TWI783823B - Production method of composition with anti-blu ray protective capability - Google Patents

Production method of composition with anti-blu ray protective capability Download PDF

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TWI783823B
TWI783823B TW110146739A TW110146739A TWI783823B TW I783823 B TWI783823 B TW I783823B TW 110146739 A TW110146739 A TW 110146739A TW 110146739 A TW110146739 A TW 110146739A TW I783823 B TWI783823 B TW I783823B
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composition
blue light
extract
honeysuckle
myrobalan
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TW202322709A (en
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許長祿
陳怡妗
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健茂生物科技股份有限公司
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Abstract

The present invention relates to a production method of a composition with anti-blu ray protective capability that includes the following steps: a physical wall breaking and ingredient preparation step, an inoculation step, a fermentation step, and a mixing step. The advantages of the production method of a composition with anti-blu ray protective capability of the present invention are that, first, the physical wall breaking and ingredient preparation step of the lonicerae flos and chebulae fructus is conducted; then the aforementioned processed chebulae fructus undergoes an inoculation step using two strains of germ of Saccharomyces cerevisiae and Lactobacillus gasseri with an inoculation ratio to be between 30~60:40~70 respectively; next, after the fermentation step is processed, the lonicerae flos that has completed the physical wall breaking process and the fermented chebulae fructus are extracted and sterilized; finally, the mixing step is carried out to produce a composition with anti-blu ray protective capability by mixing the aforementioned two processed ingredients in different proportions.

Description

具有抗藍光保護力的組合物之製造方法Composition with protection against blue light and method of manufacture

本發明係關於組合物的製造方法,更詳而言之,特別係指一種具有抗藍光保護力的組合物之製造方法。 The present invention relates to the preparation method of the composition, more specifically, to a preparation method of the composition with anti-blue light protection ability.

藍光係一種可見光,其波長約400-500奈米,能量較高,如長時間照射人體會對人體有損傷;普遍民眾都長時間使用電子產品進行娛樂或者工作,而許多電子產品,如手機、電腦、平板...等產品,都會有藍光進行色彩的調整,長期使用下,對於眼睛的傷害非常嚴重。 Blue light is a kind of visible light with a wavelength of about 400-500 nanometers and high energy. If it is exposed to the human body for a long time, it will damage the human body; the general public uses electronic products for entertainment or work for a long time, and many electronic products, such as mobile phones, Products such as computers, tablets, etc. will have blue light to adjust the color. If used for a long time, it will seriously damage the eyes.

金銀花又名忍冬、銀花以及雙花…等別名,其表面為黃白色或者綠白色,貯久色漸深;訶子原稱訶黎勒,穗狀花序腋生或頂生,有時又組成圓 錐花序,核果堅硬,卵形或橢圓形,青色且無毛,成熟時變黑褐色,將兩者進行不同比例混合係可形成黃褐色、橘色…等色澤。 Honeysuckle is also known as honeysuckle, silver flower, double flower, etc. Its surface is yellow-white or green-white, and its color gradually becomes darker after long storage; round Cone inflorescence, drupe hard, ovate or oval, cyan and glabrous, dark brown when mature, mixing the two in different proportions can form yellowish brown, orange... and other colors.

所以本案申請人係採用金銀花與訶子的混合,其呈黃褐色、橘色…等色澤在吸收藍光上有非常良好功效為理論基礎,進而提出具有新穎性及進步性之本發明。 Therefore, the applicant of this case uses the mixture of honeysuckle and myrobalan, which is yellowish-brown, orange, etc., to have a very good effect on absorbing blue light as a theoretical basis, and then proposes a novel and progressive invention.

有鑑於此,本案申請人遂依其多年從事相關領域之研發經驗,針對前述之缺失進行深入探討,並依前述需求積極尋求解決之道,歷經長時間的努力研究與多次測試,終於完成本發明。 In view of this, the applicant in this case conducted in-depth discussions on the above-mentioned deficiencies based on his years of research and development experience in related fields, and actively sought solutions based on the above-mentioned needs. After long-term hard research and multiple tests, he finally completed this project. invention.

本發明具有抗藍光保護力的組合物之製造方法主要目的在於應用深淺不一的金銀花與訶子,進行不同比例的混合,讓其色澤形成橘色或者黃褐色…等暖色系列,探找到可良好的進行抗藍光的製程方法。 The main purpose of the manufacturing method of the composition with anti-blue light protection ability of the present invention is to use different shades of honeysuckle and myrobalan, and mix them in different proportions, so that the color can form a warm color series such as orange or yellowish brown. A good process method for anti-blue light.

