UA135058U - METHOD OF BIOPHORESIS OF WOUND SURFACES BY VITAMIN B8 BY AEROGEL BANDINGS WITH ZIRCONIUM HEMISPHERE - Google Patents

Abstract

The method of biophoresis of wound surfaces with vitamin B8 involves the application to the wound of two electrodes of dissimilar metals, which are connected by an electrical conductor, which causes a unidirectional circular motion of electrons and there is a constant galvanic current of 5-80 μA. An airgel bandage (based on amorphous silicon dioxide) with zirconium hemispheres containing silicone tubes inside, through which vitamin B8 is injected, is applied to the wound surface.

Description

The useful model belongs to the field of medicine, namely to general surgery, combustiology, traumatology, polytrauma, and can be used for the purpose of adapting a skin graft on a wound bed, as well as in the treatment of wound defects with damage to the skin and underlying tissues.

The known method is as follows: for the purpose of biophoresis, two electrodes made of dissimilar metals are applied to the affected limb or part of the body and connected by an electrical conductor, which causes a unidirectional circular movement of electrons and a constant galvanic current with a strength of 5-80 μA appears. The current ionizes liquid therapeutic substances, gives the ions unidirectional movement, which is used for therapeutic purposes (1-2.

The disadvantage of the known method is the impossibility of controlling the dosage of the medicinal substance, namely the preparation of vitamin VU directly during the process of biophoresis of the wound surface, and the wound dressing does not provide optimal pressure on the wound. When applying a gauze bandage, it is impossible to qualitatively fill the entire wound surface, repeating its relief, and it is also impossible to introduce the therapeutic agent, vitamin VO, into the wound directly without removing the gauze bandage, and the wound bandage does not provide constant antiseptic conditions.

The basis of a useful model is the task of getting rid of the above shortcomings.

The task is solved in the method of biophoresis of wound surfaces, which includes applying to the wound two electrodes made of dissimilar metals, which are connected by an electrical conductor, which causes a unidirectional circular movement of electrons and a constant galvanic current with a strength of 5-80 μA appears, according to a useful model, an airgel bandage (based on amorphous silicon dioxide) with zirconium hemispheres, containing silicone tubes inside, through which vitamin B8 is injected, is applied to the wound surface.

Airgel (based on amorphous silicon dioxide) is a unique material - a gel in which the liquid phase is completely replaced by a gaseous one. This material has a record low density and exhibits a number of unique properties: hardness, transparency, heat resistance, etc. Airgel belongs to the class of mesoporous materials, with the structure of a tree-like network of nanoparticles 2-5 nm in size and pores up to 100 nm in size combined into clusters (I3-6). Also, aerogels have good thermal insulation and hygroscopic properties, they are transparent and through them the state of the wound bed and the features of the wound process are clearly visible. Silicone tubes (through which they are introduced

zo therapeutic agents) are located in the thickness of the airgel bandage, they have one external outlet on the surface of the bandage and pores in its base, from where vitamin B gradually enters the wound.

The use of vitamin B stimulates metabolic and regenerative processes in the wound, reduces the intensity of the inflammatory process. Which, in turn, improves microcirculation in the tissues and shortens the course of the phases of the wound process, prevents over-drying of the wound I7-9|. And the zirconium hemispheres, which are in the airgel bandage, provide constant antiseptic conditions for the wound surfaces.

The method is carried out as follows: wound defects are first treated with dry sterile napkins, maximally adsorbing the wound contents, then the wound is treated with sterile napkins moistened with an aqueous solution of chlorhexidine. After treatment of wound defects, the wound is covered with a sterile napkin and an airgel bandage based on amorphous silicon dioxide with zirconium hemispheres is placed on top of it. A medical substance, namely vitamin B8, is injected directly into the silicone tubes of the airgel bandage. After the introduction of vitamin B8 into silicone tubes, one tube remains connected to the syringe, and the other is closed with a stopper. An electrode (anode) is placed on top of the plate.

During biophoresis, the anode (positive electrode) is placed over the wound defects, and the cathode (negative electrode) is placed under the affected area (extremity) or on the opposite side of the anode.

The strength of the current acting on wound defects is from 5 to 80 μA, the current ionizes vitamin B8, gives ions unidirectional movement into the wound for therapeutic purposes. Without stopping the treatment procedure of biophoresis, after the end of vitamin BV, you can wash the wound surface with an antiseptic solution, injecting it with a syringe through a silicone tube into an airgel bandage, removing the cap before that. Under the action of galvanic current, part of the drug will fall directly to the wound surface through the pores in the lower surface, and part will leave the cavity of the plate through the outlet tube.

So, the method of biophoresis of wound surfaces with vitamin B8 airgel bandages based on amorphous silicon dioxide enables control over its introduction during the wound galvanization procedure, and, if necessary, allows increasing the dose of the drug directly during the procedure. The method improves the deposition of antiseptic and vitamin B8 in the wound tissues, stimulates microcirculation in the affected tissues, reduces microbial contamination of secretions from the wound, and zirconium hemispheres create permanent antiseptic conditions in the wound, which allows to shorten the patient's stay in hospital treatment.

Sources of information: 1. Lisovska T.V., Husakivska O.V. Biophoresis and biopuncture of biological medicine preparations as an alternative to traditional treatment of chronic endometritis // Ukrainian medical almanac. - 2012. - Volume 15, Issue 6. - P. 107-108. 2. pEr/Llymligavviiz ru/ik/radez/eIesihorpogeviv.pPiti

Z. Ma, N.5.; Rhemovi, U.N.; Ushiyep, A. ZANegeg, SOM. Aotrshieg zitshayop oi teApNapilaiYi zi Ashte-rgorepu geiIayopz5pir oi aegode!5. U. Mop-Aguzi. ZoiiAv 2001, 285, 216-221. 4. Ettepipou, A.; EpAKe, 9U. Зааііпу ргорепіе5 апА вигіАіШге ой аегоде!в5. in. 5o0oI-Se! 5AI.

TeApNpoi. 1997,8,781-788. 5. pOrz lim. vrgipdegrgoiezziopa!.Av/ep/hemivm-oi-aegode!-bazeA-taiegia!5-ip-biotelAiAai!- arriiAayop5/11742122 b. pprz//lmlum.tAri.Aot/oigpai/de!5/5redia! from 5ycez/aegodei. 7. pEbrv5 //useozuya. tsalirgagu/biopitiApa-goI-myatipim-ia-miatiporoAiBpin-5roiShk-432.piti. 8. Gubsky Yu. I. Biological chemistry: Textbook. Kyiv-Ternopil: Ukrmedknyga, 2000. - 508 p. 9. per://teAiA!yv5.yAo2.peyipAeh/lAii romia2gok/0-24.

Claims (1)

USEFUL MODEL FORMULA The method of biophoresis of wound surfaces with vitamin B8, which includes applying two electrodes of 3 dissimilar metals to the wound, which are connected by an electrical conductor, which causes a unidirectional circular movement of electrons and a constant galvanic current with a strength of 5-80 μA appears, which is distinguished by the fact that on the wound an airgel bandage (based on amorphous silicon dioxide) with zirconium hemispheres containing silicone tubes inside, through which vitamin B8 is injected, is applied to the surface.