TWI746073B - Continuous flow vial - Google Patents

Abstract

A continuous flow vail is provided, including an upper cover and a body. The upper cover has an upper portion, a lower portion, and an injection neck. The injection neck extends through the upper and lower portions and has a first open end and a second open end on the top and bottom surfaces of the upper cover, respectively. The body has a containing space, a main channel, a first flow channel and a second flow channel, and the containing space, the main channel, the first flow channel and a second flow channel communicate with each other, wherein a liquid passes through the first flow channel and the second flow channel respectively to flow into or out of the main channel. The upper cover is suitable for assembling to the body. When the upper cover is assembled to the body, the containing space of the body is used for accommodating the lower part of the upper cover.

Description

Continuous flow vials

The present invention relates to a continuous-flow type sample bottle, and particularly relates to a continuous-flow type sample bottle that can update samples in real time.

Generally speaking, when performing continuous monitoring and analysis, in addition to manually collecting samples according to time requirements, and putting them into the autosampler for analysis, you can also install an automatic switching valve as a sample injection device, which can be switched according to the collection time. Sample.

However, collecting samples manually will take a considerable amount of time. If more than several days of monitoring are required, manual collection is even more difficult, and the instrument must be taken for sample analysis at any time after the collection is completed. The advantage of the automatic switching valve of the device is that the collected samples can be injected in time, and there is no problem of manpower burden for a long time, especially in the use of continuous monitoring. However, the use of automatic switching valves for continuous monitoring usually means using a set of instruments to monitor one pipeline. If multiple pipelines are required for continuous monitoring, in addition to the high price of multiple sets of automatic switching valves, the triggering and control of analytical instruments Whether to provide multiple sets of control functions is also a problem that cannot be solved even with money.

Based on the above, in the continuous monitoring and analysis, how to improve the shortcomings of manual sample collection and time consumption, and solve the problems of high cost and control function of the automatic switching valve of the device are important directions for current research.

The invention provides a continuous flow sample bottle that can update samples in real time. It can not only be used for continuous monitoring and analysis, but also does not require additional control functions to be set by the instrument. The original automatic sampler can be used to complete continuous long-term sample injection. .

The continuous flow sample bottle of the present invention includes an upper cover and a body. The upper cover has an upper part, a lower part and an injection necking. The injection necking penetrates the upper part and the lower part and respectively has a first open end and a second open end on the top surface and the bottom surface of the upper cover. The width of the upper part is greater than the width of the lower part. The body has an accommodation space, a main channel, a first flow channel and a second flow channel, and the accommodation space, the main channel, the first flow channel and the second flow channel are in communication with each other, and the liquid passes through the first flow channel and the second flow channel respectively Into or out of the main channel. The upper cover is suitable for assembling to the main body. When the upper cover is assembled to the main body, the accommodating space of the main body is used to accommodate the lower part of the upper cover, and the syringe is inserted into the main channel of the main body from the injection neck.

In an embodiment of the present invention, the injection neck has an inclined side wall, and the inclined side wall connects the first open end and the second open end, and the width of the injection neck gradually increases from the first open end to the second open end along the inclined side wall. Shrink.

In an embodiment of the present invention, when the upper cover is assembled to the body, the accommodating space accommodates the lower part of the upper cover, and there is a gap between the bottom surface of the upper cover and the bottom surface of the accommodating space.

In an embodiment of the present invention, when the upper cover is assembled to the main body, the assembly method of the accommodating space of the main body and the lower part of the upper cover includes screw-type screw assembly.

In an embodiment of the present invention, the first flow channel and the second flow channel are respectively connected to the upper end and the lower end of the main channel.

In an embodiment of the present invention, the liquid flows into the main channel through the second flow channel, and flows out of the main channel through the first flow channel.

In an embodiment of the present invention, the lower end design of the main channel includes a tapered design.

In an embodiment of the present invention, the first flow channel and the second flow channel respectively include a first part and a second part. Compared with the second part, the first part is closer to the main channel, and the width of the first part is smaller than that of the second part. width.

