UA99604C2 - Соль нападисилата как антагонист мускаринового рецептора м3 - Google Patents
Соль нападисилата как антагонист мускаринового рецептора м3Info
- Publication number
- UA99604C2 UA99604C2 UAA200907421A UAA200907421A UA99604C2 UA 99604 C2 UA99604 C2 UA 99604C2 UA A200907421 A UAA200907421 A UA A200907421A UA A200907421 A UAA200907421 A UA A200907421A UA 99604 C2 UA99604 C2 UA 99604C2
- Authority
- UA
- Ukraine
- Prior art keywords
- muscarinic
- antagonist
- napadisylate salt
- napadisylate
- methyl
- Prior art date
Links
- 239000003681 muscarinic M3 receptor antagonist Substances 0.000 title 1
- 150000003839 salts Chemical class 0.000 title 1
- STTGOFBGRUQUOE-NDEPHWFRSA-N 2-[(4-chlorophenyl)methoxy]ethyl-[[2-[(r)-cyclohexyl-hydroxy-phenylmethyl]-1,3-oxazol-5-yl]methyl]-dimethylazanium Chemical compound C=1N=C([C@@](O)(C2CCCCC2)C=2C=CC=CC=2)OC=1C[N+](C)(C)CCOCC1=CC=C(Cl)C=C1 STTGOFBGRUQUOE-NDEPHWFRSA-N 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 238000002560 therapeutic procedure Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
- A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/42—Oxazoles
- A61K31/421—1,3-Oxazoles, e.g. pemoline, trimethadione
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/428—Thiazoles condensed with carbocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB0702385.6A GB0702385D0 (en) | 2007-02-07 | 2007-02-07 | New combination |
Publications (1)
Publication Number | Publication Date |
---|---|
UA99604C2 true UA99604C2 (ru) | 2012-09-10 |
Family
ID=37898913
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
UAA200907421A UA99604C2 (ru) | 2007-02-07 | 2008-02-06 | Соль нападисилата как антагонист мускаринового рецептора м3 |
Country Status (18)
Country | Link |
---|---|
US (1) | US20110046191A1 (ru) |
EP (1) | EP2124941A1 (ru) |
JP (1) | JP5337054B2 (ru) |
KR (1) | KR20090114389A (ru) |
CN (2) | CN101636390B (ru) |
AR (1) | AR065202A1 (ru) |
AU (1) | AU2008212649B2 (ru) |
BR (1) | BRPI0806966A2 (ru) |
CA (1) | CA2675718A1 (ru) |
CL (1) | CL2008000380A1 (ru) |
GB (1) | GB0702385D0 (ru) |
MX (1) | MX2009008363A (ru) |
PE (1) | PE20081751A1 (ru) |
RU (1) | RU2460527C2 (ru) |
TW (1) | TW200901986A (ru) |
UA (1) | UA99604C2 (ru) |
WO (1) | WO2008096126A1 (ru) |
ZA (1) | ZA200905106B (ru) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB0516313D0 (en) * | 2005-08-08 | 2005-09-14 | Argenta Discovery Ltd | Azole derivatives and their uses |
TW200825084A (en) | 2006-11-14 | 2008-06-16 | Astrazeneca Ab | New compounds 521 |
GB0704000D0 (en) * | 2007-03-01 | 2007-04-11 | Astrazeneca Ab | Salts 670 |
EP2300464A1 (en) | 2008-05-13 | 2011-03-30 | AstraZeneca AB | Quinuclidine derivatives as muscarinic m3 receptor antagonists |
WO2009154562A1 (en) * | 2008-06-20 | 2009-12-23 | Astrazeneca Ab | Pharmaceutical composition comprising a 4-hydroxy-2-oxo-2, 3- dihydro-1, 3-benzothiazol-7-yl compound for modulation of beta2-adrenoreceptor activity |
GB0814728D0 (en) * | 2008-08-12 | 2008-09-17 | Argenta Discovery Ltd | New combination |
GB0823140D0 (en) * | 2008-12-18 | 2009-01-28 | Astrazeneca Ab | New combination |
PL3061821T3 (pl) | 2009-07-22 | 2020-01-31 | PureTech Health LLC | Kompozycje do leczenia zaburzeń łagodzonych przez aktywację receptora muskarynowego |
US10265311B2 (en) | 2009-07-22 | 2019-04-23 | PureTech Health LLC | Methods and compositions for treatment of disorders ameliorated by muscarinic receptor activation |