本發明具有抗藍光保護力的組合物之製造方法次要目的在於運用不同比例混合金銀花 與訶子,進行色澤的調整,且經過色澤數字的定義找出抗藍光的較佳色澤範圍。 The secondary purpose of the manufacturing method of the composition with anti-blue light protection ability of the present invention is to use different proportions to mix honeysuckle With myrobalan, the color is adjusted, and the optimal color range for anti-blue light is found through the definition of the color number.

為達上述目的,本發明具有抗藍光保護力的組合物之製造方法,係包含有下列步驟: 破壁備料步驟:在常溫之下,分別對訶子(Terminalia chebula)以及金銀花(Lonicera japonica)進行表面的清洗、風乾,再運用破壁設備進行物理破壁,得到破壁後的金銀花與訶子;破壁後的金銀花與訶子各別進行萃取以及滅菌的動作,取得金銀花萃取液與訶子萃取液; 植菌步驟:將經過破壁步驟的訶子植入菌種,該菌種係釀酒酵母(Saccharomyces cerevisiae)以及加氏乳桿菌(Lactobacillus gasseri),其菌種植入比例介於30~60:40~70之間所組成,形成植菌液; 發酵步驟:植菌液在溫度25~40℃之間,經過10~60天的發酵過程中,該植菌液的接菌濃度達到106~109CFU/mL,再進行萃取以及滅菌的動作,形成訶子發酵萃取液。 In order to achieve the above-mentioned purpose, the preparation method of the composition with anti-blue light protection ability of the present invention comprises the following steps: The step of breaking the wall and preparing materials: under normal temperature, respectively treat Myrobalan ( Terminalia chebula ) and Honeysuckle ( Lonicera japonica ) Clean the surface, air-dry, and then use the wall-breaking equipment to physically break the wall to obtain the broken honeysuckle and myrobalan; the broken honeysuckle and myrobalan are extracted and sterilized separately to obtain the honeysuckle extract liquid and extract of Myrobalan; planting step: the Myrobalan that has gone through the wall-breaking step is implanted into strains, the strains are Saccharomyces cerevisiae and Lactobacillus gasseri , and the implantation ratio of the strains is Composed between 30~60:40~70 to form a plant liquid; Fermentation step: The plant liquid is fermented at a temperature of 25~40°C for 10~60 days, and the inoculation of the plant liquid When the bacterial concentration reaches 10 6 ~10 9 CFU/mL, extraction and sterilization are carried out to form the chebula fermented extract.

混合步驟:取金銀花萃取液以及訶子發酵萃取液進行混合,其混合比例介於30~50:50~70之間,形成具有抗藍光保護力的組合物。 Mixing step: take honeysuckle extract and myrobalan fermented extract and mix, the mixing ratio is between 30-50:50-70 to form a composition with anti-blue light protection ability.

藉由上述特徵,本發明具有抗藍光保護力的組合物之製造方法,其係透過將金銀花與訶子進行破壁備料步驟後,再將該訶子進行特定菌種植菌步驟以及特定參數進行發酵步驟,最後,將金銀花萃取液以及訶子發酵萃取液運用混合步驟進行不同比例的混合,即可完成具有抗藍光保護力的組合物。 With the above characteristics, the method of manufacturing the composition with anti-blue light protection ability of the present invention is to carry out the step of breaking the wall of honeysuckle and chebula, and then carry out the step of planting the chebula with specific bacteria and specific parameters. In the fermentation step, finally, the honeysuckle extract and the chebula fermented extract are mixed in different proportions through a mixing step to complete a composition with anti-blue light protection.

1:具有抗藍光保護力的組合物之製造方法 1: The preparation method of the composition with anti-blue light protective power

11:破壁備料步驟 11: The step of breaking the wall and preparing materials

12:植菌步驟 12: Bacteria planting step

13:發酵步驟 13: Fermentation step

14:混合步驟 14: Mixing step

圖1:本發明具有抗藍光保護力的組合物之製造方法較佳實施例流程示意圖。 Figure 1: Schematic flow chart of a preferred embodiment of the manufacturing method of the composition with anti-blue light protection ability of the present invention.

圖2:本發明具有抗藍光保護力的組合物穿透率檢測實驗結果圖。 Fig. 2: A diagram of the experimental results of the penetration rate detection of the composition with anti-blue light protection ability of the present invention.

