UA129123C2 - Рідкий склад на основі нікотину, що містить частково водорозчинний розчинник - Google Patents
Рідкий склад на основі нікотину, що містить частково водорозчинний розчинник Download PDFInfo
- Publication number
- UA129123C2 UA129123C2 UAA202102775A UAA202102775A UA129123C2 UA 129123 C2 UA129123 C2 UA 129123C2 UA A202102775 A UAA202102775 A UA A202102775A UA A202102775 A UAA202102775 A UA A202102775A UA 129123 C2 UA129123 C2 UA 129123C2
- Authority
- UA
- Ukraine
- Prior art keywords
- water
- percent
- weight
- nicotine
- content
- Prior art date
Links
- SNICXCGAKADSCV-JTQLQIEISA-N (-)-Nicotine Chemical compound CN1CCC[C@H]1C1=CC=CN=C1 SNICXCGAKADSCV-JTQLQIEISA-N 0.000 title claims abstract description 514
- 229960002715 nicotine Drugs 0.000 title claims abstract description 509
- SNICXCGAKADSCV-UHFFFAOYSA-N nicotine Natural products CN1CCCC1C1=CC=CN=C1 SNICXCGAKADSCV-UHFFFAOYSA-N 0.000 title claims abstract description 509
- 239000007788 liquid Substances 0.000 title claims abstract description 451
- 239000000203 mixture Substances 0.000 title claims abstract description 448
- 239000003021 water soluble solvent Substances 0.000 title claims description 10
- 238000009472 formulation Methods 0.000 title description 6
- 239000002904 solvent Substances 0.000 claims abstract description 272
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 179
- 239000000443 aerosol Substances 0.000 claims abstract description 115
- 238000005192 partition Methods 0.000 claims abstract description 27
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 claims description 132
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims description 113
- 150000005846 sugar alcohols Polymers 0.000 claims description 66
- 235000011187 glycerol Nutrition 0.000 claims description 56
- 150000007524 organic acids Chemical class 0.000 claims description 17
- 239000007787 solid Substances 0.000 claims description 8
- 239000003995 emulsifying agent Substances 0.000 claims description 7
- URAYPUMNDPQOKB-UHFFFAOYSA-N triacetin Chemical compound CC(=O)OCC(OC(C)=O)COC(C)=O URAYPUMNDPQOKB-UHFFFAOYSA-N 0.000 claims description 6
- PUPZLCDOIYMWBV-UHFFFAOYSA-N (+/-)-1,3-Butanediol Chemical compound CC(O)CCO PUPZLCDOIYMWBV-UHFFFAOYSA-N 0.000 claims description 4
- DOOTYTYQINUNNV-UHFFFAOYSA-N Triethyl citrate Chemical compound CCOC(=O)CC(O)(C(=O)OCC)CC(=O)OCC DOOTYTYQINUNNV-UHFFFAOYSA-N 0.000 claims description 3
- 239000001087 glyceryl triacetate Substances 0.000 claims description 3
- 235000013773 glyceryl triacetate Nutrition 0.000 claims description 3
- 235000005985 organic acids Nutrition 0.000 claims description 3
- 229960002622 triacetin Drugs 0.000 claims description 3
- 239000001069 triethyl citrate Substances 0.000 claims description 3
- VMYFZRTXGLUXMZ-UHFFFAOYSA-N triethyl citrate Natural products CCOC(=O)C(O)(C(=O)OCC)C(=O)OCC VMYFZRTXGLUXMZ-UHFFFAOYSA-N 0.000 claims description 3
- 235000013769 triethyl citrate Nutrition 0.000 claims description 3
- ZIBGPFATKBEMQZ-UHFFFAOYSA-N triethylene glycol Chemical compound OCCOCCOCCO ZIBGPFATKBEMQZ-UHFFFAOYSA-N 0.000 claims description 2
- 239000003799 water insoluble solvent Substances 0.000 claims description 2