BR112021005802B1 (pt) | 2018-09-28 | 2022-02-15 | Karuna Therapeutics, Inc | Composição farmacêutica oral |
CN109896934A (zh) * | 2019-03-08 | 2019-06-18 | 山东省药学科学院 | 一种高纯度2-苄氧基溴乙烷的制备方法 |
Family Cites Families (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3877470T2 (de) * | 1987-09-10 | 1993-06-24 | Merck Sharp & Dohme | Oxazole und thiazole zur behandlung seniler demenz. |
FR2675142B1 (fr) * | 1991-04-10 | 1993-06-25 | Roussel Uclaf | Nouveaux derives de l'acide alpha-methylene 4-[(phenoxy) methyl] 5-thiazolacetique, leur procede de preparation et les intermediaires de ce procede et leur application a titre de fongicides. |
GB9603755D0 (en) * | 1996-02-22 | 1996-04-24 | Pfizer Ltd | Therapeutic agents |
US6057340A (en) * | 1998-02-03 | 2000-05-02 | American Home Products Corporation | Oxazole derivatives as serotonin-1A receptor agonists |
US6242448B1 (en) * | 1998-12-17 | 2001-06-05 | American Home Products Corporation | Trisubstituted-oxazole derivatives as serotonin ligands |
SE9902935D0 (sv) * | 1999-08-18 | 1999-08-18 | Astra Pharma Prod | Pharmaceutical compositions |
US20020052312A1 (en) * | 2000-05-30 | 2002-05-02 | Reiss Theodore F. | Combination therapy of chronic obstructive pulmonary disease using muscarinic receptor antagonists |
US20020179087A1 (en) * | 2001-02-01 | 2002-12-05 | Karl-Heinz Bozung | Pharmaceutical compositions containing an oxitropium salt and a betamimetic |
US20020189610A1 (en) * | 2001-02-01 | 2002-12-19 | Karl-Heinz Bozung | Pharmaceutical compositions containing an ipratropium salt and a betamimetic |
US7417051B2 (en) * | 2002-04-12 | 2008-08-26 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Medicaments comprising betamimetics and a novel anticholinergic |
NZ538493A (en) * | 2002-08-29 | 2007-10-26 | Cipla Ltd | Pharmaceutical products and compositions comprising specific anticholinergic agents, beta-2 agonists and corticosteroids |
US7332175B2 (en) * | 2003-05-27 | 2008-02-19 | Boehringer Ingelheim International Gmbh | Long-acting drug combinations for the treatment of respiratory complaints |
US20050025718A1 (en) * | 2003-07-31 | 2005-02-03 | Boehringer Ingelheim International Gmbh | Medicaments for inhalation comprising an anticholinergic and a betamimetic |
US7745621B2 (en) * | 2004-05-14 | 2010-06-29 | Boehringer Ingelheim International Gmbh | Long acting bronchodilators for the treatment of respiratory diseases |
GB0516313D0 (en) * | 2005-08-08 | 2005-09-14 | Argenta Discovery Ltd | Azole derivatives and their uses |
TW200738658A (en) * | 2005-08-09 | 2007-10-16 | Astrazeneca Ab | Novel compounds |
WO2008017827A2 (en) * | 2006-08-08 | 2008-02-14 | Argenta Discovery Limited | Azole and thiazole derivatives and their uses |
WO2008096093A1 (en) * | 2007-02-06 | 2008-08-14 | Argenta Discovery Ltd. | Oxazole and thiazole derivatives and their uses |
-
2007
- 2007-02-07 GB GBGB0702385.6A patent/GB0702385D0/en not_active Ceased
-
2008
- 2008-02-05 TW TW097104738A patent/TW200901986A/zh unknown
- 2008-02-06 AU AU2008212649A patent/AU2008212649B2/en not_active Ceased
- 2008-02-06 MX MX2009008363A patent/MX2009008363A/es active IP Right Grant
- 2008-02-06 CL CL200800380A patent/CL2008000380A1/es unknown
- 2008-02-06 CN CN2008800045221A patent/CN101636390B/zh not_active Expired - Fee Related
- 2008-02-06 BR BRPI0806966-2A2A patent/BRPI0806966A2/pt not_active IP Right Cessation
- 2008-02-06 UA UAA200907421A patent/UA99604C2/ru unknown