為期許本發明之目的、功效、特徵及結構能夠有更為詳盡之瞭解,茲舉較佳實施例並配合圖式說明如後。 In order to allow a more detailed understanding of the purpose, function, features and structure of the present invention, the preferred embodiments are described below with accompanying drawings.

請參閱圖1,圖1為本發明具有抗藍光保護力的組合物之製造方法較佳實施例流程示意圖。 Please refer to FIG. 1 . FIG. 1 is a flow diagram of a preferred embodiment of the manufacturing method of the composition with anti-blue light protection ability of the present invention.

如圖1所示,本發明具有抗藍光保護力的組合物之製造方法1,係包含有下列步驟: 破壁備料步驟11:在常溫之下,分別對訶子(Terminalia chebula)以及金銀花(Lonicera japonica)進行表面的清洗、風乾,再運用破壁設備進行物理破壁,得到破壁後的金銀花與訶子各別進行萃取以及滅菌的動作,取得金銀花萃取液與訶子萃取液; 植菌步驟12:將經過破壁步驟的訶子植入菌種,該菌種係釀酒酵母(Saccharomyces cerevisiae)以及加氏乳桿菌(Lactobacillus gasseri),其菌種植入比例介於30~60:40~70之間所組成,形成植菌液; 發酵步驟13:植菌液在溫度25~40℃之間,經過10~60天的發酵過程中,該植菌液的接菌濃度達到106~109CFU/mL,再進行萃取以及滅菌的動作,形成訶子發酵萃取液。 As shown in Figure 1, the manufacturing method 1 of the composition with anti-blue light protection ability of the present invention includes the following steps: Breaking the wall and preparing materials Lonicera japonica ) was cleaned and air-dried, and then the wall was physically broken by using the wall-breaking equipment to obtain the broken honeysuckle and myrobalan, which were extracted and sterilized respectively to obtain the honeysuckle extract and the myrobalan extract; Bacteria planting step 12: implant the chebula that has undergone the wall-breaking step into strains, the strains are Saccharomyces cerevisiae and Lactobacillus gasseri , and the implantation ratio of the strains is between 30 and 60: 40~70 to form a plant liquid; Fermentation step 13: The temperature of the plant liquid is between 25~40°C, and after 10~60 days of fermentation, the concentration of the plant liquid reaches 10 6 ~10 9 CFU/mL, then extract and sterilize to form Myrobalan fermented extract.

混合步驟14:取金銀花萃取液以及訶子發酵萃取液進行混合,其混合比例介於30~50:50~70之間,形成具有抗藍光保護力的組合物。 Mixing step 14: Take the extract of honeysuckle and the fermented extract of Myrobalan, and mix them in a mixing ratio of 30-50:50-70 to form a composition with anti-blue light protection.

藉由上述特徵,本發明具有抗藍光保護力的組合物之製造方法1,其係透過將金銀花與訶子進行破壁備料步驟11後,再將該訶子進行特定菌 種植菌步驟12以及特定參數進行發酵步驟13,最後,將金銀花萃取液以及訶子發酵萃取液運用混合步驟14進行不同比例的混合,即可完成具有抗藍光保護力的組合物。 Based on the above features, the method 1 of the present invention for the composition having anti-blue light protection is to carry out the step 11 of breaking the wall of honeysuckle and chebula, and then subjecting the chebula to specific bacteria Step 12 of planting fungi and fermenting step 13 with specific parameters. Finally, the extract of honeysuckle and the fermented extract of Myrobalan are mixed in different proportions in step 14 to complete the composition with anti-blue light protection.

請參閱圖2,圖2為本發明具有抗藍光保護力的組合物穿透率檢測實驗結果圖。 Please refer to FIG. 2 . FIG. 2 is a graph showing the test results of the penetration rate of the composition with anti-blue light protection ability of the present invention.

