore that connects to the open tip;
first and second anchors disposed within the needle bore; and
a flexible member connecting the first anchor to the second anchor.
32. The kit of claim 31 , wherein the needle defines a longitudinal slit that connects to the bore and to the open tip.
33. The kit of claim 32 , wherein the first anchor includes a projection that protrudes through the slit.
34. The kit of 32, wherein the second anchor includes an appendage that protrudes through the slit, and the flexible member is attached to the appendage.
35. The kit of claim 32 , wherein the flexible member is fixed to the first anchor, and movably attached to the second anchor.
36. The kit of claim 31 , wherein the flexible member comprises a suture.
37. A method of closing a tissue wound comprising:
providing a wound closure device having a first anchor, a second anchor, and a flexible member movably attached to the second anchor;
positioning the first anchor against tissue;
passing the flexible member across the wound;
positioning the second anchor against tissue; and
pulling on a free end of the flexible member to shorten a length of the flexible member between the first and second anchors, thereby closing the wound.
38. The method of claim 37 , wherein the flexible member is slidably attached to the second anchor by a one-way knot, such that after completion of the pulling step, the length of the flexible member between the first and second anchors remains shortened.
39. The method of claim 37 , wherein the first positioning step includes positioning the first anchor on a first side of the wound, the passing step includes passing the flexible member from the first side to a second side of the wound, engaging tissue on the second side, and returning the flexible member to the first side, and the second positioning step includes positioning the second anchor on the first side of the wound.
40. The method of claim 37 , wherein the providing step includes providing a needle having an open tip and defining a bore that connects to the open tip, the first and second anchors being at least partially disposed within the bore.
41. The method of claim 40 , wherein the needle further defines a slit that connects to the bore and to the open tip, the first anchor includes a projection that protrudes through the slit, and the first positioning step includes engaging the projection with tissue to remove the first anchor from the bore.
42. The method of claim 38 , wherein the providing step includes providing a second anchor that defines a partially enclosed region, the partially enclosed region housing at least a portion of the one-way knot, and the partially enclosed region being located such that during the pulling step, the portion of the one-way knot disposed within the partially enclosed region avoids contact with tissue.
43. The method of claim 37 , wherein the providing step includes providing a device in which the flexible member passes through a through-hole in the second anchor, and the device further includes a second flexible member that also passes through the through-hole, the second flexible member having a thickened portion that is wider than the through hole, and the method further comprises:
pulling the second flexible member until the thickened portion wedges into the through hole.
44. A method of repairing a tear in a meniscus comprising:
providing a tear closing device having a first anchor, a second anchor, and a flexible member movably attached to the second anchor;
positioning the first anchor against the meniscus;
passing the flexible member across the tear;
positioning the second anchor against the meniscus; and
pulling on a free end of the flexible member to shorten a length of the flexible member between the first and second anchors, thereby closing the tear.
45. The method of claim 44 , wherein the providing step includes providing a tear closing device in which the flexible member is fixed to the first anchor.
46. The method of claim 44 , wherein the first positioning step includes positioning the first anchor against an external surface of the meniscus, on a first side of the tear, the passing step includes passing the flexible member from the first side to a second side of the tear, engaging tissue on the second side, and returning the flexible member to the first side, and the second positioning step includes positioning the second anchor against the external surface.
47. The method of claim 44 , wherein the first and second anchors are positioned against external surfaces of the meniscus on opposite sides of the tear.
48. A surgical method, comprising:
positioning a fixation member relative to tissue,
moving a flexible member coupled to the fixation member relative to the fixation member to bring two tissue surfaces together, and
moving a retaining element coupled to the flexible member relative to the fixation member, the retaining element acting to limit loosening of the flexible member relative to the fixation member.
49. The surgical method of claim 48 wherein the step of moving the flexible member comprises pulling the flexible member.
50. The surgical method of claim 48 wherein the step of moving the flexible member also accomplishes the step of moving the retaining element.
51. The surgical method of claim 50 further comprising providing the retaining element in the form of a slip knot.
52. The surgical method of claim 48 wherein the step of moving the retaining element includes moving the retaining element relative to the flexible element.
53. The surgical method of claim 52 further comprising providing the retaining element in the form of a friction element which permits sliding of the retaining element relative to the flexible element in only one direction.
54. The surgical method of claim 48 further comprising providing the retaining element in the form of an overhand knot.
55. The surgical method of claim 54 further comprising advancing the overhand knot along the flexible element.
56. The surgical method of claim 48 further comprising providing the retaining element in the form of a Chinese trap.
57. The surgical method of claim 48 wherein the step of moving the flexible member includes pulling on only one end of the flexible member.
58. The surgical method of claim 48 further comprising positioning a second fixation member relative to the tissue, the second fixation member being coupled to the flexible member.
59. The surgical method of claim 58 wherein the second fixation member is movably coupled to the flexible member, the step of moving the flexible member including pulling on two ends of the flexible member.
60. The surgical method of claim 58 wherein the second fixation member is fixedly attached to the flexible member, the step of moving the flexible member including pulling on only one end of the flexible member.
61. The surgical method of claim 48 wherein the step of positioning the fixation member includes positioning the fixation member on an outer surface of the tissue.
62. The surgical method of claim 61 wherein the two tissue surfaces are both soft tissue.
63. The surgical method of claim 48 wherein the step of positioning the fixation member includes positioning the fixation member in a bone hole.
64. The surgical method of claim 48 wherein a first of the two tissue surfaces is bone, and a second of the two tissue surfaces is soft tissue.
65. The surgical method of claim 48 wherein the step of positioning the fixation member includes passing the fixation member through a loop of the flexible member.
66. The surgical method of claim 65 further comprising positioning the loop within a tear in soft tissue.
67. A method for repairing a tear in soft tissue, comprising:
advancing a fixation member coupled to a flexible member through tissue on either side of the tear and through a loop of the flexible member, and
tensioning the flexible member to bring two tissue surfaces on either side of the tear together.
68. The method of claim 67 further comprising positioning the loop within the tear.
69. The method of claim 67 further comprising pulling an end of the flexible member to bring the two tissue surfaces together.
70. The method of claim 67 further comprising providing the fixation member in the form of a barbed member.
71. An apparatus for repairing a tear in soft tissue, comprising:
at least two fixation members,
a flexible member substantially immovably secured to a first of the fixation members and movably coupled to a second of the fixation members, and
a retaining element coupled to the flexible member, the retaining element being movable relative to the second fixation member and acting to limit loosening of the flexible member relative to the second fixation member.
72. An apparatus for repairing a tear in soft tissue, comprising:
at least two fixation members,
a flexible member substantially immovably secured to a first of the fixation members and movably coupled to a second of the fixation members, and
a retaining element coupled to the flexible member, the retaining element being slidably received by the flexible member and acting to limit loosening of the flexible member relative to the second fixation member.
73. An apparatus for repairing a tear in soft tissue, comprising:
a fixation member, and
a flexible member movably coupled to the fixation member, a first end of the flexible member being looped back and secured to the flexible member for forming a loop, the loop being remote from the fixation member.
74. A flexible member holder, comprising:
a shaft,
a first tine at an end region of the shaft defining a first region for receiving a first portion of a loop of a flexible member, and
a second tine at the end region of the shaft defining a second region for receiving a second portion of the loop of the flexible member.
75. The holder of claim 74 wherein the shaft comprises a tube.
76. The holder of claim 74 wherein each of the first and second regions comprises a groove.
77. A device for repairing a tear in a tissue, comprising:
a needle having a distal region and a proximal region, the distal region being defined between two holding elements,
a first fixation member positioned within the distal region and a second fixation member positioned within the proximal region, and
a flexible member coupled to the first and second fixation members.
78. The device of claim 77 wherein one of the holding elements comprises a crimp in the needle in the distal region.
79. The device of claim 77 wherein one of the holding elements comprises a dimple extending into a lumen of the needle.
80. The device of claim 77 wherein one of the holding elements comprises a ramp extending into a lumen of the needle.
81. The device of claim 77 wherein the needle defines a slot through a wall of the needle, the first and second fixation members extending through the slot.
82. The device of claim 77 further comprising a protector tube, the tube defining a bore, wherein the needle is sized to fit into an end of the protector tube.
83. The device of claim 77 further comprising a push pin, the pin being sized to fit inside the needle.
Priority Applications (10)
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US09/886,367 US20020019649A1 (en) | 1999-12-02 | 2001-06-22 | Closure device and method for tissue repair |
US10/278,474 US7887551B2 (en) | 1999-12-02 | 2002-10-23 | Soft tissue attachment and repair |
US10/918,445 US7651509B2 (en) | 1999-12-02 | 2004-08-16 | Methods and devices for tissue repair |
US12/684,722 US9833231B2 (en) | 1999-12-02 | 2010-01-08 | Apparatus for tissue repair |
US12/684,752 US9220494B2 (en) | 1999-12-02 | 2010-01-08 | Methods for tissue repair |
US13/242,499 US8366744B2 (en) | 1999-12-02 | 2011-09-23 | Apparatus for tissue repair |
US13/757,440 US9545251B2 (en) | 1999-12-02 | 2013-02-01 | Apparatus for tissue repair |
US14/537,794 US9295461B2 (en) | 1999-12-02 | 2014-11-10 | Methods for tissue repair |
US15/583,397 US10433833B2 (en) | 1999-12-02 | 2017-05-01 | Apparatus for tissue repair |
US16/251,605 US10376260B2 (en) | 1999-12-02 | 2019-01-18 | Apparatus for tissue repair |
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US09/704,926 US7153312B1 (en) | 1999-12-02 | 2000-11-02 | Closure device and method for tissue repair |
US09/886,367 US20020019649A1 (en) | 1999-12-02 | 2001-06-22 | Closure device and method for tissue repair |
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US11/025,837 Expired - Fee Related US8512375B2 (en) | 1999-12-02 | 2004-12-30 | Closure device and method for tissue repair |
US13/944,682 Expired - Fee Related US8834524B2 (en) | 1999-12-02 | 2013-07-17 | Closure device and method for tissue repair |
US14/454,243 Expired - Fee Related US9492160B2 (en) | 1999-12-02 | 2014-08-07 | Closure device and method for tissue repair |
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US13/944,682 Expired - Fee Related US8834524B2 (en) | 1999-12-02 | 2013-07-17 | Closure device and method for tissue repair |
US14/454,243 Expired - Fee Related US9492160B2 (en) | 1999-12-02 | 2014-08-07 | Closure device and method for tissue repair |
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Cited By (427)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20030021827A1 (en) * | 2001-07-16 | 2003-01-30 | Prasanna Malaviya | Hybrid biologic/synthetic porous extracellular matrix scaffolds |
US20030049299A1 (en) * | 2001-07-16 | 2003-03-13 | Prasanna Malaviya | Porous delivery scaffold and method |
US20030078617A1 (en) * | 2001-07-16 | 2003-04-24 | Schwartz Herbert E. | Unitary surgical device and method |
US20030083739A1 (en) * | 2001-09-24 | 2003-05-01 | Robert Cafferata | Rational drug therapy device and methods |
US20030130694A1 (en) * | 1999-12-02 | 2003-07-10 | Ray Bojarski | Soft tissue attachment and repair |
US20040010287A1 (en) * | 1999-08-09 | 2004-01-15 | Bonutti Peter M. | Method and apparatus for securing tissue |
KR20040006162A (en) * | 2002-07-11 | 2004-01-24 | 이은정 | Method for suture using button |
US20040116949A1 (en) * | 2002-12-11 | 2004-06-17 | Ewers Richard C. | Apparatus and methods for forming gastrointestinal tissue approximations |
US20040138683A1 (en) * | 2003-01-09 | 2004-07-15 | Walter Shelton | Suture arrow device and method of using |
US20040143344A1 (en) * | 2001-07-16 | 2004-07-22 | Prasanna Malaviya | Implantable tissue repair device and method |
US20040146296A1 (en) * | 2002-06-06 | 2004-07-29 | Irwin Gerszberg | Integrated electrical/optical hybrid communication system with revertive hitless switch |
US20040147958A1 (en) * | 2002-12-11 | 2004-07-29 | Usgi Medical | Apparatus and methods for forming and securing gastrointestinal tissue folds |
US20040153074A1 (en) * | 2003-02-05 | 2004-08-05 | Bojarski Raymond A. | Tissue anchor and insertion tool |
US20040166169A1 (en) * | 2002-07-15 | 2004-08-26 | Prasanna Malaviya | Porous extracellular matrix scaffold and method |
US20040225305A1 (en) * | 1999-06-25 | 2004-11-11 | Usgi Medical | Apparatus and methods for forming and securing gastrointestinal tissue folds |
US20050065397A1 (en) * | 2003-01-15 | 2005-03-24 | Usgi Medical Inc. | Endoluminal tool deployment system |
US20050090139A1 (en) * | 2002-03-28 | 2005-04-28 | Rowland White | Contact |
US20050187577A1 (en) * | 2004-02-24 | 2005-08-25 | David Selvitelli | Methods and devices for repairing tissue |
US20050203500A1 (en) * | 2004-03-09 | 2005-09-15 | Usgi Medical Inc. | Apparatus and methods for mapping out endoluminal gastrointestinal surgery |
US20050203488A1 (en) * | 2004-03-09 | 2005-09-15 | Usgi Medical Inc. | Apparatus and methods for mapping out endoluminal gastrointestinal surgery |
US20050251210A1 (en) * | 2004-05-07 | 2005-11-10 | Usgi Medical Inc. | Methods and apparatus for grasping and cinching tissue anchors |
US20050251209A1 (en) * | 2004-05-07 | 2005-11-10 | Usgi Medical Inc. | Apparatus and methods for positioning and securing anchors |
US20050251176A1 (en) * | 2004-05-07 | 2005-11-10 | Usgi Medical Inc. | System for treating gastroesophageal reflux disease |
US20050249772A1 (en) * | 2004-05-04 | 2005-11-10 | Prasanna Malaviya | Hybrid biologic-synthetic bioabsorbable scaffolds |
US20050251161A1 (en) * | 2004-05-07 | 2005-11-10 | Usgi Medical Inc. | Needle assembly for tissue manipulation |
US20050250984A1 (en) * | 2004-05-07 | 2005-11-10 | Usgi Medical Inc. | Multiple removable apparatus and methods for manipulating and securing tissue |
US20050249771A1 (en) * | 2004-05-04 | 2005-11-10 | Prasanna Malaviya | Hybrid biologic-synthetic bioabsorbable scaffolds |
US20050251162A1 (en) * | 2004-05-07 | 2005-11-10 | Usgi Medical Inc. | Apparatus and methods for manipulating and securing tissue |
US20050251208A1 (en) * | 2004-05-07 | 2005-11-10 | Usgi Medical Inc. | Linear anchors for anchoring to tissue |
US20050251157A1 (en) * | 2004-05-07 | 2005-11-10 | Usgi Medical Inc. | Apparatus and methods for positioning and securing anchors |
US20050251165A1 (en) * | 2004-05-07 | 2005-11-10 | Usgi Medical Inc. | Tissue manipulation and securement system |
US6972027B2 (en) | 2002-06-26 | 2005-12-06 | Stryker Endoscopy | Soft tissue repair system |
US20050277981A1 (en) * | 2004-06-09 | 2005-12-15 | Usgi Medical Inc. | Apparatus and methods for optimizing anchoring force |
US20050277983A1 (en) * | 2004-06-09 | 2005-12-15 | Usgi Medical Inc. | System for optimizing anchoring force |
US20050277966A1 (en) * | 2004-06-09 | 2005-12-15 | Usgi Medical Inc. | Compressible tissue anchor assemblies |
US20050283192A1 (en) * | 1999-12-02 | 2005-12-22 | Torrie Paul A | Closure device and method for tissue repair |
US20060020276A1 (en) * | 2004-07-23 | 2006-01-26 | Usgi Medical Inc. | Apparatus and methods for achieving prolonged maintenance of gastrointestinal tissue folds |
US20060084994A1 (en) * | 2000-04-04 | 2006-04-20 | Anulex Technologies, Inc. | Devices and methods for the treatment of spinal disorders |
US20060089646A1 (en) * | 2004-10-26 | 2006-04-27 | Bonutti Peter M | Devices and methods for stabilizing tissue and implants |
US20060122608A1 (en) * | 2004-12-08 | 2006-06-08 | Fallin T W | System and method for anchoring suture to bone |
US20060128296A1 (en) * | 2004-10-29 | 2006-06-15 | Schwan Wade E | Intestine processing device and associated method |
US20060135638A1 (en) * | 2004-12-22 | 2006-06-22 | Pedrozo Hugo A | Method for organizing the assembly of collagen fibers and compositions formed therefrom |
US20060135971A1 (en) * | 2004-05-07 | 2006-06-22 | Usgi Medical Inc. | System for treating gastroesophageal reflux disease |
US20060178680A1 (en) * | 2005-02-07 | 2006-08-10 | Regen Biologics, Inc. | System and method for all-inside suture fixation for implant attachment and soft tissue repair |
US20060189993A1 (en) * | 2004-11-09 | 2006-08-24 | Arthrotek, Inc. | Soft tissue conduit device |
US20060200198A1 (en) * | 2004-08-31 | 2006-09-07 | Riskin Daniel J | Systems and methods for closing a tissue opening |
US20060217762A1 (en) * | 2004-06-09 | 2006-09-28 | Usgi Medical, Inc. | Compressible tissue anchor assemblies |
US20060247642A1 (en) * | 2004-11-09 | 2006-11-02 | Stone Kevin T | Tissue fixation device |
US20060271074A1 (en) * | 2005-05-26 | 2006-11-30 | Ewers Richard C | Methods and apparatus for securing and deploying tissue anchors |
US20060271073A1 (en) * | 2005-05-26 | 2006-11-30 | Usgi Medical Inc. | Methods and apparatus for securing and deploying tissue anchors |
US20060293709A1 (en) * | 2005-06-24 | 2006-12-28 | Bojarski Raymond A | Tissue repair device |
US20070010857A1 (en) * | 2005-07-05 | 2007-01-11 | Mitralign, Inc. | Tissue anchor, anchoring system and methods of using the same |
EP1750591A1 (en) * | 2004-05-07 | 2007-02-14 | USGI Medical Inc | Apparatus and methods for positioning and securing anchors |
US20070043255A1 (en) * | 2005-08-22 | 2007-02-22 | O'donnell Pat D | Surgical instrument for treating female pelvic prolapse |
US20070083236A1 (en) * | 2005-06-24 | 2007-04-12 | Smith & Nephew, Inc. | Methods and devices for tissue repair |
US20070129811A1 (en) * | 2000-08-04 | 2007-06-07 | Plouhar Pamela L | Reinforced small intestinal submucosa |
US20070167950A1 (en) * | 2005-12-22 | 2007-07-19 | Tauro Joseph C | System and method for attaching soft tissue to bone |
US20070175488A1 (en) * | 2006-01-27 | 2007-08-02 | Usgi Medical Inc. | Methods and apparatus for revision of obesity procedures |
US20070185532A1 (en) * | 2006-02-03 | 2007-08-09 | Arthrotek, Inc. | Soft tissue repair assembly and associated method |
US20070219558A1 (en) * | 2006-03-15 | 2007-09-20 | Allen Deutsch | Method and apparatus for arthroscopic surgery using suture anchors |
US20070225736A1 (en) * | 2006-03-23 | 2007-09-27 | Ethicon Endo-Surgery, Inc. | Suture Tensioning Device |
US20070233257A1 (en) * | 2000-04-04 | 2007-10-04 | Anulex Technologies, Inc. | Devices and Methods for Annular Repair of Intervertebral Discs |
US20070288023A1 (en) * | 2006-06-12 | 2007-12-13 | Greg Pellegrino | Soft tissue repair using tissue augments and bone anchors |
US20080065120A1 (en) * | 2005-10-31 | 2008-03-13 | Zannis Anthony D | Surgical instrument, kit and method for creating mattress-type stitches |
US20080082128A1 (en) * | 2006-09-29 | 2008-04-03 | Arthrotek, Inc. | Method and apparatus for forming a self-locking adjustable suture loop |
US20080140094A1 (en) * | 2006-12-11 | 2008-06-12 | Schwartz Herbert E | Unitary surgical device and method |
US20080167716A1 (en) * | 2001-07-16 | 2008-07-10 | Schwartz Hebert E | Cartilage repair apparatus and method |
US20080195145A1 (en) * | 2007-02-13 | 2008-08-14 | Bonutti Peter M | Tissue fixation system and method |
US20080200930A1 (en) * | 2004-05-07 | 2008-08-21 | Usgi Medical, Inc. | Apparatus for manipulating and securing tissue |
US20080208204A1 (en) * | 2007-02-13 | 2008-08-28 | Arthrex, Inc. | Intraarticular graft length gauge |
US20080228198A1 (en) * | 2007-03-13 | 2008-09-18 | Mitralign, Inc. | Suture cutter and method of cutting suture |
US20080234708A1 (en) * | 2007-03-22 | 2008-09-25 | Houser Kevin L | Surgical instruments |
US20080234709A1 (en) * | 2007-03-22 | 2008-09-25 | Houser Kevin L | Ultrasonic surgical instrument and cartilage and bone shaping blades therefor |
US20080234710A1 (en) * | 2007-03-22 | 2008-09-25 | Neurohr Mark A | Ultrasonic surgical instruments |
US7449025B1 (en) | 2002-12-17 | 2008-11-11 | O'donnell Pat D | Surgical instrument to secure body tissues |
US20090018574A1 (en) * | 2007-06-15 | 2009-01-15 | Zerusa Limited | Closure device |
US20090030311A1 (en) * | 2007-07-27 | 2009-01-29 | Stulen Foster B | Ultrasonic end effectors with increased active length |
US20090030438A1 (en) * | 2007-07-27 | 2009-01-29 | Stulen Foster B | Ultrasonic surgical instruments |
US20090030437A1 (en) * | 2007-07-27 | 2009-01-29 | Houser Kevin L | Surgical instruments |
US20090030351A1 (en) * | 2007-07-27 | 2009-01-29 | Wiener Eitan T | Multiple end effectors ultrasonic surgical instruments |
US20090030439A1 (en) * | 2007-07-27 | 2009-01-29 | Stulen Foster B | Ultrasonic surgical instruments |
US20090036912A1 (en) * | 2007-07-31 | 2009-02-05 | Wiener Eitan T | Ultrasonic surgical instruments |
US20090036914A1 (en) * | 2007-07-31 | 2009-02-05 | Houser Kevin L | Temperature controlled ultrasonic surgical instruments |
US20090036922A1 (en) * | 2004-08-31 | 2009-02-05 | Riskin Daniel J | Systems and methods for closing a tissue opening |
US20090036913A1 (en) * | 2007-07-31 | 2009-02-05 | Eitan Wiener | Surgical instruments |
US20090036911A1 (en) * | 2007-07-31 | 2009-02-05 | Stulen Foster B | Ultrasonic surgical instrument with modulator |
US20090088797A1 (en) * | 2007-09-28 | 2009-04-02 | Ethicon, Inc. | Surgical anchor device |
US20090105750A1 (en) * | 2007-10-05 | 2009-04-23 | Ethicon Endo-Surgery, Inc. | Ergonomic surgical instruments |
US20090112232A1 (en) * | 2007-10-31 | 2009-04-30 | Lawrence Crainich | Method for Deploying A Device For Gastric Volume Reduction |
US20090118762A1 (en) * | 2007-10-31 | 2009-05-07 | Lawrence Crainch | Disposable cartridge for use in a gastric volume reduction procedure |
US20090138042A1 (en) * | 2007-11-07 | 2009-05-28 | Raymond Thal | Adjustable loop knotless anchor |
US20090143806A1 (en) * | 2007-11-30 | 2009-06-04 | Ethicon Endo-Surgery, Inc. | Ultrasonic surgical blades |
US7594922B1 (en) | 2005-04-07 | 2009-09-29 | Medicine Lodge, Inc | System and method for meniscal repair through a meniscal capsular tunnel |
US7608092B1 (en) * | 2004-02-20 | 2009-10-27 | Biomet Sports Medicince, LLC | Method and apparatus for performing meniscus repair |
US20090318966A1 (en) * | 2004-06-02 | 2009-12-24 | Kfx Medical Corporation | System and method for attaching soft tissue to bone |
US20100049212A1 (en) * | 2008-04-02 | 2010-02-25 | David Caborn | Method and apparatus for meniscal repair |
WO2010065829A1 (en) * | 2008-12-05 | 2010-06-10 | Wilson-Cook Medical, Inc. | Hood method and device for material dissection |
US20100152772A1 (en) * | 2005-04-29 | 2010-06-17 | Gerard Brett | Interventional medical closure device |
USD618797S1 (en) | 2007-10-05 | 2010-06-29 | Ethicon Endo-Surgery, Inc. | Handle assembly for surgical instrument |
US20100191285A1 (en) * | 2003-06-11 | 2010-07-29 | Medicinelodge, Inc. Dba Imds Co-Innovation | Compact Line Locks and Methods |
EP2215973A1 (en) * | 2009-02-06 | 2010-08-11 | Karl Storz GmbH & Co. KG | Suture holding system |
EP2247252A2 (en) * | 2008-02-14 | 2010-11-10 | Robert C. Brown | Method for treating stress urinary incontinence and symptomatic pelvic relaxation |
US20100298743A1 (en) * | 2009-05-20 | 2010-11-25 | Ethicon Endo-Surgery, Inc. | Thermally-activated coupling arrangements and methods for attaching tools to ultrasonic surgical instruments |
US20100298851A1 (en) * | 2009-05-20 | 2010-11-25 | Ethicon Endo-Surgery, Inc. | Coupling arrangements and methods for attaching tools to ultrasonic surgical instruments |
US7857830B2 (en) | 2006-02-03 | 2010-12-28 | Biomet Sports Medicine, Llc | Soft tissue repair and conduit device |
US20100331870A1 (en) * | 2009-06-24 | 2010-12-30 | Ethicon Endo-Surgery, Inc. | Ultrasonic surgical instruments |
US20110015627A1 (en) * | 2009-07-15 | 2011-01-20 | Ethicon Endo-Surgery, Inc. | Impedance monitoring apparatus, system, and method for ultrasonic surgical instruments |
US20110015631A1 (en) * | 2009-07-15 | 2011-01-20 | Ethicon Endo-Surgery, Inc. | Electrosurgery generator for ultrasonic surgical instruments |
US20110015660A1 (en) * | 2009-07-15 | 2011-01-20 | Ethicon Endo-Surgery, Inc. | Rotating transducer mount for ultrasonic surgical instruments |
US20110022061A1 (en) * | 2009-07-24 | 2011-01-27 | Depuy Mitek, Inc. | Apparatus and method for repairing tissue |
US7901423B2 (en) | 2007-11-30 | 2011-03-08 | Ethicon Endo-Surgery, Inc. | Folded ultrasonic end effectors with increased active length |
US7905904B2 (en) | 2006-02-03 | 2011-03-15 | Biomet Sports Medicine, Llc | Soft tissue repair device and associated methods |
US7905903B2 (en) | 2006-02-03 | 2011-03-15 | Biomet Sports Medicine, Llc | Method for tissue fixation |
US7909851B2 (en) * | 2006-02-03 | 2011-03-22 | Biomet Sports Medicine, Llc | Soft tissue repair device and associated methods |
US20110071549A1 (en) * | 2008-04-02 | 2011-03-24 | David Caborn | Method and apparatus for meniscal repair |
US7914539B2 (en) | 2004-11-09 | 2011-03-29 | Biomet Sports Medicine, Llc | Tissue fixation device |
US20110077667A1 (en) * | 2008-06-06 | 2011-03-31 | Synthes Usa, Llc | Suture based tissue repair |
US7918869B2 (en) | 2004-05-07 | 2011-04-05 | Usgi Medical, Inc. | Methods and apparatus for performing endoluminal gastroplasty |
US20110087215A1 (en) * | 2009-10-09 | 2011-04-14 | Ethicon Endo-Surgery, Inc. | Surgical generator for ultrasonic and electrosurgical devices |
US20110106153A1 (en) * | 2006-02-03 | 2011-05-05 | Biomet Sports Medicine, Llc | Method and Apparatus for Sternal Closure |
US7942898B2 (en) | 2002-12-11 | 2011-05-17 | Usgi Medical, Inc. | Delivery systems and methods for gastric reduction |
US7942884B2 (en) | 2002-12-11 | 2011-05-17 | Usgi Medical, Inc. | Methods for reduction of a gastric lumen |
US7959650B2 (en) | 2006-09-29 | 2011-06-14 | Biomet Sports Medicine, Llc | Adjustable knotless loops |
US20110160856A1 (en) * | 2009-07-02 | 2011-06-30 | Medicinelodge, Inc. Dba Imds Co-Innovation | Systems and Methods for Zipknot ACL Fixation |
US20110185560A1 (en) * | 2008-08-18 | 2011-08-04 | Qioptiq Photonics Gmbh & Co. Kg | Method for producing an objective |
US20110196404A1 (en) * | 2010-02-11 | 2011-08-11 | Ethicon Endo-Surgery, Inc. | Ultrasonic surgical instruments with moving cutting implement |
US20110196405A1 (en) * | 2010-02-11 | 2011-08-11 | Ethicon Endo-Surgery, Inc. | Ultrasonic surgical instrument with comb-like tissue trimming device |
US20110196402A1 (en) * | 2010-02-11 | 2011-08-11 | Ethicon Endo-Surgery, Inc. | Dual purpose surgical instrument for cutting and coagulating tissue |
US20110196286A1 (en) * | 2010-02-11 | 2011-08-11 | Ethicon Endo-Surgery, Inc. | Ultrasonically powered surgical instruments with rotating cutting implement |
US20110196401A1 (en) * | 2010-02-11 | 2011-08-11 | Ethicon Endo-Surgery, Inc. | Ultrasonic surgical instruments with partially rotating blade and fixed pad arrangement |
US20110196287A1 (en) * | 2010-02-11 | 2011-08-11 | Ethicon Endo-Surgery, Inc. | Methods of using ultrasonically powered surgical instruments with rotatable cutting implements |
US8012205B2 (en) | 2001-07-16 | 2011-09-06 | Depuy Products, Inc. | Cartilage repair and regeneration device |
US20110218625A1 (en) * | 2006-02-03 | 2011-09-08 | Biomet Sports Medicine, Llc | Method and Apparatus for Fixation of an ACL Graft |
US8025896B2 (en) | 2001-07-16 | 2011-09-27 | Depuy Products, Inc. | Porous extracellular matrix scaffold and method |
US8058771B2 (en) | 2008-08-06 | 2011-11-15 | Ethicon Endo-Surgery, Inc. | Ultrasonic device for cutting and coagulating with stepped output |
US8057498B2 (en) | 2007-11-30 | 2011-11-15 | Ethicon Endo-Surgery, Inc. | Ultrasonic surgical instrument blades |
US8062334B2 (en) | 2004-06-02 | 2011-11-22 | Kfx Medical Corporation | Suture anchor |
US8088130B2 (en) | 2006-02-03 | 2012-01-03 | Biomet Sports Medicine, Llc | Method and apparatus for coupling soft tissue to a bone |
