TWM618118U - Test tube for placing biological specimen - Google Patents

Abstract

A test tube for loading biological samples includes a tube body integrally formed by plastic material, and an upper cover detachably arranged on the tube body. The pipe body includes a pipe wall and an extension wall. The pipe wall has an inner pipe surface defining a pipe passage, and the pipe passage has a pipe opening communicating with the outside. The extension wall is located in the pipe passage, the extension wall is connected to the inner pipe surface and surrounds and defines a grinding chamber with a closed bottom side, the top side of the grinding chamber is communicated with the pipe passage, and the extension wall It has an inner wall surface surrounding the grinding chamber, the inner wall mask has a grinding face, and the grinding face has a rough structure. The rough structure can directly grind the biological sample in the grinding chamber without changing the tube, which can simplify the processing flow of the biological sample.

Description

Test tube for loading biological samples

The present invention relates to a test tube, in particular to a test tube for containing biological samples.

Existing biological samples will be stored in a test tube containing a solvent after being collected, and then transported to the laboratory for further analysis and testing after being sealed and stored. However, before using equipment for analysis and testing, the biological sample must be taken out of the aforementioned test tube, and then placed in a glass tube to grind and break the tissue of the biological sample, so as to refine the biological sample before placing it. Into the instrument and equipment for analysis, which can improve the accuracy of the analysis.

However, the replacement process of removing the biological sample from the aforementioned test tube and putting it into the glass tube is complicated and easily contaminates the biological sample, which affects the interpretation of the test result.

Therefore, the purpose of the present invention is to provide a test tube for containing biological samples that can simplify the processing flow of biological samples.

Therefore, the test tube used for loading biological samples of the present invention contains a plastic A tube body made of one piece of material, and an upper cover. The pipe body includes a pipe wall and an extension wall. The pipe wall has an inner pipe surface surrounding an axis and defining a pipe passage. The pipe passage extends along the axis and has a pipe opening communicating with the outside. The pipe body has a top end and a bottom end oppositely arranged on the axis, and the pipe mouth is located at the top end. The extension wall is located in the pipe passage, the extension wall is connected to the inner pipe surface and surrounds and defines a grinding chamber with a closed bottom side, the top side of the grinding chamber is communicated with the pipe passage, and the extension wall It has an inner wall surface surrounding the grinding chamber, the inner wall mask has a grinding face, and the grinding face has a rough structure. The upper cover is detachably arranged on the pipe body and used to close the pipe mouth.

The effect of the present invention is that by the design of the rough structure of the grinding face, friction can be generated on the biological sample to fix its position, and it is not easy to slip off, and the uneven surface of the rough structure can also cut the biological sample. The strength and stirring force enable the biological sample to be refined and homogenized. Therefore, after placing the sampled biological sample into the tube body, the upper cover can be tightly closed to obtain good preservation, and it is also convenient to carry or transport. When performing inspection and analysis, only the upper cover is opened, and the biological sample can be directly ground in the grinding chamber without changing the tube, which simplifies the biological sample processing process and prevents the biological sample from being contaminated.

1: Tube body

100: tube channel

101: top

102: bottom

103: Nozzle

104: bottom opening

105: sample chamber

106: bottom chamber

11: pipe wall

110: Bottom

111: inner tube surface

112: Outer tube surface

113: Threaded part

114: Marking

12: Extension wall

120: Grinding chamber

121: inner wall surface

122: outer wall

123: Connect the face

124: Grind the face

125: low

126: rough structure

2: upper cover

21: inner ring wall

211: Convex

22: Outer ring wall

221: Spiral

222: ridge

23: Ring groove

α1: included angle

α2: included angle

L: axis

91: Solvent

92: Biological sample

93: Grinding Rod

The other features and effects of the present invention will be described with reference to the drawings. It is clearly presented in Fig. 1 is a three-dimensional exploded view of an embodiment of the test tube for containing biological samples of the present invention; Fig. 2 is a schematic diagram of the use of this embodiment; Fig. 3 is a cross-sectional view of this embodiment Fig. 4 is a partial cross-sectional enlarged view of this embodiment; Fig. 5 is a cross-sectional view of this embodiment; Fig. 6 is a front schematic view of pre-filling a solvent in a tube body of this embodiment; and 7 is an incomplete cross-sectional view of an upper cover of this embodiment.

