TWI756746B - Virus collection assembly, virus storage device and virus collection method - Google Patents
Virus collection assembly, virus storage device and virus collection method Download PDFInfo
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- TWI756746B TWI756746B TW109124553A TW109124553A TWI756746B TW I756746 B TWI756746 B TW I756746B TW 109124553 A TW109124553 A TW 109124553A TW 109124553 A TW109124553 A TW 109124553A TW I756746 B TWI756746 B TW I756746B
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本發明是有關於一種病毒收集技術,且特別是有關於一種病毒收集總成、一種病毒儲存裝置及一種病毒收集方法。The present invention relates to a virus collection technology, and in particular, to a virus collection assembly, a virus storage device and a virus collection method.
在醫學上,某些疾病的發生通常與微生物(例如病毒、細菌等)有關。由於微生物無法單從肉眼觀察,所以需要從受試者取得測試樣本,並對測試樣本進行測試,以得知測試樣本為何種微生物。如此才能給予受試者適當的治療或處置。In medicine, the occurrence of certain diseases is usually related to microorganisms (such as viruses, bacteria, etc.). Since microorganisms cannot be observed with the naked eye, it is necessary to obtain a test sample from the subject and test the test sample to know what kind of microorganism the test sample is. Only then can the subject be given appropriate treatment or treatment.
本發明提供一種病毒收集總成,用於收集及儲存病毒。The present invention provides a virus collection assembly for collecting and storing viruses.
本發明提供一種病毒儲存裝置,用於儲存已收集的病毒。The present invention provides a virus storage device for storing collected viruses.
本發明提供一種病毒收集方法,用於收集及儲存病毒。The present invention provides a virus collection method for collecting and storing viruses.
本發明的病毒收集總成包括一吹氣嘴、一濾片固定器、一第一蓋體及一第二蓋體。吹氣嘴適於連接一氣體收集袋。濾片固定器可拆卸地連接至吹氣嘴並適於固定一濾片。濾片固定器包括一第一固定套筒及一第二固定套筒。第二固定套筒在一軸線上與第一固定套筒彼此套合,並與第一固定套筒夾持濾片。第一蓋體可拆卸地連接至濾片固定器。第二蓋體可拆卸地連接至第一蓋體。彼此連接的第一蓋體與第二蓋體容納濾片固定器及其所固定的濾片。The virus collection assembly of the present invention includes a blowing nozzle, a filter holder, a first cover and a second cover. The blowing nozzle is adapted to be connected to a gas collection bag. The filter holder is detachably connected to the blowing nozzle and is adapted to hold a filter. The filter holder includes a first fixing sleeve and a second fixing sleeve. The second fixing sleeve is sleeved with the first fixing sleeve on an axis, and clamps the filter disc with the first fixing sleeve. The first cover is detachably connected to the filter holder. The second cover is detachably connected to the first cover. The first cover body and the second cover body, which are connected to each other, accommodate the filter holder and the filter to which it is fixed.
本發明的病毒儲存裝置包括一濾片固定器、一第一蓋體及一第二蓋體。濾片固定器適於固定一濾片。第一蓋體可拆卸地連接至濾片固定器。第二蓋體可拆卸地連接至第一蓋體。彼此連接的第一蓋體與第二蓋體容納濾片固定器及其所固定的濾片。The virus storage device of the present invention includes a filter holder, a first cover and a second cover. The filter holder is suitable for fixing a filter. The first cover is detachably connected to the filter holder. The second cover is detachably connected to the first cover. The first cover body and the second cover body, which are connected to each other, accommodate the filter holder and the filter to which it is fixed.
