TWM580681U - Various sample test piece structure - Google Patents

Abstract

The present invention discloses a multi-sample test strip structure comprising a support mat, a reaction layer, and at least one filter membrane; the present invention effectively uses a reaction unit having a plurality of reactive antibodies, and simultaneously detects the content of a plurality of different items, for example, : Pesticide content, water-containing bacteria, fecal bacteria, urine pregnancy test, etc., after the filtration of impurities is achieved, and a variety of different items and their tested concentrations can be detected at the same time, and the filter membrane can be used to pass the test solution. The impurity is filtered to improve the precision of the detection, and the support pad system is transparent, and can be double-sidedly inverted to observe the advantage of the chrominance reaction exhibited by the reaction antibody.

Description

Multi-sample test strip structure

This creation is about a multi-sample test strip structure, especially a test strip structure that can simultaneously detect a variety of different test items and their tested concentrations.

According to immunochromatography technology, it has played a very important role in today's medical system. It can be used to qualitatively or quantitatively measure changes in various biological indicators to provide reference for information such as disease diagnosis or drug treatment by inspectors or medical personnel. The vast majority of test strips on the market are designed in a qualitative manner to allow the examiner to visually know the results of the test. For example, the Republic of China Invention Patent No. I561820 "Upper and lower digestive tract cancer screening test kits and their sampling and sampling "Manipulation" and the Republic of China new patent No. M474135 "Deteriorating Arthritis Rapid Test Strips" are two of them; No. I561820 "Upper and lower digestive tract cancer screening test kits and their sampling liquids and sampling techniques" are mainly Includes a sample bottle, a test box, and a sample. The test kit is provided with an antibody-colloidal gold complex capable of binding to occult blood in the feces and H. pylori, and includes a sample tank unit and a test tank unit. The test cell unit has a first result zone, a second result zone, and at least one control zone having a control antibody that binds to the antibody to the colloidal gold complex. The sample has a pH of 8.0 and includes ingredients to aid in the detection of the components of the test cartridge to assist in binding the antibodies contained in the test cartridge to the colloidal gold complex and occult blood in the feces and H. pylori. The composition is a concentration of 10 mM tris (hydroxymethylaminomethane hydrochloride); the "Degraded Arthritis Rapid Test Paper" of M474135 is used to detect a urine sample, the rapid test paper comprises a substrate, a a detection result layer disposed on the substrate, a water absorbing layer connected to the substrate and covering the detection result layer, an antibody release layer connected to the substrate and covering the detection result layer, and a connection to the substrate Covering the sample deposition layer of the antibody release layer; the detection result layer comprises a result display segment and a control segment, the antibody release layer comprising a complex detection complex, each of the detection complexes comprising a colloidal gold particle and Multiple cartilage oligomeric matrix protein multi-strain antibodies; this rapid test strip provides a non-invasive detection method that facilitates early detection of articular cartilage degradation and early treatment to slow the rate of deterioration; however, the above two patent offices The disclosed test strip can only detect a single item and cannot simultaneously detect a plurality of different test items, and detect the concentration of the test object, The detection accuracy is low and so on; therefore, how to test the test piece by using a plurality of different reaction units to simultaneously detect the content and concentration of a plurality of different detection items by an innovative hardware design Developers and related researchers in related industries such as sales must continue to work hard to overcome and solve problems.

The reason is that the creators, in view of this, and with their rich professional knowledge and years of practical experience, have improved and created a multi-sample test strip structure, the purpose of which is to provide a test that can simultaneously detect a variety of different test items. The test strip structure whose concentration is tested and which can improve the accuracy of detection is mainly achieved by providing at least one reaction unit and dry colloidal gold on the reaction layer, and the filter film above the reaction unit is effectively effective. Filter impurities, and use a reaction unit with multiple reactive antibodies to simultaneously detect the content of a variety of different test items, such as: pesticide content, water content, fecal bacteria or urine pregnancy test, etc., can achieve simultaneous detection of a variety of different The detection item and its tested concentration, and the filter membrane can filter the impurities in the liquid to be tested, thereby improving the accuracy of the detection.

