TWI761374B - Skin coloring cosmetic composition - Google Patents

Skin coloring cosmetic composition Download PDF

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TWI761374B
TWI761374B TW106132954A TW106132954A TWI761374B TW I761374 B TWI761374 B TW I761374B TW 106132954 A TW106132954 A TW 106132954A TW 106132954 A TW106132954 A TW 106132954A TW I761374 B TWI761374 B TW I761374B
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skin
cosmetic composition
dihydroxyacetone
hair
coloring
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TW106132954A
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TW201813625A (en
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金惠園
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南韓商愛茉莉太平洋股份有限公司
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34Alcohols
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/35Ketones, e.g. benzophenone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/81Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/81Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
    • A61K8/8141Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides or nitriles thereof; Compositions of derivatives of such polymers
    • A61K8/8152Homopolymers or copolymers of esters, e.g. (meth)acrylic acid esters; Compositions of derivatives of such polymers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/84Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q1/00Make-up preparations; Body powders; Preparations for removing make-up
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin

Abstract

本發明涉及皮膚著色用化妝品組合物,更具體地涉及作為有效成分含有通過與皮膚角質層中含有的氨基酸的氨基反應來形成褐色化合物的類黑精(melanoidin)的二羥丙酮(dihydroxyacetone,DHA)和增強二羥丙酮的皮膚著色持續效果的赤藻酮糖(erythrulose)的皮膚著色用化妝品組合物。本發明涉及的皮膚著色用化妝品組合物,不僅浸透皮膚表面,而且浸透到皮膚角質層,能夠發揮優異的皮膚著色力,即使隨著時間的經過,也不會改變最初著色,能夠發揮優異的皮膚著色持續力,並且具有在塗抹部位能夠鮮明地保持很久的效果以及非常自然地顯現眉毛形狀的優點。The present invention relates to a cosmetic composition for skin coloring, and more particularly, to dihydroxyacetone (DHA) containing, as an active ingredient, a melanoidin (melanoidin) that forms a brown compound by reacting with an amino group of an amino acid contained in the stratum corneum of the skin And a skin coloring cosmetic composition of erythrulose which enhances the skin coloring lasting effect of dihydroxyacetone. The cosmetic composition for skin coloring according to the present invention can penetrate not only the skin surface but also the stratum corneum of the skin, and can exhibit excellent skin coloring power. The coloring lasts long, and it has the advantage that it can stay vivid for a long time on the application site, and the shape of the eyebrows is very natural.

Description

皮膚著色用化妝品組合物Cosmetic composition for skin coloring

本發明涉及皮膚著色用化妝品組合物,更具體地涉及局部皮膚著色用化妝品組合物。 The present invention relates to cosmetic compositions for skin coloring, and more particularly to topical skin coloring cosmetic compositions.

化妝品根據使用部位、使用目的、或產品的組成成分及形狀等分類為多種,可分為日常常用的基礎化妝品(護膚化妝品)、美妝用化妝品(彩妝化妝品)、身體護理(body care)化妝品(身體洗滌化妝品)、頭髮護理化妝品、口腔用化妝品、芳香性化妝品等。 Cosmetics are classified into various categories according to the part of use, purpose of use, or the composition and shape of the product. Body wash cosmetics), hair care cosmetics, oral cosmetics, aroma cosmetics, etc.

美妝用化妝品是在使用基礎產品後,塗抹在臉部、手指甲等身體上,賦予色彩感,從而顯現膚色之美,且能改善基礎產品無法遮蓋的皮膚缺陷。這種化妝品可以分類為打底妝和提亮化妝的化妝品,上述打底妝是通過均勻打理整個臉部的膚色、或遮蓋黃褐斑、雀斑等皮膚問題,使皮膚顯得更加健康且美麗,而上述提亮化妝是對嘴唇、眼睛、眉毛、臉腮、或手指甲等強調局部色彩、或者賦予陰影使其顯現立體感。提亮化妝使用口紅、腮紅、眼影(eye shadow)、眼線筆、眉筆、指甲油等。 Cosmetics for cosmetic use are applied on the face, fingernails and other bodies after using the basic products to give a sense of color, thereby showing the beauty of the complexion and improving the skin defects that the basic products cannot cover. This kind of cosmetic can be classified into base makeup and brightening makeup. The above-mentioned base makeup is to make the skin look healthier and more beautiful by evenly taking care of the complexion of the entire face, or covering skin problems such as melasma and freckles, The above-mentioned brightening makeup is to emphasize local color on lips, eyes, eyebrows, cheeks, or fingernails, or to give shadows to make them appear three-dimensional. Use lipstick, blush, eye shadow, eyeliner, eyebrow pencil, nail polish, etc. for brightening makeup.