- RYYVLZVUVIJVGH-UHFFFAOYSA-N caffeine Chemical compound CN1C(=O)N(C)C(=O)C2=C1N=CN2C RYYVLZVUVIJVGH-UHFFFAOYSA-N 0.000 description 21
- 230000014759 maintenance of location Effects 0.000 description 11
- LPHGQDQBBGAPDZ-UHFFFAOYSA-N Isocaffeine Natural products CN1C(=O)N(C)C(=O)C2=C1N(C)C=N2 LPHGQDQBBGAPDZ-UHFFFAOYSA-N 0.000 description 10
- 229960001948 caffeine Drugs 0.000 description 10
- VJEONQKOZGKCAK-UHFFFAOYSA-N caffeine Natural products CN1C(=O)N(C)C(=O)C2=C1C=CN2C VJEONQKOZGKCAK-UHFFFAOYSA-N 0.000 description 10
- 150000001875 compounds Chemical class 0.000 description 7
- 238000010438 heat treatment Methods 0.000 description 7
- 239000012669 liquid formulation Substances 0.000 description 7
- 238000001179 sorption measurement Methods 0.000 description 7
- 210000004072 lung Anatomy 0.000 description 6
- 210000002345 respiratory system Anatomy 0.000 description 6
- 239000000126 substance Substances 0.000 description 5
- JOOXCMJARBKPKM-UHFFFAOYSA-N 4-oxopentanoic acid Chemical compound CC(=O)CCC(O)=O JOOXCMJARBKPKM-UHFFFAOYSA-N 0.000 description 4
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical group [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 description 4
- 238000003795 desorption Methods 0.000 description 4
- 239000012530 fluid Substances 0.000 description 4
- JVTAAEKCZFNVCJ-UHFFFAOYSA-N lactic acid Chemical compound CC(O)C(O)=O JVTAAEKCZFNVCJ-UHFFFAOYSA-N 0.000 description 4
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 description 3
- 229910052799 carbon Inorganic materials 0.000 description 3
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 description 3
- 230000000087 stabilizing effect Effects 0.000 description 3
- KBPLFHHGFOOTCA-UHFFFAOYSA-N 1-Octanol Chemical compound CCCCCCCCO KBPLFHHGFOOTCA-UHFFFAOYSA-N 0.000 description 2
- OFOBLEOULBTSOW-UHFFFAOYSA-N Malonic acid Chemical compound OC(=O)CC(O)=O OFOBLEOULBTSOW-UHFFFAOYSA-N 0.000 description 2
- LCTONWCANYUPML-UHFFFAOYSA-N Pyruvic acid Chemical compound CC(=O)C(O)=O LCTONWCANYUPML-UHFFFAOYSA-N 0.000 description 2
- 239000002585 base Substances 0.000 description 2
- 150000001735 carboxylic acids Chemical class 0.000 description 2
- 239000003795 chemical substances by application Substances 0.000 description 2
- 235000019504 cigarettes Nutrition 0.000 description 2
- 230000008021 deposition Effects 0.000 description 2
- 239000012153 distilled water Substances 0.000 description 2
- 239000003571 electronic cigarette Substances 0.000 description 2
- 239000000796 flavoring agent Substances 0.000 description 2
- 235000019634 flavors Nutrition 0.000 description 2
- 239000012456 homogeneous solution Substances 0.000 description 2
- 230000006698 induction Effects 0.000 description 2
- 239000004310 lactic acid Substances 0.000 description 2
- 235000014655 lactic acid Nutrition 0.000 description 2
- 229940040102 levulinic acid Drugs 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 239000002245 particle Substances 0.000 description 2
- 239000000779 smoke Substances 0.000 description 2
- NOOLISFMXDJSKH-UTLUCORTSA-N (+)-Neomenthol Chemical compound CC(C)[C@@H]1CC[C@@H](C)C[C@@H]1O NOOLISFMXDJSKH-UTLUCORTSA-N 0.000 description 1
- WRIDQFICGBMAFQ-UHFFFAOYSA-N (E)-8-Octadecenoic acid Natural products CCCCCCCCCC=CCCCCCCC(O)=O WRIDQFICGBMAFQ-UHFFFAOYSA-N 0.000 description 1
