TWI724629B - 緩瀉用錠劑 - Google Patents

緩瀉用錠劑 Download PDF

Info

Publication number
TWI724629B
TWI724629B TW108141442A TW108141442A TWI724629B TW I724629 B TWI724629 B TW I724629B TW 108141442 A TW108141442 A TW 108141442A TW 108141442 A TW108141442 A TW 108141442A TW I724629 B TWI724629 B TW I724629B
Authority
TW
Taiwan
Prior art keywords
tablet
magnesium oxide
particle size
volume
disintegrant
Prior art date
Application number
TW108141442A
Other languages
English (en)
Chinese (zh)
Other versions
TW202031249A (zh
Inventor
服部篤之
Original Assignee
日商協和化學工業股份有限公司
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 日商協和化學工業股份有限公司 filed Critical 日商協和化學工業股份有限公司
Publication of TW202031249A publication Critical patent/TW202031249A/zh
Application granted granted Critical
Publication of TWI724629B publication Critical patent/TWI724629B/zh

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
    • A61K33/08—Oxides; Hydroxides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38—Cellulose; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2095—Tabletting processes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/10—Laxatives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Inorganic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
TW108141442A 2018-11-16 2019-11-14 緩瀉用錠劑 TWI724629B (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2018215180 2018-11-16
JP2018-215180 2018-11-16

Publications (2)

Publication Number Publication Date
TW202031249A TW202031249A (zh) 2020-09-01
TWI724629B true TWI724629B (zh) 2021-04-11

Family

ID=70731929

Family Applications (1)

Application Number Title Priority Date Filing Date
TW108141442A TWI724629B (zh) 2018-11-16 2019-11-14 緩瀉用錠劑

Country Status (7)

Country Link
US (1) US12053549B2 (https=)
EP (1) EP3881897B1 (https=)
JP (3) JP7111389B2 (https=)
KR (1) KR102682646B1 (https=)
CN (1) CN113015555B (https=)
TW (1) TWI724629B (https=)
WO (1) WO2020101016A1 (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20250127725A1 (en) * 2021-08-20 2025-04-24 Setolas Holdings, Inc. Magnesium oxide tablets

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP7233516B2 (ja) * 2021-07-30 2023-03-06 セトラスホールディングス株式会社 酸化マグネシウムを含有する小児慢性機能性便秘症治療用医薬組成物
CN115487160A (zh) * 2022-09-27 2022-12-20 威海百合生物技术股份有限公司 一种氧化镁片及其制备方法
CN120036483B (zh) * 2025-01-06 2026-03-27 仙乐健康科技股份有限公司 一种微胶囊、片剂及其制备方法和应用

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102481315A (zh) * 2009-09-08 2012-05-30 协和化学工业株式会社 抗酸缓泻用片剂

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8710965D0 (en) * 1987-05-08 1987-06-10 Smith Kline French Lab Pharmaceutical compositions
JP4015485B2 (ja) 2001-08-27 2007-11-28 協和化学工業株式会社 制酸・緩下用錠剤
KR20080099353A (ko) * 2001-08-27 2008-11-12 교와 가가꾸고교 가부시키가이샤 제산 ·완하용 정제
JP2006022060A (ja) 2004-07-09 2006-01-26 Kyowa Chem Ind Co Ltd 制酸・緩下用水分散液およびそのための錠剤
AU2007203715B2 (en) * 2006-01-05 2012-08-02 Veloxis Pharmaceuticals A/S Disintegrating loadable tablets
BRPI0811303A2 (pt) * 2007-05-08 2015-01-27 Hercules Inc Formulação de comprimido de desintegranção rápida robusta
CA2687063C (en) 2007-05-11 2017-04-04 Aloebiotics Research Labs, Inc. Aloe preparation for skin enhancement
JP2010265208A (ja) 2009-05-14 2010-11-25 Kyowa Chem Ind Co Ltd 膵臓機能強化乃至活性化用複合酸化マグネシウム粒子
JP2014224080A (ja) * 2013-05-17 2014-12-04 協和化学工業株式会社 大腸の検査または手術のための処置剤

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102481315A (zh) * 2009-09-08 2012-05-30 协和化学工业株式会社 抗酸缓泻用片剂

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20250127725A1 (en) * 2021-08-20 2025-04-24 Setolas Holdings, Inc. Magnesium oxide tablets

Also Published As

Publication number Publication date
US12053549B2 (en) 2024-08-06
CN113015555A (zh) 2021-06-22
EP3881897B1 (en) 2026-02-18
CN113015555B (zh) 2023-05-30
US20210401754A1 (en) 2021-12-30
JPWO2020101016A1 (ja) 2021-09-02
WO2020101016A1 (ja) 2020-05-22
EP3881897A4 (en) 2022-08-10
JP7360503B2 (ja) 2023-10-12
EP3881897A1 (en) 2021-09-22
KR102682646B1 (ko) 2024-07-09
TW202031249A (zh) 2020-09-01
KR20210076066A (ko) 2021-06-23
JP2023165999A (ja) 2023-11-17
JP2022105754A (ja) 2022-07-14
JP7657275B2 (ja) 2025-04-04
JP7111389B2 (ja) 2022-08-02

Similar Documents

Publication Publication Date Title
TWI724629B (zh) 緩瀉用錠劑
JP6545839B2 (ja) 口腔内崩壊錠及びその製造方法
CA2755274C (en) Tablet and granulated powder containing 6-fluoro-3-hydroxy-2-pyrazinecarboxamide
KR20130030306A (ko) 약학 조성물
CN115803020A (zh) 含有苯磺酸米洛巴林的口腔崩解片剂
CN106714782A (zh) 具有滥用遏制性质的药物组合物
EP2262487A2 (en) An orally disintegrating tablet of cilostazol
JP2010001242A (ja) レバミピド固形製剤及びその製造方法
KR20140076998A (ko) 에스오메프라졸 유리염기 또는 그의 알칼리염을 포함하는 고미가 차폐된 약학 제제 및 이의 제조방법
CN103282051A (zh) 口腔内崩解片剂
AU2013347264B2 (en) Dispersible tablet
CN104159949A (zh) 持续释放型经口固体制剂
JP2006022060A (ja) 制酸・緩下用水分散液およびそのための錠剤
JPH05310570A (ja) 粒状製剤
US20150283083A1 (en) Dispersible Tablet
JP2006104194A (ja) 用時調製型レバミピド注腸製剤
HK40082826A (en) Orally disintegrating tablet containing mirogabalin besilate
JP6051059B2 (ja) エトドラク含有粒子及びエトドラク含有固形製剤
JP2005320267A (ja) 小型のクラリスロマイシン高含有錠剤及びその製造方法
Chandrakant Formulation and Evaluation of Oral Fast Disintegrating Tablets of Etoricoxib