其中能夠給人特別深的印象的是眉毛。一般來說,眼睛、鼻子、嘴可以通過化妝來某種程度改變形象,但是物理上改變形態是不可能的。只有眉毛可以改變形態。 Among them, the eyebrows are particularly impressive. Generally speaking, the eyes, nose, and mouth can be changed to some extent through makeup, but it is impossible to physically change the shape. Only eyebrows can change shape.

根據眉毛的形狀、大小、位置、以及顏色,人們的印象就會完全不同,所以無論東西古今,人們一直努力實現保持美麗的眉毛形狀及 顏色等,最近不僅女性,男性也為了留下好印象,對眉毛化妝傾注很深的關心。 Depending on the shape, size, position, and color of the eyebrows, people's impressions will be completely different, so people have been trying to maintain beautiful eyebrow shape and maintain beautiful eyebrows no matter what. Recently, not only women but also men have been paying close attention to eyebrow makeup in order to make a good impression, such as color and so on.

由於眉毛為由毛髮組成的身體組織的一部分,根據每個體的身體特性,眉毛毛髮位置、濃密程度、粗細等都有些差異,尤其是隨著年齡增大,就會出現眉毛毛髮數量逐漸減少或眉毛毛髮變稀等問題,很難持續保持優美的眉毛形狀。 Since the eyebrows are part of the body tissue composed of hair, according to the physical characteristics of each body, the position, thickness, thickness, etc. of the eyebrow hair are somewhat different, especially as the age increases, the number of eyebrow hair will gradually decrease or eyebrow hair will appear Problems such as thinning hair make it difficult to maintain a beautiful eyebrow shape consistently.

以往使用的眉筆、眉影、睫毛膏等的持續力短,洗臉時很容易洗掉,所以每次都需要補妝,很繁瑣。 The eyebrow pencil, eyebrow shadow, mascara, etc. used in the past have a short duration and are easy to wash off when washing your face, so you need to touch up makeup every time, which is very cumbersome.

為此,在下述專利文獻1中記載了不畫眉毛而以蓋章似的方式完成眉毛化妝的眉毛形狀的海綿,但是存在眉毛形狀持續時間非常短且實施有些不便的問題。 Therefore, the following Patent Document 1 describes an eyebrow-shaped sponge that completes the eyebrow makeup without drawing the eyebrows and seals the eyebrows, but there is a problem that the duration of the eyebrow shape is very short and the implementation is somewhat inconvenient.

另外,在下述專利文獻2中記載了眉毛化妝用眉筆組合物,上述眉毛化妝用眉筆組合物是在以往的眉毛化妝用眉筆組合物中加入油溶性薄膜形成劑,且含有利用乳化劑乳化的保濕劑及水溶性色素,從而提高持續性。但是,這只能是在皮膚表面短暫形成著色,著色力及著色保持力仍然弱,不能充分得到使用者所需的眉毛色彩,且不能形成彈性塗覆膜,眉毛的形狀不鮮明。 In addition, the following Patent Document 2 discloses an eyebrow pencil composition for eyebrow makeup, wherein an oil-soluble film-forming agent is added to a conventional eyebrow pencil composition for eyebrow makeup, and the above-mentioned eyebrow pencil composition for eyebrow makeup contains an emulsifier for use in eyebrow makeup. Emulsifying humectants and water-soluble pigments for improved durability. However, this can only temporarily form coloration on the skin surface, the coloring power and coloring retention are still weak, the eyebrow color required by the user cannot be fully obtained, and an elastic coating film cannot be formed, and the shape of the eyebrows is not clear.

為解決這些問題,有些女性選擇半永久紋眉。但是,半永久紋眉存在對皮膚刺激嚴重而引起皮膚問題,以及不能隨著時尚流行而改變眉毛形態及色彩的缺點。另外,大家知道隨著歲月的流逝,存在紋眉顏色變色為藍色的問題。 To solve these problems, some women opt for semi-permanent eyebrow tattoos. However, semi-permanent eyebrow tattoos have the disadvantages of severe irritation to the skin and causing skin problems, as well as the inability to change the shape and color of the eyebrows with fashion. In addition, everyone knows that as the years go by, there is a problem that the color of the tattooed eyebrows changes to blue.

為了以日光浴來得到健康膚色,使皮膚長時間暴露在陽光下,這樣就會引起隨著紫外線照射的曬傷(sunburn)而促進皮膚老化,並 可能誘發皮膚癌。因此,目前急需開發出更加安全的導出皮膚美黑的皮膚著色組合物。 In order to obtain a healthy complexion by sunbathing, the skin is exposed to the sun for a long time, which can promote the aging of the skin by causing sunburn with UV exposure, and May cause skin cancer. Therefore, there is an urgent need to develop safer skin tanning skin coloring compositions.