- BJEPYKJPYRNKOW-REOHCLBHSA-N (S)-malic acid Chemical compound OC(=O)[C@@H](O)CC(O)=O BJEPYKJPYRNKOW-REOHCLBHSA-N 0.000 description 1
- VBICKXHEKHSIBG-UHFFFAOYSA-N 1-monostearoylglycerol Chemical compound CCCCCCCCCCCCCCCCCC(=O)OCC(O)CO VBICKXHEKHSIBG-UHFFFAOYSA-N 0.000 description 1
- LQJBNNIYVWPHFW-UHFFFAOYSA-N 20:1omega9c fatty acid Natural products CCCCCCCCCCC=CCCCCCCCC(O)=O LQJBNNIYVWPHFW-UHFFFAOYSA-N 0.000 description 1
- QSBYPNXLFMSGKH-UHFFFAOYSA-N 9-Heptadecensaeure Natural products CCCCCCCC=CCCCCCCCC(O)=O QSBYPNXLFMSGKH-UHFFFAOYSA-N 0.000 description 1
- 102000011632 Caseins Human genes 0.000 description 1
- 108010076119 Caseins Proteins 0.000 description 1
- NOOLISFMXDJSKH-UHFFFAOYSA-N DL-menthol Natural products CC(C)C1CCC(C)CC1O NOOLISFMXDJSKH-UHFFFAOYSA-N 0.000 description 1
- 239000005642 Oleic acid Substances 0.000 description 1
- ZQPPMHVWECSIRJ-UHFFFAOYSA-N Oleic acid Natural products CCCCCCCCC=CCCCCCCCC(O)=O ZQPPMHVWECSIRJ-UHFFFAOYSA-N 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- BJEPYKJPYRNKOW-UHFFFAOYSA-N alpha-hydroxysuccinic acid Natural products OC(=O)C(O)CC(O)=O BJEPYKJPYRNKOW-UHFFFAOYSA-N 0.000 description 1
- 230000002051 biphasic effect Effects 0.000 description 1
- 235000019658 bitter taste Nutrition 0.000 description 1
- -1 caffeine cations Chemical class 0.000 description 1
- 239000011248 coating agent Substances 0.000 description 1
- 238000000576 coating method Methods 0.000 description 1
- 238000002485 combustion reaction Methods 0.000 description 1
- 125000003074 decanoyl group Chemical group [H]C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(*)=O 0.000 description 1
- 235000019329 dioctyl sodium sulphosuccinate Nutrition 0.000 description 1
- 229960000878 docusate sodium Drugs 0.000 description 1
- 238000005538 encapsulation Methods 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 230000008020 evaporation Effects 0.000 description 1
- 238000001704 evaporation Methods 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 239000012458 free base Substances 0.000 description 1
- JEGUKCSWCFPDGT-UHFFFAOYSA-N h2o hydrate Chemical compound O.O JEGUKCSWCFPDGT-UHFFFAOYSA-N 0.000 description 1
- 230000007794 irritation Effects 0.000 description 1
- QXJSBBXBKPUZAA-UHFFFAOYSA-N isooleic acid Natural products CCCCCCCC=CCCCCCCCCC(O)=O QXJSBBXBKPUZAA-UHFFFAOYSA-N 0.000 description 1
- 239000001630 malic acid Substances 0.000 description 1
- 235000011090 malic acid Nutrition 0.000 description 1
- 229940041616 menthol Drugs 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- ZQPPMHVWECSIRJ-KTKRTIGZSA-N oleic acid Chemical compound CCCCCCCC\C=C/CCCCCCCC(O)=O ZQPPMHVWECSIRJ-KTKRTIGZSA-N 0.000 description 1
- 235000019629 palatability Nutrition 0.000 description 1
- 239000000244 polyoxyethylene sorbitan monooleate Substances 0.000 description 1
- 235000010482 polyoxyethylene sorbitan monooleate Nutrition 0.000 description 1
- 229920000053 polysorbate 80 Polymers 0.000 description 1
- 229940068968 polysorbate 80 Drugs 0.000 description 1
- 230000002265 prevention Effects 0.000 description 1
- 210000003456 pulmonary alveoli Anatomy 0.000 description 1
- 229940107700 pyruvic acid Drugs 0.000 description 1
