CN114795306A

CN114795306A - Tissue sample sampling device and endoscope system

Info

Publication number: CN114795306A
Application number: CN202210734544.5A
Authority: CN
Inventors: 陈东; 张瑞
Original assignee: Xinguangwei Medical Technology Suzhou Co ltd
Current assignee: Xinguangwei Medical Technology Suzhou Co ltd
Priority date: 2022-06-27
Filing date: 2022-06-27
Publication date: 2022-07-29
Anticipated expiration: 2042-06-27
Also published as: CN114795306B; WO2024001002A1

Abstract

The invention discloses a tissue sample sampling device and an endoscope system, comprising: a mounting housing for placement over an endoscope, the mounting housing including a suction inlet for docking with the endoscope and a suction outlet for docking with an external power source; the sampling piece is arranged on the mounting shell; the control piece is movably arranged on the mounting shell, and a sampling passage used for inputting the tissue sample to the sampling piece is arranged on the control piece; wherein the control has a first state and a second state, the sampling passage interfacing between the aspiration inlet and the aspiration outlet when the control is in the first state; when the control is in the second state, the sampling passage is not interfaced with the aspiration inlet and/or the aspiration outlet. The endoscope has high linkage with the endoscope, has a simple integral structure, and can effectively control a sampling passage.

Description

Tissue sample sampling device and endoscope system

Technical Field

The invention relates to the technical field of endoscopes, in particular to a tissue sample sampling device and an endoscope system.

Background

When examining a disease in a human body by an endoscope, it is often necessary to take human tissue out of the body and perform examination and test on other instruments. For example, in bronchoscopic clinical diagnosis and treatment, the suction of airway distal secretions through a bronchoscope and the suction of lavage fluid through bronchoscopic alveolar lavage are common methods for obtaining a specimen of an airway infection part.

In practice, a sampling device is typically provided that interfaces with an endoscope, and includes a suction structure and a sampling member removably attached to the suction structure, wherein a body tissue sample can be collected via the suction structure. However, in the prior art, the sampling device used in the surgical operation is often placed far away from the endoscope, and the linkage with the endoscope is insufficient, so that the sampling is not performed in the optimal sampling time period. Or the sampling device is integrated on the endoscope, but the sampling device has a complex structure and is high in manufacturing cost and process, so that the production is not facilitated.

Accordingly, there is a need for improvements in the art that overcome the deficiencies in the prior art.

Disclosure of Invention

The invention aims to provide a tissue sample sampling device and an endoscope system, which have good linkage with an endoscope and simple structure and effectively control the on-off of sampling.

The purpose of the invention is realized by the following technical scheme: a tissue sample sampling device, comprising: a mounting housing for placement over an endoscope, the mounting housing including a suction inlet for docking with the endoscope and a suction outlet for docking with an external power source; the sampling piece is arranged on the mounting shell; the control piece is movably arranged on the mounting shell, and a sampling passage used for inputting the tissue sample to the sampling piece is arranged on the control piece; wherein the control has a first state and a second state, the sampling passage interfacing between the aspiration inlet and the aspiration outlet when the control is in the first state; when the control is in the second state, the sampling passage is not interfaced with the aspiration inlet and/or the aspiration outlet.

Further, the sampling path includes: the first sampling branch comprises a first connecting port and a first sampling port; the second sampling branch comprises a second connecting port and a second sampling port; the first sampling port and the second sampling port are arranged in the sampling piece, when the control piece is in the first state, the first connecting port is communicated with the suction inlet, the second connecting port is communicated with the suction outlet, when the control piece is in the second state, the first connecting port is not communicated with the suction inlet, and the second connecting port is not communicated with the suction outlet.

Further, a liquid drainage passage is arranged on the control element, and when the control element is in the second state, the liquid drainage passage is butted between the suction inlet and the suction outlet.

Further, the control member includes: the main body part is movably connected with the mounting shell; the inserting and puncturing part is connected with the main body part and can be inserted into the sampling piece along the assembling and disassembling direction of the sampling piece; the first sampling port and the second sampling port are both located on the bayonet portion, and the main body portion can move to the first state or the second state relative to the mounting shell.

Further, the mounting housing includes a first mount, the first mount including: the first mounting part is used for connecting the main body part, and the main body part can rotate relative to the first mounting part; the second mounting part is used for connecting the sampling piece; the first installation part and the second installation part are provided with avoidance spaces, and the insertion part can stretch to the sampling part from the avoidance spaces.

Further, first installation department is equipped with first installation cavity, the suction inlet with the suction outlet all with first installation cavity intercommunication, the week side of main part with the inner wall laminating contact of first installation cavity.

Further, the tissue sample sampling device comprises a first stop structure adapted to limit movement of the body portion in the direction of its rotational axis.

Further, a sealing member is provided between the mounting case and the main body portion, the sealing member sealing a communication position of the control member and the mounting case.

Further, the second installation part is provided with a second installation cavity, and at least part of the sampling piece is detachably and fixedly contained in the second installation cavity.

Further, the tissue sample sampling device includes a second stop structure adapted to move the control member between a first limit position and a second limit position, the sampling path being in the first state when the control member is moved to the first limit position and the sampling path being in the second state when the control member is moved to the second limit position.

Further, the control member further includes a handle portion for moving the main body portion, the handle portion protruding with respect to the main body portion.

Further, the sampling member includes: a collector having a collection port; the cover body is connected with the collector; the sealing cover part is arranged on the cover body and is used for sealing the collecting port; wherein the cover part is at least partially a flexible structure which can be punctured by the inserting and puncturing part.

Further, the flexible structure is made of one of silicon rubber, fluorine rubber, butyl rubber and PTFE material, or is made of composite material made of the materials in combination.

Further, the cover sealing part comprises a rubber layer and a plastic layer, the rubber layer faces the collecting opening, and the plastic layer faces the inserting and puncturing part.

Furthermore, the sampling piece is detachably connected with the mounting shell through one or more of clamping, threaded connection, magnetic attraction and fasteners.

Further, the mounting case includes: a second mounting member removably coupled to the endoscope; and a connector which is received between the second mounting section and the first mounting section and which has an escape gap between the first mounting section and the endoscope.