US8092529B2 (en) | 2001-07-16 | 2012-01-10 | Depuy Products, Inc. | Meniscus regeneration device |
US8118836B2 (en) | 2004-11-05 | 2012-02-21 | Biomet Sports Medicine, Llc | Method and apparatus for coupling soft tissue to a bone |
US20120046747A1 (en) * | 2004-09-07 | 2012-02-23 | Medicinelodge, Inc. Dba Imds Co-Innovation | Systems and methods for zipknot acl fixation |
US8128640B2 (en) | 2005-02-07 | 2012-03-06 | Ivy Sports Medicine LLC | System and method for all-inside suture fixation for implant attachment and soft tissue repair |
US8128658B2 (en) | 2004-11-05 | 2012-03-06 | Biomet Sports Medicine, Llc | Method and apparatus for coupling soft tissue to bone |
US8137382B2 (en) | 2004-11-05 | 2012-03-20 | Biomet Sports Medicine, Llc | Method and apparatus for coupling anatomical features |
US8216252B2 (en) | 2004-05-07 | 2012-07-10 | Usgi Medical, Inc. | Tissue manipulation and securement system |
US8226675B2 (en) | 2007-03-22 | 2012-07-24 | Ethicon Endo-Surgery, Inc. | Surgical instruments |
US8251998B2 (en) | 2006-08-16 | 2012-08-28 | Biomet Sports Medicine, Llc | Chondral defect repair |
US8298262B2 (en) | 2006-02-03 | 2012-10-30 | Biomet Sports Medicine, Llc | Method for tissue fixation |
US8303604B2 (en) | 2004-11-05 | 2012-11-06 | Biomet Sports Medicine, Llc | Soft tissue repair device and method |
US8323315B2 (en) | 1998-12-30 | 2012-12-04 | Depuy Mitek, Inc. | Suture locking device |
US8337537B2 (en) | 2001-07-16 | 2012-12-25 | Depuy Products, Inc. | Device from naturally occurring biologically derived materials |
US8343227B2 (en) | 2009-05-28 | 2013-01-01 | Biomet Manufacturing Corp. | Knee prosthesis assembly with ligament link |
US8361113B2 (en) | 2006-02-03 | 2013-01-29 | Biomet Sports Medicine, Llc | Method and apparatus for coupling soft tissue to a bone |
US8366787B2 (en) | 2000-08-04 | 2013-02-05 | Depuy Products, Inc. | Hybrid biologic-synthetic bioabsorbable scaffolds |
WO2013062933A1 (en) * | 2011-10-24 | 2013-05-02 | C.R. Bard, Inc. | Instruments for delivering transfascial sutures, transfascial suture assemblies and methods of transfascial suturing |
US8444657B2 (en) | 2004-05-07 | 2013-05-21 | Usgi Medical, Inc. | Apparatus and methods for rapid deployment of tissue anchors |
US8469981B2 (en) | 2010-02-11 | 2013-06-25 | Ethicon Endo-Surgery, Inc. | Rotatable cutting implement arrangements for ultrasonic surgical instruments |
US20130178898A1 (en) * | 2011-07-06 | 2013-07-11 | Imds Corporation | Tissue approximation |
US8496657B2 (en) | 2006-02-07 | 2013-07-30 | P Tech, Llc. | Methods for utilizing vibratory energy to weld, stake and/or remove implants |
USD687549S1 (en) | 2011-10-24 | 2013-08-06 | Ethicon Endo-Surgery, Inc. | Surgical instrument |
US8500818B2 (en) | 2006-09-29 | 2013-08-06 | Biomet Manufacturing, Llc | Knee prosthesis assembly with ligament link |
US8506597B2 (en) | 2011-10-25 | 2013-08-13 | Biomet Sports Medicine, Llc | Method and apparatus for interosseous membrane reconstruction |
US8523869B2 (en) | 2005-05-20 | 2013-09-03 | Smith & Nephew, Inc. | Patello-femoral joint implant and instrumentation |
US8546996B2 (en) | 2008-08-06 | 2013-10-01 | Ethicon Endo-Surgery, Inc. | Devices and techniques for cutting and coagulating tissue |
USD691265S1 (en) | 2011-08-23 | 2013-10-08 | Covidien Ag | Control assembly for portable surgical device |
US8556977B2 (en) | 1999-10-20 | 2013-10-15 | Anulex Technologies, Inc. | Tissue anchoring system and method |
US8562647B2 (en) | 2006-09-29 | 2013-10-22 | Biomet Sports Medicine, Llc | Method and apparatus for securing soft tissue to bone |
US8562645B2 (en) | 2006-09-29 | 2013-10-22 | Biomet Sports Medicine, Llc | Method and apparatus for forming a self-locking adjustable loop |
US8574235B2 (en) | 2006-02-03 | 2013-11-05 | Biomet Sports Medicine, Llc | Method for trochanteric reattachment |
US8579928B2 (en) | 2010-02-11 | 2013-11-12 | Ethicon Endo-Surgery, Inc. | Outer sheath and blade arrangements for ultrasonic surgical instruments |
US8652171B2 (en) | 2006-02-03 | 2014-02-18 | Biomet Sports Medicine, Llc | Method and apparatus for soft tissue fixation |
US8652172B2 (en) | 2006-02-03 | 2014-02-18 | Biomet Sports Medicine, Llc | Flexible anchors for tissue fixation |
CN103607963A (en) * | 2011-06-20 | 2014-02-26 | 伊西康公司 | Method and device for approximating tissue |
US8672969B2 (en) | 2006-09-29 | 2014-03-18 | Biomet Sports Medicine, Llc | Fracture fixation device |
US20140081399A1 (en) * | 2009-03-31 | 2014-03-20 | Arthrex, Inc. | Adjustable suture-button construct for knotless stabilization of cranial cruciate deficient ligament stifle |
US8747439B2 (en) | 2000-03-13 | 2014-06-10 | P Tech, Llc | Method of using ultrasonic vibration to secure body tissue with fastening element |
US8771352B2 (en) | 2011-05-17 | 2014-07-08 | Biomet Sports Medicine, Llc | Method and apparatus for tibial fixation of an ACL graft |
US8790370B2 (en) | 2012-03-30 | 2014-07-29 | Depuy Mitek, Llc | Surgical filament assemblies |
US8790356B2 (en) | 2010-06-09 | 2014-07-29 | C.R. Bard, Inc. | Instruments for delivering transfascial sutures, transfascial suture assemblies, and methods of transfascial suturing |
US8801783B2 (en) | 2006-09-29 | 2014-08-12 | Biomet Sports Medicine, Llc | Prosthetic ligament system for knee joint |
US8808329B2 (en) | 1998-02-06 | 2014-08-19 | Bonutti Skeletal Innovations Llc | Apparatus and method for securing a portion of a body |
US8814902B2 (en) | 2000-05-03 | 2014-08-26 | Bonutti Skeletal Innovations Llc | Method of securing body tissue |
US8814905B2 (en) | 2010-11-23 | 2014-08-26 | Depuy Mitek, Llc | Surgical filament snare assemblies |
US8821544B2 (en) | 2010-11-23 | 2014-09-02 | Depuy Mitek, Llc | Surgical filament snare assemblies |
US8821543B2 (en) | 2010-12-23 | 2014-09-02 | Depuy Mitek, Llc | Adjustable anchor systems and methods |
US8840645B2 (en) | 2004-11-05 | 2014-09-23 | Biomet Sports Medicine, Llc | Method and apparatus for coupling soft tissue to a bone |
US8845699B2 (en) | 1999-08-09 | 2014-09-30 | Bonutti Skeletal Innovations Llc | Method of securing tissue |
US8870916B2 (en) | 2006-07-07 | 2014-10-28 | USGI Medical, Inc | Low profile tissue anchors, tissue anchor systems, and methods for their delivery and use |
US8888809B2 (en) | 2010-10-01 | 2014-11-18 | Ethicon Endo-Surgery, Inc. | Surgical instrument with jaw member |
US8894684B2 (en) | 2012-05-07 | 2014-11-25 | Medos International Sàrl | Systems, devices, and methods for securing tissue using a suture having one or more protrusions |
US8932330B2 (en) | 2000-03-13 | 2015-01-13 | P Tech, Llc | Method and device for securing body tissue |
US8936621B2 (en) | 2006-02-03 | 2015-01-20 | Biomet Sports Medicine, Llc | Method and apparatus for forming a self-locking adjustable loop |
US8945211B2 (en) | 2008-09-12 | 2015-02-03 | Mitralign, Inc. | Tissue plication device and method for its use |
US8951272B2 (en) | 2010-02-11 | 2015-02-10 | Ethicon Endo-Surgery, Inc. | Seal arrangements for ultrasonically powered surgical instruments |
US8979890B2 (en) | 2010-10-01 | 2015-03-17 | Ethicon Endo-Surgery, Inc. | Surgical instrument with jaw member |
US8998949B2 (en) | 2004-11-09 | 2015-04-07 | Biomet Sports Medicine, Llc | Soft tissue conduit device |
US9017381B2 (en) | 2007-04-10 | 2015-04-28 | Biomet Sports Medicine, Llc | Adjustable knotless loops |
US9039721B2 (en) | 2011-11-07 | 2015-05-26 | C.R. Bard, Inc. | Instruments for delivering transfascial sutures and methods of transfascial suturing |
US9060764B2 (en) | 2012-05-07 | 2015-06-23 | Medos International Sàrl | Systems, devices, and methods for securing tissue |
US9060767B2 (en) | 2003-04-30 | 2015-06-23 | P Tech, Llc | Tissue fastener and methods for using same |
US9060763B2 (en) | 2012-05-07 | 2015-06-23 | Medos International Sàrl | Systems, devices, and methods for securing tissue |
US9060751B2 (en) | 2010-12-30 | 2015-06-23 | Vivasure Medical Limited | Surgical closure systems and methods |
US9078648B2 (en) | 2011-11-07 | 2015-07-14 | C.R. Bard, Inc. | Instruments for delivering transfascial sutures and methods of transfascial suturing |
US9078644B2 (en) | 2006-09-29 | 2015-07-14 | Biomet Sports Medicine, Llc | Fracture fixation device |
US9089323B2 (en) | 2005-02-22 | 2015-07-28 | P Tech, Llc | Device and method for securing body tissue |
US9095331B2 (en) | 2010-12-23 | 2015-08-04 | Medos International Sàrl | Adjustable anchor systems and methods |
US9095442B2 (en) | 1999-10-20 | 2015-08-04 | Krt Investors, Inc. | Method and apparatus for the treatment of the intervertebral disc annulus |
US9095367B2 (en) | 2012-10-22 | 2015-08-04 | Ethicon Endo-Surgery, Inc. | Flexible harmonic waveguides/blades for surgical instruments |
US9114025B2 (en) | 1999-10-20 | 2015-08-25 | Krt Investors, Inc. | Methods and devices for spinal disc annulus reconstruction and repair |
US9125707B2 (en) | 2011-01-06 | 2015-09-08 | Smith & Nephew, Inc. | Cannulated guide tools |
EP2548519B1 (en) | 2011-07-21 | 2015-09-16 | Arthrex, Inc. | Knotless suture constructs |
US9138222B2 (en) | 2000-03-13 | 2015-09-22 | P Tech, Llc | Method and device for securing body tissue |
US9149267B2 (en) | 2006-02-03 | 2015-10-06 | Biomet Sports Medicine, Llc | Method and apparatus for coupling soft tissue to a bone |
US9149281B2 (en) | 2002-03-20 | 2015-10-06 | P Tech, Llc | Robotic system for engaging a fastener with body tissue |
US9168054B2 (en) | 2009-10-09 | 2015-10-27 | Ethicon Endo-Surgery, Inc. | Surgical generator for ultrasonic and electrosurgical devices |
US9173647B2 (en) | 2004-10-26 | 2015-11-03 | P Tech, Llc | Tissue fixation system |
US9192373B2 (en) | 2012-12-27 | 2015-11-24 | Medos International Sàrl | Surgical constructs and methods for securing tissue |
US9192372B2 (en) | 2008-10-14 | 2015-11-24 | Krt Investors, Inc. | Method for the treatment of tissue |
US9198714B2 (en) | 2012-06-29 | 2015-12-01 | Ethicon Endo-Surgery, Inc. | Haptic feedback devices for surgical robot |
US9220493B2 (en) | 2009-02-06 | 2015-12-29 | Karl Storz Gmbh & Co. Kg | Suture anchor kit |
US9226767B2 (en) | 2012-06-29 | 2016-01-05 | Ethicon Endo-Surgery, Inc. | Closed feedback control for electrosurgical device |
US9226766B2 (en) | 2012-04-09 | 2016-01-05 | Ethicon Endo-Surgery, Inc. | Serial communication protocol for medical device |
US9232979B2 (en) | 2012-02-10 | 2016-01-12 | Ethicon Endo-Surgery, Inc. | Robotically controlled surgical instrument |
US9237921B2 (en) | 2012-04-09 | 2016-01-19 | Ethicon Endo-Surgery, Inc. | Devices and techniques for cutting and coagulating tissue |
US9241728B2 (en) | 2013-03-15 | 2016-01-26 | Ethicon Endo-Surgery, Inc. | Surgical instrument with multiple clamping mechanisms |
US9241731B2 (en) | 2012-04-09 | 2016-01-26 | Ethicon Endo-Surgery, Inc. | Rotatable electrical connection for ultrasonic surgical instruments |
US9259217B2 (en) | 2012-01-03 | 2016-02-16 | Biomet Manufacturing, Llc | Suture Button |
US9259234B2 (en) | 2010-02-11 | 2016-02-16 | Ethicon Endo-Surgery, Llc | Ultrasonic surgical instruments with rotatable blade and hollow sheath arrangements |
US9265514B2 (en) | 2012-04-17 | 2016-02-23 | Miteas Ltd. | Manipulator for grasping tissue |
WO2016028978A1 (en) * | 2014-08-20 | 2016-02-25 | Yale University | Assemblies and methodologies for the repair of hernias |
US9271766B2 (en) | 2004-10-26 | 2016-03-01 | P Tech, Llc | Devices and methods for stabilizing tissue and implants |
US9271713B2 (en) | 2006-02-03 | 2016-03-01 | Biomet Sports Medicine, Llc | Method and apparatus for tensioning a suture |
US9283045B2 (en) | 2012-06-29 | 2016-03-15 | Ethicon Endo-Surgery, Llc | Surgical instruments with fluid management system |
US9301760B2 (en) | 2011-05-03 | 2016-04-05 | Dermaclip Us, Llc | Devices for securely closing tissue openings with minimized scarring |
US9314241B2 (en) | 2011-11-10 | 2016-04-19 | Biomet Sports Medicine, Llc | Apparatus for coupling soft tissue to a bone |
US9326788B2 (en) | 2012-06-29 | 2016-05-03 | Ethicon Endo-Surgery, Llc | Lockout mechanism for use with robotic electrosurgical device |
US20160120535A1 (en) * | 2014-10-29 | 2016-05-05 | Smith & Nephew, Inc. | Modular tissue repair kit and devices and method related thereto |
US9345567B2 (en) | 2012-05-07 | 2016-05-24 | Medos International Sàrl | Systems, devices, and methods for securing tissue using snare assemblies and soft anchors |
US9351754B2 (en) | 2012-06-29 | 2016-05-31 | Ethicon Endo-Surgery, Llc | Ultrasonic surgical instruments with distally positioned jaw assemblies |
US9357991B2 (en) | 2011-11-03 | 2016-06-07 | Biomet Sports Medicine, Llc | Method and apparatus for stitching tendons |
US9358111B2 (en) | 2007-03-13 | 2016-06-07 | Mitralign, Inc. | Tissue anchors, systems and methods, and devices |
US9370350B2 (en) | 2011-11-10 | 2016-06-21 | Biomet Sports Medicine, Llc | Apparatus for coupling soft tissue to a bone |
US20160174963A1 (en) * | 2013-07-30 | 2016-06-23 | Arcuro Medical Ltd. | Joining devices, kits and methods |
US9381013B2 (en) | 2011-11-10 | 2016-07-05 | Biomet Sports Medicine, Llc | Method for coupling soft tissue to a bone |
US9393037B2 (en) | 2012-06-29 | 2016-07-19 | Ethicon Endo-Surgery, Llc | Surgical instruments with articulating shafts |
US9408599B2 (en) | 2006-02-03 | 2016-08-09 | Biomet Sports Medicine, Llc | Method and apparatus for coupling soft tissue to a bone |
US9408622B2 (en) | 2012-06-29 | 2016-08-09 | Ethicon Endo-Surgery, Llc | Surgical instruments with articulating shafts |
US9421005B2 (en) | 2006-02-07 | 2016-08-23 | P Tech, Llc | Methods and devices for intracorporeal bonding of implants with thermal energy |
US20160242761A1 (en) * | 2014-06-15 | 2016-08-25 | Anchora Medical Ltd. | Apparatus and method for suturing a tissue |
US9439642B2 (en) | 2006-02-07 | 2016-09-13 | P Tech, Llc | Methods and devices for utilizing bondable materials |
US9439668B2 (en) | 2012-04-09 | 2016-09-13 | Ethicon Endo-Surgery, Llc | Switch arrangements for ultrasonic surgical instruments |
US9445806B2 (en) | 2009-02-06 | 2016-09-20 | Karl Storz Gmbh & Co. Kg | Suture holder delivery system |
US9463012B2 (en) | 2004-10-26 | 2016-10-11 | P Tech, Llc | Apparatus for guiding and positioning an implant |
US9480565B2 (en) * | 2015-02-02 | 2016-11-01 | On-X Life Technologies, Inc. | Rapid deployment artificial chordae tendinae system |
US9510822B2 (en) | 2014-12-04 | 2016-12-06 | Coloplast A/S | Tissue anchor |
US9517060B2 (en) | 2012-09-27 | 2016-12-13 | Ethicon, Inc. | Method and device for approximating tissue |
US9538998B2 (en) | 2006-02-03 | 2017-01-10 | Biomet Sports Medicine, Llc | Method and apparatus for fracture fixation |
US9572558B2 (en) | 2012-02-29 | 2017-02-21 | Vivasure Medical Limited | Devices and methods for delivering implants for percutaneous perforation closure |
US9615822B2 (en) | 2014-05-30 | 2017-04-11 | Biomet Sports Medicine, Llc | Insertion tools and method for soft anchor |
US9700291B2 (en) | 2014-06-03 | 2017-07-11 | Biomet Sports Medicine, Llc | Capsule retractor |
US9700333B2 (en) | 2014-06-30 | 2017-07-11 | Ethicon Llc | Surgical instrument with variable tissue compression |
US9707027B2 (en) | 2010-05-21 | 2017-07-18 | Ethicon Endo-Surgery, Llc | Medical device |
US20170215864A1 (en) * | 2016-02-01 | 2017-08-03 | DePuy Synthes Products, Inc. | Tissue augmentation constructs for use with soft tissue fixation repair systems and methods |
US9724118B2 (en) | 2012-04-09 | 2017-08-08 | Ethicon Endo-Surgery, Llc | Techniques for cutting and coagulating tissue for ultrasonic surgical instruments |
US9737293B2 (en) | 2013-03-15 | 2017-08-22 | Medos International Sàrl | Surgical constructs with collapsing suture loop and methods for securing tissue |
US9750496B2 (en) | 2002-08-27 | 2017-09-05 | P Tech, Llc | System for securing a portion of a body |
US9757119B2 (en) | 2013-03-08 | 2017-09-12 | Biomet Sports Medicine, Llc | Visual aid for identifying suture limbs arthroscopically |
US9763655B2 (en) | 2012-09-20 | 2017-09-19 | Medos International Sarl | Systems, devices, and methods for securing tissue using hard anchors |
US9770238B2 (en) | 2001-12-03 | 2017-09-26 | P Tech, Llc | Magnetic positioning apparatus |
US20170273680A1 (en) * | 2016-02-01 | 2017-09-28 | DePuy Synthes Products, Inc. | Tissue augmentation tacks for use with soft tissue fixation repair systems and methods |
US20170303907A1 (en) * | 2016-04-20 | 2017-10-26 | DePuy Synthes Products, Inc. | Meniscal repair devices, systems, and methods |
US9801708B2 (en) | 2004-11-05 | 2017-10-31 | Biomet Sports Medicine, Llc | Method and apparatus for coupling soft tissue to a bone |
US9820768B2 (en) | 2012-06-29 | 2017-11-21 | Ethicon Llc | Ultrasonic surgical instruments with control mechanisms |
US9826992B2 (en) | 2007-12-21 | 2017-11-28 | Smith & Nephew, Inc. | Multiple portal guide |
CN107427297A (en) * | 2015-02-06 | 2017-12-01 | 医疗创新开发公司 | Skin expansion system |
US9850013B2 (en) | 2013-03-15 | 2017-12-26 | Vivasure Medical Limited | Loading devices and methods for percutaneous perforation closure systems |
US9888916B2 (en) | 2004-03-09 | 2018-02-13 | P Tech, Llc | Method and device for securing body tissue |
US9888936B2 (en) | 2010-09-27 | 2018-02-13 | Smith & Nephew, Inc. | Device and methods for use during arthroscopic surgery |
US9913636B2 (en) | 2007-12-21 | 2018-03-13 | Smith & Nephew, Inc. | Multiple portal guide |
US9918826B2 (en) | 2006-09-29 | 2018-03-20 | Biomet Sports Medicine, Llc | Scaffold for spring ligament repair |
US9918775B2 (en) | 2011-04-12 | 2018-03-20 | Covidien Lp | Systems and methods for calibrating power measurements in an electrosurgical generator |
US9918827B2 (en) | 2013-03-14 | 2018-03-20 | Biomet Sports Medicine, Llc | Scaffold for spring ligament repair |
US9924938B2 (en) | 2011-11-07 | 2018-03-27 | C.R. Bard, Inc. | Instruments for delivering transfascial sutures and methods of transfascial suturing |
US9936940B2 (en) | 2013-06-07 | 2018-04-10 | Biomet Sports Medicine, Llc | Method and apparatus for coupling soft tissue to bone |
US9949734B2 (en) | 2012-10-31 | 2018-04-24 | Suture Concepts Inc. | Method and apparatus for closing a fissure in the annulus of an intervertebral disc, and/or for effecting other anatomical repairs and/or fixations |
US9955980B2 (en) | 2015-02-24 | 2018-05-01 | Biomet Sports Medicine, Llc | Anatomic soft tissue repair |
US10034704B2 (en) | 2015-06-30 | 2018-07-31 | Ethicon Llc | Surgical instrument with user adaptable algorithms |
US10034684B2 (en) | 2015-06-15 | 2018-07-31 | Ethicon Llc | Apparatus and method for dissecting and coagulating tissue |
US10039543B2 (en) | 2014-08-22 | 2018-08-07 | Biomet Sports Medicine, Llc | Non-sliding soft anchor |
US10058393B2 (en) | 2015-10-21 | 2018-08-28 | P Tech, Llc | Systems and methods for navigation and visualization |
US10076377B2 (en) | 2013-01-05 | 2018-09-18 | P Tech, Llc | Fixation systems and methods |
US10130354B2 (en) | 2015-08-17 | 2018-11-20 | Arthrex, Inc. | Limited sliding suture in suture anchor |
US10136886B2 (en) | 2013-12-20 | 2018-11-27 | Biomet Sports Medicine, Llc | Knotless soft tissue devices and techniques |
US10154852B2 (en) | 2015-07-01 | 2018-12-18 | Ethicon Llc | Ultrasonic surgical blade with improved cutting and coagulation features |
US10172669B2 (en) | 2009-10-09 | 2019-01-08 | Ethicon Llc | Surgical instrument comprising an energy trigger lockout |
US10179022B2 (en) | 2015-12-30 | 2019-01-15 | Ethicon Llc | Jaw position impedance limiter for electrosurgical instrument |
US10194973B2 (en) | 2015-09-30 | 2019-02-05 | Ethicon Llc | Generator for digitally generating electrical signal waveforms for electrosurgical and ultrasonic surgical instruments |
US10201365B2 (en) | 2012-10-22 | 2019-02-12 | Ethicon Llc | Surgeon feedback sensing and display methods |
US10206668B2 (en) | 2014-12-15 | 2019-02-19 | Vivasure Medical Limited | Implantable sealable member with mesh layer |
US10219812B2 (en) | 2010-11-03 | 2019-03-05 | Smith & Nephew, Inc. | Drill guide |
US10226273B2 (en) | 2013-03-14 | 2019-03-12 | Ethicon Llc | Mechanical fasteners for use with surgical energy devices |
US10245169B2 (en) * | 2014-06-20 | 2019-04-02 | Endo Tools Therapeutics S.A. | Assembly for securing gastrointestinal tissue folds |
US10245064B2 (en) | 2016-07-12 | 2019-04-02 | Ethicon Llc | Ultrasonic surgical instrument with piezoelectric central lumen transducer |
US10251664B2 (en) | 2016-01-15 | 2019-04-09 | Ethicon Llc | Modular battery powered handheld surgical instrument with multi-function motor via shifting gear assembly |
US10278721B2 (en) | 2010-07-22 | 2019-05-07 | Ethicon Llc | Electrosurgical instrument with separate closure and cutting members |
USD847990S1 (en) | 2016-08-16 | 2019-05-07 | Ethicon Llc | Surgical instrument |
US10285723B2 (en) | 2016-08-09 | 2019-05-14 | Ethicon Llc | Ultrasonic surgical blade with improved heel portion |
US10285724B2 (en) | 2014-07-31 | 2019-05-14 | Ethicon Llc | Actuation mechanisms and load adjustment assemblies for surgical instruments |
US10299829B2 (en) | 2016-11-07 | 2019-05-28 | Ronald Yamada | Tissue repair system |
US10314638B2 (en) | 2015-04-07 | 2019-06-11 | Ethicon Llc | Articulating radio frequency (RF) tissue seal with articulating state sensing |
US10321950B2 (en) | 2015-03-17 | 2019-06-18 | Ethicon Llc | Managing tissue treatment |
US10342602B2 (en) | 2015-03-17 | 2019-07-09 | Ethicon Llc | Managing tissue treatment |
US10349999B2 (en) | 2014-03-31 | 2019-07-16 | Ethicon Llc | Controlling impedance rise in electrosurgical medical devices |
US10357303B2 (en) | 2015-06-30 | 2019-07-23 | Ethicon Llc | Translatable outer tube for sealing using shielded lap chole dissector |
US10357260B2 (en) | 2015-11-02 | 2019-07-23 | First Ray, LLC | Orthopedic fastener, retainer, and guide methods |
US10376305B2 (en) | 2016-08-05 | 2019-08-13 | Ethicon Llc | Methods and systems for advanced harmonic energy |
US10376367B2 (en) | 2015-07-02 | 2019-08-13 | First Ray, LLC | Orthopedic fasteners, instruments and methods |
US10420580B2 (en) | 2016-08-25 | 2019-09-24 | Ethicon Llc | Ultrasonic transducer for surgical instrument |
US10433826B2 (en) | 2014-12-15 | 2019-10-08 | Vivasure Medical Limited | Closure apparatus with flexible sealable member and flexible support member |
US10433900B2 (en) | 2011-07-22 | 2019-10-08 | Ethicon Llc | Surgical instruments for tensioning tissue |
US10441345B2 (en) | 2009-10-09 | 2019-10-15 | Ethicon Llc | Surgical generator for ultrasonic and electrosurgical devices |
US10456193B2 (en) | 2016-05-03 | 2019-10-29 | Ethicon Llc | Medical device with a bilateral jaw configuration for nerve stimulation |
US10463421B2 (en) | 2014-03-27 | 2019-11-05 | Ethicon Llc | Two stage trigger, clamp and cut bipolar vessel sealer |
US10485607B2 (en) | 2016-04-29 | 2019-11-26 | Ethicon Llc | Jaw structure with distal closure for electrosurgical instruments |
US10517587B2 (en) | 2006-02-03 | 2019-12-31 | Biomet Sports Medicine, Llc | Method and apparatus for forming a self-locking adjustable loop |
US10524854B2 (en) | 2010-07-23 | 2020-01-07 | Ethicon Llc | Surgical instrument |
US10537352B2 (en) | 2004-10-08 | 2020-01-21 | Ethicon Llc | Tissue pads for use with surgical instruments |
US10555769B2 (en) | 2016-02-22 | 2020-02-11 | Ethicon Llc | Flexible circuits for electrosurgical instrument |
US10575892B2 (en) | 2015-12-31 | 2020-03-03 | Ethicon Llc | Adapter for electrical surgical instruments |
US10595929B2 (en) | 2015-03-24 | 2020-03-24 | Ethicon Llc | Surgical instruments with firing system overload protection mechanisms |
US10595930B2 (en) | 2015-10-16 | 2020-03-24 | Ethicon Llc | Electrode wiping surgical device |
US10603064B2 (en) | 2016-11-28 | 2020-03-31 | Ethicon Llc | Ultrasonic transducer |
US10603117B2 (en) | 2017-06-28 | 2020-03-31 | Ethicon Llc | Articulation state detection mechanisms |
WO2020069486A1 (en) * | 2018-09-28 | 2020-04-02 | Conmed Corporation | System for repairing soft tissue tears |
US10639092B2 (en) | 2014-12-08 | 2020-05-05 | Ethicon Llc | Electrode configurations for surgical instruments |
US10646269B2 (en) | 2016-04-29 | 2020-05-12 | Ethicon Llc | Non-linear jaw gap for electrosurgical instruments |
USRE47996E1 (en) | 2009-10-09 | 2020-05-19 | Ethicon Llc | Surgical generator for ultrasonic and electrosurgical devices |
US10653409B2 (en) | 2015-12-04 | 2020-05-19 | Crossroads Extremity Systems, Llc | Devices and methods for anchoring tissue |
US10702329B2 (en) | 2016-04-29 | 2020-07-07 | Ethicon Llc | Jaw structure with distal post for electrosurgical instruments |
US10716615B2 (en) | 2016-01-15 | 2020-07-21 | Ethicon Llc | Modular battery powered handheld surgical instrument with curved end effectors having asymmetric engagement between jaw and blade |
US10751117B2 (en) | 2016-09-23 | 2020-08-25 | Ethicon Llc | Electrosurgical instrument with fluid diverter |
US10751109B2 (en) | 2014-12-22 | 2020-08-25 | Ethicon Llc | High power battery powered RF amplifier topology |
US10765470B2 (en) | 2015-06-30 | 2020-09-08 | Ethicon Llc | Surgical system with user adaptable techniques employing simultaneous energy modalities based on tissue parameters |
US10772622B2 (en) | 2016-10-27 | 2020-09-15 | Smith & Nephew, Inc. | Tissue repair device |
US10779876B2 (en) | 2011-10-24 | 2020-09-22 | Ethicon Llc | Battery powered surgical instrument |
US10779848B2 (en) | 2006-01-20 | 2020-09-22 | Ethicon Llc | Ultrasound medical instrument having a medical ultrasonic blade |
US10779845B2 (en) | 2012-06-29 | 2020-09-22 | Ethicon Llc | Ultrasonic surgical instruments with distally positioned transducers |
US10779879B2 (en) | 2014-03-18 | 2020-09-22 | Ethicon Llc | Detecting short circuits in electrosurgical medical devices |
US10786235B2 (en) | 2012-10-31 | 2020-09-29 | Anchor Innovation Medical, Inc. | Method and apparatus for closing a fissure in the annulus of an intervertebral disc, and/or for effecting other anatomical repairs and/or fixations |
US10799284B2 (en) | 2017-03-15 | 2020-10-13 | Ethicon Llc | Electrosurgical instrument with textured jaws |
US10820920B2 (en) | 2017-07-05 | 2020-11-03 | Ethicon Llc | Reusable ultrasonic medical devices and methods of their use |
US10835307B2 (en) | 2001-06-12 | 2020-11-17 | Ethicon Llc | Modular battery powered handheld surgical instrument containing elongated multi-layered shaft |
US10842522B2 (en) | 2016-07-15 | 2020-11-24 | Ethicon Llc | Ultrasonic surgical instruments having offset blades |
US10856934B2 (en) | 2016-04-29 | 2020-12-08 | Ethicon Llc | Electrosurgical instrument with electrically conductive gap setting and tissue engaging members |
US10856896B2 (en) | 2005-10-14 | 2020-12-08 | Ethicon Llc | Ultrasonic device for cutting and coagulating |
US10856929B2 (en) | 2014-01-07 | 2020-12-08 | Ethicon Llc | Harvesting energy from a surgical generator |
US10874418B2 (en) | 2004-02-27 | 2020-12-29 | Ethicon Llc | Ultrasonic surgical shears and method for sealing a blood vessel using same |
US10881449B2 (en) | 2012-09-28 | 2021-01-05 | Ethicon Llc | Multi-function bi-polar forceps |
US10893883B2 (en) | 2016-07-13 | 2021-01-19 | Ethicon Llc | Ultrasonic assembly for use with ultrasonic surgical instruments |
US10898256B2 (en) | 2015-06-30 | 2021-01-26 | Ethicon Llc | Surgical system with user adaptable techniques based on tissue impedance |
US10912580B2 (en) | 2013-12-16 | 2021-02-09 | Ethicon Llc | Medical device |
US10912551B2 (en) | 2015-03-31 | 2021-02-09 | Biomet Sports Medicine, Llc | Suture anchor with soft anchor of electrospun fibers |
US10912603B2 (en) | 2013-11-08 | 2021-02-09 | Ethicon Llc | Electrosurgical devices |
US10918373B2 (en) | 2013-08-31 | 2021-02-16 | Edwards Lifesciences Corporation | Devices and methods for locating and implanting tissue anchors at mitral valve commissure |
US10925659B2 (en) | 2013-09-13 | 2021-02-23 | Ethicon Llc | Electrosurgical (RF) medical instruments for cutting and coagulating tissue |
US10932769B2 (en) | 2016-05-26 | 2021-03-02 | Ivy Sports Medicine, Llc | System and method for all-inside suture fixation for implant attachment and soft tissue repair |
US10952759B2 (en) | 2016-08-25 | 2021-03-23 | Ethicon Llc | Tissue loading of a surgical instrument |
US10959806B2 (en) | 2015-12-30 | 2021-03-30 | Ethicon Llc | Energized medical device with reusable handle |
US10959771B2 (en) | 2015-10-16 | 2021-03-30 | Ethicon Llc | Suction and irrigation sealing grasper |
US10987156B2 (en) | 2016-04-29 | 2021-04-27 | Ethicon Llc | Electrosurgical instrument with electrically conductive gap setting member and electrically insulative tissue engaging members |
US10987123B2 (en) | 2012-06-28 | 2021-04-27 | Ethicon Llc | Surgical instruments with articulating shafts |
US11020140B2 (en) | 2015-06-17 | 2021-06-01 | Cilag Gmbh International | Ultrasonic surgical blade for use with ultrasonic surgical instruments |
US11033292B2 (en) | 2013-12-16 | 2021-06-15 | Cilag Gmbh International | Medical device |
US11033323B2 (en) | 2017-09-29 | 2021-06-15 | Cilag Gmbh International | Systems and methods for managing fluid and suction in electrosurgical systems |
US11033325B2 (en) | 2017-02-16 | 2021-06-15 | Cilag Gmbh International | Electrosurgical instrument with telescoping suction port and debris cleaner |
US11051873B2 (en) | 2015-06-30 | 2021-07-06 | Cilag Gmbh International | Surgical system with user adaptable techniques employing multiple energy modalities based on tissue parameters |
US11090104B2 (en) | 2009-10-09 | 2021-08-17 | Cilag Gmbh International | Surgical generator for ultrasonic and electrosurgical devices |
US11103350B2 (en) | 2016-06-01 | 2021-08-31 | On-X Life Technologies, Inc. | Pull-through chordae tendineae system |
US11129670B2 (en) | 2016-01-15 | 2021-09-28 | Cilag Gmbh International | Modular battery powered handheld surgical instrument with selective application of energy based on button displacement, intensity, or local tissue characterization |
US11129669B2 (en) | 2015-06-30 | 2021-09-28 | Cilag Gmbh International | Surgical system with user adaptable techniques based on tissue type |
US11229471B2 (en) | 2016-01-15 | 2022-01-25 | Cilag Gmbh International | Modular battery powered handheld surgical instrument with selective application of energy based on tissue characterization |
