TWI851106B - Thermal imaging endoscope system, endoscope catheter, detecting method for abnormal regions, device for displaying abnormal regions, and thermal imaging processing host thereof - Google Patents

Thermal imaging endoscope system, endoscope catheter, detecting method for abnormal regions, device for displaying abnormal regions, and thermal imaging processing host thereof Download PDF

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TWI851106B
TWI851106B TW112111006A TW112111006A TWI851106B TW I851106 B TWI851106 B TW I851106B TW 112111006 A TW112111006 A TW 112111006A TW 112111006 A TW112111006 A TW 112111006A TW I851106 B TWI851106 B TW I851106B
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thermal
abnormal
area
sensing points
thermal sensing
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TW112111006A
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TW202327522A (en
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林志儒
劉怡緯
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晶鑠科技有限公司
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Abstract

A thermal imaging endoscope system comprises a thermal imaging endoscope catheter and a control device. The thermal imaging endoscope catheter includes a tube body, a thermal imaging capturing component, an ablation component and a towing component. The thermal imaging capturing component and an end of the ablation component are located at the head of the tube body. The thermal imaging capturing component captures thermal images from an imaging region and converts the thermal images into image signals. The towing component is located within the tube body and connected to the head. The control device includes a receiving component, a driving component, an optical waveguide and a controller. The driving component connects to the towing component. The optical waveguide includes a light pipe and a gate. The controller actuates the driving component based on the ablated command received by the receiving component to drive the towing component towing the head, and to actuate the gate selectively, coupling or decoupling the light pipe to the ablation component. The controller receives and outputs image signals.

Description

熱影像內視鏡系統、其內視鏡導管、其異常區域判斷方法、其異常區域顯示裝置、及其熱影像處理主機Thermal imaging endoscope system, endoscope catheter, abnormal area determination method, abnormal area display device, and thermal imaging processing host

一種內視鏡系統,尤指一種可以擷取組織熱影像及/或選擇性對異常組織處置的內視鏡系統。 An endoscopic system, particularly one that can capture thermal images of tissue and/or selectively treat abnormal tissue.

內視鏡通常包含內視鏡導管和可見光光源,部份手術過程中的內視鏡會利用提供可見光光源照射於人體組織上,並以顯影劑為外來物質,透過細胞代謝差異的方法產生組織螢光差異來協助辨識人體內異常組織。隨著技術的進步,部分內視鏡開始配合腫瘤消融裝置,需使用者自行操作控制消融裝置的位置以對準異常組織進行消融。 An endoscope usually includes an endoscope catheter and a visible light source. In some surgical procedures, the endoscope will provide a visible light source to illuminate human tissues, and use a contrast agent as a foreign substance to produce tissue fluorescence differences through differences in cell metabolism to help identify abnormal tissues in the human body. With the advancement of technology, some endoscopes have begun to cooperate with tumor ablation devices, requiring users to operate and control the position of the ablation device to align the abnormal tissue for ablation.

本發明人在設計內視鏡系統時,欲避免顯影劑的使用而無形中增加人體組織之負擔,同時避免因組織未有明顯顏色變化而導致內視鏡無法於可見光視線波段偵測到異常組織的情況出現。同時發明人需確保可客觀準確瞄準異常組織及方便使用者對異常組織進行消融。 When designing the endoscope system, the inventor wanted to avoid the use of contrast agents and thus invisibly increase the burden on human tissues, and at the same time avoid the situation where the endoscope cannot detect abnormal tissues in the visible light band due to the lack of obvious color changes in the tissues. At the same time, the inventor needs to ensure that the abnormal tissues can be accurately targeted objectively and conveniently for users to ablate the abnormal tissues.

鑑於上述本發明人之需求,本發明提供一種熱影像內視鏡 系統,依據一實施例,熱影像內視鏡系統包含熱影像內視鏡導管和控制裝置。熱影像內視鏡導管包含管體、熱影像擷取組件、處置元件和連動元件。管體一端具有頭部。熱影像擷取組件位於頭部並用以自攝像區域擷取熱影像並將之轉換為影像訊號,影像訊號用以產生視覺影像,視覺影像包含多個熱感應點,且多個熱感應點具有一個平均溫度,相鄰的各熱感應點的溫度與平均溫度之差異大於預定溫差時視覺影像具有異常區域,且異常區域的尺寸小於或等於上限尺寸時,將異常區域內的熱感應點做為異常標示,上限尺寸為10毫米。熱影像擷取組件具有攝像區域。處置元件位於管體內且處置元件的一端位於頭部。處置元件具有處置區域,其位於該攝像區域內。連動元件位於管體內並連接頭部。控制裝置包含接收元件、驅動元件、導光組件和控制器。接收元件用以接收處置命令。驅動元件連接連動元件。導光組件包含導光件和閘門。導光件包含輸入端和輸出端。閘門被致動以選擇性地將導光件之輸出端耦合與不耦合於處置元件。控制器用以接收並輸出影像訊號。控制器依據處置命令致動驅動元件以使連動元件連動頭部作動、和致動閘門。 In view of the above-mentioned needs of the inventor, the present invention provides a thermal imaging endoscope system. According to one embodiment, the thermal imaging endoscope system includes a thermal imaging endoscope conduit and a control device. The thermal imaging endoscope conduit includes a tube body, a thermal image capture component, a processing element and a linkage element. One end of the tube body has a head. The thermal image capture component is located on the head and is used to capture thermal images from the imaging area and convert them into image signals. The image signals are used to generate visual images. The visual images include multiple thermal sensing points, and the multiple thermal sensing points have an average temperature. When the difference between the temperature of each adjacent thermal sensing point and the average temperature is greater than a predetermined temperature difference, the visual image has an abnormal area, and when the size of the abnormal area is less than or equal to the upper limit size, the thermal sensing points in the abnormal area are marked as abnormal, and the upper limit size is 10 mm. The thermal image capturing component has a camera area. The treatment element is located within the body of the tube and one end of the treatment element is located at the head. The treatment element has a treatment area located within the imaging area. The linkage element is located in the body of the tube and connected to the head. The control device includes a receiving element, a driving element, a light guide assembly and a controller. The receiving element is used to receive a processing command. The driving element is connected to the linking element. The light guide assembly includes a light guide and a gate. The light guide includes an input end and an output end. The gate is actuated to selectively couple and uncouple the output end of the light guide to the processing element. The controller is used to receive and output an image signal. The controller actuates the driving element according to the processing command to cause the linking element to link the head and actuate the gate.

在一些實施例中,熱影像內視鏡系統包含主機。主機包含顯示器、輸入元件和處理器。輸入元件用以接收輸入訊號。處理器依據影像訊號,使顯示器顯示視覺影像。處理器依據輸入訊號而輸出處置命令。 In some embodiments, the thermal imaging endoscope system includes a host. The host includes a display, an input element, and a processor. The input element is used to receive an input signal. The processor enables the display to display a visual image based on the image signal. The processor outputs a processing command based on the input signal.

在一些實施例中,熱影像內視鏡系統包含雷射裝置。雷射裝置包含出光管。出光管耦合於導光件之輸入端。雷射裝置被致動時,於出光管發出雷射光。 In some embodiments, the thermal imaging endoscope system includes a laser device. The laser device includes a light emitting tube. The light emitting tube is coupled to the input end of the light guide. When the laser device is activated, laser light is emitted from the light emitting tube.

本發明另提供一種熱影像內視鏡導管,依據一實施例,熱影像內視鏡導管包含管體、熱影像擷取組件、處置元件和連動元件。管體一端具有頭部,管體之另一端具有連接部。熱影像擷取組件位於頭部並用以自攝像區域擷取熱影像並將之轉換為影像訊號自該連接部輸出,影像訊號用以產生視覺影像,視覺影像包含多個熱感應點,且多個熱感應點具有一個平均溫度,相鄰的各熱感應點的溫度與平均溫度之差異大於預定溫差時視覺影像具有異常區域,且異常區域的尺寸小於或等於上限尺寸時,將異常區域內的熱感應點做為異常標示,上限尺寸為10毫米。處置元件包含處置頭和光纖,光纖位於管體內且處置頭位於頭部。光纖一端位於連接部,光纖的另一端耦合於處置頭。處置元件具有處置區域,其位於攝像區域內。連動元件位於管體內並連接頭部。連動元件被致動時,連動管體的頭部作動。 The present invention further provides a thermal imaging endoscope catheter. According to one embodiment, the thermal imaging endoscope catheter comprises a tube body, a thermal image capturing assembly, a processing element and a linkage element. One end of the tube body has a head portion, and the other end of the tube body has a connecting portion. The thermal image capture component is located on the head and is used to capture thermal images from the imaging area and convert them into image signals for output from the connection part. The image signals are used to generate visual images. The visual images include multiple thermal sensing points, and the multiple thermal sensing points have an average temperature. When the difference between the temperature of each adjacent thermal sensing point and the average temperature is greater than the predetermined temperature difference, the visual image has an abnormal area, and when the size of the abnormal area is less than or equal to the upper limit size, the thermal sensing points in the abnormal area are marked as abnormal, and the upper limit size is 10 mm. The treatment element includes a treatment head and an optical fiber. The optical fiber is located in the tube body and the treatment head is located at the head. One end of the optical fiber is located at the connection part, and the other end of the optical fiber is coupled to the treatment head. The processing element has a processing area, which is located in the photographic area. The linkage element is located in the tube body and connected to the head. When the linkage element is actuated, the head of the linkage tube body moves.

本發明另提供一種熱影像異常區域判斷方法,依據一實施例,熱影像異常區域判斷方法包含接收視覺影像。視覺影像包含二維排列之多個熱感應點,每一熱感應點具有溫度。依據溫度獲得平均溫度。判斷相鄰的熱感應點之溫度與平均溫度的差異是否分別高出預定溫差,若是,則將相鄰的熱感應點做為異常區域,異常區域的尺寸小於或等於上限尺寸時,將異常區域內的熱感應點做為異常標示,上限尺寸為10毫米。 The present invention also provides a method for determining abnormal areas in thermal images. According to one embodiment, the method for determining abnormal areas in thermal images includes receiving visual images. The visual image includes multiple thermal sensing points arranged in a two-dimensional manner, and each thermal sensing point has a temperature. Get the average temperature based on the temperature. Determine whether the difference between the temperature of the adjacent thermal sensing points and the average temperature is higher than the predetermined temperature difference. If so, the adjacent thermal sensing points are regarded as abnormal areas. When the size of the abnormal area is less than or equal to the upper limit size, the abnormal area is The thermal sensing point inside is used as an abnormality mark, and the upper limit size is 10 mm.

本發明另提供一種熱影像異常區域顯示裝置,依據一些實施例,熱影像異常區域顯示裝置包含接收模組、處理模組和顯示模組。接收模組用以接收視覺影像,視覺影像包含二維排列之多個熱感應點, 每熱感應點具有溫度。處理模組用以依據溫度獲得平均溫度,判斷相鄰的熱感應點之溫度與平均溫差的差異是否分別高出預定溫差,若是,則將相鄰的熱感應點做為異常區域,異常區域的尺寸小於或等於上限尺寸時,將異常區域內的熱感應點做為異常標示,上限尺寸為10毫米。顯示模組用以顯示視覺影像、異常區域及異常標示。 The present invention also provides a thermal image abnormal area display device. According to some embodiments, the thermal image abnormal area display device includes a receiving module, a processing module and a display module. The receiving module is used to receive visual images. The visual images include multiple thermal sensing points arranged in a two-dimensional manner, and each thermal sensing point has a temperature. The processing module is used to obtain the average temperature based on the temperature, and determine whether the difference between the temperature of the adjacent thermal sensing points and the average temperature difference is higher than the predetermined temperature difference. If so, the adjacent thermal sensing points are regarded as abnormal areas, and the abnormal area When the size is less than or equal to the upper limit size, the thermal sensing point in the abnormal area is used as an abnormality mark, and the upper limit size is 10 mm. The display module is used to display visual images, abnormal areas and abnormal signs.