Further, the present invention provides an endoscope system comprising: the aforementioned tissue sample sampling device; an endoscope, the tissue sample sampling device being disposed on the endoscope; and a suction passage provided in the endoscope and communicating with the suction inlet.

Further, still include: a duct member connected between the suction passage and the suction inlet; a suction valve connected to the suction passage and/or the duct member; wherein the suction valve has an on state and an off state, the suction valve being switched from the off state to the on state in response to a pressing operation.

Compared with the prior art, the invention has the following beneficial effects: the sampling device comprises the installation shell, the control piece and the sampling piece, wherein the installation shell is arranged on the endoscope, and the control piece and the sampling piece are both arranged on the installation shell, so that the linkage of the sampling device and the endoscope is improved, and the sampling is favorably carried out in time in the optimal sampling time period; the installation shell is provided with a suction inlet communicated with the endoscope and a suction outlet communicated with an external power source, the control piece is movably arranged on the installation shell and is provided with a sampling passage for inputting a tissue sample to the sampling piece, the control piece can be switched to a first state or a second state, the sampling passage is communicated between the suction inlet and the suction outlet in the first state, so that the tissue sample can be normally input into the sampling piece through the sampling passage, when the sampling is required to be cut off, the control piece is only required to be switched to the second state, the communication between the sampling passage and the suction inlet and/or the suction outlet is cut off, the above mode of sampling is realized, an additional on-off structure is not required to be arranged between the installation shell and the control piece, and the sampling passage can be effectively controlled while the whole structure of the sampling device is simple.

Drawings

FIG. 1 is a schematic view of the construction of an endoscope system of the present invention.

Fig. 2 is a schematic structural view of the tissue sample sampling device of the present invention.

Fig. 3 is an exploded view of fig. 2.

Fig. 4 is a cross-sectional view of the control member of fig. 2 in a first state.

Fig. 5 is a partial enlarged view of fig. 4 at a.

Fig. 6 is a cross-sectional view of the control member of fig. 2 in a second state.

Fig. 7 is a schematic cross-sectional view of a mounting housing of the present invention.

Fig. 8 is a top view of the mounting housing of the present invention.

Fig. 9 is a schematic structural diagram of a control member in the present invention.

Fig. 10 is a schematic view of the control member of the present invention in another orientation.

Fig. 11 is an exploded view of the sampling member of the present invention.

Reference numerals:

100. an endoscope; 11. a suction passage; 200. mounting a shell; 201. a suction inlet; 202. a suction outlet; 203. a second indicator; 21. a first mounting member; 211. a first mounting portion; 2111. a first mounting cavity; 2112. a second limiting part; 2113. a fourth guide surface; 2114. a limiting surface; 212. a second mounting portion; 2121. a second mounting cavity; 2122. a notch; 2123. a second arm section; 2124. a second clamping part; 22. a second mount; 23. a connector; 24. a limiting groove; 25. a limiting ring; 26. a connecting member; 300. a control member; 31. a main body portion; 31a, a first axis; 311. a first limiting part; 312. a first clamping part; 3121. a first guide surface; 3122. a second guide surface; 3123. a third guide surface; 313. a first arm section; 32. a bayonet part; 33. a handle portion; 331. a projection; 332. a first indication mark; 34. a sampling path; 341. a first sampling branch; 3411. a first connection port; 3412. a first sampling port; 342. a second sampling branch; 3421. a second connection port; 3422. a second sampling port; 35. a liquid discharge passage; 351. a third connection port; 352. a fourth connection port; 36. a holding block; 400. sampling; 41. a collector; 411. a collection port; 42. a cover body; 421. an inner cavity; 422. inserting a thorn opening; 43. a capping portion; 431. a rubber layer; 432. a plastic layer; 44. a tissue sample mixture; 45. an air section; 500. a pipe member; 600. and a suction valve.

Detailed Description

In order to make the aforementioned objects, features and advantages of the present application more comprehensible, embodiments accompanying the present application are described in detail below with reference to the accompanying drawings. It is to be understood that the specific embodiments described herein are merely illustrative of the application and are not limiting of the application. It should be further noted that, for the convenience of description, only some of the structures related to the present application are shown in the drawings, not all of the structures. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present application.

The terms "comprising" and "having," as well as any variations thereof, in this application are intended to cover non-exclusive inclusions. For example, a process, method, system, article, or apparatus that comprises a list of steps or elements is not limited to only those steps or elements listed, but may alternatively include other steps or elements not listed, or inherent to such process, method, article, or apparatus.

Reference herein to "an embodiment" means that a particular feature, structure, or characteristic described in connection with the embodiment can be included in at least one embodiment of the application. The appearances of the phrase in various places in the specification are not necessarily all referring to the same embodiment, nor are separate or alternative embodiments mutually exclusive of other embodiments. It is explicitly and implicitly understood by one skilled in the art that the embodiments described herein can be combined with other embodiments.

Referring to fig. 1, 4 and 7, a tissue sample sampling device according to a preferred embodiment of the present invention is provided on an endoscope 100 and is connected to a suction channel 11 of the endoscope 100, so that a human tissue sample flows into the sampling device through the suction channel 11 and is sampled and collected.

Further, the sampling device includes a mounting case 200, a control member 300, and a sampling member 400. The mounting case 200 is provided on the endoscope 100, and the control member 300 and the sampling member 400 are both provided on the mounting case 200. The mounting case 200 includes a suction inlet 201 for interfacing with the suction passage 11 of the endoscope 100 and a suction outlet 202 for interfacing with an external power source (not shown), which may be a suction device capable of generating a negative pressure. The control member 300 is provided with a sampling passage 34 for inputting a tissue sample to the sampling member 400. The control member 300 can move relative to the mounting shell 200 to switch to a first state or a second state, when the control member 300 is in the first state, the sampling passage 34 is butted between the suction inlet 201 and the suction outlet 202, negative pressure is generated at the suction inlet 201, and a tissue sample can enter the sampling member 400 for collection through the suction passage 11, the suction inlet 201 and the sampling passage 34 in sequence; when the control 300 is in the second state, the sampling passage 34 is not in abutment with the suction inlet 201 and/or the suction outlet 202, and the suction inlet 201 will not be able to generate a negative pressure, so that collection can be stopped.

