TWM445982U - Capsule health care structure with antrodia camphorata extract - Google Patents

Description

Capsule health care structure with Antrodia camphorata extract

The present invention relates to a capsule health care structure with an extract of Antrodia camphorata, in particular, a method for filling an Anthraquinone extract into a capsule so that it can be stored in a normal state, and not only avoids contact with air, but also has better The capsule health care structure with the storage stability and at the same time, which is convenient for the user to carry, take and absorb.

With the development of social diversification and the increasing pressure on people's economy and work pressure, drinking has become a common behavior. The opportunities for drinking are increasing in business receptions, social gatherings between colleagues or acquaintances, family gatherings, etc. Many people suffer from hangovers due to frequent drinking and drinking, which in turn affects the normal working life of the next day; hangovers are a general term for physical and mental discomfort after drinking, and their objective symptoms are cognitive decline. Nausea, vomiting, headache, decreased exercise capacity, etc.

Although the cause of the hangover has not been fully studied, there are many academic opinions that the cause is the reaction caused by the toxic effects of alcohol and alcohol metabolites (acetaldehyde, formaldehyde, acetone); The main ingredient is alcohol, so when drinking alcohol, alcohol will be distributed rapidly with the blood. For organs and cells of the human body, alcohol is toxic and needs to be metabolized through a series of chemical reactions. Understand the metabolic mechanism of the human body, a small part of alcohol can be discharged through breathing or urine, and the remaining 90~95% Alcohol is converted into acetaldehyde by alcohol dehydrogenase (ADH) in the liver, and acetaldehyde is excreted into acetic acid, carbon dioxide and water by aldehyde dehydrogenase (ALHD); For those skilled in the art, it is a reasonable inference to accelerate the metabolic elimination of alcohol by increasing the specific activity of the alcohol dehydrogenase used to metabolize alcohol in the body.

Antrodia camphorata is a kind of wild mushroom, a very precious and endemic herbaceous plant in Taiwan's forests. The early legend was that Taiwanese aborigines discovered the Antrodia on the burdock tree when they were harvesting. Because of life style or Lotte personality, it is inevitable to like drinking and hangover; however, after drinking the cooking liquid of Antrodia, it has found that it has the effect of hangover, making Antrodia a traditional precious medicine of the aborigines. In the past few years, due to its extensive pharmacological activity and low toxicity, Antrodia has been paid more and more attention in the international arena. The extraction of natural products with medicinal effects by Antrodia is also valued by scholars and the industry. Based on the above various factors, it is quite feasible to use the extract of Antrodia camphorata as a component to lower the concentration of blood alcohol to improve the symptoms of hangover. However, most of the current manufacturers use Aconite to make mycelium powder of Antrodia camphorata. For consumers to take a small amount of warm (hot) boiled water and mix well, or use hot water to cook, alcohol and take it after taking it; this not only reduces the efficacy of Antrodia, but also makes it difficult for users. And problems with taking inconveniences.

Nowadays, the creator is still in the light of the lack of practicality in the implementation of the above-mentioned existing 樟 ,, so it is a tireless spirit, and is improved by its rich professional knowledge and years of practical experience, and accordingly Research and creation of this creation.

The main purpose of this creation is to provide a kind of extracting the Antrodia camphorata extract into the capsule so that it can be stored in the capsule at the same time, which not only avoids contact with the air, but also has better preservation property, and can be conveniently carried and taken by the user. A capsule health care structure that facilitates absorption of the extract of Antrodia camphorata.

In order to achieve the above-mentioned object, the present inventors propose a capsule health care structure with an extract of Antrodia camphorata, which comprises a pair of capsule bodies, which are made of edible grade gummy raw materials, and the pair of capsule bodies are respectively a concave groove is formed in the concave shape, and the pair of capsule systems are covered with each other by the opening of the groove, and an accommodation space is formed after the cover; and an appropriate amount of the Antrodia camphorata extract liquid is filled in the accommodating space; Antrodia extract is an active ingredient of Antrodin B and Antrodin C compounds extracted from the cell wall of the ruptured mycelium of Antrodia camphorata, and mixed with an edible oil to form a solution, among which Antrodin B and Antrodin C are Malayan. The derivative of the amine; thereby, the capsule health care structure of the present invention has the advantages and functions of being convenient to carry, take and absorb, and the Antrodia camphora extract is not easy to react with the external environment. Deterioration, with better preservation.

a capsule health care structure with an extract of Antrodia camphorata as described above, wherein the pair A capsule is provided at the lid of the capsule body. When stored in a normal position, it can not only avoid the exudation of the Antrodia camphorata extract in the capsule body, but also avoid contact with the air, so there is no doubt about oxidative deterioration.

