UA72743C2 - Essentially nonaqueous liquid pharmaceutical concentrate composition containing sertraline, method of using this concentrate, method for treatment - Google Patents
Essentially nonaqueous liquid pharmaceutical concentrate composition containing sertraline, method of using this concentrate, method for treatment Download PDFInfo
- Publication number
- UA72743C2 UA72743C2 UA2001042450A UA2001042450A UA72743C2 UA 72743 C2 UA72743 C2 UA 72743C2 UA 2001042450 A UA2001042450 A UA 2001042450A UA 2001042450 A UA2001042450 A UA 2001042450A UA 72743 C2 UA72743 C2 UA 72743C2
- Authority
- UA
- Ukraine
- Prior art keywords
- sertraline
- concentrate
- ethanol
- aqueous
- menthol
- Prior art date
Links
- 229960002073 sertraline Drugs 0.000 title claims abstract description 78
- VGKDLMBJGBXTGI-SJCJKPOMSA-N sertraline Chemical compound C1([C@@H]2CC[C@@H](C3=CC=CC=C32)NC)=CC=C(Cl)C(Cl)=C1 VGKDLMBJGBXTGI-SJCJKPOMSA-N 0.000 title claims abstract description 78
- 239000012141 concentrate Substances 0.000 title claims abstract description 50
- 239000000203 mixture Substances 0.000 title claims abstract description 40
- 238000000034 method Methods 0.000 title claims abstract description 15
- 239000007788 liquid Substances 0.000 title claims abstract description 7
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims abstract description 15
- 150000003839 salts Chemical class 0.000 claims abstract description 13
- 239000007864 aqueous solution Substances 0.000 claims abstract description 11
- 201000010099 disease Diseases 0.000 claims abstract description 8
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 185
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims description 132
- 235000008504 concentrate Nutrition 0.000 claims description 45
- NOOLISFMXDJSKH-UHFFFAOYSA-N DL-menthol Natural products CC(C)C1CCC(C)CC1O NOOLISFMXDJSKH-UHFFFAOYSA-N 0.000 claims description 41
- 229940041616 menthol Drugs 0.000 claims description 41
- GLQPTZAAUROJMO-UHFFFAOYSA-N 4-(3,4-dimethoxyphenyl)benzaldehyde Chemical compound C1=C(OC)C(OC)=CC=C1C1=CC=C(C=O)C=C1 GLQPTZAAUROJMO-UHFFFAOYSA-N 0.000 claims description 26
- 229960003660 sertraline hydrochloride Drugs 0.000 claims description 26
- NLZUEZXRPGMBCV-UHFFFAOYSA-N Butylhydroxytoluene Chemical compound CC1=CC(C(C)(C)C)=C(O)C(C(C)(C)C)=C1 NLZUEZXRPGMBCV-UHFFFAOYSA-N 0.000 claims description 18
- 239000003755 preservative agent Substances 0.000 claims description 16
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 16
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 claims description 15
- QELSKZZBTMNZEB-UHFFFAOYSA-N propylparaben Chemical compound CCCOC(=O)C1=CC=C(O)C=C1 QELSKZZBTMNZEB-UHFFFAOYSA-N 0.000 claims description 12
- KCXVZYZYPLLWCC-UHFFFAOYSA-N EDTA Chemical compound OC(=O)CN(CC(O)=O)CCN(CC(O)=O)CC(O)=O KCXVZYZYPLLWCC-UHFFFAOYSA-N 0.000 claims description 10
- LXCFILQKKLGQFO-UHFFFAOYSA-N methylparaben Chemical compound COC(=O)C1=CC=C(O)C=C1 LXCFILQKKLGQFO-UHFFFAOYSA-N 0.000 claims description 10
- 244000246386 Mentha pulegium Species 0.000 claims description 9
- 235000016257 Mentha pulegium Nutrition 0.000 claims description 9
- 235000004357 Mentha x piperita Nutrition 0.000 claims description 9
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 claims description 9
- 235000001050 hortel pimenta Nutrition 0.000 claims description 9