1 to 3, an embodiment of the test tube for loading biological samples of the present invention is suitable for pre-filling a solvent 91, and then loading a biological sample 92 during sampling, and then using a grinding rod 93 to treat the biological sample. The sample 92 is ground and crushed to facilitate the extraction of nucleic acid. In the following description, the biological sample 92 is described as a block of biological soft tissue, but the biological sample 92 can also be of other shapes or biological hard tissues, but it is not limited to this. . When in use, the present invention can use the hand-held grinding rod 93 for manual grinding, or use a machine for automatic grinding, and the use mode is not a limitation of the present invention. The test tube for containing biological samples includes a tube body 1 and an upper cover 2.

The tube body 1 is integrally formed from a transparent plastic material. The tube body 1 has a top end 101 and a bottom end 102 that are arranged oppositely on an axis L. The tube body 1 includes a tube wall 11 and an extension wall 12. The tube wall 11 has an inner tube surface 111 surrounding the axis L, an outer tube surface 112 opposite to the inner tube surface 111, and a bottom surface 110 connected to the inner tube surface 111 and the outer tube surface 112. The inner tube surface 111 defines a tube channel 100. The tube passage 100 extends in the direction of the axis L. The tube passage 100 has a nozzle 103 at the top end 101 and communicated with the outside, and a bottom opening 104 at the bottom end 102 and opposite to the nozzle 103 . In some variations, the bottom end 102 of the tube channel 100 may omit the bottom opening 104 and be closed. The outer tube surface 112 is formed with a threaded portion 113 at the top end 101, and at least one mark 114 located between the top end 101 and the bottom end 102. As shown in FIG. 2, the number of the marks 114 is four and is equidistant. Setting, each of the markings 114 is formed by finely biting flowers to form a circle of translucent matte surface that can be used as a volume guide. In some variations, each of the markings 114 can also be a convex strip, a groove or The bumps, as long as they can be clearly identified by the operator. Since the tube body 1 is made of transparent plastic material, it is convenient for the operator to see the contents. In some variations, the threaded portion 113 and the marks 114 can also be formed on the inner tube surface 111, or even be omitted. The bottom surface 110 is located at the bottom end 102. With the arrangement of the bottom surface 110, the tube body 1 can be placed upright on a surface (not shown) such as but not limited to a desktop for easy use.

The extension wall 12 is located in the tube passage 100, and the extension wall 12 passes through the tube The channel 100 is divided into a sample chamber 105 and a bottom chamber 106. The sample chamber 105 is connected to the nozzle 103, and the bottom chamber 106 is connected to the bottom opening 104. In some embodiments, the extension wall 12 extends obliquely from the inner tube surface 111 toward the axis L and surrounds and defines a grinding chamber 120 with a closed bottom side. The top side of the grinding chamber 120 and the tube passage The sample chambers 105 of 100 are connected. In some variations, this embodiment can also omit the bottom chamber 106, that is, the bottom surface 110 is connected to the connecting surface 123 of the extension wall 12, and the extension wall 12 is exposed. In this case, only the tube body 1 Placed in a test tube rack (not shown), it can be positioned without tipping.

2 to 4, the extension wall 12 surrounds the axis L and allows the axis L to pass through. The extension wall 12 has an inner wall surface 121 surrounding the grinding chamber 120, and an inner wall surface 121 opposite to the inner surface. The wall surface 121 is the outer wall surface 122. The inner wall surface 121 has a connecting surface portion 123 extending obliquely from the inner tube surface 111 in the direction of the axis L, and a grinding surface portion 124 extending obliquely from the connecting surface portion 123 in the direction of the bottom opening 104. In some variations In this case, the inner wall surface 121 may omit the connecting surface 123. In one embodiment, the angle α1 between the connecting surface 123 and the axis L is greater than the angle α2 between the grinding surface 124 and the axis L, but in other variations, the angle α1 between the connecting surface 123 and the axis L can also be used. It is smaller than the included angle α2 between the grinding surface 124 and the axis L, as long as the included angle α1 and the included angle α2 are different to form a turning surface. In one embodiment, the grinding chamber 120 is symmetrically arranged with the axis L as the center and has a conical shape. The grinding chamber 120 has a low point 125 located on the grinding surface 124, and the low point 125 allows the axis L to communicate. pass. In some variations, the grinding surface portion 124 may also be formed only on the ring side of the inner wall surface 121. In still other variations, the grinding chamber 120 can also be cylindrical, and the grinding surface 124 can be formed on the bottom side or the ring side of the inner wall surface 121. In this embodiment, by the arrangement of the connecting surface 123, the grinding rod 93 can be guided to slide into the grinding chamber 120, and a better force application angle can be obtained. The connecting face 123 is, for example, but not limited to, a smooth surface. During the processing, the biological sample 92 overflowing the grinding chamber 120 can easily slide back into the grinding chamber 120. Therefore, the biological sample 92 can Being concentrated in the grinding chamber 120, it will not run around and the grinding effect is better.

