UA58220C2 - Solid dosage form of terbinafin hydrochloride - Google Patents
Solid dosage form of terbinafin hydrochloride Download PDFInfo
- Publication number
- UA58220C2 UA58220C2 UA2002108596A UA2002108596A UA58220C2 UA 58220 C2 UA58220 C2 UA 58220C2 UA 2002108596 A UA2002108596 A UA 2002108596A UA 2002108596 A UA2002108596 A UA 2002108596A UA 58220 C2 UA58220 C2 UA 58220C2
- Authority
- UA
- Ukraine
- Prior art keywords
- kolydon
- dosage form
- solid dosage
- microcrystalline cellulose
- benzoic acid
- Prior art date
Links
- DOMXUEMWDBAQBQ-WEVVVXLNSA-N terbinafine Chemical compound C1=CC=C2C(CN(C\C=C\C#CC(C)(C)C)C)=CC=CC2=C1 DOMXUEMWDBAQBQ-WEVVVXLNSA-N 0.000 title abstract description 14
- 239000007909 solid dosage form Substances 0.000 title abstract description 3
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 title abstract 2
- WPYMKLBDIGXBTP-UHFFFAOYSA-N Benzoic acid Natural products OC(=O)C1=CC=CC=C1 WPYMKLBDIGXBTP-UHFFFAOYSA-N 0.000 abstract description 16
- HQKMJHAJHXVSDF-UHFFFAOYSA-L magnesium stearate Chemical compound [Mg+2].CCCCCCCCCCCCCCCCCC([O-])=O.CCCCCCCCCCCCCCCCCC([O-])=O HQKMJHAJHXVSDF-UHFFFAOYSA-L 0.000 abstract description 16
- 229920000168 Microcrystalline cellulose Polymers 0.000 abstract description 9
- 235000019813 microcrystalline cellulose Nutrition 0.000 abstract description 9
- 239000008108 microcrystalline cellulose Substances 0.000 abstract description 9
- 229940016286 microcrystalline cellulose Drugs 0.000 abstract description 9
- 239000005711 Benzoic acid Substances 0.000 abstract description 8
- 235000010233 benzoic acid Nutrition 0.000 abstract description 8
- 235000019359 magnesium stearate Nutrition 0.000 abstract description 8
- 239000000443 aerosol Substances 0.000 abstract description 7
- WXMKPNITSTVMEF-UHFFFAOYSA-M sodium benzoate Chemical compound [Na+].[O-]C(=O)C1=CC=CC=C1 WXMKPNITSTVMEF-UHFFFAOYSA-M 0.000 abstract description 3
- 235000010234 sodium benzoate Nutrition 0.000 abstract description 3
- 239000004299 sodium benzoate Substances 0.000 abstract description 3
- 239000007864 aqueous solution Substances 0.000 abstract description 2
- 239000003795 chemical substances by application Substances 0.000 abstract 2
- 238000000227 grinding Methods 0.000 abstract 2
- 239000000546 pharmaceutical excipient Substances 0.000 abstract 2
- 239000000080 wetting agent Substances 0.000 abstract 2
- 239000013543 active substance Substances 0.000 abstract 1
- WXBLLCUINBKULX-UHFFFAOYSA-N benzoic acid Chemical compound OC(=O)C1=CC=CC=C1.OC(=O)C1=CC=CC=C1 WXBLLCUINBKULX-UHFFFAOYSA-N 0.000 abstract 1
- 239000003755 preservative agent Substances 0.000 abstract 1
- 229960000699 terbinafine hydrochloride Drugs 0.000 description 10
- 239000004615 ingredient Substances 0.000 description 8
- 239000003814 drug Substances 0.000 description 5
- 229940079593 drug Drugs 0.000 description 5
- 239000008187 granular material Substances 0.000 description 4
- 230000002906 microbiologic effect Effects 0.000 description 3
- 244000005700 microbiome Species 0.000 description 3
- 230000000845 anti-microbial effect Effects 0.000 description 2
- 235000015097 nutrients Nutrition 0.000 description 2
- 208000012766 Growth delay Diseases 0.000 description 1
- FYYHWMGAXLPEAU-UHFFFAOYSA-N Magnesium Chemical compound [Mg] FYYHWMGAXLPEAU-UHFFFAOYSA-N 0.000 description 1
- 230000015556 catabolic process Effects 0.000 description 1
- 239000001913 cellulose Substances 0.000 description 1
- 235000010980 cellulose Nutrition 0.000 description 1
- 229920002678 cellulose Polymers 0.000 description 1
- 230000003247 decreasing effect Effects 0.000 description 1
- 239000012895 dilution Substances 0.000 description 1
- 238000010790 dilution Methods 0.000 description 1
- 239000002552 dosage form Substances 0.000 description 1
- 238000004128 high performance liquid chromatography Methods 0.000 description 1
- 239000012535 impurity Substances 0.000 description 1
- 229940089474 lamisil Drugs 0.000 description 1
- 239000011777 magnesium Substances 0.000 description 1
- 229910052749 magnesium Inorganic materials 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- -1 methylhydroxypropyl Chemical group 0.000 description 1
- 239000002994 raw material Substances 0.000 description 1
- 150000003385 sodium Chemical class 0.000 description 1
- 229940080313 sodium starch Drugs 0.000 description 1
- 238000009331 sowing Methods 0.000 description 1
- 229960002722 terbinafine Drugs 0.000 description 1
- 238000011287 therapeutic dose Methods 0.000 description 1
Landscapes
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| RU2001129798A RU2200003C1 (ru) | 2001-11-08 | 2001-11-08 | Твердая лекарственная форма тербинафина гидрохлорида |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| UA58220C2 true UA58220C2 (en) | 2005-05-16 |
Family
ID=20254134
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| UA2002108596A UA58220C2 (en) | 2001-11-08 | 2002-10-29 | Solid dosage form of terbinafin hydrochloride |
Country Status (4)
| Country | Link |
|---|---|
| EA (1) | EA004105B1 (ru) |
| GE (1) | GEP20043353B (ru) |
| RU (1) | RU2200003C1 (ru) |
| UA (1) | UA58220C2 (ru) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN116139093A (zh) * | 2022-12-28 | 2023-05-23 | 南京臣功制药股份有限公司 | 一种包含盐酸特比萘芬的速释片剂组合物及其制备工艺 |
-
2001
- 2001-11-08 RU RU2001129798A patent/RU2200003C1/ru not_active IP Right Cessation
-
2002
- 2002-10-28 GE GEAP2002004967 patent/GEP20043353B/en unknown
- 2002-10-29 UA UA2002108596A patent/UA58220C2/uk unknown
- 2002-11-04 EA EA200201064A patent/EA004105B1/ru not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| EA004105B1 (ru) | 2003-12-25 |
| EA200201064A2 (ru) | 2003-06-26 |
| RU2200003C1 (ru) | 2003-03-10 |
| GEP20043353B (en) | 2004-05-10 |
| EA200201064A3 (ru) | 2003-08-28 |
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