因此,目前迫切需要開發出皮膚著色化妝品組合物,上述化妝品組合物需要能夠發揮優異的著色力,不刺激皮膚,通過優異的著色保持力來顯現均勻且鮮豔顏色的自然膚色且能夠長久保持。 Therefore, there is an urgent need to develop a skin coloring cosmetic composition that exhibits excellent coloring power, does not irritate the skin, and exhibits a natural complexion of uniform and vivid color with excellent color retention power and can be maintained for a long time.

在這樣的技術背景之下,本發明人開發了作為有效成分含有二羥丙酮和赤藻酮糖的皮膚著色用化妝品組合物,該組合物提高了皮膚著色力及皮膚著色持續力。 Against such a technical background, the present inventors have developed a skin coloring cosmetic composition containing dihydroxyacetone and erythrulose as active ingredients, which improves skin coloring power and skin coloring sustainability.

現有技術文獻 prior art literature

專利文獻1:韓國公開實用新型第20-2011-0005915號(2011.06.15) Patent Document 1: Korean Utility Model Publication No. 20-2011-0005915 (2011.06.15)

專利文獻2:韓國公開專利第10-1996-0000193號(1996.01.25) Patent Document 2: Korean Patent Publication No. 10-1996-0000193 (1996.01.25)

為此,本發明人為了開發通過皮膚角質層中含有的氨基酸的氨基反應來形成褐色化合物的類黑精,並開發增強皮膚著色持續效果的皮膚著色用化妝品組合物,作為經過深入研究的結果,確認了作為有效成分含有二羥丙酮和赤藻酮糖的皮膚外用劑組合物具有優異的皮膚著色力和皮膚著色持續力,由此完成本發明。 Therefore, the inventors of the present invention have conducted intensive studies in order to develop a melanoidin which forms a brown compound by the amino reaction of amino acids contained in the stratum corneum of the skin, and to develop a cosmetic composition for skin coloring that enhances the lasting effect of skin coloring. It was confirmed that the skin external preparation composition containing dihydroxyacetone and erythrulose as active ingredients has excellent skin coloring power and skin coloring lasting power, thereby completing the present invention.

因此,本發明的目的是提供作為有效成分含有由二羥丙酮和赤藻酮糖組成的混合物的皮膚著色用化妝品組合物。 Therefore, the objective of this invention is to provide the cosmetic composition for skin coloring which contains the mixture which consists of dihydroxyacetone and erythrulose as an active ingredient.

為了達到上述目的,本發明提供作為有效成分含有由二羥丙酮和赤藻酮糖組成的混合物的皮膚著色用化妝品組合物。 In order to achieve the above-mentioned object, the present invention provides a cosmetic composition for skin coloring containing a mixture of dihydroxyacetone and erythrulose as active ingredients.

另外,本發明還提供利用上述皮膚著色用化妝品組合物製備的化妝品。 In addition, the present invention also provides a cosmetic prepared using the above-mentioned cosmetic composition for skin coloring.

此外,本發明還提供將由二羥丙酮和赤藻酮糖組成的混合物作為皮膚著色改善劑在製備皮膚著色用化妝品組合物或化妝品中的用途。 In addition, the present invention also provides the use of a mixture consisting of dihydroxyacetone and erythrulose as a skin coloration improving agent in the preparation of cosmetic compositions or cosmetics for skin coloring.

根據本發明涉及的皮膚著色用化妝品組合物,不僅浸透皮膚表面,而且浸透到皮膚角質層,從而能夠發揮優異的皮膚著色力,即使隨著時間的經過,也不會改變最初著色,能夠發揮優異的皮膚著色持續力,並且具有在塗抹部位能夠鮮明地保持很久的效果以及非常自然地顯現眉毛形狀的優點。 According to the cosmetic composition for skin coloring according to the present invention, not only the surface of the skin but also the stratum corneum of the skin can be permeated, and excellent skin coloring power can be exhibited. The skin coloration lasts for a long time, and it has the advantage that the effect can be vividly maintained for a long time on the application site, and the shape of the eyebrows is very natural.

圖1是將作為有效成分含有由二羥丙酮和赤藻酮糖組成的混合物的皮膚著色化妝品組合物塗抹在皮膚後,經過一天和九天的時間點上進行拍攝,對比皮膚著色持續力,判斷是否保持皮膚著色狀態的圖。 Figure 1 shows a skin coloring cosmetic composition containing a mixture of dihydroxyacetone and erythrulose as an active ingredient applied to the skin, and photographed at time points of one day and nine days to compare the skin coloring lasting power to determine whether Diagram of maintaining the state of skin coloration.