- 230000002335 preservative effect Effects 0.000 claims description 9
- ZTHYODDOHIVTJV-UHFFFAOYSA-N Propyl gallate Chemical compound CCCOC(=O)C1=CC(O)=C(O)C(O)=C1 ZTHYODDOHIVTJV-UHFFFAOYSA-N 0.000 claims description 8
- 239000003085 diluting agent Substances 0.000 claims description 8
- 239000000796 flavoring agent Substances 0.000 claims description 8
- 235000013355 food flavoring agent Nutrition 0.000 claims description 8
- 208000035475 disorder Diseases 0.000 claims description 7
- 239000000126 substance Substances 0.000 claims description 7
- 208000019901 Anxiety disease Diseases 0.000 claims description 6
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 claims description 6
- 235000015205 orange juice Nutrition 0.000 claims description 6
- 235000010232 propyl p-hydroxybenzoate Nutrition 0.000 claims description 6
- 239000004405 propyl p-hydroxybenzoate Substances 0.000 claims description 6
- 229960003415 propylparaben Drugs 0.000 claims description 6
- 208000021384 Obsessive-Compulsive disease Diseases 0.000 claims description 5
- CDBYLPFSWZWCQE-UHFFFAOYSA-L Sodium Carbonate Chemical compound [Na+].[Na+].[O-]C([O-])=O CDBYLPFSWZWCQE-UHFFFAOYSA-L 0.000 claims description 5
- 229960004106 citric acid Drugs 0.000 claims description 5
- 238000007865 diluting Methods 0.000 claims description 5
- 235000014080 ginger ale Nutrition 0.000 claims description 5
- 235000019223 lemon-lime Nutrition 0.000 claims description 5
- 235000015122 lemonade Nutrition 0.000 claims description 5
- 235000014666 liquid concentrate Nutrition 0.000 claims description 5
- 235000010270 methyl p-hydroxybenzoate Nutrition 0.000 claims description 5
- 239000004292 methyl p-hydroxybenzoate Substances 0.000 claims description 5
- 229960002216 methylparaben Drugs 0.000 claims description 5
- GSEJCLTVZPLZKY-UHFFFAOYSA-N Triethanolamine Chemical compound OCCN(CCO)CCO GSEJCLTVZPLZKY-UHFFFAOYSA-N 0.000 claims description 4
- 230000036506 anxiety Effects 0.000 claims description 4
- 239000008194 pharmaceutical composition Substances 0.000 claims description 4
- 206010036596 premature ejaculation Diseases 0.000 claims description 4
- 235000010388 propyl gallate Nutrition 0.000 claims description 4
- 239000000473 propyl gallate Substances 0.000 claims description 4
- 229940075579 propyl gallate Drugs 0.000 claims description 4
- 229960004418 trolamine Drugs 0.000 claims description 4
- QAQJMLQRFWZOBN-LAUBAEHRSA-N L-ascorbyl-6-palmitate Chemical compound CCCCCCCCCCCCCCCC(=O)OC[C@H](O)[C@H]1OC(=O)C(O)=C1O QAQJMLQRFWZOBN-LAUBAEHRSA-N 0.000 claims description 3
- 239000011786 L-ascorbyl-6-palmitate Substances 0.000 claims description 3
- DWAQJAXMDSEUJJ-UHFFFAOYSA-M Sodium bisulfite Chemical compound [Na+].OS([O-])=O DWAQJAXMDSEUJJ-UHFFFAOYSA-M 0.000 claims description 3
- 235000010323 ascorbic acid Nutrition 0.000 claims description 3
- 239000011668 ascorbic acid Substances 0.000 claims description 3
- 229960005070 ascorbic acid Drugs 0.000 claims description 3
- 235000010385 ascorbyl palmitate Nutrition 0.000 claims description 3
- 235000018417 cysteine Nutrition 0.000 claims description 3
- XUJNEKJLAYXESH-UHFFFAOYSA-N cysteine Natural products SCC(N)C(O)=O XUJNEKJLAYXESH-UHFFFAOYSA-N 0.000 claims description 3
- PJUIMOJAAPLTRJ-UHFFFAOYSA-N monothioglycerol Chemical compound OCC(O)CS PJUIMOJAAPLTRJ-UHFFFAOYSA-N 0.000 claims description 3
