UA39852C2 - PHARMACEUTICAL COMPOSITION FOR TREATMENT OF HYPERLIPOPROTEINEMIA AND ATHEROSCLEROSIS - Google Patents

PHARMACEUTICAL COMPOSITION FOR TREATMENT OF HYPERLIPOPROTEINEMIA AND ATHEROSCLEROSIS

Info

Publication number
UA39852C2
UA39852C2 UA93003094A UA93003094A UA39852C2 UA 39852 C2 UA39852 C2 UA 39852C2 UA 93003094 A UA93003094 A UA 93003094A UA 93003094 A UA93003094 A UA 93003094A UA 39852 C2 UA39852 C2 UA 39852C2
Authority
UA
Ukraine
Prior art keywords
motor
electric
cavity
electric pump
rotor
Prior art date
Application number
UA93003094A
Other languages
Ukrainian (uk)
Inventor
Мохан Балахандра Кабаді
Річард Віктор Вівілеччіа
Original Assignee
Новартіс Аг
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Новартіс Аг filed Critical Новартіс Аг
Publication of UA39852C2 publication Critical patent/UA39852C2/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A61K31/341—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide not condensed with another ring, e.g. ranitidine, furosemide, bufetolol, muscarine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
    • A61K31/381—Heterocyclic compounds having sulfur as a ring hetero atom having five-membered rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404—Indoles, e.g. pindolol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/50—Pyridazines; Hydrogenated pyridazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics

Abstract

Заглибний електронасос стосується продукції машинобудування, зокрема агрегатів для подачі продуктів, обладнаних відцентровими електронасосами. Заглибний електронасос містить корпус 1, в якому розташований відцентровий насос 2 з електродвигуном 3, що містить водозахищений статор 4 і ротор 5. Порожнина електродвигуна 3 заповнена сумішшю, компонентами якої є вода з упорядкованою молекулярною структурою і необроблений гліцерин, при співвідношенні "гліцерин-вода" в межах від 0,4:0,6 до 0,6:0,4. Електродвигун 3 містить також компенсаційну камеру 7, розташовану з боку хвостової частини вала 8 ротора 5, яка сполучена з порожниною електродвигуна через систему каналів 9'-9". Компенсаційна камера 7 призначена для збирання зазначеної суміші, що витікає з порожнини електродвигуна 3. Така конструкція дозволяє відвернути перегрівання і підвищити рівень вибухозахищеності електронасоса. Зворотний клапан на виході насоса забезпечую сприятливі умови для роботи електронасоса при понижених температурах навколишнього середовища, у результаті чого підвищується загальна надійність електронасоса.Submersible electric pump refers to the products of mechanical engineering, in particular units for supplying products equipped with centrifugal electric pumps. The submersible electric pump comprises a housing 1 which houses a centrifugal pump 2 with an electric motor 3 containing a waterproof stator 4 and a rotor 5. The cavity of the electric motor 3 is filled with a mixture of components of which water is of ordered molecular structure and untreated glycerol, at a ratio of water "g". in the range from 0.4: 0.6 to 0.6: 0.4. The motor 3 also contains a compensation chamber 7 located on the side of the tail portion of the shaft 8 of the rotor 5, which is connected to the cavity of the motor through the channel system 9'-9 ". The compensation chamber 7 is intended for collecting the specified mixture emerging from the cavity of the motor 3. This construction allows to prevent overheating and increase the level of explosion protection of the electric pump. On increasing the overall reliability of the electric pump.

UA93003094A 1991-12-12 1993-06-18 PHARMACEUTICAL COMPOSITION FOR TREATMENT OF HYPERLIPOPROTEINEMIA AND ATHEROSCLEROSIS UA39852C2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US80566791A 1991-12-12 1991-12-12

Publications (1)

Publication Number Publication Date
UA39852C2 true UA39852C2 (en) 2001-07-16

Family

ID=40794725

Family Applications (1)

Application Number Title Priority Date Filing Date
UA93003094A UA39852C2 (en) 1991-12-12 1993-06-18 PHARMACEUTICAL COMPOSITION FOR TREATMENT OF HYPERLIPOPROTEINEMIA AND ATHEROSCLEROSIS

Country Status (8)

Country Link
AT (1) AT401872B (en)
DE (1) DE4245089B4 (en)
HU (1) HU221849B1 (en)
MY (1) MY108187A (en)
NZ (1) NZ270729A (en)
SA (1) SA93130414B1 (en)
TW (1) TW221377B (en)
UA (1) UA39852C2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6242003B1 (en) * 2000-04-13 2001-06-05 Novartis Ag Organic compounds

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5030447A (en) * 1988-03-31 1991-07-09 E. R. Squibb & Sons, Inc. Pharmaceutical compositions having good stability

Also Published As

Publication number Publication date
ATA190595A (en) 1996-05-15
HU0000790D0 (en) 2000-04-28
HU221849B1 (en) 2003-02-28
SA93130414B1 (en) 2004-08-14
AT401872B (en) 1996-12-27
TW221377B (en) 1994-03-01
DE4245089B4 (en) 2009-07-30
NZ270729A (en) 1995-11-27
MY108187A (en) 1996-08-30

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