圖2是將作為有效成分含有由二羥丙酮和赤藻酮糖組成的混合物的皮膚著色化妝品組合物塗抹在皮膚後,實施針對皮膚著色度的感官評價的結果示意圖。 2 is a schematic diagram showing the results of sensory evaluation of skin coloration degree after applying a skin coloring cosmetic composition containing a mixture of dihydroxyacetone and erythrulose as active ingredients to the skin.

只要沒有定義為其他方式,本說明書中使用的所有技術及科學用語與本發明所屬技術領域的熟練專家能夠通常理解的意思相同。一般 來說,本說明書中使用的命名法是在本技術領域中周知的通常使用的命名法。 Unless otherwise defined, all technical and scientific terms used in this specification have the same meaning as commonly understood by a person skilled in the art to which this invention belongs. generally In general, the nomenclature used in this specification is a commonly used nomenclature known in the art.

本發明涉及含有二羥丙酮和赤藻酮糖的皮膚著色用化妝品組合物,具體地說涉及將二羥丙酮和赤藻酮糖作為有效成分含有的皮膚著色用化妝品組合物,上述二羥丙酮通過與皮膚角質層中含有的氨基酸的氨基的反應來形成褐色化合物的類黑精,上述赤藻酮糖增強二羥丙酮的皮膚著色持續效果。 The present invention relates to a cosmetic composition for skin coloring containing dihydroxyacetone and erythrulose, and more particularly, to a cosmetic composition for skin coloring containing dihydroxyacetone and erythrulose as active ingredients, wherein the dihydroxyacetone is passed through The melanoidin which reacts with the amino group of the amino acid contained in the stratum corneum of the skin to form a brown compound, and the above-mentioned erythrulose enhances the skin coloring lasting effect of dihydroxyacetone.

上述化妝品組合物可以劑型化為例如,營養霜、按摩膏、眼霜、潤膚霜類和爽膚水、乳液、潤膚乳類及撕拉類等,優選為撕拉類。對於撕拉類的情況,因特有的遮蓋力能更加有效地實現著色。例如,對於茂密的眉毛,撕拉劑型可以相對地增加化妝品組合物與皮膚接觸面積,能夠更加有效地實現皮膚著色。 The above-mentioned cosmetic compositions can be formulated into, for example, nutritional creams, massage creams, eye creams, moisturizing creams and toners, lotions, moisturizing milks, and peel-offs, preferably peel-offs. In the case of tearing, the coloring can be achieved more effectively due to its unique covering power. For example, for lush eyebrows, the tear-off dosage form can relatively increase the contact area between the cosmetic composition and the skin, and can more effectively achieve skin coloration.

本發明的一個實施例中,在皮膚上塗抹撕拉類劑型的情況,為了對比著色力和持續力,選定二羥丙酮和赤藻酮糖的混合比例,並且為了具有適當的皮膚著色度,調節上述混合物的皮膚塗抹(暴露)時間,之後,確認著色後經過一定時間時的著色狀態是否保持。其結果,如圖1所示,對比撕拉類劑型的皮膚著色力(膚色的深淺)時,可以確認二羥丙酮的濃度越高,皮膚的褐色色彩越深。另一方面,可以確認皮膚著色持續力(對皮膚的著色效果長時間保持的程度)相對於劑型例2,二羥丙酮和赤藻酮糖的混合重量比為7:3的劑型例1最優異。 In one embodiment of the present invention, in the case of applying a peel-off dosage form on the skin, in order to compare the coloring power and the lasting power, the mixing ratio of dihydroxyacetone and erythrulose is selected, and in order to have an appropriate skin coloring degree, adjusting After the skin application (exposure) time of the above-mentioned mixture, it was confirmed whether or not the coloring state was maintained after a certain period of time after coloring. As a result, as shown in FIG. 1 , when the skin coloring power (skin tone) of the peel-off dosage forms was compared, it was confirmed that the higher the concentration of dihydroxyacetone, the darker the skin became. On the other hand, it was confirmed that the formulation example 1 in which the mixing weight ratio of dihydroxyacetone and erythrulose was 7:3 was the most excellent compared to the formulation example 2 in terms of the skin coloring sustainability (the extent to which the coloring effect on the skin is maintained for a long time) .