In the invention, the installation shell 200 is arranged on the endoscope 100, and the control element 300 and the sampling element 400 are both arranged on the installation shell 200, thereby improving the linkage of the sampling device and the endoscope 100 and being beneficial to timely sampling in the optimal sampling time period; the mounting case 200 is provided with a suction inlet port 201 for communicating with the suction passage 11 of the endoscope 100 and a suction outlet port 202 for communicating with an external power source, the control member 300 is movably provided on the mounting case 200, and has a sampling path 34 for inputting a tissue sample to the sampling member 400, the control member 300 is switchable to a first state or a second state, in the first state, the sampling passage 34 communicates between the suction inlet 201 and the suction outlet 202, so that the sampling passage 34 can normally input the tissue sample into the sampling member 400, and when it is necessary to cut off the sampling, it is only necessary to switch the control member 300 to the second state, therefore, the communication between the sampling passage 34 and the suction inlet 201 and/or the suction outlet 202 can be cut off, in the sampling mode, an additional on-off structure is not required to be arranged between the mounting shell 200 and the control member 300, the whole structure of the sampling device is simple, and meanwhile, the sampling passage 34 can be effectively controlled.

Further, referring to fig. 4, 8 to 10, the sampling path 34 includes a first sampling branch 341 and a second sampling branch 342, and the first sampling branch 341 and the second sampling branch 342 are independent from each other. The first sampling branch 341 comprises a first connection port 3411 and a first sampling port 3412, and the second sampling branch 342 comprises a second connection port 3421 and a second sampling port 3422, wherein the first and

second sampling ports

3412 and 3422 are adapted to be placed in the sampling member 400, the first connection port 3411 is in communication with the suction inlet 201 and the second connection port 3421 is in communication with the suction outlet 202 when the control member 300 is in the first state, and the first connection port 3411 is not in communication with the suction inlet 201 and the second connection port 3421 is not in communication with the suction outlet 202 when the control member 300 is in the second state.

The control member 300 includes a body portion 31 and a stab portion 32 connected to the body portion 31. The main body 31 is movably connected to the mounting case 200, the first connection port 3411 and the second connection port 3421 are both located on the main body 31, and the main body 31 is movable to a first state or a second state relative to the mounting case 200. The insertion portion 32 extends from the end of the body portion 31 along the first axis 31a, and the end of the insertion portion 32 has a tapered configuration that gradually decreases in size in a direction from one end contacting the body portion 31 to the other end. The first and

second sampling ports

3412 and 3422 are located at the end of the bayonet portion 32. The sampling member 400 can be mounted on the mounting case 200 along the direction of the first axis 31a, and the bayonet portion 32 is inserted into the sampling member 400 to realize the abutment of the first and

second sampling ports

3412 and 3422 with the sampling member 400.

Preferably, in order to avoid the main body portion 31 from being separated from the sampling member 400 when moving, thereby causing leakage of the sampling member 400, in the present embodiment, the main body portion 31 is rotatably connected to the mounting case 200, and the rotation axis direction of the main body portion 31 coincides with the first axis 31a direction. The body portion 31 can be rotated to a preset angle to interface the sampling path 34 with the aspiration inlet 201, the aspiration outlet 202. In order to simplify the rotation structure between the body 31 and the mounting case 200 and facilitate the attachment and detachment of the body 31, in the present embodiment, the body 31 has a cylindrical shape, and the circumferential side of the body 31 is rotatably restrained in the mounting case 200. Indeed, in other embodiments, a rotation structure (not shown) may be disposed between the main body 31 and the mounting shell 200 to guide the main body 31 to rotate, and the description of the present invention is omitted here.

In addition, the control member 300 further includes a handle portion 33 connected to the main body portion 31, the handle portion 33 is located outside the mounting case 200, and a user can rotate the main body portion 31 by rotating the handle portion 33. The handle portion 33 may have a cylindrical structure, a rectangular parallelepiped structure, an irregular and irregular structure, etc., and may be further modified based on these structures to facilitate the user to hold the control member 300 with hands, so as to drive the control member 300 to move. In the present embodiment, the handle portion 33 includes at least one, preferably two, protruding portions 331 extending outward from the peripheral side of the main body portion 31 and disposed opposite to each other. The handle portion 33 is provided with a first indicator 332 for indicating the state of the control element 300, in this embodiment, the first indicator 332 is provided on the protrusion 331, and the first indicator 332 is a one-way arrow provided along the extending direction of the protrusion 331. The mounting shell 200 is provided with two second indication marks 203, the number of the second indication marks 203 is two, the second indication marks 203 can be one-way arrows, character marks or a combination of the two, when the control member 300 rotates to the first state, the first indication mark 332 corresponds to one of the second indication marks 203, and when the control member 300 rotates to the second state, the first indication mark 332 corresponds to the other one of the second indication marks 203, so that a user can accurately and quickly switch the state of the control member 300.

Further, since the suction channel 11 of the endoscope 100 is generally used to drain excess body fluid from the body during the actual operation. As shown in fig. 6 and 7, as a preferred embodiment, the control member 300 is further provided with a drainage passage 35, and the drainage passage 35 is independent from the sampling passage 34. When the control member 300 is in the second state, the drainage path 35 is abutted between the suction inlet 201 and the suction outlet 202 so that the body fluid is directly drained from the drainage path 35 into a designated position without the sampling member 400. The liquid discharge path 35 includes a third connection port 351 and a fourth connection port 352 in the main body 31, the third connection port 351 being adapted to be in contact with the suction inlet 201, and the fourth connection port 352 being adapted to be in contact with the suction outlet 202. Preferably, a buffering structure (not shown) is provided between the power source and the suction outlet 202, and the buffering structure is capable of buffering the human tissue sample discharged from the suction outlet 202.

In a preferred embodiment, the cross-sectional shapes of the sampling passage 34 and the drainage passage 35 are circular or quasi-circular so as not to generate dead flow space. The diameter of the drainage passage 35 is 1.5 to 3mm, and the diameter of the first sampling branch 341 is not smaller than the diameter of the second sampling branch 342.