The grinding surface 124 has a rough structure 126, by which the biological sample 92 can be directly ground in the grinding chamber 120 (see FIG. 2). The rough structure 126 in this embodiment is derived from the transfer of the mold surface , And common mold surface processing methods include polishing, electric discharge biting, potion biting, and laser biting. In this embodiment, electric discharge biting is used as an illustration. Therefore, the grinding surface 124 has a semi-transparent matte effect. In other variations, the rough structure 126 can also be formed by sandblasting, laser engraving, electrical discharge machining, or chemical etching. As long as it can produce a regular or irregular and fine uneven surface, it has a grinding effect. It should be particularly noted that, in order to prevent the biological sample 92 from being stuck in the rough structure 126 after grinding, the rough structure 126 needs to present a fine uneven surface so as not to get stuck in the fine detail after grinding. The biological sample 92 is modified, but the present invention does not limit the geometry and/or distribution area of the rough structure 126. In actual use, if it can be matched with the shape ruler of the grinding chamber 120 The grinding rod 93 with matching sizes, or the formation of a biting structure at the front end of the grinding rod 93, can further enhance the grinding effect and has the advantage of saving labor.

Referring to FIG. 3, FIG. 5 and FIG. 6, the upper cover 2 is detachably screw-locked to the tube body 1 and used to close the tube opening 103. The upper cover 2 is integrally formed of a plastic material and has an inner ring wall 21 and an outer ring wall 22 arranged at intervals around the axis L. The inner ring wall 21 and the outer ring wall 22 cooperate to form a full circumference A ring groove 23 surrounds the inner ring wall 21 and the outer ring wall 22, and the ring groove 23 allows the top end 101 of the pipe wall 11 to penetrate and join. In one embodiment, the inner surface of the outer ring wall 22 has a spiral portion 221 facing the ring groove 23, and the spiral portion 221 is used for screw connection to the threaded portion 113 of the pipe body 1. In an embodiment, the outer surface of the outer ring wall 22 has a non-slip structure composed of a plurality of convex bars 222 parallel to the axis L. When the upper cover 2 is screwed to the tube body 1, the protruding strips 222 can prevent the hand from slipping off during the tightening process. The top end 101 of the tube wall 11 penetrates into the annular groove 23 and the screw part 221 is engaged with the threaded part 113 to prevent the solvent 91 in the tube body 1 from leaking out and has a leak-proof effect. In some variations, the elastic deformability of plastic can also be used, and the width of the annular groove 23 is slightly smaller than the thickness of the tube wall 11, so that the tube body 1 and the upper cover 2 are joined in a tight-fitting manner. The upper cover 2 can be detachably arranged on the tube body 1 and has the function of facilitating storage. Therefore, the present invention does not limit the joining method or/and position of the tube body 1 and the upper cover 2.

Referring to Figures 5 and 7, the spiral portion 221 of the upper cover 2 has a double-thread structure. The inner ring wall 21 has at least one convex portion 211 facing the spiral portion 221. The at least one convex portion 211 cooperates with the spiral portion 221 and presses against the pipe wall 11 of the pipe body 1 from both sides to increase the water tightness. Effectively, the solvent 91 (see Figure 6) can be prevented from leaking during storage or transportation. The at least one convex portion 211 may be a bump, a convex strip or a bump.

Thereby, when the specimen is collected for examination, the upper cover 2 of the present invention is first opened, and the collected biological sample 92 is put into the sample chamber 105 of the tube body 1, and the biological sample 92 will be immersed in the solvent The upper cover 2 is screwed to the tube body 1 to achieve a water-tight effect to ensure that the solvent 91 and the biological sample 92 will not leak. Then, the present invention is carried or transported to an inspection room (not shown), the upper cover 2 is opened, and the grinding rod 93 is used to extend into the grinding chamber 120 for tissue grinding and refinement. The biological sample is always in the tube body 1 during the process of sampling, storage, transportation, and tissue grinding and refinement in the laboratory, and there is no need to change the tube. Therefore, the biological sample 92 can be simplified. The processing flow saves processing time. In addition, because the tube body 1 of the present invention is made of plastic material, it has the advantages of light weight and no breakage, which is not only convenient to take, but also can improve the safety of use.