- 229940080237 sodium caseinate Drugs 0.000 description 1
- APSBXTVYXVQYAB-UHFFFAOYSA-M sodium docusate Chemical compound [Na+].CCCCC(CC)COC(=O)CC(S([O-])(=O)=O)C(=O)OCC(CC)CCCC APSBXTVYXVQYAB-UHFFFAOYSA-M 0.000 description 1
- BTURAGWYSMTVOW-UHFFFAOYSA-M sodium dodecanoate Chemical compound [Na+].CCCCCCCCCCCC([O-])=O BTURAGWYSMTVOW-UHFFFAOYSA-M 0.000 description 1
- 239000007921 spray Substances 0.000 description 1
- 238000012144 step-by-step procedure Methods 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
- 238000002604 ultrasonography Methods 0.000 description 1
- 235000013311 vegetables Nutrition 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
- A24B—MANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
- A24B15/00—Chemical features or treatment of tobacco; Tobacco substitutes, e.g. in liquid form
- A24B15/10—Chemical features of tobacco products or tobacco substitutes
- A24B15/16—Chemical features of tobacco products or tobacco substitutes of tobacco substitutes
- A24B15/167—Chemical features of tobacco products or tobacco substitutes of tobacco substitutes in liquid or vaporisable form, e.g. liquid compositions for electronic cigarettes
-
- A—HUMAN NECESSITIES
- A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
- A24B—MANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
- A24B15/00—Chemical features or treatment of tobacco; Tobacco substitutes, e.g. in liquid form
- A24B15/18—Treatment of tobacco products or tobacco substitutes
- A24B15/24—Treatment of tobacco products or tobacco substitutes by extraction; Tobacco extracts
- A24B15/241—Extraction of specific substances
- A24B15/243—Nicotine
-
- A—HUMAN NECESSITIES
- A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
- A24B—MANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
- A24B15/00—Chemical features or treatment of tobacco; Tobacco substitutes, e.g. in liquid form
- A24B15/18—Treatment of tobacco products or tobacco substitutes
- A24B15/28—Treatment of tobacco products or tobacco substitutes by chemical substances
-
- A—HUMAN NECESSITIES
- A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
- A24B—MANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
- A24B15/00—Chemical features or treatment of tobacco; Tobacco substitutes, e.g. in liquid form
- A24B15/18—Treatment of tobacco products or tobacco substitutes
- A24B15/28—Treatment of tobacco products or tobacco substitutes by chemical substances
- A24B15/30—Treatment of tobacco products or tobacco substitutes by chemical substances by organic substances
-
- A—HUMAN NECESSITIES
- A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
- A24B—MANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
- A24B15/00—Chemical features or treatment of tobacco; Tobacco substitutes, e.g. in liquid form
- A24B15/18—Treatment of tobacco products or tobacco substitutes
- A24B15/28—Treatment of tobacco products or tobacco substitutes by chemical substances
- A24B15/30—Treatment of tobacco products or tobacco substitutes by chemical substances by organic substances
- A24B15/32—Treatment of tobacco products or tobacco substitutes by chemical substances by organic substances by acyclic compounds
-
- A—HUMAN NECESSITIES
- A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
