TWI895534B - 特別用於玻璃體內流體給藥的給藥裝置 - Google Patents

特別用於玻璃體內流體給藥的給藥裝置

Info

Publication number
TWI895534B
TWI895534B TW110140312A TW110140312A TWI895534B TW I895534 B TWI895534 B TW I895534B TW 110140312 A TW110140312 A TW 110140312A TW 110140312 A TW110140312 A TW 110140312A TW I895534 B TWI895534 B TW I895534B
Authority
TW
Taiwan
Prior art keywords
actuating
main unit
dosing
primary
drive spring
Prior art date
Application number
TW110140312A
Other languages
English (en)
Chinese (zh)
Other versions
TW202233140A (zh
Inventor
亞瑟 羅斯
史蒂芬 舒伊
華森 班傑明 哈利 庫利斯
羅奇考斯特 安德魯 蓋 拉巴特
阿拉姆 賈瓦達特 卡塔爾
保羅 葛拉漢 海頓
奧利佛 大衛 弗格
Original Assignee
德商百靈佳殷格翰國際股份有限公司
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 德商百靈佳殷格翰國際股份有限公司 filed Critical 德商百靈佳殷格翰國際股份有限公司
Publication of TW202233140A publication Critical patent/TW202233140A/zh
Application granted granted Critical
Publication of TWI895534B publication Critical patent/TWI895534B/zh

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00Methods or devices for treatment of the eyes; Devices for putting in contact-lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/0008Introducing ophthalmic products into the ocular cavity or retaining products therein
    • A61F9/0017Introducing ophthalmic products into the ocular cavity or retaining products therein implantable in, or in contact with, the eye, e.g. ocular inserts
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00Methods or devices for treatment of the eyes; Devices for putting in contact-lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/0008Introducing ophthalmic products into the ocular cavity or retaining products therein
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/20Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • A61M5/2033Spring-loaded one-shot injectors with or without automatic needle insertion
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/3146Priming, e.g. purging, reducing backlash or clearance
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/315Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31565Administration mechanisms, i.e. constructional features, modes of administering a dose
    • A61M5/31566Means improving security or handling thereof
    • A61M5/31571Means preventing accidental administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/315Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31565Administration mechanisms, i.e. constructional features, modes of administering a dose
    • A61M5/31576Constructional features or modes of drive mechanisms for piston rods
    • A61M5/31578Constructional features or modes of drive mechanisms for piston rods based on axial translation, i.e. components directly operatively associated and axially moved with plunger rod
    • A61M5/31581Constructional features or modes of drive mechanisms for piston rods based on axial translation, i.e. components directly operatively associated and axially moved with plunger rod performed by rotationally moving or pivoting actuator operated by user, e.g. an injection lever or handle
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/50Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests having means for preventing re-use, or for indicating if defective, used, tampered with or unsterile
    • A61M5/5086Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests having means for preventing re-use, or for indicating if defective, used, tampered with or unsterile for indicating if defective, used, tampered with or unsterile
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/20Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • A61M2005/2073Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically preventing premature release, e.g. by making use of a safety lock
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/315Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31501Means for blocking or restricting the movement of the rod or piston
    • A61M2005/31508Means for blocking or restricting the movement of the rod or piston provided on the piston-rod
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/50Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests having means for preventing re-use, or for indicating if defective, used, tampered with or unsterile
    • A61M5/5013Means for blocking the piston or the fluid passageway to prevent illegal refilling of a syringe
    • A61M5/502Means for blocking the piston or the fluid passageway to prevent illegal refilling of a syringe for blocking the piston
    • A61M2005/5033Means for blocking the piston or the fluid passageway to prevent illegal refilling of a syringe for blocking the piston by use of an intermediate blocking member positioned between the syringe barrel and the piston rod to prevent retraction of the latter, e.g. toothed clip placed on the piston rod
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/58Means for facilitating use, e.g. by people with impaired vision
    • A61M2205/581Means for facilitating use, e.g. by people with impaired vision by audible feedback
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/58Means for facilitating use, e.g. by people with impaired vision
    • A61M2205/583Means for facilitating use, e.g. by people with impaired vision by visual feedback
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2210/00Anatomical parts of the body
    • A61M2210/06Head
    • A61M2210/0612Eyes

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Anesthesiology (AREA)
  • Hematology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
TW110140312A 2020-10-30 2021-10-29 特別用於玻璃體內流體給藥的給藥裝置 TWI895534B (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP20205001.9 2020-10-30
EP20205001 2020-10-30

Publications (2)