In an embodiment of the present invention, the first flow channel and the second flow channel are respectively connected to liquid pipelines located outside the body, so that the liquid flows into or out of the main channel through the first flow channel and the second flow channel, respectively.

In an embodiment of the present invention, the liquid pipeline is inserted into the first flow channel and the second part of the second flow channel from the outside of the body.

Based on the above, the present invention provides a continuous flow sample bottle that can update samples in real time. It can not only be used for continuous monitoring and analysis, but also does not require additional control functions to be set by the instrument. The original automatic sampler can be used to complete the continuous length of the sample. Time injection. In this way, compared to manual sample collection, the continuous flow sample bottle of the present invention can not only perform long-term continuous monitoring and analysis, save a lot of manpower, but also can accurately control the monitoring time by the instrument, and quickly and instantly obtain monitoring results. In addition, compared to the automatic switching valve sampling device, the continuous flow sample bottle of the present invention does not require additional setting and control, and the function of the original automatic sampler can be used for sample injection.

The inventive concept can be embodied in many different forms and should not be regarded as limited to the exemplary embodiments presented herein. Rather, these exemplary embodiments are provided so that this disclosure will be complete and complete, and will fully express the concept of the present invention to those with ordinary knowledge in the technical field to which this case belongs. However, it should be understood that the inventive concept is not intended to be limited to the specific forms disclosed, on the contrary, the inventive concept will cover all modifications, equivalents and alternatives falling within the spirit and scope of the inventive concept. Throughout the specification and the drawings, the same reference numerals represent the same elements. In the drawings, in order to make the concept of the present invention clear, the size of the structure is enlarged.

It should be understood that although the terms "first" and "second" herein can be used to describe different elements, these elements should not be limited by these terms. These terms are only used to distinguish elements from each other. For example, the first element may be referred to as the second element, and, similarly, the second element may be referred to as the first element without departing from the protection scope of the inventive concept.

The term set used herein is only used for the purpose of describing particular embodiments and is not intended to limit the inventive concept. As used in the present invention, the singular form "one" will also include the plural form, unless explicitly specified otherwise herein. It will also be understood that the term "comprises", when used in this specification, specifies the presence of the described features, wholes, steps, operations, elements and/or elements, but does not exclude one or more features, wholes The existence or addition of, steps, operations, elements, elements, and/or groups thereof.

Unless otherwise defined, all terms (including technical terms and scientific terms) used herein have the same meanings commonly understood by those with ordinary knowledge in the technical field to which the present invention belongs. It will also be understood that terms (such as those defined in commonly used dictionaries) should be interpreted as having meaning consistent with the meaning in the relevant technical context, and should not be interpreted in an idealized or overly formal sense, unless in This is clearly defined as such.

In the drawings, the shape shown can be modified as desired according to manufacturing technology and/or tolerances. Therefore, the exemplary embodiments should not be viewed as being limited to the specific shape of the illustrated area. During the manufacturing process, these shapes can be changed.

The terms "and/or" or "and/or" as used in the present invention include any and all combinations of one or more related listed items.

In the drawings, the same or similar reference numerals may indicate the same or similar components, so for the explained components, reference may be made to the corresponding drawings or description content, and redundant descriptions may be omitted.

FIG. 1 is a three-dimensional schematic diagram of a continuous flow sample bottle according to an embodiment of the present invention. 2 is a schematic cross-sectional view of a continuous flow sample bottle according to an embodiment of the present invention. Fig. 3 is a schematic cross-sectional view of an assembly of a continuous flow sample bottle according to an embodiment of the present invention.