本發明的另一實施例中,針對由二羥丙酮和赤藻酮糖組成的混合物的皮膚著色度實施了感官評價。其結果,如圖2所示,可以確認相對 於單獨含有二羥丙酮或赤藻酮糖的對比劑型例1和對比劑型例2,以7:3的重量比混合二羥丙酮和赤藻酮糖的劑型例1顯示最優異的感官效果。 In another example of the present invention, a sensory evaluation was carried out on the skin coloration of a mixture consisting of dihydroxyacetone and erythrulose. As a result, as shown in Fig. 2, it was confirmed that the relative Among the comparative formulation examples 1 and 2 containing dihydroxyacetone or erythrulose alone, the formulation example 1 in which dihydroxyacetone and erythrulose were mixed in a weight ratio of 7:3 showed the most excellent sensory effect.

因此,本發明的一個觀點涉及作為有效成分含有由二羥丙酮和赤藻酮糖組成的混合物的皮膚著色用化妝品組合物。 Therefore, one aspect of the present invention relates to a cosmetic composition for skin coloring containing a mixture of dihydroxyacetone and erythrulose as active ingredients.

本發明中,上述混合物的含量優選為相對於組合物總重量的0.1~15重量%,更優選為1.0~10重量%。此時,上述混合物可以以重量為標準,將二羥丙酮和赤藻酮糖以10~4:1~5比例混合,優選為7~5:3~5,最優選為7:3。 In the present invention, the content of the mixture is preferably 0.1 to 15% by weight, more preferably 1.0 to 10% by weight, based on the total weight of the composition. At this time, the above mixture can be based on weight, and dihydroxyacetone and erythrulose can be mixed in a ratio of 10~4:1~5, preferably 7~5:3~5, most preferably 7:3.

在這裡,在上述組合物中的二羥丙酮的含量不足0.1重量%時,不能得到所需的皮膚著色效果(皮膚著色力),當含量為10重量%以下時,在細胞毒性及劑型穩定性方面沒有問題。 Here, when the content of dihydroxyacetone in the above-mentioned composition is less than 0.1% by weight, the desired skin coloring effect (skin coloring power) cannot be obtained, and when the content is 10% by weight or less, cytotoxicity and dosage form stability There's no problem with that.

另外,在上述組合物中的赤藻酮糖的含量不足0.1重量%時,不能得到所需的皮膚著色效果(皮膚著色力),當含量為5重量%以下時,在細胞毒性及劑型穩定性方面沒有問題。 In addition, when the content of erythrulose in the above-mentioned composition is less than 0.1% by weight, the desired skin coloring effect (skin coloring power) cannot be obtained, and when the content is 5% by weight or less, cytotoxicity and dosage form stability There's no problem with that.

本發明中,上述組合物可以進一步含有薄膜形成劑和醇,上述薄膜形成劑可以為選自由聚乙烯醇(polyvinyl alcohol,PVA)、聚乙酸乙烯酯(polyvinyl acetate,PVAc)、以及丙烯酸酯共聚物(acrylates copolymer)組成的群中至少一種,但並不限定於此。 In the present invention, the composition may further contain a film-forming agent and alcohol, and the film-forming agent may be selected from polyvinyl alcohol (PVA), polyvinyl acetate (PVAc), and acrylate copolymers (acrylates copolymer) at least one in the group, but not limited to this.

本發明中,上述薄膜形成劑為聚乙烯醇時,在上述組合物中的其含量可以為10~15重量%;而上述醇為乙醇時,在上述組合物中的其含量可為8~12重量%。 In the present invention, when the above-mentioned film-forming agent is polyvinyl alcohol, its content in the above-mentioned composition can be 10-15% by weight; and when the above-mentioned alcohol is ethanol, its content in the above-mentioned composition can be 8-12% by weight. weight%.

本發明中,將上述組合物塗抹在皮膚後乾燥,且將形成的膜除去時,在皮膚角質層就會沉積有色彩,使皮膚著色。 In the present invention, when the above-mentioned composition is applied to the skin, dried, and the formed film is removed, color is deposited on the stratum corneum of the skin, and the skin is colored.

本發明中,將上述撕拉劑型與其他劑型對比時,不僅有效著色于對於選自由頭皮、下巴、腋窩、鬢角、臉頰、眉毛、以及全身的具有毛根和毛囊的表皮組成的至少一處皮膚,且並不限定於此,而且能有效著色於對於包括人類的哺乳類身體的任意毛髮或絨毛位置的皮膚,例如頭髮、眉毛、睫毛、鬍鬚、下巴鬍子、胸毛、背毛、手臂毛、腿毛、生殖器毛、鼻毛、或耳毛位置的皮膚條件。 In the present invention, when the above-mentioned tear formulation is compared with other formulations, not only is it effectively colored on at least one skin selected from the scalp, chin, armpit, sideburns, cheeks, eyebrows, and epidermis with hair roots and hair follicles of the whole body, It is not limited to this, and can be effectively colored on the skin of any hair or down position on the mammalian body including humans, such as hair, eyebrows, eyelashes, beards, chin beards, chest hair, back hair, arm hair, leg hair, Skin conditions where genital hair, nose hair, or ear hair are located.