本發明的病毒收集方法包括下列步驟。經由一吹氣嘴接收來自受試者所吹出的氣體至與吹氣嘴連通的一氣體收集袋。在氣體收集袋收集受試者所吹出的氣體之後,將一濾片固定器安裝至吹氣嘴。經由吹氣嘴抽出收集於氣體收集袋內的氣體,使得收集於氣體收集袋內的氣體流過濾片固定器所固定的一濾片。將一第一蓋體可拆卸地連接至濾片固定器。在將第一蓋體可拆卸地連接至濾片固定器之後,經由第一蓋體將濾片固定器及其所固定的濾片拆卸自吹氣嘴。將第一蓋體連接至一第二蓋體,使得濾片固定器及其所固定的濾片收容在第一蓋體與第二蓋體內。The virus collection method of the present invention includes the following steps. Air blown from the subject is received via an insufflation nozzle to a gas collection bag in communication with the insufflation nozzle. After the gas collection bag collected the gas blown by the subject, a filter holder was attached to the insufflation nozzle. The gas collected in the gas collection bag is drawn out through the blowing nozzle, so that the gas collected in the gas collection bag flows through a filter piece fixed by the filter piece holder. A first cover is detachably connected to the filter holder. After the first cover is detachably connected to the filter holder, the filter holder and the fixed filter are detached from the blowing nozzle via the first cover. The first cover is connected to a second cover, so that the filter holder and the fixed filter are accommodated in the first cover and the second cover.
基於上述,在本發明中,藉由吹氣的方式收集來自受試者可能含有病毒等微生物樣本的氣體,並藉由抽氣的方式將氣體中可能存在病毒等微生物樣本保留在濾片中。此外,更藉由第一蓋體將濾片固定器及其所夾持的濾片取出,並藉由彼此組裝在一起的第一蓋體與第二蓋體來儲存濾片固定器及其所夾持的濾片,以利於後續的病毒等微生物樣本的保存、運送、以及測試作業。Based on the above, in the present invention, the gas from the subject that may contain microbial samples such as viruses is collected by blowing air, and the microbial samples that may contain viruses and other microorganisms in the gas are retained in the filter by suction. In addition, the filter holder and its clamped filter are taken out through the first cover, and the filter holder and the filter holder are stored by the first cover and the second cover assembled with each other. The clamped filter is convenient for subsequent preservation, transportation, and testing of microbial samples such as viruses.
請參考圖1A及圖1B,在本實施例中,病毒收集總成100包括一吹氣嘴110、一濾片固定器120、一第一蓋體131及一第二蓋體132。吹氣嘴110適於連接一氣體收集袋50。濾片固定器120可拆卸地連接至吹氣嘴110並適於固定一濾片60(例如,但不限於,熔噴不織布)。第一蓋體131可拆卸地連接至濾片固定器120。第二蓋體132可拆卸地連接至第一蓋體131。彼此連接的第一蓋體131與第二蓋體132容納濾片固定器120及其所固定的濾片60。Referring to FIGS. 1A and 1B , in this embodiment, the