- 2008-02-06 AR ARP080100504A patent/AR065202A1/es unknown
- 2008-02-06 RU RU2009133261/15A patent/RU2460527C2/ru not_active IP Right Cessation
- 2008-02-06 CN CN2008800106615A patent/CN101678005B/zh not_active Expired - Fee Related
- 2008-02-06 US US12/523,171 patent/US20110046191A1/en not_active Abandoned
- 2008-02-06 EP EP08702062A patent/EP2124941A1/en not_active Withdrawn
- 2008-02-06 KR KR1020097016484A patent/KR20090114389A/ko not_active Application Discontinuation
- 2008-02-06 JP JP2009548735A patent/JP5337054B2/ja not_active Expired - Fee Related
- 2008-02-06 PE PE2008000265A patent/PE20081751A1/es not_active Application Discontinuation
- 2008-02-06 CA CA002675718A patent/CA2675718A1/en not_active Abandoned
- 2008-02-06 WO PCT/GB2008/000404 patent/WO2008096126A1/en active Application Filing
-
2009
- 2009-07-21 ZA ZA200905106A patent/ZA200905106B/xx unknown
Also Published As
Publication number | Publication date |
---|---|
CN101636390A (zh) | 2010-01-27 |
MX2009008363A (es) | 2009-08-20 |
WO2008096126A1 (en) | 2008-08-14 |
CN101678005B (zh) | 2012-10-31 |
CL2008000380A1 (es) | 2008-08-18 |
JP2010518059A (ja) | 2010-05-27 |
CA2675718A1 (en) | 2008-07-14 |
EP2124941A1 (en) | 2009-12-02 |
AU2008212649B2 (en) | 2011-05-19 |
TW200901986A (en) | 2009-01-16 |
RU2009133261A (ru) | 2011-03-20 |
GB0702385D0 (en) | 2007-03-21 |
KR20090114389A (ko) | 2009-11-03 |
JP5337054B2 (ja) | 2013-11-06 |
CN101636390B (zh) | 2013-06-12 |
AU2008212649A1 (en) | 2008-08-14 |
BRPI0806966A2 (pt) | 2014-04-08 |
PE20081751A1 (es) | 2008-12-27 |
CN101678005A (zh) | 2010-03-24 |
AR065202A1 (es) | 2009-05-20 |
RU2460527C2 (ru) | 2012-09-10 |
US20110046191A1 (en) | 2011-02-24 |
ZA200905106B (en) | 2010-05-26 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
UA99604C2 (ru) | Соль нападисилата как антагонист мускаринового рецептора м3 | |
WO2008096149A3 (en) | Napadisylate salt of a muscarinic m3 antagonist | |
EP1909772A4 (en) | TRANSDERMAL DRUG FORMULATION | |
EP2010125A4 (en) | DOS COUNTER | |
IL193894A (en) | Pharmaceuticals containing loliconazole for external use | |
IL174352A0 (en) | Medical devices for use with carpules | |
SI2063868T1 (sl) | Farmacevtski sestavki, ki vsebujejo kalcijev rosuvastatin | |
PL2058020T3 (pl) | Urządzenie do podawania leków | |
IL197316A0 (en) | Buprenophine-wafer for drug substitution therapy | |
ZA200801275B (en) | Pharmaceutical preparation containing meloxicam | |
GB0515584D0 (en) | Medicament dispenser | |
IL191940A0 (en) | Medicament dispenser | |
ZA200807484B (en) | Medicament containing fluoroquinolones | |
IL185889A0 (en) | Dispenser for delivering medicament | |
EP2010162A4 (en) | COMPOSITION FOR DISPOSING A MEDICINAL PRODUCT | |
GB0600070D0 (en) | Dose counter | |
EP1862183A4 (en) | PHARMACEUTICAL COMPOSITION WITH HEAVY WATER-SOLUBLE MEDICAMENT | |
EP1819323A4 (en) | PHARMACEUTICAL COMPOSITION WITH ANTI-SKIN COMPOSER | |
MX2012011382A (es) | Nuevo polimero. | |
JO2730B1 (en) | Medications for the treatment of endometriosis | |
IL195034A0 (en) | Liquid pharmaceutical formulation | |
IL199865A0 (en) | Methods of determining drug dose delivery | |
PL1996157T3 (pl) | Oftalmiczna kompozycja farmaceutyczna zawierająca amfifilowe kopolimery poliaspartamidu | |
WO2008146104A3 (en) | Stable liquid composition of chondroitinsulfate and glucosamine | |
EP2309856A4 (en) | PHARMACEUTICAL COMPOUNDS AS CYTOTOXICA AND ITS APPLICATION |