本發明中,上述組合物能夠增強皮膚著色力和皮膚著色持續力,但並不限定於此。 In the present invention, the above-mentioned composition can enhance skin coloring power and skin coloring lasting power, but is not limited to this.

上述皮膚著色力顯示在皮膚著色的色彩強度(膚色的深淺),皮膚著色持續力是指著色於皮膚的色彩保持時間程度。 The above-mentioned skin coloring power shows the color intensity (skin tone) of skin coloring, and the skin coloring lasting power refers to the degree of the color retention time of the coloring on the skin.

本發明中,上述組合物可以用於紋身眼妝,但並不限定於此。 In the present invention, the above-mentioned composition can be used for tattoo eye makeup, but is not limited thereto.

本發明中,上述組合物可以用於眉妝,但並不限定於此。 In the present invention, the above-mentioned composition can be used for eyebrow makeup, but is not limited to this.

本發明中,上述組合物的劑型沒有特別限定,根據所需目的而適當選擇。例如,可以製備成選自由柔膚水(爽膚水及乳液)、營養化妝水、精華素、營養霜、按摩膏、面膜、凝膠、精華液、眼霜、眼部精華、潔面霜、洗面乳、卸妝液、面膜、散粉、潤膚乳、潤膚霜、護膚油、護膚精華組成的群中任意一種劑型。 In the present invention, the dosage form of the above-mentioned composition is not particularly limited, and is appropriately selected according to the intended purpose. For example, it can be prepared to be selected from the group consisting of toner (toner and lotion), nutritional lotion, serum, nutritional cream, massage cream, mask, gel, serum, eye cream, eye serum, facial cleanser, facial cleanser, makeup remover It can be any dosage form in the group consisting of liquid, mask, loose powder, body lotion, body cream, skin care oil, and skin care essence.

本發明的另一觀點涉及利用上述皮膚著色用化妝品組合物製備的化妝品。 Another aspect of the present invention relates to a cosmetic prepared using the above-mentioned cosmetic composition for skin coloring.

下面通過實施例進一步詳細說明本發明。這些實施例只是為了舉例說明本發明,對於本領域具有通常知識的人員,能夠自然清楚本發明的範圍並不限定於這些實施例。 The present invention will be described in further detail below through examples. These examples are only for illustrating the present invention, and it is obvious to those having ordinary knowledge in the art that the scope of the present invention is not limited to these examples.

本發明的含有二羥丙酮和赤藻酮糖的化妝品組合物並不限定於3~4個劑型例,可以由多種劑型產品化(化妝品),根據需要實現的產品的性能、費用、以及其他條件,可以以適當比例混合二羥丙酮和赤藻酮糖,由此控制皮膚著色力和皮膚著色持續力。 The cosmetic composition containing dihydroxyacetone and erythrulose of the present invention is not limited to 3 to 4 dosage forms, and can be produced in a variety of dosage forms (cosmetics), depending on the performance, cost, and other conditions of the product. , dihydroxyacetone and erythrulose can be mixed in an appropriate ratio, thereby controlling the skin coloring power and skin coloring sustainability.

製備例:製備撕拉類劑型。 Preparation Example: Preparation of tear-off dosage forms.

以下述表1的組成,製備撕拉類劑型例1~2和對比劑型例1~2。 With the composition of the following Table 1, the tear-off dosage forms examples 1-2 and the comparative dosage forms examples 1-2 were prepared.

Figure 106132954-A0305-02-0009-2
Figure 106132954-A0305-02-0009-2

有報告指出,二羥丙酮(Merk公司,德國)的含量為10重量%以下時,沒有細胞毒性;赤藻酮糖(Pentapharm公司,瑞士)的含量為5重量%以下時,沒有細胞毒性,因此,在這裡考慮到這些情況,為了增強皮膚著色效果(著色力、著色持續力、著色均勻性),以適當含量混合二羥丙酮和赤藻酮糖,製備成撕拉類劑型。 It has been reported that when the content of dihydroxyacetone (Merk, Germany) is 10 wt% or less, there is no cytotoxicity; when the content of erythrulose (Pentapharm, Switzerland) is 5 wt% or less, there is no cytotoxicity, so , In consideration of these circumstances, in order to enhance the skin coloring effect (coloring power, coloring sustainability, coloring uniformity), dihydroxyacetone and erythrulose are mixed with appropriate content to prepare a tear-off type dosage form.