本發明另提供一種熱影像處理主機,依據一些實施例,熱影像處理主機包含顯示器和處理器。處理器用以接收影像訊號,其對應視覺影像,視覺影像包含二維排列之多個熱感應點,每熱感應點具有溫度。依據溫度獲得平均溫度。判斷相鄰的熱感應點之溫度與平均溫度之差異是否分別高出預定溫差,若是,則將相鄰的熱感應點做為異常區域,異常區域的尺寸小於或等於上限尺寸時,將異常區域內的熱感應點做為異常標示,上限尺寸為10毫米。控制顯示器顯示熱視覺影像、異常區域和異常標示。 The present invention also provides a thermal image processing host. According to some embodiments, the thermal image processing host includes a display and a processor. The processor is used to receive an image signal, which corresponds to a visual image. The visual image includes a plurality of thermal sensing points arranged in a two-dimensional manner, and each thermal sensing point has a temperature. Get the average temperature based on the temperature. Determine whether the difference between the temperature of the adjacent thermal sensing points and the average temperature is higher than the predetermined temperature difference. If so, the adjacent thermal sensing points are regarded as abnormal areas. When the size of the abnormal area is less than or equal to the upper limit size, the abnormal area is The thermal sensing point inside is used as an abnormality mark, and the upper limit size is 10 mm. The control display displays thermal vision images, abnormal areas and abnormal signs.

以下在實施方式中詳細敘述本發明之詳細特徵以及優點,其內容足以使任何熟習相關技藝者瞭解本發明之技術內容並據以實施,且根據本說明書所揭露之內容、申請專利範圍及圖式,任何熟習相關技藝者可輕易地理解本發明相關之目的及優點。 The detailed features and advantages of the present invention are described in detail in the following implementation method. The content is sufficient for anyone familiar with the relevant technology to understand the technical content of the present invention and implement it accordingly. According to the content disclosed in this specification, the scope of the patent application and the drawings, anyone familiar with the relevant technology can easily understand the relevant purposes and advantages of the present invention.

10:熱影像內視鏡導管 10: Thermal imaging endoscope catheter

12:管體 12: Tube body

120:頭部 120: Head

122:連接部 122: Connection part

13:金屬套環 13:Metal ferrule

14:熱影像擷取組件 14: Thermal image acquisition component

16:處置元件 16: Processing element

160:處置頭 160: Disposal Head

162:光纖 162: Optical fiber

18:連動元件 18: Linking components

20:控制裝置 20: Control device

22:接收元件 22: Receiving element

24:驅動元件 24: Driving components

26:導光組件 26: Light guide assembly

260:導光件 260: Light guide

262:輸入端 262: Input port

264:輸出端 264: Output port

266:閘門 266: Gate

27:遙桿 27: Remote control

28:控制器 28: Controller

30:主機 30: Host

32:顯示器 32: Display

34:輸入元件 34: Input components

36:處理器 36: Processor

40:雷射裝置 40: Laser device

400:出光管 400: light pipe

50:熱影像異常區域顯示裝置 50: Thermal imaging abnormal area display device

500:接收模組 500: receiving module

520:處理模組 520: Processing module

540:顯示模組 540: Display module

60:熱影像處理主機 60: Thermal image processing host

600:顯示器 600: Display

620:處理器 620: Processor

A,A34,A43,A44,A45,A54:熱感應點 A, A 34 , A 43 , A 44 , A 45 , A 54 : Heat sensing point

D1:預定距離 D1: Predetermined distance

R1:攝像區域 R1: Photography area

R2:處置區域 R2: Disposal area

R3,R4:異常區域 R3, R4: Abnormal area

P1:中央位置 P1: Central location

P2:處置位置 P2: Disposal position

P3:異常區域 P3: Abnormal area

S10~S14,S140~S144,S20~S24,S80~S82:步驟 S10~S14,S140~S144,S20~S24,S80~S82: Steps

圖1係為依據一些實施例之熱影像內視鏡系統之立體示意圖。 FIG1 is a three-dimensional schematic diagram of a thermal imaging endoscope system according to some embodiments.

圖2係為依據一些實施例之熱影像內視鏡系統之控制裝置結構示意圖。 FIG2 is a schematic diagram of the control device structure of a thermal imaging endoscope system according to some embodiments.

圖3係為依據一些實施例之熱影像內視鏡導管之局部截面示意圖。 FIG3 is a partial cross-sectional schematic diagram of a thermal imaging endoscope catheter according to some embodiments.

圖4係依據一些實施例之熱影像內視鏡導管之頭部端面示意圖。 FIG4 is a schematic diagram of the end face of the head of a thermal imaging endoscope catheter according to some embodiments.

圖5係依據一些實施例之頭部及攝像區域與處置區域之示意圖。 FIG5 is a schematic diagram of the head, the imaging area, and the processing area according to some embodiments.

圖6係依據一些實施例之視覺影像之示意圖。 FIG6 is a schematic diagram of visual images according to some embodiments.

圖7A係為依據一些實施例之視覺影像之異常標示程序之流程示意圖。 FIG. 7A is a flow chart of an abnormality marking process for visual images according to some embodiments.

圖7B係為依據一些實施例之視覺影像示意圖(一),顯示異常標示程序。 FIG. 7B is a visual image schematic diagram (I) showing the abnormality marking process according to some embodiments.

圖7C係為依據一些實施例之視覺影像示意圖(二),顯示異常標示程序。 FIG. 7C is a schematic diagram of a visual image according to some embodiments (II), showing the abnormality marking process.

圖7D係為依據一些實施例之視覺影像示意圖(三),顯示異常標示程序。 FIG. 7D is a schematic diagram of a visual image according to some embodiments (III), showing the abnormality marking process.

圖8係為依據一些實施例之熱影像異常區域判斷方法之流程圖。 FIG8 is a flow chart of a method for determining abnormal areas of thermal images according to some embodiments.

圖9係為依據一些實施例之熱影像異常區域顯示裝置之功能方塊圖。 FIG. 9 is a functional block diagram of a thermal image abnormal area display device according to some embodiments.

圖10係為依據一些實施例之熱影像處理主機之功能方塊圖。 FIG. 10 is a functional block diagram of a thermal image processing host according to some embodiments.

圖11係為依據一些實施例之熱影像處理主機之處理器的異常區域判斷步驟。 FIG. 11 shows the abnormal area determination steps of the processor of the thermal image processing host according to some embodiments.

請參考圖1及圖3,圖1為依據一些實施例之熱影像內視鏡系統之立體示意圖,圖3係為依據一些實施例之熱影像內視鏡導管之局部截面示意圖。熱影像內視鏡系統包含熱影像內視鏡導管10及控制裝置20。使用者使用時,可將熱影像內視鏡導管10的一端置入人體內,透過控制 裝置20的控制,可控制熱影像內視鏡導管10的熱影像擷取組件14的攝像區域在人體內的位置。在一些實施例中,熱影像內視鏡系統另包含一主機30,主機30包含顯示器32,顯示器32將熱影像擷取組件14從攝像區域所擷取到的影像訊號顯示為視覺影像,供使用者檢視。在一些實施例中,熱影像內視鏡系統另包含一雷射裝置40。雷射裝置40被致動時用以發出雷射光。當使用者觀察視覺影像中有異常組織時,可驅動雷射裝置40發出雷射光,經過熱影像內視鏡導管10的處置元件16而消融該異常組織。 Please refer to FIG. 1 and FIG. 3. FIG. 1 is a three-dimensional schematic diagram of a thermal imaging endoscope system according to some embodiments, and FIG. 3 is a partial cross-sectional schematic diagram of a thermal imaging endoscope catheter according to some embodiments. The thermal imaging endoscope system includes a thermal imaging endoscope catheter 10 and a control device 20. When the user uses it, one end of the thermal imaging endoscope catheter 10 can be inserted into the human body, and the position of the imaging area of the thermal imaging capture component 14 of the thermal imaging endoscope catheter 10 in the human body can be controlled by the control of the control device 20. In some embodiments, the thermal imaging endoscope system further includes a host 30, and the host 30 includes a display 32. The display 32 displays the image signal captured by the thermal imaging capture component 14 from the imaging area as a visual image for the user to view. In some embodiments, the thermal imaging endoscope system further includes a laser device 40. The laser device 40 is used to emit laser light when activated. When the user observes abnormal tissue in the visual image, the laser device 40 can be driven to emit laser light, which passes through the treatment element 16 of the thermal imaging endoscope catheter 10 to ablate the abnormal tissue.

請參考圖1至圖5,圖2係為依據一些實施例之熱影像內視鏡系統之控制裝置結構示意圖,圖4係依據一些實施例之熱影像內視鏡導管之頭部端面示意圖,圖5係依據一些實施之頭部及攝像區域與處置區域之示意圖。熱影像內視鏡系統包含熱影像內視鏡導管10及控制裝置20。熱影像內視鏡導管10包含管體12、熱影像擷取組件14、處置元件16及連動元件18。管體12一端具有頭部120(見於圖1)。熱影像擷取組件14位於管體12的頭部120。當頭部120進入人體體內進行熱影像拍攝時,熱影像擷取組件14自一攝像區域R1(見於圖5)擷取熱影像,並將之轉換為影像訊號。處置元件16位於管體12內,且處置元件16(見於圖3)的一端位於頭部120。處置元件16具有處置區域R2(見於圖5),處置區域R2位於攝像區域R1內,如圖5所示。連動元件18位於管體12內並連接頭部120,如圖3及圖4所示。控制裝置20包含接收元件22、驅動元件24、導光組件26及控制器28。接收元件22用以接收來自主機30的處置命令(容後詳述)。驅動元件24連接連動元件18。導光組件26包含導光件260及 閘門266,導光件260包含輸入端262及輸出端264。輸入端262可接收來自於雷射裝置40的光源,而輸出端264與處置元件16對接。閘門266被致動以選擇性地將導光件260之輸出端264光耦合或不耦合於處置元件16。舉例而言,閘門266為開啟狀態時,雷射光源可由導光件260經輸出端264耦合至處置元件16。閘門266為關閉狀態時,光源則被閘門266阻擋於導光件260處,而不會到達處置元件16。閘門266處可另增加光學連接器以達到光耦合的效果。控制器28依據處置命令致動驅動元件24以使連動元件18連動頭部120作動、以及致動閘門266。 Please refer to Figures 1 to 5. Figure 2 is a schematic diagram of the control device structure of the thermal imaging endoscope system according to some embodiments, Figure 4 is a schematic diagram of the head end face of the thermal imaging endoscope tube according to some embodiments, and Figure 5 is a schematic diagram of the head and the imaging area and the processing area according to some embodiments. The thermal imaging endoscope system includes a thermal imaging endoscope tube 10 and a control device 20. The thermal imaging endoscope tube 10 includes a tube body 12, a thermal image capture component 14, a processing element 16 and a linkage element 18. One end of the tube body 12 has a head 120 (see Figure 1). The thermal image capture component 14 is located at the head 120 of the tube body 12. When the head 120 enters the human body to take thermal images, the thermal image capture component 14 captures thermal images from an imaging area R1 (see FIG. 5 ) and converts them into image signals. The processing element 16 is located in the tube 12, and one end of the processing element 16 (see FIG. 3 ) is located at the head 120. The processing element 16 has a processing area R2 (see FIG. 5 ), and the processing area R2 is located in the imaging area R1, as shown in FIG. 5 . The linkage element 18 is located in the tube 12 and connected to the head 120, as shown in FIG. 3 and FIG. 4 . The control device 20 includes a receiving element 22, a driving element 24, a light guide component 26 and a controller 28. The receiving element 22 is used to receive a processing command from the host 30 (described in detail later). The driving element 24 is connected to the linking element 18. The light guide assembly 26 includes a light guide 260 and a gate 266. The light guide 260 includes an input end 262 and an output end 264. The input end 262 can receive a light source from the laser device 40, and the output end 264 is connected to the processing element 16. The gate 266 is actuated to selectively couple or uncouple the output end 264 of the light guide 260 to the processing element 16. For example, when the gate 266 is in an open state, the laser light source can be coupled to the processing element 16 from the light guide 260 through the output end 264. When the gate 266 is in a closed state, the light source is blocked by the gate 266 at the light guide 260 and does not reach the processing element 16. An optical connector can be added to the gate 266 to achieve the effect of optical coupling. The controller 28 actuates the driving element 24 according to the processing command to make the linkage element 18 and the head 120 move, and actuate the gate 266.