According to the purpose of the present invention, a multi-sample test strip structure is proposed, which comprises at least a support mat body, a reaction layer, and at least one filter membrane; the support mat body is a transparent body; the reaction layer is affixed On the surface of one of the support mats, wherein the reaction layer is provided with at least one reaction unit having a plurality of reactive antibodies; the filter is disposed on the other surface of the reaction layer relative to the support mat, the filter The membrane surface is provided with at least one pair of instillation marks to be reacted, wherein the filter is attached to the reaction layer by an adhesive layer disposed on at least one side of the reaction layer.

In an embodiment of the present invention, a first dropper is further disposed to store the test liquid, and the test liquid contains a plurality of colloidal gold.

In an embodiment of the present invention, a first dropper and a second dropper are further disposed, the first dropper stores a liquid to be tested, and the second dropper stores a quantity of the solution, and The solution contains a plurality of colloidal gold, and the second dropper has a liquid outlet.

In an embodiment of the present invention, a first dropper and a second dropper are further disposed, the first dropper stores a liquid to be tested, and the second dropper stores a quantity of the solution, and The second dropper has a liquid outlet, and the support pad is provided with an antibody layer disposed on one side of the reaction layer, and the antibody layer is provided with a plurality of dry colloidal gold.

In one embodiment of the present invention, the support pad body is provided with a liquid absorbing layer, and the liquid absorbing layer is adjacent to the reaction layer and attached to the support pad body, and is opposite to the antibody layer.

In one embodiment of the present invention, the reaction layer is attached to one surface of the support pad body and has a bare region on at least one side of the surface of the reaction layer.

In one embodiment of the present creation, the instillation indicia can be a colored symbolic logo or a marked line.

In one embodiment of the present invention, a pre-cut line is disposed adjacent the end of the filter layer.

In one embodiment of the present invention, the filter membrane is provided with a hand tearing section near the end of the reaction layer.

Therefore, the multi-sample test strip structure of the present invention mainly adopts the design of at least one reaction unit and dry colloidal gold on the reaction layer, and effectively uses a reaction unit having a plurality of reactive antibodies to simultaneously detect the content of a plurality of different test items. For example, the pesticide content, the water-containing bacteria content, the fecal bacteria-containing amount or the urine pregnancy test, etc., can achieve simultaneous detection of a plurality of different test items and their tested concentrations, and the support pad system is a transparent body, which is turned over. It is also possible to directly examine the advantages of observing the chroma reaction exhibited by the reacted antibody.

In order to understand the technical characteristics, content and advantages of the creation and the effects that can be achieved by the examiner, the author will use the drawings in detail and explain the following in the form of the examples, and the drawings used therein The subject matter is only for the purpose of illustration and supplementary instructions. It is not necessarily the true proportion and precise configuration after the implementation of the original creation. Therefore, the proportions and configuration relationships of the attached drawings should not be interpreted or limited in the actual implementation scope. First described.

First, please refer to FIG. 1 to FIG. 4 together, which is a multi-sample test strip structure of the present invention. The multi-sample test strip structure includes at least one support mat body (10) and a reaction layer. (20), and at least one filter (30).

The support pad body (10) is a transparent body;

The reaction layer (20) is attached to one surface of the support pad body (10), wherein the reaction layer (20) is provided with at least one reaction unit (21) having a plurality of reactive antibodies (211); The reaction unit (21) is a color reaction zone; in a preferred embodiment of the present invention, the reaction layer (20) is attached to one surface of the support pad (10), and the support pad is The surface of the body (10) has a bare region (22) on at least one side, and the reaction layer (20) is provided with three reaction units (21) having a plurality of reactive antibodies (211), and the three reactions The unit (21) may be the same or different reaction antibody (211), and may simultaneously detect a plurality of test liquids or simultaneously detect a plurality of different test items, for example, pesticide residues of vegetables, bacteria contained in water quality, and feces. Containing bacteria or urine pregnancy test.