為了檢測本發明具有抗藍光保護力的組合物之抗藍光功效,以下為抗藍光實驗檢測結果說明;本抗藍光實驗,係以三種檢測方式進行,分別為色澤、官能檢查以及穿透率;而其實驗檢測係採用四組對照組以及本發明進行測試;其中,第一組為取金銀花萃取液與水的混合液1ml~2ml,其比例介於10~30:70~90之間;第二組為取訶子萃取液與水的混合液1ml~2ml,其比例為1:40;第三組為取訶子萃取液與菌液的混合液1ml~2ml,其比例介於10~30:70~90之間;第四組為取金銀花萃取液與訶子萃取液的混合液1ml~2ml,其比例介於30~50:50~70之間;第五組為本發明之所得的組合物; 其實驗結果如下表(一)所示:

Figure 110146739-A0305-02-0010-1
In order to detect the anti-blue light effect of the composition with anti-blue light protection ability of the present invention, the following is the description of the test results of the anti-blue light experiment; the anti-blue light experiment is carried out in three detection methods, namely color, sensory inspection and penetration rate; and Its experimental detection system adopts four groups of control groups and the present invention to test; wherein, the first group is to get the mixed solution 1ml~2ml of honeysuckle extract and water, and its ratio is between 10~30:70~90; The second group is to take 1ml~2ml of the mixture of chebula extract and water, and the ratio is 1:40; the third group is to take 1ml~2ml of the mixture of chebula extract and water, and the ratio is 10~30 : between 70~90; the fourth group is to get the mixed solution 1ml~2ml of honeysuckle extract and chebula extract, its ratio is between 30~50:50~70; the fifth group is the gained of the present invention The composition; Its experimental result is as shown in the following table (1):
Figure 110146739-A0305-02-0010-1

如圖2及表(一)所示,檢測項目的色澤又稱色澤數字(PANTONE),係為國際標準色卡中顏色的編號,透過該編號係可讓色澤有更明確的數據進行分析;其中,該色澤數字(PANTONE)為127~131的範圍都為接近黃褐色、橘黃色、黃色..等暖色調的顏色;依照黃褐色、橘色…等色澤在吸收藍光上有非常良好功效為理論基礎,五組實驗品的混合後的色澤數字(PANTONE)分別依序為131、127、129、131以及128。 As shown in Figure 2 and Table (1), the color of the test item is also called the color number (PANTONE), which is the number of the color in the international standard color card. Through this number system, the color can be analyzed with more clear data; among them , the color number (PANTONE) ranges from 127 to 131, which are close to warm colors such as tan, orange, yellow.. etc.; according to the theory that tan, orange... and other colors have very good effects on absorbing blue light Basically, the mixed color numbers (PANTONE) of the five groups of experimental products are 131, 127, 129, 131 and 128 respectively.

如圖2及表(一)所示,該官能檢查係透過約405nm的藍光筆模擬藍光穿透,運用肉眼觀測的結果顯示,只有第五組的藍光照射結果為未穿 透,其餘都為可透光;其照射實驗結果為未穿透代表吸收抗藍光效果良好,所以藍光無法進行穿透實驗品,反之,照設結果為可透光代表吸收看藍光效果不達標,所以藍光能穿透實驗品,因此,該實驗結果第五組為較佳。 As shown in Figure 2 and Table (1), the sensory test is to simulate the penetration of blue light through a blue light pen of about 405nm. The results of the naked eye observation show that only the fifth group of blue light exposure results are not penetrated. The rest are light-transmissible; the result of the irradiation experiment is that it does not penetrate, which means that the anti-blue light effect is good, so the blue light cannot penetrate the test product. On the contrary, the light-transmitting result means that the blue light absorption effect is not up to standard. Therefore, the blue light can penetrate the test product, therefore, the fifth group is the better result of the test.

如圖2及表(一)所示,再將五組進行穿透率檢測,係運用分光光譜儀400nm的波長進行藍光的模擬,其檢測結果如圖2所示,其數據依序分別為0.564%、2.080%、1.223%、0.983%以及0.063%。 As shown in Figure 2 and Table (1), the five groups were tested for transmittance. The blue light was simulated by using a spectrometer with a wavelength of 400nm. The test results are shown in Figure 2, and the data are 0.564% in sequence. , 2.080%, 1.223%, 0.983%, and 0.063%.

其穿透率檢測的實驗結果顯示,該數值越低,代表實驗品吸收藍光的效果越好,能更好的進行抗藍光形成保護力,反之,當穿透率檢測的結果數值越高,代表實驗品吸收藍光的效果越差,不適合抗藍光,所以較無法形成保護力。因此,該實驗結果第五組為較佳,所以本發明的製造方法所得之組合物可獲得最佳的抗藍光效果。 The experimental results of the transmittance test show that the lower the value, the better the blue light absorption effect of the test product, and the better the protection against blue light. On the contrary, the higher the transmittance test result, the better The worse the effect of the experimental product on absorbing blue light, it is not suitable for anti-blue light, so it is less able to form a protective effect. Therefore, the fifth group of the experimental results is better, so the composition obtained by the manufacturing method of the present invention can obtain the best anti-blue light effect.