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- 230000000862 serotonergic effect Effects 0.000 claims description 3
- HRZFUMHJMZEROT-UHFFFAOYSA-L sodium disulfite Chemical compound [Na+].[Na+].[O-]S(=O)S([O-])(=O)=O HRZFUMHJMZEROT-UHFFFAOYSA-L 0.000 claims description 3
- 235000010267 sodium hydrogen sulphite Nutrition 0.000 claims description 3
- 229940001584 sodium metabisulfite Drugs 0.000 claims description 3
- 235000010262 sodium metabisulphite Nutrition 0.000 claims description 3
- 229940035024 thioglycerol Drugs 0.000 claims description 3
- 208000011688 Generalised anxiety disease Diseases 0.000 claims description 2
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 claims description 2
- XUJNEKJLAYXESH-REOHCLBHSA-N L-Cysteine Chemical compound SC[C@H](N)C(O)=O XUJNEKJLAYXESH-REOHCLBHSA-N 0.000 claims description 2
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- 235000015424 sodium Nutrition 0.000 claims description 2
- 239000011734 sodium Substances 0.000 claims description 2
- 229910052708 sodium Inorganic materials 0.000 claims description 2
- NOOLISFMXDJSKH-UTLUCORTSA-N (+)-Neomenthol Chemical compound CC(C)[C@@H]1CC[C@@H](C)C[C@@H]1O NOOLISFMXDJSKH-UTLUCORTSA-N 0.000 claims 3
- LHGVFZTZFXWLCP-UHFFFAOYSA-N guaiacol Chemical compound COC1=CC=CC=C1O LHGVFZTZFXWLCP-UHFFFAOYSA-N 0.000 claims 1
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- DHCDFWKWKRSZHF-UHFFFAOYSA-N sulfurothioic S-acid Chemical compound OS(O)(=O)=S DHCDFWKWKRSZHF-UHFFFAOYSA-N 0.000 claims 1
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- 235000011187 glycerol Nutrition 0.000 description 52
- NOOLISFMXDJSKH-KXUCPTDWSA-N (-)-Menthol Chemical compound CC(C)[C@@H]1CC[C@@H](C)C[C@H]1O NOOLISFMXDJSKH-KXUCPTDWSA-N 0.000 description 39
- 239000000243 solution Substances 0.000 description 14
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- 239000003814 drug Substances 0.000 description 11
- AFVFQIVMOAPDHO-UHFFFAOYSA-N Methanesulfonic acid Chemical compound CS(O)(=O)=O AFVFQIVMOAPDHO-UHFFFAOYSA-N 0.000 description 9
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- QCQCHGYLTSGIGX-GHXANHINSA-N 4-[[(3ar,5ar,5br,7ar,9s,11ar,11br,13as)-5a,5b,8,8,11a-pentamethyl-3a-[(5-methylpyridine-3-carbonyl)amino]-2-oxo-1-propan-2-yl-4,5,6,7,7a,9,10,11,11b,12,13,13a-dodecahydro-3h-cyclopenta[a]chrysen-9-yl]oxy]-2,2-dimethyl-4-oxobutanoic acid Chemical compound N([C@@]12CC[C@@]3(C)[C@]4(C)CC[C@H]5C(C)(C)[C@@H](OC(=O)CC(C)(C)C(O)=O)CC[C@]5(C)[C@H]4CC[C@@H]3C1=C(C(C2)=O)C(C)C)C(=O)C1=CN=CC(C)=C1 QCQCHGYLTSGIGX-GHXANHINSA-N 0.000 description 7
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
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- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
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- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
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- A61P25/00—Drugs for disorders of the nervous system
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- A—HUMAN NECESSITIES
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- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Epidemiology (AREA)
- Physical Education & Sports Medicine (AREA)
- Psychiatry (AREA)
- Rheumatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Vascular Medicine (AREA)