Further, referring to fig. 2, 3 and 7, the mounting case 200 includes a first mounting part 21 and a second mounting part 22, wherein the first mounting part 21 is used for connecting the control member 300 and the sampling member 400, and the second mounting part 22 is used for connecting the endoscope 100.

The first mounting member 21 comprises a first mounting portion 211 and a second mounting portion 212 which are connected with each other, the control member 300 is connected with the first mounting portion 211, the sampling member 400 is connected with the second mounting portion 212, an avoiding space is arranged between the first mounting portion 211 and the second mounting portion 212, and the control member 300 can extend from the avoiding space to the sampling member 400 to be connected with the sampling member 400 in an abutting mode, so that the tissue sample flows into the sampling member 400.

The first mounting portion 211 is provided with a first mounting cavity 2111 for receiving the control member 300, and the second mounting portion 212 is provided with a second mounting cavity 2121 for receiving the sampling member 400. The first mounting cavity 2111 is formed by recessing from the first mounting portion 211 to the second mounting portion 212, the second mounting cavity 2121 is formed by recessing from the second mounting portion 212 to the first mounting portion 211, and an opening is formed between the first mounting cavity 2111 and the second mounting cavity 2121 to form the above-mentioned avoiding space. When mounted, the control member 300 is loaded into the first mounting portion 211 from the open side of the first mounting portion 211, the sampling member 400 is loaded into the second mounting portion 212 from the open side of the second mounting portion 212, and the control member 300 can be driven to be inserted into the sampling member 400 while the sampling member 400 is loaded into the second mounting portion 212.

Further, the inner wall of the first mounting cavity 2111 is a cambered surface structure adapted to the outer peripheral side of the body portion 31. The suction inlet 201 and the suction outlet 202 are both communicated with the first mounting chamber 2111 to connect the sampling passage 34 or the drainage passage 35 between the suction inlet 201 and the suction outlet 202 after the main body portion 31 is rotated by a preset angle. Preferably, the first mounting portion 211 is provided with two connecting heads 23, the two connecting heads 23 are respectively arranged at the suction inlet 201 and the suction outlet 202, and the two connecting heads 23 are respectively used for being butted with the endoscope 100 and an external power source. The connector 23 may be of a plug-in type, a screw connection type, etc., and the structure thereof is not described herein again.

In an embodiment, the inner wall of the first mounting cavity 2111 and the outer periphery of the main body 31 are closely attached to each other, so as to reduce the gap between the main body 31 and the mounting case 200, thereby improving the sealing performance of the connection between the sampling passage 34 and/or the drainage passage 35 and the aspiration inlet 201 and the aspiration outlet 202, and increasing the friction between the control member 300 and the first mounting cavity 2111, so that the control member 300 is not easy to rotate relative to the first mounting cavity 2111 when not subjected to a rotational force, and the reliability of the control member 300 is improved.

Preferably, a sealing member (not shown) may be further disposed between the first mounting cavity 2111 and the main body portion 31, and the sealing member is disposed around the main body portion 31 to improve the sealing performance at the communication position between the main body portion 31 and the first mounting cavity 2111. The number of the seal members is at least two, and is provided on both sides of the suction inlet 201 and the suction outlet 202 along the axial direction of the main body portion 31, i.e., the first axial line 31a direction. The sealing element can be an O-shaped sealing ring, a V-shaped sealing ring and the like, and can be made of rubber and other materials with certain elastic deformation capacity. In addition, the inner wall of the first mounting cavity 2111 and/or the outer wall of the main body 31 may be provided with a mounting groove (not shown) to mount the sealing member and restrict the sealing member from moving in the axial direction of the main body 31.

Further, the sampling device further includes a first limiting structure, which is adapted to limit the control member 300 from moving in the direction of the first axis 31a after the control member 300 is mounted to the preset position.

Specifically, as shown in fig. 4 and 5, the first limiting structure includes a first limiting portion 311, a first clamping portion 312, and a second limiting portion 2112. The first limiting portion 311 protrudes from the peripheral side of the main body portion 31, and is located at one end of the main body portion 31 away from the insertion portion 32, the first limiting portion 311 is continuously or intermittently distributed along the circumferential direction of the main body portion 31, and the control member 300 can gradually extend into the first mounting cavity 2111 along the first axis 31a, and is mounted when the first limiting portion 311 abuts against the opening side of the first mounting cavity 2111.

The first clamping portions 312 protrude from the peripheral side of the main body 31 and are located at one end of the main body 31 away from the first limiting portion 311, the first clamping portions 312 are continuously or intermittently distributed along the peripheral direction of the main body 31, and the first clamping portions 312 can move towards the direction away from the inner wall of the first mounting cavity 2111 when being subjected to an acting force perpendicular to the first axis 31a direction and reset when the acting force is removed. The second limiting portions 2112 are recessed in the inner wall of the first mounting cavity 2111 away from the opening side, and the second limiting portions 2112 are continuously or intermittently distributed along the circumferential direction of the first mounting cavity 2111. When the control member 300 is installed in the installation case 200 along the first axis 31a, the first engaging portion 312 is restricted by the inner wall of the first installation cavity 2111 and moves in a direction away from the inner wall to ensure that the main body portion 31 smoothly enters the first installation cavity 2111, and in this process, the first engaging portion 312 gradually moves toward the second limiting portion 2112 and is outwardly reset when reaching the second limiting portion 2112 to engage with the second limiting portion 2112, and at the same time, the first limiting portion 311 abuts against the opening side of the first installation cavity 2111. The first stopper portion 311 can restrict the movement of the control member 300 when the control member 300 is pushed in the direction of the first axis 31a, and the second stopper portion 2112 can restrict the movement of the control member 300 when the control member 300 is pulled in the direction of the first axis 31 a.

In order to facilitate the first catching portion 312 to smoothly enter the first mounting cavity 2111 during mounting, the first catching portion 312 includes a first guide surface 3121 facing the first mounting cavity 2111, and the first guide surface 3121 is inclined outward from a side away from the first stopper portion 311 to the other side with respect to the first axis 31 a. The maximum distance of the first guide surface 3121 to the first axis 31a is greater than the distance of the inner wall of the first mounting cavity 2111 to the first axis 31 a. When the first catching portion 312 is fitted into the first mounting cavity 2111, the first catching portion 312 will move away toward the first axis 31a under the guide of the first guide surface 3121.