1 and 2, the continuous flow sample bottle 10 includes an upper cover 20 and a body 30. Although the continuous flow sample bottle 10 including the upper cover 20 and the body 30 is shown in FIG. 1 as a cylindrical shape, the present invention is not limited to this. The upper cover 20 and the body 30 can also be square or rectangular to allow continuous flow. The sample bottle 10 exhibits a square or rectangular configuration. In this embodiment, the material of the upper cover 20 may include various plastics and engineering plastics, such as PP, PE, PEEK, Teflon, Bakelite, Vespel, and various metals, such as stainless steel, iron, and aluminum alloy. The material of the body 30 can include various plastics and engineering plastics, such as PP, PE, PEEK, Teflon, Bakelite, Vespel, and various metals, such as stainless steel, iron, and aluminum alloys, but the present invention does not take this as limit. The continuous flow sample bottle 10 of the present invention can be directly placed in a general autosampler (autosampler) for use, or a special sample tray can be used.

1 and 2, the upper cover 20 has an upper portion 22, a lower portion 24, and an injection neck 26. The injection neck 26 penetrates the upper portion 22 and the lower portion 24 and has first open ends P1 and P1 on the top and bottom surfaces of the upper cover 20, respectively. For the second open end P2, the width of the upper part 22 is greater than the width of the lower part 24. The injection neck 26 has an inclined side wall, which connects the first open end P1 and the second open end P2, and the width (diameter) of the injection neck 26 in the first direction D1 is along the inclined side wall from the first open end P1 toward The second open end P2 is tapered.

1 and 2, the width (diameter) of the upper part 22 in the first direction D1 is, for example, 10 mm to 13 mm, and the height in the second direction D2 is, for example, 2 mm to 8 mm. The width (diameter) of the lower part 24 in the first direction D1 is, for example, 4 mm to 9 mm, and the height in the second direction D2 is, for example, 4 mm to 8 mm. In this way, the total height of the upper cover 20 in the second direction D2 is, for example, 6 mm to 16 mm. The width of the injection neck 26 in the first direction D1 at the first open end P1 is, for example, 4 mm to 8 mm, and the width at the second open end P2 is, for example, 1 mm to 4 mm. However, the present invention is not limited to this, and the dimensions of the aforementioned components can also be adjusted according to actual operation requirements.

1 and 2, the main body 30 has an accommodation space 32, a main channel 34, a first channel 36 and a second channel 38, and the accommodation space 32, the main channel 34, the first channel 36 and the second channel 38 They communicate with each other, and the liquid flows into or out of the main channel 34 through the first channel 36 and the second channel 38 respectively. The first channel 36 and the second channel 38 are respectively connected to the upper end and the lower end of the main channel 34. In more detail, the liquid preferably flows into the main channel 34 through the second channel 38 connected to the lower end, and flows out of the main channel 34 through the first channel 36 connected to the lower end. The actual operating conditions adjust the inflow or outflow of the liquid in the first channel 36 and the second channel 38. Although the lower end design of the main channel 34 is shown in FIG. 2 as a right-angle design, the present invention is not limited to this. The lower end design of the main channel 34 can also be a rounded corner or a tapered design (please refer to Another embodiment and the description of Figure 4 below).

1 and 2, the first channel 36 and the second channel 38 respectively include a first part A1 and a second part A2. Compared with the second part A2, the first part A1 is closer to the main channel 34, and the first part A1 is in The width in the second direction D2 is smaller than the width of the second portion A2 in the second direction D2. In this embodiment, the first channel 36 and the second channel 38 are respectively connected to the liquid pipes 40 and 50 located outside the body 30 so that the liquid flows into or out of the main channel 34 through the first channel 36 and the second channel 38 respectively. The liquid pipelines 40, 50 are inserted into the second part A2 of the first channel 36 and the second channel 38 from the outside of the body 30, that is, the second part A2 is mainly used as a fixing place of the liquid pipelines 40, 50, and the first part A1 is mainly used as a fluid channel. In more detail, the way in which the liquid pipes 40 and 50 are inserted into the first channel 36 and the second channel 38 can be simply inserted and fixed, or can be fixed by adhesive, or can be fixed by a general pipeline joining tool, such as Nut , Necking collar, etc., or other fixing methods. According to an embodiment of the present invention, the liquid pipelines 40 and 50 can be fitted with a rubber collar, and then fixed to the first channel 36 or the second channel 38 of the main body 30 with a flat-head non-protruding screw joint. When the flat-head non-protruding screw joint is fixed, the rubber collar will be squeezed to fix the liquid pipelines 40, 50 and tightly fit the inner wall of the first channel 36 or the second channel 38 to achieve The function of preventing liquid leakage in the liquid pipelines 40 and 50. In addition, the flat-head non-protruding screw joint is used for fixing, because there is no fixing object protruding out of the main body 30, which facilitates installation in an autosampler for use.