The filter membrane (30) is disposed on the other surface of the reaction layer (20) with respect to the support pad body (10), and the surface of the filter membrane (30) is provided with at least one pair of reaction units (21). The instillation mark (31), wherein the filter film (30) is provided on at least one side of the reaction layer (20) by an adhesive layer (32) to attach the reaction layer (20); In a preferred embodiment, the filter (30) is disposed on a surface of the reaction layer (20) with respect to the support pad (10), and the filter (30) is attached by the adhesive layer (32). On the surface of the reaction layer (20), the filter membrane (30) is provided with a drip mark (31) corresponding to the position of the reaction unit (21), and at least one first dropper (40) is attached to the filter. (30) dropping a test liquid (42) having a plurality of analytes (43), and the filter membrane (30) is capable of filtering impurities (45) of the analyte (43) (as shown in Fig. 4). The reaction layer (20) can be provided with a plurality of layers (30) at the same time, and the liquid (42) with more impurities (45) can improve the filtration degree, and the detection result can be more accurate. In addition, the instillation mark (31) may be a colored symbol mark (311) or a mark line (312), and the symbol mark (311) may be a circular mark, or a triangular mark, or The square mark, or the cross mark, or the star mark, helps the first liquid outlet (41) of the first dropper (40) to be directly and accurately aligned, so that the test liquid is dropped. (42) Penetrating absorption by directly responding to the reaction unit (21).

In the first embodiment of the present invention, please refer to FIG. 4 together, the first dropper (40) stores the test liquid (42), and the test liquid (42) is provided with a plurality of colloidal gold (44). . In the embodiment, the reaction layer (20) is provided with three reaction units (21) having a plurality of reactive antibodies (211). When the detection is performed, three first dropper (40) are taken, and the first The liquid outlet (41) can directly and accurately align the instillation mark (31), and the test liquid (42) containing the test object (43) is dropped on the filter film (30) to enable the test liquid ( 42) the impurity (45) is first filtered in the filter membrane (30), and the test liquid (42) and the test object (43) and the colloidal gold (44) are infiltrated directly through the filter membrane (30). Absorbed by the reaction unit (21), the analyte (43) is combined with the reaction antibody (211), and the analyte (43) is in the reaction unit (21) by the colloidal gold. (44) and exhibiting chromaticity, the reaction unit (21) is presented in different chromaticities depending on the amount of binding of the analyte (43), and the tester can not only transmit the chromaticity exhibited by the reaction antibody (211). Detecting whether the detected item is normal or not, and the colloidal gold (44) is quantitatively set in the measured liquid (42), and the content concentration of the measured object (43) can be measured, and the main detection is as long as it contains plural The first dropper (40) of the colloidal gold (44) is directly The multi-sample detection test piece structure can be used to detect the chromaticity, and the rapid detection and operation are easy; further, the impurity (45) in the test liquid (42) can be filtered through the filter film (30). Helps improve the accuracy of detection. Further, the filter film (30) is provided with a pre-cut line (33) near the end of the reaction layer (20). When the color chromaticity of the reaction unit (21) is to be examined, the filter film (30) can be self-predicted. The cut line (33) is peeled off the reaction layer (20), and the chromaticity of the reaction unit (21) can be examined by the reaction layer (20). Alternatively, the filter membrane (30) is provided with a hand tearing section (34) near the end of the reaction layer (20), and the filter membrane (30) is peeled off the reaction layer (20) by the tearing section (34). The chromaticity of the reaction unit (21) can be examined by the reaction layer (20). In addition, the support pad body (10) is a transparent body, and the color of the reaction antibody (211) of the reaction layer (20) can also be turned directly to the support pad body (10). The inspection is carried out to achieve the convenience of double-sided inspection of the chrominance reaction exhibited by the reaction unit (21).

In the second embodiment of the present invention, please refer to FIG. 5 and FIG. 6 together, the first dropper (40) stores the liquid to be tested (42), and is stored by a second dropper (50). A quantity of solution (51), and the solution (51) contains a plurality of colloidal gold (52). When the test is performed, three first droppers (40) are taken, and the first liquid outlet (41) can directly and accurately align the instillation mark (31), and the measured object (43) is tested. The liquid (42) is dropped on the filter membrane (30), and the impurity (45) of the test liquid (42) is first filtered on the filter membrane (30), and then the liquid to be tested (42) and the measured liquid are tested. The substance (43) permeates through the filter membrane (30) and is directly absorbed by the reaction unit (21) and allowed to stand, allowing the analyte (43) to react with the reaction antibody (211); a second dropper (50) from which the solution (51) containing a plurality of colloidal gold (52) can be directly dropped into the bare zone (22), and the object to be tested (43) The reaction unit (21) exhibits chromaticity by the colloidal gold (52), and the reaction unit (21) is presented in different chromaticities depending on the amount of the analyte (43) combined, and the tester can not only The chromaticity exhibited by the reaction antibody (211) is used to detect whether the detected item is normal or not, and the colloidal gold (52) is quantitatively disposed in the solution (51), and the measured object can be detected (43). Content concentration; and the impurity (45) in the liquid to be tested (42) can pass through the filter (30) Filtration helps to improve the accuracy of the test. Further, the filter film (30) is provided with a pre-cut line (33) near the end of the reaction layer (20). When the color chromaticity of the reaction unit (21) is to be examined, the filter film (30) can be self-predicted. The cut line (33) is peeled off the reaction layer (20), and the chromaticity of the reaction unit (21) can be examined by the reaction layer (20). In addition, the support pad body (10) is a transparent body, and the color of the reaction antibody (211) of the reaction layer (20) can also be turned directly to the support pad body (10). The inspection is carried out to achieve the convenience of double-sided inspection of the chrominance reaction exhibited by the reaction unit (21).