因此,當使用者將熱影像內視鏡導管10的頭部120置入人體內,可透過控制裝置20之控制,經驅動元件24連動連動元件18,而調整頭部120的角度,進而調整熱影像擷取組件14的攝像區域R1所在位置(容後說明)。 Therefore, when the user inserts the head 120 of the thermal imaging endoscope catheter 10 into the human body, the angle of the head 120 can be adjusted by controlling the control device 20 and linking the linking element 18 via the driving element 24, thereby adjusting the position of the imaging area R1 of the thermal imaging capture component 14 (to be explained later).

在一些實施例中,管體12一端具有頭部120,另一端具有一連接部122。連接部122連接於控制裝置20。連接部122連接於控制裝置20時,用以將熱影像擷取組件14電性連接至控制裝置、將連動元件18連接至驅動元件24、及將處置元件16與導光件260對接。連接部122可以是一般常見的連接器或特製的連接器。 In some embodiments, the tube 12 has a head 120 at one end and a connecting portion 122 at the other end. The connecting portion 122 is connected to the control device 20. When the connecting portion 122 is connected to the control device 20, it is used to electrically connect the thermal image capture component 14 to the control device, connect the connecting element 18 to the driving element 24, and connect the processing element 16 to the light guide 260. The connecting portion 122 can be a common connector or a specially made connector.

請參考圖3,在一些實施例中,熱影像內視鏡導管10包含一金屬套環13。金屬套環13位於管體12的頭部120並用以固定熱影像擷取組件14及處置元件16的一端,而使熱影像擷取組件14和處置元件16在管體12的頭部120處維持固定的相對位置。由於可採用不同型號、焦距、視角大小的熱影像擷取組件14,以及採用不同大小、處置深度的處置元件 16,故並未限定熱影像擷取組件14和處置元件16的相對位置必然為多少距離,而係以熱影像擷取組件14的鏡頭直徑、處置元件16一端之大小、及管體12的直徑(粗度)訂定。舉例而言,若採用的熱影像擷取組件14的鏡頭直徑為5毫米(mm),位於頭部120一端的處置元件16的直徑大小為1.8毫米,管體12橫截面的直徑大小為10毫米,則熱影像擷取組件14與處置元件16的相對位置(即熱影像擷取組件14之鏡頭的中心位置與處置元件16中心位置的距離)可以是3.6毫米。熱影像擷取組件14和處置元件16維持固定的相對位置係為便於計算驅動元件24轉動角度的計算。 Referring to FIG. 3 , in some embodiments, the thermal imaging endoscope catheter 10 includes a metal collar 13. The metal collar 13 is located at the head 120 of the tube body 12 and is used to fix the thermal imaging capture assembly 14 and one end of the treatment element 16, so that the thermal imaging capture assembly 14 and the treatment element 16 maintain a fixed relative position at the head 120 of the tube body 12. Since thermal imaging capture assemblies 14 of different models, focal lengths, and viewing angles can be used, and treatment elements 16 of different sizes and treatment depths can be used, the relative position of the thermal imaging capture assembly 14 and the treatment element 16 is not limited to a certain distance, but is determined by the lens diameter of the thermal imaging capture assembly 14, the size of one end of the treatment element 16, and the diameter (thickness) of the tube body 12. For example, if the lens diameter of the thermal image capture component 14 is 5 mm, the diameter of the treatment element 16 at one end of the head 120 is 1.8 mm, and the diameter of the cross section of the tube 12 is 10 mm, then the relative position of the thermal image capture component 14 and the treatment element 16 (i.e., the distance between the center position of the lens of the thermal image capture component 14 and the center position of the treatment element 16) can be 3.6 mm. The thermal image capture component 14 and the treatment element 16 maintain a fixed relative position to facilitate the calculation of the rotation angle of the driving element 24.

請續參考圖5,熱影像擷取組件14的攝像區域R1為熱影像擷取組件14的焦距區域,意即,在該焦距區域所擷取到的熱影像較為清晰。類似的,處置元件16的處置區域R2是指處置元件16在對組織進行處理時的聚焦區域(例如用以處置組織的雷射光的聚焦區域)。攝像區域R1與處置區域R2間具有一預定距離D1,此預定距離D1可為但不限於攝像區域R1的中心點至處置區域R2的中心點的距離。該預定距離D1之用途,容後說明。 Please continue to refer to Figure 5. The imaging area R1 of the thermal image capturing component 14 is the focal area of the thermal image capturing component 14, which means that the thermal image captured in the focal area is clearer. Similarly, the processing area R2 of the processing element 16 refers to the focal area of the processing element 16 when processing the tissue (for example, the focal area of the laser light used to process the tissue). There is a predetermined distance D1 between the imaging area R1 and the processing area R2. This predetermined distance D1 can be but is not limited to the distance from the center point of the imaging area R1 to the center point of the processing area R2. The purpose of the predetermined distance D1 will be explained later.

請再參考圖2及圖3,在一些實施例中,熱影像內視鏡導管10包含多個連動元件18,例如但不限於圖2實施例的4個連動元件18。連動元件18可為牽引線,其材質可以採用記憶金屬之材質。連動元件18的一端連接於驅動元件24,另一端連接於熱影像內視鏡導管10的管體12的頭部120,從圖4中可以看出,該四個連動元件18連接在該頭部120的四分點的位置(即每個相距約90度)。在圖2、圖3及圖4的實施例中,驅動元件24以雙軸馬達為例,連動元件18以四條牽引線為例。雙軸馬達可包 含X軸及Y軸。二條連動元件18的一端分別連接雙軸馬達的X軸,另一端連接圖4位於頭部120之90度及270度位置。另二條連動元件18的一端分別連接雙軸馬達的Y軸,另一端連接圖4位於頭部120之0度及180度位置。雙軸馬達分別控制X軸及/或Y軸的轉速及/或旋轉角度。因此,當驅動元件24的X軸被驅動以牽引圖4位於90度及270度位置的二條連動元件18時,頭部120將朝圖4的+X或-X方向擺動;類似的,當驅動元件24被驅動以牽引圖4位於0度及180度位置的二條連動元件18時,頭部120將朝圖4的+Y或-Y方向擺動。因此,控制器28可以依據處置命令而使頭部120朝+X、-X、+Y、及/或-Y方向轉動。在一些實施例中,驅動元件24為但不限於雙軸馬達、伺服馬達或步進馬達。 Please refer to FIG. 2 and FIG. 3 again. In some embodiments, the thermal imaging endoscope catheter 10 includes a plurality of linkage elements 18, such as but not limited to the four linkage elements 18 in the embodiment of FIG. 2. The linkage element 18 may be a lead wire, and its material may be a memory metal material. One end of the linkage element 18 is connected to the driving element 24, and the other end is connected to the head 120 of the tube body 12 of the thermal imaging endoscope catheter 10. As can be seen from FIG. 4, the four linkage elements 18 are connected at the positions of the four points of the head 120 (i.e., each is about 90 degrees apart). In the embodiments of FIG. 2, FIG. 3 and FIG. 4, the driving element 24 is exemplified by a double-axis motor, and the linkage element 18 is exemplified by four lead wires. The double-axis motor may include an X-axis and a Y-axis. One end of two linkage elements 18 is connected to the X axis of the double-axis motor, and the other end is connected to the 90 degree and 270 degree positions of the head 120 in FIG. 4. One end of the other two linkage elements 18 is connected to the Y axis of the double-axis motor, and the other end is connected to the 0 degree and 180 degree positions of the head 120 in FIG. 4. The double-axis motor controls the rotation speed and/or rotation angle of the X axis and/or Y axis respectively. Therefore, when the X axis of the driving element 24 is driven to pull the two linking elements 18 at 90 degrees and 270 degrees in FIG. 4, the head 120 will swing toward the +X or -X direction of FIG. 4; similarly, when the driving element 24 is driven to pull the two linking elements 18 at 0 degrees and 180 degrees in FIG. 4, the head 120 will swing toward the +Y or -Y direction of FIG. 4. Therefore, the controller 28 can rotate the head 120 toward the +X, -X, +Y, and/or -Y direction according to the processing command. In some embodiments, the driving element 24 is but not limited to a dual-axis motor, a servo motor, or a stepper motor.

請參考圖1,在一些實施例中,控制裝置20包含遙桿27,遙桿27可以由使用者控制,以控制熱影像內視鏡導管10的頭部120的轉動角度,該遙桿27可以是提供二維輸入之遙桿。遙桿27耦接於控制器28,使用者藉由遙桿27輸入方向指令後,由遙桿27將對應訊號傳送給控制器28,控制器28據以控制驅動元件24使連動元件18連動頭部120。 Please refer to FIG. 1 . In some embodiments, the control device 20 includes a remote control 27 . The remote control 27 can be controlled by a user to control the rotation angle of the head 120 of the thermal imaging endoscope catheter 10 . The remote control 27 can be a remote control that provides two-dimensional input. The remote control 27 is coupled to the controller 28 . After the user inputs a direction command through the remote control 27 , the remote control 27 transmits a corresponding signal to the controller 28 . The controller 28 controls the driving element 24 accordingly so that the linkage element 18 links the head 120 .

上述實施例中,熱影像擷取組件14可用以偵測人體熱輻射,例如紅外線顯像元件。紅外線顯像元件可偵測之波段為7.5~14微米(μm),而人體所散發的紅外輻射波段介於8~12微米之間。人體之異常組織與正常組織之間具有代謝及行為表徵的差異,致使異常組織產生區域性的溫度差異。故可透過熱影像擷取組件14取得人體組織的溫度,進而判斷是否有異常組織存在。除紅外線顯像元件以外,其他接收波段可涵蓋熱體輻射熱範圍之熱影像元件皆可達到此功效,因以人體本身之熱 輻射作為熱影像擷取組件14的偵測對象,故不需使用任何顯影劑增加身體之負擔。熱影像擷取組件14之選擇以體積越小但視野越大的為主。另,可根據使用者的需求搭載可輸出不同空間解析度之影像的熱影像擷取組件14。空間解析度係影響異常組織影像之清晰度。於偵測人體中的異常組織時,較大的空間解析度可使熱影像內視鏡系統辨識出更小的異常組織以及更精確的取得該異常組織尺寸。例如使用空間解析度為10~20微米之熱影像擷取組件14時,可觀察到癌細胞尺度大小的精讀,進而達到可偵測癌細胞等異常組織的效果。熱影像內視鏡系統可應用於人體腹腔、上下消化道檢測,可於腹腔手術中直接導入腹腔進行影像協助,亦可於上下消化道檢測使用,以及術後檢測使用。 In the above embodiment, the thermal image acquisition component 14 can be used to detect human thermal radiation, such as an infrared imaging element. The infrared imaging element can detect a wavelength of 7.5 to 14 micrometers (μm), while the infrared radiation emitted by the human body is between 8 and 12 micrometers. There are differences in metabolism and behavioral characteristics between abnormal tissues and normal tissues in the human body, resulting in regional temperature differences in abnormal tissues. Therefore, the temperature of human tissues can be obtained through the thermal image acquisition component 14 to determine whether abnormal tissues exist. In addition to infrared imaging elements, other thermal imaging elements with receiving bands that can cover the range of heat radiation from heat bodies can achieve this effect. Since the thermal radiation of the human body is used as the detection object of the thermal imaging acquisition component 14, there is no need to use any developer to increase the burden on the body. The selection of thermal imaging acquisition components 14 is mainly based on the smaller volume but the larger field of view. In addition, thermal imaging acquisition components 14 that can output images with different spatial resolutions can be equipped according to the needs of users. Spatial resolution affects the clarity of abnormal tissue images. When detecting abnormal tissues in the human body, a larger spatial resolution allows the thermal imaging endoscope system to identify smaller abnormal tissues and obtain the size of the abnormal tissue more accurately. For example, when using a thermal image acquisition component 14 with a spatial resolution of 10 to 20 microns, the size of cancer cells can be observed accurately, thereby achieving the effect of detecting abnormal tissues such as cancer cells. The thermal imaging endoscope system can be applied to the human abdominal cavity and upper and lower digestive tract inspections. It can be directly introduced into the abdominal cavity for imaging assistance during abdominal surgery, and can also be used for upper and lower digestive tract inspections, as well as postoperative inspections.

