UA106945C2 - Спосіб отримання 4-аміно-3-хлор-5-фтор-6-(заміщених)піколінатів - Google Patents

Спосіб отримання 4-аміно-3-хлор-5-фтор-6-(заміщених)піколінатів

Info

Publication number
UA106945C2
UA106945C2 UAA201310403A UAA201310403A UA106945C2 UA 106945 C2 UA106945 C2 UA 106945C2 UA A201310403 A UAA201310403 A UA A201310403A UA A201310403 A UAA201310403 A UA A201310403A UA 106945 C2 UA106945 C2 UA 106945C2
Authority
UA
Ukraine
Prior art keywords
libreofficeof
preparation
exchange
tetrachloropicolinoni
aminalion
Prior art date
Application number
UAA201310403A
Other languages
English (en)
Russian (ru)
Inventor
Кім Е. Арндт
Джеймс М. Ренга
Юаньмін Чжу
Грегорі Т. Уайтекер
Крістіан Т. Лоу
Original Assignee
ДАУ АГРОСАЙЄНСІЗ ЕлЕлСі
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ДАУ АГРОСАЙЄНСІЗ ЕлЕлСі filed Critical ДАУ АГРОСАЙЄНСІЗ ЕлЕлСі
Publication of UA106945C2 publication Critical patent/UA106945C2/uk

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/84—Nitriles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72—Nitrogen atoms
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/34—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom
    • A01N43/40—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom six-membered rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/79—Acids; Esters
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/79—Acids; Esters
    • C07D213/803—Processes of preparation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/81—Amides; Imides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Pest Control & Pesticides (AREA)
  • Plant Pathology (AREA)
  • Agronomy & Crop Science (AREA)
  • Engineering & Computer Science (AREA)
  • Dentistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Pyridine Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

4-Аміно-3-хлор-5-фтор-6-(заміщені)піколінати зручно отримувати з 3,4,5,6-тетрахлорпіколінонітрилу, використовуючи ряд стадій, що включають фторидне заміщення, амінування, галогенідне заміщення і гідроліз, етерифікацію і каталізоване перехідними металами поєднання.
UAA201310403A 2011-01-25 2012-01-24 Спосіб отримання 4-аміно-3-хлор-5-фтор-6-(заміщених)піколінатів UA106945C2 (uk)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201161435966P 2011-01-25 2011-01-25
PCT/US2012/022285 WO2012103041A2 (en) 2011-01-25 2012-01-24 Process for the preparation of 4-amino-3-chloro-5-fluoro-6-(substituted) picolinates

Publications (1)

Publication Number Publication Date
UA106945C2 true UA106945C2 (uk) 2014-10-27

Family

ID=46544648

Family Applications (1)

Application Number Title Priority Date Filing Date
UAA201310403A UA106945C2 (uk) 2011-01-25 2012-01-24 Спосіб отримання 4-аміно-3-хлор-5-фтор-6-(заміщених)піколінатів

Country Status (20)

Country Link
US (3) US20120190857A1 (uk)
EP (1) EP2668163B1 (uk)
JP (1) JP5739018B2 (uk)
KR (1) KR101537879B1 (uk)
CN (2) CN103874685B (uk)
AR (1) AR085022A1 (uk)
AU (1) AU2012209277B2 (uk)
BR (2) BR102012001636A2 (uk)
CA (1) CA2825475C (uk)
CO (1) CO6731125A2 (uk)
HK (2) HK1199245A1 (uk)
IL (1) IL227646A (uk)
MX (1) MX342328B (uk)
PL (1) PL2668163T3 (uk)
RU (1) RU2545021C1 (uk)
SG (1) SG192093A1 (uk)
TW (1) TWI592401B (uk)
UA (1) UA106945C2 (uk)
WO (1) WO2012103041A2 (uk)
ZA (1) ZA201305577B (uk)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI592401B (zh) 2011-01-25 2017-07-21 陶氏農業科學公司 用於製備４－胺基－３－氯－５－氟－６－（經取代的）吡啶甲酸酯的方法（一）
MY184855A (en) 2013-03-15 2021-04-27 Dow Agrosciences Llc 4-amino-6-(heterocyclic)picolinates and 6-amino-2-(heterocyclic)pyrimidine-4-carboxylates and their use as herbicides
US9113629B2 (en) 2013-03-15 2015-08-25 Dow Agrosciences Llc 4-amino-6-(4-substituted-phenyl)-picolinates and 6-amino-2-(4-substituted-phenyl)-pyrimidine-4-carboxylates and their use as herbicides
US9637505B2 (en) 2013-03-15 2017-05-02 Dow Agrosciences Llc 4-amino-6-(heterocyclic)picolinates and 6-amino-2-(heterocyclic)pyrimidine-4-carboxylates and their use as herbicides
EP2967057B1 (en) 2013-03-15 2018-11-21 Dow AgroSciences LLC Novel 4-aminopyridine and 6-aminopyrimidine carboxylates as herbicides
TW201609652A (zh) 2013-11-12 2016-03-16 陶氏農業科學公司 用於氟化化合物之過程（三）
TW201609651A (zh) 2013-11-12 2016-03-16 陶氏農業科學公司 用於氟化化合物之過程（一）
TW201524956A (zh) * 2013-11-12 2015-07-01 Dow Agrosciences Llc 用於氟化化合物之過程（二）
TWI726900B (zh) 2015-08-04 2021-05-11 美商陶氏農業科學公司 用於氟化化合物之過程
MX2018014174A (es) * 2016-05-19 2019-03-14 Dow Agrosciences Llc Sintesis de 6-aril-4-aminopicolinatos y 2-aril-6-aminopirimidin-4- carboxilatos mediante acoplamiento suzuki directo.
CN107954925A (zh) * 2016-10-18 2018-04-24 内蒙古佳瑞米精细化工有限公司 一种2,3-二氯-5-三氟甲基吡啶前杂的去除方法
WO2020061146A1 (en) 2018-09-19 2020-03-26 Dow Agrosciences Llc Preparation of halogen analogs of picloram
EP4121416A1 (en) * 2020-03-18 2023-01-25 Corteva Agriscience LLC Improved synthesis of 6-aryl-4-aminopicolinates
BR112022018508A2 (pt) 2020-03-18 2022-10-25 Corteva Agriscience Llc Síntese melhorada de 4-amino-6-(heterocíclico)picolinatos