The capsule health care structure of the Antrodia camphorata extract as described above, wherein the above-mentioned paired capsule system is integrally formed.

The capsule health care structure with the anthraquinone extract as described above, wherein the edible oil may be selected from the group consisting of medium chain triglyceride, corn oil, olive oil, soybean oil, safflower seed oil, cottonseed oil, peanut oil, sesame oil, sunflower oil , a group of grape seed oil and a mixture thereof.

The purpose of this creation and its structural and functional advantages will be explained in accordance with the structure shown in the following figure, in conjunction with specific examples, so that the review committee can have a deeper and more specific understanding of the creation.

First, referring to the first to second figures, respectively, is a perspective cross-sectional view and a plan sectional view of a preferred embodiment of the capsule health care structure of the present invention. The capsule health care structure mainly comprises a pair of capsule bodies ( 1) The pair of capsule bodies (1) are made of an edible grade of colloidal material, and the pair of capsule bodies (1) are respectively concavely formed to form a groove (11), and the pair of capsule bodies (1) The cover is closed with the opening of the recess (11), and an accommodating space is formed after the cover; and an appropriate amount of the Antrodia camphora extract (2) is filled in the accommodating space; wherein, in this embodiment, A film (3) is provided on the cover of the capsule body (1), and the storage of the Antrodia camphorata in the capsule body (1) can be avoided not only during storage and storage. (2) Exudation can also avoid contact with air, so there is no doubt about oxidative deterioration. It is worth noting that the above-mentioned Antrodia camphorata extract (2) is Antrodin B extracted from the cell wall of the ruptured mycelium of Antrodia camphorata. And Antrodin C compound as an active ingredient, and mixed with an edible oil in the form of a solution, wherein Antrodin B and Antrodin C are derivatives of maleimide and maleic anhydride dervatives; wherein the edible oil is selected from the group consisting of Medium-chain triglyceride (MCT oil), corn oil, olive oil, soybean oil, safflower seed oil, cottonseed oil, peanut oil, sesame oil, sunflower oil, grape seed oil, and the like Group of.

In addition, referring to the third to fourth figures, respectively, a perspective view and a plan cross-sectional view of a preferred embodiment of the present invention for creating a capsule health care structure of the Antrodia camphorata extract, in the present embodiment, the pair of capsule bodies ( 1) One-piece molding.

It is worth noting that the artificial extract of Antrodia camphorata is based on the mycelium powder of Antrodia camphorata. After breaking the cells, the Antrodin B and Antrodin C in the cell wall of Antrodia camphorata are purified by oil extraction technique. Dissolving it in edible oil has better absorption rate and efficacy relative to the powdered Antrodia mycelium system; in addition, according to the following experiment, it is confirmed that it has a significant increase in alcohol dehydrogenase specific activity and lowers blood alcohol The effect of concentration.