在一些實施例中,熱影像內視鏡系統可包含主機30。主機30包含顯示器32、輸入元件34及處理器36。該輸入元件34用以接收一輸入訊號。處理器36依據該影像訊號,使該顯示器32顯示一視覺影像。該處理器36依據該輸入訊號而輸出該處置命令。在一些實施例中,主機30耦接該接收元件22,主機30例如但不限於透過USB連接線而耦接該接收元件22。熱影像擷取組件14自攝像區域R1擷取熱影像,並將之轉換為影像訊號,經由控制裝置20而傳送至處理器36。控制裝置20可以透過有線或無線方式傳輸該影像訊號給主機30。 In some embodiments, the thermal imaging endoscope system may include a host 30. The host 30 includes a display 32, an input element 34, and a processor 36. The input element 34 is used to receive an input signal. The processor 36 causes the display 32 to display a visual image according to the image signal. The processor 36 outputs the processing command according to the input signal. In some embodiments, the host 30 is coupled to the receiving element 22, and the host 30 is coupled to the receiving element 22 through a USB connection cable, for example but not limited to. The thermal image capture component 14 captures the thermal image from the imaging area R1 and converts it into an image signal, which is transmitted to the processor 36 via the control device 20. The control device 20 can transmit the image signal to the host 30 by wire or wirelessly.

處理器36依據該影像訊號而使顯示器32顯示一視覺影像。視覺影像例如但不限於如圖6所示之視覺影像。此視覺影像係為可使使用者直觀的辨識出是否具有異常組織。在一些實施例中,視覺影像將不同溫度的以不同色彩來顯示;亦可將異常組識以醒目的方式呈現,以達到 提供使用者直觀辨識異常區域的效果。以圖6實施例為例,圖6將正當溫度的組織以較淺的灰色呈現,而溫度異常的組織則以較暗的灰色呈現。視覺影像包含二維排列之多個熱感應點A,每一熱感應點A具有一溫度,該溫度對應區域組織之溫度。視覺影像對應熱影像擷取組件14的攝像區域R1,因此,視覺影像的每一熱感應點A即對應攝像區域R1的各組織點,每一該熱感應點A的溫度即為對應的各該組識點的溫度。處理器36亦可依據熱感應點A的數量及對應的各組織點面積得出異常區域的範圍大小,而視覺影像中對異常區域處標示該異常區域的範圍大小,如圖6中標示該較暗的灰色的區域大之大小為10毫米。 The processor 36 causes the display 32 to display a visual image according to the image signal. The visual image is, for example, but not limited to, the visual image shown in FIG6 . This visual image is used to allow the user to intuitively identify whether there is an abnormal tissue. In some embodiments, the visual image displays different temperatures in different colors; the abnormal tissue can also be presented in a striking manner to achieve the effect of providing the user with an intuitive identification of the abnormal area. Taking the embodiment of FIG6 as an example, FIG6 presents the tissue with a normal temperature in a lighter gray, and the tissue with an abnormal temperature in a darker gray. The visual image includes a plurality of thermal sensing points A arranged in two dimensions, each thermal sensing point A having a temperature, and the temperature corresponds to the temperature of the regional tissue. The visual image corresponds to the imaging area R1 of the thermal image acquisition component 14. Therefore, each thermal sensing point A of the visual image corresponds to each tissue point of the imaging area R1, and the temperature of each thermal sensing point A is the temperature of the corresponding tissue point. The processor 36 can also obtain the size of the abnormal area according to the number of thermal sensing points A and the area of the corresponding tissue points, and mark the size of the abnormal area in the visual image, such as the darker gray area marked in Figure 6 is 10 mm.

請復參考圖6,在一些實施例中,處理器36對影像訊號進行一異常標示程序,使顯示器32可選擇性的於視覺影像上顯示異常標示。其中,選擇性係指當熱影像擷取組件14所擷取的人體局部組織中,若處理器36判斷有符合異常區域時,致使顯示器32以一異常標示方式顯示該區域;若處理器36未偵測到異常區域,則不會標示任何異常標示於視覺影像中。視覺影像中之異常標示不限於一個,可同時顯示多個異常標示。 Please refer to Figure 6 again. In some embodiments, the processor 36 performs an abnormal marking process on the image signal so that the display 32 can selectively display the abnormal mark on the visual image. The selectivity means that when the processor 36 determines that there is an abnormal area in the local tissue of the human body captured by the thermal image capture component 14, the display 32 displays the area in an abnormal marking manner; if the processor 36 does not detect the abnormal area, no abnormal mark will be marked in the visual image. The abnormal mark in the visual image is not limited to one, and multiple abnormal marks can be displayed at the same time.

關於前述異常標示程序,請參考圖7A至圖7D,圖7A係為依據一些實施例之視覺影像之異常標示程序之流程示意圖。圖7B至圖7D分別為依據一些實施例之視覺影像示意圖(一)、(二)、及(三),顯示之異常標示程序。異常標示程序由控制器28執行,該異常標示程序包含:步驟S80:判斷是否存在一異常區域,該異常區域包含相鄰 該些熱感應點A且該些相鄰的熱感應點A之該些溫度與一平均溫度之差異大於一預定溫差;及步驟S82:響應該異常區域,判斷該異常區域是否小於或等於一上限尺寸,若是,則將該異常區域做為該異常標示。意即,當該異常區域存在且該異常區域的一尺寸小於或等於該上限尺寸時,將該異常區域內的該些熱感應點A做為該異常標示,該處理器36控制該顯示器32於該視覺影像上顯示該異常標示。 Regarding the aforementioned abnormality marking process, please refer to FIG. 7A to FIG. 7D. FIG. 7A is a flowchart of the abnormality marking process of visual images according to some embodiments. FIG. 7B to FIG. 7D are respectively schematic diagrams (1), (2), and (3) of visual images according to some embodiments, showing the abnormality marking process. The abnormal marking program is executed by the controller 28, and the abnormal marking program includes: step S80: judging whether there is an abnormal area, the abnormal area includes the adjacent thermal sensing points A and the difference between the temperatures of the adjacent thermal sensing points A and an average temperature is greater than a predetermined temperature difference; and step S82: responding to the abnormal area, judging whether the abnormal area is less than or equal to an upper limit size, if so, the abnormal area is used as the abnormal mark. That is, when the abnormal area exists and a size of the abnormal area is less than or equal to the upper limit size, the thermal sensing points A in the abnormal area are used as the abnormal mark, and the processor 36 controls the display 32 to display the abnormal mark on the visual image.

在一些實施例中,異常區域包含兩個或以上相鄰的熱感應點A,該些熱感應點A的溫度與周圍其他熱感應點A的溫度之差異大於該預定溫差。舉例而言,於圖7B中,熱感應點A44及熱感應點A45之溫度與周圍其他熱感應點A的溫度具有一溫度差異,此溫度差異大於該預定溫差,而此二熱感應點A44,A45為相鄰關係,故處理器36執行異常標示程序之步驟S80時判斷熱感應點A44及熱感應點A45為異常區域。類似的,請見於圖7C,熱感應點A34、A43、A44、A45及A54之溫度與周圍其他熱感應點A的溫度具有一溫度差異,此溫度差異大於該預定溫差,而此些熱感應點A34,A43,A44,A45,A54彼此相鄰,故處理器36執行異常標示程序之步驟S80時,將熱感應點A34,A43,A44,A45,A54判斷為異常區域。請另參考圖7D,雖然熱感應點A44之溫度與周圍其他之熱感應點A具有一溫度差異,且此差異大於該預定溫差,然熱感應點A44周圍並無其他具有大於預定溫差之熱感應點A,不符合「相鄰兩個或以上」之條件,故處理器36執行異常標示程序之步驟S80時,並不會將熱感應點A44判斷為異常區域。前述預定溫差可以為但不限於3℃。一般而言,相鄰的熱感應點A的溫度與 其他區域熱感應點A的平均溫度之溫度差異高於3℃,可以判斷該相鄰的熱感應點A其為異常組織。此異常組織可能是初期形成之腫瘤或離散之小腫瘤(溫度高於平均溫度3℃),也可能是魚骨等異物(溫度低於平均溫度3℃)。 In some embodiments, the abnormal area includes two or more adjacent thermal sensing points A, and the difference between the temperature of these thermal sensing points A and the temperature of other surrounding thermal sensing points A is greater than the predetermined temperature difference. For example, in FIG. 7B, the temperature of thermal sensing point A 44 and thermal sensing point A 45 has a temperature difference with the temperature of other surrounding thermal sensing points A, and this temperature difference is greater than the predetermined temperature difference. The two thermal sensing points A 44 and A 45 are adjacent to each other, so when the processor 36 executes step S80 of the abnormal marking procedure, it is determined that the thermal sensing point A 44 and the thermal sensing point A 45 are abnormal areas. Similarly, as shown in FIG. 7C , the temperatures of thermal sensing points A 34 , A 43 , A 44 , A 45 and A 54 have a temperature difference with the temperatures of other surrounding thermal sensing points A, and this temperature difference is greater than the predetermined temperature difference. These thermal sensing points A 34 , A 43 , A 44 , A 45 , A 54 are adjacent to each other, so when the processor 36 executes step S80 of the abnormal marking procedure, the thermal sensing points A 34 , A 43 , A 44 , A 45 , A 54 are determined as abnormal areas. Please refer to FIG. 7D . Although the temperature of the heat sensing point A 44 has a temperature difference with other surrounding heat sensing points A, and this difference is greater than the predetermined temperature difference, there are no other heat sensing points A with a temperature difference greater than the predetermined temperature difference around the heat sensing point A 44 , which does not meet the condition of "two or more adjacent". Therefore, when the processor 36 executes step S80 of the abnormal marking procedure, the heat sensing point A 44 will not be judged as an abnormal area. The aforementioned predetermined temperature difference can be, but is not limited to, 3°C. Generally speaking, if the temperature difference between the temperature of the adjacent heat sensing point A and the average temperature of the heat sensing points A in other areas is higher than 3°C, the adjacent heat sensing point A can be judged as an abnormal tissue. This abnormal tissue may be an early stage tumor or a small isolated tumor (temperature is 3°C higher than the average temperature), or it may be a foreign body such as fish bone (temperature is 3°C lower than the average temperature).

在一些實施例中,視覺影像將不同溫度以不同色彩顯示,圖7B中的熱感應點A44及熱感應點A45以灰色顯示,而其餘熱感應點A則以白色顯示,如此,使用者即可從視覺上判斷那些點的溫度異常。圖7C及圖7D亦同,不再贅述。在一些實施例中,處理器36執行步驟S80之判斷而獲得異常區域時,並不對該異常區域做顯目標示,僅於執行步驟S82後,才進行異常標示。 In some embodiments, the visual image displays different temperatures in different colors. The thermal sensing points A 44 and A 45 in FIG. 7B are displayed in gray, while the remaining thermal sensing points A are displayed in white. In this way, the user can visually determine which points have abnormal temperatures. The same is true for FIG. 7C and FIG. 7D, which will not be described in detail. In some embodiments, when the processor 36 executes the judgment of step S80 and obtains an abnormal area, the abnormal area is not marked. The abnormality is marked only after executing step S82.

在一些實施例中,步驟S82之上限尺寸可以是適合處置元件16處置的異常組織的尺寸,該上限尺寸是但不限於10毫米。當該異常區域存在且該異常區域的尺寸小於或等於該上限尺寸時,處理器36將異常區域內的該些熱感應點A做為異常標示,處理器36控制顯示器32於視覺影像上顯示該異常標示(如圖7B及圖7C的虛線框為異常區域R3及異常區域R4)。在一些實施例中,處理器36將視覺影像的每個熱感應點A依其溫度顯示,意即使用者能從各熱感應點A的顏色判斷溫度異常的熱感應點A,如圖7B、圖7C及圖7D所示。處理器36另將異常標示以虛線框標示,如圖7B及圖7C所示;而圖7D中的熱感應點A44僅為溫度異常的熱感應點A,並未有異常標示。 In some embodiments, the upper limit size of step S82 may be a size suitable for the abnormal tissue treated by the treatment element 16, and the upper limit size is but is not limited to 10 mm. When the abnormal area exists and the size of the abnormal area is less than or equal to the upper limit size, the processor 36 uses the thermal sensing points A in the abnormal area as abnormal markers, and the processor 36 controls the display 32 to display the abnormality on the visual image. Abnormality marks (the dotted boxes in Figure 7B and Figure 7C are abnormal areas R3 and R4). In some embodiments, the processor 36 displays each thermal sensing point A of the visual image according to its temperature, which means that the user can judge the thermal sensing point A with abnormal temperature from the color of each thermal sensing point A, as shown in FIG. 7B, As shown in FIG. 7C and FIG. 7D. The processor 36 also marks the abnormality with a dotted frame, as shown in FIG. 7B and FIG. 7C; and the thermal sensing point A 44 in FIG. 7D is only the thermal sensing point A with abnormal temperature, and No abnormality was noted.