Family Cites Families (16)

* Cited by examiner, † Cited by third party
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US3285925A (en) * 1962-03-06 1966-11-15 Dow Chemical Co Amino-trichloropicolinic acid compounds
US3803159A (en) * 1967-12-26 1974-04-09 Dow Chemical Co Fluorine containing cyanopyridines
US3629424A (en) * 1967-12-26 1971-12-21 Dow Chemical Co Cyanofluoropyridines and fungicidal compositions and methods for using the same
US4336384A (en) * 1981-04-23 1982-06-22 The Dow Chemical Company Preparation of 4-amino-3,5,6-trichloropicolinic acid
US5710106A (en) * 1996-02-22 1998-01-20 American Cyanamid Company Substituted pyridine herbicidal agents
FR2803592A1 (fr) * 2000-01-06 2001-07-13 Aventis Cropscience Sa Nouveaux derives de l'acide 3-hydroxypicolinique, leur procede de preparation et compositions fongicides les contenant.
ES2368326T3 (es) * 2000-01-14 2011-11-16 Dow Agrosciences Llc 4-aminopicolinatos y su uso como herbicidas.
US6297197B1 (en) 2000-01-14 2001-10-02 Dow Agrosciences Llc 4-aminopicolinates and their use as herbicides
AR037228A1 (es) 2001-07-30 2004-11-03 Dow Agrosciences Llc Compuestos del acido 6-(aril o heteroaril)-4-aminopicolinico, composicion herbicida que los comprende y metodo para controlar vegetacion no deseada
UA82358C2 (uk) * 2003-04-02 2008-04-10 Дау Агросайенсиз Ллс 6-алкіл або алкеніл-4-амінопіколінати гербіцидна композиція, спосіб боротьби з небажаною рослинністю
BR122015016965B8 (pt) * 2006-01-13 2022-06-28 Dow Agrosciences Llc 6-(aril polissubstituído)-4-aminopicolinatos, composição herbicida, e método para controle de vegetação indesejável
PL2193120T3 (pl) * 2007-10-02 2017-01-31 Dow Agrosciences Llc Kwasy 2'podstowione-6-amino-5-alkilo-, alkenylo- lub alkinylo-4-pirymidynokarboksylowe i kwasy 6-podstawione-4-amino-3-alkilo-, alkenylo- lub alkinylopikolinowe oraz ich zastosowanie jako herbicydy
US8252938B2 (en) * 2009-06-08 2012-08-28 Dow Agrosciences, Llc. Process for the preparation of 6-(aryl)-4-aminopicolinates
GB0910766D0 (en) * 2009-06-22 2009-08-05 Syngenta Ltd Chemical compounds
GB201008290D0 (en) * 2010-05-18 2010-06-30 Syngenta Ltd Chemical compounds
TWI592401B (zh) 2011-01-25 2017-07-21 陶氏農業科學公司 用於製備４－胺基－３－氯－５－氟－６－（經取代的）吡啶甲酸酯的方法（一）

Also Published As

Publication number Publication date
US9067890B2 (en) 2015-06-30
SG192093A1 (en) 2013-08-30
IL227646A0 (en) 2013-09-30
KR101537879B1 (ko) 2015-07-17
AU2012209277B2 (en) 2015-09-17
IL227646A (en) 2016-10-31
CA2825475C (en) 2017-08-22
CA2825475A1 (en) 2012-08-02
CN104788368A (zh) 2015-07-22
KR20130121950A (ko) 2013-11-06
WO2012103041A3 (en) 2014-05-01
CN104788368B (zh) 2017-09-26
EP2668163A4 (en) 2015-03-11
US20150274669A1 (en) 2015-10-01
RU2545021C1 (ru) 2015-03-27
WO2012103041A2 (en) 2012-08-02
CO6731125A2 (es) 2013-08-15
US9452984B2 (en) 2016-09-27
RU2013139300A (ru) 2015-04-10
TW201309649A (zh) 2013-03-01
PL2668163T3 (pl) 2017-10-31
EP2668163A2 (en) 2013-12-04
MX2013008603A (es) 2013-08-12
JP2014515725A (ja) 2014-07-03
CN103874685A (zh) 2014-06-18
BR112013019025A2 (pt) 2016-07-12
EP2668163B1 (en) 2017-05-10
CN103874685B (zh) 2016-02-03
BR102012001636A2 (pt) 2015-07-28
US20120190857A1 (en) 2012-07-26
US20140142317A1 (en) 2014-05-22
HK1213875A1 (zh) 2016-07-15
AR085022A1 (es) 2013-08-07
JP5739018B2 (ja) 2015-06-24
HK1199245A1 (en) 2015-06-26
TWI592401B (zh) 2017-07-21
ZA201305577B (en) 2014-09-25
MX342328B (es) 2016-09-22

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