In addition, the first catching portion 312 further includes a second guide surface 3122 connected to a side of the first guide surface 3121 adjacent to the inner wall of the first installation cavity 2111, the second guide surface 3122 facing the inner wall of the first installation cavity 2111 to abut against the inner wall of the first catching portion 312 after it enters the first installation cavity 2111 and guide the installation of the control member 300.

The second stopper portion 2112 includes a fourth guide surface 2113, and the distance from the fourth guide surface 2113 to the first axis 31a is longer than the distance from the first mounting cavity 2111 to the first axis 31a to form a stopper surface 2114 that restricts movement of the first click portion 312 between the fourth guide surface 2113 and the inner wall of the first mounting cavity 2111.

Preferably, in order to facilitate the removal of the control member 300 out of the first mounting cavity 2111, the first catching portion 312 further includes a third guide surface 3123, the third guide surface 3123 is connected to an opposite side of the second guide surface 3122 from the side contacting the second guide surface 3122 to the other side, and the third guide surface 3123 is inclined toward the first axis line 31 a. The stopper surface 2114 is inclined toward the first axis 31a to be slope-fitted with the third guide surface 3123. When the control member 300 needs to be removed from the first mounting cavity 2111, only the pulling force needs to be increased along the first axis 31a, and at this time, the first clamping portion 312 is guided by the limiting surface 2114 to move towards the first axis 31a, and the distance between the second guide surface 3122 and the first axis 31a is reduced, so that the second guide surface 3122 contacts with the inner wall of the first mounting cavity 2111.

Further, the first clamping portion 312 is made of a material with a certain elastic deformation capability, and/or the main body portion 31 is made of a material with a certain elastic deformation capability, so that when the first clamping portion 312 receives an acting force in a direction perpendicular to the first axis 31a, the first clamping portion can move towards the first axis 31a and avoid the first installation cavity 2111. The first limiting portion 311, the first engaging portion 312 and the main body 31 may be integrally formed or separately formed and then assembled together.

In one embodiment, referring to fig. 9 and 10, the main body 31 has a first arm portion 313 extending from one end of the main body 31 contacting the insertion portion 32 along the first axis 31a, and the first arm portion 313 is intermittently distributed along the circumferential direction of the main body 31. The diameter of the first arm portion 313 is preferably the same as the diameter of the main body portion 31 to closely fit the inner wall of the first mounting cavity 2111. The first clamping portion 312 is disposed on the first arm portion 313, an avoiding space is provided between the first arm portion 313 and the insertion portion 32, and the first arm portion 313 can be bent inward when receiving an acting force in a direction perpendicular to the first axis 31a, so as to drive the first clamping portion 312 to move toward the first axis 31 a. In the present embodiment, the first arm portions 313 are two in number and symmetrically disposed on both sides of the first axis 31 a.

Further, the sampling device includes a second limit structure adapted to rotate the control member 300 between the first limit position and the second limit position. When the control member 300 is moved to the first limit position, the sampling passage 34 is in the first state, and when the control member 300 is moved to the second limit position, the sampling passage 34 is in the second state.

Specifically, referring to fig. 8 and 10, the second limiting structure includes a holding block 36 disposed on the control member 300, and the holding block 36 may be disposed on the main body 31 and/or the handle portion 33. The mounting case 200 is provided with a limiting groove 24 for accommodating the abutting block 36, the limiting groove 24 extends along the moving direction of the abutting block 36, and the abutting block 36 can rotate to two end portions of the limiting groove 24 along with the control member 300 to reach a first limit position and a second limit position. In this embodiment, the limiting groove 24 is disposed at the opening side of the first mounting portion 211, and the limiting groove 24 may be formed by being inwardly recessed from the opening side of the first mounting portion 211; or at least two limiting blocks (not shown) are convexly arranged on the opening side of the first mounting part 211, and a limiting groove 24 is formed between every two adjacent limiting blocks; or the opening side of the first mounting part 211 is convexly provided with a limit ring 25 which is arranged around the periphery of the main body part 31, and part of the limit ring 25 is cut off to form a limit groove 24; the first stopper portion 311 may abut against a stopper or a stopper ring 25 on the opening side of the first mounting cavity 2111.

Further, referring to FIG. 11, the sampling member 400 includes a collector 41, a cover 42, and a cover 43. The collector 41 is of a bottle structure and is provided with a collection port 411. The cover 42 is connected to the collector 41, and the cover 42 and the collector 41 can be fixed by screw connection, snap connection, etc. An inner cavity 421 is opened inward from one side of the cover body 42 facing the collecting opening 411, and the inner cavity 421 is used for being matched and connected with the collector 41. The cover portion 43 is at least partially a flexible structure that can be pierced by the insertion portion 32, and the cover portion 43 is fixedly received in the inner cavity 421 and covers the collection opening 411. In order to ensure that the insertion part 32 can smoothly insert the sealing part 43 through the cover 42, the insertion opening 422 is provided on the side of the inner cavity 421 opposite to the opening side thereof, the sealing part 43 simultaneously seals the insertion opening 422, and the insertion part 32 can enter the collector 41 through the insertion opening 422, the sealing part 43 and the collecting opening 411 in sequence.

The capping portion 43 may be made of one of silicone rubber, fluoro-rubber, butyl rubber, PTFE material, or a composite material made of an arrangement of the above materials. The cap 43 has elasticity, so that the sealing performance between the insertion part 32 and the cap 43 can be maintained after the insertion part 32 is inserted, the sampling part 400 tends to recover to the original shape after being separated from the insertion part 32, and finally the sampling part is recovered to the shape before being punctured, namely, the sampling part is automatically closed, so that the tissue sample in the sampling part 400 is prevented from contacting with the external gas, and the sampling part 400 can be directly used for the examination and the test of other instruments without being turned over again.