In the third embodiment of the present invention, referring to FIG. 5 and FIG. 7, the first dropper (40) stores the measured liquid (42), and the second dropper (50) stores a certain amount of the solution. (51), the support pad body (10) is provided with an antibody layer (60), the antibody layer (60) is disposed on one side of the reaction layer (20), and the antibody layer (60) is provided with a plurality of dry colloids. Kim (61). When the detection is performed, three first dropper (40) are taken, and the first liquid outlet (41) can directly and accurately align the symbol (311), and the measured object (43) is tested. The liquid (42) is dropped on the filter membrane (30), and the impurity (45) of the test liquid (42) is first filtered on the filter membrane (30), and then the liquid to be tested (42) and the measured liquid are tested. The substance (43) permeates through the filter membrane (30) and is directly absorbed by the reaction unit (21) and allowed to stand, allowing the analyte (43) to react with the reaction antibody (211); a two dropper (50) from which the solution (51) can be directly dropped into the bare zone (22), and the plurality of dry colloidal gold (61) can follow the solution ( 51) flowing to the reaction layer (20), and further the object (43) exhibits chromaticity in the reaction unit (21) by the plurality of dry colloidal gold (61), and the reaction unit (21) is The measured substance (43) is present in different chromaticities, and the tester can not only detect the normality of the detected item by the chromaticity exhibited by the reaction antibody (211), but also the plurality of dry colloidal gold. (61) is quantitatively disposed on the antibody layer (60), and the measured object can be detected (43) The content concentration; and the impurity (45) in the liquid to be tested (42) can be filtered through the filter (30), which helps to improve the accuracy of the detection. Further, the filter film (30) is provided with a pre-cut line (33) near the end of the reaction layer (20). When the color chromaticity of the reaction unit (21) is to be examined, the filter film (30) can be self-predicted. The cut line (33) is peeled off the reaction layer (20), and the chromaticity of the reaction unit (21) can be examined by the reaction layer (20). In addition, the support pad body (10) is a transparent body, and the color of the reaction antibody (211) of the reaction layer (20) can also be turned directly to the support pad body (10). The inspection is carried out to achieve the convenience of double-sided inspection of the chrominance reaction exhibited by the reaction unit (21).

It can be seen from the above description that the present invention has the following advantages compared with the prior art and the product:

1. The multi-sample test strip structure of this creation is mainly made by the drip mark to make the first dropper accurately aligned directly with the reaction layer.

2. The multi-sample test strip structure of the present invention can filter the impurities in the test liquid through the filter membrane, which helps to improve the accuracy of detection.

3. In the multi-sample test strip structure of the present invention, the support mat body is a transparent body, which can achieve the convenience of double-sided inspection of the chrominance reaction exhibited by the reaction unit.

In summary, the multi-sample test strip structure of the present invention can achieve the intended use effect by the above disclosed embodiments, and the creation has not been disclosed before the application, and has completely complied with the patent law. Regulations and requirements.提出Issuing an application for the creation of a patent in accordance with the law, and asking for a review, and granting a patent, it is really sensible.

However, the illustrations and descriptions disclosed above are only preferred embodiments of the present invention, and are not intended to limit the scope of protection of the present invention; those who are familiar with the skill are otherwise characterized by the scope of the creation. Equivalent changes or modifications shall be considered as not departing from the design of this creation.