請參考圖1A及圖1B,在本實施例中,吹氣嘴110可包括一本體111、一連接膠圈112及一密合膠圈113。連接膠圈112位於本體111的一端,以適於連接氣體收集袋50的一通氣管52。密合膠圈113位於本體111的外側,以使吹氣嘴110的本體111在被抽氣時與外界的抽氣泵浦吸嘴(未繪示)密合。在另一實施例中,氣體收集袋50及吹氣嘴110可以是固定連接而不分離的。Referring to FIGS. 1A and 1B , in this embodiment, the blowing
請參考圖1A及圖1B,在本實施例中,濾片固定器120可包括一第一固定套筒121及一第二固定套筒122。第二固定套筒122在一軸線A上與第一固定套筒121彼此套合,並與第一固定套筒121夾持濾片60。此外,在將第二固定套筒122與第一固定套筒121彼此套合之前,可藉由一雙面膠片62,將濾片60預先黏貼至第二固定套筒122的一端。Referring to FIGS. 1A and 1B , in this embodiment, the
請參考圖1A及圖1B,在本實施例中,吹氣嘴110的本體111可具有一或多個第一閂部L1(例如閂孔)。第一固定套筒121可具有一或多個第二閂部L2(例如閂件),第一固定套筒121在軸線A上與吹氣嘴110的本體111彼此套合,且第二閂部L2與第一閂部L1的扣合限制第一固定套筒121相對於吹氣嘴110的本體111在軸線A上的平移。簡言之,藉由第一閂部L1與第二閂部L2之間的閂接,將第一固定套筒121可拆卸地連接至吹氣嘴110的本體111。Referring to FIG. 1A and FIG. 1B , in this embodiment, the
請參考圖1A及圖1B,在本實施例中,第一蓋體131可具有一第一內套筒131a及一第一配接部F1。第二固定套筒122可具有一第二配接部F2。第二固定套筒122與第一內套筒131a彼此套合。第一配接部F1與第二配接部F2的配合限制第一固定套筒121相對於第一內套筒131a在軸線A上的平移。此外,第二固定套筒122與第一內套筒131a彼此在結構上略微干涉配合(即緊配合),以將第一蓋體131與濾片固定器120可拆卸地連接。Referring to FIG. 1A and FIG. 1B , in this embodiment, the
請參考圖1A及圖1B,在本實施例中,第一固定套筒121可具有一第一嵌合部E1(例如環狀凹溝)。第二固定套筒122可具有一第二嵌合部E2(例如環狀凸肋)。第一嵌合部E1與第二嵌合部E2的嵌合限制第二固定套筒122相對於第一固定套筒121在軸線A上的平移,如圖3所示。因此,藉由第一嵌合部E1與第二嵌合部E2之間的嵌合,將第二固定套筒122可拆列地固定至第一固定套筒121。Referring to FIG. 1A and FIG. 1B , in this embodiment, the
請參考圖1A、圖1B及圖3,在本實施例中,第一固定套筒121具有一或多個第一導引部G1(例如導引凸肋)。第二固定套筒122可具有一或多個第二導引部G2(例如導引凹溝)。第一導引部G1與第二導引部G2的配合限制第二固定套筒122相對於第一固定套筒121在軸線A上的旋轉。因此,藉由第一嵌合部E1與第二嵌合部E2之間的嵌合,第二固定套筒122被可拆卸地固定至第一固定套筒121。Referring to FIGS. 1A , 1B and 3 , in this embodiment, the
請參考圖1A、圖1B及圖3,在本實施例中,第二蓋體132具有一第二內套筒132a。第一固定套筒121與第二內套筒132a彼此套合,以將濾片固定器120定位在第二蓋體132內。Please refer to FIG. 1A , FIG. 1B and FIG. 3 , in this embodiment, the
請參考圖1A、圖1B及圖3,在本實施例中,第一蓋體131具有一第一螺紋S1(例如內螺紋)。第二蓋體132具有一第二螺紋S2,且第一螺紋S1與第二螺紋S2的嚙合將第一蓋體131連接至第二蓋體132。Please refer to FIG. 1A , FIG. 1B and FIG. 3 , in this embodiment, the
請參考圖1A、圖1B及圖3,在本實施例中,病毒收集總成100可更包括一密封膠圈133,第一蓋體131與第二蓋體132連接,密封膠圈133位於第一蓋體131與第二蓋體132之間。Please refer to FIG. 1A , FIG. 1B and FIG. 3 , in this embodiment, the
請參考圖1A、圖1B及圖3,在本實施例中,上述的濾片固定器120、第一蓋體131及第二蓋體132可構成病毒儲存裝置100a。此外,病毒儲存裝置100a也可包括其他構件,例如上述的密封膠圈133等。換言之,上述病毒收集總成100包括吹氣嘴110及病毒儲存裝置100a。Please refer to FIG. 1A , FIG. 1B and FIG. 3 , in this embodiment, the
以下配合圖2A至圖2K來說明本發明的一實施例的一種病毒收集方法,其所採用的構件可見於圖1A及圖1B所揭露的病毒收集總成100。病毒收集方法包括下列步驟。A virus collection method according to an embodiment of the present invention is described below with reference to FIGS. 2A to 2K . The components used in the virus collection method can be seen in the