In a preferred embodiment, the cover 43 is a composite gasket structure, the cover 43 includes a rubber layer 431 and a plastic layer 432, the rubber layer 431 has a first thickness, the plastic layer 432 has a second thickness, and the first thickness is greater than the second thickness. The rubber layer 431 faces the collecting opening 411, the plastic layer 432 faces the insertion opening 422 and the insertion portion 32, and the insertion portion 32 is inserted into the collector 41 through the plastic layer 432 and the rubber layer 431 in sequence. The plastic layer 432 may be PTFE or other plastic with good chemical stability as described above. By orienting the plastic layer 432 to the insertion opening 422, the plastic layer 432 can provide support when the insertion portion 32 is inserted, and before the insertion portion 32 reaches the rubber layer 431, partial insertion force of the insertion portion 32 is released through reverse resistance of the plastic layer 432, so that the problems that an avoidance space formed on the rubber layer 431 is too large due to too large insertion force when the insertion portion 32 is inserted, and further, cracking gaps are too large and/or too many are caused are reduced, the size of the avoidance space as small as possible and the cracking gaps accompanied therewith are ensured, and the sealing performance is improved. The second thickness of the plastic layer 432 is smaller, the first thickness of the rubber layer 431 is larger, the smaller thickness of the plastic layer 432 can ensure that the plastic layer can be easily inserted when the insertion force of the insertion part 32 is released, and the larger thickness of the rubber layer 431 can ensure the sealing effect. Moreover, after the plastic layer 432 is released, the state of the insertion portion 32 during and after insertion can be better maintained, the insertion portion 32 can be conveniently inserted into the collector 41 along the insertion direction, the regularity of the escape space formed after insertion of the insertion portion 32 is improved, and the escape space closed by the cap portion 43 rebounding when the insertion portion 32 is pulled out is better in sealing performance. In addition, with the above structure, the rubber layer 431 can be prevented from leaking, so that the self-resilience characteristic is prevented from being weakened due to the long-term contact of the rubber layer 431 with the outside, and the service life and the sealing performance of the sealing cover part 43 can be further prolonged.

In one embodiment, the rubber layer 431 and the plastic layer 432 preferably have a warped portion (not shown) protruding toward the cap 42, the warped portion makes the rubber layer 431 and the plastic layer 432 have a warped original shape, in this configuration, after the insertion portion 32 is inserted into the plastic layer 432 and the rubber layer 431, the plastic layer 432 and the rubber layer 431 have a tendency to return to the original warped shape due to self-resilience characteristics, and after the insertion portion 32 is finally stabilized, the deformation amount of the rubber layer 431 and the plastic layer 432 is smaller than that when the warped portion is not provided, so that an escape space and a crack gap formed on the rubber layer 431 after the insertion of the insertion portion 32 are smaller, and the sealing performance is better. In a more preferred embodiment, the outer diameters of the rubber layer 431 and the plastic layer 432 are slightly larger than the inner diameter of the inner cavity 421, and when the rubber layer 431 and the plastic layer 432 are disposed in the inner cavity 421 of the cap 42, the warping shape of the warping portion is enhanced, so that the plastic layer 432 and the rubber layer 431 have a stronger tendency to recover to the original warping shape, the escape space and the crack gap are smaller, and the sealing performance is better.

Further, referring to FIGS. 4, 6 and 7, the sampling member 400 is at least partially disposed in the second mounting cavity 2121. The sampling member 400 is detachably connected to the second mounting portion 212 of the mounting case 200 by one or more of clamping, screwing, magnetic attraction, and fastening. In the present embodiment, the cover 42 is received in the second mounting cavity 2121, and the cover 42 and the second mounting cavity 2121 are preferably fixed in a snap-fit manner.

The cover 42 and the second mounting cavity 2121 may be snapped together in a manner similar to the snapping structure of the control member 300 and the first mounting cavity 2111. The second mounting portion 212 is provided with a plurality of notches 2122 along the first axis 31a from the opening side, a second arm 2123 is formed on a side wall between two adjacent notches 2122 of the second mounting portion 212, a second locking portion 2124 is protruded from an inner wall of the second arm 2123, the second locking portion 2124 is located at a position of the second mounting portion 212 close to the opening side, a structure of the second locking portion 2124 is similar to that of the first locking portion 312, and the description of the present invention is omitted. When the cover 42 is installed, the cover 42 is inserted from the opening side of the second mounting cavity 2121 along the first axis 31a, and when the cover passes through the second blocking portion 2124, a force for driving the second arm portion 2123 outwards is provided, so that the second arm portion 2123 smoothly passes through the second blocking portion 2124, when the cover 42 abuts against the side of the second mounting cavity 2121 away from the opening side, the cover 42 is installed in place, and at this time, the second arm portion 2123 is reset and the cover 42 is limited to be detached from the second mounting cavity 2121.

Further, the second mount 22 can be removably coupled to the endoscope 100 by one or more of a snap fit, threaded connection, fasteners, and the like. In the present embodiment, the second attachment member 22 is fixed to the endoscope 100 by a sample clamp for easy attachment and detachment. Specifically, the second mounting member 22 is a ferrule having a certain elasticity, when the second mounting member 22 is sleeved on the endoscope 100, the second mounting member 22 is supported by the outer contour of the endoscope 100 to expand outward, so that the second mounting member is smoothly sleeved on the periphery of the endoscope 100, and meanwhile, the second mounting member 22 can be supported by the endoscope 100 under the action of the resilient force to be fastened on the endoscope 100.

In addition, the mounting housing 200 further includes a connecting member 26 received between the second mounting member 22 and the first mounting member 21, wherein the connecting member 26 enables an escape gap between the first mounting member 21 and the endoscope 100, thereby preventing the endoscope 100 from restricting the attachment and detachment of the control member 300 and the sampling member 400. Preferably, the first mounting element 21, the second mounting element 22 and the connecting element 26 are integrally formed for ease of mounting.

In addition, as shown in fig. 1, the present invention also provides an endoscope system including the aforementioned sampling device and an endoscope 100, wherein the sampling device is detachably attached to the endoscope 100 by a second attachment 22, the endoscope 100 is provided with a suction passage 11, the suction passage 11 communicates with a suction inlet 201, and a tissue sample in a human body can enter the suction inlet 201 along the suction passage 11.

