UA134963U - METHOD OF BIOPHORESIS OF WOUND SURFACES BY VITAMIN B5 BY AEROGEL BANDINGS BASED ON AMORPHOUS SILICON DIOXIDE - Google Patents

Abstract

The method of biophoresis of wound surfaces with vitamin B5 involves the application to the wound of two electrodes of dissimilar metals, which are connected by an electrical conductor, which causes a unidirectional circular motion of electrons and there is a constant galvanic current of 5-80 μA. An airgel bandage (based on amorphous silicon dioxide) containing silicone tubes, through which vitamin B5 is injected, is applied to the wound surface.

Description

The useful model belongs to the field of medicine, namely to general surgery, combustiology, traumatology, polytrauma and can be used for adaptation of a skin graft on a wound bed, as well as in the treatment of wound defects with damage to the skin and underlying tissues.

In a well-known method for biophoresis, two electrodes made of dissimilar metals are applied to the affected limb or part of the body, which are connected by an electrical conductor, which causes a unidirectional circular movement of electrons and a constant galvanic current with a strength of 5-80 μA appears. The current ionizes liquid medicinal substances, gives ions unidirectional movement, which is used for treatment (1-21.

The disadvantage of the known method is the impossibility of controlling the dosage of the medicinal substance, namely the preparation of vitamin B5 directly during the process of biophoresis of the wound surface, and the wound dressing does not provide optimal pressure on the wound. When applying a gauze bandage, it is impossible to qualitatively fill the entire wound surface, repeating its relief, and it is also impossible to introduce the therapeutic agent, vitamin B5, into the wound directly, without removing the gauze bandage.

The basis of a useful model is the task of eliminating the indicated shortcomings of the given known method for biophoresis.

The task is solved by the fact that in the method of biophoresis of wound surfaces with vitamin

B5, which includes applying to the wound two electrodes made of dissimilar metals, which are connected by an electrical conductor, which causes a unidirectional circular movement of electrons and a constant galvanic current with a strength of 5-80 μA appears, according to a useful model, an airgel layer is applied to the wound surface glue (based on amorphous silicon dioxide), which contains silicone tubes for the introduction of the therapeutic medium, vitamin B5, both during and after the treatment procedure.

Airgel (based on amorphous silicon dioxide) is a unique material - a gel in which the liquid phase is completely replaced by a gaseous one. This material has a record low density and exhibits a number of unique properties: hardness, transparency, heat resistance, etc. Airgel belongs to the class of mesoporous materials, with the structure of a tree-like network of nanoparticles 2-5 nm in size and pores up to 100 nm in size, combined into clusters I3-6). Also, aerogels have good thermal insulation and hygroscopic properties, they are transparent and the condition is clearly visible through them

From the wound bed and features of the wound process |I5Y. Silicone tubes (through which medical agents are administered) are located in the thickness of the airgel bandage, they have one external outlet on the surface of the bandage and pores in its base, from where B5 gradually enters the wound.

The use of vitamin B5 stimulates metabolic and regenerative processes in the wound, reduces the intensity of the inflammatory process. Which, in turn, improves microcirculation in tissues and shortens the course of phases of the wound process, prevents drying of the wound I7-9|.

The method is carried out as follows: wound defects are first treated with dry sterile napkins, maximally adsorbing the wound contents, then the wound is treated with sterile napkins moistened with an aqueous solution of chlorhexidine. After treatment of wound defects, the wound is covered with a sterile napkin and an airgel bandage based on amorphous silicon dioxide is applied on top of it. A medical substance, namely vitamin B5, is injected directly into the silicone tubes of the airgel bandage. After the introduction of vitamin B5 into silicone tubes, one tube remains connected to the syringe, and the other is closed with a plug.

An electrode (anode) is placed on top of the plate.

During biophoresis, the anode (positive electrode) is placed over the wound defects, and the cathode (negative electrode) is placed under the affected area (extremity) or on the opposite side of the anode.

The strength of the current that acts on wound defects is from 5 to 80 μA, the current ionizes vitamin B5, gives ions unidirectional movement into the wound for treatment. Without stopping the treatment procedure of biophoresis, after the end of vitamin B5, you can wash the wound surface with an antiseptic solution, injecting it with a syringe through a silicone tube into an airgel bandage, having previously removed the stopper. Under the action of galvanic current, part of the drug will fall directly onto the wound surface through the pores in the lower surface, and part will leave the cavity of the plate through the outlet tube.

So, the method of biophoresis of wound surfaces with vitamin B5 airgel bandages based on amorphous silicon dioxide enables control over its introduction during the wound galvanization procedure, and if necessary, allows to increase the dose of the drug directly during the procedure. The method improves the deposition of antiseptic and vitamin B5 in the wound tissue, stimulates microcirculation in the affected tissues, reduces microbial contamination of secretions from the wound, which makes it possible to shorten the patient's stay in hospital treatment. (510)

Sources of information: 1. Lisovska T.V., Husakivska O.V. Biophoresis and biopuncture of biological medicine preparations as an alternative to traditional treatment of chronic endometritis // Ukrainian medical almanac. - 2012. - Volume 15, Issue 6. - P. 107-108. 2. por/lLymly gadiiz.ru/K/radez/eIesitorpogeviv.pPIti.

Z. Ma, N.5.; Rhemovi, U.N.; UShep, A. 5APegeg, village of M/. Aotryieg vzitshianyop oi teANApilai zi Ashte-rgorepu geiIayopz5pir oi aegode!5. U. Mop-Aguzi. ZoiiAv 2001, 285, 216-221. 4. Eyettegpipod, A.; EpAKe, U. Zaaiipu rgorepiezh apA vigyAiShge oi ayegode!v. 9. 5oI-be! 5AI.

TeApNpoi. 1997,8,781-788. 5. perz://Lumly.zrgipdefgotezziopa!.Ае/еп/гемием/-ой-аегоде!-базеА-таиегиа!5-ип-биотеАиАаи!- аррииАайопв/11742122. b. by lime taAri.Aot/oigpai/de!5/5redia! izvtsevz/aegode Iv. 7. pEerv //useozuya. tsalirtatgy/riopitiApa-goI-myatipim-ia-miatiporoAiBpipn-5roiShk-432.piti. 8. Gubsky Yu. I. Biological chemistry: Textbook. Kyiv-Ternopil: Ukrmedknyga, 2000. - 508. 9. per://teAiA!tsv.yAo2.pei.ipAeh//iAi romia2ok/0-24.

Claims (1)

USEFUL MODEL FORMULA The method of biophoresis of wound surfaces with vitamin B5, which includes applying to the wound two electrodes made of dissimilar metals, which are connected by an electrical conductor, which causes a unidirectional circular movement of electrons and a constant galvanic current with a strength of 5- 80 μA, which differs in that an airgel bandage (based on amorphous silicon dioxide) is applied to the wound surface, containing silicone tubes inside, through which vitamin B5 is injected.