UA65243A - Method for treating infected wounds in dogs - Google Patents

Abstract

The method for treating the infected wounds in the dogs provides for treating the surgery field with the disinfectant solution, anesthetizing the area of the wound with 0.5% lidocaine solution, cleaning the wound mechanically, ensuring the exudate outflow, rinsing the wound with hydrogen peroxide. The broad spectrum antibiotic and 10% zinc ointment are finally used. Two different dosage forms of Ofloxacin are used once a day: 0.1% aqueous solution and Ofloderm ointment.

Description

The invention belongs to the field of veterinary medicine, in particular to veterinary surgery, namely to methods of treating infected wounds of various etiologies and can be used to treat dogs with this pathology.

A known method of treating wounds in dogs, which includes: primary treatment of damaged tissues, washing the wounds with 395 hydrogen peroxide solution, drying with a sterile tampon and powdering the wounds with chlortetracycline powder (in the first phase of the wound process) and applying a bandage impregnated with 1 905 chlortetracycline ointment ( in the second phase of the wound process). If necessary, pockets and bays are dissected to remove purulent exudate. |Veremei Z.I., Elisezv A.N., Lukyanovsky V.A. Handbook on the use of medicinal products in veterinary surgery. -Minsk "Harvest". -1989.|.

The disadvantage of the method is that the therapeutic effect is manifested only on 21-26 days.

There is also a well-known method of treating wounds with medicinal forms of plant origin, which consists in primary treatment of the skin and damaged tissues with the subsequent use of St. John's wort oil and 1095 propolis ointment (Natalia Avraamenko, Volodymyr Nagornyi. Non-traditional methods of wound treatment. "Veterinary Medicine

of Ukraine". 1999.-p.31-32)

Complete healing of wounds in calves treated with St. John's wort oil and 1095th propolis ointment is observed on the 18th day.

Such a period of wound treatment is long-term, although the cost of medicine is insignificant.

A complex method of wound treatment, which combines surgical and drug therapy, is also known. (Yuri

Myronenko. Treatment of wounds in dogs and cats. /Veterinary Medicine of Ukraine. - 2001.-Me3,-p.42-43//) This method of wound treatment offers the use of various medicinal forms depending on the phase of the wound process, namely: primary treatment of wounds and the use of levomycol or levosyn ointments in the 1st phase of the wound process; in the 2nd phase - after applying converging seams, vinyl or vundehil ointment.

The disadvantage of this method of treatment is the use of many ointments and the high cost of their purchase.

The closest in essence to the claimed method is the method by M.V. Plahotyn. Handbook of veterinary surgery. -Moscow "Kolos".-1977, p.36-46Y, which includes: initial treatment of wounds, washing them with 395 hydrogen peroxide solution, dusting with chlortetracycline powder (in the first phase of the wound process) and applying a bandage impregnated with 195 chlortetracycline ointment (in the second phase of the wound process).

The disadvantage of this method of treatment is the long recovery period of animals, which reaches an average of 24 days.

The method of wound treatment proposed by us eliminates the shortcomings of the prototype and ensures full and stable recovery of sick animals, which were treated seven days faster, compared to the prototype.

The invention is based on the task of developing an effective and affordable method of treating infected wounds in dogs, which is cost-effective and convenient to use.

The technical result is achieved by using the broad-spectrum antibiotic - ofloxacin in various dosage forms - 0.195 aqueous solution and 0.590 Ofloderm ointment, which also includes the antibiotic ofloxacin.

Moreover, 0.195 aqueous solution of ofloxacin is used when changing the bandage (irrigation of wounds in the first phase of the wound process); 0.596 ointment "Ofloderm" is applied in a thin layer once a day during the first five days of treatment of sick animals (in the second phase of the wound process).

Ofloxacin is an antibiotic of the fluoroquinolone group, which is characterized by a wide spectrum of antimicrobial action, high bactericidal activity and good pharmacokinetics, which allows them to be used for the treatment of infections of various localization.

Fluoroquinolones, which include the antibiotic ofloxacin, are active against gram-negative and gram-positive aerobic bacteria, including E. soya, Zpidepa spp., Zaitopeia spp., Epiegorasieg spp., Kiervsivya 5pp., Rgoiviv spp., Zetaia 5pp., Rgomidepsia 5 years.

Meizzetia yr., RazieshgeiiPa 5yr., Rzendotopaz yr..I ediopeia yr.

Z.eridegtiaiv, 5. ashgeizv, 5. biodepev.

Streptococci, staphylococci, Proteus, and Pseudomonas aeruginosa were isolated from infected wounds of sick animals.

The conducted studies proved that ofloxacin in various forms suppresses the growth of anaerobic bacteria and does not lose its activity in the presence of purulent masses. 0.195 aqueous solution of ofloxacin is used in the first phase of the wound process to destroy secondary microflora. 0.595 "Ofloderm" ointment, which contains the antibiotic ofloxacin, improves regenerative processes and prevents the development of secondary infection.