US20220031300A1 (en) * | 2020-07-28 | 2022-02-03 | Mentor Worldwide Llc | Quick, one-handed interrupted suture fixation for approximating tissue without the need to tie knots |
US11246638B2 (en) | 2006-05-03 | 2022-02-15 | P Tech, Llc | Methods and devices for utilizing bondable materials |
US11253296B2 (en) | 2006-02-07 | 2022-02-22 | P Tech, Llc | Methods and devices for intracorporeal bonding of implants with thermal energy |
US11259794B2 (en) | 2006-09-29 | 2022-03-01 | Biomet Sports Medicine, Llc | Method for implanting soft tissue |
US11259792B2 (en) | 2006-02-03 | 2022-03-01 | Biomet Sports Medicine, Llc | Method and apparatus for coupling anatomical features |
US20220061832A1 (en) * | 2020-08-31 | 2022-03-03 | Healthium Medtech Limited | Tissue Repair Device and Method to Repair Tissue by Deploying Implants |
US11266430B2 (en) | 2016-11-29 | 2022-03-08 | Cilag Gmbh International | End effector control and calibration |
US20220079576A1 (en) * | 2020-09-15 | 2022-03-17 | Smith & Nephew, Inc. | Joint repair augmentation |
US11278331B2 (en) | 2006-02-07 | 2022-03-22 | P Tech Llc | Method and devices for intracorporeal bonding of implants with thermal energy |
US11304691B2 (en) | 2016-11-13 | 2022-04-19 | Anchora Medical Ltd. | Minimally-invasive tissue suturing device |
US11311326B2 (en) | 2015-02-06 | 2022-04-26 | Cilag Gmbh International | Electrosurgical instrument with rotation and articulation mechanisms |
US11311287B2 (en) | 2006-02-03 | 2022-04-26 | Biomet Sports Medicine, Llc | Method for tissue fixation |
US11311280B2 (en) | 2015-12-15 | 2022-04-26 | Vivasure Medical Limited | Arteriotomy closure apparatus with slotted shoe for advantageous pressure distribution |
US11324527B2 (en) | 2012-11-15 | 2022-05-10 | Cilag Gmbh International | Ultrasonic and electrosurgical devices |
US11337689B2 (en) * | 2020-08-31 | 2022-05-24 | Yoon Ho CHUNG | Benign prostatic hyperplasia treatment device |
US11337747B2 (en) | 2014-04-15 | 2022-05-24 | Cilag Gmbh International | Software algorithms for electrosurgical instruments |
US11357486B2 (en) | 2009-12-30 | 2022-06-14 | Vivasure Medical Limited | Closure system and uses thereof |
US11375994B2 (en) * | 2019-07-12 | 2022-07-05 | Abbot Cardiovascular Systems, Inc. | Methods, systems, and devices for positioning sutures for closing an opening in tissue |
US11382612B1 (en) * | 2021-04-08 | 2022-07-12 | Integrity Orthopaedics, Inc. | Method for creating a tensionable and lockable suture anchor array for anatomical attachment of tissue to bone |
US11399855B2 (en) | 2014-03-27 | 2022-08-02 | Cilag Gmbh International | Electrosurgical devices |
WO2022188376A1 (en) * | 2021-03-12 | 2022-09-15 | 杭州锐健马斯汀医疗器材有限公司 | Implant, implant forming method, and suture instrument |
US11452525B2 (en) | 2019-12-30 | 2022-09-27 | Cilag Gmbh International | Surgical instrument comprising an adjustment system |
US11484401B2 (en) | 2016-02-01 | 2022-11-01 | Medos International Sarl | Tissue augmentation scaffolds for use in soft tissue fixation repair |
US11484358B2 (en) | 2017-09-29 | 2022-11-01 | Cilag Gmbh International | Flexible electrosurgical instrument |
US11490951B2 (en) | 2017-09-29 | 2022-11-08 | Cilag Gmbh International | Saline contact with electrodes |
US11497546B2 (en) | 2017-03-31 | 2022-11-15 | Cilag Gmbh International | Area ratios of patterned coatings on RF electrodes to reduce sticking |
US11589916B2 (en) | 2019-12-30 | 2023-02-28 | Cilag Gmbh International | Electrosurgical instruments with electrodes having variable energy densities |
USD980424S1 (en) | 2020-04-29 | 2023-03-07 | Coloplast A/S | Tissue anchor |
US11660190B2 (en) | 2007-03-13 | 2023-05-30 | Edwards Lifesciences Corporation | Tissue anchors, systems and methods, and devices |
US11660089B2 (en) | 2019-12-30 | 2023-05-30 | Cilag Gmbh International | Surgical instrument comprising a sensing system |
US11684412B2 (en) | 2019-12-30 | 2023-06-27 | Cilag Gmbh International | Surgical instrument with rotatable and articulatable surgical end effector |
US11696776B2 (en) | 2019-12-30 | 2023-07-11 | Cilag Gmbh International | Articulatable surgical instrument |
US11723716B2 (en) | 2019-12-30 | 2023-08-15 | Cilag Gmbh International | Electrosurgical instrument with variable control mechanisms |
US11744575B2 (en) * | 2009-11-09 | 2023-09-05 | Ceterix Orthopaedics, Inc. | Suture passer devices and methods |
US11759251B2 (en) | 2019-12-30 | 2023-09-19 | Cilag Gmbh International | Control program adaptation based on device status and user input |
US11779329B2 (en) | 2019-12-30 | 2023-10-10 | Cilag Gmbh International | Surgical instrument comprising a flex circuit including a sensor system |
US11779387B2 (en) | 2019-12-30 | 2023-10-10 | Cilag Gmbh International | Clamp arm jaw to minimize tissue sticking and improve tissue control |
US11786291B2 (en) | 2019-12-30 | 2023-10-17 | Cilag Gmbh International | Deflectable support of RF energy electrode with respect to opposing ultrasonic blade |
US11812957B2 (en) | 2019-12-30 | 2023-11-14 | Cilag Gmbh International | Surgical instrument comprising a signal interference resolution system |
US11911063B2 (en) | 2019-12-30 | 2024-02-27 | Cilag Gmbh International | Techniques for detecting ultrasonic blade to electrode contact and reducing power to ultrasonic blade |
US11937863B2 (en) | 2019-12-30 | 2024-03-26 | Cilag Gmbh International | Deflectable electrode with variable compression bias along the length of the deflectable electrode |
US11937866B2 (en) | 2019-12-30 | 2024-03-26 | Cilag Gmbh International | Method for an electrosurgical procedure |
US11944366B2 (en) | 2019-12-30 | 2024-04-02 | Cilag Gmbh International | Asymmetric segmented ultrasonic support pad for cooperative engagement with a movable RF electrode |
US11944288B2 (en) | 2020-04-29 | 2024-04-02 | Coloplast A/S | Tissue anchor system including a fixation device and a delivery tool |
US11950797B2 (en) | 2019-12-30 | 2024-04-09 | Cilag Gmbh International | Deflectable electrode with higher distal bias relative to proximal bias |
US11957342B2 (en) | 2021-11-01 | 2024-04-16 | Cilag Gmbh International | Devices, systems, and methods for detecting tissue and foreign objects during a surgical operation |
Families Citing this family (108)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7842048B2 (en) | 2006-08-18 | 2010-11-30 | Abbott Laboratories | Articulating suture device and method |
ES2435094T3 (en) | 2000-05-19 | 2013-12-18 | C.R. Bard, Inc. | Device and method of tissue capture and suturing |
US9005245B2 (en) * | 2002-08-30 | 2015-04-14 | Arthrex, Inc. | Acromioclavicular joint fixation technique |
US7160309B2 (en) | 2002-12-31 | 2007-01-09 | Laveille Kao Voss | Systems for anchoring a medical device in a body lumen |
EP1631201B1 (en) | 2003-05-16 | 2018-11-07 | C.R. Bard, Inc. | Single intubation, multi-stitch endoscopic suturing system |
US7462188B2 (en) | 2003-09-26 | 2008-12-09 | Abbott Laboratories | Device and method for suturing intracardiac defects |
US8267959B2 (en) * | 2003-12-19 | 2012-09-18 | Radi Medical Systems Ab | Technique for securing a suture |
US7449024B2 (en) | 2003-12-23 | 2008-11-11 | Abbott Laboratories | Suturing device with split arm and method of suturing tissue |
WO2005104992A1 (en) * | 2004-04-26 | 2005-11-10 | Bioduct Llc | Stent for avascular meniscal repair and regeneration |
DE102004038823B3 (en) * | 2004-08-04 | 2006-03-30 | Aesculap Ag & Co. Kg | Implant for fixing adjacent bone plates |
US7833244B2 (en) * | 2005-04-20 | 2010-11-16 | Arthroscopic Innovations Llc | Suture fixation device and method for surgical repair |
US20070118152A1 (en) * | 2005-11-21 | 2007-05-24 | Page Thomas C | Surgical suture passer |
US20070156174A1 (en) * | 2006-01-03 | 2007-07-05 | Arthrotek, Inc. | Method and apparatus for repairing a meniscus |
AU2007268046B2 (en) | 2006-05-22 | 2012-08-16 | Covidien Lp | Method and apparatus for meniscal repair |
US8876842B2 (en) | 2006-05-22 | 2014-11-04 | Covidien Lp | Meniscal repair device |
US20080033487A1 (en) * | 2006-08-07 | 2008-02-07 | Bioduct, Llc | Medical device for repair of tissue and method for implantation and fixation |
CA2660117C (en) * | 2006-08-07 | 2012-07-03 | Howmedica Osteonics Corp. | Insertion system for implanting a medical device and surgical methods |
US20080161850A1 (en) * | 2006-12-28 | 2008-07-03 | William Bruce Weisenburgh | Suture anchoring system |
US7951159B2 (en) | 2007-04-04 | 2011-05-31 | Ethicon Endo-Surgery, Inc. | Method for plicating and fastening gastric tissue |
US7815653B2 (en) | 2007-04-04 | 2010-10-19 | Ethicon Endo-Surgery, Inc. | Method for plicating and fastening gastric tissue |
US7722628B2 (en) * | 2007-04-04 | 2010-05-25 | Ethicon Endo-Surgery, Inc. | Device for plicating and fastening gastric tissue |
US7799040B2 (en) | 2007-04-04 | 2010-09-21 | Ethicon Endo-Surgery, Inc. | Device for plicating and fastening gastric tissue |
US7803166B2 (en) | 2007-04-04 | 2010-09-28 | Ethicon Endo-Surgery, Inc. | Method for plicating and fastening gastric tissue |
US7803165B2 (en) | 2007-04-04 | 2010-09-28 | Ethicon Endo-Surgery, Inc. | Device for plicating and fastening gastric tissue |
US9861354B2 (en) | 2011-05-06 | 2018-01-09 | Ceterix Orthopaedics, Inc. | Meniscus repair |
US10441273B2 (en) | 2007-07-03 | 2019-10-15 | Ceterix Orthopaedics, Inc. | Pre-tied surgical knots for use with suture passers |
US8465505B2 (en) | 2011-05-06 | 2013-06-18 | Ceterix Orthopaedics, Inc. | Suture passer devices and methods |
US8162961B2 (en) * | 2007-07-23 | 2012-04-24 | Zimmer Orthobiologies, Inc. | Medical devices and methods for cutting and suturing biological tissue |
US7731732B2 (en) * | 2007-08-31 | 2010-06-08 | Ken Christopher G M | Closure medical device |
US20090082806A1 (en) * | 2007-09-24 | 2009-03-26 | Hs West Investments, Llc | Meniscal repair system |
EP2098172B1 (en) * | 2008-03-04 | 2017-02-22 | Arthrex, Inc. | System for meniscal repair using suture implant cinch construct |
US8105343B2 (en) * | 2008-06-30 | 2012-01-31 | Arthrocare Corporation | Independent suture tensioning and snaring apparatus |
US20100121355A1 (en) | 2008-10-24 | 2010-05-13 | The Foundry, Llc | Methods and devices for suture anchor delivery |
CN102292032A (en) * | 2008-11-26 | 2011-12-21 | 史密夫和内修有限公司 | Tissue repair device |
WO2010111176A1 (en) | 2009-03-23 | 2010-09-30 | Linvatec Corporation | Suture passing apparatus and method |
EP2429410B1 (en) | 2009-05-12 | 2017-07-12 | The Foundry, LLC | Knotless suture anchor |
US20100292731A1 (en) | 2009-05-12 | 2010-11-18 | Foundry Newco Xl, Inc. | Methods and devices to treat diseased or injured musculoskeletal tissue |
US8828053B2 (en) | 2009-07-24 | 2014-09-09 | Depuy Mitek, Llc | Methods and devices for repairing and anchoring damaged tissue |
US8814903B2 (en) | 2009-07-24 | 2014-08-26 | Depuy Mitek, Llc | Methods and devices for repairing meniscal tissue |
US20110022064A1 (en) * | 2009-07-27 | 2011-01-27 | Tyco Healthcare Group Lp | Access apparatus including hinged suture traps |
US9011487B2 (en) * | 2009-08-27 | 2015-04-21 | Ethicon, Inc. | Barbed sutures having pledget stoppers and methods therefor |
US9011454B2 (en) * | 2009-11-09 | 2015-04-21 | Ceterix Orthopaedics, Inc. | Suture passer with radiused upper jaw |
US9848868B2 (en) | 2011-01-10 | 2017-12-26 | Ceterix Orthopaedics, Inc. | Suture methods for forming locking loops stitches |
WO2011057394A1 (en) | 2009-11-12 | 2011-05-19 | Anchor Orthopedics Xt, Inc. | Devices and methods for treating tissue defects |
US9855031B2 (en) | 2010-04-13 | 2018-01-02 | Neosurgical Limited | Suture delivery system |
GB2486497B (en) | 2010-12-17 | 2013-06-19 | Neosurgical Ltd | Laparoscopic trocar system |
US9743919B2 (en) | 2010-04-27 | 2017-08-29 | DePuy Synthes Products, Inc. | Stitch lock for attaching two or more structures |
US9724080B2 (en) | 2010-04-27 | 2017-08-08 | DePuy Synthes Products, Inc. | Insertion instrument for anchor assembly |
AU2011245417B2 (en) | 2010-04-27 | 2015-04-09 | Synthes Gmbh | Anchor assembly including expandable anchor |
US9451938B2 (en) | 2010-04-27 | 2016-09-27 | DePuy Synthes Products, Inc. | Insertion instrument for anchor assembly |
US9370353B2 (en) | 2010-09-01 | 2016-06-21 | Abbott Cardiovascular Systems, Inc. | Suturing devices and methods |
US9119893B2 (en) | 2010-11-04 | 2015-09-01 | Linvatec Corporation | Method and apparatus for securing an object to bone, including the provision and use of a novel suture assembly for securing an object to bone |
US9307977B2 (en) | 2010-11-04 | 2016-04-12 | Conmed Corporation | Method and apparatus for securing an object to bone, including the provision and use of a novel suture assembly for securing suture to bone |
US9307978B2 (en) | 2010-11-04 | 2016-04-12 | Linvatec Corporation | Method and apparatus for securing an object to bone, including the provision and use of a novel suture assembly for securing an object to bone |
US9913638B2 (en) | 2011-01-10 | 2018-03-13 | Ceterix Orthopaedics, Inc. | Transosteal anchoring methods for tissue repair |
US9421132B2 (en) | 2011-02-04 | 2016-08-23 | University Of Massachusetts | Negative pressure wound closure device |
EP3932327A1 (en) | 2011-02-04 | 2022-01-05 | University Of Massachusetts | Negative pressure wound closure device |
US20120253388A1 (en) * | 2011-03-29 | 2012-10-04 | Tyco Healthcare Group Lp | Anchor Member For Looped Sutures |
US20120290002A1 (en) * | 2011-05-12 | 2012-11-15 | Smith & Nephew, Inc. | Tissue graft anchoring |
WO2012158617A2 (en) * | 2011-05-13 | 2012-11-22 | Suspension Orthopaedic Solutions, Inc. | Adjustable suture lock loop |
US8926661B2 (en) * | 2011-06-02 | 2015-01-06 | Smith & Nephew, Inc. | Surgical fastening |
US10524778B2 (en) | 2011-09-28 | 2020-01-07 | Ceterix Orthopaedics | Suture passers adapted for use in constrained regions |
EP2838438A1 (en) * | 2012-03-09 | 2015-02-25 | Keith A. Knoell | Lattice stitch surgical tension limiting device |
US8858573B2 (en) | 2012-04-10 | 2014-10-14 | Abbott Cardiovascular Systems, Inc. | Apparatus and method for suturing body lumens |
MX2014014265A (en) | 2012-05-22 | 2015-06-23 | Smith & Nephew | Wound closure device. |
WO2013175310A2 (en) | 2012-05-22 | 2013-11-28 | Smith & Nephew Plc | Apparatuses and methods for wound therapy |
MX2014014325A (en) | 2012-05-24 | 2015-08-06 | Smith & Nephew Inc | Devices and methods for treating and closing wounds with negative pressure. |
US9241707B2 (en) | 2012-05-31 | 2016-01-26 | Abbott Cardiovascular Systems, Inc. | Systems, methods, and devices for closing holes in body lumens |
MX369689B (en) | 2012-07-16 | 2019-11-19 | Smith & Nephew Inc | Negative pressure wound closure device. |
US9427228B2 (en) | 2012-11-09 | 2016-08-30 | Karl Storz Gmbh & Co. Kg | Suture cartridge for meniscal repair |
EP2740414B1 (en) | 2012-12-06 | 2018-02-07 | Karl Storz SE & Co. KG | Suture anchor delivery device |
EP2740415B1 (en) | 2012-12-06 | 2017-02-08 | Karl Storz GmbH & Co. KG | Suture holding system |
MX369065B (en) | 2013-03-13 | 2019-10-28 | Smith & Nephew Inc | Negative pressure wound closure device and systems and methods of use in treating wounds with negative pressure. |
AU2014229749B2 (en) | 2013-03-14 | 2018-09-20 | Smith & Nephew Plc | Compressible wound fillers and systems and methods of use in treating wounds with negative pressure |
JP2016513566A (en) | 2013-03-15 | 2016-05-16 | スミス アンド ネフュー インコーポレーテッドSmith & Nephew,Inc. | Surgical fixation device |
US9247935B2 (en) | 2013-09-23 | 2016-02-02 | Ceterix Orthopaedics, Inc. | Arthroscopic knot pusher and suture cutter |
EP3060181B1 (en) | 2013-10-21 | 2021-11-03 | Smith & Nephew, Inc. | Negative pressure wound closure device |
WO2015095133A1 (en) | 2013-12-16 | 2015-06-25 | Ceterix Orthopaedics, Inc. | Automatically reloading suture passer devices having pre-tied knots and methods |
CA2937399C (en) | 2014-01-21 | 2023-01-24 | Smith & Nephew Plc | Collapsible dressing for negative pressure wound treatment |
CN105250001B (en) | 2014-04-08 | 2019-07-12 | 赛特里克斯整形公司 | Suitable for suture passer used in confined area |
US10568616B2 (en) | 2014-12-17 | 2020-02-25 | Howmedica Osteonics Corp. | Instruments and methods of soft tissue fixation |
JP2018519864A (en) | 2015-04-29 | 2018-07-26 | スミス アンド ネフュー インコーポレイテッド | Negative pressure wound closure device |
US9937032B2 (en) | 2015-06-04 | 2018-04-10 | Medos International Sarl | Tissue fixation device |
US10226245B2 (en) | 2015-07-21 | 2019-03-12 | Ceterix Orthopaedics, Inc. | Automatically reloading suture passer devices that prevent entanglement |
US11357499B2 (en) | 2015-08-18 | 2022-06-14 | Lsi Solutions, Inc. | Apparatus for mitral valve repair and methods thereof |
US10405853B2 (en) | 2015-10-02 | 2019-09-10 | Ceterix Orthpaedics, Inc. | Knot tying accessory |
US10814049B2 (en) | 2015-12-15 | 2020-10-27 | University Of Massachusetts | Negative pressure wound closure devices and methods |
US10575991B2 (en) | 2015-12-15 | 2020-03-03 | University Of Massachusetts | Negative pressure wound closure devices and methods |
US10085830B2 (en) * | 2016-05-13 | 2018-10-02 | Medos International Sarl | Device, system, and method for delivery of a tissue fixation device |
US10426449B2 (en) | 2017-02-16 | 2019-10-01 | Abbott Cardiovascular Systems, Inc. | Articulating suturing device with improved actuation and alignment mechanisms |
US10758224B2 (en) | 2017-03-27 | 2020-09-01 | Trimed, Incorporated | System and method controlling a relationship between first and second bodies on a person |
US10675015B2 (en) * | 2017-07-12 | 2020-06-09 | Ethicon, Inc. | Systems, devices and methods for delivering transfascial suture implants for securing surgical mesh to tissue |
US20200383679A1 (en) * | 2017-11-27 | 2020-12-10 | T.A.G. Medical Devices - Agriculture Cooperative Ltd. | Multiple anchor delivery system and method |
USD902405S1 (en) | 2018-02-22 | 2020-11-17 | Stryker Corporation | Self-punching bone anchor inserter |
WO2020118087A1 (en) * | 2018-12-05 | 2020-06-11 | Paragon 28, Inc. | Soft tissue implant systems, instruments and related methods |
WO2020124038A1 (en) | 2018-12-13 | 2020-06-18 | University Of Massachusetts | Negative pressure wound closure devices and methods |
US11395687B2 (en) | 2019-03-01 | 2022-07-26 | DePuy Synthes Products, Inc. | Insertion tool for flip anchor cable system insertion |
WO2020256922A1 (en) | 2019-06-18 | 2020-12-24 | Smith & Nephew, Inc. | Bending tools and methods of use thereof |
WO2021150706A1 (en) * | 2020-01-21 | 2021-07-29 | Children's Medical Center Corporation | Tissue fastening |
CN115379876A (en) | 2020-02-11 | 2022-11-22 | 恩博迪股份有限公司 | Surgical cannula with removable pressure seal |
EP4103069A1 (en) | 2020-02-11 | 2022-12-21 | Embody Inc. | Surgical anchoring device, deployment device, and method of use |
EP4103106A4 (en) | 2020-02-11 | 2024-03-13 | Embody Inc | Implant delivery device |
US11969166B2 (en) * | 2020-10-07 | 2024-04-30 | Smith & Nephew, Inc. | Hip capsule closure |
US20220151603A1 (en) * | 2020-11-13 | 2022-05-19 | Siesta Medical, Inc. | Anchoring systems and methods |
US11382611B1 (en) | 2021-04-08 | 2022-07-12 | Integrity Orthopaedics, Inc. | Knotless micro-suture anchors and anchor arrays for anatomical attachment of soft tissue to bone |
US11375995B1 (en) | 2021-04-08 | 2022-07-05 | Integrity Orthopaedics, Inc. | Locking suture construct for tensioned suture to suture stitches in anchor arrays for attaching soft tissue to bone |
US11389290B1 (en) | 2021-04-08 | 2022-07-19 | Integrity Orthopaedics, Inc. | Delivery device for implanting knotless micro-suture anchors and anchor arrays for attachment of soft tissue to bone |
US11382613B1 (en) | 2021-04-08 | 2022-07-12 | Integrity Orthopaedics, Inc. | Methods for transtendinous implantation of knotless micro suture anchors and anchor arrays |
Family Cites Families (293)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US331626A (en) | 1885-12-01 | Eoeseshoe swaging machine | ||
US233475A (en) | 1880-10-19 | l vandermark | ||
US261501A (en) | 1882-07-18 | Bag and sail tie | ||
FR27316E (en) | 1922-10-12 | 1924-06-06 | Metallurg Electr | Selective transformer |
US1635066A (en) | 1927-02-08 | 1927-07-05 | Walter A Wells | Surgical instrument |
US2479464A (en) | 1946-11-04 | 1949-08-16 | Harry G Bliss | Surgical needle |
US2610631A (en) | 1949-11-02 | 1952-09-16 | David J Calicchio | Ligator |
US2881762A (en) | 1955-02-09 | 1959-04-14 | Robert J Lowrie | Surgical staple and stapler |
US2880728A (en) | 1958-02-03 | 1959-04-07 | Clyde S Rights | Ligature inserter |
NL137173C (en) | 1965-10-08 | 1900-01-01 | ||
US3470875A (en) | 1966-10-06 | 1969-10-07 | Alfred A Johnson | Surgical clamping and suturing instrument |
US3618447A (en) | 1969-09-15 | 1971-11-09 | Phillips Petroleum Co | Deterioration fasteners |
US3664345A (en) | 1970-07-06 | 1972-05-23 | Clyde Harwell Dabbs | Surgical buttons |
US3716058A (en) | 1970-07-17 | 1973-02-13 | Atlanta Res Inst | Barbed suture |
US3757629A (en) | 1971-05-10 | 1973-09-11 | R Schneider | Resilient plastic staple |
US3871379A (en) | 1971-08-26 | 1975-03-18 | Henry C N Clarke | Laparoscopy instruments and method for suturing and ligation |
US3840017A (en) | 1971-10-29 | 1974-10-08 | A Violante | Surgical instrument |
US3752519A (en) | 1971-12-02 | 1973-08-14 | H Kimball | Mechanical latch |
US3752516A (en) | 1971-12-07 | 1973-08-14 | P Mumma | Knot tying jig |
US3985138A (en) | 1972-08-25 | 1976-10-12 | Jarvik Robert K | Preformed ligatures for bleeders and methods of applying such ligatures |
US3867944A (en) | 1972-10-27 | 1975-02-25 | Wood Ernest C | Hemostatic clip and applicator therefor |
US3842824A (en) | 1973-03-19 | 1974-10-22 | A Neufeld | Notched surgical pin and breaking tool therefor |
US3825010A (en) | 1973-04-23 | 1974-07-23 | Donald B Mc | Surgical apparatus for closing wounds |
US3842840A (en) | 1973-05-07 | 1974-10-22 | E Schweizer | Suture applicator |
US3910281A (en) | 1973-10-09 | 1975-10-07 | Bio Medicus Inc | Suture anchor |
US3977050A (en) | 1974-04-19 | 1976-08-31 | Monarch Marking Systems, Inc. | Fastener assembly |
HU169185B (en) | 1974-06-05 | 1976-10-28 | ||
US3976079A (en) | 1974-08-01 | 1976-08-24 | Samuels Peter B | Securing devices for sutures |
US3946740A (en) | 1974-10-15 | 1976-03-30 | Bassett John W | Suturing device |
US4006747A (en) | 1975-04-23 | 1977-02-08 | Ethicon, Inc. | Surgical method |
US4186514A (en) | 1975-09-29 | 1980-02-05 | Ramiro Oquita | Slip-knot pinata |
US4160453A (en) | 1975-12-05 | 1979-07-10 | Hairegenics, Inc. | Apparatus for implanting hair |
GB1545731A (en) * | 1976-09-07 | 1979-05-16 | Vnii Ispytatel Med Tech | Surgical apparatus |
US4105349A (en) * | 1976-10-18 | 1978-08-08 | R B Toy Development Co. | Mechanism for forming a loop in a rope or the like |
US4141087A (en) * | 1977-01-19 | 1979-02-27 | Ethicon, Inc. | Isomorphic copolyoxalates and sutures thereof |
US4144876A (en) * | 1977-12-20 | 1979-03-20 | Deleo David B | Hair implanting method |
FR2422386A1 (en) | 1978-04-13 | 1979-11-09 | Christian Buscayret | Device for fastening suture into tissue - has rectangular body with two perforations accommodating suture and two protuberances engaging tissue |
JPS5921776Y2 (en) | 1978-06-08 | 1984-06-28 | オリンパス光学工業株式会社 | suture needle |
JPS5921775Y2 (en) | 1978-05-11 | 1984-06-28 | オリンパス光学工業株式会社 | suture needle |
US4235238A (en) | 1978-05-11 | 1980-11-25 | Olympus Optical Co., Ltd. | Apparatus for suturing coeliac tissues |
JPS6024356Y2 (en) | 1978-05-11 | 1985-07-20 | オリンパス光学工業株式会社 | Suture for intrabody tissue |
JPS5835219Y2 (en) | 1978-06-01 | 1983-08-08 | オリンパス光学工業株式会社 | Body cavity tissue suturing device |
JPS5542626A (en) | 1978-09-20 | 1980-03-26 | Olympus Optical Co | Blocking device of coelom inside tubular portion |
US4185514A (en) * | 1978-10-02 | 1980-01-29 | Edwards E David | Adapter for motor-speed reducer sets |
US4505274A (en) | 1980-10-17 | 1985-03-19 | Propper Manufacturing Co., Inc. | Suture clip |
US4809695A (en) | 1981-10-21 | 1989-03-07 | Owen M. Gwathmey | Suturing assembly and method |
US4509518A (en) | 1982-02-17 | 1985-04-09 | United States Surgical Corporation | Apparatus for applying surgical clips |
US5417691A (en) | 1982-05-20 | 1995-05-23 | Hayhurst; John O. | Apparatus and method for manipulating and anchoring tissue |
US4741330A (en) | 1983-05-19 | 1988-05-03 | Hayhurst John O | Method and apparatus for anchoring and manipulating cartilage |
US5601557A (en) | 1982-05-20 | 1997-02-11 | Hayhurst; John O. | Anchoring and manipulating tissue |
US6656182B1 (en) | 1982-05-20 | 2003-12-02 | John O. Hayhurst | Tissue manipulation |
US4823794A (en) | 1982-07-12 | 1989-04-25 | Pierce William S | Surgical pledget |
US4438253A (en) | 1982-11-12 | 1984-03-20 | American Cyanamid Company | Poly(glycolic acid)/poly(alkylene glycol) block copolymers and method of manufacturing the same |
US4493323A (en) | 1982-12-13 | 1985-01-15 | University Of Iowa Research Foundation | Suturing device and method for using same |
US4595007A (en) | 1983-03-14 | 1986-06-17 | Ethicon, Inc. | Split ring type tissue fastener |
US4570623A (en) | 1983-06-02 | 1986-02-18 | Pfizer Hospital Products Group Inc. | Arched bridge staple |
US4531522A (en) | 1983-06-20 | 1985-07-30 | Ethicon, Inc. | Two-piece tissue fastener with locking top and method for applying same |
US4534350A (en) | 1983-06-20 | 1985-08-13 | Ethicon, Inc. | Two-piece tissue fastener with compressible leg staple and retaining receiver |
US4596249A (en) | 1983-07-26 | 1986-06-24 | Freda Vincent J | Implement for setting sutures |
US4602635A (en) | 1983-11-14 | 1986-07-29 | Mulhollan James S | Remote surgical knot tier and method of use |
US4873976A (en) | 1984-02-28 | 1989-10-17 | Schreiber Saul N | Surgical fasteners and method |
US4635637A (en) | 1984-03-29 | 1987-01-13 | Schreiber Saul N | Surgical suture |
DE3413744C2 (en) | 1984-04-12 | 1986-08-28 | Richard Wolf Gmbh, 7134 Knittlingen | Applicator for knotting sewing threads |
US4741336A (en) | 1984-07-16 | 1988-05-03 | Ethicon, Inc. | Shaped staples and slotted receivers (case VII) |
US4616650A (en) | 1984-07-27 | 1986-10-14 | United States Surgical Corporation | Apparatus for applying surgical clips |
DE3445738A1 (en) | 1984-12-14 | 1986-06-19 | Draenert Klaus | IMPLANT FOR BONE REINFORCEMENT AND ANCHORING OF BONE SCREWS, IMPLANTS OR IMPLANT PARTS |
US4750492A (en) | 1985-02-27 | 1988-06-14 | Richards Medical Company | Absorbable suture apparatus, method and installer |
US4636121A (en) | 1985-04-22 | 1987-01-13 | Miller Lillias S | Holding screw |
US4781190A (en) | 1985-06-18 | 1988-11-01 | Lee Wilson K C | Method of arthroscopic repair of a limb joint |
US4662068A (en) | 1985-11-14 | 1987-05-05 | Eli Polonsky | Suture fusing and cutting apparatus |
US4705040A (en) | 1985-11-18 | 1987-11-10 | Medi-Tech, Incorporated | Percutaneous fixation of hollow organs |
US4895148A (en) | 1986-05-20 | 1990-01-23 | Concept, Inc. | Method of joining torn parts of bodily tissue in vivo with a biodegradable tack member |
US4884572A (en) | 1986-05-20 | 1989-12-05 | Concept, Inc. | Tack and applicator for treating torn bodily material in vivo |
US4723540A (en) | 1986-07-15 | 1988-02-09 | Gilmer Jr Raymond E | Apparatus and method for exerting and maintaining a force between two bone members |
GB8620560D0 (en) | 1986-08-23 | 1986-10-01 | Femcare Ltd | Applicator |
US4724839A (en) | 1986-09-18 | 1988-02-16 | Ethicon, Inc. | Surgical fastening systems made from polymeric materials |
GB8622563D0 (en) | 1986-09-19 | 1986-10-22 | Amis A A | Artificial ligaments |
US4760848A (en) | 1986-11-03 | 1988-08-02 | Hasson Harrith M | Rotational surgical instrument |
US4841960A (en) | 1987-02-10 | 1989-06-27 | Garner Eric T | Method and apparatus for interosseous bone fixation |
US4719917A (en) | 1987-02-17 | 1988-01-19 | Minnesota Mining And Manufacturing Company | Surgical staple |
US4846793A (en) | 1987-03-18 | 1989-07-11 | Endocon, Inc. | Injector for implanting multiple pellet medicaments |
US4994028A (en) * | 1987-03-18 | 1991-02-19 | Endocon, Inc. | Injector for inplanting multiple pellet medicaments |
US5437680A (en) | 1987-05-14 | 1995-08-01 | Yoon; Inbae | Suturing method, apparatus and system for use in endoscopic procedures |
US4898156A (en) | 1987-05-18 | 1990-02-06 | Mitek Surgical Products, Inc. | Suture anchor |
US5261914A (en) | 1987-09-02 | 1993-11-16 | Russell Warren | Surgical fastener |
US4890615B1 (en) | 1987-11-05 | 1993-11-16 | Linvatec Corporation | Arthroscopic suturing instrument |
US4887601A (en) | 1987-11-06 | 1989-12-19 | Ophthalmic Ventures Limited Partnership | Adjustable surgical staple and method of using the same |
US4899743A (en) * | 1987-12-15 | 1990-02-13 | Mitek Surgical Products, Inc. | Suture anchor installation tool |
US4917699A (en) * | 1988-05-16 | 1990-04-17 | Zimmer, Inc. | Prosthetic ligament |
US5154189A (en) | 1988-06-03 | 1992-10-13 | Oberlander Michael A | Method for repairing a torn meniscus |
US5484437A (en) | 1988-06-13 | 1996-01-16 | Michelson; Gary K. | Apparatus and method of inserting spinal implants |
US4983176A (en) | 1989-03-06 | 1991-01-08 | University Of New Mexico | Deformable plastic surgical clip |
US5053047A (en) | 1989-05-16 | 1991-10-01 | Inbae Yoon | Suture devices particularly useful in endoscopic surgery and methods of suturing |
US5234426A (en) | 1989-06-15 | 1993-08-10 | Research Corporation Technologies, Inc. | Helical-tipped lesion localization needle device and method of using the same |
US5129906A (en) | 1989-09-08 | 1992-07-14 | Linvatec Corporation | Bioabsorbable tack for joining bodily tissue and in vivo method and apparatus for deploying same |
US5290558A (en) | 1989-09-21 | 1994-03-01 | Osteotech, Inc. | Flowable demineralized bone powder composition and its use in bone repair |
US5059201A (en) | 1989-11-03 | 1991-10-22 | Asnis Stanley E | Suture threading, stitching and wrapping device for use in open and closed surgical procedures |
US5123913A (en) | 1989-11-27 | 1992-06-23 | Wilk Peter J | Suture device |
US4950285A (en) | 1989-11-27 | 1990-08-21 | Wilk Peter J | Suture device |
US5100415A (en) * | 1990-01-08 | 1992-03-31 | Hayhurst John O | Knotting instrument |
US4961741A (en) | 1990-01-08 | 1990-10-09 | Hayhurst John O | Suture knotting instrument |