It should be noted that the endoscope 100 in the endoscopic system of the present application refers to an endoscope that can be used for observation and/or treatment, and the endoscope 100 of the present application encompasses all endoscopes 100, such as bronchoscopes, nasoscopes, enteroscopes, duodenoscopes, laparoscopes, etc., and types including, but not limited to, optical endoscopes, electronic endoscopes, fiberscopes, etc., which are within the scope of the present application.

Preferably, the endoscope system further includes a tube member 500 and a suction valve 600. The duct member 500 is received between the suction passage 11 and the suction inlet 201, and the suction valve 600 controls opening and closing of the duct member 500. The suction valve 600 has an on state and an off state, and the suction valve 600 is switchable from the off state to the on state in response to a pressing operation. By adopting the pressing structure, the suction valve 600 can be operated when the user holds the endoscope 100, so that the start and stop of sampling can be controlled in time.

The tube member 500 and the suction valve 600 may be integrated with the endoscope 100 or the sampling device, and the tube member 500 may be integrally formed with the endoscope 100 or the sampling device, which is not limited herein. The suction valve 600 may be provided on the suction passage 11; alternatively, on the piping member 500; or at the junction of the suction passage 11 and the duct member 500.

In one embodiment, the tube member 500 is detachably connected between the suction passage 11 and the suction inlet 201 to facilitate replacement of subsequent parts of the endoscope system. The suction valve 600 is connected between the suction path 11 and the duct member 500, thereby avoiding the need to add an additional connecting structure to connect the suction path 11 and the duct member 500. Preferably, the suction valve 600 is fixedly provided to the endoscope 100, and the suction passage 11 and the tube member 500 are further fixed to the endoscope 100, so that the suction passage 11 and the tube member 500 are prevented from being connected and then shaken. Further, the duct member 500 is preferably a flexible tubular structure in order to facilitate the connection between the suction valve 600 and the suction inlet 201, and preferably, the duct member 500 may be provided between the suction passage 11 and the suction valve 600 so as to facilitate the connection between the suction valve 600 and the suction passage 11.

The installation process of the invention is as follows: the control member 300 is snapped into the first mounting portion 211 from the open side of the first mounting portion 211; the second mounting member 22 is snapped onto the endoscope 100 to enable connection of the sampling device to the endoscope 100; the sampling piece 400 is snapped into the second mounting part 212 from the opening side of the second mounting part 212, and in the process, the insertion part 32 of the control member 300 is inserted into the sampling piece 400; then, two ends of a pipeline piece 500 are respectively connected with the outlet of the suction valve 600 and the connecting head 23 at the suction inlet 201, so as to realize the pipeline communication between the sampling device and the endoscope 100; both ends of the other pipe member 500 are connected to the inlet of the suction valve 600 and the suction passage 11, respectively; the connection 23 at the suction outlet 202 is connected to an external power source to provide suction power.

The working principle of the invention is as follows: when the body tissue sample is not to be collected, the control member 300 is rotated to the second state in which the drainage passage 35 is received between the suction inlet 201 and the suction outlet 202; the power source is opened and the suction valve 600 is pressed, at this time, the power source sucks the drainage channel 35, so that the air pressure value in the drainage channel 35 is lower than the air pressure at the position of the tissue sample to be collected in the human body, and the tissue sample passes through the suction channel 11, the suction valve 600 and the drainage channel 35 in sequence under the action of the air pressure difference and is discharged from the suction outlet 202 for buffering.

When the user deems it necessary, if necessary, to take an appropriate amount of tissue sample, control member 300 is rotated to a first state, in which sampling passage 34 is received between suction inlet 201 and suction outlet 202; the power source is opened, and the suction valve 600 is pressed, at this time, the second sampling branch 342 connected with the suction outlet 202 sucks the internal space of the sampling member 400 from the second sampling port 3422, so that the air pressure value at the internal space of the sampling member 400 is lower than the air pressure outside the sampling member 400 and the air pressure at the position of the tissue sample to be collected in the human body, and the tissue sample passes through the suction passage 11, the suction valve 600 and the first sampling branch 341 in sequence under the action of the air pressure difference and enters the sampling member 400 from the first sampling port 3412 to form the tissue sample mixture 44.

When the user considers that the tissue sample amount is sufficiently collected or other necessary conditions, the control member 300 may be rotated to the second limit position, or the pressing state of the suction valve 600 may be released, or the power source may be turned off, etc., to prevent the tissue sample from continuously flowing into the sampling member 400. The control mode has the diversity, and the simple operation to deal with various emergency.

When the user does not stop the sampling operation in time, since the first sampling port 3412 and the second sampling port 3422 are both located in the sampling member 400, the tissue sample mixture 44 will gradually increase and fill the air portion 45 of the sampling member 400, and when the tissue sample mixture 44 completely covers the second sampling port 3422, the tissue sample mixture 44 will stop increasing and keep dynamic balance at the second sampling port 3422, thereby ensuring the safety of use.

In summary, the present invention has at least the following advantages:

1. the collecting device comprises the control part, the mounting shell and the sampling part, and the structure and the manufacturing process are simpler than those of the prior art on the premise of ensuring the sampling efficiency and effect, thereby being beneficial to improving the production efficiency, saving energy and lowering the cost.

2. The sampling device has good sealing performance, and the first connecting port, the second connecting port, the third connecting port and the fourth connecting port of the control part are tightly attached to the mounting shell, so that the first connecting port, the second connecting port, the third connecting port and the fourth connecting port can be tightly connected when being butted with the suction inlet and the suction outlet, and leakage is avoided; and a sealing element is arranged between the control element and the mounting shell, and the communication part of the control element and the mounting shell is positioned in a closed space formed by the sealing element, so that the leakage-proof effect can be further realized.

3. Adopt between sampling piece and the control to insert thorn mode and realize the butt joint, easy operation, and sampling piece when taking off from the installation shell after the sampling is accomplished, the closing cap portion on the sampling piece can automatic closure, has prevented the inside tissue sample of sampling piece and the contact of outside gas, and the sampling piece can directly be used for the inspection chemical examination of other instruments, need not to have enough to meet the need once more.

4. The sampling device is directly fixed on the endoscope to form an endoscope system, has strong linkage and is beneficial to timely and effectively sampling in the best sampling time period.

