UA93352C2 - Substituted indolyl alkyl amino derivatives as novel inhibitors of histone deacetylase - Google Patents

Substituted indolyl alkyl amino derivatives as novel inhibitors of histone deacetylase

Info

Publication number
UA93352C2
UA93352C2 UAA200614022A UAA200614022A UA93352C2 UA 93352 C2 UA93352 C2 UA 93352C2 UA A200614022 A UAA200614022 A UA A200614022A UA A200614022 A UAA200614022 A UA A200614022A UA 93352 C2 UA93352 C2 UA 93352C2
Authority
UA
Ukraine
Prior art keywords
alkyl amino
histone deacetylase
amino derivatives
substituted indolyl
novel inhibitors
Prior art date
Application number
UAA200614022A
Other languages
Russian (ru)
Ukrainian (uk)
Inventor
Марк Густааф Селин Вердонк
Патрик Рене Анжибо
Бруно Рю
Изабель Ноэль Констанс Пилатт
Хольте Петер Тен
Жанин Артс
Эмелен Кристоф Ван
Original Assignee
Янссен Фармацевтика H.B.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Янссен Фармацевтика H.B. filed Critical Янссен Фармацевтика H.B.
Publication of UA93352C2 publication Critical patent/UA93352C2/en

Links

Landscapes

  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

This invention comprises the novel compounds of formula (I) wherein R, R, R, X and Y have defined meanings, having histone deacelylase inhibiting enzymatic activity; their preparation, compositions containing them and their, use as drugs.(I)
UAA200614022A 2004-07-28 2005-07-25 Substituted indolyl alkyl amino derivatives as novel inhibitors of histone deacetylase UA93352C2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP04077172 2004-07-28

Publications (1)

Publication Number Publication Date
UA93352C2 true UA93352C2 (en) 2011-02-10

Family

ID=34928411

Family Applications (1)

Application Number Title Priority Date Filing Date
UAA200614022A UA93352C2 (en) 2004-07-28 2005-07-25 Substituted indolyl alkyl amino derivatives as novel inhibitors of histone deacetylase

Country Status (10)

Country Link
CN (1) CN1993353B (en)
AT (1) ATE542812T1 (en)
DK (1) DK1781639T3 (en)
ES (1) ES2381117T3 (en)
ME (1) ME01444B (en)
PT (1) PT1781639E (en)
RS (1) RS52304B (en)
SI (1) SI1781639T1 (en)
UA (1) UA93352C2 (en)
ZA (1) ZA200700764B (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107095871A (en) * 2016-02-22 2017-08-29 中国科学院上海巴斯德研究所 Quisinostat, a kind of new efficient antimalarial agent
CN107721980B (en) * 2017-08-25 2019-07-12 南京医科大学 The weary oxygen targeted prodrug and its application of a kind of fluorouracil and Quisinosta
CN112485233B (en) * 2020-11-03 2022-08-26 山东师范大学 Nano sensor for detecting deacetylase and detection method and application thereof

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR0307607A (en) * 2002-03-13 2004-12-21 Janssen Pharmaceutica Nv Carbonylamino derivatives as histone deacetylase inhibitors

Also Published As

Publication number Publication date
ZA200700764B (en) 2008-09-25
PT1781639E (en) 2012-05-02
ES2381117T3 (en) 2012-05-23
CN1993353A (en) 2007-07-04
SI1781639T1 (en) 2012-06-29
CN1993353B (en) 2010-12-01
DK1781639T3 (en) 2012-05-14
ATE542812T1 (en) 2012-02-15
RS52304B (en) 2012-12-31
ME01444B (en) 2013-12-20

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