US5084058A (en) | 1990-04-25 | 1992-01-28 | Mitek Surgical Products, Inc. | Suture rundown tool and cutter system |
US5087263A (en) | 1990-04-25 | 1992-02-11 | Mitek Surgical Products, Inc. | Suture throw holder and rundown system |
US5078731A (en) * | 1990-06-05 | 1992-01-07 | Hayhurst John O | Suture clip |
US5102421A (en) * | 1990-06-14 | 1992-04-07 | Wm. E. Anpach, III | Suture anchor and method of forming |
US5318577A (en) | 1990-06-26 | 1994-06-07 | Mitek Surgical Products, Inc. | Suture threading device |
US5236445A (en) | 1990-07-02 | 1993-08-17 | American Cyanamid Company | Expandable bone anchor and method of anchoring a suture to a bone |
US5037422A (en) | 1990-07-02 | 1991-08-06 | Acufex Microsurgical, Inc. | Bone anchor and method of anchoring a suture to a bone |
US5224946A (en) | 1990-07-02 | 1993-07-06 | American Cyanamid Company | Bone anchor and method of anchoring a suture to a bone |
US5269809A (en) | 1990-07-02 | 1993-12-14 | American Cyanamid Company | Locking mechanism for use with a slotted suture anchor |
US5041129A (en) | 1990-07-02 | 1991-08-20 | Acufex Microsurgical, Inc. | Slotted suture anchor and method of anchoring a suture |
US5258016A (en) | 1990-07-13 | 1993-11-02 | American Cyanamid Company | Suture anchor and driver assembly |
USD331626S (en) | 1990-07-13 | 1992-12-08 | American Cyanamid Company | Bone anchor |
GB9020379D0 (en) | 1990-09-18 | 1990-10-31 | Femcare Ltd | Suture apparatus |
US5725529A (en) * | 1990-09-25 | 1998-03-10 | Innovasive Devices, Inc. | Bone fastener |
DE69130681T2 (en) | 1990-09-25 | 1999-06-10 | Innovasive Devices Inc | BONE FIXING DEVICE |
US5203787A (en) * | 1990-11-19 | 1993-04-20 | Biomet, Inc. | Suture retaining arrangement |
US5149329A (en) | 1990-12-12 | 1992-09-22 | Wayne State University | Surgical suture carrier and method for urinary bladder neck suspension |
US5211650A (en) | 1991-01-07 | 1993-05-18 | Laparomed Corporation | Dual function suturing device and method |
US5207753A (en) * | 1991-02-18 | 1993-05-04 | Kannivelu Badrinath | Bone fracture repair apparatus and method |
US5720753A (en) * | 1991-03-22 | 1998-02-24 | United States Surgical Corporation | Orthopedic fastener |
US5217470A (en) | 1991-04-29 | 1993-06-08 | Weston Peter V | Apparatuses and methods for formation and use of a slipknot as a surgical suture knot |
US5258015A (en) | 1991-05-03 | 1993-11-02 | American Cyanamid Company | Locking filament caps |
US5141520A (en) | 1991-10-29 | 1992-08-25 | Marlowe Goble E | Harpoon suture anchor |
US5178629A (en) | 1992-03-03 | 1993-01-12 | Ethicon, Inc. | Method of forming a suture knot |
US5336231A (en) | 1992-05-01 | 1994-08-09 | Adair Edwin Lloyd | Parallel channel fixation, repair and ligation suture device |
US5250055A (en) | 1992-06-08 | 1993-10-05 | Orthopedic Systems Inc. | Method and apparatus for tying suture to bone |
US5281236A (en) | 1992-06-23 | 1994-01-25 | Boston Scientific Corporation | Method and device for intracorporeal knot tying |
US5279539A (en) * | 1992-08-17 | 1994-01-18 | Ethicon, Inc. | Drawstring surgical pouch and method of use for preventing ovarian adhesions |
US5364408A (en) | 1992-09-04 | 1994-11-15 | Laurus Medical Corporation | Endoscopic suture system |
US5342369A (en) | 1992-09-11 | 1994-08-30 | The Board Of Regents Of The University Of Washington | System for repair of bankart lesions |
CA2437777C (en) | 1992-09-21 | 2006-11-28 | United States Surgical Corporation | Device for applying a meniscal staple |
SE510158C2 (en) * | 1992-10-29 | 1999-04-26 | Medevelop Ab | Anchorage elements for supporting prostheses and the use of such anchorage elements for fixing dentures |
IL103737A (en) * | 1992-11-13 | 1997-02-18 | Technion Res & Dev Foundation | Stapler device particularly useful in medical suturing |
US5972000A (en) | 1992-11-13 | 1999-10-26 | Influence Medical Technologies, Ltd. | Non-linear anchor inserter device and bone anchors |
US5282809A (en) | 1992-11-16 | 1994-02-01 | Ethicon, Inc. | Endoscopic suturing device |
ES2111689T3 (en) | 1992-11-17 | 1998-03-16 | Smith & Nephew Inc | LOCKING DEVICE FOR THE IMMOBILIZATION OF A THREAD OF SUTURE. |
US5354299A (en) | 1992-12-07 | 1994-10-11 | Linvatec Corporation | Method of revising a screw in a tunnel |
US5320633A (en) | 1992-12-10 | 1994-06-14 | William C. Allen | Method and system for repairing a tear in the meniscus |
US5467786A (en) | 1992-12-10 | 1995-11-21 | William C. Allen | Method for repairing tears and incisions in soft tissue |
AU5987494A (en) | 1993-01-07 | 1994-08-15 | Hayhurst, John O. | Clip for suture |
US5522820A (en) | 1993-01-15 | 1996-06-04 | Arthrotech | Method and apparatus for suturing tissue |
US5336229A (en) | 1993-02-09 | 1994-08-09 | Laparomed Corporation | Dual ligating and dividing apparatus |
US5441502A (en) | 1993-02-17 | 1995-08-15 | Mitek Surgical Products, Inc. | System and method for re-attaching soft tissue to bone |
US5380334A (en) * | 1993-02-17 | 1995-01-10 | Smith & Nephew Dyonics, Inc. | Soft tissue anchors and systems for implantation |
US5403348A (en) * | 1993-05-14 | 1995-04-04 | Bonutti; Peter M. | Suture anchor |
US5458608A (en) | 1993-06-03 | 1995-10-17 | Surgin Surgical Instrumentation Inc. | Laparoscopic instruments and methods |
US5522844A (en) | 1993-06-22 | 1996-06-04 | Johnson; Lanny L. | Suture anchor, suture anchor installation device and method for attaching a suture to a bone |
US5500000A (en) * | 1993-07-01 | 1996-03-19 | United States Surgical Corporation | Soft tissue repair system and method |
US5562687A (en) | 1993-07-12 | 1996-10-08 | Mitek Surgical Products, Inc. | Surgical repair kit and its method of use |
US5496331A (en) | 1993-07-28 | 1996-03-05 | Terumo Kabushiki Kaisha | Knot-forming instrument and method of forming knots |
US5609597A (en) * | 1993-12-09 | 1997-03-11 | Lehrer; Theodor | Apparatus and method of extracorporeally applying and locking laparoscopic suture and loop ligatures |
US5527342A (en) | 1993-12-14 | 1996-06-18 | Pietrzak; William S. | Method and apparatus for securing soft tissues, tendons and ligaments to bone |
US5417692A (en) * | 1994-01-04 | 1995-05-23 | Goble; E. Marlowe | Bone fixation and fusion system |
US5520921A (en) * | 1994-02-01 | 1996-05-28 | Wellesley Research Associates, Inc. | Periodontal packing device |
DE9403161U1 (en) * | 1994-02-25 | 1994-04-21 | Sueddeutsche Feinmechanik | Cannula |
US5545178A (en) | 1994-04-29 | 1996-08-13 | Kensey Nash Corporation | System for closing a percutaneous puncture formed by a trocar to prevent tissue at the puncture from herniating |
US5641256A (en) | 1994-06-09 | 1997-06-24 | Npc, Inc. | Anchoring device for a threaded member |
US5490750A (en) | 1994-06-09 | 1996-02-13 | Gundy; William P. | Anchoring device for a threaded member |
US5593424A (en) * | 1994-08-10 | 1997-01-14 | Segmed, Inc. | Apparatus and method for reducing and stabilizing the circumference of a vascular structure |
US5458081A (en) | 1994-09-12 | 1995-10-17 | Reichert; Susan A. | Adjustable bookmark |
US5730744A (en) * | 1994-09-27 | 1998-03-24 | Justin; Daniel F. | Soft tissue screw, delivery device, and method |
US5520696A (en) * | 1994-09-27 | 1996-05-28 | Mitek Surgical Products, Inc. | Bone anchor installation tool |
US5562684A (en) | 1994-10-11 | 1996-10-08 | Ethicon, Inc. | Surgical knot pusher device and improved method of forming knots |
US5643321A (en) | 1994-11-10 | 1997-07-01 | Innovasive Devices | Suture anchor assembly and methods |
JP3798838B2 (en) * | 1995-01-20 | 2006-07-19 | オリンパス株式会社 | Ligation device |
US5607432A (en) * | 1995-01-23 | 1997-03-04 | Linvatec Corporation | Threaded suture anchor retriever |
US5573286A (en) | 1995-03-15 | 1996-11-12 | Rogozinski; Chaim | Knot |
FR2731610B1 (en) | 1995-03-16 | 1997-06-20 | Amp Dev | ANCHOR FOR INSERTION INTO A BONE CAVITY. |
JP3689146B2 (en) | 1995-05-30 | 2005-08-31 | ペンタックス株式会社 | Elements for screw fixation to bone |
US5569306A (en) | 1995-06-06 | 1996-10-29 | Thal; Raymond | Knotless suture anchor assembly |
US5658299A (en) | 1995-07-20 | 1997-08-19 | Applied Medical Resources | Surgical ligating device and method for using same |
US5843084A (en) | 1995-11-17 | 1998-12-01 | Innovasive Devices, Inc. | Surgical fastening system and method for using the same |
US5702422A (en) | 1995-12-06 | 1997-12-30 | Stone; Kevin R. | Anterior cruciate ligament repair method |
US5725556A (en) | 1995-12-15 | 1998-03-10 | M & R Medical, Inc. | Suture locking apparatus |
US5662658A (en) * | 1996-01-19 | 1997-09-02 | Mitek Surgical Products, Inc. | Bone anchor inserter, method for loading same, method for holding and delivering a bone anchor, and method for inserting a bone anchor in a bone |
US5702462A (en) | 1996-01-24 | 1997-12-30 | Oberlander; Michael | Method of meniscal repair |
US5690678A (en) | 1996-04-30 | 1997-11-25 | Johnson; Lanny L. | Arrangement for anchoring suture to bone |
US5893856A (en) * | 1996-06-12 | 1999-04-13 | Mitek Surgical Products, Inc. | Apparatus and method for binding a first layer of material to a second layer of material |
US5782862A (en) | 1996-07-01 | 1998-07-21 | Bonutti; Peter M. | Suture anchor inserter assembly and method |
US5810848A (en) * | 1996-08-21 | 1998-09-22 | Hayhurst; John O. | Suturing system |
WO1998011839A1 (en) | 1996-09-20 | 1998-03-26 | Medicinelodge, Inc. | Adjustable length strap and footing for ligament mounting and method for its use |
US6152936A (en) * | 1996-09-23 | 2000-11-28 | Esd Medical, Llc | Surgical loop delivery device |
GB9620046D0 (en) * | 1996-09-26 | 1996-11-13 | Neoligaments | Attachment device for use in the implantation of prosthetic ligament |
CA2217435C (en) | 1996-10-04 | 2006-08-29 | United States Surgical Corporation | Tissue fastener implantation apparatus and method |
US5948002A (en) | 1996-11-15 | 1999-09-07 | Bonutti; Peter M. | Apparatus and method for use in positioning a suture anchor |
AU5407598A (en) | 1996-11-15 | 1998-06-10 | Medisolve Ltd. | Bone implant |
CA2224366C (en) | 1996-12-11 | 2006-10-31 | Ethicon, Inc. | Meniscal repair device |
US5843087A (en) | 1997-01-30 | 1998-12-01 | Ethicon, Inc. | Suture anchor installation tool |
US5709708A (en) * | 1997-01-31 | 1998-01-20 | Thal; Raymond | Captured-loop knotless suture anchor assembly |
US5713904A (en) | 1997-02-12 | 1998-02-03 | Third Millennium Engineering, Llc | Selectively expandable sacral fixation screw-sleeve device |
FR2760185B1 (en) | 1997-02-28 | 1999-05-14 | Laurent Fumex | SURGICAL BONE AND ANCILLARY ANCHORING DEVICE FOR ITS PLACEMENT |
US5782864A (en) | 1997-04-03 | 1998-07-21 | Mitek Surgical Products, Inc. | Knotless suture system and method |
US5893592A (en) * | 1997-04-08 | 1999-04-13 | Ethicon Endo-Surgery, Inc. | Partially tied surgical knot |
US5749898A (en) | 1997-04-08 | 1998-05-12 | Ethicon Endo-Surgery, Inc. | Suture cartridge assembly for a surgical knot |
US5728109A (en) | 1997-04-08 | 1998-03-17 | Ethicon Endo-Surgery, Inc. | Surgical knot and method for its formation |
US5814069A (en) | 1997-04-08 | 1998-09-29 | Ethicon Endo-Surgery, Inc. | Load assist device for a suture cartridge |
US5897564A (en) * | 1997-04-08 | 1999-04-27 | Ethicon Endo-Surgery, Inc. | Endoscopic instrument assembly for fastening tissue |
US5846254A (en) | 1997-04-08 | 1998-12-08 | Ethicon Endo-Surgery, Inc. | Surgical instrument for forming a knot |
US5871490A (en) * | 1997-04-08 | 1999-02-16 | Ethicon Endo-Surgery, Inc. | Suture cartridge assembly for a surgical knot |
US5941439A (en) | 1997-05-14 | 1999-08-24 | Mitek Surgical Products, Inc. | Applicator and method for deploying a surgical fastener in tissue |
AU7377498A (en) | 1997-05-16 | 1998-12-08 | Norian Corporation | Implantable re-bar devices |
US5980524A (en) | 1997-06-02 | 1999-11-09 | Innovasive Devices, Inc. | Device for repairing a meniscal tear in a knee and method |
US6071292A (en) | 1997-06-28 | 2000-06-06 | Transvascular, Inc. | Transluminal methods and devices for closing, forming attachments to, and/or forming anastomotic junctions in, luminal anatomical structures |
US6692499B2 (en) * | 1997-07-02 | 2004-02-17 | Linvatec Biomaterials Oy | Surgical fastener for tissue treatment |
JP4068168B2 (en) | 1997-07-03 | 2008-03-26 | エシコン・インコーポレイテッド | Device for fixing autologous or artificial tendon grafts in bone |
US5895395A (en) * | 1997-07-17 | 1999-04-20 | Yeung; Teresa T. | Partial to full thickness suture device & method for endoscopic surgeries |
US5991705A (en) | 1997-07-23 | 1999-11-23 | Candle Distributed Solutions, Inc. | End-to-end response time measurement for computer programs using starting and ending queues |
US5899921A (en) | 1997-07-25 | 1999-05-04 | Innovasive Devices, Inc. | Connector device and method for surgically joining and securing flexible tissue repair members |
US6286746B1 (en) * | 1997-08-28 | 2001-09-11 | Axya Medical, Inc. | Fused loop of filamentous material and apparatus for making same |
US5893880A (en) * | 1997-08-28 | 1999-04-13 | Axya Medical Inc. | Fused loop filamentous material |
US6217591B1 (en) * | 1997-08-28 | 2001-04-17 | Axya Medical, Inc. | Suture fastening device |
US5954732A (en) | 1997-09-10 | 1999-09-21 | Hart; Charles C. | Suturing apparatus and method |
US6063106A (en) | 1997-09-19 | 2000-05-16 | Gibson; William Frits Stewart | Surgical spacer |
US6027523A (en) * | 1997-10-06 | 2000-02-22 | Arthrex, Inc. | Suture anchor with attached disk |
US6056778A (en) | 1997-10-29 | 2000-05-02 | Arthrex, Inc. | Meniscal repair device |
US5964783A (en) | 1997-11-07 | 1999-10-12 | Arthrex, Inc. | Suture anchor with insert-molded suture |
US5954747A (en) | 1997-11-20 | 1999-09-21 | Clark; Ron | Meniscus repair anchor system |
US5976127A (en) | 1998-01-14 | 1999-11-02 | Lax; Ronald | Soft tissue fixation devices |
US5921986A (en) | 1998-02-06 | 1999-07-13 | Bonutti; Peter M. | Bone suture |
US6024758A (en) * | 1998-02-23 | 2000-02-15 | Thal; Raymond | Two-part captured-loop knotless suture anchor assembly |
US5964765A (en) | 1998-04-16 | 1999-10-12 | Axya Medical, Inc. | Soft tissue fixation device |
US6066146A (en) | 1998-06-24 | 2000-05-23 | Carroll; Brendan J. | Laparascopic incision closure device |
US5993458A (en) | 1998-06-25 | 1999-11-30 | Ethicon, Inc. | Method of ultrasonically embedding bone anchors |
US7758614B2 (en) | 1998-07-08 | 2010-07-20 | Tornier, Inc. | Coupling member for knotless sutures and ligatures |
US6409743B1 (en) | 1998-07-08 | 2002-06-25 | Axya Medical, Inc. | Devices and methods for securing sutures and ligatures without knots |
US6174324B1 (en) * | 1998-07-13 | 2001-01-16 | Axya Medical, Inc. | Suture guide and fastener |
US6039753A (en) | 1998-07-16 | 2000-03-21 | Meislin; Robert | Single unit surgical fastener and method |
US6981974B2 (en) | 1998-08-07 | 2006-01-03 | Berger J Lee | Cannulated internally threaded bone screw with aperatured insert |
US6146387A (en) | 1998-08-26 | 2000-11-14 | Linvatec Corporation | Cannulated tissue anchor system |
US6165203A (en) | 1998-09-11 | 2000-12-26 | Bio Innovation, Ltd. | Suture anchor installation devices and methods |
US6056320A (en) | 1998-10-23 | 2000-05-02 | Chrysler Corporation | Energy absorbing occupant restraint system |
US6306159B1 (en) | 1998-12-23 | 2001-10-23 | Depuy Orthopaedics, Inc. | Meniscal repair device |
ATE324072T1 (en) * | 1998-12-30 | 2006-05-15 | Ethicon Inc | THREAD SECURING DEVICE |
EP1139777B1 (en) | 1998-12-30 | 2006-03-22 | Wm. Wrigley Jr. Company | Method of coating comestibles with syrup and powder |
EP1139883B1 (en) | 1998-12-31 | 2008-11-19 | Kensey Nash Corporation | Tissue fastening devices and delivery means |
US6074395A (en) | 1999-02-02 | 2000-06-13 | Linvatec Corporation | Cannulated tissue anchor insertion system |
US6306158B1 (en) | 1999-03-02 | 2001-10-23 | Edwin C. Bartlett | Suture anchor and associated method of implantation |
US6143017A (en) | 1999-03-17 | 2000-11-07 | Thal; Raymond | Free loop knotless suture anchor assembly |
US6045574A (en) * | 1999-04-01 | 2000-04-04 | Thal; Raymond | Sleeve and loop knotless suture anchor assembly |
US6752813B2 (en) | 1999-04-09 | 2004-06-22 | Evalve, Inc. | Methods and devices for capturing and fixing leaflets in valve repair |
US6096060A (en) | 1999-05-20 | 2000-08-01 | Linvatec Corporation | Bioabsorbable threaded soft tissue anchor system |
US6152934A (en) * | 1999-06-14 | 2000-11-28 | Ethicon Endo-Surgery, Inc. | Surgical knot tying instrument |
US7846180B2 (en) | 1999-06-22 | 2010-12-07 | Ethicon Endo-Surgery, Inc. | Tissue fixation devices and methods of fixing tissue |
US6206895B1 (en) | 1999-07-13 | 2001-03-27 | Scion Cardio-Vascular, Inc. | Suture with toggle and delivery system |
JP2003529395A (en) | 1999-07-19 | 2003-10-07 | グランピアン、ユニバーシティー、ホスピタルス、エヌエイチエス、トラスト | Medical equipment |
US6156039A (en) | 1999-08-06 | 2000-12-05 | Thal; Raymond | Snagging knotless suture anchor assembly |
US6554852B1 (en) * | 1999-08-25 | 2003-04-29 | Michael A. Oberlander | Multi-anchor suture |
US6736829B1 (en) | 1999-11-11 | 2004-05-18 | Linvatec Corporation | Toggle anchor and tool for insertion thereof |
US7887551B2 (en) | 1999-12-02 | 2011-02-15 | Smith & Nephew, Inc. | Soft tissue attachment and repair |
US7153312B1 (en) * | 1999-12-02 | 2006-12-26 | Smith & Nephew Inc. | Closure device and method for tissue repair |
AU782054B2 (en) | 1999-12-02 | 2005-06-30 | Smith & Nephew, Inc. | Wound closure devices and methods |
US6524317B1 (en) * | 1999-12-30 | 2003-02-25 | Opus Medical, Inc. | Method and apparatus for attaching connective tissues to bone using a knotless suture anchoring device |
US6635073B2 (en) | 2000-05-03 | 2003-10-21 | Peter M. Bonutti | Method of securing body tissue |
US20010010005A1 (en) | 2000-01-24 | 2001-07-26 | Kammerer Gene W. | Meniscal repair device |
DE10019922B4 (en) | 2000-04-20 | 2006-05-11 | Co.Don Aktiengesellschaft | Method and device for fastening and / or joining fabrics or fabric-like materials to a substrate |
US6669705B2 (en) | 2000-05-17 | 2003-12-30 | Axya Medical, Inc. | Apparatus and method for welding sutures |
US6585730B1 (en) | 2000-08-30 | 2003-07-01 | Opus Medical, Inc. | Method and apparatus for attaching connective tissues to bone using a knotless suture anchoring device |
US6923824B2 (en) | 2000-09-12 | 2005-08-02 | Axya Medical, Inc. | Apparatus and method for securing suture to bone |
US7037324B2 (en) | 2000-09-15 | 2006-05-02 | United States Surgical Corporation | Knotless tissue anchor |
US6641596B1 (en) | 2000-10-18 | 2003-11-04 | Ethicon, Inc. | Knotless bioabsorbable suture anchor system and method |
US6527795B1 (en) * | 2000-10-18 | 2003-03-04 | Ethicon, Inc. | Knotless suture anchor system and method of use |
JP4092196B2 (en) | 2000-10-23 | 2008-05-28 | タイコ ヘルスケア グループ リミテッド パートナーシップ | Absorbent fixture and application equipment |
US6520980B1 (en) * | 2000-11-02 | 2003-02-18 | Opus Medical, Inc. | Method and apparatus for attaching connective tissues to bone using a self-locking knotless suture anchoring device |
US6692516B2 (en) * | 2000-11-28 | 2004-02-17 | Linvatec Corporation | Knotless suture anchor and method for knotlessly securing tissue |
US8377100B2 (en) | 2000-12-08 | 2013-02-19 | Roger P. Jackson | Closure for open-headed medical implant |
AU2002234112B2 (en) | 2000-12-22 | 2006-12-14 | United States Surgical Corporation | Suture screw |
US6972019B2 (en) | 2001-01-23 | 2005-12-06 | Michelson Gary K | Interbody spinal implant with trailing end adapted to receive bone screws |
US6500184B1 (en) | 2001-01-31 | 2002-12-31 | Yung C. Chan | Suturing apparatus and method of suturing |
US6770076B2 (en) | 2001-02-12 | 2004-08-03 | Opus Medical, Inc. | Method and apparatus for attaching connective tissues to bone using a knotless suture anchoring device |
US7083638B2 (en) | 2001-02-12 | 2006-08-01 | Arthrocare Corporation | Method and apparatus for attaching connective tissues to bone using a knotless suture anchoring device |
US6533802B2 (en) | 2001-05-16 | 2003-03-18 | Smith & Nephew, Inc. | Endobutton continuous loop for bone-tendon-bone |
JP4302515B2 (en) * | 2001-07-16 | 2009-07-29 | デピュイ・プロダクツ・インコーポレイテッド | Stand-alone surgical apparatus and method |
US7235091B2 (en) | 2002-06-20 | 2007-06-26 | Brian Thornes | Apparatus and method for fixation of ankle syndesmosis |
US6901595B2 (en) * | 2001-09-29 | 2005-05-31 | Siebel Systems, Inc. | Method, apparatus, and system for implementing a framework to support a web-based application |
US6652563B2 (en) | 2001-10-02 | 2003-11-25 | Arthrex, Inc. | Suture anchor with internal suture loop |
US6862198B2 (en) | 2001-11-29 | 2005-03-01 | Iwatt, Inc. | PWM power converter with digital sampling control circuitry |
JP3453378B2 (en) | 2002-01-08 | 2003-10-06 | 科学技術振興事業団 | Radial aggregate of sharp-end multi-walled carbon nanotubes and method for producing the same |
US6855157B2 (en) * | 2002-02-04 | 2005-02-15 | Arthrocare Corporation | Method and apparatus for attaching connective tissues to bone using a knotless suture anchoring device |
US6972027B2 (en) | 2002-06-26 | 2005-12-06 | Stryker Endoscopy | Soft tissue repair system |
US7713286B2 (en) | 2002-11-15 | 2010-05-11 | Linvatec Corporation | Knotless suture anchor |
US20040138683A1 (en) | 2003-01-09 | 2004-07-15 | Walter Shelton | Suture arrow device and method of using |
EP1444959A1 (en) | 2003-02-07 | 2004-08-11 | DSM IP Assets B.V. | Bone fixing device |
US20040243131A1 (en) | 2003-02-07 | 2004-12-02 | Dirks Christiaan H.P. | Bone fixing device |
US20040267317A1 (en) | 2003-06-26 | 2004-12-30 | Laurence Higgins | Methods for attaching tissue to bone |
WO2005037150A1 (en) | 2003-10-16 | 2005-04-28 | Osteotech, Inc. | System and method for flexible correction of bony motion segment |
US7390332B2 (en) | 2004-02-24 | 2008-06-24 | Depuy Mitek, Inc. | Methods and devices for repairing tissue |
US7500983B1 (en) | 2004-06-09 | 2009-03-10 | Biomet Sports Medicine, Llc | Apparatus for soft tissue attachment |
US7819898B2 (en) | 2004-06-09 | 2010-10-26 | Biomet Sports Medicine, Llc | Method and apparatus for soft tissue fixation |
US7905903B2 (en) * | 2006-02-03 | 2011-03-15 | Biomet Sports Medicine, Llc | Method for tissue fixation |
US20060190042A1 (en) | 2004-11-05 | 2006-08-24 | Arthrotek, Inc. | Tissue repair assembly |
US7658751B2 (en) * | 2006-09-29 | 2010-02-09 | Biomet Sports Medicine, Llc | Method for implanting soft tissue |
US20070083236A1 (en) * | 2005-06-24 | 2007-04-12 | Smith & Nephew, Inc. | Methods and devices for tissue repair |
-
2000
- 2000-11-02 US US09/704,926 patent/US7153312B1/en not_active Expired - Fee Related
-
2001
- 2001-06-22 US US09/886,367 patent/US20020019649A1/en not_active Abandoned
-
2004
- 2004-12-30 US US11/025,837 patent/US8512375B2/en not_active Expired - Fee Related
-
2013
- 2013-07-17 US US13/944,682 patent/US8834524B2/en not_active Expired - Fee Related
-
2014
- 2014-08-07 US US14/454,243 patent/US9492160B2/en not_active Expired - Fee Related
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US8512374B2 (en) | 1998-12-30 | 2013-08-20 | Depuy Mitek, Llc | Soft tissue locking device |
US8323315B2 (en) | 1998-12-30 | 2012-12-04 | Depuy Mitek, Inc. | Suture locking device |
US7744613B2 (en) | 1999-06-25 | 2010-06-29 | Usgi Medical, Inc. | Apparatus and methods for forming and securing gastrointestinal tissue folds |
US20050245945A1 (en) * | 1999-06-25 | 2005-11-03 | Usgi Medical Inc. | Apparatus and methods for forming and securing gastrointestinal tissue folds |
US8343175B2 (en) | 1999-06-25 | 2013-01-01 | Usgi Medical, Inc. | Apparatus and methods for forming and securing gastrointestinal tissue folds |
US8574243B2 (en) | 1999-06-25 | 2013-11-05 | Usgi Medical, Inc. | Apparatus and methods for forming and securing gastrointestinal tissue folds |
US7704264B2 (en) | 1999-06-25 | 2010-04-27 | Usgi Medical, Inc. | Apparatus and methods for forming and securing gastrointestinal tissue folds |
US7955340B2 (en) | 1999-06-25 | 2011-06-07 | Usgi Medical, Inc. | Apparatus and methods for forming and securing gastrointestinal tissue folds |
US20100211086A1 (en) * | 1999-06-25 | 2010-08-19 | Usgi Medical, Inc. | Apparatus and methods for forming and securing gastrointestinal tissue folds |
US20040225183A1 (en) * | 1999-06-25 | 2004-11-11 | Usgi Medical | Apparatus and methods for forming and securing gastrointestinal tissue folds |
US20040225305A1 (en) * | 1999-06-25 | 2004-11-11 | Usgi Medical | Apparatus and methods for forming and securing gastrointestinal tissue folds |
US20050075653A1 (en) * | 1999-06-25 | 2005-04-07 | Usgi Medical Inc. | Apparatus and methods for forming and securing gastrointestinal tissue folds |
US20040010287A1 (en) * | 1999-08-09 | 2004-01-15 | Bonutti Peter M. | Method and apparatus for securing tissue |
US8845699B2 (en) | 1999-08-09 | 2014-09-30 | Bonutti Skeletal Innovations Llc | Method of securing tissue |
US8556977B2 (en) | 1999-10-20 | 2013-10-15 | Anulex Technologies, Inc. | Tissue anchoring system and method |
US8632590B2 (en) | 1999-10-20 | 2014-01-21 | Anulex Technologies, Inc. | Apparatus and methods for the treatment of the intervertebral disc |
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US20170340321A1 (en) * | 1999-10-20 | 2017-11-30 | Krt Investors, Inc. | Apparatus for the treatment of tissue |
US9095442B2 (en) | 1999-10-20 | 2015-08-04 | Krt Investors, Inc. | Method and apparatus for the treatment of the intervertebral disc annulus |
US9114025B2 (en) | 1999-10-20 | 2015-08-25 | Krt Investors, Inc. | Methods and devices for spinal disc annulus reconstruction and repair |
US20140316439A1 (en) * | 1999-10-20 | 2014-10-23 | Anulex Technologies, Inc. | Apparatus for the treatment of tissue |
US9833231B2 (en) | 1999-12-02 | 2017-12-05 | Smith & Nephew, Inc. | Apparatus for tissue repair |
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US7887551B2 (en) | 1999-12-02 | 2011-02-15 | Smith & Nephew, Inc. | Soft tissue attachment and repair |
US7651509B2 (en) | 1999-12-02 | 2010-01-26 | Smith & Nephew, Inc. | Methods and devices for tissue repair |
US8512375B2 (en) | 1999-12-02 | 2013-08-20 | Smith & Nephew, Inc. | Closure device and method for tissue repair |
US8366744B2 (en) | 1999-12-02 | 2013-02-05 | Smith & Nephew, Inc. | Apparatus for tissue repair |
US9545251B2 (en) | 1999-12-02 | 2017-01-17 | Smith & Nephew, Inc. | Apparatus for tissue repair |
US20050283192A1 (en) * | 1999-12-02 | 2005-12-22 | Torrie Paul A | Closure device and method for tissue repair |
US9295461B2 (en) | 1999-12-02 | 2016-03-29 | Smith & Nephew, Inc. | Methods for tissue repair |
US20100114162A1 (en) * | 1999-12-02 | 2010-05-06 | Smith & Nephew, Inc. | Methods for Tissue Repair |
US20050033363A1 (en) * | 1999-12-02 | 2005-02-10 | Ray Bojarski | Methods and devices for tissue repair |
US20100114161A1 (en) * | 1999-12-02 | 2010-05-06 | Smith & Nephew, Inc. | Apparatus for Tissue Repair |
US20030130694A1 (en) * | 1999-12-02 | 2003-07-10 | Ray Bojarski | Soft tissue attachment and repair |
US9220494B2 (en) | 1999-12-02 | 2015-12-29 | Smith & Nephew, Inc. | Methods for tissue repair |
US9884451B2 (en) | 2000-03-13 | 2018-02-06 | P Tech, Llc | Method of using ultrasonic vibration to secure body tissue |
US9067362B2 (en) | 2000-03-13 | 2015-06-30 | P Tech, Llc | Method of using ultrasonic vibration to secure body tissue with fastening element |
US8932330B2 (en) | 2000-03-13 | 2015-01-13 | P Tech, Llc | Method and device for securing body tissue |
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US9138222B2 (en) | 2000-03-13 | 2015-09-22 | P Tech, Llc | Method and device for securing body tissue |
US20060084994A1 (en) * | 2000-04-04 | 2006-04-20 | Anulex Technologies, Inc. | Devices and methods for the treatment of spinal disorders |
US20070233257A1 (en) * | 2000-04-04 | 2007-10-04 | Anulex Technologies, Inc. | Devices and Methods for Annular Repair of Intervertebral Discs |
US7905923B2 (en) | 2000-04-04 | 2011-03-15 | Anulex Technologies, Inc. | Devices and methods for annular repair of intervertebral discs |
US7753941B2 (en) | 2000-04-04 | 2010-07-13 | Anulex Technologies, Inc. | Devices and methods for annular repair of intervertebral discs |
US8814902B2 (en) | 2000-05-03 | 2014-08-26 | Bonutti Skeletal Innovations Llc | Method of securing body tissue |
US8366787B2 (en) | 2000-08-04 | 2013-02-05 | Depuy Products, Inc. | Hybrid biologic-synthetic bioabsorbable scaffolds |
US20070129811A1 (en) * | 2000-08-04 | 2007-06-07 | Plouhar Pamela L | Reinforced small intestinal submucosa |
US7799089B2 (en) | 2000-08-04 | 2010-09-21 | Depuy Orthopaedics, Inc. | Reinforced small intestinal submucosa |
US11229472B2 (en) | 2001-06-12 | 2022-01-25 | Cilag Gmbh International | Modular battery powered handheld surgical instrument with multiple magnetic position sensors |
US10835307B2 (en) | 2001-06-12 | 2020-11-17 | Ethicon Llc | Modular battery powered handheld surgical instrument containing elongated multi-layered shaft |
US7819918B2 (en) | 2001-07-16 | 2010-10-26 | Depuy Products, Inc. | Implantable tissue repair device |
US8025896B2 (en) | 2001-07-16 | 2011-09-27 | Depuy Products, Inc. | Porous extracellular matrix scaffold and method |
US20040143344A1 (en) * | 2001-07-16 | 2004-07-22 | Prasanna Malaviya | Implantable tissue repair device and method |
US20030021827A1 (en) * | 2001-07-16 | 2003-01-30 | Prasanna Malaviya | Hybrid biologic/synthetic porous extracellular matrix scaffolds |
US20080167716A1 (en) * | 2001-07-16 | 2008-07-10 | Schwartz Hebert E | Cartilage repair apparatus and method |
US7914808B2 (en) | 2001-07-16 | 2011-03-29 | Depuy Products, Inc. | Hybrid biologic/synthetic porous extracellular matrix scaffolds |
US20050027307A1 (en) * | 2001-07-16 | 2005-02-03 | Schwartz Herbert Eugene | Unitary surgical device and method |
US8012205B2 (en) | 2001-07-16 | 2011-09-06 | Depuy Products, Inc. | Cartilage repair and regeneration device |
US8337537B2 (en) | 2001-07-16 | 2012-12-25 | Depuy Products, Inc. | Device from naturally occurring biologically derived materials |
US20030049299A1 (en) * | 2001-07-16 | 2003-03-13 | Prasanna Malaviya | Porous delivery scaffold and method |
US8092529B2 (en) | 2001-07-16 | 2012-01-10 | Depuy Products, Inc. | Meniscus regeneration device |
