TWI826351B - Ｒ抗體,其藥物組合物及其應用 - Google Patents
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- A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
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- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
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- A—HUMAN NECESSITIES
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- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
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- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2869—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against hormone receptors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/94—Stability, e.g. half-life, pH, temperature or enzyme-resistance
Landscapes
- Health & Medical Sciences (AREA)
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- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
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- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
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- Epidemiology (AREA)
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- Oil, Petroleum & Natural Gas (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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- Proteomics, Peptides & Aminoacids (AREA)
- Microbiology (AREA)
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- Pulmonology (AREA)
- Endocrinology (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
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| CN201610954533.2A CN107987162A (zh) | 2016-10-27 | 2016-10-27 | Etar抗体，其药物组合物及其应用 |
| ??201610954533.2 | 2016-10-27 | ||
| CN201610954533.2 | 2016-10-27 |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN111018987B (zh) | 2014-12-05 | 2023-11-21 | 鸿运华宁（杭州）生物医药有限公司 | 一种能与人内皮素受体特异性结合的抗体及其应用 |
| FR3077574B1 (fr) * | 2018-02-07 | 2022-04-01 | Commissariat Energie Atomique | Anticorps dirige contre le sous-type a des recepteurs aux endothelines et ses utilisations. |
| MX2021009851A (es) | 2019-02-18 | 2021-09-10 | Lilly Co Eli | Formulacion de anticuerpos terapeuticos. |
| CN112239507A (zh) * | 2019-07-17 | 2021-01-19 | 鸿运华宁（杭州）生物医药有限公司 | ETA抗体与TGF-β Trap的融合蛋白质，以及其药物组合物和应用 |
| CN115141276A (zh) * | 2021-03-31 | 2022-10-04 | 鸿运华宁（杭州）生物医药有限公司 | 一种能与人内皮素受体特异性结合的抗体及其在糖尿病肾病和慢性肾病治疗中的应用 |
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| CN101426527A (zh) * | 2006-02-03 | 2009-05-06 | 米迪缪尼有限公司 | 蛋白质制剂 |
| JP2010138165A (ja) * | 2008-11-14 | 2010-06-24 | Sekisui Chem Co Ltd | 抗ヒトエンドセリン受容体タイプａモノクローナル抗体、並びに、ハイブリドーマ |
| CN104513313A (zh) * | 2013-09-27 | 2015-04-15 | 杭州鸿运华宁生物医药工程有限公司 | 一种跨膜受体的单克隆抗体的筛选方法 |
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| CN111018987B (zh) * | 2014-12-05 | 2023-11-21 | 鸿运华宁（杭州）生物医药有限公司 | 一种能与人内皮素受体特异性结合的抗体及其应用 |
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Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101426527A (zh) * | 2006-02-03 | 2009-05-06 | 米迪缪尼有限公司 | 蛋白质制剂 |
| JP2010138165A (ja) * | 2008-11-14 | 2010-06-24 | Sekisui Chem Co Ltd | 抗ヒトエンドセリン受容体タイプａモノクローナル抗体、並びに、ハイブリドーマ |
| CN104513313A (zh) * | 2013-09-27 | 2015-04-15 | 杭州鸿运华宁生物医药工程有限公司 | 一种跨膜受体的单克隆抗体的筛选方法 |
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| US20230346932A1 (en) | 2023-11-02 |
| AU2017273959A1 (en) | 2019-01-03 |
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| US20190134196A1 (en) | 2019-05-09 |
| EP3476864A4 (en) | 2020-02-12 |
| EP3476864A1 (en) | 2019-05-01 |
| JP2019523764A (ja) | 2019-08-29 |
| KR20190013918A (ko) | 2019-02-11 |
| CA3025714A1 (en) | 2017-12-07 |
| AU2017273959B2 (en) | 2024-08-01 |
| KR102669444B1 (ko) | 2024-05-28 |
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