5. The control piece state switching reliability is good, the control piece is tightly attached to the mounting shell, the required rotating force of the control piece is large, the control piece is not prone to rotating in an unstressed state, the sampling device is provided with a second limiting structure, and the second limiting structure can guide a user to rotate the control piece to a first state or a second state.

The above description is only for the purpose of illustrating embodiments of the present invention and is not intended to limit the scope of the present invention, and all modifications, equivalents, and equivalent structures or equivalent processes that can be used directly or indirectly in other related fields of technology shall be encompassed by the present invention.

Claims

1. A tissue sample sampling device, comprising:

a mounting case (200) for being disposed on an endoscope (100), the mounting case (200) including a suction inlet (201) to be interfaced with the endoscope (100) and a suction outlet (202) to be interfaced with an external power source;

a sampling member (400) provided on the mounting case (200); and

the control piece (300) is movably arranged on the mounting shell (200), and a sampling passage (34) for inputting a tissue sample to the sampling piece (400) is arranged on the control piece (300);

wherein the control (300) has a first state and a second state, the sampling passage (34) interfacing between the aspiration inlet (201) and the aspiration outlet (202) when the control (300) is in the first state; when the control (300) is in the second state, the sampling passage (34) is not interfaced with the aspiration inlet (201) and/or the aspiration outlet (202).

2. The tissue sample sampling device according to claim 1, wherein the sampling path (34) comprises:

a first sampling branch (341) comprising a first connection port (3411) and a first sampling port (3412);

a second sampling branch (342) comprising a second connection port (3421) and a second sampling port (3422);

wherein the first sampling port (3412) and the second sampling port (3422) are disposed in the sampling member (400), the first connection port (3411) communicates with the suction inlet (201) and the second connection port (3421) communicates with the suction outlet (202) when the control member (300) is in the first state, the first connection port (3411) does not communicate with the suction inlet (201) and the second connection port (3421) does not communicate with the suction outlet (202) when the control member (300) is in the second state.

3. The tissue sample sampling device according to claim 1, wherein a drainage channel (35) is provided on the control member (300), the drainage channel (35) interfacing between the suction inlet (201) and the suction outlet (202) when the control member (300) is in the second state.

4. The tissue sample sampling device according to claim 2, wherein the control (300) comprises:

a main body part (31) movably connected with the mounting shell (200);

a piercing section (32) that is connected to the main body section (31) and can pierce into the sample piece (400) along the direction of attachment/detachment of the sample piece (400);

wherein the first sampling port (3412) and the second sampling port (3422) are both located on the bayonet portion (32), and the body portion (31) is movable to the first state or the second state with respect to the mounting case (200).

5. The tissue sample sampling device according to claim 4, wherein the mounting housing (200) comprises a first mounting (21), the first mounting (21) comprising:

a first mounting part (211) for connecting the main body part (31), wherein the main body part (31) can rotate relative to the first mounting part (211);

a second mounting portion (212) for connecting the sampling member (400);

the first installation part (211) and the second installation part (212) are provided with an avoidance space therebetween, and the insertion part (32) can extend to the sampling piece (400) from the avoidance space.

6. The tissue sample sampling device according to claim 5, wherein the first mounting portion (211) is provided with a first mounting cavity (2111), the suction inlet (201) and the suction outlet (202) are both communicated with the first mounting cavity (2111), and a peripheral side of the body portion (31) is in close contact with an inner wall of the first mounting cavity (2111).

7. The tissue sample sampling device according to claim 6, characterized in that it comprises a first stop structure adapted to limit the movement of said body portion (31) in the direction of its axis of rotation.

8. The tissue sample sampling device according to claim 6, wherein a sealing member is provided between the mounting housing (200) and the body portion (31), the sealing member sealing at a communication position of the control member (300) and the mounting housing (200).

9. The tissue sample sampling device according to claim 5, wherein the second mounting portion (212) defines a second mounting cavity (2121), and the sampling member (400) is at least partially removably and fixedly received in the second mounting cavity (2121).

10. The tissue sample sampling device according to claim 1, wherein said tissue sample sampling device comprises a second stop structure adapted to move said control member (300) between a first limit position, wherein said sampling passage (34) is in said first state, and a second limit position, wherein said sampling passage (34) is in said second state when said control member (300) is moved to said first limit position.

11. The tissue sample sampling device according to claim 4, wherein the control member (300) further comprises a grip portion (33) for moving the body portion (31), the grip portion (33) projecting relative to the body portion (31).

12. The tissue sample sampling device according to claim 4, wherein the sampling member (400) comprises:

a collector (41) having a collection port (411);

a cover (42) connected to the collector (41); and

a cover (43) provided on the lid (42) and covering the collection opening (411);

wherein the cover part (43) is at least partially of a flexible structure which can be punctured by the puncture part (32).

13. The tissue sample sampling device according to claim 12, wherein said flexible structure is made of one of silicone rubber, viton rubber, butyl rubber, PTFE material, or a composite material made from an array of the above materials.

14. The tissue sample sampling device according to claim 12, wherein said cover portion (43) comprises a rubber layer (431) and a plastic layer (432), said rubber layer (431) facing said collection port (411) and said plastic layer (432) facing said insertion portion (32).

15. The tissue sample sampling device of claim 1, wherein the sampling member (400) is removably coupled to the mounting housing (200) by one or more of a snap-fit, a threaded connection, a magnetic attraction, and a fastener.

16. The tissue sample sampling device according to claim 5, wherein the mounting housing (200) comprises:

a second mounting member (22) detachably connected to the endoscope (100);

a connector (26) which is received between the second mounting section (22) and the first mounting section (21) and which provides an escape gap between the first mounting section (21) and the endoscope (100).

17. An endoscopic system, comprising:

the tissue sample sampling device of any one of claims 1 to 16;

an endoscope (100), said tissue sample sampling device being provided on said endoscope (100); and

and a suction passage (11) provided in the endoscope (100) and communicating with the suction inlet (201).

18. The endoscopic system of claim 17, further comprising:

a duct member (500) connected between the suction passage (11) and the suction inlet (201);

a suction valve (600) connected to the suction passage (11) and/or the piping member (500);

wherein the suction valve (600) has an on state and an off state, the suction valve (600) being switched from the off state to the on state in response to a pressing operation.