US20030078617A1 (en) * | 2001-07-16 | 2003-04-24 | Schwartz Herbert E. | Unitary surgical device and method |
US20030083739A1 (en) * | 2001-09-24 | 2003-05-01 | Robert Cafferata | Rational drug therapy device and methods |
US9770238B2 (en) | 2001-12-03 | 2017-09-26 | P Tech, Llc | Magnetic positioning apparatus |
US10932869B2 (en) | 2002-03-20 | 2021-03-02 | P Tech, Llc | Robotic surgery |
US9271741B2 (en) | 2002-03-20 | 2016-03-01 | P Tech, Llc | Robotic ultrasonic energy system |
US9629687B2 (en) | 2002-03-20 | 2017-04-25 | P Tech, Llc | Robotic arthroplasty system |
US10265128B2 (en) | 2002-03-20 | 2019-04-23 | P Tech, Llc | Methods of using a robotic spine system |
US10368953B2 (en) | 2002-03-20 | 2019-08-06 | P Tech, Llc | Robotic system for fastening layers of body tissue together and method thereof |
US9149281B2 (en) | 2002-03-20 | 2015-10-06 | P Tech, Llc | Robotic system for engaging a fastener with body tissue |
US9155544B2 (en) | 2002-03-20 | 2015-10-13 | P Tech, Llc | Robotic systems and methods |
US9808318B2 (en) | 2002-03-20 | 2017-11-07 | P Tech, Llc | Robotic arthroplasty system |
US9192395B2 (en) | 2002-03-20 | 2015-11-24 | P Tech, Llc | Robotic fastening system |
US9585725B2 (en) | 2002-03-20 | 2017-03-07 | P Tech, Llc | Robotic arthroplasty system |
US9271779B2 (en) | 2002-03-20 | 2016-03-01 | P Tech, Llc | Methods of using a robotic spine system |
US10869728B2 (en) | 2002-03-20 | 2020-12-22 | P Tech, Llc | Robotic surgery |
US9486227B2 (en) | 2002-03-20 | 2016-11-08 | P Tech, Llc | Robotic retractor system |
US10959791B2 (en) | 2002-03-20 | 2021-03-30 | P Tech, Llc | Robotic surgery |
US9877793B2 (en) | 2002-03-20 | 2018-01-30 | P Tech, Llc | Robotic arthroplasty system |
US20050090139A1 (en) * | 2002-03-28 | 2005-04-28 | Rowland White | Contact |
US20040146296A1 (en) * | 2002-06-06 | 2004-07-29 | Irwin Gerszberg | Integrated electrical/optical hybrid communication system with revertive hitless switch |
US20090312792A1 (en) * | 2002-06-26 | 2009-12-17 | Stryker Endo | Soft tissue repair system |
US20060064126A1 (en) * | 2002-06-26 | 2006-03-23 | Fallin T W | Soft tissue repair system |
US6972027B2 (en) | 2002-06-26 | 2005-12-06 | Stryker Endoscopy | Soft tissue repair system |
KR20040006162A (en) * | 2002-07-11 | 2004-01-24 | 이은정 | Method for suture using button |
US20040166169A1 (en) * | 2002-07-15 | 2004-08-26 | Prasanna Malaviya | Porous extracellular matrix scaffold and method |
US9750496B2 (en) | 2002-08-27 | 2017-09-05 | P Tech, Llc | System for securing a portion of a body |
US8262676B2 (en) | 2002-12-11 | 2012-09-11 | Usgi Medical, Inc. | Apparatus and methods for forming gastrointestinal tissue approximations |
US7942884B2 (en) | 2002-12-11 | 2011-05-17 | Usgi Medical, Inc. | Methods for reduction of a gastric lumen |
US20040116949A1 (en) * | 2002-12-11 | 2004-06-17 | Ewers Richard C. | Apparatus and methods for forming gastrointestinal tissue approximations |
US8216260B2 (en) | 2002-12-11 | 2012-07-10 | Usgi Medical, Inc. | Apparatus and methods for forming and securing gastrointestinal tissue folds |
US20040147958A1 (en) * | 2002-12-11 | 2004-07-29 | Usgi Medical | Apparatus and methods for forming and securing gastrointestinal tissue folds |
US7942898B2 (en) | 2002-12-11 | 2011-05-17 | Usgi Medical, Inc. | Delivery systems and methods for gastric reduction |
US20050065536A1 (en) * | 2002-12-11 | 2005-03-24 | Usgi Medical Inc. | Apparatus and methods for forming gastrointestinal tissue approximations |
US8066719B2 (en) | 2002-12-11 | 2011-11-29 | Ewers Richard C | Apparatus and methods for forming gastrointestinal tissue approximations |
US7449025B1 (en) | 2002-12-17 | 2008-11-11 | O'donnell Pat D | Surgical instrument to secure body tissues |
WO2004062459A2 (en) | 2003-01-09 | 2004-07-29 | Linvatec Biomaterials Oy | Suture anchor device and method of using |
US20040138683A1 (en) * | 2003-01-09 | 2004-07-15 | Walter Shelton | Suture arrow device and method of using |
US7918845B2 (en) | 2003-01-15 | 2011-04-05 | Usgi Medical, Inc. | Endoluminal tool deployment system |
US20050065397A1 (en) * | 2003-01-15 | 2005-03-24 | Usgi Medical Inc. | Endoluminal tool deployment system |
US20040153074A1 (en) * | 2003-02-05 | 2004-08-05 | Bojarski Raymond A. | Tissue anchor and insertion tool |
US9314235B2 (en) * | 2003-02-05 | 2016-04-19 | Smith & Nephew, Inc. | Tissue anchor and insertion tool |
US9962162B2 (en) | 2003-04-30 | 2018-05-08 | P Tech, Llc | Tissue fastener and methods for using same |
US9060767B2 (en) | 2003-04-30 | 2015-06-23 | P Tech, Llc | Tissue fastener and methods for using same |
US9265498B2 (en) | 2003-06-11 | 2016-02-23 | Imds Llc | Compact line locks and methods |
US20100191285A1 (en) * | 2003-06-11 | 2010-07-29 | Medicinelodge, Inc. Dba Imds Co-Innovation | Compact Line Locks and Methods |
US8388655B2 (en) | 2003-06-11 | 2013-03-05 | Imds Corporation | Compact line locks and methods |
US9510817B2 (en) | 2003-12-12 | 2016-12-06 | Usgi Medical, Inc. | Apparatus for manipulating and securing tissue |
US10045871B2 (en) | 2003-12-12 | 2018-08-14 | Usgi Medical, Inc. | Apparatus for manipulating and securing tissue |
US7608092B1 (en) * | 2004-02-20 | 2009-10-27 | Biomet Sports Medicince, LLC | Method and apparatus for performing meniscus repair |
US8221454B2 (en) | 2004-02-20 | 2012-07-17 | Biomet Sports Medicine, Llc | Apparatus for performing meniscus repair |
US8696704B2 (en) | 2004-02-24 | 2014-04-15 | Depuy Mitek, Llc | Methods and devices for repairing tissue |
US20050187577A1 (en) * | 2004-02-24 | 2005-08-25 | David Selvitelli | Methods and devices for repairing tissue |
US20080188893A1 (en) * | 2004-02-24 | 2008-08-07 | Depuy Mitek, Inc. | Methods and devices for repairing tissue |
US7390332B2 (en) * | 2004-02-24 | 2008-06-24 | Depuy Mitek, Inc. | Methods and devices for repairing tissue |
US11730507B2 (en) | 2004-02-27 | 2023-08-22 | Cilag Gmbh International | Ultrasonic surgical shears and method for sealing a blood vessel using same |
US10874418B2 (en) | 2004-02-27 | 2020-12-29 | Ethicon Llc | Ultrasonic surgical shears and method for sealing a blood vessel using same |
US20050203489A1 (en) * | 2004-03-09 | 2005-09-15 | Usgi Medical Inc. | Apparatus and methods for performing mucosectomy |
US9888916B2 (en) | 2004-03-09 | 2018-02-13 | P Tech, Llc | Method and device for securing body tissue |
US20050203488A1 (en) * | 2004-03-09 | 2005-09-15 | Usgi Medical Inc. | Apparatus and methods for mapping out endoluminal gastrointestinal surgery |
US20050203500A1 (en) * | 2004-03-09 | 2005-09-15 | Usgi Medical Inc. | Apparatus and methods for mapping out endoluminal gastrointestinal surgery |
US20090270856A1 (en) * | 2004-03-09 | 2009-10-29 | Usgi Medical, Inc. | Apparatus and methods for performing mucosectomy |
US7703459B2 (en) | 2004-03-09 | 2010-04-27 | Usgi Medical, Inc. | Apparatus and methods for mapping out endoluminal gastrointestinal surgery |
US20050249771A1 (en) * | 2004-05-04 | 2005-11-10 | Prasanna Malaviya | Hybrid biologic-synthetic bioabsorbable scaffolds |
US20050249772A1 (en) * | 2004-05-04 | 2005-11-10 | Prasanna Malaviya | Hybrid biologic-synthetic bioabsorbable scaffolds |
US20050250985A1 (en) * | 2004-05-07 | 2005-11-10 | Usgi Medical Inc. | Self-locking removable apparatus and methods for manipulating and securing tissue |
US20050251176A1 (en) * | 2004-05-07 | 2005-11-10 | Usgi Medical Inc. | System for treating gastroesophageal reflux disease |
US8828027B2 (en) | 2004-05-07 | 2014-09-09 | U.S.G.I. Medical, Inc. | Tissue manipulation and securement system |
US20050251206A1 (en) * | 2004-05-07 | 2005-11-10 | Usgi Medical Corporation | Apparatus and methods for positioning and securing anchors |
US20050251205A1 (en) * | 2004-05-07 | 2005-11-10 | Usgi Medical Inc. | Apparatus and methods for positioning and securing anchors |
US7736378B2 (en) | 2004-05-07 | 2010-06-15 | Usgi Medical, Inc. | Apparatus and methods for positioning and securing anchors |
US7736374B2 (en) | 2004-05-07 | 2010-06-15 | Usgi Medical, Inc. | Tissue manipulation and securement system |
US20050251165A1 (en) * | 2004-05-07 | 2005-11-10 | Usgi Medical Inc. | Tissue manipulation and securement system |
US20050251189A1 (en) * | 2004-05-07 | 2005-11-10 | Usgi Medical Inc. | Multi-position tissue manipulation assembly |
US8236009B2 (en) | 2004-05-07 | 2012-08-07 | Usgi Medical, Inc. | Needle assembly for tissue manipulation |
US8257394B2 (en) | 2004-05-07 | 2012-09-04 | Usgi Medical, Inc. | Apparatus and methods for positioning and securing anchors |
US8308765B2 (en) | 2004-05-07 | 2012-11-13 | Usgi Medical, Inc. | Apparatus and methods for positioning and securing anchors |
US9421011B2 (en) * | 2004-05-07 | 2016-08-23 | Usgi Medical, Inc. | Apparatus and methods for positioning and securing anchors |
US20080200930A1 (en) * | 2004-05-07 | 2008-08-21 | Usgi Medical, Inc. | Apparatus for manipulating and securing tissue |
US20050251157A1 (en) * | 2004-05-07 | 2005-11-10 | Usgi Medical Inc. | Apparatus and methods for positioning and securing anchors |
US20050251208A1 (en) * | 2004-05-07 | 2005-11-10 | Usgi Medical Inc. | Linear anchors for anchoring to tissue |
US10172608B2 (en) | 2004-05-07 | 2019-01-08 | USGI Medical LLC | Apparatus and methods for positioning and securing anchors |
US8057511B2 (en) | 2004-05-07 | 2011-11-15 | Usgi Medical, Inc. | Apparatus and methods for positioning and securing anchors |
US11045341B2 (en) | 2004-05-07 | 2021-06-29 | Usgi Medical, Inc. | Apparatus for manipulating and securing tissue |
US8216253B2 (en) | 2004-05-07 | 2012-07-10 | Usgi Medical, Inc. | Apparatus for manipulating and securing tissue |
US8926634B2 (en) | 2004-05-07 | 2015-01-06 | Usgi Medical, Inc. | Apparatus and methods for manipulating and securing tissue |
US20050251162A1 (en) * | 2004-05-07 | 2005-11-10 | Usgi Medical Inc. | Apparatus and methods for manipulating and securing tissue |
US20060135971A1 (en) * | 2004-05-07 | 2006-06-22 | Usgi Medical Inc. | System for treating gastroesophageal reflux disease |
US8444657B2 (en) | 2004-05-07 | 2013-05-21 | Usgi Medical, Inc. | Apparatus and methods for rapid deployment of tissue anchors |
US8216252B2 (en) | 2004-05-07 | 2012-07-10 | Usgi Medical, Inc. | Tissue manipulation and securement system |
US7918869B2 (en) | 2004-05-07 | 2011-04-05 | Usgi Medical, Inc. | Methods and apparatus for performing endoluminal gastroplasty |
US20050250984A1 (en) * | 2004-05-07 | 2005-11-10 | Usgi Medical Inc. | Multiple removable apparatus and methods for manipulating and securing tissue |
US20050251161A1 (en) * | 2004-05-07 | 2005-11-10 | Usgi Medical Inc. | Needle assembly for tissue manipulation |
US20050251210A1 (en) * | 2004-05-07 | 2005-11-10 | Usgi Medical Inc. | Methods and apparatus for grasping and cinching tissue anchors |
US20050251209A1 (en) * | 2004-05-07 | 2005-11-10 | Usgi Medical Inc. | Apparatus and methods for positioning and securing anchors |
US20140288599A1 (en) * | 2004-05-07 | 2014-09-25 | Usgi Medical, Inc. | Apparatus and methods for positioning and securing anchors |
EP1750591A4 (en) * | 2004-05-07 | 2014-01-22 | Usgi Medical Inc | Apparatus and methods for positioning and securing anchors |
EP1750591A1 (en) * | 2004-05-07 | 2007-02-14 | USGI Medical Inc | Apparatus and methods for positioning and securing anchors |
US8926663B2 (en) | 2004-06-02 | 2015-01-06 | Kfx Medical Corporation | System and method for attaching soft tissue to bone |
US8951287B1 (en) | 2004-06-02 | 2015-02-10 | Kfx Medical Corporation | System and method for attaching soft tissue to bone |
US8529601B2 (en) | 2004-06-02 | 2013-09-10 | Kfx Medical Corporation | System and method for attaching soft tissue to bone |
US9655611B2 (en) | 2004-06-02 | 2017-05-23 | Kfx Medical, Llc | System and method for attaching soft tissue to bone |
US10561409B2 (en) | 2004-06-02 | 2020-02-18 | Kfx Medical, Llc | System and method for attaching soft tissue to bone |
US9044226B2 (en) | 2004-06-02 | 2015-06-02 | Kfx Medical Corporation | System and method for attaching soft tissue to bone |
US9414835B1 (en) | 2004-06-02 | 2016-08-16 | Kfx Medical, Llc | System and method for attaching soft tissue to bone |
US20090318966A1 (en) * | 2004-06-02 | 2009-12-24 | Kfx Medical Corporation | System and method for attaching soft tissue to bone |
US8062334B2 (en) | 2004-06-02 | 2011-11-22 | Kfx Medical Corporation | Suture anchor |
US8267964B2 (en) | 2004-06-02 | 2012-09-18 | Kfx Medical Corporation | System and method for attaching soft tissue to bone |
US8109969B1 (en) | 2004-06-02 | 2012-02-07 | Kfx Medical Corporation | System and method for attaching soft tissue to bone |
US8100942B1 (en) | 2004-06-02 | 2012-01-24 | Kfx Medical Corporation | System and method for attaching soft tissue to bone |
US8512378B2 (en) | 2004-06-02 | 2013-08-20 | Kfx Medical Corporation | Suture anchor |
US8740940B2 (en) | 2004-06-09 | 2014-06-03 | Usgi Medical, Inc. | Compressible tissue anchor assemblies |
US20050277983A1 (en) * | 2004-06-09 | 2005-12-15 | Usgi Medical Inc. | System for optimizing anchoring force |
US7736379B2 (en) | 2004-06-09 | 2010-06-15 | Usgi Medical, Inc. | Compressible tissue anchor assemblies |
US8382800B2 (en) | 2004-06-09 | 2013-02-26 | Usgi Medical, Inc. | Compressible tissue anchor assemblies |
US20050277981A1 (en) * | 2004-06-09 | 2005-12-15 | Usgi Medical Inc. | Apparatus and methods for optimizing anchoring force |
US7678135B2 (en) | 2004-06-09 | 2010-03-16 | Usgi Medical, Inc. | Compressible tissue anchor assemblies |
US7695493B2 (en) | 2004-06-09 | 2010-04-13 | Usgi Medical, Inc. | System for optimizing anchoring force |
US8206417B2 (en) | 2004-06-09 | 2012-06-26 | Usgi Medical Inc. | Apparatus and methods for optimizing anchoring force |
US20060217762A1 (en) * | 2004-06-09 | 2006-09-28 | Usgi Medical, Inc. | Compressible tissue anchor assemblies |
US20050277966A1 (en) * | 2004-06-09 | 2005-12-15 | Usgi Medical Inc. | Compressible tissue anchor assemblies |
US20060020276A1 (en) * | 2004-07-23 | 2006-01-26 | Usgi Medical Inc. | Apparatus and methods for achieving prolonged maintenance of gastrointestinal tissue folds |
US20090036922A1 (en) * | 2004-08-31 | 2009-02-05 | Riskin Daniel J | Systems and methods for closing a tissue opening |
US9028529B2 (en) | 2004-08-31 | 2015-05-12 | Dermaclip Us, Llc | Systems and methods for closing a tissue opening |
US20060200198A1 (en) * | 2004-08-31 | 2006-09-07 | Riskin Daniel J | Systems and methods for closing a tissue opening |
US9603596B2 (en) | 2004-08-31 | 2017-03-28 | Dermaclip Us, Llc | Systems and methods for closing a tissue opening |
US8157839B2 (en) | 2004-08-31 | 2012-04-17 | Wadsworth Medical Technologies, Inc. | Systems and methods for closing a tissue opening |
US20120046747A1 (en) * | 2004-09-07 | 2012-02-23 | Medicinelodge, Inc. Dba Imds Co-Innovation | Systems and methods for zipknot acl fixation |
US11006971B2 (en) | 2004-10-08 | 2021-05-18 | Ethicon Llc | Actuation mechanism for use with an ultrasonic surgical instrument |
US10537352B2 (en) | 2004-10-08 | 2020-01-21 | Ethicon Llc | Tissue pads for use with surgical instruments |
US9980761B2 (en) | 2004-10-26 | 2018-05-29 | P Tech, Llc | Tissue fixation system and method |
US9545268B2 (en) | 2004-10-26 | 2017-01-17 | P Tech, Llc | Devices and methods for stabilizing tissue and implants |
US9271766B2 (en) | 2004-10-26 | 2016-03-01 | P Tech, Llc | Devices and methods for stabilizing tissue and implants |
US9226828B2 (en) | 2004-10-26 | 2016-01-05 | P Tech, Llc | Devices and methods for stabilizing tissue and implants |
US20060089646A1 (en) * | 2004-10-26 | 2006-04-27 | Bonutti Peter M | Devices and methods for stabilizing tissue and implants |
US9999449B2 (en) | 2004-10-26 | 2018-06-19 | P Tech, Llc | Devices and methods for stabilizing tissue and implants |
US9463012B2 (en) | 2004-10-26 | 2016-10-11 | P Tech, Llc | Apparatus for guiding and positioning an implant |
US10813764B2 (en) | 2004-10-26 | 2020-10-27 | P Tech, Llc | Expandable introducer system and methods |
US11013542B2 (en) | 2004-10-26 | 2021-05-25 | P Tech, Llc | Tissue fixation system and method |
US9579129B2 (en) | 2004-10-26 | 2017-02-28 | P Tech, Llc | Devices and methods for stabilizing tissue and implants |
US9867706B2 (en) | 2004-10-26 | 2018-01-16 | P Tech, Llc | Tissue fastening system |
US9814453B2 (en) | 2004-10-26 | 2017-11-14 | P Tech, Llc | Deformable fastener system |
US10238378B2 (en) | 2004-10-26 | 2019-03-26 | P Tech, Llc | Tissue fixation system and method |
US9173647B2 (en) | 2004-10-26 | 2015-11-03 | P Tech, Llc | Tissue fixation system |
US11457958B2 (en) | 2004-10-26 | 2022-10-04 | P Tech, Llc | Devices and methods for stabilizing tissue and implants |
US20140066959A1 (en) * | 2004-10-26 | 2014-03-06 | P Tech, Llc | Devices and methods for stabilizing tissue and implants |
US20060128296A1 (en) * | 2004-10-29 | 2006-06-15 | Schwan Wade E | Intestine processing device and associated method |
US9504460B2 (en) * | 2004-11-05 | 2016-11-29 | Biomet Sports Medicine, LLC. | Soft tissue repair device and method |
US11109857B2 (en) | 2004-11-05 | 2021-09-07 | Biomet Sports Medicine, Llc | Soft tissue repair device and method |
US8128658B2 (en) | 2004-11-05 | 2012-03-06 | Biomet Sports Medicine, Llc | Method and apparatus for coupling soft tissue to bone |
US8137382B2 (en) | 2004-11-05 | 2012-03-20 | Biomet Sports Medicine, Llc | Method and apparatus for coupling anatomical features |
US8840645B2 (en) | 2004-11-05 | 2014-09-23 | Biomet Sports Medicine, Llc | Method and apparatus for coupling soft tissue to a bone |
US9572655B2 (en) | 2004-11-05 | 2017-02-21 | Biomet Sports Medicine, Llc | Method and apparatus for coupling soft tissue to a bone |
US20130035698A1 (en) * | 2004-11-05 | 2013-02-07 | Biomet Sports Medicine, Llc | Soft Tissue Repair Device And Associated Method |
US8551140B2 (en) | 2004-11-05 | 2013-10-08 | Biomet Sports Medicine, Llc | Method and apparatus for coupling soft tissue to bone |
US8118836B2 (en) | 2004-11-05 | 2012-02-21 | Biomet Sports Medicine, Llc | Method and apparatus for coupling soft tissue to a bone |
US10265064B2 (en) | 2004-11-05 | 2019-04-23 | Biomet Sports Medicine, Llc | Soft tissue repair device and method |
US9801708B2 (en) | 2004-11-05 | 2017-10-31 | Biomet Sports Medicine, Llc | Method and apparatus for coupling soft tissue to a bone |
US8303604B2 (en) | 2004-11-05 | 2012-11-06 | Biomet Sports Medicine, Llc | Soft tissue repair device and method |
US20060189993A1 (en) * | 2004-11-09 | 2006-08-24 | Arthrotek, Inc. | Soft tissue conduit device |
US20060247642A1 (en) * | 2004-11-09 | 2006-11-02 | Stone Kevin T | Tissue fixation device |
US8998949B2 (en) | 2004-11-09 | 2015-04-07 | Biomet Sports Medicine, Llc | Soft tissue conduit device |
US7914539B2 (en) | 2004-11-09 | 2011-03-29 | Biomet Sports Medicine, Llc | Tissue fixation device |
US8317825B2 (en) | 2004-11-09 | 2012-11-27 | Biomet Sports Medicine, Llc | Soft tissue conduit device and method |
US8034090B2 (en) | 2004-11-09 | 2011-10-11 | Biomet Sports Medicine, Llc | Tissue fixation device |
US20060122608A1 (en) * | 2004-12-08 | 2006-06-08 | Fallin T W | System and method for anchoring suture to bone |
US7572275B2 (en) | 2004-12-08 | 2009-08-11 | Stryker Endoscopy | System and method for anchoring suture to bone |
US20100160963A1 (en) * | 2004-12-08 | 2010-06-24 | Stryker Endoscopy | System and Method for Anchoring Suture to Bone |
US20060135638A1 (en) * | 2004-12-22 | 2006-06-22 | Pedrozo Hugo A | Method for organizing the assembly of collagen fibers and compositions formed therefrom |
US8128640B2 (en) | 2005-02-07 | 2012-03-06 | Ivy Sports Medicine LLC | System and method for all-inside suture fixation for implant attachment and soft tissue repair |
EP1855599A4 (en) * | 2005-02-07 | 2013-05-22 | Ivy Sports Medicine LLC | System and method for all-inside suture fixation for implant attachment and soft tissue repair |
US20060178680A1 (en) * | 2005-02-07 | 2006-08-10 | Regen Biologics, Inc. | System and method for all-inside suture fixation for implant attachment and soft tissue repair |
US20150190129A1 (en) * | 2005-02-07 | 2015-07-09 | Ivy Sports Medicine, Llc | System and method for all-inside suture fixation for implant attachment and soft tissue repair |
EP1855599A2 (en) * | 2005-02-07 | 2007-11-21 | Regen Biologics, Inc. | System and method for all-inside suture fixation for implant attachment and soft tissue repair |
US8808309B2 (en) | 2005-02-07 | 2014-08-19 | Ivy Sports Medicine, Llc | System and method for all-inside suture fixation for implant attachment and soft tissue repair |
US10548590B2 (en) * | 2005-02-07 | 2020-02-04 | Ivy Sports Medicine, Llc | System and method for all-inside suture fixation for implant attachment and soft tissue repair |
US9949732B2 (en) * | 2005-02-07 | 2018-04-24 | Ivy Sports Medicine, Llc | System and method for all-inside suture fixation for implant attachment and soft tissue repair |
EP3097865A3 (en) * | 2005-02-07 | 2017-02-15 | Ivy Sports Medicine, LLC. | System for all-inside suture fixation for implant attachment and soft tissue repair |
US20170027557A1 (en) * | 2005-02-07 | 2017-02-02 | Ivy Sports Medicine, Llc | System and method for all-inside suture fixation for implant attachment and soft tissue repair |
US9402616B2 (en) | 2005-02-07 | 2016-08-02 | Ivy Sports Medicine, Llc | System and method for all-inside suture fixation for implant attachment and soft tissue repair |
US9089323B2 (en) | 2005-02-22 | 2015-07-28 | P Tech, Llc | Device and method for securing body tissue |
US9980717B2 (en) | 2005-02-22 | 2018-05-29 | P Tech, Llc | Device and method for securing body tissue |
US7594922B1 (en) | 2005-04-07 | 2009-09-29 | Medicine Lodge, Inc | System and method for meniscal repair through a meniscal capsular tunnel |
US20100010497A1 (en) * | 2005-04-07 | 2010-01-14 | Medicinelodge, Inc. | System and method for meniscal repair through a meniscal capsular tunnel |
US20100152772A1 (en) * | 2005-04-29 | 2010-06-17 | Gerard Brett | Interventional medical closure device |
US20100222796A1 (en) * | 2005-04-29 | 2010-09-02 | Vivasure Medical Ltd. | Interventional medical closure device |
US7753935B2 (en) | 2005-04-29 | 2010-07-13 | Vivasure Medical Limited | Interventional medical closure device |
US8906050B2 (en) | 2005-04-29 | 2014-12-09 | Vivasure Medical Limited | Interventional medical closure device |
US8523869B2 (en) | 2005-05-20 | 2013-09-03 | Smith & Nephew, Inc. | Patello-femoral joint implant and instrumentation |
US20060271073A1 (en) * | 2005-05-26 | 2006-11-30 | Usgi Medical Inc. | Methods and apparatus for securing and deploying tissue anchors |
US20060271074A1 (en) * | 2005-05-26 | 2006-11-30 | Ewers Richard C | Methods and apparatus for securing and deploying tissue anchors |
US9585651B2 (en) | 2005-05-26 | 2017-03-07 | Usgi Medical, Inc. | Methods and apparatus for securing and deploying tissue anchors |
US8298291B2 (en) | 2005-05-26 | 2012-10-30 | Usgi Medical, Inc. | Methods and apparatus for securing and deploying tissue anchors |
JP2008543509A (en) * | 2005-06-24 | 2008-12-04 | スミス アンド ネフュー インコーポレーテッド | Tissue repair |
US8623051B2 (en) | 2005-06-24 | 2014-01-07 | Smith & Nephew, Inc. | Tissue repair device |
AU2006261843B2 (en) * | 2005-06-24 | 2012-11-01 | Smith & Nephew, Inc. | Tissue repair |
US20060293709A1 (en) * | 2005-06-24 | 2006-12-28 | Bojarski Raymond A | Tissue repair device |
WO2007002561A1 (en) | 2005-06-24 | 2007-01-04 | Smith & Nephew, Inc. | Tissue repair |
US20070083236A1 (en) * | 2005-06-24 | 2007-04-12 | Smith & Nephew, Inc. | Methods and devices for tissue repair |
US9173653B2 (en) * | 2005-06-24 | 2015-11-03 | Smith & Nephew, Inc. | Tissue repair device |
US20140114353A1 (en) * | 2005-06-24 | 2014-04-24 | Smith & Nephew, Inc. | Tissue repair device |
US20070010857A1 (en) * | 2005-07-05 | 2007-01-11 | Mitralign, Inc. | Tissue anchor, anchoring system and methods of using the same |
US9814454B2 (en) | 2005-07-05 | 2017-11-14 | Mitralign, Inc. | Tissue anchor and anchoring system |
EP2979647A1 (en) * | 2005-07-05 | 2016-02-03 | Mitralign, Inc. | Tissue anchor and anchoring system |
US9259218B2 (en) | 2005-07-05 | 2016-02-16 | Mitralign, Inc. | Tissue anchor and anchoring system |
US20090076547A1 (en) * | 2005-07-05 | 2009-03-19 | Mitralign, Inc. | Tissue anchor and anchoring system |
US8951285B2 (en) | 2005-07-05 | 2015-02-10 | Mitralign, Inc. | Tissue anchor, anchoring system and methods of using the same |
US10695046B2 (en) | 2005-07-05 | 2020-06-30 | Edwards Lifesciences Corporation | Tissue anchor and anchoring system |
US8951286B2 (en) | 2005-07-05 | 2015-02-10 | Mitralign, Inc. | Tissue anchor and anchoring system |
US20070043255A1 (en) * | 2005-08-22 | 2007-02-22 | O'donnell Pat D | Surgical instrument for treating female pelvic prolapse |
US8128552B2 (en) | 2005-08-22 | 2012-03-06 | O'donnell Pat D | Surgical instrument for treating female pelvic prolapse |
US10441269B1 (en) | 2005-10-05 | 2019-10-15 | P Tech, Llc | Deformable fastener system |
US10376259B2 (en) | 2005-10-05 | 2019-08-13 | P Tech, Llc | Deformable fastener system |
US11219446B2 (en) | 2005-10-05 | 2022-01-11 | P Tech, Llc | Deformable fastener system |
US10856896B2 (en) | 2005-10-14 | 2020-12-08 | Ethicon Llc | Ultrasonic device for cutting and coagulating |
US20080065120A1 (en) * | 2005-10-31 | 2008-03-13 | Zannis Anthony D | Surgical instrument, kit and method for creating mattress-type stitches |
US20070167950A1 (en) * | 2005-12-22 | 2007-07-19 | Tauro Joseph C | System and method for attaching soft tissue to bone |
US10779848B2 (en) | 2006-01-20 | 2020-09-22 | Ethicon Llc | Ultrasound medical instrument having a medical ultrasonic blade |
US20070175488A1 (en) * | 2006-01-27 | 2007-08-02 | Usgi Medical Inc. | Methods and apparatus for revision of obesity procedures |
US8726909B2 (en) | 2006-01-27 | 2014-05-20 | Usgi Medical, Inc. | Methods and apparatus for revision of obesity procedures |
US9538998B2 (en) | 2006-02-03 | 2017-01-10 | Biomet Sports Medicine, Llc | Method and apparatus for fracture fixation |
US9492158B2 (en) | 2006-02-03 | 2016-11-15 | Biomet Sports Medicine, Llc | Method and apparatus for coupling soft tissue to a bone |
US20130211452A1 (en) * | 2006-02-03 | 2013-08-15 | Biomet Sports Medicine, Llc | Soft Tissue Repair Device And Associated Methods |
US20110087284A1 (en) * | 2006-02-03 | 2011-04-14 | Biomet Sports Medicine, Llc | Soft Tissue Repair and Conduit Device |
US11896210B2 (en) | 2006-02-03 | 2024-02-13 | Biomet Sports Medicine, Llc | Method and apparatus for coupling soft tissue to a bone |
US20190365376A1 (en) * | 2006-02-03 | 2019-12-05 | Biomet Sports Medicine, Llc | Soft tissue repair assembly and associated method |
US9468433B2 (en) | 2006-02-03 | 2016-10-18 | Biomet Sports Medicine, Llc | Method and apparatus for forming a self-locking adjustable loop |
US20110106153A1 (en) * | 2006-02-03 | 2011-05-05 | Biomet Sports Medicine, Llc | Method and Apparatus for Sternal Closure |
US9498204B2 (en) | 2006-02-03 | 2016-11-22 | Biomet Sports Medicine, Llc | Method and apparatus for coupling anatomical features |
US10517587B2 (en) | 2006-02-03 | 2019-12-31 | Biomet Sports Medicine, Llc | Method and apparatus for forming a self-locking adjustable loop |
US11819205B2 (en) * | 2006-02-03 | 2023-11-21 | Biomet Sports Medicine, Llc | Soft tissue repair device and associated methods |
US20170128061A1 (en) * | 2006-02-03 | 2017-05-11 | Biomet Sports Medicine, Llc | Soft tissue repair device and associated methods |
US10542967B2 (en) | 2006-02-03 | 2020-01-28 | Biomet Sports Medicine, Llc | Method and apparatus for coupling soft tissue to a bone |
US8574235B2 (en) | 2006-02-03 | 2013-11-05 | Biomet Sports Medicine, Llc | Method for trochanteric reattachment |
US9510821B2 (en) | 2006-02-03 | 2016-12-06 | Biomet Sports Medicine, Llc | Method and apparatus for coupling anatomical features |
US11116495B2 (en) | 2006-02-03 | 2021-09-14 | Biomet Sports Medicine, Llc | Soft tissue repair assembly and associated method |
US7749250B2 (en) | 2006-02-03 | 2010-07-06 | Biomet Sports Medicine, Llc | Soft tissue repair assembly and associated method |
US8597327B2 (en) * | 2006-02-03 | 2013-12-03 | Biomet Manufacturing, Llc | Method and apparatus for sternal closure |
US8608777B2 (en) | 2006-02-03 | 2013-12-17 | Biomet Sports Medicine | Method and apparatus for coupling soft tissue to a bone |
US9414833B2 (en) | 2006-02-03 | 2016-08-16 | Biomet Sports Medicine, Llc | Soft tissue repair assembly and associated method |
US9408599B2 (en) | 2006-02-03 | 2016-08-09 | Biomet Sports Medicine, Llc | Method and apparatus for coupling soft tissue to a bone |
US9642661B2 (en) | 2006-02-03 | 2017-05-09 | Biomet Sports Medicine, Llc | Method and Apparatus for Sternal Closure |
US11786236B2 (en) | 2006-02-03 | 2023-10-17 | Biomet Sports Medicine, Llc | Method and apparatus for coupling anatomical features |
US8632569B2 (en) | 2006-02-03 | 2014-01-21 | Biomet Sports Medicine, Llc | Soft tissue repair device and associated methods |
US9402621B2 (en) | 2006-02-03 | 2016-08-02 | Biomet Sports Medicine, LLC. | Method for tissue fixation |
US20110160768A1 (en) * | 2006-02-03 | 2011-06-30 | Biomet Sports Medicine, Llc | Soft Tissue Repair Device and Associated Methods |
US8652171B2 (en) | 2006-02-03 | 2014-02-18 | Biomet Sports Medicine, Llc | Method and apparatus for soft tissue fixation |
US10595851B2 (en) | 2006-02-03 | 2020-03-24 | Biomet Sports Medicine, Llc | Method and apparatus for coupling soft tissue to a bone |
US8652172B2 (en) | 2006-02-03 | 2014-02-18 | Biomet Sports Medicine, Llc | Flexible anchors for tissue fixation |
US11730464B2 (en) * | 2006-02-03 | 2023-08-22 | Biomet Sports Medicine, Llc | Soft tissue repair assembly and associated method |
US9510819B2 (en) * | 2006-02-03 | 2016-12-06 | Biomet Sports Medicine, Llc | Soft tissue repair device and associated methods |
US20070185532A1 (en) * | 2006-02-03 | 2007-08-09 | Arthrotek, Inc. | Soft tissue repair assembly and associated method |
US11723648B2 (en) | 2006-02-03 | 2023-08-15 | Biomet Sports Medicine, Llc | Method and apparatus for soft tissue fixation |
US9993241B2 (en) | 2006-02-03 | 2018-06-12 | Biomet Sports Medicine, Llc | Method and apparatus for forming a self-locking adjustable loop |