In summary, the test tube of the present invention for loading biological samples, using the uneven surface of the rough structure 126 of the grinding face 124, can generate friction on the biological sample 92 and fix its position without slipping off easily. The concave-convex surface of the rough structure 126 generates cutting force and stirring force on the biological sample 92, so that the biological sample 92 can be refined and homogenized. Therefore, the present invention puts the sampled biological sample 92 into the tube body 1 After that, the upper cover 2 can be tightly closed to obtain good preservation, and it is also convenient to carry or transport. For inspection and analysis, only the upper cover 2 is opened, and the biological sample 92 can be directly processed in the grinding chamber 120 without changing the tube, which simplifies the biological sample 92 processing flow and avoids the biological sample 92. Sample 92 is contaminated. In addition, because the tube body 1 of the present invention is made of plastic material, it has the advantages of light weight and no breakage, which is not only convenient to take, but also can improve the safety of use. In this embodiment, through the inclined design of the extension wall 12 of the tube body 1, the concentration effect of the biological sample 92 in the grinding chamber 120 can be improved, so that the grinding effect is better, so it can indeed achieve the purpose of cost innovation.

However, the above are only examples of the present model, and should not be used to limit the scope of implementation of the present model, all simple equivalent changes and modifications made in accordance with the patent scope of the present model application and the contents of the patent specification still belong to This new patent covers the scope.

1: Tube body

100: tube channel

101: top

102: bottom

103: Nozzle

104: bottom opening

105: sample chamber

106: bottom chamber

11: pipe wall

111: inner tube surface

112: Outer tube surface

113: Threaded part

12: Extension wall

120: Grinding chamber

126: rough structure

2: upper cover

21: inner ring wall

22: Outer ring wall

221: Spiral

23: Ring groove

L: axis

Claims (10)

A test tube for loading biological samples, comprising: a tube body, which is integrally formed from a plastic material. The tube body includes a tube wall and an extension wall. The tube wall has an axis around an axis and defines a tube channel The tube channel extends along the axis and has a nozzle communicating with the outside. The tube body has a top end and a bottom end oppositely arranged on the axis, and the nozzle is located at the top end, The extension wall is located in the pipe passage, the extension wall is connected to the inner pipe surface and surrounds and defines a grinding chamber with a closed bottom side, the top side of the grinding chamber is communicated with the pipe passage, and the extension wall It has an inner wall surface surrounding the grinding chamber, the inner wall mask has a grinding face, and the grinding face has a rough structure; and an upper cover, which is detachably arranged on the tube body and used to close the nozzle. The test tube for containing biological samples according to claim 1, wherein the extension wall extends obliquely from the inner tube surface toward the axis, and the grinding surface of the inner wall surface surrounds the axis. The test tube for loading a biological sample according to claim 2, wherein the grinding chamber has a low point on the grinding face, and the low point is passed by the axis. The test tube for containing biological samples according to claim 3, wherein the extension wall further has a connecting surface connected to the grinding surface and extending to the inner tube surface in a direction away from the low point. The test tube for containing biological samples according to claim 4, wherein the angle between the connecting face and the axis is not equal to the angle between the grinding face and the axis. The test tube for containing biological samples according to claim 1, wherein the tube wall further has an outer tube surface opposite to the inner tube surface, and a tube connected to the inner tube surface and the outer tube surface. The bottom surface is located at the bottom end and used to stand on a surface. The test tube for containing biological samples according to claim 1, wherein the tube wall further has an outer tube surface opposite to the inner tube surface, the outer tube surface is formed with a threaded portion at the top end, the The threaded part is used for the detachable screw connection of the upper cover. The test tube for containing biological samples according to claim 1, wherein the tube channel further has a bottom opening opposite to the tube opening, and the extension wall divides the tube channel into a single chamber and a bottom A chamber, the sample chamber is connected to the nozzle, and the bottom chamber is connected to the bottom opening. The test tube for containing biological samples according to claim 1, wherein the upper cover has an inner ring wall and an outer ring wall spaced around the axis, and the inner ring wall and the outer ring wall cooperate with each other A ring groove that surrounds the inner ring wall and the outer ring wall is formed, and the ring groove is used for penetration and joining of the pipe wall. The test tube for containing biological samples according to claim 9, wherein the outer ring wall has a spiral portion for screwing the tube wall, and the inner ring wall has at least one convex portion facing the spiral portion, The at least one convex part is matched with the spiral part and presses against the pipe wall of the pipe body, thereby increasing the watertight effect.

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