Publication Number Publication Date
TW202233140A TW202233140A (zh) 2022-09-01
TWI895534B true TWI895534B (zh) 2025-09-01

Family

ID=73043100

Family Applications (1)

Application Number Title Priority Date Filing Date
TW110140312A TWI895534B (zh) 2020-10-30 2021-10-29 特別用於玻璃體內流體給藥的給藥裝置

Country Status (11)

Country Link
US (1) US20230390109A1 (https=)
EP (1) EP4237043B1 (https=)
JP (1) JP2023550281A (https=)
KR (1) KR20230098171A (https=)
CN (1) CN116583314A (https=)
AU (1) AU2021369609A1 (https=)
CA (1) CA3193701A1 (https=)
CL (1) CL2023001011A1 (https=)
MX (1) MX2023004995A (https=)
TW (1) TWI895534B (https=)
WO (1) WO2022090463A1 (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
USD866757S1 (en) * 2016-03-11 2019-11-12 Millennium Pharmaceuticals, Inc. Autoinjector
USD1037439S1 (en) 2022-01-17 2024-07-30 EyePoint Pharamaceuticals, Inc. Ocular injector
TW202539597A (zh) * 2023-11-08 2025-10-16 美商再生元醫藥公司 用於眼部組織之藥物遞送的系統及方法

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20130324965A1 (en) * 2010-07-02 2013-12-05 Carebay Holding Ltd., Company Preservative-Free Follicle Stimulating Hormone Solution Delivery Device
US20160220327A1 (en) * 2015-01-29 2016-08-04 Bryan Tapocik Mechanical pen with improvements for pen removably retaining singleuse capsule containing tooth whitening compounds, dental bonding compounds and adhesives and removably retaining disposable tooth whitening applicators, disposable dental bonding compound applicators and disposable adhesive applicators
TW201729853A (zh) * 2015-11-13 2017-09-01 卡貝歐洲有限公司 用於藥物輸送裝置的啟動機構和包含該啟動機構的藥物輸送裝置

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5536249A (en) * 1994-03-09 1996-07-16 Visionary Medical Products, Inc. Pen-type injector with a microprocessor and blood characteristic monitor
US20060069350A1 (en) 2004-09-30 2006-03-30 Buenger David R Medical syringe injector pen
CN102209567B (zh) * 2008-10-01 2013-10-23 Shl集团有限责任公司 锥形弹簧致动的药剂输送装置
US20100231102A1 (en) 2009-03-16 2010-09-16 Peter Block Stowable and releasably securable mobile structure
WO2012105898A1 (en) * 2011-02-03 2012-08-09 Shl Group Ab Medicament delivery device
CN104080498B (zh) * 2011-09-22 2016-08-24 艾伯维公司 自动注射装置
DE202013000688U1 (de) * 2012-07-03 2013-03-05 Novartis Ag Glas-Spritze
EP3151881B1 (en) * 2014-06-05 2018-08-22 Carebay Europe Ltd. Medicament delivery device with delivery finish signal delay
WO2017029032A1 (en) * 2015-08-19 2017-02-23 Carebay Europe Ltd Variable single dose medicament delivery device
EP3727508B1 (en) * 2017-12-22 2024-10-23 Sanofi A drug delivery device

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20130324965A1 (en) * 2010-07-02 2013-12-05 Carebay Holding Ltd., Company Preservative-Free Follicle Stimulating Hormone Solution Delivery Device
US20160220327A1 (en) * 2015-01-29 2016-08-04 Bryan Tapocik Mechanical pen with improvements for pen removably retaining singleuse capsule containing tooth whitening compounds, dental bonding compounds and adhesives and removably retaining disposable tooth whitening applicators, disposable dental bonding compound applicators and disposable adhesive applicators
TW201729853A (zh) * 2015-11-13 2017-09-01 卡貝歐洲有限公司 用於藥物輸送裝置的啟動機構和包含該啟動機構的藥物輸送裝置

Also Published As

Publication number Publication date
CN116583314A (zh) 2023-08-11
WO2022090463A1 (en) 2022-05-05
CA3193701A1 (en) 2022-05-05
KR20230098171A (ko) 2023-07-03
MX2023004995A (es) 2023-05-12
US20230390109A1 (en) 2023-12-07
AU2021369609A1 (en) 2023-06-15
EP4237043A1 (en) 2023-09-06
EP4237043B1 (en) 2026-02-11
CL2023001011A1 (es) 2023-12-01
TW202233140A (zh) 2022-09-01
JP2023550281A (ja) 2023-12-01

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