US20180161030A1 (en) * | 2006-02-03 | 2018-06-14 | Biomet Sports Medicine, Llc | Soft tissue repair device and associated methods |
US10441264B2 (en) | 2006-02-03 | 2019-10-15 | Biomet Sports Medicine, Llc | Soft tissue repair assembly and associated method |
US10603029B2 (en) | 2006-02-03 | 2020-03-31 | Biomet Sports Medicine, Llc | Method and apparatus for coupling soft tissue to bone |
US10004588B2 (en) | 2006-02-03 | 2018-06-26 | Biomet Sports Medicine, Llc | Method and apparatus for fixation of an ACL graft |
US10675073B2 (en) | 2006-02-03 | 2020-06-09 | Biomet Sports Medicine, Llc | Method and apparatus for sternal closure |
US9532777B2 (en) | 2006-02-03 | 2017-01-03 | Biomet Sports Medicine, Llc | Method and apparatus for coupling soft tissue to a bone |
US10687803B2 (en) | 2006-02-03 | 2020-06-23 | Biomet Sports Medicine, Llc | Method and apparatus for coupling soft tissue to a bone |
US10695052B2 (en) | 2006-02-03 | 2020-06-30 | Biomet Sports Medicine, Llc | Method and apparatus for coupling soft tissue to a bone |
US8721684B2 (en) | 2006-02-03 | 2014-05-13 | Biomet Sports Medicine, Llc | Method and apparatus for coupling anatomical features |
US20140135835A1 (en) * | 2006-02-03 | 2014-05-15 | Biomet Sports Medicine, Llc | Soft Tissue Repair Device And Associated Methods |
US10702259B2 (en) | 2006-02-03 | 2020-07-07 | Biomet Sports Medicine, Llc | Soft tissue repair assembly and associated method |
US10004489B2 (en) | 2006-02-03 | 2018-06-26 | Biomet Sports Medicine, Llc | Method and apparatus for coupling soft tissue to a bone |
US20100268275A1 (en) * | 2006-02-03 | 2010-10-21 | Biomet Sports Medicine, Llc | Soft Tissue Repair Assembly and Associated Method |
US7909851B2 (en) * | 2006-02-03 | 2011-03-22 | Biomet Sports Medicine, Llc | Soft tissue repair device and associated methods |
US9801620B2 (en) | 2006-02-03 | 2017-10-31 | Biomet Sports Medicine, Llc | Method and apparatus for coupling soft tissue to bone |
US9622736B2 (en) * | 2006-02-03 | 2017-04-18 | Biomet Sports Medicine, Llc | Soft tissue repair device and associated methods |
US10716557B2 (en) | 2006-02-03 | 2020-07-21 | Biomet Sports Medicine, Llc | Method and apparatus for coupling anatomical features |
US9561025B2 (en) | 2006-02-03 | 2017-02-07 | Biomet Sports Medicine, Llc | Soft tissue repair device and associated methods |
US9271713B2 (en) | 2006-02-03 | 2016-03-01 | Biomet Sports Medicine, Llc | Method and apparatus for tensioning a suture |
US8771316B2 (en) | 2006-02-03 | 2014-07-08 | Biomet Sports Medicine, Llc | Method and apparatus for coupling anatomical features |
US9005287B2 (en) | 2006-02-03 | 2015-04-14 | Biomet Sports Medicine, Llc | Method for bone reattachment |
US10022118B2 (en) | 2006-02-03 | 2018-07-17 | Biomet Sports Medicine, Llc | Method and apparatus for coupling soft tissue to a bone |
US10729421B2 (en) | 2006-02-03 | 2020-08-04 | Biomet Sports Medicine, Llc | Method and apparatus for soft tissue fixation |
US11065103B2 (en) | 2006-02-03 | 2021-07-20 | Biomet Sports Medicine, Llc | Method and apparatus for fixation of an ACL graft |
US11617572B2 (en) | 2006-02-03 | 2023-04-04 | Biomet Sports Medicine, Llc | Soft tissue repair device and associated methods |
US10729430B2 (en) | 2006-02-03 | 2020-08-04 | Biomet Sports Medicine, Llc | Method and apparatus for coupling soft tissue to a bone |
US8409253B2 (en) * | 2006-02-03 | 2013-04-02 | Biomet Sports Medicine, Llc | Soft tissue repair assembly and associated method |
US11259792B2 (en) | 2006-02-03 | 2022-03-01 | Biomet Sports Medicine, Llc | Method and apparatus for coupling anatomical features |
US7905903B2 (en) | 2006-02-03 | 2011-03-15 | Biomet Sports Medicine, Llc | Method for tissue fixation |
US20200367880A1 (en) * | 2006-02-03 | 2020-11-26 | Biomet Sports Medicine, Llc | Soft tissue repair device and associated methods |
US20160022261A1 (en) * | 2006-02-03 | 2016-01-28 | Biomet Sports Medicine, Llc | Soft tissue repair device and associated methods |
US11589859B2 (en) | 2006-02-03 | 2023-02-28 | Biomet Sports Medicine, Llc | Method and apparatus for coupling soft tissue to bone |
US10092288B2 (en) | 2006-02-03 | 2018-10-09 | Biomet Sports Medicine, Llc | Method and apparatus for coupling soft tissue to a bone |
US11471147B2 (en) | 2006-02-03 | 2022-10-18 | Biomet Sports Medicine, Llc | Method and apparatus for coupling soft tissue to a bone |
US7857830B2 (en) | 2006-02-03 | 2010-12-28 | Biomet Sports Medicine, Llc | Soft tissue repair and conduit device |
US9763656B2 (en) | 2006-02-03 | 2017-09-19 | Biomet Sports Medicine, Llc | Method and apparatus for soft tissue fixation |
US10098629B2 (en) | 2006-02-03 | 2018-10-16 | Biomet Sports Medicine, Llc | Method and apparatus for coupling soft tissue to a bone |
US8361113B2 (en) | 2006-02-03 | 2013-01-29 | Biomet Sports Medicine, Llc | Method and apparatus for coupling soft tissue to a bone |
US7905904B2 (en) | 2006-02-03 | 2011-03-15 | Biomet Sports Medicine, Llc | Soft tissue repair device and associated methods |
US10154837B2 (en) | 2006-02-03 | 2018-12-18 | Biomet Sports Medicine, Llc | Method and apparatus for coupling soft tissue to a bone |
US10932770B2 (en) * | 2006-02-03 | 2021-03-02 | Biomet Sports Medicine, Llc | Soft tissue repair device and associated methods |
US10398428B2 (en) | 2006-02-03 | 2019-09-03 | Biomet Sports Medicine, Llc | Method and apparatus for coupling anatomical features |
US20110218625A1 (en) * | 2006-02-03 | 2011-09-08 | Biomet Sports Medicine, Llc | Method and Apparatus for Fixation of an ACL Graft |
US8968364B2 (en) * | 2006-02-03 | 2015-03-03 | Biomet Sports Medicine, Llc | Method and apparatus for fixation of an ACL graft |
US11446019B2 (en) | 2006-02-03 | 2022-09-20 | Biomet Sports Medicine, Llc | Method and apparatus for coupling soft tissue to a bone |
US9603591B2 (en) | 2006-02-03 | 2017-03-28 | Biomet Sports Medicine, Llc | Flexible anchors for tissue fixation |
US10973507B2 (en) | 2006-02-03 | 2021-04-13 | Biomet Sports Medicine, Llc | Method and apparatus for coupling soft tissue to a bone |
US8337525B2 (en) | 2006-02-03 | 2012-12-25 | Biomet Sports Medicine, Llc | Soft tissue repair device and associated methods |
US10987099B2 (en) | 2006-02-03 | 2021-04-27 | Biomet Sports Medicine, Llc | Method for tissue fixation |
US11284884B2 (en) | 2006-02-03 | 2022-03-29 | Biomet Sports Medicine, Llc | Method and apparatus for coupling soft tissue to a bone |
US10251637B2 (en) * | 2006-02-03 | 2019-04-09 | Biomet Sports Medicine, Llc | Soft tissue repair device and associated methods |
US11039826B2 (en) | 2006-02-03 | 2021-06-22 | Biomet Sports Medicine, Llc | Method and apparatus for forming a self-locking adjustable loop |
US8088130B2 (en) | 2006-02-03 | 2012-01-03 | Biomet Sports Medicine, Llc | Method and apparatus for coupling soft tissue to a bone |
US8932331B2 (en) | 2006-02-03 | 2015-01-13 | Biomet Sports Medicine, Llc | Method and apparatus for coupling soft tissue to bone |
US8936621B2 (en) | 2006-02-03 | 2015-01-20 | Biomet Sports Medicine, Llc | Method and apparatus for forming a self-locking adjustable loop |
US10321906B2 (en) | 2006-02-03 | 2019-06-18 | Biomet Sports Medicine, Llc | Method for tissue fixation |
US9173651B2 (en) | 2006-02-03 | 2015-11-03 | Biomet Sports Medicine, Llc | Soft tissue repair device and associated methods |
US8298262B2 (en) | 2006-02-03 | 2012-10-30 | Biomet Sports Medicine, Llc | Method for tissue fixation |
US9149267B2 (en) | 2006-02-03 | 2015-10-06 | Biomet Sports Medicine, Llc | Method and apparatus for coupling soft tissue to a bone |
US8292921B2 (en) * | 2006-02-03 | 2012-10-23 | Biomet Sports Medicine, Llc | Soft tissue repair device and associated methods |
US8273106B2 (en) * | 2006-02-03 | 2012-09-25 | Biomet Sports Medicine, Llc | Soft tissue repair and conduit device |
US11317907B2 (en) | 2006-02-03 | 2022-05-03 | Biomet Sports Medicine, Llc | Method and apparatus for forming a self-locking adjustable loop |
US11311287B2 (en) | 2006-02-03 | 2022-04-26 | Biomet Sports Medicine, Llc | Method for tissue fixation |
US11253296B2 (en) | 2006-02-07 | 2022-02-22 | P Tech, Llc | Methods and devices for intracorporeal bonding of implants with thermal energy |
US9439642B2 (en) | 2006-02-07 | 2016-09-13 | P Tech, Llc | Methods and devices for utilizing bondable materials |
US8496657B2 (en) | 2006-02-07 | 2013-07-30 | P Tech, Llc. | Methods for utilizing vibratory energy to weld, stake and/or remove implants |
US9610073B2 (en) | 2006-02-07 | 2017-04-04 | P Tech, Llc | Methods and devices for intracorporeal bonding of implants with thermal energy |
US9421005B2 (en) | 2006-02-07 | 2016-08-23 | P Tech, Llc | Methods and devices for intracorporeal bonding of implants with thermal energy |
US11129645B2 (en) | 2006-02-07 | 2021-09-28 | P Tech, Llc | Methods of securing a fastener |
US11278331B2 (en) | 2006-02-07 | 2022-03-22 | P Tech Llc | Method and devices for intracorporeal bonding of implants with thermal energy |
US11134995B2 (en) | 2006-02-07 | 2021-10-05 | P Tech, Llc | Method and devices for intracorporeal bonding of implants with thermal energy |
US20070219558A1 (en) * | 2006-03-15 | 2007-09-20 | Allen Deutsch | Method and apparatus for arthroscopic surgery using suture anchors |
US8758405B2 (en) * | 2006-03-23 | 2014-06-24 | Ethicon Endo-Surgery, Inc | Suture tensioning device |
US20070225736A1 (en) * | 2006-03-23 | 2007-09-27 | Ethicon Endo-Surgery, Inc. | Suture Tensioning Device |
US11246638B2 (en) | 2006-05-03 | 2022-02-15 | P Tech, Llc | Methods and devices for utilizing bondable materials |
US20070288023A1 (en) * | 2006-06-12 | 2007-12-13 | Greg Pellegrino | Soft tissue repair using tissue augments and bone anchors |
US8870916B2 (en) | 2006-07-07 | 2014-10-28 | USGI Medical, Inc | Low profile tissue anchors, tissue anchor systems, and methods for their delivery and use |
US8251998B2 (en) | 2006-08-16 | 2012-08-28 | Biomet Sports Medicine, Llc | Chondral defect repair |
US8777956B2 (en) | 2006-08-16 | 2014-07-15 | Biomet Sports Medicine, Llc | Chondral defect repair |
AU2007345245B2 (en) * | 2006-09-27 | 2013-03-14 | Smith & Nephew, Inc. | Methods and devices for tissue repair |
US9788876B2 (en) | 2006-09-29 | 2017-10-17 | Biomet Sports Medicine, Llc | Fracture fixation device |
US8801783B2 (en) | 2006-09-29 | 2014-08-12 | Biomet Sports Medicine, Llc | Prosthetic ligament system for knee joint |
US9486211B2 (en) | 2006-09-29 | 2016-11-08 | Biomet Sports Medicine, Llc | Method for implanting soft tissue |
US9918826B2 (en) | 2006-09-29 | 2018-03-20 | Biomet Sports Medicine, Llc | Scaffold for spring ligament repair |
US7658751B2 (en) | 2006-09-29 | 2010-02-09 | Biomet Sports Medicine, Llc | Method for implanting soft tissue |
US10004493B2 (en) | 2006-09-29 | 2018-06-26 | Biomet Sports Medicine, Llc | Method for implanting soft tissue |
US10835232B2 (en) | 2006-09-29 | 2020-11-17 | Biomet Sports Medicine, Llc | Fracture fixation device |
US8500818B2 (en) | 2006-09-29 | 2013-08-06 | Biomet Manufacturing, Llc | Knee prosthesis assembly with ligament link |
US11259794B2 (en) | 2006-09-29 | 2022-03-01 | Biomet Sports Medicine, Llc | Method for implanting soft tissue |
US8231654B2 (en) | 2006-09-29 | 2012-07-31 | Biomet Sports Medicine, Llc | Adjustable knotless loops |
US10517714B2 (en) | 2006-09-29 | 2019-12-31 | Biomet Sports Medicine, Llc | Ligament system for knee joint |
US9078644B2 (en) | 2006-09-29 | 2015-07-14 | Biomet Sports Medicine, Llc | Fracture fixation device |
US10743925B2 (en) | 2006-09-29 | 2020-08-18 | Biomet Sports Medicine, Llc | Fracture fixation device |
US8562647B2 (en) | 2006-09-29 | 2013-10-22 | Biomet Sports Medicine, Llc | Method and apparatus for securing soft tissue to bone |
US20080082128A1 (en) * | 2006-09-29 | 2008-04-03 | Arthrotek, Inc. | Method and apparatus for forming a self-locking adjustable suture loop |
US8562645B2 (en) | 2006-09-29 | 2013-10-22 | Biomet Sports Medicine, Llc | Method and apparatus for forming a self-locking adjustable loop |
US11096684B2 (en) | 2006-09-29 | 2021-08-24 | Biomet Sports Medicine, Llc | Method and apparatus for forming a self-locking adjustable loop |
US9724090B2 (en) | 2006-09-29 | 2017-08-08 | Biomet Manufacturing, Llc | Method and apparatus for attaching soft tissue to bone |
US9681940B2 (en) | 2006-09-29 | 2017-06-20 | Biomet Sports Medicine, Llc | Ligament system for knee joint |
US7959650B2 (en) | 2006-09-29 | 2011-06-14 | Biomet Sports Medicine, Llc | Adjustable knotless loops |
US11672527B2 (en) | 2006-09-29 | 2023-06-13 | Biomet Sports Medicine, Llc | Method for implanting soft tissue |
US9414925B2 (en) | 2006-09-29 | 2016-08-16 | Biomet Manufacturing, Llc | Method of implanting a knee prosthesis assembly with a ligament link |
US11376115B2 (en) | 2006-09-29 | 2022-07-05 | Biomet Sports Medicine, Llc | Prosthetic ligament system for knee joint |
US9833230B2 (en) | 2006-09-29 | 2017-12-05 | Biomet Sports Medicine, Llc | Fracture fixation device |
US10398430B2 (en) | 2006-09-29 | 2019-09-03 | Biomet Sports Medicine, Llc | Method for implanting soft tissue |
US10695045B2 (en) | 2006-09-29 | 2020-06-30 | Biomet Sports Medicine, Llc | Method and apparatus for attaching soft tissue to bone |
US9539003B2 (en) | 2006-09-29 | 2017-01-10 | Biomet Sports Medicine, LLC. | Method and apparatus for forming a self-locking adjustable loop |
US10349931B2 (en) | 2006-09-29 | 2019-07-16 | Biomet Sports Medicine, Llc | Fracture fixation device |
US8672969B2 (en) | 2006-09-29 | 2014-03-18 | Biomet Sports Medicine, Llc | Fracture fixation device |
US8672968B2 (en) | 2006-09-29 | 2014-03-18 | Biomet Sports Medicine, Llc | Method for implanting soft tissue |
US10610217B2 (en) | 2006-09-29 | 2020-04-07 | Biomet Sports Medicine, Llc | Method and apparatus for forming a self-locking adjustable loop |
US20080140094A1 (en) * | 2006-12-11 | 2008-06-12 | Schwartz Herbert E | Unitary surgical device and method |
US7871440B2 (en) | 2006-12-11 | 2011-01-18 | Depuy Products, Inc. | Unitary surgical device and method |
US11612391B2 (en) * | 2007-01-16 | 2023-03-28 | Biomet Sports Medicine, Llc | Soft tissue repair device and associated methods |
US20200197002A1 (en) * | 2007-01-16 | 2020-06-25 | Biomet Sports Medicine, Llc | Soft tissue repair device and associated methods |
US9402668B2 (en) | 2007-02-13 | 2016-08-02 | P Tech, Llc | Tissue fixation system and method |
US20080208204A1 (en) * | 2007-02-13 | 2008-08-28 | Arthrex, Inc. | Intraarticular graft length gauge |
US20080195145A1 (en) * | 2007-02-13 | 2008-08-14 | Bonutti Peter M | Tissue fixation system and method |
EP1958591A3 (en) * | 2007-02-13 | 2009-09-23 | Arthrex, Inc. | Intraarticular graft length gauge |
US8617185B2 (en) | 2007-02-13 | 2013-12-31 | P Tech, Llc. | Fixation device |
US11801044B2 (en) | 2007-02-13 | 2023-10-31 | P Tech, Llc | Tissue fixation system and method |
US10517584B1 (en) | 2007-02-13 | 2019-12-31 | P Tech, Llc | Tissue fixation system and method |
US10390817B2 (en) | 2007-02-13 | 2019-08-27 | P Tech, Llc | Tissue fixation system and method |
US20080228198A1 (en) * | 2007-03-13 | 2008-09-18 | Mitralign, Inc. | Suture cutter and method of cutting suture |
US9358111B2 (en) | 2007-03-13 | 2016-06-07 | Mitralign, Inc. | Tissue anchors, systems and methods, and devices |
US8911461B2 (en) | 2007-03-13 | 2014-12-16 | Mitralign, Inc. | Suture cutter and method of cutting suture |
US11660190B2 (en) | 2007-03-13 | 2023-05-30 | Edwards Lifesciences Corporation | Tissue anchors, systems and methods, and devices |
US20100179577A1 (en) * | 2007-03-22 | 2010-07-15 | Ethicon Endo-Surgery, Inc. | Ultrasonic surgical instrument and cartilage and bone shaping blades therefor |
US20080234708A1 (en) * | 2007-03-22 | 2008-09-25 | Houser Kevin L | Surgical instruments |
US8236019B2 (en) | 2007-03-22 | 2012-08-07 | Ethicon Endo-Surgery, Inc. | Ultrasonic surgical instrument and cartilage and bone shaping blades therefor |
WO2008118707A3 (en) * | 2007-03-22 | 2009-01-15 | Ethicon Endo Surgery Inc | Surgical instruments |
US8226675B2 (en) | 2007-03-22 | 2012-07-24 | Ethicon Endo-Surgery, Inc. | Surgical instruments |
US10828057B2 (en) | 2007-03-22 | 2020-11-10 | Ethicon Llc | Ultrasonic surgical instruments |
US9504483B2 (en) | 2007-03-22 | 2016-11-29 | Ethicon Endo-Surgery, Llc | Surgical instruments |
US9987033B2 (en) | 2007-03-22 | 2018-06-05 | Ethicon Llc | Ultrasonic surgical instruments |
US20080234710A1 (en) * | 2007-03-22 | 2008-09-25 | Neurohr Mark A | Ultrasonic surgical instruments |
US20080234709A1 (en) * | 2007-03-22 | 2008-09-25 | Houser Kevin L | Ultrasonic surgical instrument and cartilage and bone shaping blades therefor |
US9883884B2 (en) | 2007-03-22 | 2018-02-06 | Ethicon Llc | Ultrasonic surgical instruments |
US9050124B2 (en) | 2007-03-22 | 2015-06-09 | Ethicon Endo-Surgery, Inc. | Ultrasonic surgical instrument and cartilage and bone shaping blades therefor |
US9801648B2 (en) | 2007-03-22 | 2017-10-31 | Ethicon Llc | Surgical instruments |
US10722261B2 (en) | 2007-03-22 | 2020-07-28 | Ethicon Llc | Surgical instruments |
US8142461B2 (en) | 2007-03-22 | 2012-03-27 | Ethicon Endo-Surgery, Inc. | Surgical instruments |
US8911460B2 (en) | 2007-03-22 | 2014-12-16 | Ethicon Endo-Surgery, Inc. | Ultrasonic surgical instruments |
US8900259B2 (en) | 2007-03-22 | 2014-12-02 | Ethicon Endo-Surgery, Inc. | Surgical instruments |
US9017381B2 (en) | 2007-04-10 | 2015-04-28 | Biomet Sports Medicine, Llc | Adjustable knotless loops |
US11185320B2 (en) | 2007-04-10 | 2021-11-30 | Biomet Sports Medicine, Llc | Adjustable knotless loops |
US10729423B2 (en) | 2007-04-10 | 2020-08-04 | Biomet Sports Medicine, Llc | Adjustable knotless loops |
US9861351B2 (en) | 2007-04-10 | 2018-01-09 | Biomet Sports Medicine, Llc | Adjustable knotless loops |
US9610070B2 (en) | 2007-06-15 | 2017-04-04 | Vivasure Medical Limited | Closure device |
US20090018574A1 (en) * | 2007-06-15 | 2009-01-15 | Zerusa Limited | Closure device |
US8808319B2 (en) | 2007-07-27 | 2014-08-19 | Ethicon Endo-Surgery, Inc. | Surgical instruments |
US9414853B2 (en) | 2007-07-27 | 2016-08-16 | Ethicon Endo-Surgery, Llc | Ultrasonic end effectors with increased active length |
US9220527B2 (en) | 2007-07-27 | 2015-12-29 | Ethicon Endo-Surgery, Llc | Surgical instruments |
US8523889B2 (en) | 2007-07-27 | 2013-09-03 | Ethicon Endo-Surgery, Inc. | Ultrasonic end effectors with increased active length |
US9913656B2 (en) | 2007-07-27 | 2018-03-13 | Ethicon Llc | Ultrasonic surgical instruments |
US8882791B2 (en) | 2007-07-27 | 2014-11-11 | Ethicon Endo-Surgery, Inc. | Ultrasonic surgical instruments |
US9707004B2 (en) | 2007-07-27 | 2017-07-18 | Ethicon Llc | Surgical instruments |
US9642644B2 (en) | 2007-07-27 | 2017-05-09 | Ethicon Endo-Surgery, Llc | Surgical instruments |
US10531910B2 (en) | 2007-07-27 | 2020-01-14 | Ethicon Llc | Surgical instruments |
US11607268B2 (en) | 2007-07-27 | 2023-03-21 | Cilag Gmbh International | Surgical instruments |
US20090030351A1 (en) * | 2007-07-27 | 2009-01-29 | Wiener Eitan T | Multiple end effectors ultrasonic surgical instruments |
US8652155B2 (en) | 2007-07-27 | 2014-02-18 | Ethicon Endo-Surgery, Inc. | Surgical instruments |
US10398466B2 (en) | 2007-07-27 | 2019-09-03 | Ethicon Llc | Ultrasonic end effectors with increased active length |
US20090030437A1 (en) * | 2007-07-27 | 2009-01-29 | Houser Kevin L | Surgical instruments |
US8348967B2 (en) | 2007-07-27 | 2013-01-08 | Ethicon Endo-Surgery, Inc. | Ultrasonic surgical instruments |
US20090030439A1 (en) * | 2007-07-27 | 2009-01-29 | Stulen Foster B | Ultrasonic surgical instruments |
US20090030311A1 (en) * | 2007-07-27 | 2009-01-29 | Stulen Foster B | Ultrasonic end effectors with increased active length |
US20090030438A1 (en) * | 2007-07-27 | 2009-01-29 | Stulen Foster B | Ultrasonic surgical instruments |
US8257377B2 (en) | 2007-07-27 | 2012-09-04 | Ethicon Endo-Surgery, Inc. | Multiple end effectors ultrasonic surgical instruments |
US11690641B2 (en) | 2007-07-27 | 2023-07-04 | Cilag Gmbh International | Ultrasonic end effectors with increased active length |
US9636135B2 (en) | 2007-07-27 | 2017-05-02 | Ethicon Endo-Surgery, Llc | Ultrasonic surgical instruments |
US8252012B2 (en) | 2007-07-31 | 2012-08-28 | Ethicon Endo-Surgery, Inc. | Ultrasonic surgical instrument with modulator |
US20090036911A1 (en) * | 2007-07-31 | 2009-02-05 | Stulen Foster B | Ultrasonic surgical instrument with modulator |
US9439669B2 (en) | 2007-07-31 | 2016-09-13 | Ethicon Endo-Surgery, Llc | Ultrasonic surgical instruments |
US9445832B2 (en) | 2007-07-31 | 2016-09-20 | Ethicon Endo-Surgery, Llc | Surgical instruments |
US20090036912A1 (en) * | 2007-07-31 | 2009-02-05 | Wiener Eitan T | Ultrasonic surgical instruments |
US10426507B2 (en) | 2007-07-31 | 2019-10-01 | Ethicon Llc | Ultrasonic surgical instruments |
US11058447B2 (en) | 2007-07-31 | 2021-07-13 | Cilag Gmbh International | Temperature controlled ultrasonic surgical instruments |
US8430898B2 (en) | 2007-07-31 | 2013-04-30 | Ethicon Endo-Surgery, Inc. | Ultrasonic surgical instruments |
US20090036913A1 (en) * | 2007-07-31 | 2009-02-05 | Eitan Wiener | Surgical instruments |
US20090036914A1 (en) * | 2007-07-31 | 2009-02-05 | Houser Kevin L | Temperature controlled ultrasonic surgical instruments |
US8512365B2 (en) | 2007-07-31 | 2013-08-20 | Ethicon Endo-Surgery, Inc. | Surgical instruments |
US11666784B2 (en) | 2007-07-31 | 2023-06-06 | Cilag Gmbh International | Surgical instruments |
US11877734B2 (en) | 2007-07-31 | 2024-01-23 | Cilag Gmbh International | Ultrasonic surgical instruments |
US9044261B2 (en) | 2007-07-31 | 2015-06-02 | Ethicon Endo-Surgery, Inc. | Temperature controlled ultrasonic surgical instruments |
US10420579B2 (en) | 2007-07-31 | 2019-09-24 | Ethicon Llc | Surgical instruments |
US8709031B2 (en) | 2007-07-31 | 2014-04-29 | Ethicon Endo-Surgery, Inc. | Methods for driving an ultrasonic surgical instrument with modulator |
US8771314B2 (en) | 2007-09-28 | 2014-07-08 | Ethicon, Inc. | Surgical anchor device |
US20090088797A1 (en) * | 2007-09-28 | 2009-04-02 | Ethicon, Inc. | Surgical anchor device |
USD631965S1 (en) | 2007-10-05 | 2011-02-01 | Ethicon Endo-Surgery, Inc. | Handle assembly for surgical instrument |
USD661803S1 (en) | 2007-10-05 | 2012-06-12 | Ethicon Endo-Surgery, Inc. | User interface for a surgical instrument |
US20090105750A1 (en) * | 2007-10-05 | 2009-04-23 | Ethicon Endo-Surgery, Inc. | Ergonomic surgical instruments |
US10828059B2 (en) | 2007-10-05 | 2020-11-10 | Ethicon Llc | Ergonomic surgical instruments |
US9848902B2 (en) | 2007-10-05 | 2017-12-26 | Ethicon Llc | Ergonomic surgical instruments |
US8623027B2 (en) | 2007-10-05 | 2014-01-07 | Ethicon Endo-Surgery, Inc. | Ergonomic surgical instruments |
USD661802S1 (en) | 2007-10-05 | 2012-06-12 | Ethicon Endo-Surgery, Inc. | User interface for a surgical instrument |
USD661804S1 (en) | 2007-10-05 | 2012-06-12 | Ethicon Endo-Surgery, Inc. | User interface for a surgical instrument |
USD618797S1 (en) | 2007-10-05 | 2010-06-29 | Ethicon Endo-Surgery, Inc. | Handle assembly for surgical instrument |
US9486236B2 (en) | 2007-10-05 | 2016-11-08 | Ethicon Endo-Surgery, Llc | Ergonomic surgical instruments |
USD661801S1 (en) | 2007-10-05 | 2012-06-12 | Ethicon Endo-Surgery, Inc. | User interface for a surgical instrument |
US20090112232A1 (en) * | 2007-10-31 | 2009-04-30 | Lawrence Crainich | Method for Deploying A Device For Gastric Volume Reduction |
US20090118762A1 (en) * | 2007-10-31 | 2009-05-07 | Lawrence Crainch | Disposable cartridge for use in a gastric volume reduction procedure |
US8496684B2 (en) | 2007-10-31 | 2013-07-30 | Ethicon Endo-Surgery, Inc. | Method for deploying a device for gastric volume reduction |
US20090138042A1 (en) * | 2007-11-07 | 2009-05-28 | Raymond Thal | Adjustable loop knotless anchor |
US8419769B2 (en) * | 2007-11-07 | 2013-04-16 | Raymond Thal | Adjustable loop knotless anchor |
US10433866B2 (en) | 2007-11-30 | 2019-10-08 | Ethicon Llc | Ultrasonic surgical blades |
US9066747B2 (en) | 2007-11-30 | 2015-06-30 | Ethicon Endo-Surgery, Inc. | Ultrasonic surgical instrument blades |
US10265094B2 (en) | 2007-11-30 | 2019-04-23 | Ethicon Llc | Ultrasonic surgical blades |
US10010339B2 (en) | 2007-11-30 | 2018-07-03 | Ethicon Llc | Ultrasonic surgical blades |
US10045794B2 (en) | 2007-11-30 | 2018-08-14 | Ethicon Llc | Ultrasonic surgical blades |
US9339289B2 (en) | 2007-11-30 | 2016-05-17 | Ehticon Endo-Surgery, LLC | Ultrasonic surgical instrument blades |
US11266433B2 (en) | 2007-11-30 | 2022-03-08 | Cilag Gmbh International | Ultrasonic surgical instrument blades |
US10888347B2 (en) | 2007-11-30 | 2021-01-12 | Ethicon Llc | Ultrasonic surgical blades |
US11766276B2 (en) | 2007-11-30 | 2023-09-26 | Cilag Gmbh International | Ultrasonic surgical blades |
US7901423B2 (en) | 2007-11-30 | 2011-03-08 | Ethicon Endo-Surgery, Inc. | Folded ultrasonic end effectors with increased active length |
US11253288B2 (en) | 2007-11-30 | 2022-02-22 | Cilag Gmbh International | Ultrasonic surgical instrument blades |
US8372102B2 (en) | 2007-11-30 | 2013-02-12 | Ethicon Endo-Surgery, Inc. | Folded ultrasonic end effectors with increased active length |
US20090143806A1 (en) * | 2007-11-30 | 2009-06-04 | Ethicon Endo-Surgery, Inc. | Ultrasonic surgical blades |
US11439426B2 (en) | 2007-11-30 | 2022-09-13 | Cilag Gmbh International | Ultrasonic surgical blades |
US10433865B2 (en) | 2007-11-30 | 2019-10-08 | Ethicon Llc | Ultrasonic surgical blades |
US8057498B2 (en) | 2007-11-30 | 2011-11-15 | Ethicon Endo-Surgery, Inc. | Ultrasonic surgical instrument blades |
US8182502B2 (en) | 2007-11-30 | 2012-05-22 | Ethicon Endo-Surgery, Inc. | Folded ultrasonic end effectors with increased active length |
US10245065B2 (en) | 2007-11-30 | 2019-04-02 | Ethicon Llc | Ultrasonic surgical blades |
US10441308B2 (en) | 2007-11-30 | 2019-10-15 | Ethicon Llc | Ultrasonic surgical instrument blades |
US20110125175A1 (en) * | 2007-11-30 | 2011-05-26 | Ethicon Endo-Surgery, Inc. | Folded ultrasonic end effectors with increased active length |
US11690643B2 (en) | 2007-11-30 | 2023-07-04 | Cilag Gmbh International | Ultrasonic surgical blades |
US8591536B2 (en) | 2007-11-30 | 2013-11-26 | Ethicon Endo-Surgery, Inc. | Ultrasonic surgical instrument blades |
US10463887B2 (en) | 2007-11-30 | 2019-11-05 | Ethicon Llc | Ultrasonic surgical blades |
US9826992B2 (en) | 2007-12-21 | 2017-11-28 | Smith & Nephew, Inc. | Multiple portal guide |
US9913636B2 (en) | 2007-12-21 | 2018-03-13 | Smith & Nephew, Inc. | Multiple portal guide |
EP2247252A2 (en) * | 2008-02-14 | 2010-11-10 | Robert C. Brown | Method for treating stress urinary incontinence and symptomatic pelvic relaxation |
EP2247252A4 (en) * | 2008-02-14 | 2015-01-28 | Robert C Brown | Method for treating stress urinary incontinence and symptomatic pelvic relaxation |
US8828054B2 (en) | 2008-04-02 | 2014-09-09 | Liavatec Corporation | Method and apparatus for meniscal repair |
US9386978B2 (en) | 2008-04-02 | 2016-07-12 | Linvatec Corporation | Method and apparatus for meniscal repair |
US20100049212A1 (en) * | 2008-04-02 | 2010-02-25 | David Caborn | Method and apparatus for meniscal repair |
US8828052B2 (en) | 2008-04-02 | 2014-09-09 | Linvatec Corporation | Method and apparatus for meniscal repair |
US20110071549A1 (en) * | 2008-04-02 | 2011-03-24 | David Caborn | Method and apparatus for meniscal repair |
US10478175B2 (en) | 2008-04-02 | 2019-11-19 | Linvatec Corporation | Method and apparatus for meniscal repair |
US9386982B2 (en) | 2008-04-02 | 2016-07-12 | Linvatec Corporation | Method and apparatus for meniscal repair |
US10022122B2 (en) * | 2008-06-06 | 2018-07-17 | DePuy Synthes Products, Inc. | Suture based tissue repair |
US20110077667A1 (en) * | 2008-06-06 | 2011-03-31 | Synthes Usa, Llc | Suture based tissue repair |
US8253303B2 (en) | 2008-08-06 | 2012-08-28 | Ethicon Endo-Surgery, Inc. | Ultrasonic device for cutting and coagulating with stepped output |
US8779648B2 (en) | 2008-08-06 | 2014-07-15 | Ethicon Endo-Surgery, Inc. | Ultrasonic device for cutting and coagulating with stepped output |
US8749116B2 (en) | 2008-08-06 | 2014-06-10 | Ethicon Endo-Surgery, Inc. | Devices and techniques for cutting and coagulating tissue |
US10335614B2 (en) | 2008-08-06 | 2019-07-02 | Ethicon Llc | Devices and techniques for cutting and coagulating tissue |
US9504855B2 (en) | 2008-08-06 | 2016-11-29 | Ethicon Surgery, LLC | Devices and techniques for cutting and coagulating tissue |
US11890491B2 (en) | 2008-08-06 | 2024-02-06 | Cilag Gmbh International | Devices and techniques for cutting and coagulating tissue |
US10022567B2 (en) | 2008-08-06 | 2018-07-17 | Ethicon Llc | Devices and techniques for cutting and coagulating tissue |
US10022568B2 (en) | 2008-08-06 | 2018-07-17 | Ethicon Llc | Devices and techniques for cutting and coagulating tissue |
US9072539B2 (en) | 2008-08-06 | 2015-07-07 | Ethicon Endo-Surgery, Inc. | Devices and techniques for cutting and coagulating tissue |
US9089360B2 (en) | 2008-08-06 | 2015-07-28 | Ethicon Endo-Surgery, Inc. | Devices and techniques for cutting and coagulating tissue |
US9795808B2 (en) | 2008-08-06 | 2017-10-24 | Ethicon Llc | Devices and techniques for cutting and coagulating tissue |
US8704425B2 (en) | 2008-08-06 | 2014-04-22 | Ethicon Endo-Surgery, Inc. | Ultrasonic device for cutting and coagulating with stepped output |
US8058771B2 (en) | 2008-08-06 | 2011-11-15 | Ethicon Endo-Surgery, Inc. | Ultrasonic device for cutting and coagulating with stepped output |
US8546996B2 (en) | 2008-08-06 | 2013-10-01 | Ethicon Endo-Surgery, Inc. | Devices and techniques for cutting and coagulating tissue |
US20110185560A1 (en) * | 2008-08-18 | 2011-08-04 | Qioptiq Photonics Gmbh & Co. Kg | Method for producing an objective |
US11534159B2 (en) | 2008-08-22 | 2022-12-27 | Biomet Sports Medicine, Llc | Method and apparatus for coupling soft tissue to a bone |
US8945211B2 (en) | 2008-09-12 | 2015-02-03 | Mitralign, Inc. | Tissue plication device and method for its use |
US9192372B2 (en) | 2008-10-14 | 2015-11-24 | Krt Investors, Inc. | Method for the treatment of tissue |
