UA88604C2 - Use of antibody binding to alfa-4-integrin for treatment of demyelinating diseases - Google Patents

Use of antibody binding to alfa-4-integrin for treatment of demyelinating diseases

Info

Publication number
UA88604C2
UA88604C2 UAA200508278A UA2005008278A UA88604C2 UA 88604 C2 UA88604 C2 UA 88604C2 UA A200508278 A UAA200508278 A UA A200508278A UA 2005008278 A UA2005008278 A UA 2005008278A UA 88604 C2 UA88604 C2 UA 88604C2
Authority
UA
Ukraine
Prior art keywords
demyelination
compositions
alfa
integrin
treatment
Prior art date
Application number
UAA200508278A
Other languages
Russian (ru)
Ukrainian (uk)
Inventor
Стив Дж. Карлик
Майкл А. Плисс
Андрей В. Конради
Франсин С. Грант
Кристофер М. Семко
Дарен Дрессен
Элизабет Мессерсмит
Стефен Фридман
Тед Йеднок
Original Assignee
Элан Фармасьютикалз, Инк.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Элан Фармасьютикалз, Инк. filed Critical Элан Фармасьютикалз, Инк.
Publication of UA88604C2 publication Critical patent/UA88604C2/en

Links

Abstract

The application provides for methods and compositions for inhibiting demyelination, promoting remyelination and/or treating paralysis in a subject in need thereof. Preferably, such compositions include immunoglobulins (e.g., antibodies, antibody fragments, and recombinantly produced antibodies or fragments), polypeptides (e.g., soluble forms of the ligand proteins for integrins) and small molecules, which when administered in an effective amount inhibits demyelination and/or promotes remyelination in a patient. The compositions and methods described herein can also utilize other anti-inflammatory agents used to palliate conditions and diseases associated with demyelination.
UAA200508278A 2003-01-24 2004-01-26 Use of antibody binding to alfa-4-integrin for treatment of demyelinating diseases UA88604C2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US44217103P 2003-01-24 2003-01-24

Publications (1)

Publication Number Publication Date
UA88604C2 true UA88604C2 (en) 2009-11-10

Family

ID=37959752

Family Applications (1)

Application Number Title Priority Date Filing Date
UAA200508278A UA88604C2 (en) 2003-01-24 2004-01-26 Use of antibody binding to alfa-4-integrin for treatment of demyelinating diseases

Country Status (3)

Country Link
CN (1) CN1942161B (en)
UA (1) UA88604C2 (en)
ZA (1) ZA200505869B (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2509573C2 (en) * 2010-07-27 2014-03-20 Олег Ильич Эпштейн Drug for treating multiple sclerosis and method of treating multiple sclerosis

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2015004436A (en) * 2012-10-09 2015-06-24 Biogen Idec Inc Combination therapies and uses for treatment of demyelinating disorders.
CN106316982B (en) * 2015-06-30 2020-08-14 中国人民解放军军事医学科学院毒物药物研究所 Thiazine amide derivative and use thereof

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6060501A (en) * 1994-06-02 2000-05-09 Schering Aktiengesellschaft Combined treatment of multiple sclerosis

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2509573C2 (en) * 2010-07-27 2014-03-20 Олег Ильич Эпштейн Drug for treating multiple sclerosis and method of treating multiple sclerosis

Also Published As

Publication number Publication date
ZA200505869B (en) 2006-11-29
CN1942161A (en) 2007-04-04
CN1942161B (en) 2012-05-30

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