- A24F—SMOKERS' REQUISITES; MATCH BOXES; SIMULATED SMOKING DEVICES
- A24F40/00—Electrically operated smoking devices; Component parts thereof; Manufacture thereof; Maintenance or testing thereof; Charging means specially adapted therefor
- A24F40/05—Devices without heating means
-
- A—HUMAN NECESSITIES
- A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
- A24F—SMOKERS' REQUISITES; MATCH BOXES; SIMULATED SMOKING DEVICES
- A24F40/00—Electrically operated smoking devices; Component parts thereof; Manufacture thereof; Maintenance or testing thereof; Charging means specially adapted therefor
- A24F40/10—Devices using liquid inhalable precursors
-
- A—HUMAN NECESSITIES
- A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
- A24F—SMOKERS' REQUISITES; MATCH BOXES; SIMULATED SMOKING DEVICES
- A24F40/00—Electrically operated smoking devices; Component parts thereof; Manufacture thereof; Maintenance or testing thereof; Charging means specially adapted therefor
- A24F40/40—Constructional details, e.g. connection of cartridges and battery parts
- A24F40/42—Cartridges or containers for inhalable precursors
-
- A—HUMAN NECESSITIES
- A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
- A24F—SMOKERS' REQUISITES; MATCH BOXES; SIMULATED SMOKING DEVICES
- A24F40/00—Electrically operated smoking devices; Component parts thereof; Manufacture thereof; Maintenance or testing thereof; Charging means specially adapted therefor
- A24F40/40—Constructional details, e.g. connection of cartridges and battery parts
- A24F40/46—Shape or structure of electric heating means
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/465—Nicotine; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/0078—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/12—Aerosols; Foams
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Health & Medical Sciences (AREA)
- Toxicology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Dispersion Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Otolaryngology (AREA)
- Pulmonology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Manufacture Of Tobacco Products (AREA)
Applications Claiming Priority (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP18215983 | 2018-12-31 | ||
| EP18215969 | 2018-12-31 | ||
| EP18215976 | 2018-12-31 | ||
| EP18215966 | 2018-12-31 | ||
| EP18215964 | 2018-12-31 | ||
| PCT/EP2019/087196 WO2020141178A1 (en) | 2018-12-31 | 2019-12-31 | Liquid nicotine formulation comprising partially water-soluble solvent |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| UA129123C2 true UA129123C2 (uk) | 2025-01-22 |
Family
ID=69104449
Family Applications (5)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| UAA202102775A UA129123C2 (uk) | 2018-12-31 | 2019-12-31 | Рідкий склад на основі нікотину, що містить частково водорозчинний розчинник |
| UAA202101799A UA129122C2 (uk) | 2018-12-31 | 2019-12-31 | Рідкий склад нікотину |
| UAA202101830A UA129018C2 (uk) | 2018-12-31 | 2019-12-31 | Рідкий склад нікотину |
| UAA202101822A UA128585C2 (uk) | 2018-12-31 | 2019-12-31 | Рідкий склад на основі нікотину, що містить розчинники, які не змішуються з водою |
| UAA202102774A UA129019C2 (uk) | 2018-12-31 | 2019-12-31 | Рідкий склад на основі нікотину з низькою в'язкістю |