WO2010065829A1 (en) * | 2008-12-05 | 2010-06-10 | Wilson-Cook Medical, Inc. | Hood method and device for material dissection |
US20100145352A1 (en) * | 2008-12-05 | 2010-06-10 | Kenneth Chang | Hood method and device for endoscopic submucosal dissection |
US20100204731A1 (en) * | 2009-02-06 | 2010-08-12 | Rickey Hart | Suture Holding System |
US9662102B2 (en) | 2009-02-06 | 2017-05-30 | Karl Storz Gmbh & Co. Kg | Suture holding system |
US9445806B2 (en) | 2009-02-06 | 2016-09-20 | Karl Storz Gmbh & Co. Kg | Suture holder delivery system |
US9220493B2 (en) | 2009-02-06 | 2015-12-29 | Karl Storz Gmbh & Co. Kg | Suture anchor kit |
EP2215972A1 (en) * | 2009-02-06 | 2010-08-11 | Karl Storz GmbH & Co. KG | Suture holding system |
EP2215973A1 (en) * | 2009-02-06 | 2010-08-11 | Karl Storz GmbH & Co. KG | Suture holding system |
US9421086B2 (en) * | 2009-03-31 | 2016-08-23 | Arthrex, Inc. | Adjustable suture-button construct for knotless stabilization of cranial cruciate deficient ligament stifle |
US20140081399A1 (en) * | 2009-03-31 | 2014-03-20 | Arthrex, Inc. | Adjustable suture-button construct for knotless stabilization of cranial cruciate deficient ligament stifle |
US10285801B2 (en) * | 2009-03-31 | 2019-05-14 | Arthrex, Inc. | Adjustable suture-button construct for knotless stabilization of cranial cruciate deficient ligament stifle |
US20100298851A1 (en) * | 2009-05-20 | 2010-11-25 | Ethicon Endo-Surgery, Inc. | Coupling arrangements and methods for attaching tools to ultrasonic surgical instruments |
US20100298743A1 (en) * | 2009-05-20 | 2010-11-25 | Ethicon Endo-Surgery, Inc. | Thermally-activated coupling arrangements and methods for attaching tools to ultrasonic surgical instruments |
US9700339B2 (en) | 2009-05-20 | 2017-07-11 | Ethicon Endo-Surgery, Inc. | Coupling arrangements and methods for attaching tools to ultrasonic surgical instruments |
US10709906B2 (en) | 2009-05-20 | 2020-07-14 | Ethicon Llc | Coupling arrangements and methods for attaching tools to ultrasonic surgical instruments |
US10149767B2 (en) | 2009-05-28 | 2018-12-11 | Biomet Manufacturing, Llc | Method of implanting knee prosthesis assembly with ligament link |
US8343227B2 (en) | 2009-05-28 | 2013-01-01 | Biomet Manufacturing Corp. | Knee prosthesis assembly with ligament link |
US8900314B2 (en) | 2009-05-28 | 2014-12-02 | Biomet Manufacturing, Llc | Method of implanting a prosthetic knee joint assembly |
US8754570B2 (en) | 2009-06-24 | 2014-06-17 | Ethicon Endo-Surgery, Inc. | Ultrasonic surgical instruments comprising transducer arrangements |
US8319400B2 (en) | 2009-06-24 | 2012-11-27 | Ethicon Endo-Surgery, Inc. | Ultrasonic surgical instruments |
US9498245B2 (en) | 2009-06-24 | 2016-11-22 | Ethicon Endo-Surgery, Llc | Ultrasonic surgical instruments |
US8546999B2 (en) | 2009-06-24 | 2013-10-01 | Ethicon Endo-Surgery, Inc. | Housing arrangements for ultrasonic surgical instruments |
US8650728B2 (en) | 2009-06-24 | 2014-02-18 | Ethicon Endo-Surgery, Inc. | Method of assembling a transducer for a surgical instrument |
US8334635B2 (en) | 2009-06-24 | 2012-12-18 | Ethicon Endo-Surgery, Inc. | Transducer arrangements for ultrasonic surgical instruments |
US20100331870A1 (en) * | 2009-06-24 | 2010-12-30 | Ethicon Endo-Surgery, Inc. | Ultrasonic surgical instruments |
US8344596B2 (en) | 2009-06-24 | 2013-01-01 | Ethicon Endo-Surgery, Inc. | Transducer arrangements for ultrasonic surgical instruments |
US20110160856A1 (en) * | 2009-07-02 | 2011-06-30 | Medicinelodge, Inc. Dba Imds Co-Innovation | Systems and Methods for Zipknot ACL Fixation |
US20110015631A1 (en) * | 2009-07-15 | 2011-01-20 | Ethicon Endo-Surgery, Inc. | Electrosurgery generator for ultrasonic surgical instruments |
US20110015660A1 (en) * | 2009-07-15 | 2011-01-20 | Ethicon Endo-Surgery, Inc. | Rotating transducer mount for ultrasonic surgical instruments |
US8773001B2 (en) | 2009-07-15 | 2014-07-08 | Ethicon Endo-Surgery, Inc. | Rotating transducer mount for ultrasonic surgical instruments |
US9764164B2 (en) | 2009-07-15 | 2017-09-19 | Ethicon Llc | Ultrasonic surgical instruments |
US9017326B2 (en) | 2009-07-15 | 2015-04-28 | Ethicon Endo-Surgery, Inc. | Impedance monitoring apparatus, system, and method for ultrasonic surgical instruments |
US20110015627A1 (en) * | 2009-07-15 | 2011-01-20 | Ethicon Endo-Surgery, Inc. | Impedance monitoring apparatus, system, and method for ultrasonic surgical instruments |
US8663220B2 (en) | 2009-07-15 | 2014-03-04 | Ethicon Endo-Surgery, Inc. | Ultrasonic surgical instruments |
US10688321B2 (en) | 2009-07-15 | 2020-06-23 | Ethicon Llc | Ultrasonic surgical instruments |
US8461744B2 (en) | 2009-07-15 | 2013-06-11 | Ethicon Endo-Surgery, Inc. | Rotating transducer mount for ultrasonic surgical instruments |
US11717706B2 (en) | 2009-07-15 | 2023-08-08 | Cilag Gmbh International | Ultrasonic surgical instruments |
US20110022061A1 (en) * | 2009-07-24 | 2011-01-27 | Depuy Mitek, Inc. | Apparatus and method for repairing tissue |
US11071537B2 (en) | 2009-07-24 | 2021-07-27 | DePuy Synthes Products, Inc. | Apparatus and method for repairing tissue |
US10149675B2 (en) | 2009-07-24 | 2018-12-11 | Depuy Mitek, Llc | Apparatus and method for repairing tissue |
US9421012B2 (en) | 2009-07-24 | 2016-08-23 | Depuy Mitek, Llc | Apparatus and method for repairing tissue |
US8790369B2 (en) | 2009-07-24 | 2014-07-29 | Depuy Mitek, Llc | Apparatus and method for repairing tissue |
US10172669B2 (en) | 2009-10-09 | 2019-01-08 | Ethicon Llc | Surgical instrument comprising an energy trigger lockout |
US20110087212A1 (en) * | 2009-10-09 | 2011-04-14 | Ethicon Endo-Surgery, Inc. | Surgical generator for ultrasonic and electrosurgical devices |
US20110087215A1 (en) * | 2009-10-09 | 2011-04-14 | Ethicon Endo-Surgery, Inc. | Surgical generator for ultrasonic and electrosurgical devices |
US10263171B2 (en) | 2009-10-09 | 2019-04-16 | Ethicon Llc | Surgical generator for ultrasonic and electrosurgical devices |
US8956349B2 (en) | 2009-10-09 | 2015-02-17 | Ethicon Endo-Surgery, Inc. | Surgical generator for ultrasonic and electrosurgical devices |
US9060775B2 (en) | 2009-10-09 | 2015-06-23 | Ethicon Endo-Surgery, Inc. | Surgical generator for ultrasonic and electrosurgical devices |
US9060776B2 (en) | 2009-10-09 | 2015-06-23 | Ethicon Endo-Surgery, Inc. | Surgical generator for ultrasonic and electrosurgical devices |
US20110087256A1 (en) * | 2009-10-09 | 2011-04-14 | Ethicon Endo-Surgery, Inc. | Surgical generator for ultrasonic and electrosurgical devices |
US10265117B2 (en) | 2009-10-09 | 2019-04-23 | Ethicon Llc | Surgical generator method for controlling and ultrasonic transducer waveform for ultrasonic and electrosurgical devices |
US10441345B2 (en) | 2009-10-09 | 2019-10-15 | Ethicon Llc | Surgical generator for ultrasonic and electrosurgical devices |
US9623237B2 (en) | 2009-10-09 | 2017-04-18 | Ethicon Endo-Surgery, Llc | Surgical generator for ultrasonic and electrosurgical devices |
USRE47996E1 (en) | 2009-10-09 | 2020-05-19 | Ethicon Llc | Surgical generator for ultrasonic and electrosurgical devices |
US9050093B2 (en) | 2009-10-09 | 2015-06-09 | Ethicon Endo-Surgery, Inc. | Surgical generator for ultrasonic and electrosurgical devices |
US9168054B2 (en) | 2009-10-09 | 2015-10-27 | Ethicon Endo-Surgery, Inc. | Surgical generator for ultrasonic and electrosurgical devices |
US9039695B2 (en) | 2009-10-09 | 2015-05-26 | Ethicon Endo-Surgery, Inc. | Surgical generator for ultrasonic and electrosurgical devices |
US11090104B2 (en) | 2009-10-09 | 2021-08-17 | Cilag Gmbh International | Surgical generator for ultrasonic and electrosurgical devices |
US20110087214A1 (en) * | 2009-10-09 | 2011-04-14 | Ethicon Endo-Surgery, Inc. | Surgical generator for ultrasonic and electrosurgical devices |
US10201382B2 (en) | 2009-10-09 | 2019-02-12 | Ethicon Llc | Surgical generator for ultrasonic and electrosurgical devices |
US8951248B2 (en) | 2009-10-09 | 2015-02-10 | Ethicon Endo-Surgery, Inc. | Surgical generator for ultrasonic and electrosurgical devices |
US8986302B2 (en) | 2009-10-09 | 2015-03-24 | Ethicon Endo-Surgery, Inc. | Surgical generator for ultrasonic and electrosurgical devices |
US11871982B2 (en) | 2009-10-09 | 2024-01-16 | Cilag Gmbh International | Surgical generator for ultrasonic and electrosurgical devices |
US11744575B2 (en) * | 2009-11-09 | 2023-09-05 | Ceterix Orthopaedics, Inc. | Suture passer devices and methods |
US11357486B2 (en) | 2009-12-30 | 2022-06-14 | Vivasure Medical Limited | Closure system and uses thereof |
US8486096B2 (en) | 2010-02-11 | 2013-07-16 | Ethicon Endo-Surgery, Inc. | Dual purpose surgical instrument for cutting and coagulating tissue |
US20110196401A1 (en) * | 2010-02-11 | 2011-08-11 | Ethicon Endo-Surgery, Inc. | Ultrasonic surgical instruments with partially rotating blade and fixed pad arrangement |
US11369402B2 (en) | 2010-02-11 | 2022-06-28 | Cilag Gmbh International | Control systems for ultrasonically powered surgical instruments |
US9107689B2 (en) | 2010-02-11 | 2015-08-18 | Ethicon Endo-Surgery, Inc. | Dual purpose surgical instrument for cutting and coagulating tissue |
US9510850B2 (en) | 2010-02-11 | 2016-12-06 | Ethicon Endo-Surgery, Llc | Ultrasonic surgical instruments |
US8531064B2 (en) | 2010-02-11 | 2013-09-10 | Ethicon Endo-Surgery, Inc. | Ultrasonically powered surgical instruments with rotating cutting implement |
US10299810B2 (en) | 2010-02-11 | 2019-05-28 | Ethicon Llc | Rotatable cutting implements with friction reducing material for ultrasonic surgical instruments |
US20110196402A1 (en) * | 2010-02-11 | 2011-08-11 | Ethicon Endo-Surgery, Inc. | Dual purpose surgical instrument for cutting and coagulating tissue |
US8579928B2 (en) | 2010-02-11 | 2013-11-12 | Ethicon Endo-Surgery, Inc. | Outer sheath and blade arrangements for ultrasonic surgical instruments |
US9848901B2 (en) | 2010-02-11 | 2017-12-26 | Ethicon Llc | Dual purpose surgical instrument for cutting and coagulating tissue |
US8951272B2 (en) | 2010-02-11 | 2015-02-10 | Ethicon Endo-Surgery, Inc. | Seal arrangements for ultrasonically powered surgical instruments |
US8419759B2 (en) | 2010-02-11 | 2013-04-16 | Ethicon Endo-Surgery, Inc. | Ultrasonic surgical instrument with comb-like tissue trimming device |
US20110196404A1 (en) * | 2010-02-11 | 2011-08-11 | Ethicon Endo-Surgery, Inc. | Ultrasonic surgical instruments with moving cutting implement |
US20110196405A1 (en) * | 2010-02-11 | 2011-08-11 | Ethicon Endo-Surgery, Inc. | Ultrasonic surgical instrument with comb-like tissue trimming device |
US11382642B2 (en) | 2010-02-11 | 2022-07-12 | Cilag Gmbh International | Rotatable cutting implements with friction reducing material for ultrasonic surgical instruments |
US10117667B2 (en) | 2010-02-11 | 2018-11-06 | Ethicon Llc | Control systems for ultrasonically powered surgical instruments |
US9962182B2 (en) | 2010-02-11 | 2018-05-08 | Ethicon Llc | Ultrasonic surgical instruments with moving cutting implement |
US9427249B2 (en) | 2010-02-11 | 2016-08-30 | Ethicon Endo-Surgery, Llc | Rotatable cutting implements with friction reducing material for ultrasonic surgical instruments |
US20110196286A1 (en) * | 2010-02-11 | 2011-08-11 | Ethicon Endo-Surgery, Inc. | Ultrasonically powered surgical instruments with rotating cutting implement |
US8323302B2 (en) | 2010-02-11 | 2012-12-04 | Ethicon Endo-Surgery, Inc. | Methods of using ultrasonically powered surgical instruments with rotatable cutting implements |
US20110196287A1 (en) * | 2010-02-11 | 2011-08-11 | Ethicon Endo-Surgery, Inc. | Methods of using ultrasonically powered surgical instruments with rotatable cutting implements |
US8961547B2 (en) | 2010-02-11 | 2015-02-24 | Ethicon Endo-Surgery, Inc. | Ultrasonic surgical instruments with moving cutting implement |
US8382782B2 (en) | 2010-02-11 | 2013-02-26 | Ethicon Endo-Surgery, Inc. | Ultrasonic surgical instruments with partially rotating blade and fixed pad arrangement |
US10835768B2 (en) | 2010-02-11 | 2020-11-17 | Ethicon Llc | Dual purpose surgical instrument for cutting and coagulating tissue |
US9259234B2 (en) | 2010-02-11 | 2016-02-16 | Ethicon Endo-Surgery, Llc | Ultrasonic surgical instruments with rotatable blade and hollow sheath arrangements |
US8469981B2 (en) | 2010-02-11 | 2013-06-25 | Ethicon Endo-Surgery, Inc. | Rotatable cutting implement arrangements for ultrasonic surgical instruments |
US9649126B2 (en) | 2010-02-11 | 2017-05-16 | Ethicon Endo-Surgery, Llc | Seal arrangements for ultrasonically powered surgical instruments |
US11090103B2 (en) | 2010-05-21 | 2021-08-17 | Cilag Gmbh International | Medical device |
US9707027B2 (en) | 2010-05-21 | 2017-07-18 | Ethicon Endo-Surgery, Llc | Medical device |
US10335139B2 (en) | 2010-06-09 | 2019-07-02 | C.R. Bard, Inc. | Instruments for delivering transfascial sutures, transfascial suture assemblies, and methods of transfascial suturing |
US9439643B2 (en) | 2010-06-09 | 2016-09-13 | C.R. Bard, Inc. | Instruments for delivering transfascial sutures, transfascial suture assemblies, and methods of transfascial suturing |
US8790356B2 (en) | 2010-06-09 | 2014-07-29 | C.R. Bard, Inc. | Instruments for delivering transfascial sutures, transfascial suture assemblies, and methods of transfascial suturing |
US10492777B2 (en) | 2010-06-09 | 2019-12-03 | C.R. Bard, Inc. | Instruments for delivering transfascial sutures, transfascial suture assemblies, and methods of transfascial suturing |
US9393007B2 (en) | 2010-06-09 | 2016-07-19 | C.R. Bard, Inc. | Instruments for delivering transfascial sutures, transfascial assemblies, and methods of transfascial suturing |
US10278721B2 (en) | 2010-07-22 | 2019-05-07 | Ethicon Llc | Electrosurgical instrument with separate closure and cutting members |
US10524854B2 (en) | 2010-07-23 | 2020-01-07 | Ethicon Llc | Surgical instrument |
US9888936B2 (en) | 2010-09-27 | 2018-02-13 | Smith & Nephew, Inc. | Device and methods for use during arthroscopic surgery |
US8888809B2 (en) | 2010-10-01 | 2014-11-18 | Ethicon Endo-Surgery, Inc. | Surgical instrument with jaw member |
US8979890B2 (en) | 2010-10-01 | 2015-03-17 | Ethicon Endo-Surgery, Inc. | Surgical instrument with jaw member |
US9707030B2 (en) | 2010-10-01 | 2017-07-18 | Ethicon Endo-Surgery, Llc | Surgical instrument with jaw member |
US10219812B2 (en) | 2010-11-03 | 2019-03-05 | Smith & Nephew, Inc. | Drill guide |
US9345468B2 (en) | 2010-11-23 | 2016-05-24 | Medos International Sárl | Surgical filament snare assemblies |
US8814905B2 (en) | 2010-11-23 | 2014-08-26 | Depuy Mitek, Llc | Surgical filament snare assemblies |
US11039827B2 (en) | 2010-11-23 | 2021-06-22 | Medos International Sàrl | Surgical filament snare assemblies |
US9179908B2 (en) | 2010-11-23 | 2015-11-10 | Medos International Sàrl | Surgical filament snare assemblies |
US8821545B2 (en) | 2010-11-23 | 2014-09-02 | Depuy Mitek, Llc | Surgical filament snare assemblies |
US8821544B2 (en) | 2010-11-23 | 2014-09-02 | Depuy Mitek, Llc | Surgical filament snare assemblies |
US10292695B2 (en) | 2010-11-23 | 2019-05-21 | Medos International Sàrl | Surgical filament snare assemblies |
US9532778B2 (en) | 2010-11-23 | 2017-01-03 | Medos International Sàrl | Surgical filament snare assemblies |
US9895145B2 (en) | 2010-11-23 | 2018-02-20 | Medos International Sàrl | Surgical filament snare assemblies |
US9198653B2 (en) | 2010-11-23 | 2015-12-01 | Medos International Sàrl | Surgical filament snare assemblies |
US10912549B2 (en) | 2010-11-23 | 2021-02-09 | Medos International Sàrl | Surgical filament snare assemblies |
US9833229B2 (en) | 2010-12-23 | 2017-12-05 | Medos International Sàrl | Adjustable anchor systems and methods |
US10835231B2 (en) | 2010-12-23 | 2020-11-17 | Medos International Sàrl | Adjustable anchor systems and methods |
US8974495B2 (en) | 2010-12-23 | 2015-03-10 | Medos International Sàrl | Adjustable anchor systems and methods |
US8821543B2 (en) | 2010-12-23 | 2014-09-02 | Depuy Mitek, Llc | Adjustable anchor systems and methods |
US9095331B2 (en) | 2010-12-23 | 2015-08-04 | Medos International Sàrl | Adjustable anchor systems and methods |
US9060751B2 (en) | 2010-12-30 | 2015-06-23 | Vivasure Medical Limited | Surgical closure systems and methods |
US9962212B2 (en) | 2011-01-06 | 2018-05-08 | Smith & Nephew, Inc. | Cannulated guide tools |
US9125707B2 (en) | 2011-01-06 | 2015-09-08 | Smith & Nephew, Inc. | Cannulated guide tools |
US9918775B2 (en) | 2011-04-12 | 2018-03-20 | Covidien Lp | Systems and methods for calibrating power measurements in an electrosurgical generator |
US9301760B2 (en) | 2011-05-03 | 2016-04-05 | Dermaclip Us, Llc | Devices for securely closing tissue openings with minimized scarring |
US9216078B2 (en) | 2011-05-17 | 2015-12-22 | Biomet Sports Medicine, Llc | Method and apparatus for tibial fixation of an ACL graft |
US8771352B2 (en) | 2011-05-17 | 2014-07-08 | Biomet Sports Medicine, Llc | Method and apparatus for tibial fixation of an ACL graft |
US9198648B2 (en) | 2011-06-20 | 2015-12-01 | Ethicon, Inc. | Method and device for approximating tissue |
CN103607963A (en) * | 2011-06-20 | 2014-02-26 | 伊西康公司 | Method and device for approximating tissue |
US20130178898A1 (en) * | 2011-07-06 | 2013-07-11 | Imds Corporation | Tissue approximation |
EP2548519B1 (en) | 2011-07-21 | 2015-09-16 | Arthrex, Inc. | Knotless suture constructs |
EP2548519B2 (en) † | 2011-07-21 | 2019-07-24 | Arthrex, Inc. | Knotless suture constructs |
US10433900B2 (en) | 2011-07-22 | 2019-10-08 | Ethicon Llc | Surgical instruments for tensioning tissue |
USD700966S1 (en) | 2011-08-23 | 2014-03-11 | Covidien Ag | Portable surgical device |
USD691265S1 (en) | 2011-08-23 | 2013-10-08 | Covidien Ag | Control assembly for portable surgical device |
USD700699S1 (en) | 2011-08-23 | 2014-03-04 | Covidien Ag | Handle for portable surgical device |
USD700967S1 (en) | 2011-08-23 | 2014-03-11 | Covidien Ag | Handle for portable surgical device |
USD687549S1 (en) | 2011-10-24 | 2013-08-06 | Ethicon Endo-Surgery, Inc. | Surgical instrument |
US9826972B2 (en) | 2011-10-24 | 2017-11-28 | C.R. Bard, Inc. | Instruments for delivering transfascial sutures, transfascial suture assemblies and methods of transfascial suturing |
US10779876B2 (en) | 2011-10-24 | 2020-09-22 | Ethicon Llc | Battery powered surgical instrument |
WO2013062933A1 (en) * | 2011-10-24 | 2013-05-02 | C.R. Bard, Inc. | Instruments for delivering transfascial sutures, transfascial suture assemblies and methods of transfascial suturing |
US8506597B2 (en) | 2011-10-25 | 2013-08-13 | Biomet Sports Medicine, Llc | Method and apparatus for interosseous membrane reconstruction |
US9445827B2 (en) | 2011-10-25 | 2016-09-20 | Biomet Sports Medicine, Llc | Method and apparatus for intraosseous membrane reconstruction |
US11241305B2 (en) | 2011-11-03 | 2022-02-08 | Biomet Sports Medicine, Llc | Method and apparatus for stitching tendons |
US10265159B2 (en) | 2011-11-03 | 2019-04-23 | Biomet Sports Medicine, Llc | Method and apparatus for stitching tendons |
US9357991B2 (en) | 2011-11-03 | 2016-06-07 | Biomet Sports Medicine, Llc | Method and apparatus for stitching tendons |
US11317905B2 (en) | 2011-11-07 | 2022-05-03 | C.R. Bard, Inc. | Instruments for delivering transfascial sutures and methods of transfascial suturing |
US9039721B2 (en) | 2011-11-07 | 2015-05-26 | C.R. Bard, Inc. | Instruments for delivering transfascial sutures and methods of transfascial suturing |
US9078648B2 (en) | 2011-11-07 | 2015-07-14 | C.R. Bard, Inc. | Instruments for delivering transfascial sutures and methods of transfascial suturing |
US9924938B2 (en) | 2011-11-07 | 2018-03-27 | C.R. Bard, Inc. | Instruments for delivering transfascial sutures and methods of transfascial suturing |
US11534157B2 (en) | 2011-11-10 | 2022-12-27 | Biomet Sports Medicine, Llc | Method for coupling soft tissue to a bone |
US9381013B2 (en) | 2011-11-10 | 2016-07-05 | Biomet Sports Medicine, Llc | Method for coupling soft tissue to a bone |
US9370350B2 (en) | 2011-11-10 | 2016-06-21 | Biomet Sports Medicine, Llc | Apparatus for coupling soft tissue to a bone |
US9357992B2 (en) | 2011-11-10 | 2016-06-07 | Biomet Sports Medicine, Llc | Method for coupling soft tissue to a bone |
US9314241B2 (en) | 2011-11-10 | 2016-04-19 | Biomet Sports Medicine, Llc | Apparatus for coupling soft tissue to a bone |
US10363028B2 (en) | 2011-11-10 | 2019-07-30 | Biomet Sports Medicine, Llc | Method for coupling soft tissue to a bone |
US10368856B2 (en) | 2011-11-10 | 2019-08-06 | Biomet Sports Medicine, Llc | Apparatus for coupling soft tissue to a bone |
US9259217B2 (en) | 2012-01-03 | 2016-02-16 | Biomet Manufacturing, Llc | Suture Button |
US9433407B2 (en) | 2012-01-03 | 2016-09-06 | Biomet Manufacturing, Llc | Method of implanting a bone fixation assembly |
US10729494B2 (en) | 2012-02-10 | 2020-08-04 | Ethicon Llc | Robotically controlled surgical instrument |
US9925003B2 (en) | 2012-02-10 | 2018-03-27 | Ethicon Endo-Surgery, Llc | Robotically controlled surgical instrument |
US9232979B2 (en) | 2012-02-10 | 2016-01-12 | Ethicon Endo-Surgery, Inc. | Robotically controlled surgical instrument |
US9572558B2 (en) | 2012-02-29 | 2017-02-21 | Vivasure Medical Limited | Devices and methods for delivering implants for percutaneous perforation closure |
US9662099B2 (en) | 2012-02-29 | 2017-05-30 | Vivasure Medical Limited | Percutaneous perforation closure systems, devices, and methods |
US11957328B2 (en) | 2012-02-29 | 2024-04-16 | Vivasure Medical Limited | Implants and methods for percutaneous perforation closure |
US9737286B2 (en) | 2012-02-29 | 2017-08-22 | Vivasure Medical Limited | Implants and methods for percutaneous perforation closure |
US10966698B2 (en) | 2012-02-29 | 2021-04-06 | Vivasure Medical Limited | Implants and methods for percutaneous perforation closure |
US10751041B2 (en) | 2012-03-30 | 2020-08-25 | Medos International Sarl | Surgical filament assemblies |
US11771414B2 (en) | 2012-03-30 | 2023-10-03 | Medos International Sarl | Surgical filament assemblies |
US9872678B2 (en) | 2012-03-30 | 2018-01-23 | Medos International Sarl | Surgical filament assemblies |
US8790370B2 (en) | 2012-03-30 | 2014-07-29 | Depuy Mitek, Llc | Surgical filament assemblies |
US9700343B2 (en) | 2012-04-09 | 2017-07-11 | Ethicon Endo-Surgery, Llc | Devices and techniques for cutting and coagulating tissue |
US9241731B2 (en) | 2012-04-09 | 2016-01-26 | Ethicon Endo-Surgery, Inc. | Rotatable electrical connection for ultrasonic surgical instruments |
US9237921B2 (en) | 2012-04-09 | 2016-01-19 | Ethicon Endo-Surgery, Inc. | Devices and techniques for cutting and coagulating tissue |
US9439668B2 (en) | 2012-04-09 | 2016-09-13 | Ethicon Endo-Surgery, Llc | Switch arrangements for ultrasonic surgical instruments |
US10517627B2 (en) | 2012-04-09 | 2019-12-31 | Ethicon Llc | Switch arrangements for ultrasonic surgical instruments |
US9226766B2 (en) | 2012-04-09 | 2016-01-05 | Ethicon Endo-Surgery, Inc. | Serial communication protocol for medical device |
US9724118B2 (en) | 2012-04-09 | 2017-08-08 | Ethicon Endo-Surgery, Llc | Techniques for cutting and coagulating tissue for ultrasonic surgical instruments |
US11419626B2 (en) | 2012-04-09 | 2022-08-23 | Cilag Gmbh International | Switch arrangements for ultrasonic surgical instruments |
US9265514B2 (en) | 2012-04-17 | 2016-02-23 | Miteas Ltd. | Manipulator for grasping tissue |
US11633203B2 (en) | 2012-04-17 | 2023-04-25 | A-Base Korlatolt Felelossegu Tarsasag | Manipulator for grasping tissue |
US10441302B2 (en) | 2012-04-17 | 2019-10-15 | A-Base Korlatolt Felelossegu Tarsasag | Manipulator for grasping tissue |
US9610088B2 (en) | 2012-04-17 | 2017-04-04 | A-Base Korlatolt Felelossegu Tarsasag | Manipulator for grasping tissue |
US9034013B2 (en) | 2012-05-07 | 2015-05-19 | Medos International Sàrl | Systems, devices, and methods for securing tissue using a suture having one or more protrusions |
US10524777B2 (en) | 2012-05-07 | 2020-01-07 | Medos International Sàrl | Systems, devices, and methods for securing tissue |
US10271833B2 (en) | 2012-05-07 | 2019-04-30 | Medos International Sàrl | Systems, devices, and methods for securing tissue using snare assemblies and soft anchors |
US9060764B2 (en) | 2012-05-07 | 2015-06-23 | Medos International Sàrl | Systems, devices, and methods for securing tissue |
US9060763B2 (en) | 2012-05-07 | 2015-06-23 | Medos International Sàrl | Systems, devices, and methods for securing tissue |
US8894684B2 (en) | 2012-05-07 | 2014-11-25 | Medos International Sàrl | Systems, devices, and methods for securing tissue using a suture having one or more protrusions |
US11272915B2 (en) | 2012-05-07 | 2022-03-15 | Medos International Sarl | Systems, devices, and methods for securing tissue using snare assemblies and soft anchors |
US9757116B2 (en) | 2012-05-07 | 2017-09-12 | Medos International Sárl | Systems, devices, and methods for securing tissue |
US11564676B2 (en) | 2012-05-07 | 2023-01-31 | Medos International Sarl | Systems, devices, and methods for securing tissue |
US9345567B2 (en) | 2012-05-07 | 2016-05-24 | Medos International Sàrl | Systems, devices, and methods for securing tissue using snare assemblies and soft anchors |
US9795373B2 (en) | 2012-05-07 | 2017-10-24 | Medos International Sàrl | Systems, devices, and methods for securing tissue using a suture having one or more protrusions |
US10987123B2 (en) | 2012-06-28 | 2021-04-27 | Ethicon Llc | Surgical instruments with articulating shafts |
US9326788B2 (en) | 2012-06-29 | 2016-05-03 | Ethicon Endo-Surgery, Llc | Lockout mechanism for use with robotic electrosurgical device |
US9198714B2 (en) | 2012-06-29 | 2015-12-01 | Ethicon Endo-Surgery, Inc. | Haptic feedback devices for surgical robot |
US10543008B2 (en) | 2012-06-29 | 2020-01-28 | Ethicon Llc | Ultrasonic surgical instruments with distally positioned jaw assemblies |
US11871955B2 (en) | 2012-06-29 | 2024-01-16 | Cilag Gmbh International | Surgical instruments with articulating shafts |
US10524872B2 (en) | 2012-06-29 | 2020-01-07 | Ethicon Llc | Closed feedback control for electrosurgical device |
US9226767B2 (en) | 2012-06-29 | 2016-01-05 | Ethicon Endo-Surgery, Inc. | Closed feedback control for electrosurgical device |
US9351754B2 (en) | 2012-06-29 | 2016-05-31 | Ethicon Endo-Surgery, Llc | Ultrasonic surgical instruments with distally positioned jaw assemblies |
US11096752B2 (en) | 2012-06-29 | 2021-08-24 | Cilag Gmbh International | Closed feedback control for electrosurgical device |
US10966747B2 (en) | 2012-06-29 | 2021-04-06 | Ethicon Llc | Haptic feedback devices for surgical robot |
US10993763B2 (en) | 2012-06-29 | 2021-05-04 | Ethicon Llc | Lockout mechanism for use with robotic electrosurgical device |
US9713507B2 (en) | 2012-06-29 | 2017-07-25 | Ethicon Endo-Surgery, Llc | Closed feedback control for electrosurgical device |
US10779845B2 (en) | 2012-06-29 | 2020-09-22 | Ethicon Llc | Ultrasonic surgical instruments with distally positioned transducers |
US11426191B2 (en) | 2012-06-29 | 2022-08-30 | Cilag Gmbh International | Ultrasonic surgical instruments with distally positioned jaw assemblies |
US10441310B2 (en) | 2012-06-29 | 2019-10-15 | Ethicon Llc | Surgical instruments with curved section |
US9393037B2 (en) | 2012-06-29 | 2016-07-19 | Ethicon Endo-Surgery, Llc | Surgical instruments with articulating shafts |
US10398497B2 (en) | 2012-06-29 | 2019-09-03 | Ethicon Llc | Lockout mechanism for use with robotic electrosurgical device |
US10335183B2 (en) | 2012-06-29 | 2019-07-02 | Ethicon Llc | Feedback devices for surgical control systems |
US9820768B2 (en) | 2012-06-29 | 2017-11-21 | Ethicon Llc | Ultrasonic surgical instruments with control mechanisms |
US11583306B2 (en) | 2012-06-29 | 2023-02-21 | Cilag Gmbh International | Surgical instruments with articulating shafts |
US9408622B2 (en) | 2012-06-29 | 2016-08-09 | Ethicon Endo-Surgery, Llc | Surgical instruments with articulating shafts |
US9283045B2 (en) | 2012-06-29 | 2016-03-15 | Ethicon Endo-Surgery, Llc | Surgical instruments with fluid management system |
US10842580B2 (en) | 2012-06-29 | 2020-11-24 | Ethicon Llc | Ultrasonic surgical instruments with control mechanisms |
US11602371B2 (en) | 2012-06-29 | 2023-03-14 | Cilag Gmbh International | Ultrasonic surgical instruments with control mechanisms |
US9737326B2 (en) | 2012-06-29 | 2017-08-22 | Ethicon Endo-Surgery, Llc | Haptic feedback devices for surgical robot |
US10335182B2 (en) | 2012-06-29 | 2019-07-02 | Ethicon Llc | Surgical instruments with articulating shafts |
US11717311B2 (en) | 2012-06-29 | 2023-08-08 | Cilag Gmbh International | Surgical instruments with articulating shafts |
US9763655B2 (en) | 2012-09-20 | 2017-09-19 | Medos International Sarl | Systems, devices, and methods for securing tissue using hard anchors |
US11672523B2 (en) | 2012-09-20 | 2023-06-13 | Medos International Sarl | Systems, devices, and methods for securing tissue using hard anchors |
US10695047B2 (en) | 2012-09-20 | 2020-06-30 | Medos International Sarl | Systems, devices, and methods for securing tissue using hard anchors |
US9517060B2 (en) | 2012-09-27 | 2016-12-13 | Ethicon, Inc. | Method and device for approximating tissue |
US10881449B2 (en) | 2012-09-28 | 2021-01-05 | Ethicon Llc | Multi-function bi-polar forceps |
US11179173B2 (en) | 2012-10-22 | 2021-11-23 | Cilag Gmbh International | Surgical instrument |
US9795405B2 (en) | 2012-10-22 | 2017-10-24 | Ethicon Llc | Surgical instrument |
US10201365B2 (en) | 2012-10-22 | 2019-02-12 | Ethicon Llc | Surgeon feedback sensing and display methods |
US9095367B2 (en) | 2012-10-22 | 2015-08-04 | Ethicon Endo-Surgery, Inc. | Flexible harmonic waveguides/blades for surgical instruments |
US10786235B2 (en) | 2012-10-31 | 2020-09-29 | Anchor Innovation Medical, Inc. | Method and apparatus for closing a fissure in the annulus of an intervertebral disc, and/or for effecting other anatomical repairs and/or fixations |
US9949734B2 (en) | 2012-10-31 | 2018-04-24 | Suture Concepts Inc. | Method and apparatus for closing a fissure in the annulus of an intervertebral disc, and/or for effecting other anatomical repairs and/or fixations |