- Obesity (AREA)
- Cardiology (AREA)
- Addiction (AREA)
- Urology & Nephrology (AREA)
- Pain & Pain Management (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Nutrition Science (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Child & Adolescent Psychology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10402498P | 1998-10-13 | 1998-10-13 | |
| PCT/IB1999/001571 WO2000021521A2 (en) | 1998-10-13 | 1999-09-22 | Sertraline oral concentrate |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| UA72743C2 true UA72743C2 (en) | 2005-04-15 |
Family
ID=22298286
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| UA2001042450A UA72743C2 (en) | 1998-10-13 | 1999-09-22 | Essentially nonaqueous liquid pharmaceutical concentrate composition containing sertraline, method of using this concentrate, method for treatment |
Country Status (45)
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EE05315B1 (et) | 1999-09-03 | 2010-08-16 | Eli Lilly And Company | Dapoksetiini v?i selle farmatseutiliselt vastuv?etava soola kasutamine ravimi valmistamiseks, mis on ette nhtud imetajal esineva seksuaalse funktsioonihire ravimiseks v?i m?jutamiseks |
| US20030086972A1 (en) * | 2000-08-09 | 2003-05-08 | Appel Leah E. | Hydrogel-driven drug dosage form |
| WO2004065348A1 (en) * | 2003-01-23 | 2004-08-05 | Pfizer Products Inc. | Pharmaceutically acceptable salts of sertraline and pharmaceutical compositions thereof |
| WO2005000786A1 (en) * | 2003-05-23 | 2005-01-06 | Transform Pharmaceuticals, Inc. | Sertraline compositions |
| WO2005034910A1 (en) * | 2003-10-08 | 2005-04-21 | Ranbaxy Laboratories Limited | Oral liquid pharmaceutical compositions of sertraline |
| WO2007052152A2 (en) * | 2005-11-07 | 2007-05-10 | Aurobindo Pharma Limited | Sertraline oral concentrate |
| WO2008112641A2 (en) * | 2007-03-09 | 2008-09-18 | New York University | Methods and compositions for treating thalamocortical dysrhythmia |
| CN109908354A (zh) * | 2017-12-12 | 2019-06-21 | 万特制药(海南)有限公司 | 盐酸舍曲林口服浓缩液及其制备工艺 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4536518A (en) * | 1979-11-01 | 1985-08-20 | Pfizer Inc. | Antidepressant derivatives of cis-4-phenyl-1,2,3,4-tetrahydro-1-naphthalenamine |
| US5130338A (en) * | 1989-08-30 | 1992-07-14 | Pfizer Inc. | Method of treating chemical dependencies using sertraline |
| DE69004529T2 (de) * | 1989-08-30 | 1994-02-24 | Pfizer | Verwendung von Sertralin zur Behandlung von Abhängigkeiten von chemischen Stoffen. |
| US4940731A (en) * | 1989-08-30 | 1990-07-10 | Pfizer Inc. | Method of treating premature ejaculation using sertraline |
| US4962128A (en) * | 1989-11-02 | 1990-10-09 | Pfizer Inc. | Method of treating anxiety-related disorders using sertraline |
| CA2143070C (en) * | 1994-02-22 | 2001-12-18 | Pankaj Modi | Oral controlled release liquid suspension pharmaceutical formulation |
| US5597826A (en) * | 1994-09-14 | 1997-01-28 | Pfizer Inc. | Compositions containing sertraline and a 5-HT1D receptor agonist or antagonist |
| SE508372C2 (sv) * | 1995-02-13 | 1998-09-28 | Kjell Lindstroem | Metod och utrustning för tillförsel eller aspiration av substanser inom gastrointestinalkanalen, avsedd för mätning av farmakokinetiska och fysikalisk-kemiska parametrar |
| DK0768083T3 (da) * | 1995-07-17 | 2003-06-23 | Pfizer | Anvendelse af sertralin til at behandle patienter med post myocardisk infarkt |