First, the loss of righting reflex (LORR) test of the white mouse; this creation The tested ICR strains each weigh 26 to 30 grams, have a feeding temperature of 25 ± 1 ° C, a relative humidity of 65 ± 5%, and maintain a 12-hour switching light dark cycle to a standard laboratory. Graded feed (Laboratory Rodent Diet, PMT Feed, St. Louis, USA) is fed, and feed and water supply are not restricted during feeding; the feeding conditions of the white mice are in accordance with the relevant experimental animal management guidelines announced by the National Institutes of Health; After all the white mice were fasted for 12 hours, they were randomly divided into two groups, one group was the control group and the other group was the experimental group, each group had at least 4 white mice; the test mode was small in the control group. The white rat mouth was fed with 0.2 or 0.3 ml of sterile distilled water, and the white mice in the experimental group were fed 0.2 or 0.3 ml of the capsule health care structure with the antrodia camphorata extract; after 30 minutes, the above small The white rat mouth was fed with 0.3 ml of 52% alcohol, and the loss of positive reaction of the white mice was observed. Please refer to the fifth figure for the whitening of alcohol fed with sterile distilled water and Antrodia camphorata extract. Rats lose their positive response A schematic diagram of the effect between the two, it can be clearly seen from the figure that the white mice fed the artificial extract of Antrodia camphorata did not lose the righteous reaction, while the white mice fed only sterile distilled water lost the positive reaction time according to the feeding amount. The difference is about 15~18 minutes, and the results are summarized as follows. From this result, it can be inferred that the artificial extract of Antrodia camphorata has a significant effect on restoring wakingness to white mice after eating alcohol; The time of the reaction was to turn the white mouse over so that the belly was facing up and record the time it took to correct the correction.

Furthermore, the blood alcohol concentration and the alcohol dehydrogenase specific activity of the white mice were analyzed. Similarly, the ICR strain of the test each weighed 26 to 30 grams, and the feeding temperature was 25 ±1 ° C, relative humidity of 65 ± 5%, and maintained in 12 hours of light, 12 hours of dark physiological conditions, fed with standard laboratory grade feed, no restriction on feed and water supply during feeding; feeding of small white mice The conditions were followed in accordance with the relevant guidelines for the management of experimental animals announced by the National Institutes of Health. After all the white rats were fasted for 12 hours, they were randomly divided into five groups: control group, Antrodia camphorata extract group, sterile distilled water group, and alcohol. + Sterile distilled water group, and alcohol + Antrodia camphorata extract group, each group has at least 3 white mice; among them, the control group does not provide any feeding, and the extract of Zhizhi extract is 0.3ml. The capsule health care structure of the extract of Zhizhi extract and the sterile distilled water group were fed with 0.3 ml of sterile distilled water, alcohol + sterile distilled water, and 0.3 ml of sterile distilled water was applied to the mouth. After 30 minutes, the feeding volume was 100. The alcohol content of the 52% alcohol is 0.3 ml, and the alcohol + Antrodia extract is 0.3 ml of the original Antrodia camphorata extract. After 30 minutes, the volume of the feed is 52. % of alcohol 0.3ml; this test mode is 60 minutes after feeding, analysis of the alcohol concentration in the serum of white mice and alcohol dehydrogenase specific activity, please refer to the sixth figure, is the experimental group without oral feeding The effect of the alcohol dehydrogenase activity in the white mice was measured (including the control group). It can be clearly seen from the figure that the anthraquinone extract of the present invention can actually increase the specific activity of alcohol dehydrogenase in the white mice. Please refer to the seventh figure, the experimental group for oral alcohol test shows the effect of alcohol dehydrogenase activity in white mice, compared with the sixth picture, in line with the current alcohol metabolism requires alcohol The dehydrogenase decomposes to accelerate decomposition to acetaldehyde, and the whitening mice fed the artificial extract of Antrodia camphorata significantly increase the specific activity of alcohol dehydrogenase in the body (~50%); According to the current alcohol metabolism inference, alcohol is mainly absorbed by the digestive tract. 90~95% of the alcohol absorbed into the body is metabolized in the liver, and the remaining 5-10% are excreted through exhalation, urine and sweat. Blood entering the liver The alcohol is oxidized to acetaldehyde by the alcohol dehydrogenase produced by the liver, and the acetaldehyde is oxidized by acetaldehyde dehydrogenase into acetic acid which is harmless to the body and excreted; thus, it can be reasonably inferred that the original Antrodia extract is indeed It can increase the alcohol dehydrogenase specific activity, thereby reducing the effect of alcohol concentration in the blood; please refer to the eighth figure, the effect of measuring the blood alcohol concentration of the white mice for all experimental groups (including the control group), feeding the creation In the white mice of Zhizhi extract, the blood alcohol concentration was significantly lower (~45%); it is worth noting that although the pharmacological machine of the original Zhizhi extract was not clearly established, it is reasonable to infer The creation of the Antrodia camphorata extract can increase the alcohol dehydrogenase specific activity responsible for alcohol metabolism, Alcohol metabolism reduces blood alcohol levels.