US10863979B2 (en) | 2012-10-31 | 2020-12-15 | Anchor Innovation Medical, Inc. | Method and apparatus for closing a fissure in the annulus of an intervertebral disc, and/or for effecting other anatomical repairs and/or fixations |
US11324527B2 (en) | 2012-11-15 | 2022-05-10 | Cilag Gmbh International | Ultrasonic and electrosurgical devices |
US9192373B2 (en) | 2012-12-27 | 2015-11-24 | Medos International Sàrl | Surgical constructs and methods for securing tissue |
US9271716B2 (en) | 2012-12-27 | 2016-03-01 | Medos International Sàrl | Surgical constructs and methods for securing tissue |
US11369361B2 (en) | 2012-12-27 | 2022-06-28 | Medos International Sarl | Surgical constructs and methods for securing tissue |
US10258321B2 (en) | 2012-12-27 | 2019-04-16 | Medos International Sàrl | Surgical constructs and methods for securing tissue |
US10076377B2 (en) | 2013-01-05 | 2018-09-18 | P Tech, Llc | Fixation systems and methods |
US9757119B2 (en) | 2013-03-08 | 2017-09-12 | Biomet Sports Medicine, Llc | Visual aid for identifying suture limbs arthroscopically |
US10758221B2 (en) | 2013-03-14 | 2020-09-01 | Biomet Sports Medicine, Llc | Scaffold for spring ligament repair |
US9918827B2 (en) | 2013-03-14 | 2018-03-20 | Biomet Sports Medicine, Llc | Scaffold for spring ligament repair |
US11272952B2 (en) | 2013-03-14 | 2022-03-15 | Cilag Gmbh International | Mechanical fasteners for use with surgical energy devices |
US10226273B2 (en) | 2013-03-14 | 2019-03-12 | Ethicon Llc | Mechanical fasteners for use with surgical energy devices |
US9241728B2 (en) | 2013-03-15 | 2016-01-26 | Ethicon Endo-Surgery, Inc. | Surgical instrument with multiple clamping mechanisms |
US9850013B2 (en) | 2013-03-15 | 2017-12-26 | Vivasure Medical Limited | Loading devices and methods for percutaneous perforation closure systems |
US10631848B2 (en) | 2013-03-15 | 2020-04-28 | Medos International Sàrl | Surgical constructs with collapsing suture loop and methods for securing tissue |
US9737293B2 (en) | 2013-03-15 | 2017-08-22 | Medos International Sàrl | Surgical constructs with collapsing suture loop and methods for securing tissue |
US11672522B2 (en) | 2013-03-15 | 2023-06-13 | Medos International Sarl | Surgical constructs with collapsing suture loop and methods for securing tissue |
US9743947B2 (en) | 2013-03-15 | 2017-08-29 | Ethicon Endo-Surgery, Llc | End effector with a clamp arm assembly and blade |
US10842481B2 (en) | 2013-06-07 | 2020-11-24 | Biomet Sports Medicine, Llc | Method and apparatus for coupling soft tissue to bone |
US9936940B2 (en) | 2013-06-07 | 2018-04-10 | Biomet Sports Medicine, Llc | Method and apparatus for coupling soft tissue to bone |
US11166711B2 (en) | 2013-07-30 | 2021-11-09 | Arcuro Medical Ltd. | Joining devices, kits and methods |
US20160174963A1 (en) * | 2013-07-30 | 2016-06-23 | Arcuro Medical Ltd. | Joining devices, kits and methods |
US10058320B2 (en) * | 2013-07-30 | 2018-08-28 | Arcuro Medical Ltd. | Joining devices, kits and methods |
US10918373B2 (en) | 2013-08-31 | 2021-02-16 | Edwards Lifesciences Corporation | Devices and methods for locating and implanting tissue anchors at mitral valve commissure |
US10925659B2 (en) | 2013-09-13 | 2021-02-23 | Ethicon Llc | Electrosurgical (RF) medical instruments for cutting and coagulating tissue |
US10912603B2 (en) | 2013-11-08 | 2021-02-09 | Ethicon Llc | Electrosurgical devices |
US11033292B2 (en) | 2013-12-16 | 2021-06-15 | Cilag Gmbh International | Medical device |
US10912580B2 (en) | 2013-12-16 | 2021-02-09 | Ethicon Llc | Medical device |
US10136886B2 (en) | 2013-12-20 | 2018-11-27 | Biomet Sports Medicine, Llc | Knotless soft tissue devices and techniques |
US10806443B2 (en) | 2013-12-20 | 2020-10-20 | Biomet Sports Medicine, Llc | Knotless soft tissue devices and techniques |
US11648004B2 (en) | 2013-12-20 | 2023-05-16 | Biomet Sports Medicine, Llc | Knotless soft tissue devices and techniques |
US10856929B2 (en) | 2014-01-07 | 2020-12-08 | Ethicon Llc | Harvesting energy from a surgical generator |
US10779879B2 (en) | 2014-03-18 | 2020-09-22 | Ethicon Llc | Detecting short circuits in electrosurgical medical devices |
US10932847B2 (en) | 2014-03-18 | 2021-03-02 | Ethicon Llc | Detecting short circuits in electrosurgical medical devices |
US11399855B2 (en) | 2014-03-27 | 2022-08-02 | Cilag Gmbh International | Electrosurgical devices |
US10463421B2 (en) | 2014-03-27 | 2019-11-05 | Ethicon Llc | Two stage trigger, clamp and cut bipolar vessel sealer |
US11471209B2 (en) | 2014-03-31 | 2022-10-18 | Cilag Gmbh International | Controlling impedance rise in electrosurgical medical devices |
US10349999B2 (en) | 2014-03-31 | 2019-07-16 | Ethicon Llc | Controlling impedance rise in electrosurgical medical devices |
US11337747B2 (en) | 2014-04-15 | 2022-05-24 | Cilag Gmbh International | Software algorithms for electrosurgical instruments |
US9615822B2 (en) | 2014-05-30 | 2017-04-11 | Biomet Sports Medicine, Llc | Insertion tools and method for soft anchor |
US9700291B2 (en) | 2014-06-03 | 2017-07-11 | Biomet Sports Medicine, Llc | Capsule retractor |
US9795375B2 (en) * | 2014-06-15 | 2017-10-24 | Anchora Medical Ltd. | Apparatus and method for suturing a tissue |
US20160242761A1 (en) * | 2014-06-15 | 2016-08-25 | Anchora Medical Ltd. | Apparatus and method for suturing a tissue |
US10245169B2 (en) * | 2014-06-20 | 2019-04-02 | Endo Tools Therapeutics S.A. | Assembly for securing gastrointestinal tissue folds |
US9700333B2 (en) | 2014-06-30 | 2017-07-11 | Ethicon Llc | Surgical instrument with variable tissue compression |
US10285724B2 (en) | 2014-07-31 | 2019-05-14 | Ethicon Llc | Actuation mechanisms and load adjustment assemblies for surgical instruments |
US11413060B2 (en) | 2014-07-31 | 2022-08-16 | Cilag Gmbh International | Actuation mechanisms and load adjustment assemblies for surgical instruments |
WO2016028978A1 (en) * | 2014-08-20 | 2016-02-25 | Yale University | Assemblies and methodologies for the repair of hernias |
US20170273772A1 (en) * | 2014-08-20 | 2017-09-28 | Yale University | Assemblies And Methodologies For The Repair Of Hernias |
US10039543B2 (en) | 2014-08-22 | 2018-08-07 | Biomet Sports Medicine, Llc | Non-sliding soft anchor |
US11219443B2 (en) | 2014-08-22 | 2022-01-11 | Biomet Sports Medicine, Llc | Non-sliding soft anchor |
US10743856B2 (en) | 2014-08-22 | 2020-08-18 | Biomet Sports Medicine, Llc | Non-sliding soft anchor |
US10085735B2 (en) * | 2014-10-29 | 2018-10-02 | Smith & Nephew, Inc. | Modular tissue repair kit and devices and method related thereto |
US20160120535A1 (en) * | 2014-10-29 | 2016-05-05 | Smith & Nephew, Inc. | Modular tissue repair kit and devices and method related thereto |
US9687223B2 (en) | 2014-12-04 | 2017-06-27 | Coloplast A/S | Tissue anchor system |
US10136981B2 (en) | 2014-12-04 | 2018-11-27 | Coloplast A/S | Tissue anchor system including a suture securing an anchor to a support |
US9510822B2 (en) | 2014-12-04 | 2016-12-06 | Coloplast A/S | Tissue anchor |
US10022116B2 (en) | 2014-12-04 | 2018-07-17 | Coloplast A/S | Method of fixating an implantable material in a patient |
US10022117B2 (en) | 2014-12-04 | 2018-07-17 | Coloplast A/S | Method of treating urinary incontinence |
US10639092B2 (en) | 2014-12-08 | 2020-05-05 | Ethicon Llc | Electrode configurations for surgical instruments |
US10433826B2 (en) | 2014-12-15 | 2019-10-08 | Vivasure Medical Limited | Closure apparatus with flexible sealable member and flexible support member |
US11141142B2 (en) | 2014-12-15 | 2021-10-12 | Vivasure Medical Limited | Implantable sealable member with mesh layer |
US10206668B2 (en) | 2014-12-15 | 2019-02-19 | Vivasure Medical Limited | Implantable sealable member with mesh layer |
US11478235B2 (en) | 2014-12-15 | 2022-10-25 | Vivasure Medical Limited | Closure apparatus with flexible sealable member and flexible support member |
US10751109B2 (en) | 2014-12-22 | 2020-08-25 | Ethicon Llc | High power battery powered RF amplifier topology |
US10213303B2 (en) | 2015-02-02 | 2019-02-26 | On-X Life Technologies, Inc. | Rapid deployment artificial chordae Tendinae system |
US9480565B2 (en) * | 2015-02-02 | 2016-11-01 | On-X Life Technologies, Inc. | Rapid deployment artificial chordae tendinae system |
US11311326B2 (en) | 2015-02-06 | 2022-04-26 | Cilag Gmbh International | Electrosurgical instrument with rotation and articulation mechanisms |
CN107427297A (en) * | 2015-02-06 | 2017-12-01 | 医疗创新开发公司 | Skin expansion system |
CN107427297B (en) * | 2015-02-06 | 2020-10-20 | 医疗创新开发公司 | Skin dilation system |
US9955980B2 (en) | 2015-02-24 | 2018-05-01 | Biomet Sports Medicine, Llc | Anatomic soft tissue repair |
US10321950B2 (en) | 2015-03-17 | 2019-06-18 | Ethicon Llc | Managing tissue treatment |
US10342602B2 (en) | 2015-03-17 | 2019-07-09 | Ethicon Llc | Managing tissue treatment |
US10595929B2 (en) | 2015-03-24 | 2020-03-24 | Ethicon Llc | Surgical instruments with firing system overload protection mechanisms |
US10912551B2 (en) | 2015-03-31 | 2021-02-09 | Biomet Sports Medicine, Llc | Suture anchor with soft anchor of electrospun fibers |
US10314638B2 (en) | 2015-04-07 | 2019-06-11 | Ethicon Llc | Articulating radio frequency (RF) tissue seal with articulating state sensing |
US10034684B2 (en) | 2015-06-15 | 2018-07-31 | Ethicon Llc | Apparatus and method for dissecting and coagulating tissue |
US11020140B2 (en) | 2015-06-17 | 2021-06-01 | Cilag Gmbh International | Ultrasonic surgical blade for use with ultrasonic surgical instruments |
US10765470B2 (en) | 2015-06-30 | 2020-09-08 | Ethicon Llc | Surgical system with user adaptable techniques employing simultaneous energy modalities based on tissue parameters |
US10898256B2 (en) | 2015-06-30 | 2021-01-26 | Ethicon Llc | Surgical system with user adaptable techniques based on tissue impedance |
US11903634B2 (en) | 2015-06-30 | 2024-02-20 | Cilag Gmbh International | Surgical instrument with user adaptable techniques |
US11553954B2 (en) | 2015-06-30 | 2023-01-17 | Cilag Gmbh International | Translatable outer tube for sealing using shielded lap chole dissector |
US11129669B2 (en) | 2015-06-30 | 2021-09-28 | Cilag Gmbh International | Surgical system with user adaptable techniques based on tissue type |
US10034704B2 (en) | 2015-06-30 | 2018-07-31 | Ethicon Llc | Surgical instrument with user adaptable algorithms |
US10952788B2 (en) | 2015-06-30 | 2021-03-23 | Ethicon Llc | Surgical instrument with user adaptable algorithms |
US10357303B2 (en) | 2015-06-30 | 2019-07-23 | Ethicon Llc | Translatable outer tube for sealing using shielded lap chole dissector |
US11141213B2 (en) | 2015-06-30 | 2021-10-12 | Cilag Gmbh International | Surgical instrument with user adaptable techniques |
US11051873B2 (en) | 2015-06-30 | 2021-07-06 | Cilag Gmbh International | Surgical system with user adaptable techniques employing multiple energy modalities based on tissue parameters |
US10154852B2 (en) | 2015-07-01 | 2018-12-18 | Ethicon Llc | Ultrasonic surgical blade with improved cutting and coagulation features |
US10376367B2 (en) | 2015-07-02 | 2019-08-13 | First Ray, LLC | Orthopedic fasteners, instruments and methods |
US10130354B2 (en) | 2015-08-17 | 2018-11-20 | Arthrex, Inc. | Limited sliding suture in suture anchor |
US11058475B2 (en) | 2015-09-30 | 2021-07-13 | Cilag Gmbh International | Method and apparatus for selecting operations of a surgical instrument based on user intention |
US10624691B2 (en) | 2015-09-30 | 2020-04-21 | Ethicon Llc | Techniques for operating generator for digitally generating electrical signal waveforms and surgical instruments |
US10194973B2 (en) | 2015-09-30 | 2019-02-05 | Ethicon Llc | Generator for digitally generating electrical signal waveforms for electrosurgical and ultrasonic surgical instruments |
US10687884B2 (en) | 2015-09-30 | 2020-06-23 | Ethicon Llc | Circuits for supplying isolated direct current (DC) voltage to surgical instruments |
US11559347B2 (en) | 2015-09-30 | 2023-01-24 | Cilag Gmbh International | Techniques for circuit topologies for combined generator |
US10736685B2 (en) | 2015-09-30 | 2020-08-11 | Ethicon Llc | Generator for digitally generating combined electrical signal waveforms for ultrasonic surgical instruments |
US10610286B2 (en) | 2015-09-30 | 2020-04-07 | Ethicon Llc | Techniques for circuit topologies for combined generator |
US11766287B2 (en) | 2015-09-30 | 2023-09-26 | Cilag Gmbh International | Methods for operating generator for digitally generating electrical signal waveforms and surgical instruments |
US11033322B2 (en) | 2015-09-30 | 2021-06-15 | Ethicon Llc | Circuit topologies for combined generator |
US10751108B2 (en) | 2015-09-30 | 2020-08-25 | Ethicon Llc | Protection techniques for generator for digitally generating electrosurgical and ultrasonic electrical signal waveforms |
US10595930B2 (en) | 2015-10-16 | 2020-03-24 | Ethicon Llc | Electrode wiping surgical device |
US11666375B2 (en) | 2015-10-16 | 2023-06-06 | Cilag Gmbh International | Electrode wiping surgical device |
US10959771B2 (en) | 2015-10-16 | 2021-03-30 | Ethicon Llc | Suction and irrigation sealing grasper |
US11744651B2 (en) | 2015-10-21 | 2023-09-05 | P Tech, Llc | Systems and methods for navigation and visualization |
US10058393B2 (en) | 2015-10-21 | 2018-08-28 | P Tech, Llc | Systems and methods for navigation and visualization |
US10765484B2 (en) | 2015-10-21 | 2020-09-08 | P Tech, Llc | Systems and methods for navigation and visualization |
US11684430B2 (en) | 2015-10-21 | 2023-06-27 | P Tech, Llc | Systems and methods for navigation and visualization |
US11317974B2 (en) | 2015-10-21 | 2022-05-03 | P Tech, Llc | Systems and methods for navigation and visualization |
US10357260B2 (en) | 2015-11-02 | 2019-07-23 | First Ray, LLC | Orthopedic fastener, retainer, and guide methods |
US10702290B2 (en) | 2015-11-02 | 2020-07-07 | First Ray, LLC | Orthopedic fastener, retainer, and guide |
US11806005B2 (en) | 2015-12-04 | 2023-11-07 | Crossroads Extremity Systems, Llc | Devices and methods for anchoring tissue |
US10653409B2 (en) | 2015-12-04 | 2020-05-19 | Crossroads Extremity Systems, Llc | Devices and methods for anchoring tissue |
US11311280B2 (en) | 2015-12-15 | 2022-04-26 | Vivasure Medical Limited | Arteriotomy closure apparatus with slotted shoe for advantageous pressure distribution |
US10179022B2 (en) | 2015-12-30 | 2019-01-15 | Ethicon Llc | Jaw position impedance limiter for electrosurgical instrument |
US10959806B2 (en) | 2015-12-30 | 2021-03-30 | Ethicon Llc | Energized medical device with reusable handle |
US10575892B2 (en) | 2015-12-31 | 2020-03-03 | Ethicon Llc | Adapter for electrical surgical instruments |
US11751929B2 (en) | 2016-01-15 | 2023-09-12 | Cilag Gmbh International | Modular battery powered handheld surgical instrument with selective application of energy based on tissue characterization |
US10537351B2 (en) | 2016-01-15 | 2020-01-21 | Ethicon Llc | Modular battery powered handheld surgical instrument with variable motor control limits |
US11974772B2 (en) | 2016-01-15 | 2024-05-07 | Cilag GmbH Intemational | Modular battery powered handheld surgical instrument with variable motor control limits |
US11229471B2 (en) | 2016-01-15 | 2022-01-25 | Cilag Gmbh International | Modular battery powered handheld surgical instrument with selective application of energy based on tissue characterization |
US10709469B2 (en) | 2016-01-15 | 2020-07-14 | Ethicon Llc | Modular battery powered handheld surgical instrument with energy conservation techniques |
US11229450B2 (en) | 2016-01-15 | 2022-01-25 | Cilag Gmbh International | Modular battery powered handheld surgical instrument with motor drive |
US10779849B2 (en) | 2016-01-15 | 2020-09-22 | Ethicon Llc | Modular battery powered handheld surgical instrument with voltage sag resistant battery pack |
US11896280B2 (en) | 2016-01-15 | 2024-02-13 | Cilag Gmbh International | Clamp arm comprising a circuit |
US10299821B2 (en) | 2016-01-15 | 2019-05-28 | Ethicon Llc | Modular battery powered handheld surgical instrument with motor control limit profile |
US11129670B2 (en) | 2016-01-15 | 2021-09-28 | Cilag Gmbh International | Modular battery powered handheld surgical instrument with selective application of energy based on button displacement, intensity, or local tissue characterization |
US11058448B2 (en) | 2016-01-15 | 2021-07-13 | Cilag Gmbh International | Modular battery powered handheld surgical instrument with multistage generator circuits |
US10716615B2 (en) | 2016-01-15 | 2020-07-21 | Ethicon Llc | Modular battery powered handheld surgical instrument with curved end effectors having asymmetric engagement between jaw and blade |
US11684402B2 (en) | 2016-01-15 | 2023-06-27 | Cilag Gmbh International | Modular battery powered handheld surgical instrument with selective application of energy based on tissue characterization |
US10251664B2 (en) | 2016-01-15 | 2019-04-09 | Ethicon Llc | Modular battery powered handheld surgical instrument with multi-function motor via shifting gear assembly |
US11051840B2 (en) | 2016-01-15 | 2021-07-06 | Ethicon Llc | Modular battery powered handheld surgical instrument with reusable asymmetric handle housing |
US11134978B2 (en) | 2016-01-15 | 2021-10-05 | Cilag Gmbh International | Modular battery powered handheld surgical instrument with self-diagnosing control switches for reusable handle assembly |
US10828058B2 (en) | 2016-01-15 | 2020-11-10 | Ethicon Llc | Modular battery powered handheld surgical instrument with motor control limits based on tissue characterization |
US10842523B2 (en) | 2016-01-15 | 2020-11-24 | Ethicon Llc | Modular battery powered handheld surgical instrument and methods therefor |
US20170215864A1 (en) * | 2016-02-01 | 2017-08-03 | DePuy Synthes Products, Inc. | Tissue augmentation constructs for use with soft tissue fixation repair systems and methods |
US11937803B2 (en) | 2016-02-01 | 2024-03-26 | Medos International Sarl | Soft tissue fixation repair methods using tissue augmentation constructs |
US11523812B2 (en) * | 2016-02-01 | 2022-12-13 | Medos International Sarl | Soft tissue fixation repair methods using tissue augmentation constructs |
CN108738302A (en) * | 2016-02-01 | 2018-11-02 | 美多斯国际有限公司 | The tissue enhancing holder that repair system is used together with method is fixed with soft tissue |
US20170215865A1 (en) * | 2016-02-01 | 2017-08-03 | DePuy Synthes Products, Inc. | Soft tissue fixation repair methods using tissue augmentation constructs |
US20170273680A1 (en) * | 2016-02-01 | 2017-09-28 | DePuy Synthes Products, Inc. | Tissue augmentation tacks for use with soft tissue fixation repair systems and methods |
US11484401B2 (en) | 2016-02-01 | 2022-11-01 | Medos International Sarl | Tissue augmentation scaffolds for use in soft tissue fixation repair |
US10702260B2 (en) | 2016-02-01 | 2020-07-07 | Medos International Sàrl | Soft tissue fixation repair methods using tissue augmentation scaffolds |
US11357495B2 (en) | 2016-02-01 | 2022-06-14 | Medos International Sarl | Tissue augmentation scaffolds for use with soft tissue fixation repair systems and methods |
US11938017B2 (en) | 2016-02-01 | 2024-03-26 | Medos International Srl | Tissue augmentation scaffolds for use in soft tissue fixation repair |
US10555769B2 (en) | 2016-02-22 | 2020-02-11 | Ethicon Llc | Flexible circuits for electrosurgical instrument |
US11202670B2 (en) | 2016-02-22 | 2021-12-21 | Cilag Gmbh International | Method of manufacturing a flexible circuit electrode for electrosurgical instrument |
US10568617B2 (en) * | 2016-04-20 | 2020-02-25 | Medos International Sarl | Meniscal repair devices, systems, and methods |
US20170303908A1 (en) * | 2016-04-20 | 2017-10-26 | DePuy Synthes Products, Inc. | Meniscal repair devices, systems, and methods |
US20170303907A1 (en) * | 2016-04-20 | 2017-10-26 | DePuy Synthes Products, Inc. | Meniscal repair devices, systems, and methods |
US11826037B2 (en) | 2016-04-20 | 2023-11-28 | Medos International Sarl | Meniscal repair devices, systems, and methods |
US10390814B2 (en) | 2016-04-20 | 2019-08-27 | Medos International Sarl | Meniscal repair devices, systems, and methods |
CN107440774A (en) * | 2016-04-20 | 2017-12-08 | 美多斯国际有限公司 | Meniscal repair device, system and method |
US11419599B2 (en) * | 2016-04-20 | 2022-08-23 | Medos International Sarl | Meniscal repair devices, systems, and methods |
US11672521B2 (en) | 2016-04-20 | 2023-06-13 | Medos International Sarl | Meniscal repair devices, systems, and methods |
US10709435B2 (en) | 2016-04-20 | 2020-07-14 | Medos International Sarl | Meniscal repair devices, systems, and methods |
US10299782B2 (en) * | 2016-04-20 | 2019-05-28 | Medos International Sarl | Meniscal repair devices, systems, and methods |
US10485607B2 (en) | 2016-04-29 | 2019-11-26 | Ethicon Llc | Jaw structure with distal closure for electrosurgical instruments |
US10646269B2 (en) | 2016-04-29 | 2020-05-12 | Ethicon Llc | Non-linear jaw gap for electrosurgical instruments |
US10987156B2 (en) | 2016-04-29 | 2021-04-27 | Ethicon Llc | Electrosurgical instrument with electrically conductive gap setting member and electrically insulative tissue engaging members |
US10856934B2 (en) | 2016-04-29 | 2020-12-08 | Ethicon Llc | Electrosurgical instrument with electrically conductive gap setting and tissue engaging members |
US10702329B2 (en) | 2016-04-29 | 2020-07-07 | Ethicon Llc | Jaw structure with distal post for electrosurgical instruments |
US10456193B2 (en) | 2016-05-03 | 2019-10-29 | Ethicon Llc | Medical device with a bilateral jaw configuration for nerve stimulation |
US11864820B2 (en) | 2016-05-03 | 2024-01-09 | Cilag Gmbh International | Medical device with a bilateral jaw configuration for nerve stimulation |
US10932769B2 (en) | 2016-05-26 | 2021-03-02 | Ivy Sports Medicine, Llc | System and method for all-inside suture fixation for implant attachment and soft tissue repair |
US11696752B2 (en) | 2016-05-26 | 2023-07-11 | Stryker Corporation | Systems and methods for all-inside suture fixation for implant attachment and soft tissue repair |
US11103350B2 (en) | 2016-06-01 | 2021-08-31 | On-X Life Technologies, Inc. | Pull-through chordae tendineae system |
US10245064B2 (en) | 2016-07-12 | 2019-04-02 | Ethicon Llc | Ultrasonic surgical instrument with piezoelectric central lumen transducer |
US10966744B2 (en) | 2016-07-12 | 2021-04-06 | Ethicon Llc | Ultrasonic surgical instrument with piezoelectric central lumen transducer |
US11883055B2 (en) | 2016-07-12 | 2024-01-30 | Cilag Gmbh International | Ultrasonic surgical instrument with piezoelectric central lumen transducer |
US10893883B2 (en) | 2016-07-13 | 2021-01-19 | Ethicon Llc | Ultrasonic assembly for use with ultrasonic surgical instruments |
US10842522B2 (en) | 2016-07-15 | 2020-11-24 | Ethicon Llc | Ultrasonic surgical instruments having offset blades |
US11344362B2 (en) | 2016-08-05 | 2022-05-31 | Cilag Gmbh International | Methods and systems for advanced harmonic energy |
US10376305B2 (en) | 2016-08-05 | 2019-08-13 | Ethicon Llc | Methods and systems for advanced harmonic energy |
US10285723B2 (en) | 2016-08-09 | 2019-05-14 | Ethicon Llc | Ultrasonic surgical blade with improved heel portion |
USD847990S1 (en) | 2016-08-16 | 2019-05-07 | Ethicon Llc | Surgical instrument |
USD924400S1 (en) | 2016-08-16 | 2021-07-06 | Cilag Gmbh International | Surgical instrument |
US10420580B2 (en) | 2016-08-25 | 2019-09-24 | Ethicon Llc | Ultrasonic transducer for surgical instrument |
US10952759B2 (en) | 2016-08-25 | 2021-03-23 | Ethicon Llc | Tissue loading of a surgical instrument |
US11350959B2 (en) | 2016-08-25 | 2022-06-07 | Cilag Gmbh International | Ultrasonic transducer techniques for ultrasonic surgical instrument |
US11925378B2 (en) | 2016-08-25 | 2024-03-12 | Cilag Gmbh International | Ultrasonic transducer for surgical instrument |
US10779847B2 (en) | 2016-08-25 | 2020-09-22 | Ethicon Llc | Ultrasonic transducer to waveguide joining |
US11839422B2 (en) | 2016-09-23 | 2023-12-12 | Cilag Gmbh International | Electrosurgical instrument with fluid diverter |
US10751117B2 (en) | 2016-09-23 | 2020-08-25 | Ethicon Llc | Electrosurgical instrument with fluid diverter |
US10772622B2 (en) | 2016-10-27 | 2020-09-15 | Smith & Nephew, Inc. | Tissue repair device |
US10299829B2 (en) | 2016-11-07 | 2019-05-28 | Ronald Yamada | Tissue repair system |
US11304691B2 (en) | 2016-11-13 | 2022-04-19 | Anchora Medical Ltd. | Minimally-invasive tissue suturing device |
US10603064B2 (en) | 2016-11-28 | 2020-03-31 | Ethicon Llc | Ultrasonic transducer |
US11266430B2 (en) | 2016-11-29 | 2022-03-08 | Cilag Gmbh International | End effector control and calibration |
US11033325B2 (en) | 2017-02-16 | 2021-06-15 | Cilag Gmbh International | Electrosurgical instrument with telescoping suction port and debris cleaner |
US10799284B2 (en) | 2017-03-15 | 2020-10-13 | Ethicon Llc | Electrosurgical instrument with textured jaws |
US11497546B2 (en) | 2017-03-31 | 2022-11-15 | Cilag Gmbh International | Area ratios of patterned coatings on RF electrodes to reduce sticking |
US10603117B2 (en) | 2017-06-28 | 2020-03-31 | Ethicon Llc | Articulation state detection mechanisms |
US10820920B2 (en) | 2017-07-05 | 2020-11-03 | Ethicon Llc | Reusable ultrasonic medical devices and methods of their use |
US11033323B2 (en) | 2017-09-29 | 2021-06-15 | Cilag Gmbh International | Systems and methods for managing fluid and suction in electrosurgical systems |
US11490951B2 (en) | 2017-09-29 | 2022-11-08 | Cilag Gmbh International | Saline contact with electrodes |
US11484358B2 (en) | 2017-09-29 | 2022-11-01 | Cilag Gmbh International | Flexible electrosurgical instrument |
KR102594821B1 (en) | 2018-09-28 | 2023-10-27 | 콘메드 코포레이션 | Systems and methods for repairing soft tissue tears |
AU2019346660B2 (en) * | 2018-09-28 | 2022-07-28 | Conmed Corporation | System for repairing soft tissue tears |
JP2022501134A (en) * | 2018-09-28 | 2022-01-06 | コンメッド コーポレーション | A system for repairing soft tissue ruptures |
JP7403539B2 (en) | 2018-09-28 | 2023-12-22 | コンメッド コーポレーション | System for repairing soft tissue tears |
WO2020069486A1 (en) * | 2018-09-28 | 2020-04-02 | Conmed Corporation | System for repairing soft tissue tears |
KR20210065132A (en) * | 2018-09-28 | 2021-06-03 | 콘메드 코포레이션 | Systems and methods for repairing soft tissue tears |
US11375994B2 (en) * | 2019-07-12 | 2022-07-05 | Abbot Cardiovascular Systems, Inc. | Methods, systems, and devices for positioning sutures for closing an opening in tissue |
US11452525B2 (en) | 2019-12-30 | 2022-09-27 | Cilag Gmbh International | Surgical instrument comprising an adjustment system |
US11759251B2 (en) | 2019-12-30 | 2023-09-19 | Cilag Gmbh International | Control program adaptation based on device status and user input |
US11696776B2 (en) | 2019-12-30 | 2023-07-11 | Cilag Gmbh International | Articulatable surgical instrument |
US11974801B2 (en) | 2019-12-30 | 2024-05-07 | Cilag Gmbh International | Electrosurgical instrument with flexible wiring assemblies |
US11812957B2 (en) | 2019-12-30 | 2023-11-14 | Cilag Gmbh International | Surgical instrument comprising a signal interference resolution system |
US11786291B2 (en) | 2019-12-30 | 2023-10-17 | Cilag Gmbh International | Deflectable support of RF energy electrode with respect to opposing ultrasonic blade |
US11589916B2 (en) | 2019-12-30 | 2023-02-28 | Cilag Gmbh International | Electrosurgical instruments with electrodes having variable energy densities |
US11723716B2 (en) | 2019-12-30 | 2023-08-15 | Cilag Gmbh International | Electrosurgical instrument with variable control mechanisms |
US11779387B2 (en) | 2019-12-30 | 2023-10-10 | Cilag Gmbh International | Clamp arm jaw to minimize tissue sticking and improve tissue control |
US11684412B2 (en) | 2019-12-30 | 2023-06-27 | Cilag Gmbh International | Surgical instrument with rotatable and articulatable surgical end effector |
US11779329B2 (en) | 2019-12-30 | 2023-10-10 | Cilag Gmbh International | Surgical instrument comprising a flex circuit including a sensor system |
US11950797B2 (en) | 2019-12-30 | 2024-04-09 | Cilag Gmbh International | Deflectable electrode with higher distal bias relative to proximal bias |
US11944366B2 (en) | 2019-12-30 | 2024-04-02 | Cilag Gmbh International | Asymmetric segmented ultrasonic support pad for cooperative engagement with a movable RF electrode |
US11707318B2 (en) | 2019-12-30 | 2023-07-25 | Cilag Gmbh International | Surgical instrument with jaw alignment features |
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US20220031300A1 (en) * | 2020-07-28 | 2022-02-03 | Mentor Worldwide Llc | Quick, one-handed interrupted suture fixation for approximating tissue without the need to tie knots |
US11723649B2 (en) * | 2020-07-28 | 2023-08-15 | Mentor Worldwide Llc | Quick, one-handed interrupted suture fixation for approximating tissue without the need to tie knots |
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US20220061832A1 (en) * | 2020-08-31 | 2022-03-03 | Healthium Medtech Limited | Tissue Repair Device and Method to Repair Tissue by Deploying Implants |
US20220079576A1 (en) * | 2020-09-15 | 2022-03-17 | Smith & Nephew, Inc. | Joint repair augmentation |
WO2022188376A1 (en) * | 2021-03-12 | 2022-09-15 | 杭州锐健马斯汀医疗器材有限公司 | Implant, implant forming method, and suture instrument |
US11389154B1 (en) * | 2021-04-08 | 2022-07-19 | Integrity Orthopaedics, Inc. | Knotless micro suture anchor array for high density anatomical attachment of soft tissue to bone |
US11382612B1 (en) * | 2021-04-08 | 2022-07-12 | Integrity Orthopaedics, Inc. | Method for creating a tensionable and lockable suture anchor array for anatomical attachment of tissue to bone |
US11957342B2 (en) | 2021-11-01 | 2024-04-16 | Cilag Gmbh International | Devices, systems, and methods for detecting tissue and foreign objects during a surgical operation |
Also Published As
Publication number | Publication date |
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US7153312B1 (en) | 2006-12-26 |
US20140350599A1 (en) | 2014-11-27 |
US8834524B2 (en) | 2014-09-16 |
US20050283192A1 (en) | 2005-12-22 |
US8512375B2 (en) | 2013-08-20 |
US9492160B2 (en) | 2016-11-15 |
US20130310874A1 (en) | 2013-11-21 |
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