請參考圖2A,可藉由一密封蓋70來封閉吹氣嘴110的一端。在其他實施例中,也可沒有密封蓋70。Referring to FIG. 2A , one end of the blowing
請參考圖2B,在密封蓋70從吹氣嘴110移離之後,並經由吹氣嘴110接收來自受試者所吹出的氣體至與吹氣嘴110連通的氣體收集袋50。Referring to FIG. 2B , after the sealing
請參考圖2C,在氣體收集袋50收集受試者所吹出的氣體之後,將一濾片固定器120安裝至吹氣嘴110。具體而言,如圖2C所示,可將濾片固定器120可拆卸地連接至第一蓋體131。接著,如圖2D所示,經由第一蓋體131將濾片固定器120可拆卸地連接至吹氣嘴110。之後,如圖2E所示,將第一蓋體131拆卸自濾片固定器120。Referring to FIG. 2C , after the gas blown by the subject is collected by the
請參考圖2F,經由吹氣嘴110抽出(例如利用抽氣泵浦)收集於氣體收集袋50內的氣體,使得收集於氣體收集袋50內的氣體流過濾片固定器120所固定的一濾片60,如圖1A所示。因此,流經濾片60的氣體中的病毒等微生物將停留在濾片60上。Referring to FIG. 2F , the gas collected in the
在本實施例中,可經由濾片固定器120的第一固定套筒121及第二固定套筒122來夾持濾片60。此外,可藉由一雙面膠片62,將濾片60預先黏貼至第二固定套筒122的一端。因此,在第一固定套筒121及第二固定套筒122彼此套合的過程中,雙面膠片62可確保濾片60的位置不會偏離。In this embodiment, the
請參考圖2G,將一第一蓋體131可拆卸地連接至濾片固定器120。具體而言,如圖2G所示,將第一蓋體131在軸線A上與濾片固定器120彼此配合。接著,如圖2H所示,相對於吹氣嘴110旋轉第一蓋體131一特定角度,以解除濾片固定器120與吹氣嘴110之間的可拆卸連接(例如第一閂部L1及第二閂部L2之間的扣合)。在本實施例中,第一蓋體131與濾片固定器120彼此在結構上略微干涉配合,即緊配合。因此,當濾片固定器120與吹氣嘴110未建立可拆卸連接時,將第一蓋體131移離吹氣嘴110可連帶將濾片固定器120移離吹氣嘴110。Referring to FIG. 2G , a
請參考圖2I,在將第一蓋體131可拆卸地連接至濾片固定器120之後,經由第一蓋體131將濾片固定器120及其所固定的濾片60拆卸自吹氣嘴110。Referring to FIG. 2I , after the
請參考圖2J,將第一蓋體131連接至一第二蓋體132,使得濾片固定器120及其所固定的濾片60收容在第一蓋體131與第二蓋體132內。具體而言,如圖2J所示,可將第一蓋體131連同其上的濾片固定器120朝向第二蓋體132移動。接著,如圖2K所示,經由第一蓋體131的第一螺紋S1及第二蓋體132的第二螺紋S2的嚙合將第一蓋體131可拆卸地連接至第二蓋體132。Referring to FIG. 2J , the
綜上所述,在本發明中,藉由吹氣的方式收集來自受試者可能含有病毒等微生物樣本的氣體,並藉由抽氣的方式將氣體中可能存在病毒等微生物樣本保留在濾片中。此外,更藉由第一蓋體將濾片固定器及其所夾持的濾片取出,並藉由彼此組裝在一起的第一蓋體與第二蓋體來儲存濾片固定器及其所夾持的濾片,以利於後續的病毒等微生物樣本的保存、運送、以及測試作業。To sum up, in the present invention, the gas from the subject that may contain microbial samples such as viruses is collected by blowing air, and the microbial samples that may contain viruses and other microorganisms in the gas are retained on the filter by suction. middle. In addition, the filter holder and its clamped filter are taken out through the first cover, and the filter holder and the filter holder are stored by the first cover and the second cover assembled with each other. The clamped filter is convenient for subsequent preservation, transportation, and testing of microbial samples such as viruses.