It can be seen from the above description that the present creation has the following advantages compared with the prior art:

1. The capsule health care structure of the present invention is filled with the extract of Antrodia camphorata in the capsule. Compared with the traditional Antrogen powder, or cooked in hot water or alcohol, the user is not only convenient to carry. In addition to the advantages and effects of taking and benefiting absorption, the extract of Antrodia camphorata is not easy to react with the external environment and deteriorates, and has the effect of better preservation.

2. The capsule health care structure of the Zhizhi extract can stimulate the alcohol dehydrogenase of the liver to alcohol metabolism after drinking, and can be reduced at a faster rate than the extract of the anthraquinone which is not administered to the present invention. Blood alcohol concentration, thus reducing the toxic effects of alcohol.

3. The capsule health care structure of the present invention is further subjected to an animal test for the component which is expected to have a blood alcohol concentration lower, and specifically supports the effect of reducing the blood alcohol concentration after consumption of the alcoholic substance.

In summary, the capsule health care structure of the present invention can achieve the intended use effect by the above disclosed embodiments, and the creation has not been disclosed before the application, and has been fully met. The provisions and requirements of the Patent Law. If you apply for a new type of patent in accordance with the law, you are welcome to review it and grant a patent.

However, the illustrations and descriptions disclosed above are only preferred embodiments of the present invention, and are not intended to limit the scope of protection of the present invention; Other equivalent changes or modifications made in accordance with the characteristics of this creation shall be considered as not departing from the scope of the design of this creation.

(1) ‧ ‧ capsule body

(11) ‧‧‧ grooves

(2)‧‧‧ Antrodia extract

(3) ‧ ‧ seal film

First Figure: Appearance perspective view of a preferred embodiment of the present invention

Second Figure: A plan sectional view of a preferred embodiment of the present invention

Third figure: an external perspective view of the second preferred embodiment of the present invention

Figure 4: A plan sectional view of the second preferred embodiment of the present invention

Figure 5: Schematic diagram of the effect of loss of righting reaction time on white rats fed with alcohol by using sterile distilled water and Antrodia camphorata extract

Figure 6: Schematic diagram of the effect of alcohol dehydrogenase (ADH) on the activity of white mice in the experimental group (including the control group)

Figure 7: The effect of the alcohol dehydrogenase (ADH) specific activity in the white mice tested by the experimental group

Figure 8: Schematic diagram of the effect of blood alcohol concentration on white mice in all experimental groups (including the control group)

(1) ‧ ‧ capsule body

(11) ‧‧‧ grooves

(2)‧‧‧ Antrodia extract

(3) ‧ ‧ seal film

Claims (4)

A capsule health care structure with an extract of Antrodia camphorata, comprising a pair of capsule bodies, the pair of capsule systems being made of an edible grade of gelatinous material, wherein the pair of capsule bodies are respectively concave and concave, and the groove body is formed The capsule system is covered with the opening of the groove, and an accommodating space is formed after the lidping; and an appropriate amount of the extract of Antrodia camphorata, the extract of the Antrodia camphorata is filled in the accommodating space, and the Antrodia camphorata extract is Antrodin B and Antrodin C compounds extracted from the cell wall of the mycelium of the mycelium of Antrodia camphorata as an active ingredient, and mixed with an edible oil in a solution, wherein Antrodin B and Antrodin C are maleimide and maleic anhydride. Derivatives) derivatives. The capsule health care structure of the Antrodia camphorata extract according to the first aspect of the invention, wherein the capsule body has a film at the cover. The capsule health care structure of the Antrodia camphorata extract according to the first aspect of the invention, wherein the capsule system is integrally formed. The capsule health care structure of the Antrodia camphorata extract according to the first aspect of the invention, wherein the edible oil is selected from the group consisting of medium-chain triglyceride (MCT oil), corn oil, olive oil, and large A group consisting of soybean oil, safflower oil, cottonseed oil, peanut oil, sesame oil, sunflower oil, grape seed oil, and the like.