另外,上述劑型例1~2或對比劑型例1~2進一步含有作為薄膜形成劑的聚乙烯醇(polyvinyl alcohol,PVA)和作為劑型的乾燥速度調節用成分的乙醇。 In addition, the above-mentioned dosage form examples 1 to 2 or comparative dosage form examples 1 to 2 further contain polyvinyl alcohol (PVA) as a film-forming agent and ethanol as a component for adjusting the drying rate of the dosage form.

實施例1:由二羥丙酮和赤藻酮糖組成的混合物的皮膚著色功能驗證。 Example 1: Verification of skin coloring function of a mixture consisting of dihydroxyacetone and erythrulose.

將劑型例1~2或對比劑型例1~2的撕拉類劑型塗抹於皮膚3小時(或7小時),撕拉後對塗抹過的皮膚部位用水洗淨,之後將塗抹過上述劑型的皮膚部位在一天及九天經過後的時間點上進行拍攝,對比皮膚是否保持著色狀態(皮膚著色持續力)。 Apply the tear-off formulations of formulation examples 1 to 2 or comparative formulation examples 1 to 2 on the skin for 3 hours (or 7 hours), wash the smeared skin with water after tearing, and then apply the above formulations to the skin. The site was photographed at time points after one day and nine days to compare whether the skin remained pigmented (skin pigmentation persistence).

其結果,如圖1所示,對比撕拉類劑型的皮膚著色力(膚色的深淺)時,可以確認二羥丙酮的濃度越高,皮膚的褐色色彩越濃。 As a result, as shown in FIG. 1 , when the skin coloring power (skin tone) of the peel-off dosage forms was compared, it was confirmed that the higher the concentration of dihydroxyacetone, the darker the skin became.

另一方面,可以確認相對於劑型例2,以7:3混合二羥丙酮和赤藻酮糖的劑型例1具有最優異的皮膚著色持續力(對皮膚的著色效果長時間保持的程度)。 On the other hand, it was confirmed that Formulation Example 1 in which dihydroxyacetone and erythrulose were mixed at a ratio of 7:3 had the most excellent skin coloring lasting power (the extent to which the skin coloring effect was maintained for a long time) compared to Formulation Example 2.

實施例2:由二羥丙酮和赤藻酮糖組成的混合物的皮膚著色度的感官評價。 Example 2: Sensory evaluation of skin coloration of a mixture consisting of dihydroxyacetone and erythrulose.

為了對比本發明的化妝效果,以20名參與者為對象,將對比劑型例1、對比劑型例2、以及劑型例1塗抹在手腕皮膚(優選為眉毛)後,以下述指標為標準進行感官檢查。也就是,將皮膚的色彩強度(color intensity)、自然膚色(natural-looking skin tone)、裸妝感(less streaking)、氣味小(less odor)、均勻膚色(homogenous skin tone)、迅速著色結果(fast 'coloring' result)、以及皮膚乾燥度(skin drying)作為標準指標,由5分尺度進行評價(5分:非常優秀;4分:比較優秀;3分:一般;2分:差;1分:非常差)。 In order to compare the cosmetic effect of the present invention, 20 participants were used as objects to apply the comparative formulation example 1, the comparative formulation example 2, and the formulation example 1 to the wrist skin (preferably eyebrows), and the following indexes were used as the standard to conduct a sensory inspection. . That is, color intensity of skin, natural-looking skin tone, less streaking, less odor, homogenous skin tone, rapid coloring results ( fast 'coloring' result), and skin drying as standard indicators, which were evaluated on a 5-point scale (5 points: very good; 4 points: relatively good; 3 points: fair; 2 points: poor; 1 point :very bad).

其結果,如圖2所示,可以確認相對於單獨含有二羥丙酮或赤藻酮糖的對比劑型例1和對比劑型例2,以7:3混合二羥丙酮和赤藻酮糖的劑型例1顯示最優異的感官效果。 As a result, as shown in FIG. 2 , it was confirmed that a dosage form example in which dihydroxyacetone and erythrulose were mixed at a ratio of 7:3 to the comparative dosage form example 1 and comparative dosage form example 2 containing dihydroxyacetone or erythrulose alone 1 shows the most excellent sensory effect.

如上詳細說明本發明內容的特徵部分,對於具有本領域的通常知識的人員,能明確認識到這些具體技術只不過是優選實施方式,且本 發明的範圍並不限定於此。因此本發明的實質性範圍可以定義為申請專利範圍及其等價物。 The characteristic parts of the present invention are described in detail above, and those with ordinary knowledge in the art can clearly recognize that these specific techniques are only preferred embodiments, and the present invention The scope of the invention is not limited to this. Accordingly, the substantial scope of the present invention may be defined as the claimed scope and equivalents thereof.