Family Applications After (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| UAA202101799A UA129122C2 (uk) | 2018-12-31 | 2019-12-31 | Рідкий склад нікотину |
| UAA202101830A UA129018C2 (uk) | 2018-12-31 | 2019-12-31 | Рідкий склад нікотину |
| UAA202101822A UA128585C2 (uk) | 2018-12-31 | 2019-12-31 | Рідкий склад на основі нікотину, що містить розчинники, які не змішуються з водою |
| UAA202102774A UA129019C2 (uk) | 2018-12-31 | 2019-12-31 | Рідкий склад на основі нікотину з низькою в'язкістю |
Country Status (11)
| Country | Link |
|---|---|
| US (5) | US20220053817A1 (enExample) |
| EP (5) | EP3905898B1 (enExample) |
| JP (6) | JP2022516896A (enExample) |
| KR (5) | KR20210108390A (enExample) |
| CN (5) | CN113163846B (enExample) |
| BR (4) | BR112021010284A2 (enExample) |
| ES (2) | ES2980261T3 (enExample) |
| MX (5) | MX2021007623A (enExample) |
| PL (2) | PL3905898T3 (enExample) |
| UA (5) | UA129123C2 (enExample) |
| WO (5) | WO2020141180A1 (enExample) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP7013754B2 (ja) * | 2017-09-15 | 2022-02-01 | 株式会社三洋物産 | 遊技機 |
| BR112021010229A2 (pt) | 2018-12-28 | 2021-08-24 | Philip Morris Products S.A. | Formulação de nicotina líquida compreendendo sal de metal de baixa massa molar |
| MX2021007623A (es) * | 2018-12-31 | 2021-08-11 | Philip Morris Products Sa | Formulacion liquida de nicotina que comprende solventes inmiscibles en agua. |
| EP4056055A1 (en) * | 2021-03-09 | 2022-09-14 | Avogen Tech SA | Device for volatilisation of an aqueous solution and method thereof |
| GB202110541D0 (en) * | 2021-07-22 | 2021-09-08 | Nicoventures Trading Ltd | Delivery system |
| KR102416605B1 (ko) | 2021-08-17 | 2022-07-05 | 한국과학기술원 | 비트라인 멀티 레벨 전압 센싱 회로 |
| IT202100027086A1 (it) * | 2021-10-21 | 2023-04-21 | Alberto Patarchi | Erogatore portatile per il trattamento o la prevenzione di un’infezione o di una patologia causata da un virus |
| CN113912585B (zh) * | 2021-11-09 | 2023-02-24 | 深圳萨特瓦生物科技有限公司 | 复合尼古丁盐及其制备方法与应用、电子烟油及电子烟 |
| CN116235996A (zh) * | 2021-12-07 | 2023-06-09 | 深圳雾芯科技有限公司 | 电子烟液及包含其的雾化装置 |
| KR20240012197A (ko) * | 2022-07-20 | 2024-01-29 | 주식회사 케이티앤지 | 표면파 아토마이저에 사용하기 위한 액상형 흡입제형, 이를 포함하는 카트리지 및 에어로졸 생성장치 |
| KR102872477B1 (ko) * | 2022-08-10 | 2025-10-20 | 주식회사 케이티앤지 | 니코틴 흡입성 조성물 및 이를 포함하는 에어로졸 발생 장치 및 시스템 |
| KR102885439B1 (ko) * | 2022-10-07 | 2025-11-17 | 주식회사 케이티앤지 | 에어로졸 흡입기용 액상 조성물 |
| CN117204598A (zh) * | 2023-07-05 | 2023-12-12 | 深圳梵活生命科学股份有限公司 | 一种应用于雾化器可缓解烟瘾的雾化液 |
| WO2025230261A1 (ko) * | 2024-04-30 | 2025-11-06 | 주식회사 케이티앤지 | 에어로졸 생성물품용 시트 및 이를 포함하는 에어로졸 생성물품 |
Family Cites Families (60)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0845220B1 (en) * | 1996-06-17 | 2003-09-03 | Japan Tobacco Inc. | Flavor producing article |
| WO2006004646A1 (en) * | 2004-06-28 | 2006-01-12 | Nektar Therapeutics | Aerosol formulation comprising nicotine salt |
| JP2006109784A (ja) * | 2004-10-15 | 2006-04-27 | Mitsubishi Gas Chem Co Inc | パクリタキセルの製造方法 |
| US20070060639A1 (en) | 2005-09-09 | 2007-03-15 | University Of Kentucky | Compositions and methods for intranasal delivery of tricyclic cannabinoids |
| WO2007078273A1 (en) * | 2005-12-22 | 2007-07-12 | Augite Incorporation | No-tar electronic smoking utensils |