1 and 2, the width (diameter) of the body 30 in the first direction D1 is, for example, 10 mm to 13 mm, and the height in the second direction D2 is, for example, 20 mm to 30 mm. The width (diameter) of the accommodating space 32 in the first direction D1 is, for example, 4 mm to 9 mm, and the height in the second direction D2 is, for example, 3 mm to 9 mm. The width (diameter) of the main channel 34 in the first direction D1 is, for example, 1 mm to 4 mm, and the height in the second direction D2 is, for example, 10 mm to 25 mm. The gap between the main channel 34 and the bottom of the main body 30 in the second direction D2 is, for example, 0.1 mm to 5 mm, and this gap can be designed to be adjusted in accordance with the base. For the first channel 36 and the second channel 38, the length of the first part A1 in the first direction D1 is, for example, 0 mm to 2 mm, and the width in the second direction D2 is, for example, 0.05 mm to 1 mm; the second part A2 The length in the first direction D1 is, for example, 2 mm to 4 mm, and the width in the second direction D2 is, for example, 1 mm to 5 mm. However, the present invention is not limited to this, and the dimensions of the aforementioned components can also be adjusted according to actual operation requirements. Although the first channel 36 and the second channel 38 are shown in FIG. 2 as having the same size, the present invention is not limited to this. The first channel 36 and the second channel 38 may also have different sizes.

Please refer to FIG. 1, FIG. 2 and FIG. 3, the upper cover 20 is suitable for assembling to the main body 30. When the upper cover 20 is assembled to the body 30, the accommodating space 32 of the body 30 is used for accommodating the lower part 24 of the upper cover 20, and there is a gap G between the bottom surface of the upper cover 20 and the bottom surface of the accommodating space 32. The gap G is configured with a gasket. The height of the gap G in the second direction D2 is, for example, 0 mm to 3 mm. A syringe (not shown) is inserted into the main channel 34 of the body 30 from the injection neck 26. In this embodiment, the syringe is, for example, an injection needle, but the invention is not limited to this. As shown in FIGS. 1, 2 and 3, when the upper cover 20 is assembled to the main body 30, the accommodating space 32 of the main body 30 and the lower portion 24 of the upper cover 20 are assembled by screwing, for example, but the present invention does not Not limited to this.

4 is a schematic cross-sectional view of a continuous flow sample bottle according to another embodiment of the present invention. The embodiment shown in FIG. 4 is similar to the embodiment shown in FIG. 1, FIG. 2 and FIG. Referring to FIG. 4, the difference between this embodiment and the above-mentioned embodiment is that in the body 30 of the continuous flow sample bottle 10A, the lower end of the main channel 34A may be a tapered design, so that the necking design adjusts sampling.