(10) ‧‧‧Support pad

(20) ‧‧‧Reaction layer

(21) ‧‧‧Reaction unit

(211)‧‧‧Reactive antibodies

(22)‧‧‧Naked area

(30) ‧ ‧ filter

(31)‧‧‧Drip marks

(311) ‧ ‧ symbolic

(312)‧‧‧Marking line

(32) ‧‧‧Adhesive layer

(33) ‧‧‧Pre-cut line

(34) ‧‧‧Hand tearing segment

(40)‧‧‧First dropper

(41)‧‧‧First outlet

(42)‧‧‧Measured liquid

(43) ‧‧‧Measured objects

(44) ‧‧‧colloidal gold

(45) ‧ ‧ impurities

(50)‧‧‧Second dropper

(51) ‧‧‧solution

(52) ‧‧‧colloidal gold

(53) ‧‧‧Second outlet

(60) ‧ ‧ antibody layer

(61) ‧‧‧Dry colloidal gold

(70) ‧ ‧ absorbing layer

Figure 1: Schematic diagram of the overall device decomposition of the multi-sample test strip structure. Figure 2: A cross-sectional view of the overall device of the multi-sample test strip structure of the present creation. Figure 3: The overall device appearance combination diagram of the multi-sample test strip structure of the present creation. Fig. 4 is a schematic view showing the use of the first embodiment of the multi-sample test strip structure of the present invention. Figure 5: The second embodiment of the present multi-sample test strip structure is shown in Figure (1). Figure 6: Schematic diagram (2) of the second embodiment of the multi-sample test strip structure of the present invention. Fig. 7 is a schematic view showing the use of the second embodiment of the multi-sample test strip structure of the present invention.

Claims (9)

A multi-sample test strip structure, the multi-sample test strip structure comprises at least: a support mat body (10), which is a transparent body; and a reaction layer (20) attached to the support mat a surface of one of the bodies (10), wherein the reaction layer (20) is provided with at least one reaction unit (21) having a plurality of reactive antibodies (211); at least one filter (30) relative to the support pad (10) is disposed on the other surface of the reaction layer (20), and the surface of the filter film (30) is provided with at least one pair of instillation marks (31) to be reacted to the reaction unit (21), wherein the filter film (30) ) is attached to at least one side of the reaction layer (20) by an adhesive layer (32). For example, the multi-sample test strip structure described in claim 1 is further provided, wherein the multi-sample test strip structure is provided with a first dropper (40) having a first liquid outlet (41), which is stored There is a liquid to be tested (42), and the liquid to be tested (42) is provided with a plurality of analytes (43) and a plurality of colloidal gold (44). For example, the multi-sample test strip structure described in claim 1 is further provided, wherein the multi-sample test strip structure is provided with a first dropper (40), and the test liquid (42) is stored, the measured The liquid (42) is provided with the test object (43); and, a second dropper (50) is stored with a certain amount of the solution (51), and the solution (51) contains a plurality of colloidal gold (52). And the second dropper (50) has a second liquid outlet (53). For example, the multi-sample test strip structure described in claim 1 is further provided, wherein the multi-sample test strip structure is provided with a first dropper (40), and the test liquid (42) is stored, the measured The liquid (42) is provided with the object to be tested (43); and a second dropper (50) is stored a solution (51), and the second dropper (50) has a second liquid outlet (53); wherein the support pad (10) is provided with an antibody layer (60), and the antibody layer (60) is provided On one side of the reaction layer (20), the antibody layer (60) is provided with a plurality of dry colloidal gold (61). The multi-sample test strip structure as described in claim 3 or 4, wherein the reaction layer (20) is attached to one surface of the support mat (10) and the surface of the reaction layer (20) is applied At least one side has a bare area (22). The multi-sample test strip structure as described in claim 4, wherein the support mat body (10) is provided with a liquid absorbing layer (70) adjacent to the reaction layer (20). The support pad body (10) is disposed on the other side of the antibody layer (60). The multi-sample test strip structure according to any one of claims 1 to 4, wherein the drip mark (31) may be a colored symbol mark (311) or a mark line (312). And the symbol (311) can be a circular flag, or a triangular flag, or a square flag, or a cross-shaped flag, or a star-shaped flag. The multi-sample test strip structure according to any one of claims 1 to 4, wherein the filter membrane (30) is provided with a pre-cut line (33) near the end of the reaction layer (20). The multi-sample test strip structure according to any one of claims 1 to 4, wherein the filter membrane (30) is provided with a hand tearing section (34) near the end of the reaction layer (20).