UA93814U - A method for diagnosing syndrome of retardation of fetus development and the degree of its severity - Google Patents

Abstract

The method for diagnosing fetal growth retardation and determination of the degree of its severity includes determination in woman's blood of placental dysfunction markers. Determined is the dynamics of changes in concentration of receptor of vascular endothelial growth factor (VEGF-R1) at different stages of pregnancy. At concentration of VEGF-R1 (2,32 ± 0,10) ng / ml at 16-19 weeks, at concentration (2,45 ± 0,18) ng / ml at 20-27 weeks, at concentration of (2,8 ± 0.21) ng / ml at 28-32 weeks, at concentration (4,25 ± 0,16) ng / ml at 33-37 weeks and at concentration (3,92 ± 0,12) ng / ml at 38- 40 weeks with the syndrome of fetal growth retardation (SFGR) of I degree is diagnosed. At concentration of VEGF-R1 (2,88 ± 0,77) ng / ml at 16-19 weeks, at concentration (3,84 ± 0,54) ng / ml at 20-27 weeks, at concentration (8,22 ± 0.66) ng / ml at 28-32 weeks, at concentration (9,86 ± 0,72) ng / ml at 33-37 weeks and at concentration (9,16 ± 0,54) ng / ml at 38- 40 weeks SFGR of II degree is diagnosed. At concentration of VEGF-R1 (4,24 ± 0,62) ng / ml at 16-19 weeks, at concentration (9,92 ± 0,88) ng / mlat 20-27 weeks with concentration of (11,4 ± 0.79) ng / ml at 28-32 weeks and at concentration (10,2 ± 0,76) ng / ml at 33-37 weeks SFGR of III degree is diagnosed.