UA105375C2 - Спосіб виготовлення вагінального супозиторія - Google Patents
Спосіб виготовлення вагінального супозиторіяInfo
- Publication number
- UA105375C2 UA105375C2 UAA201109905A UAA201109905A UA105375C2 UA 105375 C2 UA105375 C2 UA 105375C2 UA A201109905 A UAA201109905 A UA A201109905A UA A201109905 A UAA201109905 A UA A201109905A UA 105375 C2 UA105375 C2 UA 105375C2
- Authority
- UA
- Ukraine
- Prior art keywords
- active ingredient
- suppository
- manufacture
- vaginal suppository
- ratio
- Prior art date
Links
- 238000004519 manufacturing process Methods 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- 239000006216 vaginal suppository Substances 0.000 title abstract 2
- 229940120293 vaginal suppository Drugs 0.000 title abstract 2
- 239000004480 active ingredient Substances 0.000 abstract 3
- 239000002202 Polyethylene glycol Substances 0.000 abstract 1
- 230000000843 anti-fungal effect Effects 0.000 abstract 1
- 229940121375 antifungal agent Drugs 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 229920001223 polyethylene glycol Polymers 0.000 abstract 1
- 229950008882 polysorbate Drugs 0.000 abstract 1
- 229920000136 polysorbate Polymers 0.000 abstract 1
- 239000000829 suppository Substances 0.000 abstract 1
- 239000002511 suppository base Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/02—Suppositories; Bougies; Bases therefor; Ovules
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4174—Arylalkylimidazoles, e.g. oxymetazolin, naphazoline, miconazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Об'єктом цього винаходу є спосіб виготовлення вагінального супозиторія з поліпшеною ефективністю, що містить протигрибковий активний компонент, де вказаний активний компонент присутній одночасно в розчиненій і суспендованій формах в основі супозиторія, який містить поліетиленгліколь і полісорбат. Співвідношення суспендованого і розчиненого активного компонента в супозиторії може відтворюватися, і вказане співвідношення не змінюється в ході зберігання.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
HU0900010A HU0900010D0 (en) | 2009-01-09 | 2009-01-09 | Improved pharmaceutical composition |
HU1000006A HUP1000006A2 (hu) | 2010-01-07 | 2010-01-07 | Javított hatású gyógyszerkészítmény |
PCT/HU2010/000003 WO2010079373A1 (en) | 2009-01-09 | 2010-01-08 | Improved pharmaceutical formulation |
Publications (1)
Publication Number | Publication Date |
---|---|
UA105375C2 true UA105375C2 (uk) | 2014-05-12 |
Family
ID=89989484
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
UAA201109905A UA105375C2 (uk) | 2009-01-09 | 2010-01-08 | Спосіб виготовлення вагінального супозиторія |
Country Status (5)
Country | Link |
---|---|
EP (1) | EP2385821B1 (uk) |
EA (1) | EA021943B1 (uk) |
HU (1) | HUE032022T2 (uk) |
UA (1) | UA105375C2 (uk) |
WO (1) | WO2010079373A1 (uk) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN103720638B (zh) * | 2013-12-31 | 2016-01-13 | 哈尔滨欧替药业有限公司 | 硝酸芬替康唑阴道膨胀栓及其制备方法和检测方法 |
CN105796477A (zh) * | 2014-12-29 | 2016-07-27 | 四川滇虹医药开发有限公司 | 一种硝酸布康唑栓剂及其制备方法 |
CN108210448A (zh) * | 2018-04-09 | 2018-06-29 | 翔宇药业股份有限公司 | 硝酸芬替康唑栓剂及其应用 |
CN112791048B (zh) * | 2020-12-31 | 2023-01-17 | 海南海神同洲制药有限公司 | 一种硝酸舍他康唑栓及其制备方法 |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS58152809A (ja) * | 1982-03-05 | 1983-09-10 | Eisai Co Ltd | 安定な発泡性「膣」坐剤 |
US4765978A (en) * | 1986-12-16 | 1988-08-23 | Schering Corporation | Novel vaginal suppository |
CA1337279C (en) * | 1989-06-06 | 1995-10-10 | Robert J. Borgman | Intravaginal treatment of vaginal infections with buffered metronidazole compositions |
SE9502244D0 (sv) | 1995-06-20 | 1995-06-20 | Bioglan Ab | A composition and a process for the preparation thereof |
IT1275816B1 (it) * | 1995-10-27 | 1997-10-17 | Montefarmaco Spa | Composizioni farmaceutiche solide per uso vaginale |
US20050276836A1 (en) | 1997-06-11 | 2005-12-15 | Michelle Wilson | Coated vaginal devices for vaginal delivery of therapeutically effective and/or health-promoting agents |
JP2009522360A (ja) * | 2006-01-05 | 2009-06-11 | ドラッグテック コーポレイション | 組成物およびその使用方法 |
-
2010
- 2010-01-08 WO PCT/HU2010/000003 patent/WO2010079373A1/en active Application Filing
- 2010-01-08 UA UAA201109905A patent/UA105375C2/uk unknown
- 2010-01-08 HU HUE10703346A patent/HUE032022T2/en unknown
- 2010-01-08 EA EA201190094A patent/EA021943B1/ru not_active IP Right Cessation
- 2010-01-08 EP EP10703346.6A patent/EP2385821B1/en active Active
Also Published As
Publication number | Publication date |
---|---|
EA201190094A1 (ru) | 2012-05-30 |
EP2385821A1 (en) | 2011-11-16 |
HUE032022T2 (en) | 2017-08-28 |
EA021943B1 (ru) | 2015-10-30 |
WO2010079373A1 (en) | 2010-07-15 |
EP2385821B1 (en) | 2016-08-31 |
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