Claims (8)

一種化妝品組合物,其特徵在於,該組合物為改善皮膚著色的均勻性和持久性的撕拉劑型化妝品組合物,作為有效成分含有二羥丙酮(dihydroxyacetone,DHA)和赤藻酮糖(erythrulose)的混合物、薄膜形成劑以及乙醇,其中相對於所述化妝品組合物的總重量,所述二羥丙酮和赤藻酮糖的混合物的含量為10~15重量%,所述二羥丙酮、赤藻酮糖、薄膜形成劑以及乙醇的重量比為7~5:3~5:12:10,所述薄膜形成劑為聚乙烯醇(polyvinyl alcohol,PVA)。 A cosmetic composition, characterized in that the composition is a peel-off cosmetic composition for improving the uniformity and persistence of skin coloration, and contains dihydroxyacetone (DHA) and erythrulose as active ingredients The mixture, film-forming agent and ethanol, wherein relative to the total weight of the cosmetic composition, the content of the mixture of dihydroxyacetone and erythrulose is 10 to 15% by weight, and the dihydroxyacetone, erythritol The weight ratio of ketose, film-forming agent and ethanol is 7-5:3-5:12:10, and the film-forming agent is polyvinyl alcohol (PVA). 根據請求項1所述的化妝品組合物,其中,所述二羥丙酮和赤藻酮糖的混合物的含量為相對於所述化妝品組合物的總重量的10重量%。 The cosmetic composition according to claim 1, wherein the content of the mixture of dihydroxyacetone and erythrulose is 10% by weight relative to the total weight of the cosmetic composition. 根據請求項1所述的化妝品組合物,其中,所述二羥丙酮、赤藻酮糖、薄膜形成劑以及乙醇的重量比為7:3:12:10。 The cosmetic composition according to claim 1, wherein the weight ratio of the dihydroxyacetone, erythrulose, film-forming agent, and ethanol is 7:3:12:10. 根據請求項1所述的化妝品組合物,其中,所述化妝品組合物在使用於皮膚時具有自然膚色(natural-looking skin tone)。 The cosmetic composition according to claim 1, wherein the cosmetic composition has a natural-looking skin tone when applied to the skin. 根據請求項1所述的化妝品組合物,其中,所述皮膚著色為在有毛髮的皮膚的局部部位著色。 The cosmetic composition according to claim 1, wherein the skin coloring is coloring a local part of skin with hair. 根據請求項5所述的化妝品組合物,其中,所述毛髮為選自頭髮、眉毛、睫毛、下巴鬍子、鬍鬚、頰毛、胸毛、背毛、 手臂毛、腋毛、腿毛、生殖器毛、鼻毛以及耳毛組成的群中的至少一種。 The cosmetic composition according to claim 5, wherein the hair is selected from the group consisting of hair, eyebrows, eyelashes, chin beard, beard, cheek hair, chest hair, back hair, At least one of the group consisting of arm hair, armpit hair, leg hair, genital hair, nose hair and ear hair. 根據請求項6所述的化妝品組合物,其中,所述化妝品組合物用於眉毛或睫毛的化妝。 The cosmetic composition according to claim 6, wherein the cosmetic composition is used for makeup of eyebrows or eyelashes. 一種將由二羥丙酮、赤藻酮糖、薄膜形成劑以及乙醇組成的混合物在製備改善皮膚著色的均勻性和持久性的撕拉劑型化妝品組合物中的用途,其特徵在於:相對於所述化妝品組合物的總重量,所述二羥丙酮和赤藻酮糖的含量為10~15重量%,所述二羥丙酮、赤藻酮糖、薄膜形成劑以及乙醇的重量比為7~5:3~5:12:10,所述薄膜形成劑為聚乙烯醇。 A use of a mixture consisting of dihydroxyacetone, erythrulose, a film-forming agent and ethanol in the preparation of a pull-off cosmetic composition for improving the uniformity and persistence of skin coloration, characterized in that: relative to the cosmetic The total weight of the composition, the content of the dihydroxyacetone and erythrulose is 10 to 15% by weight, and the weight ratio of the dihydroxyacetone, erythrulose, film-forming agent and ethanol is 7 to 5:3 ~5:12:10, the film former is polyvinyl alcohol.
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US20050238595A1 (en) * 2004-04-21 2005-10-27 Qing Stella Personal care compositions that deposit sunless tanning benefit agents
US20080193405A1 (en) * 2005-01-28 2008-08-14 Basf Aktiengesellschaft Use of a Water-In-Water Emulsion Polymers in the Form of a Thickener for Cosmetic Preparations

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