| JP2010535774A (ja) | 2007-08-06 | 2010-11-25 | インシス セラピューティクス インコーポレイテッド | 経口カンナビノイド液体製剤および治療方法 |
| US9314524B2 (en) * | 2007-12-31 | 2016-04-19 | Calla Therapeutics Llc | Topical formulations of Flucytosine |
| US20120325228A1 (en) * | 2011-06-23 | 2012-12-27 | Williams Jonnie R | Alkaloid composition for e-cigarette |
| DE102011114094A1 (de) | 2011-09-21 | 2013-03-21 | F. Holzer Gmbh | Stimulierendes und belebendes Nasenspray und Nasentropfen |
| SMT201900220T1 (it) * | 2012-03-27 | 2019-07-11 | Nicoccino Ab | Formulazione di nicotina |
| DE102012104033B9 (de) | 2012-05-08 | 2025-02-06 | Tdk Electronics Ag | Keramischer Vielschichtkondensator |
| US10799548B2 (en) * | 2013-03-15 | 2020-10-13 | Altria Client Services Llc | Modifying taste and sensory irritation of smokeless tobacco and non-tobacco products |
| KR102490695B1 (ko) | 2013-05-06 | 2023-01-19 | 쥴 랩스, 인크. | 에어로졸 장치를 위한 니코틴 염 제제 및 그 방법 |
| WO2015006465A1 (en) | 2013-07-10 | 2015-01-15 | Ahkeo Ventures LLC | Inhalable compositions comprising caffeine, methods of use and an apparatus for using the same |
| WO2015009862A2 (en) | 2013-07-19 | 2015-01-22 | Altria Client Services Inc. | Liquid aerosol formulation of an electronic smoking article |
| US10265292B2 (en) * | 2013-09-18 | 2019-04-23 | The Werc Shop, LLC | Terpene-based compositions, processes methodologies |
| CN105491899B (zh) | 2013-09-19 | 2018-10-30 | 菲利普莫里斯生产公司 | 用于生成烟碱盐颗粒的气雾生成系统 |
| WO2015042589A1 (en) * | 2013-09-23 | 2015-03-26 | Verso PV, LLC | Personal vaporizer liquid for emulsifying oil-soluble compounds and resins |
| US9333229B2 (en) | 2013-10-16 | 2016-05-10 | William Bjorncrantz | Winterized crude cannabis extracts and methods of preparation and use |
| US10292424B2 (en) * | 2013-10-31 | 2019-05-21 | Rai Strategic Holdings, Inc. | Aerosol delivery device including a pressure-based aerosol delivery mechanism |
| CN103622161A (zh) | 2013-11-28 | 2014-03-12 | 刘秋明 | 一种电子烟烟液溶剂及电子烟烟液 |
| CN103598672A (zh) * | 2013-11-28 | 2014-02-26 | 刘秋明 | 一种电子烟烟液溶剂及电子烟烟液 |
| EP4552512A3 (en) * | 2013-12-05 | 2025-07-02 | Juul Labs, Inc. | Nicotine liquid formulations for aerosol devices and methods thereof |
| WO2015117243A1 (en) | 2014-02-07 | 2015-08-13 | Bellerose Samuel | Liquid formulation for e-cigarettes |
| US9375033B2 (en) | 2014-02-14 | 2016-06-28 | R.J. Reynolds Tobacco Company | Tobacco-containing gel composition |
| GB201407426D0 (en) * | 2014-04-28 | 2014-06-11 | Batmark Ltd | Aerosol forming component |
| WO2015167629A1 (en) * | 2014-04-30 | 2015-11-05 | Altria Client Services Inc. | Liquid aerosol formulation of an electronic smoking article |
| EP3145492A1 (en) * | 2014-05-21 | 2017-03-29 | McNeil AB | A liquid formulation comprising nicotine for aerosol administration |
| EP3166428B1 (en) * | 2014-07-11 | 2021-09-01 | Philip Morris Products S.A. | Aerosol-generating system with improved air flow control |
| JP6660370B2 (ja) * | 2014-07-11 | 2020-03-11 | フィリップ・モーリス・プロダクツ・ソシエテ・アノニム | 液体ニコチン供与源を備えるエアロゾル形成カートリッジ |
| CN104256885B (zh) * | 2014-08-05 | 2015-12-30 | 云南中烟工业有限责任公司 | 一种电子烟烟液溶剂 |
| GB2535427A (en) | 2014-11-07 | 2016-08-24 | Nicoventures Holdings Ltd | Solution |
| GB2532062A (en) * | 2014-11-07 | 2016-05-11 | Nicoventures Holdings Ltd | Container |