前述適合處置元件16處置的異常組織尺寸與處置元件16及處置溫度有關,例如在選用Nd:YAG 1,064奈米(nm)波長之脈衝雷射 作為連接處置元件16之雷射光源,且處置溫度約為50℃時,在組織尺寸大於10毫米時,處置時間將過長且被處置的組織溫度會過高,因此,10毫米即做為該上限尺寸。 The size of the abnormal tissue suitable for treatment by the treatment element 16 is related to the treatment element 16 and the treatment temperature. For example, when a pulsed laser with a wavelength of 1,064 nanometers (nm) is selected as the laser light source connected to the treatment element 16 and the treatment temperature is about 50°C, when the tissue size is greater than 10 mm, the treatment time will be too long and the temperature of the treated tissue will be too high. Therefore, 10 mm is the upper limit size.

輸入元件34可用以接收來自使用者的輸入訊號。例如,當使用者從視覺影像中得知有異常標示且欲處置該異常標示所對應的異常組織時,使用者可藉由該輸入元件34發出對該異常組織進行處置的指令(輸入訊號)。前述輸入元件34例如但不限於鍵盤。處理器36依據該輸入訊號而輸出該處置命令。該控制器28經由該接收元件22接收該處置命令並依照處置命令移動頭部120及開啟閘門266等。處置命令可能包含移動指令、開啟或關閉閘門指令及/或照射時間長度指令。 The input element 34 can be used to receive input signals from the user. For example, when the user knows from the visual image that there is an abnormal mark and wants to treat the abnormal tissue corresponding to the abnormal mark, the user can issue an instruction (input signal) to treat the abnormal tissue through the input element 34. The aforementioned input element 34 is, for example but not limited to, a keyboard. The processor 36 outputs the treatment command according to the input signal. The controller 28 receives the treatment command through the receiving element 22 and moves the head 120 and opens the gate 266 according to the treatment command. The treatment command may include a movement command, a gate opening or closing command, and/or an irradiation time length command.

關於處置命令,請參考圖5及圖7B,在一些實施例中,圖7B的視覺影像對應圖5的攝像區域R1,其中,該視覺影像可以對應部分的該攝像區域R1,該視覺影像例如但不限於攝像區域R1中最大的矩形區域。該攝像區域R1的中心點對應視覺影像的中央位置P1,該處置區域R2對應視覺影像的處置位置P2。攝像區域R1與處置區域R2間的預定距離D1即對應中央位置P1與處置位置P2的距離。當該異常區域R3存在,且該輸入訊號為自動處置指令時,處理器36將依據中央位置P1、處置位置P2及異常標示產生一處置命令。處置命令包含移動參數及時間參數。移動參數可為頭部120之擺動角度,控制器28依據此移動參數致動驅動元件24,使連接驅動元件24的連動元件18牽引頭部120進行一定角度的調整(即頭部120沿如圖4中+X、-X、+Y、及/或-Y方向轉動),而將處置位置P2對準異常區域R3的一處(例如但不限於異常區域R3的左上角 P3),並由此處開始沿X或Y方向移動與掃描,直至處置位置P2行經整個異常區域R3。因攝像區域R1與處置區域R2間的預定距離D1即對應中央位置P1與處置位置P2的距離,處理器36可透過計算獲得處置元件16需移動多少距離及角度,方能使處置區域R2對準異常區域R3。時間參數為處理器36經計算後所得之異常組織需要消融的時間。時間參數之計算需參照異常區域的尺寸大小及雷射的功率參數。在一些實施列中,使用者可於輸入元件34輸入所使用的雷射之功率,主機30藉以計算出對應的時間參數。控制器28首先依據移動參數致動驅動元件24使頭部120作動,待處置區域R2對準異常區域R3後,致動閘門266使導光件260之輸出端264與處置元件16光耦合,此時由處置元件16輸出之雷射光可對異常區域R3的異常組織進行消融。於時間參數終了後,控制器28再致動閘門266關閉,以停止對異常區域R3的異常組織的消融動作。在此實施例中,雷射裝置40是採用人工啟動,意即,使用者在輸入自動處置指令時,先人工開啟雷射裝置40,使之發出雷射光。 Regarding the disposal command, please refer to FIG. 5 and FIG. 7B. In some embodiments, the visual image of FIG. 7B corresponds to the imaging area R1 of FIG. 5, wherein the visual image may correspond to a portion of the imaging area R1, such as but not limited to the largest rectangular area in the imaging area R1. The center point of the imaging area R1 corresponds to the central position P1 of the visual image, and the disposal area R2 corresponds to the disposal position P2 of the visual image. The predetermined distance D1 between the imaging area R1 and the disposal area R2 corresponds to the distance between the central position P1 and the disposal position P2. When the abnormal area R3 exists and the input signal is an automatic disposal instruction, the processor 36 will generate a disposal command according to the central position P1, the disposal position P2 and the abnormal indication. The treatment command includes a movement parameter and a time parameter. The movement parameter may be the swing angle of the head 120. The controller 28 actuates the driving element 24 according to the movement parameter, so that the linkage element 18 connected to the driving element 24 guides the head 120 to adjust a certain angle (i.e., the head 120 rotates along the +X, -X, +Y, and/or -Y directions as shown in FIG. 4), and the treatment position P2 is aligned with a point of the abnormal area R3 (for example, but not limited to the upper left corner P3 of the abnormal area R3), and starts to move and scan along the X or Y direction from there until the treatment position P2 passes through the entire abnormal area R3. Since the predetermined distance D1 between the imaging area R1 and the treatment area R2 corresponds to the distance between the central position P1 and the treatment position P2, the processor 36 can calculate how much distance and angle the treatment element 16 needs to move so that the treatment area R2 can be aligned with the abnormal area R3. The time parameter is the time required for the abnormal tissue to be ablated obtained by the processor 36 after calculation. The calculation of the time parameter needs to refer to the size of the abnormal area and the power parameter of the laser. In some embodiments, the user can input the power of the laser used in the input element 34, and the host 30 calculates the corresponding time parameter. The controller 28 first activates the driving element 24 to move the head 120 according to the movement parameter. After the treatment area R2 is aligned with the abnormal area R3, the gate 266 is activated to optically couple the output end 264 of the light guide 260 with the treatment element 16. At this time, the laser light output by the treatment element 16 can ablate the abnormal tissue in the abnormal area R3. After the time parameter ends, the controller 28 activates the gate 266 to close to stop the ablation action on the abnormal tissue in the abnormal area R3. In this embodiment, the laser device 40 is manually activated, that is, when the user inputs the automatic treatment command, he manually turns on the laser device 40 to emit laser light.

在一些實施例中,處置元件16停止對異常區域進行消融動作後,控制器28將再依據移動參數致動驅動元件24使連動元件18牽引頭部120進行一定角度的調整,該調整角度及位移值不變,然調整方向與原方向相反,即使得熱影像擷取組件14可再重新擷取該經處置後的異常區域之熱影像,以判斷異常區域是否仍存在。 In some embodiments, after the treatment element 16 stops ablating the abnormal area, the controller 28 will actuate the driving element 24 according to the movement parameter to adjust the linkage element 18 to guide the head 120 to a certain angle. The adjustment angle and displacement value remain unchanged, but the adjustment direction is opposite to the original direction, so that the thermal image acquisition component 14 can re-capture the thermal image of the abnormal area after treatment to determine whether the abnormal area still exists.

在一些實施例中,熱影像內視鏡系統包含雷射裝置40,例如Nd:YAG雷射之532奈米波段、KTP雷射之532奈米波段、Er:YAG雷射之2,940奈米波段或800~980奈米的二極體(diode)雷射。雷射裝置40包 含出光管400。出光管400與導光件260的輸入端262相耦合。雷射裝置40被致動時,由出光管400發出雷射光源至輸入端262。雷射裝置40可以由使用者人工手動開啟,也可以由控制器28依據處置命令而致動。 In some embodiments, the thermal imaging endoscope system includes a laser device 40, such as a 532 nm band Nd:YAG laser, a 532 nm band KTP laser, a 2,940 nm band Er:YAG laser, or a 800-980 nm diode laser. The laser device 40 includes a light output tube 400. The light output tube 400 is coupled to the input end 262 of the light guide 260. When the laser device 40 is activated, the laser light source is emitted from the light output tube 400 to the input end 262. The laser device 40 can be manually turned on by the user, or it can be activated by the controller 28 according to the treatment command.

在一些實施例中,該輸入訊號為自動處置指令時,處理器36將產生一處置命令。控制器28依據處置命令,在致動閘門266以使該導光件260之該輸出端264耦合於該處置元件16步驟前,控制器28先致動雷射裝置40。如此,控制器28在控制閘門266打開時,雷射光源得經由出光管400、導光件260、處置元件16而照射到處置區域R2。 In some embodiments, when the input signal is an automatic processing instruction, the processor 36 will generate a processing command. According to the processing command, the controller 28 first activates the laser device 40 before actuating the gate 266 to couple the output end 264 of the light guide 260 to the processing element 16. In this way, when the controller 28 controls the gate 266 to open, the laser light source can be irradiated to the processing area R2 through the light output tube 400, the light guide 260, and the processing element 16.

在一些實施例中,異常區域存在,且輸入元件34所接收的輸入訊號為自動移動指令時,處理器36將依據中央位置P1、處置位置P2及異常標示產生移動參數。移動參數為頭部120之擺動角度,由控制器28依據此移動參數致動驅動元件24擺動,使連接驅動元件24的連動元件18牽引頭部120進行一定角度的調整,而將處置區域R2對準異常區域。 In some embodiments, when an abnormal area exists and the input signal received by the input element 34 is an automatic movement command, the processor 36 will generate a movement parameter according to the central position P1, the treatment position P2 and the abnormal indication. The movement parameter is the swing angle of the head 120. The controller 28 actuates the drive element 24 to swing according to the movement parameter, so that the linkage element 18 connected to the drive element 24 guides the head 120 to adjust a certain angle, and the treatment area R2 is aligned with the abnormal area.

請再參考圖1,熱影像內視鏡系統可包含雷射裝置40,雷射裝置40包含出光管400。出光管400與導光件260的輸入端262相耦合。雷射裝置40被致動時,由出光管400發出雷射光源至輸入端262。 Please refer to FIG. 1 again. The thermal imaging endoscope system may include a laser device 40, and the laser device 40 includes a light output tube 400. The light output tube 400 is coupled to the input end 262 of the light guide 260. When the laser device 40 is activated, the laser light source is emitted from the light output tube 400 to the input end 262.

在一些實施例中,使用者已藉由控制器28的遙桿27而將處置區域R2對準處置位置P2,因此,使用者可以僅利用輸入元件34進行處置動作。當輸入元件34接收的輸入訊號為手動處置指令時,控制器28依據手動處置指令致動閘門266使導光件260之輸出端264與處置元件16光耦合。當雷射裝置40開啟時,雷射光源可經由出光管400、導光件260、處置元件16而照射到異常區域。 In some embodiments, the user has aligned the treatment area R2 with the treatment position P2 by the remote control 27 of the controller 28, so the user can perform the treatment action only by using the input element 34. When the input signal received by the input element 34 is a manual treatment instruction, the controller 28 actuates the gate 266 according to the manual treatment instruction to optically couple the output end 264 of the light guide 260 with the treatment element 16. When the laser device 40 is turned on, the laser light source can irradiate the abnormal area through the light output tube 400, the light guide 260, and the treatment element 16.

