UA135062U - METHOD OF BIOPHORESIS OF WOUND SURFACES BY VITAMIN B10 BY AEROGEL BANDINGS WITH ZIRCONIUM HEMISPHERE - Google Patents

Abstract

The method of biophoresis of wound surfaces with vitamin B10 aerogel dressings based on amorphous silicon dioxide is that two electrodes of dissimilar metals are applied to the wound, which are connected by an electrical conductor, the action of which causes unidirectional circular motion of electrons and is a constant galvanic current. 5-80 μA. An airgel bandage (based on amorphous silicon dioxide) with zirconium hemispheres is placed on the wound surface, containing silicone tubes inside, through which vitamin B10 is injected.

Description

The useful model belongs to medicine, namely to general surgery, combustiology, traumatology, polytrauma, and can be used for the purpose of adapting a skin graft on a wound bed, as well as in the treatment of wound defects with damage to the skin and underlying tissues.

The known method is as follows: for the purpose of biophoresis, two electrodes made of dissimilar metals are applied to the affected limb or part of the body and connected by an electrical conductor, which causes a unidirectional circular movement of electrons and a constant galvanic current with a strength of 5-80 μA appears. The current ionizes liquid medicinal substances, gives ions unidirectional movement, which is used for therapeutic purposes |1-2|.

The disadvantage of the known method is the impossibility of controlling the dosage of the medicinal substance, namely vitamin B1O0 prepatate directly during the process of biophoresis of the wound surface, and the wound dressing does not provide optimal pressure on the wound. When applying a gauze bandage, it is impossible to qualitatively fill the entire wound surface, repeating its relief, and it is also impossible to introduce the therapeutic agent, vitamin BTO, into the wound directly, without removing the gauze bandage, and the wound bandage does not provide constant antiseptic conditions.

The disadvantages of the known method are solved by using, during biophoresis of wound surfaces, an airgel bandage (based on amorphous silicon dioxide) with zirconium hemispheres, which contains silicone tubes for the introduction of a therapeutic medium, vitamin B10, both during and after the therapeutic procedure.

Airgel (based on amorphous silicon dioxide) is a unique material - a gel in which the liquid phase is completely replaced by a gaseous one. This material has a record low density and exhibits a number of unique properties: hardness, transparency, heat resistance, etc. Airgel belongs to the class of mesoporous materials, with the structure of a tree-like network of nanoparticles 2-5 nm in size and pores up to 100 nm in size combined into clusters (IZ3-6). Also, aerogels have good thermal insulation and hygroscopic properties, they are transparent and through them the state of the wound bed and the features of the wound process are clearly visible. Silicone tubes (through which medical agents are administered) are located in the thickness of the airgel bandage, they have one external exit on the surface of the bandage and pores in its base, from where vitamin B10 gradually enters the wound.

The use of vitamin VTO stimulates metabolic and regenerative processes in the wound, reduces

From the intensity of the inflammatory process. Which, in turn, improves microcirculation in the tissues and shortens the course of the phases of the wound process, prevents over-drying of the wound I7-9|. And the zirconium hemispheres, which are in the airgel bandage, provide constant antiseptic conditions for the wound surfaces.

The method is carried out as follows: wound defects are first treated with dry sterile napkins, maximally adsorbing the wound contents, then the wound is treated with sterile napkins moistened with an aqueous solution of chlorhexidine. After treatment of wound defects, the wound is covered with a sterile napkin and an airgel bandage based on amorphous silicon dioxide with zirconium hemispheres is placed on top of it. A medical substance, namely vitamin B10, is injected directly into the silicone tubes of the airgel bandage. After the introduction of vitamin B1O0 into silicone tubes, one tube remains connected to the syringe, and the second is closed with a plug. An electrode (anode) is placed on top of the plate.

During biophoresis, the anode (positive electrode) is placed over the wound defects, and the cathode (negative electrode) is placed under the affected area (extremity) or on the opposite side of the anode.

The strength of the current acting on wound defects ranges from 5 to 80 μA, the current ionizes vitamin B10, gives ions unidirectional movement into the wound for therapeutic purposes. Without stopping the treatment procedure of biophoresis, after the end of vitamin B10, you can wash the wound surface with an antiseptic solution, injecting it with a syringe through a silicone tube into an airgel bandage, having previously removed the plug. Under the action of galvanic current, part of the drug will fall directly to the wound surface through the pores in the lower surface, and part will leave the cavity of the plate through the outlet tube.

Therefore, the method of biophoresis of wound surfaces with vitamin B1O airgel bandages based on amorphous silicon dioxide enables control over its introduction during the wound galvanization procedure, and, if necessary, allows increasing the dose of the drug directly during the procedure. The method improves the deposition of antiseptic and vitamin VIO in the wound tissues, stimulates microcirculation in the affected tissues, reduces microbial contamination of secretions from the wound, and zirconium hemispheres create constant antiseptic conditions in the wound, which allows to shorten the patient's stay in hospital treatment.

Sources:

1. Lisovska T.V., Husakivska O.V. Biophoresis and biopuncture of biological medicine preparations as an alternative to traditional treatment of chronic endometritis // Ukrainian medical almanac. - 2012. - Volume 15, Issue 6. - P. 107-108. 2. por/limly.taut biz. ru/ik/radez/eIesihorpogeviv.pPiti

Z. Ma, N.5.; Rhemovi, U.N.; UShep, A. 5APegeg, village of M/. Aotryieg vzitshtianyop oi teANApilai zi Ashte-rgorepu geiIayopz5pir oi aegode!5. U. Mop-Aguzi. ZoiiAv 2001, 285, 216-221. 4. Ettepiip, A.; EpAKe, u). Зааііпу ргорепіез апА 5ішАіШіге ой аегоде!5. U. ZoI-Sbe! 5AI.

TeApNpoi. 1997, 8, 781-788. 5. pOrz lim. vrhipdegrgoiezziopa!.Av/ep/hemivm-oi-aegode!-bazeA-taiegia!5-ip-biotelAiAai!- arriiAayopv/11742122 b. per /Luimly.taAri.Aot/oigpai/dei5/5relia! izvyez/ayegodeiv 7. pybrv5 //uzeozuya. tsalirgagu/biopitiApa-go!-myatipim-ia-miatiporoAiBpin-5roishk-432.piti 8. Gubskyi Y.I. Biological chemistry: Textbook. Kyiv-Ternopil: Ukrmedknyga, 2000. - 508 p. 9. per://teAiA!yz.yAo2.peyipAeh/liAii rom|a2gok/0-24

Claims (1)

USEFUL MODEL FORMULA The method of biophoresis of wound surfaces with vitamin B1O0, which includes applying to the wound two electrodes made of dissimilar metals, which are connected by an electrical conductor, the action of which causes a unidirectional circular movement of electrons and a constant galvanic current with a strength of 5-80 μA appears, which differs in that , that an airgel bandage (based on amorphous silicon dioxide) with zirconium hemispheres containing silicone tubes inside, through which vitamin B10 is administered, is applied to the wound surface.