The use of ofloxacin in different dosage forms was taken into account depending on the specifics of the stages of the wound process.

During the patent information search, the applicant found a technical solution / M.V. Plahotyn.

Handbook of veterinary surgery. Moscow "Colossus", 1977 p. 36-40/, which contains the largest number of essential features common to the claimed method: treatment of the operating field with a disinfectant, anesthesia with a 0.590 solution of lidocaine, mechanical cleaning of the wound and ensuring the outflow of wound exudate, washing the wound with hydrogen peroxide, the use of a broad-spectrum antibiotic and at the end at the stage of application of 10905 zinc ointment. However, the presence of the specified features common to the prototype is not sufficient to obtain the technical result provided by the claimed method. No technical solutions were identified that would fully match the set of features with the stated ones. This allows us to draw a conclusion about the compliance of the declared technical solution with the "novelty" criterion of the invention. In the patent and scientific and technical information, no technical solutions were found, in which there were 6 described information about the features that distinguish the claimed method from the prototype and ensure the achievement of a technical result: for the treatment of wounds, the antibiotic ofloxacin is used simultaneously in two dosage forms -0.195 aqueous solution for washing and "Ofloderm" ointment for application to the wound surface.

The claimed invention relates to the field of veterinary medicine, in particular veterinary surgery, namely to methods of treating infected wounds in dogs and can be applied both in individual farms and enterprises with different forms of ownership that keep dogs, and therefore meets the criterion of the invention "industrial applicability ".

The claimed method is carried out as follows:

Sick dogs with infected wounds are treated in the following sequence, using generally accepted methods.

Before treatment, a thorough examination of the general condition of the dogs and the local pathological process must be carried out, namely: determination of the animal's body temperature; determination of respiratory movements; determination of pulse; the degree of damage to the affected tissues; the presence of foreign bodies at the site of injury; establishing the phase of the wound process.

Primary surgical treatment of damaged tissues is carried out.

After anesthesia with 0.595 lidocaine solution, dead and non-viable tissues, blood clots and foreign bodies are removed from the wounds.

To ensure the outflow of purulent exudate, pockets and bays are dissected, after which the wounds are washed with 395% hydrogen peroxide solution and dried with a sterile swab.

Further treatment is carried out taking into account the pathogenesis and the phase of the wound process, namely: the wounds are washed with a 0.195 aqueous solution of ofloxacin and a thin layer of the proposed Ofloderm ointment is applied to the surface of the wound once a day and a bandage is applied. The bandage is changed every other day until the granulation processes are complete.

At the final stage of wound healing, 1095 zinc ointment is applied once a day.

The effectiveness of the claimed method and its advantage in comparison with the prototype was studied for 3 years on dogs admitted to the clinic of the Department of Surgery of the LDAVM in S.3. Gzytsky in the period from 2000-2003.

Experiments were conducted on 26 dogs of different breeds, aged 2-9 years, weighing 20-60 kg, with infected wounds.

All animals belonged to the owners and were kept at home. As the animals entered the clinic, the dogs were conventionally divided into two groups - control (prototype) and experimental (new method), each with 13 dogs with a similar pathology. Observations obtained during treatment are presented in tables 1, 2.

Table 1

Scheme of treatment of dogs with infected wounds (prototype method) 2. Use of medicinal products: 590 alcohol solution of iodine; x x 0.590 lidocaine solution; x x 395 hydrogen peroxide solution. Хх Х и но что 0.196 aqueous solution 3. Use of medicinal products: chlortetracycline powder; ! ofloxacin;

I o, 195 xdortetracycline ointment 0.596 "Ofloderm" ointment /one zinc ointment 10905. X X

Table 2

Dynamics of the course of the wound process in the treatment of dogs with purulent wounds with different methods of treatment

Types of random K-ty Complete healing of animals Group of animals Occurrence Beginning of purulent wounds of animals | Cleansing wounds not pf wounds

Cleaning of wounds ranulatsi | Epithelization.

Anne of the Virgin Wounds

So, the data presented in the table confirm the undeniable advantage of the claimed method of treating infected wounds in dogs, compared to the prototype.

In general, the healing process of wounds when treated according to the new method lasts 17 days, and when treated according to the prototype - 24 days.

The method eliminates the possibility of relapses and ensures 10095 recovery of treated animals.

Claims (1)

The method of treating infected wounds in dogs, which includes treatment of the operative field with a disinfectant, analgesia with a 0.595 solution of lidocaine, mechanical cleaning of wounds, ensuring the outflow of wound exudate, washing the wounds with hydrogen peroxide, the use of a broad-spectrum antibiotic, and at the final stage of treatment - 107o zinc ointment, which differs in that the antibiotic ofloxacin is used simultaneously in two dosage forms once a day: the wound is washed with a 0.190 aqueous solution of ofloxacin, and "Ofloderm" ointment is applied to the wound in a thin layer.