在一些實施例中,當輸入訊號為手動停止指令時,控制器28依據手動處置指令致動閘門266使導光件260之輸出端264與處置元件16停止光耦合,即使雷射裝置40開啟,雷射光源亦不得照射到異常區域而停止對異常組織的消融。 In some embodiments, when the input signal is a manual stop command, the controller 28 actuates the gate 266 according to the manual treatment command to stop the optical coupling between the output end 264 of the light guide 260 and the treatment element 16. Even if the laser device 40 is turned on, the laser light source cannot irradiate the abnormal area and stop ablation of the abnormal tissue.

在一些實施例中,雷射裝置40亦可由控制器28致動,當控制器28已依據移動參數將處置區域R2對準異常區域,且輸入訊號為手動處置指令時,控制器28致動雷射裝置40;當輸入訊號為手動停止指令時,控制器28不致動雷射裝置40。因此,雷射裝置40可根據手動處置指令及手動停止指令開啟或關閉。若選擇之雷射裝置40為不固定光源波長之雷射裝置40,於控制器28致動雷射裝置40之時,亦可依照功率參數調整雷射裝置40發射之雷射光的光源功率,設定並啟動雷射於預定功率,以符合使用者的需求,並達到異常組織消融的效果。 In some embodiments, the laser device 40 can also be activated by the controller 28. When the controller 28 has aligned the treatment area R2 with the abnormal area according to the movement parameters and the input signal is a manual treatment command, the controller 28 activates the laser device 40; when the input signal is a manual stop command, the controller 28 does not activate the laser device 40. Therefore, the laser device 40 can be turned on or off according to the manual treatment command and the manual stop command. If the selected laser device 40 is a laser device 40 with an unfixed light source wavelength, when the controller 28 activates the laser device 40, the light source power of the laser light emitted by the laser device 40 can also be adjusted according to the power parameter, and the laser can be set and activated at a predetermined power to meet the needs of the user and achieve the effect of ablation of abnormal tissue.

在一些實施例中,控制器28首先依據移動參數致動驅動元件24使頭部120作動,隨後致動閘門266使導光件260之輸出端264與處置元件16光耦合,此時由處置元件16輸出之雷射光可對異常區域的異常組織進行消融。於時間參數終了後,控制器28再致動閘門266關閉,以停止對異常區域的異常組織的消融動作。 In some embodiments, the controller 28 first activates the driving element 24 to move the head 120 according to the movement parameter, and then activates the gate 266 to optically couple the output end 264 of the light guide 260 with the treatment element 16. At this time, the laser light output by the treatment element 16 can ablate the abnormal tissue in the abnormal area. After the time parameter ends, the controller 28 activates the gate 266 to close to stop the ablation action on the abnormal tissue in the abnormal area.

在一些實施例中,若異常區域存在且其尺寸大於該上限尺寸時,處理器36將異常區域內的該些熱感應點A做為另一異常標示。另一異常標示採與前文所述之「尺寸小於上限尺寸」時之異常標示不同的方式,例如可為實線框,以使使用者可直觀的辨識該異常區域是否大於上限尺寸。處理器36並控制該顯示器32於視覺影像上顯示該另一異常標 示,另記錄該異常區域存在之位置、大小,以便使用者可以其他方式對該異常組織進行處理。在一些實施例中,異常區域的上限尺寸可以是10毫米。 In some embodiments, if an abnormal area exists and its size is larger than the upper limit size, the processor 36 uses the thermal sensing points A in the abnormal area as another abnormal mark. The other abnormal mark is different from the abnormal mark when the size is smaller than the upper limit size described above, for example, it can be a solid line frame, so that the user can intuitively identify whether the abnormal area is larger than the upper limit size. The processor 36 also controls the display 32 to display the other abnormal mark on the visual image, and records the location and size of the abnormal area, so that the user can process the abnormal tissue in other ways. In some embodiments, the upper limit size of the abnormal area can be 10 mm.

請復參考圖3,圖3係為依據一些實施例之熱影像內視鏡導管之截面圖。熱影像內視鏡導管10包含管體12、熱影像擷取組件14、處置元件16、及連動元件18。管體12一端具有頭部120,管體12的另一端具有連接部122。熱影像擷取組件14位於該頭部120,當頭部120進入人體體內進行熱影像拍攝時,熱影像擷取組件14自一攝像區域R1擷取熱影像,並將之轉換為影像訊號自該連接部122輸出。處置元件16包含處置頭160及光纖162。處置頭160位於頭部120,光纖162位於管體12內,光纖162的一端位於連接部122,另一端與處置頭160相耦合。處置元件16具有處置區域R2,處置區域R2位於攝像區域R1內。連動元件18位於管體12內並連接頭部120。其中,該連動元件18被致動時,連動該管體12的該頭部120作動。 Please refer to FIG. 3 again, which is a cross-sectional view of a thermal imaging endoscope catheter according to some embodiments. The thermal imaging endoscope catheter 10 includes a tube body 12, a thermal image capturing component 14, a processing element 16, and a linkage element 18. The tube body 12 has a head 120 at one end, and a connecting portion 122 at the other end. The thermal image capturing component 14 is located at the head 120. When the head 120 enters the human body to take thermal images, the thermal image capturing component 14 captures a thermal image from a photographing area R1 and converts it into an image signal and outputs it from the connecting portion 122. The processing element 16 includes a processing head 160 and an optical fiber 162. The treatment head 160 is located in the head 120, the optical fiber 162 is located in the tube 12, one end of the optical fiber 162 is located in the connecting portion 122, and the other end is coupled to the treatment head 160. The treatment element 16 has a treatment area R2, and the treatment area R2 is located in the imaging area R1. The linkage element 18 is located in the tube 12 and connected to the head 120. When the linkage element 18 is activated, the head 120 of the tube 12 is linked to actuate.

在一些實施例中,熱影像內視鏡導管10可作為內視鏡系統的一次性可拋棄式導管。使用者可手動將管體12具有頭部120的一端推入人體需進行熱影像探測之區域。在一些實施例中,使用者可搭配控制器28來致動驅動元件24對頭部120進行較細微幅度的調整。控制器28另可與主機30連接,使用者可於主機30上輸入移動指令,使控制器28致動驅動元件24。 In some embodiments, the thermal imaging endoscope catheter 10 can be used as a disposable catheter for an endoscope system. The user can manually push the end of the tube 12 having the head 120 into the area of the human body where thermal imaging detection is required. In some embodiments, the user can use the controller 28 to actuate the drive element 24 to make a fine adjustment to the head 120. The controller 28 can also be connected to the host 30, and the user can input a movement command on the host 30 to enable the controller 28 to actuate the drive element 24.

請參考圖8,圖8係為依據一些實施例之熱影像異常區域判斷方法之流程圖。若未特別聲明,流程圖中步驟S10~S14的描述順序並 不能限制本發明之熱影像異常區域判斷方法之各步驟的執行順序。首先,以處理器36接收一視覺影像,該視覺影像包含二維排列的多個熱感應點A,每一熱感應點A具有一溫度(步驟S10)。依據此些熱感應點A的溫度,獲得視覺影像的平均溫度(步驟S12)。隨後判斷各熱感應點A的溫度是否比平均溫度高出一預定溫差,且該些熱感應點A是否具有兩個或以上的相鄰關係,若是,將該些相鄰的熱感應點A做為一異常區域(步驟S14)。 Please refer to FIG8, which is a flow chart of a thermal image abnormal area determination method according to some embodiments. Unless otherwise stated, the description order of steps S10 to S14 in the flow chart does not limit the execution order of each step of the thermal image abnormal area determination method of the present invention. First, a processor 36 receives a visual image, which includes a plurality of thermal sensing points A arranged in two dimensions, each thermal sensing point A having a temperature (step S10). Based on the temperatures of these thermal sensing points A, the average temperature of the visual image is obtained (step S12). Then determine whether the temperature of each thermal sensing point A is higher than the average temperature by a predetermined temperature difference, and whether these thermal sensing points A have two or more adjacent relationships. If so, these adjacent thermal sensing points A are regarded as an abnormal area (step S14).

在一些實施例中,二維排列包含第一軸及第二軸,例如將多個熱感應點A分為橫向的X軸及縱向的Y軸。異常區域的判斷方法更包含:沿第一軸,判斷各熱感應點A的溫度與平均溫度的差異是否有大於預定溫差。請復參考圖7C,例如判斷得熱感應點A43、A44、及A45之溫度較平均溫度高,且溫度差異大於預定溫差。熱感應點A43、A44、及A45彼此相鄰,則將該些相鄰的熱感應點A43,A44,A45做為第一子區域(步驟S140)。沿第二軸,判斷各熱感應點A的溫度與平均溫度的差異是否有大於預定溫差,例如判斷得熱感應點A34、A44、及A54之溫度較平均溫度高,且溫度差異大於預定溫差。熱感應點A34、A44、及A54彼此相鄰,則將該些相鄰的熱感應點A34,A44,A54做為第二子區域(步驟S142)。將第一子區域及第二子區域做為異常區域(步驟S144)。 In some embodiments, the two-dimensional arrangement includes a first axis and a second axis, for example, a plurality of thermal sensing points A are divided into a horizontal X axis and a vertical Y axis. The method for determining an abnormal region further includes: along the first axis, determining whether the difference between the temperature of each thermal sensing point A and the average temperature is greater than a predetermined temperature difference. Please refer to FIG. 7C again, for example, it is determined that the temperature of thermal sensing points A 43 , A 44 , and A 45 is higher than the average temperature, and the temperature difference is greater than the predetermined temperature difference. The thermal sensing points A 43 , A 44 , and A 45 are adjacent to each other, and the adjacent thermal sensing points A 43 , A 44 , and A 45 are used as the first sub-region (step S140). Along the second axis, it is determined whether the difference between the temperature of each heat sensing point A and the average temperature is greater than a predetermined temperature difference. For example, it is determined that the temperature of the heat sensing points A 34 , A 44 , and A 54 is higher than the average temperature, and the temperature difference is greater than the predetermined temperature difference. The heat sensing points A 34 , A 44 , and A 54 are adjacent to each other, and the adjacent heat sensing points A 34 , A 44 , and A 54 are used as the second sub-area (step S142). The first sub-area and the second sub-area are used as abnormal areas (step S144).

請參考圖9,圖9係為依據一些實施例之熱影像異常區域顯示裝置之功能方塊圖。熱影像異常區域顯示裝置50包含接收模組500、處理模組520、及顯示模組540。接收模組500用以接收視覺影像,視覺影像為包含二維排列的多個熱感應點A,每一熱感應點A具有一溫度。該接 收模組500可連接熱影像內視鏡導管10等,以接收一經擷取的視覺影像。視覺影像的各熱感應點A所表示之視野大小不受限制,僅需達到可精確表示偵測物(例如人體組織)的個別單位即可。處理模組520用以:依據該些熱感應點A的溫度,獲得一平均溫度;及判斷各具有相鄰關係的熱感應點A各自的溫度與該平均溫度之差異是否大於一預定溫差,若是,處理模組520將此些相鄰的熱感應點A作為異常區域。處理模組520將視覺影像及經辨識的異常區域傳輸至顯示模組540,由顯示模組540顯示該視覺影像及異常區域。視覺影像中非異常區域及異常區域可以不同顏色或標示的方式顯示,以便使用者可以直觀的獲取異常區域的資訊。 Please refer to FIG. 9, which is a functional block diagram of a thermal imaging abnormal area display device according to some embodiments. The thermal imaging abnormal area display device 50 includes a receiving module 500, a processing module 520, and a display module 540. The receiving module 500 is used to receive a visual image, which includes a plurality of thermal sensing points A arranged in two dimensions, each thermal sensing point A having a temperature. The receiving module 500 can be connected to a thermal imaging endoscope catheter 10, etc., to receive a captured visual image. The size of the field of view represented by each thermal sensing point A of the visual image is not limited, and only needs to reach an individual unit that can accurately represent the detected object (such as human tissue). The processing module 520 is used to: obtain an average temperature based on the temperatures of the heat sensing points A; and determine whether the difference between the temperature of each adjacent heat sensing point A and the average temperature is greater than a predetermined temperature difference. If so, the processing module 520 regards these adjacent heat sensing points A as abnormal areas. The processing module 520 transmits the visual image and the identified abnormal area to the display module 540, and the display module 540 displays the visual image and the abnormal area. The non-abnormal area and the abnormal area in the visual image can be displayed in different colors or marked so that the user can intuitively obtain information about the abnormal area.