| US10470090B2 (en) | 2014-11-14 | 2019-11-05 | Qualcomm Incorporated | Data compression techniques for handover and radio link failure recovery |
| CN104473323A (zh) * | 2014-12-03 | 2015-04-01 | 河南中烟工业有限责任公司 | 一种电子烟雾化剂 |
| CN104585880B (zh) * | 2015-01-20 | 2018-06-08 | 湖北中烟工业有限责任公司 | 一种用于烟用滴丸的薄荷香精溶剂 |
| WO2016133890A1 (en) * | 2015-02-19 | 2016-08-25 | Srq Patent Holdings, Llc | Compositions for e-cigarettes |
| CN104939305B (zh) * | 2015-05-20 | 2016-04-20 | 湖南中烟工业有限责任公司 | 一种烟草提取物及电子烟液 |
| US20160345621A1 (en) * | 2015-06-01 | 2016-12-01 | San Li | Pre-vapor formulation of an electronic vaping device and/or methods of manufacturing the same |
| GB2542389A (en) | 2015-09-17 | 2017-03-22 | Kind Consumer Ltd | Simulated cigarette |
| US10327472B2 (en) * | 2015-09-25 | 2019-06-25 | Altria Client Services Llc | Pre-vaporization formulation for controlling acidity in an e-vaping device |
| CN106562469A (zh) * | 2015-10-07 | 2017-04-19 | 惠州市吉瑞科技有限公司 | 电子烟烟液 |
| KR102661607B1 (ko) | 2015-11-02 | 2024-04-30 | 필립모리스 프로덕츠 에스.에이. | 진동 부재를 포함하는 에어로졸 발생 시스템 |
| GB2544468A (en) | 2015-11-12 | 2017-05-24 | Jaytee Biosciences Ltd | Liquid formulation |
| WO2017132308A1 (en) * | 2016-01-29 | 2017-08-03 | The Procter & Gamble Company | Composition for enhancing hair fiber properties |
| US20170325494A1 (en) | 2016-05-16 | 2017-11-16 | Lunatech, Llc | Liquid composition containing nicotine from non-tobacco source for use with electronic vaporizing devices |
| CA3016255A1 (en) * | 2016-05-27 | 2017-11-30 | Philip Morris Products S.A. | Aerosol-generating article having a liquid indicator |
| US20170348494A1 (en) | 2016-06-06 | 2017-12-07 | Nicholas A. Havercroft | Pulmonary device, method and system for delivering a pharmaceutical product to an individual |
| US20170367386A1 (en) | 2016-06-24 | 2017-12-28 | Allied Concessions Group, Inc. | Terpene flavoring compositions |
| CN106036990B (zh) * | 2016-08-03 | 2018-10-12 | 华健 | 一种复合醇电子烟雾化液 |
| WO2018031600A1 (en) * | 2016-08-08 | 2018-02-15 | Juul Labs, Inc. | Nicotine oxalic acid formulations |
| US20180084823A1 (en) | 2016-09-27 | 2018-03-29 | BOND STREET MANUFACTURING LLC (a Florida LLC) | Vaporizable Tobacco Wax Compositions and Container thereof |
| US20180103680A1 (en) | 2016-10-18 | 2018-04-19 | Altria Client Services Llc | Methods and systems for improving stability of the pre-vapor formulation of an e-vaping device |
| IL270625B (en) * | 2017-06-08 | 2022-09-01 | Philip Morris Products Sa | Cartridge having a susceptor material |
| EP3793745B1 (en) | 2018-05-16 | 2022-07-06 | Philip Morris Products S.A. | Atomizer and a mesh therefor |
| CN112040798B (zh) | 2018-05-16 | 2024-04-05 | 菲利普莫里斯生产公司 | 具有振动室的雾化器组件 |
| EP3574902A1 (en) * | 2018-06-01 | 2019-12-04 | Yatzz Limited | Nicotine formulation and mode of delivery |
| GB201818711D0 (en) * | 2018-11-16 | 2019-01-02 | Nicoventures Trading Ltd | Method |
| MX2021007623A (es) * | 2018-12-31 | 2021-08-11 | Philip Morris Products Sa | Formulacion liquida de nicotina que comprende solventes inmiscibles en agua. |
| WO2020248071A1 (en) * | 2019-06-12 | 2020-12-17 | Lunaverse Inc. | Method and system for trichome isolation |
-
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