故,本發明在同類產品中具有極佳之進步性以及實用性,同時查遍國內外關於此類結構之技術資料文獻後,確實未發現有相同或近似之構造存在於本案申請之前,因此本案應已符合『創作性』、 『合於產業利用性』以及『進步性』的專利要件,爰依法提出申請之。 Therefore, the present invention has excellent progress and practicability among similar products. At the same time, after searching the technical data and documents about this type of structure at home and abroad, it is true that no identical or similar structure exists before the application of this case. Therefore, this case Should have met the "creativity", The patent requirements of "industrial applicability" and "progressiveness" should be applied for in accordance with the law.

唯,以上所述者,僅係本發明之較佳實施例而已,舉凡應用本發明說明書及申請專利範圍所為之其它等效結構變化者,理應包含在本發明之申請專利範圍內。 Only, what is described above is only a preferred embodiment of the present invention, and all other equivalent structural changes made by applying the description of the present invention and the scope of the patent application should be included in the scope of the patent application of the present invention.

1:具有抗藍光保護力的組合物之製造方法 1: The preparation method of the composition with anti-blue light protective power

11:破壁備料步驟 11: The step of breaking the wall and preparing materials

12:植菌步驟 12: Bacteria planting step

13:發酵步驟 13: Fermentation step

14:混合步驟 14: Mixing step

Claims (1)

一種具有抗藍光保護力的組合物之製造方法,係包含有下列步驟:A.破壁備料步驟:在常溫之下,分別對訶子(Terminalia chebula)以及金銀花(Lonicera japonica)進行表面的清洗、風乾,再運用破壁設備進行物理破壁得到破壁後的金銀花與訶子;破壁後的金銀花與訶子各別進行萃取以及滅菌的動作,取得金銀花萃取液與訶子萃取液;B.植菌步驟:將經過破壁後的訶子植入菌種,該菌種係釀酒酵母(Saccharomyces cerevisiae)以及加氏乳桿菌(Lactobacillus gasseri),其菌種植入比例介於30~60:40~70之間所組成,形成植菌液;C.發酵步驟:植菌液在溫度25~40℃之間,經過10~60天的發酵過程中,該植菌液的接菌濃度達到106~109CFU/mL,再進行萃取以及滅菌的動作,取得訶子發酵萃取液; D.混合步驟:取金銀花萃取液以及訶子發酵萃取液進行混合,其混合比例介於30~50:50~70之間,形成具有抗藍光保護力的組合物。 A method for preparing a composition with anti-blue light protection power, which includes the following steps: A. The step of breaking the wall and preparing materials: at room temperature, respectively clean the surface of Terminalia chebula ( Terminalia chebula ) and honeysuckle ( Lonicera japonica ) , air-dried, and then use the breaking equipment to physically break the wall to obtain the broken honeysuckle and myrobalan; the broken honeysuckle and myrobalan are respectively extracted and sterilized to obtain the honeysuckle extract and myrobalan extract B. Bacteria planting step: the chebula after breaking the wall is implanted into strains, the strains are Saccharomyces cerevisiae and Lactobacillus gasseri , and the implantation ratio of the strains is between 30 ~60: composed between 40~70 to form a plant liquid; C. Fermentation step: the plant liquid is fermented at a temperature of 25~40°C, and after 10~60 days of fermentation, the inoculation of the plant liquid The concentration reaches 10 6 ~10 9 CFU/mL, and then extract and sterilize to obtain the fermented extract of Myrobalan; D. Mixing step: take the extract of honeysuckle and the fermented extract of Myrobalan, and the mixing ratio is between 30~50: Between 50~70, a composition with anti-blue light protection is formed.
TW110146739A 2021-12-14 2021-12-14 Production method of composition with anti-blu ray protective capability TWI783823B (en)

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Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112190509A (en) * 2020-09-11 2021-01-08 广州优理氏生物科技有限公司 Composite plant extract and preparation method and application thereof
CN112386639A (en) * 2019-08-14 2021-02-23 百岳特生物技术(上海)有限公司 Application of golden camellia juice in preparing blue light resistant composition

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112386639A (en) * 2019-08-14 2021-02-23 百岳特生物技术(上海)有限公司 Application of golden camellia juice in preparing blue light resistant composition
CN112190509A (en) * 2020-09-11 2021-01-08 广州优理氏生物科技有限公司 Composite plant extract and preparation method and application thereof

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