請參考圖10,圖10係為依據一些實施例之熱影像處理主機之功能方塊圖。熱影像處理主機60包含顯示器600及處理器620。顯示器600與處理器620相連接。處理器620用以:接收一影像訊號,該影像訊號對應一視覺影像,該視覺影像包含二維排列之多個熱感應點A,每一熱感應點A具有一溫度;依據此些溫度,獲得一平均溫度;判斷具有相鄰關係的各熱感應點A的溫度與平均溫度之差異是否大於一預定溫差,若是,則將該些相鄰的熱感應點A做為一異常區域;及控制顯示器600顯示視覺影像及異常區域。其中,異常區域可以是一個或多個,且於顯示器600中以顏色或其他標示方式使使用者得以直觀的區分異常區域及非異常區域。 Please refer to FIG. 10 , which is a functional block diagram of a thermal image processing host according to some embodiments. The thermal image processing host 60 includes a display 600 and a processor 620. The display 600 is connected to the processor 620. The processor 620 is used to: receive an image signal, the image signal corresponds to a visual image, the visual image includes a plurality of thermal sensing points A arranged in two dimensions, each thermal sensing point A has a temperature; obtain an average temperature based on these temperatures; determine whether the difference between the temperature of each thermal sensing point A having a neighboring relationship and the average temperature is greater than a predetermined temperature difference, and if so, treat these neighboring thermal sensing points A as an abnormal area; and control the display 600 to display the visual image and the abnormal area. There may be one or more abnormal areas, and the display 600 may be marked with colors or other markings to allow the user to visually distinguish between abnormal areas and non-abnormal areas.

請參考圖11,圖11係為依據一些實施例之熱影像處理主機 60之處理器620的異常區域判斷步驟。在一些實施例中,二維排列包含第一軸及第二軸。處理器620判斷異常區域的步驟係:沿該第一軸,判斷相鄰的多個熱感應點A之該些溫度與平均溫度之差異是否大於一預定溫差,若是,則將該些相鄰的熱感應點A做為第一子區域(步驟S20);沿該第二軸,判斷相鄰的該些熱感應點A之該些溫度與該平均溫度之差異是否大於預定溫差,若是,則將該些相鄰的熱感應點做為第二子區域(步驟S22);及視覺影像中的各熱感應點A皆判斷完後,將第一子區域及第二子區域做為異常區域(步驟S24)。 Please refer to FIG. 11, which shows the abnormal area determination step of the processor 620 of the thermal image processing host 60 according to some embodiments. In some embodiments, the two-dimensional arrangement includes a first axis and a second axis. The steps for the processor 620 to determine the abnormal area are: along the first axis, determine whether the difference between the temperatures of the adjacent thermal sensing points A and the average temperature is greater than a predetermined temperature difference. If so, then use the adjacent thermal sensing points A as the first sub-region (step S20); along the second axis, determine whether the difference between the temperatures of the adjacent thermal sensing points A and the average temperature is greater than the predetermined temperature difference. If so, then use the adjacent thermal sensing points as the second sub-region (step S22); and visual After each thermal sensing point A in the image is judged, the first sub-region and the second sub-region are regarded as abnormal regions (step S24).

在一些實施例中,可就異常區域再做更進一步的判斷,處理器620判斷該異常區域的尺寸是否小於或等於上限尺寸,若是,處理器620控制顯示器600以第一種方式顯示視覺影像及異常區域。處理器620亦同時判斷異常區域的尺寸是否大於上限尺寸,若是,處理器620控制顯示器600以第二種方式顯示視覺影像及異常區域。上限尺寸的範圍可以參考選用的雷射的消融範圍或處置區域,例如使用Nd:YAG 1,064奈米波長之脈衝雷射時,其雷射光源可使組織10毫米範圍內的細胞死亡,即可以10毫米作為上限尺寸的範圍,若異常區域的尺寸小於或等於10毫米,處理器620可控制顯示器600以第一種方式顯示,若異常區域的尺寸大於10毫米,處理器620控制顯示器600以第二種方式顯示。 In some embodiments, a further determination may be made on the abnormal region. The processor 620 determines whether the size of the abnormal region is less than or equal to the upper limit size. If so, the processor 620 controls the display 600 to display the visual image and the abnormal region in a first manner. The processor 620 also determines whether the size of the abnormal region is greater than the upper limit size. If so, the processor 620 controls the display 600 to display the visual image and the abnormal region in a second manner. The upper limit size range can refer to the ablation range or treatment area of the selected laser. For example, when using a pulsed laser of Nd:YAG 1,064 nanometer wavelength, its laser light source can cause cell death within a 10 mm range of the tissue, that is, 10 mm can be used as the upper limit size range. If the size of the abnormal area is less than or equal to 10 mm, the processor 620 can control the display 600 to display in the first way. If the size of the abnormal area is greater than 10 mm, the processor 620 controls the display 600 to display in the second way.

綜上所述,在一些實施例中,熱影像內視鏡系統可以熱影像內視鏡導管10及控制裝置20來達到偵測人體異常組織及進行處置之效 果。熱影像異常區域判斷方法可透過視覺影像之熱感應點A判斷異常區域。熱影像異常區域顯示裝置50以及熱影像處理主機60得以處理模組520或處理器620判斷異常區域並由顯示模組540或顯示器600顯示視覺影像及異常區域。 In summary, in some embodiments, the thermal imaging endoscope system can achieve the effect of detecting abnormal tissues in the human body and treating them by using the thermal imaging endoscope catheter 10 and the control device 20. The thermal imaging abnormal area judgment method can judge the abnormal area through the heat sensing point A of the visual image. The thermal imaging abnormal area display device 50 and the thermal imaging processing host 60 can judge the abnormal area by the processing module 520 or the processor 620 and display the visual image and the abnormal area by the display module 540 or the display 600.

10:熱影像內視鏡導管 10: Thermal imaging endoscope catheter

12:管體 12: Tube body

120:頭部 120: Head

122:連接部 122: Connection part

20:控制裝置 20: Control device

27:遙桿 27: Remote control

30:主機 30: Host

32:顯示器 32: Display

34:輸入元件 34: Input components

36:處理器 36: Processor

40:雷射裝置 40: Laser device

400:出光管 400: light pipe

Claims (20)