50:氣體收集袋
52:通氣管
60:濾片
62:雙面膠片
70:密封蓋
100:病毒收集總成
100a:病毒儲存裝置
110:吹氣嘴
111:本體
112:連接膠圈
113:密合膠圈
120:濾片固定器
121:第一固定套筒
122:第二固定套筒
131:第一蓋體
131a:第一內套筒
132:第二蓋體
132a:第二內套筒
133:密封膠圈
A:軸線
E1:第一嵌合部
E2:第二嵌合部
F1:第一配接部
F2:第二配接部
G1:第一導引部
G2:第二導引部
L1:第一閂部
L2:第二閂部
S1:第一螺紋
S2:第二螺紋
50: Gas collection bag
52: Snorkel
60: Filter
62: Double-sided film
70: sealing cover
100:
圖1A是本發明的一實施例的一種病毒收集總成及氣體收集袋的分解圖。 圖1B是圖1的病毒收集總成及氣體收集袋的另一分解圖。 圖2A至圖2K繪示本發明的一實施例的一種病毒收集方法。 圖3繪示圖2K的病毒儲存裝置的剖視圖。 1A is an exploded view of a virus collection assembly and a gas collection bag according to an embodiment of the present invention. FIG. 1B is another exploded view of the virus collection assembly and gas collection bag of FIG. 1 . 2A to 2K illustrate a virus collection method according to an embodiment of the present invention. 3 is a cross-sectional view of the virus storage device of FIG. 2K.
50:氣體收集袋
52:通氣管
60:濾片
62:雙面膠片
70:密封蓋
100:病毒收集總成
110:吹氣嘴
111:本體
112:連接膠圈
113:密合膠圈
120:濾片固定器
121:第一固定套筒
122:第二固定套筒
131:第一蓋體
132:第二蓋體
132a:第二內套筒
133:密封膠圈
A:軸線
E2:第二嵌合部
F2:第二配接部
G1:第一導引部
G2:第二導引部
L1:第一閂部
L2:第二閂部
S2:第二螺紋
50: Gas collection bag
52: Snorkel
60: Filter
62: Double-sided film
70: sealing cover
100: Virus Collection Assembly
110: blowing mouth
111: Ontology
112: Connect the rubber ring
113: Sealing rubber ring
120: Filter holder
121: The first fixed sleeve
122: Second fixed sleeve
131: The first cover
132:
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TW201024421A (en) * | 2008-12-24 | 2010-07-01 | Univ Kaohsiung Medical | Quantitative sampler of exhaled pathogens and quantitative analysis method using the same |
CN106085830A (en) * | 2016-08-30 | 2016-11-09 | 浙江省疾病预防控制中心 | Pathogenic microorganism collection device in air |
WO2018210128A1 (en) * | 2017-05-16 | 2018-11-22 | 上海德具生物科技有限公司 | Method for on-line collection and on-line automatic detection of bacteria or viruses in air |
US20200122134A1 (en) * | 2018-10-19 | 2020-04-23 | Vanderbilt University | Efficient capture of magnetic and paramagnetic carriers of biomarkers from a flowing system |
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TW201024421A (en) * | 2008-12-24 | 2010-07-01 | Univ Kaohsiung Medical | Quantitative sampler of exhaled pathogens and quantitative analysis method using the same |
CN106085830A (en) * | 2016-08-30 | 2016-11-09 | 浙江省疾病预防控制中心 | Pathogenic microorganism collection device in air |
WO2018210128A1 (en) * | 2017-05-16 | 2018-11-22 | 上海德具生物科技有限公司 | Method for on-line collection and on-line automatic detection of bacteria or viruses in air |
US20200122134A1 (en) * | 2018-10-19 | 2020-04-23 | Vanderbilt University | Efficient capture of magnetic and paramagnetic carriers of biomarkers from a flowing system |
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