| AU724635B2 (en) * | 1997-07-01 | 2000-09-28 | Pfizer Products Inc. | Gelatine encapsulated solution dosage forms of sertraline |
-
1999
- 1999-09-22 WO PCT/IB1999/001571 patent/WO2000021521A2/en active IP Right Grant
- 1999-09-22 EE EEP200100221A patent/EE04868B1/xx not_active IP Right Cessation
- 1999-09-22 KR KR10-2001-7004559A patent/KR100417200B1/ko not_active IP Right Cessation
- 1999-09-22 AT AT99943168T patent/ATE254453T1/de not_active IP Right Cessation
- 1999-09-22 SK SK458-2001A patent/SK4582001A3/sk unknown
- 1999-09-22 ES ES99943168T patent/ES2209490T3/es not_active Expired - Lifetime
- 1999-09-22 EA EA200100285A patent/EA003990B1/ru not_active IP Right Cessation
- 1999-09-22 YU YU26401A patent/YU26401A/sh unknown
- 1999-09-22 OA OA1200100087A patent/OA11662A/en unknown
- 1999-09-22 DK DK99943168T patent/DK1121107T3/da active
- 1999-09-22 JP JP2000575497A patent/JP3792514B2/ja not_active Expired - Fee Related
- 1999-09-22 TR TR2001/01090T patent/TR200101090T2/xx unknown
- 1999-09-22 AP APAP/P/2001/002119A patent/AP2001002119A0/en unknown
- 1999-09-22 CZ CZ20011286A patent/CZ20011286A3/cs unknown
- 1999-09-22 PT PT99943168T patent/PT1121107E/pt unknown
- 1999-09-22 PL PL99348119A patent/PL348119A1/xx not_active Application Discontinuation
- 1999-09-22 DE DE69912978T patent/DE69912978T2/de not_active Expired - Fee Related
- 1999-09-22 ID IDW20010824A patent/ID29845A/id unknown
- 1999-09-22 UA UA2001042450A patent/UA72743C2/uk unknown
- 1999-09-22 AU AU56436/99A patent/AU766202B2/en not_active Ceased
- 1999-09-22 EP EP99943168A patent/EP1121107B1/en not_active Expired - Lifetime
- 1999-09-22 NZ NZ510756A patent/NZ510756A/en unknown
- 1999-09-22 CN CNB998120871A patent/CN1184962C/zh not_active Expired - Fee Related
- 1999-09-22 HU HU0104470A patent/HUP0104470A3/hu unknown
- 1999-09-22 CA CA002346335A patent/CA2346335C/en not_active Expired - Fee Related
- 1999-09-22 GE GEAP19995852A patent/GEP20032969B/en unknown
- 1999-09-22 BR BR9914418-2A patent/BR9914418A/pt not_active Application Discontinuation
- 1999-09-28 PA PA19998483301A patent/PA8483301A1/es unknown
- 1999-10-05 GT GT199900171A patent/GT199900171A/es unknown
- 1999-10-06 TW TW088117244A patent/TWI228043B/zh not_active IP Right Cessation
- 1999-10-08 AR ARP990105116A patent/AR014082A1/es unknown
- 1999-10-09 GC GCP1999314 patent/GC0000175A/en active
- 1999-10-11 MY MYPI99004384A patent/MY122477A/en unknown
- 1999-10-11 PE PE1999001025A patent/PE20001108A1/es not_active Application Discontinuation
- 1999-10-12 EG EG127599A patent/EG23818A/xx active
- 1999-10-12 MA MA25814A patent/MA26698A1/fr unknown
- 1999-10-12 TN TNTNSN99190A patent/TNSN99190A1/fr unknown
- 1999-10-12 DZ DZ990213A patent/DZ2913A1/xx active
- 1999-10-13 CO CO99065089A patent/CO5150213A1/es unknown
-
2001
- 2001-03-23 IS IS5906A patent/IS2239B/is unknown
- 2001-04-09 ZA ZA200102900A patent/ZA200102900B/xx unknown
- 2001-04-10 HR HR20010263A patent/HRP20010263B1/xx not_active IP Right Cessation
- 2001-04-10 NO NO20011829A patent/NO20011829L/no not_active Application Discontinuation
- 2001-04-10 BG BG105434A patent/BG65085B1/bg unknown
-
2002
- 2002-03-14 HK HK02101974.6A patent/HK1040199B/zh not_active IP Right Cessation
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