一種熱影像內視鏡系統,包括:一熱影像內視鏡導管,包含:一管體,該管體一端具有一頭部;一熱影像擷取組件,位於該頭部並用以自一攝像區域擷取一熱影像並將之轉換為一影像訊號,該影像訊號用以產生一視覺影像,該視覺影像包含多個熱感應點,且該些熱感應點具有一平均溫度,相鄰的各該熱感應點的一溫度與該平均溫度之差異大於一預定溫差時該視覺影像具有一異常區域,且該異常區域的一尺寸小於或等於一上限尺寸時,將該異常區域內的該些熱感應點做為一異常標示,該上限尺寸為10毫米;一處置元件,位於該管體內且該處置元件的一端位於該頭部,該處置元件具有一處置區域,該處置區域位於該攝像區域內;及一連動元件,位於該管體內並連接該頭部;及一控制裝置,包含:一接收元件,用以接收一處置命令;一驅動元件,連接該連動元件;一導光組件,包含一導光件及一閘門,該導光件包含一輸入端及一輸出端,該閘門被致動以選擇性地將該導光件之該輸出端耦合與不耦合於該處置元件;及一控制器,依據該處置命令,致動該驅動元件以使該連動元件連動該頭部作動、以及致動該閘門。 A thermal image endoscope system, including: a thermal image endoscope catheter, including: a tube body with a head at one end; a thermal image capture component located at the head and used to capture images from an imaging area Capture a thermal image and convert it into an image signal. The image signal is used to generate a visual image. The visual image includes multiple thermal sensing points, and the thermal sensing points have an average temperature. Each adjacent thermal image has an average temperature. When the difference between a temperature of the thermal sensing point and the average temperature is greater than a predetermined temperature difference, the visual image has an abnormal area, and when a size of the abnormal area is less than or equal to an upper limit size, the thermal sensors in the abnormal area are The point is used as an abnormality mark, and the upper limit size is 10 mm; a processing element, located in the tube body and one end of which is located at the head, the processing element having a processing area, the processing area being located in the imaging area; and a linkage element, located in the tube body and connected to the head and a control device, comprising: a receiving element for receiving a processing command; a driving element connected to the linkage element; a light guide assembly, comprising a light guide and a gate, the light guide comprising an input terminal and an output terminal, the gate being actuated to selectively couple and uncouple the output terminal of the light guide to the treatment element; and a controller actuating the driving element according to the treatment command so that the The linkage element links the movement of the head and actuates the gate. 如請求項1所述之熱影像內視鏡系統,包含: 一主機,包含:一顯示器;一輸入元件,用以接收一輸入訊號;及一處理器,依據該影像訊號,使該顯示器顯示該視覺影像;該處理器依據該輸入訊號而輸出該處置命令。 The thermal imaging endoscope system as described in claim 1 comprises: a host computer comprising: a display; an input element for receiving an input signal; and a processor for causing the display to display the visual image according to the image signal; the processor outputs the processing command according to the input signal. 如請求項2所述之熱影像內視鏡系統,其中,該處理器對該影像訊號進行一異常標示程序,以使該顯示器選擇性地於該視覺影像上顯示該異常標示。 A thermal imaging endoscope system as described in claim 2, wherein the processor performs an abnormality marking process on the image signal so that the display selectively displays the abnormality mark on the visual image. 如請求項3所述之熱影像內視鏡系統,其中,該視覺影像包含二維排列之多個熱感應點,每一該熱感應點具有一溫度,該處理器執行該異常標示程序係執行:判斷是否存在該異常區域,該異常區域包含相鄰該些熱感應點且該些相鄰的熱感應點之該些溫度與該平均溫度之差異是否大於該預定溫差;及當該異常區域存在且該異常區域的一尺寸小於或等於一上限尺寸時,將該異常區域內的該些熱感應點做為該異常標示,該處理器控制該顯示器於該視覺影像上顯示該異常標示。 The thermal image endoscope system as described in claim 3, wherein the visual image includes a plurality of thermal sensing points arranged in a two-dimensional manner, each of the thermal sensing points has a temperature, and the processor executes the abnormality flagging program. : Determine whether the abnormal area exists, the abnormal area includes the adjacent thermal sensing points, and whether the difference between the temperatures of the adjacent thermal sensing points and the average temperature is greater than the predetermined temperature difference; and when the abnormal area exists And when a size of the abnormal area is less than or equal to an upper limit size, the thermal sensing points in the abnormal area are used as the abnormal mark, and the processor controls the display to display the abnormal mark on the visual image. 如請求項4所述之熱影像內視鏡系統,其中,該視覺影像具有一中央位置及一處置位置,該中央位置係對應該攝像區域,該處置位置係對應該處置區域,當該異常區域存在且該輸入訊號為一自動處置指令時,該處理器依據該中央位置、該處置位置及該異常標示,輸出該處置命令,該處置命令包含一移動參數及一時間參數,該時間參數之 計算參照該異常區域的該尺寸大小,該控制器依據該移動參數致動該驅動元件以使該連動元件連動該頭部作動、以及致動該閘門以使該導光件之該輸出端耦合於該處置元件直至該時間參數終了。 The thermal imaging endoscope system as described in claim 4, wherein the visual image has a central position and a disposal position, the central position corresponds to the imaging area, the disposal position corresponds to the disposal area, when the abnormal area exists and the input signal is an automatic disposal instruction, the processor outputs the disposal command according to the central position, the disposal position and the abnormal indication, the disposal command includes a movement parameter and a time parameter, the time parameter is calculated with reference to the size of the abnormal area, the controller actuates the driving element according to the movement parameter so that the linkage element links the head to move, and actuates the gate so that the output end of the light guide is coupled to the disposal element until the time parameter ends. 如請求項5所述之熱影像內視鏡系統,包含一雷射裝置,該雷射裝置包含一出光管;該出光管耦合於該導光件之該輸入端;該雷射裝置被致動時,於該出光管發出一雷射光。 The thermal imaging endoscope system as described in claim 5 includes a laser device, which includes a light emitting tube; the light emitting tube is coupled to the input end of the light guide; when the laser device is activated, a laser light is emitted from the light emitting tube. 如請求項6所述之熱影像內視鏡系統,其中,該控制器在致動該閘門以使該導光件之該輸出端耦合於該處置元件步驟前,該控制器致動該雷射裝置。 A thermal imaging endoscope system as described in claim 6, wherein the controller activates the laser device before activating the gate to couple the output end of the light guide to the treatment element step. 如請求項4所述之熱影像內視鏡系統,其中,該視覺影像具有一中央位置及一處置位置,該中央位置係對應該攝像區域,該處置位置係對應該處置區域,當該異常區域存在且該輸入訊號為一自動移動指令時,該處理器依據該中央位置、該處置位置及該異常標示,輸出的該處置命令包含一移動參數,該控制器依據該移動參數致動該驅動元件以使該連動元件連動該頭部作動。 The thermal imaging endoscope system as described in claim 4, wherein the visual image has a central position and a disposal position, the central position corresponds to the photographing area, and the disposal position corresponds to the disposal area. When the abnormal area exists and the input signal is an automatic movement command, the processor outputs the disposal command including a movement parameter according to the central position, the disposal position and the abnormal indication, and the controller activates the driving element according to the movement parameter so that the linkage element links the head to move. 如請求項4或8所述之熱影像內視鏡系統,包含一雷射裝置,該雷射裝置包含一出光管;該出光管耦合於該導光件之該輸入端;該雷射裝置被致動時,於該出光管發出一雷射光。 The thermal imaging endoscope system as described in claim 4 or 8 comprises a laser device, the laser device comprises a light emitting tube; the light emitting tube is coupled to the input end of the light guide; when the laser device is activated, a laser light is emitted from the light emitting tube. 如請求項9所述之熱影像內視鏡系統,其中,當該輸入訊號為一手動處置指令時,該控制器致動該閘門以使該導光件之該輸出端耦合於該處置元件。 A thermal imaging endoscope system as described in claim 9, wherein when the input signal is a manual processing instruction, the controller actuates the gate to couple the output end of the light guide to the processing element. 如請求項10所述之熱影像內視鏡系統,其中,當該輸 入訊號為一停止處置指令時,該控制器致動該閘門以使該導光件之該輸出端不耦合於該處置元件。 A thermal imaging endoscope system as described in claim 10, wherein when the input signal is a stop processing instruction, the controller actuates the gate so that the output end of the light guide is not coupled to the processing element. 如請求項11所述之熱影像內視鏡系統,其中,當該輸入訊號為該手動處置指令時,該控制器致動該雷射裝置;當該輸入訊號為該停止處置指令時,該控制器不致動該雷射裝置。 The thermal imaging endoscope system as described in claim 11, wherein when the input signal is the manual processing instruction, the controller activates the laser device; when the input signal is the stop processing instruction, the controller does not activate the laser device. 如請求項4所述之熱影像內視鏡系統,其中,當該異常區域存在且大於該上限尺寸時,將該異常區域內的該些熱感應點做為另一異常標示,該處理器控制該顯示器於該視覺影像上顯示該另一異常標示。 The thermal image endoscope system as described in claim 4, wherein when the abnormal area exists and is larger than the upper limit size, the thermal sensing points in the abnormal area are used as another abnormality mark, and the processor controls The display displays the other abnormality mark on the visual image. 一種熱影像內視鏡導管,包含:一管體,該管體一端具有一頭部,該管體之另一端具有一連接部;一熱影像擷取組件,位於該頭部並用以自一攝像區域擷取一熱影像並將之轉換為一影像訊號自該連接部輸出,該影像訊號用以產生一視覺影像,該視覺影像包含多個熱感應點且該些熱感應點具有一平均溫度,相鄰的各該熱感應點的一溫度與該平均溫度之差異大於一預定溫差時該視覺影像具有一異常區域,且該異常區域的一尺寸小於或等於一上限尺寸時,將該異常區域內的該些熱感應點做為一異常標示,該上限尺寸為10毫米;一處置元件,包含一處置頭及一光纖,該光纖位於該管體內且該處置頭位於該頭部,該光纖一端位於該連接部,該光纖的另一端耦合於該處置頭,該處置元件具有一處置區域,該處置區域位於該攝像區域內;及 一連動元件,位於該管體內並連接該頭部,其中,該連動元件被致動時,連動該管體的該頭部作動。 A thermal imaging endoscope catheter comprises: a tube body, one end of which has a head, and the other end of which has a connection portion; a thermal image acquisition component, located at the head and used to capture a thermal image from a photographing area and convert it into an image signal and output it from the connection portion, the image signal is used to generate a visual image, the visual image includes a plurality of thermal sensing points and the thermal sensing points have an average temperature, the visual image has an abnormal area when the difference between a temperature of each adjacent thermal sensing point and the average temperature is greater than a predetermined temperature difference, and a temperature of the abnormal area is When the size is less than or equal to an upper limit size, the thermal sensing points in the abnormal area are used as an abnormality mark, and the upper limit size is 10 mm; a treatment element, including a treatment head and an optical fiber, the optical fiber is located in the tube body and the treatment head is located in the head, one end of the optical fiber is located in the connection part, the other end of the optical fiber is coupled to the treatment head, the treatment element has a treatment area, the treatment area is located in the imaging area; and a linkage element is located in the tube body and connected to the head, wherein the linkage element is When moving, the head of the pipe body is linked to move. 一種熱影像異常區域判斷方法,包含:接收一視覺影像,該視覺影像包含二維排列之多個熱感應點,每一該熱感應點具有一溫度;依據該些溫度,獲得一平均溫度;判斷相鄰的該些熱感應點之該些溫度與該平均溫度之差異是否大於一預定溫差,若是,則將該些相鄰的熱感應點做為一異常區域;及該異常區域的一尺寸小於或等於一上限尺寸時,將該異常區域內的該些熱感應點做為一異常標示,該上限尺寸為10毫米。 A method for judging abnormal areas in thermal images, including: receiving a visual image, the visual image including a plurality of two-dimensionally arranged thermal sensing points, each of the thermal sensing points having a temperature; obtaining an average temperature based on these temperatures; judging Whether the difference between the temperatures of the adjacent thermal sensing points and the average temperature is greater than a predetermined temperature difference, if so, then the adjacent thermal sensing points are regarded as an abnormal area; and a size of the abnormal area is less than Or when it is equal to an upper limit size, the thermal sensing points in the abnormal area are used as an abnormality mark. The upper limit size is 10 mm. 如請求項15所述之熱影像異常區域判斷方法,其中,該二維包含一第一軸及一第二軸,該判斷步驟包含:沿該第一軸,判斷相鄰的該些熱感應點之該些溫度與該平均溫度之差異是否大於該預定溫差,若是,則將該些相鄰的熱感應點做為一第一子區域;沿該第二軸,判斷相鄰的該些熱感應點之該些溫度與該平均溫度之差異是否大於該預定溫差,若是,則將該些相鄰的熱感應點做為一第二子區域;及將該第一子區域及該第二子區域做為該異常區域。 The thermal image abnormal area determination method as described in claim 15, wherein the two dimensions include a first axis and a second axis, and the determination step includes: determining the adjacent thermal sensing points along the first axis. Whether the difference between the temperatures and the average temperature is greater than the predetermined temperature difference, if so, the adjacent thermal sensing points are regarded as a first sub-region; along the second axis, determine the adjacent thermal sensing points Whether the difference between the temperatures of the points and the average temperature is greater than the predetermined temperature difference, if so, then use the adjacent thermal sensing points as a second sub-area; and use the first sub-area and the second sub-area as the abnormal area. 一種熱影像異常區域顯示裝置,包含:一接收模組,用以接收一視覺影像,該視覺影像包含二維排列之多個熱感應點,每一該熱感應點具有一溫度; 一處理模組,用以:依據該些溫度,獲得一平均溫度;及判斷相鄰的該些熱感應點之該些溫度與該平均溫度之差異是否大於一預定溫差,若是,則將該些相鄰的熱感應點做為一異常區域;該異常區域的一尺寸小於或等於一上限尺寸時,將該異常區域內的該些熱感應點做為一異常標示,該上限尺寸為10毫米;及一顯示模組,用以顯示該視覺影像、該異常區域及該異常標示。 A thermal image abnormal area display device, including: a receiving module for receiving a visual image, the visual image includes a plurality of two-dimensionally arranged thermal sensing points, each of the thermal sensing points has a temperature; a processing module , used to: obtain an average temperature based on the temperatures; and determine whether the difference between the temperatures of the adjacent thermal sensing points and the average temperature is greater than a predetermined temperature difference. If so, then convert the adjacent thermal sensing points into The sensing point is used as an abnormal area; when a size of the abnormal area is less than or equal to an upper limit size, the thermal sensing points in the abnormal area are used as an abnormal mark, the upper limit size is 10 mm; and a display module A group is used to display the visual image, the abnormal area and the abnormal mark. 一種熱影像處理主機,包含:一顯示器;及一處理器,用以:接收一影像訊號,該影像訊號對應一視覺影像,該視覺影像包含二維排列之多個熱感應點,每一該熱感應點具有一溫度;依據該些溫度,獲得一平均溫度;判斷相鄰的該些熱感應點之該些溫度與該平均溫度之差異是否大於一預定溫差,若是,則將該些相鄰的熱感應點做為一異常區域;該異常區域的一尺寸小於或等於一上限尺寸時,將該異常區域內的該些熱感應點做為一異常標示,該上限尺寸為10毫米;及控制該顯示器顯示該視覺影像、該異常區域及該異常標示。 A thermal image processing host includes: a display; and a processor, used to: receive an image signal, the image signal corresponds to a visual image, the visual image includes a plurality of thermal sensing points arranged in two dimensions, each of the thermal The sensing point has a temperature; based on the temperatures, an average temperature is obtained; it is judged whether the difference between the temperatures of the adjacent thermal sensing points and the average temperature is greater than a predetermined temperature difference, and if so, the adjacent thermal sensing points are Thermal sensing points are used as an abnormal area; when a size of the abnormal area is less than or equal to an upper limit size, the thermal sensing points in the abnormal area are used as an abnormal mark, the upper limit size is 10 mm; and control the The display displays the visual image, the abnormal area and the abnormal mark. 如請求項18所述之熱影像處理主機,其中,該二維包含一第一軸及一第二軸,該處理器之該判斷步驟係為該處理器執行:沿該第一軸,判斷相鄰的該些熱感應點之該些溫度與該平均溫度之差異是否大於該預定溫差,若是,則將該些相鄰的熱感應點做為一第一 子區域;沿該第二軸,判斷相鄰的該些熱感應點之該些溫度與該平均溫度之差異是否大於該預定溫差,若是,則將該些相鄰的熱感應點做為一第二子區域;及將該第一子區域及該第二子區域做為該異常區域。 The thermal image processing host as described in claim 18, wherein the two dimensions include a first axis and a second axis, and the determination step of the processor is performed by the processor: determine the phase along the first axis. Whether the difference between the temperatures of the adjacent thermal sensing points and the average temperature is greater than the predetermined temperature difference, if so, then the adjacent thermal sensing points are regarded as a first sub-region; along the second axis, determine Whether the difference between the temperatures of the adjacent thermal sensing points and the average temperature is greater than the predetermined temperature difference, if so, then use the adjacent thermal sensing points as a second sub-region; and convert the first sub-region The area and the second sub-area are regarded as the abnormal area. 如請求項19所述之熱影像處理主機,其中,該處理器執行:判斷該異常區域的一尺寸小於或等於一上限尺寸時,控制該顯示器以一第一種方式顯示該視覺影像及該異常區域;及判斷該異常區域的該尺寸大於該上限尺寸時,控制該顯示器以一第二種方式顯示該視覺影像及該異常區域。 The thermal image processing host as described in claim 19, wherein the processor executes: when it is determined that a size of the abnormal area is less than or equal to an upper limit size, the display is controlled to display the visual image and the abnormal area in a first manner; and when it is determined that the size of the abnormal area is greater than the upper limit size, the display is controlled to display the visual image and the abnormal area in a second manner.
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