TWI720075B - 使用微核醣核酸前驅物作爲誘導cd34陽性成體幹細胞增殖之藥物 - Google Patents

使用微核醣核酸前驅物作爲誘導cd34陽性成體幹細胞增殖之藥物 Download PDF

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TWI720075B
TWI720075B TW105139971A TW105139971A TWI720075B TW I720075 B TWI720075 B TW I720075B TW 105139971 A TW105139971 A TW 105139971A TW 105139971 A TW105139971 A TW 105139971A TW I720075 B TWI720075 B TW I720075B
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mir
rna
cells
cell
seq
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TW105139971A
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TW201735932A (zh
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希龍 林
欽次 張
堂熙 吳
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希龍 林
堂熙 吳
Wjwu & Lynn幹細胞硏究所
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Priority claimed from US15/048,964 external-priority patent/US10519440B2/en
Priority claimed from US15/167,226 external-priority patent/US9879263B2/en
Application filed by 希龍 林, 堂熙 吳, Wjwu & Lynn幹細胞硏究所 filed Critical 希龍 林
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TW105139971A 2015-12-02 2016-12-02 使用微核醣核酸前驅物作爲誘導cd34陽性成體幹細胞增殖之藥物 TWI720075B (zh)

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
US201562262280P 2015-12-02 2015-12-02
US62/262,280 2015-12-02
US15/048,964 2016-02-19
US15/048,964 US10519440B2 (en) 2012-08-10 2016-02-19 Composition and method of using miR-302 precursors as drugs for treating Alzheimer's diseases
US15/167,226 US9879263B2 (en) 2011-08-12 2016-05-27 Use of microRNA precursors as drugs for inducing CD34-positive adult stem cell expansion
US15/167,226 2016-05-27
WOPCT/US16/49583 2016-08-31
PCT/US2016/049583 WO2017095489A1 (en) 2015-12-02 2016-08-31 Use of microrna precursors as drugs for inducing cd34-positive adult stem cell expansion

Publications (2)

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TW201735932A TW201735932A (zh) 2017-10-16
TWI720075B true TWI720075B (zh) 2021-03-01

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TW105139971A TWI720075B (zh) 2015-12-02 2016-12-02 使用微核醣核酸前驅物作爲誘導cd34陽性成體幹細胞增殖之藥物

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EP (1) EP3384026A1 (enExample)
JP (1) JP2018535684A (enExample)
CN (1) CN108431227A (enExample)
TW (1) TWI720075B (enExample)
WO (1) WO2017095489A1 (enExample)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11624067B2 (en) 2008-05-07 2023-04-11 Shi-Lung Lin In-vitro induction of adult stem cell expansion and derivation
JP7718819B2 (ja) * 2018-07-02 2025-08-05 リン、シー-ラン 成体幹細胞の拡大と誘導のインビトロでの誘発
CN112430596B (zh) * 2019-08-26 2025-10-28 中国科学院上海营养与健康研究所 一类小rna分子及其类似物在抗衰老中的应用
US20220396778A1 (en) * 2021-06-12 2022-12-15 Shi-Lung Lin Novel RNA Composition and Production Method for Use in iPS Cell Generation

Citations (1)

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Publication number Priority date Publication date Assignee Title
TW201321507A (zh) * 2011-08-12 2013-06-01 Mello Biotechnology Inc 用於在原核細胞內使用真核第二型聚合酶啟動子驅動之轉錄作用的可誘導之基因表現組成物及其應用

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ATE484572T1 (de) 1997-04-16 2010-10-15 Unigene Lab Inc Direkte expression von peptiden ins kulturmedium
US9453219B2 (en) 2003-05-15 2016-09-27 Mello Biotech Taiwan Co., Ltd. Cosmetic designs and products using intronic RNA
US8080391B2 (en) 2004-12-22 2011-12-20 Ambrx, Inc. Process of producing non-naturally encoded amino acid containing high conjugated to a water soluble polymer
CN101970664B (zh) * 2008-01-16 2013-08-21 林希龙 使用可诱导的重组核糖核酸因子生成不含肿瘤的类胚胎干细胞的多能性细胞
US9879263B2 (en) * 2011-08-12 2018-01-30 Mello Biotechnology, Inc. Use of microRNA precursors as drugs for inducing CD34-positive adult stem cell expansion
US9422559B2 (en) * 2010-06-02 2016-08-23 Shi-Lung Lin Production and utilization of a novel anti-cancer drug in therapy
WO2014026189A2 (en) * 2012-08-10 2014-02-13 Shi-Lung Lin Production and utilization of a novel anti-cancer drug in therapy
US10196662B2 (en) * 2012-08-10 2019-02-05 Mello Biotechnology, Inc. Composition for producing microRNA precursors as drugs for enhancing wound healing and production method of the microRNA precursors

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW201321507A (zh) * 2011-08-12 2013-06-01 Mello Biotechnology Inc 用於在原核細胞內使用真核第二型聚合酶啟動子驅動之轉錄作用的可誘導之基因表現組成物及其應用

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Ming Yan.et al. Modulation of Gene Expression by Polymer Nanocapsule Delivery of DNA Cassettes Encoding Small RNAs. PLOS ONE | DOI:10.1371/journal.pone.0127986 June 2, 2015. *

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CN108431227A (zh) 2018-08-21
JP2018535684A (ja) 2018-12-06
TW201735932A (zh) 2017-10-16
WO2017095489A1 (en) 2017-06-08
EP3384026A1 (en) 2018-10-10

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