In summary, the present invention provides a continuous flow sample bottle that can update samples in real time. It can not only perform continuous monitoring and analysis, but also does not require additional control functions of the instrument. That is, the original automatic sampler can be used to complete Continuous long-term injection of samples. Compared with manual collection, the continuous flow sample bottle of the present invention can be monitored for a long time and save a lot of manpower, and the monitoring time can also be accurately controlled by the instrument, and the monitoring result can be obtained in the fastest and instantaneous manner. Compared with the automatic switching valve sampling device, the continuous flow sample bottle of the present invention does not require additional setting and control, and the function of the original automatic sampler can be used for sample injection. In addition, the general automatic switching valve sampling device usually can only target one monitoring flow path at a time. If multiple monitoring flow paths are required, even if the control can be set, the cost of the automatic switching valve is quite high. In contrast, because the continuous flow sample bottle of the present invention is placed in the general sample bottle position of the autosampler, more than one sample bottle can be placed. If multiple continuous flow sample bottles of the present invention are placed, The instrument can monitor multiple flow paths in sequence. In addition, the continuous flow sample bottle of the present invention is sampled and analyzed by an autosampler. All functions of the autosampler in the original instrument and equipment can continue to be used, such as control of sample sampling volume, automatic sample derivation, and automatic Analysis and other functions such as dilution.

10.10A: Continuous flow vials 20: Upper cover 22: upper part 24: lower part 26: Injection necking 30: body 32: accommodating space 34, 34A: main channel 36: First channel 38: Second channel 40, 50: Liquid pipeline A1: The first part A2: Part Two D1: First direction D2: second direction G: gap P1: The first open end P2: second open end

FIG. 1 is a three-dimensional schematic diagram of a continuous flow sample bottle according to an embodiment of the present invention. 2 is a schematic cross-sectional view of a continuous flow sample bottle according to an embodiment of the present invention. Fig. 3 is a schematic cross-sectional view of an assembly of a continuous flow sample bottle according to an embodiment of the present invention. 4 is a schematic cross-sectional view of a continuous flow sample bottle according to another embodiment of the present invention.

10: Continuous flow vials

20: Upper cover

22: upper part

24: lower part

26: Injection necking

30: body

40, 50: Liquid pipeline

D1: First direction

D2: second direction

Claims (8)

A continuous flow type sample bottle, comprising: an upper cover with an upper part, a lower part and an injection necking, the injection necking penetrates the upper part and the lower part and has first open ends on the top surface and the bottom surface of the upper cover, respectively And a second open end, the width of the upper part is greater than the width of the lower part; and the body has an accommodating space, a main channel, a first flow channel, and a second flow channel, and the accommodating space, the main channel, The first flow channel and the second flow channel are in communication with each other, and liquid flows into or out of the main channel through the first flow channel and the second flow channel respectively, wherein the upper cover is suitable for assembling to the The body, when the upper cover is assembled to the body, the accommodating space of the body is used to accommodate the lower portion of the upper cover, and the syringe is inserted into the main channel of the body from the injection neck Wherein the injection neck has an inclined side wall, the inclined side wall connects the first open end and the second open end, and the width of the injection neck extends from the first open end along the inclined side wall. The open end is tapered toward the second open end, wherein the first flow channel and the second flow channel respectively include a first part and a second part. Compared with the second part, the first part is closer to the The main channel, and the width of the first part is smaller than the width of the second part. The continuous flow sample bottle according to claim 1, wherein when the upper cover is assembled to the body, the accommodating space accommodates the lower part of the upper cover, and the bottom surface of the upper cover and the accommodating space There are gaps between the bottom surfaces of the space. The continuous flow sample bottle according to claim 1, wherein when the upper cover is assembled to the body, the assembly method of the accommodation space of the body and the lower part of the upper cover includes screw-type screw connection Assembly. The continuous flow sample bottle according to claim 1, wherein the first flow channel and the second flow channel are respectively connected to the upper end and the lower end of the main channel. The continuous flow sample bottle according to claim 4, wherein the liquid flows into the main channel through the second flow channel, and flows out of the main channel through the first flow channel. The continuous flow sample bottle according to claim 1, wherein the lower end design of the main channel includes a tapered design. The continuous flow sample bottle according to claim 1, wherein the first flow channel and the second flow channel are respectively connected to liquid pipes located outside the body, so that the liquid passes through the first flow channel respectively And the second flow channel flows into or out of the main channel. The continuous flow sample bottle according to claim 7, wherein the liquid pipeline is inserted into the second part of the first flow channel and the second flow channel from outside the body.

Images