TWI667994B - Imaging device and displaying method by using indocyanine green - Google Patents

Abstract

A blood-green-based imaging device and a blood-green-green imaging display method, comprising: an excitation light source, comprising a mercury lamp, wherein a first filter is disposed thereon to stimulate the blood circulation green among the emitted light The excitation light passes through and is irradiated to the blood or lymph containing the blood-sucking green, so that it is excited to emit the emitted light; a camera module includes a gray-scale image capturing unit, and a second filter is disposed thereon So that the emitted light passes through the second filter and is injected into the grayscale image capturing unit to capture a blood vessel or a lymphatic image; a display module electrically connected to the grayscale image capturing unit . In this way, the low-cost mercury lamp is combined with an appropriate first filter to obtain the desired excitation light, and it is not necessary to be expensive and to find a specific laser diode as a light source, which is greatly cost-effective and makes it easy to start. For the patient. The blood vessel or lymphatic vessel image can be combined with the real human body image to form an augmented reality image.

Description

Video device for blood circulation green and image display method for blood green

A blood-green-based imaging device and a blood-green-green imaging display method, in particular, an imaging device using a mercury lamp as a blood-green-green excitation light source and an image of a blood vessel or a lymphatic vessel after angiography to amplify a real-life image. And camera method.

Lymphatic edema, difficulty in walking, skin swelling into chrysanthemum tissue or even skin due to lymphatic edema or obstruction due to lymphatic fibrosis or obstruction caused by surgery or other unknown causes. There are problems such as cellulitis. At present, there is surgery to connect the lymphatic vessels directly into the vein to return the lymph fluid, which can quickly improve this problem.

For example, there are cancer patients whose doctors often take a test of the surrounding lymph nodes at the affected area to determine whether there are problems such as the presence or metastasis of cancer cells.

However, because the width of the lymphatic vessels is not easy to find, the doctor often determines the position before the operation to perform the operation. However, if the lymphatic angiography is used frequently by using the blood circulation green, the blood is first applied and the blood is green. When circulating in the affected area, after emitting the excitation light and receiving the emitted light of the stimulated radiation, the image is presented, allowing the physician to quickly find and mark the location of the lymphatics (junction) to begin surgery.

At present, there is a hand-held blood-green fluorescent image recognition device on the market, which is combined with a light source module that emits excitation light and a camera module that receives radiation, and is connected to the display on a handheld device. Device, however, the handheld blood-green fluorescent image recognition device When using it, it needs to be handled by a person, and the image stability is poor. Moreover, the light source module of the hand-held blood-green fluorescent image recognition device needs to be small in size, and can simultaneously emit excitation light of a desired power and a wavelength range, and a specific laser diode is often required. As a result, the cost is very high, and it is difficult to get started, which makes the current popularization difficult.

Therefore, in order to improve the above-mentioned deficiencies, the present invention provides a blood-green-based imaging device, comprising: an excitation light source, comprising a mercury lamp and a first filter, the first filter being disposed on the mercury lamp The light emitted by the mercury lamp is used to excite light that circulates blood green as a excitation light, and the first filter is a band pass filter having a filter wavelength of 760 nm to 790 nm; the excitation Light is used to illuminate blood or lymph containing blood green, so that blood or lymph containing blood circulation green is stimulated to emit light; a camera module comprising a grayscale image capturing unit and a second filter The second filter is disposed in the grayscale image capturing unit, and the second filter is a band pass filter having a filtering wavelength of 830 nm to 870 nm; the camera module is configured to pass the emitted light The second filter is then injected into the grayscale image capturing unit to capture a blood vessel or lymphatic image according to the position of the emitted light; and a display module electrically connected to the grayscale image capturing unit for This blood vessel or lymphatic vessel image is displayed.

Further, the display module includes an image processing unit and a display unit, and the image processing unit is electrically connected to the grayscale image capturing unit and the display unit to present the blood vessel or lymphatic tube image to the display unit.

Further, the image processing unit is an AR image processing unit for superimposing the blood vessel or lymphatic vessel image on a real human body image to form an augmented reality image, and the augmented reality is displayed by the display unit. image.

Further, further comprising a moving stage, the moving stage is configured to set the excitation light source, the camera module and the display module, the moving stage is provided with a setting frame, the excitation light source and the imaging The modules are disposed in the setting bracket with one of the universal joints.

Further, the power of the mercury lamp is in the range of 75 W to 125 W.

The invention further provides a method for displaying a blood green color, comprising: an excitation light source emitting a light wave having a wavelength between 760 nm and 790 nm and exciting the blood green, as an excitation light; the excitation light is used for illuminating the blood containing green blood. The blood or lymph fluid, such that the blood or lymph containing blood circulation green stimulates a radiation having a wavelength between 830 nm and 870 nm; a gray scale image capturing unit draws a blood vessel or lymph according to the position of the emitted light Tube image; the blood vessel or lymphatic vessel image is displayed by a display module.

Further, the image of the blood vessel or the lymphatic vessel is superimposed on a real human body image by an AR image processing unit to form an augmented reality image.

According to the above technical features, the following effects can be achieved:

1. Using a mercury lamp in combination with a suitable first filter, the excitation light of a desired specific power and wavelength can be obtained, and a specific laser diode that is not expensive and difficult to find can be used as a light source, which is greatly cost-effective.

2. The excitation light source and the camera module are separately arranged on the moving stage, and the use is relatively stable without image shaking problem. Moreover, the angle adjustment of the universal joint and the movement of the moving stage can be applied to the blood-green green imaging of each part, and the use is convenient.

3. The camera module cooperates with the grayscale image capturing unit of the "grayscale" to capture the image of the emitted light, so that the image presented on the display unit has a higher sharpness and improves the accuracy of the physician's diagnosis.

4. The overall use of relatively low-cost related equipment, you can achieve the demand for blood-based green angiography, making it easy to start, more accessible and beneficial to patients.

5. In order to avoid the light wave of other wavelengths affecting the interpretation of the blood vessel or lymphatic vessel image, we will filter the emitted light before performing the contrast. Therefore, we use AR technology to superimpose the blood vessel or lymphatic vessel image on the real human body to form an augmented reality image, which can be judged intuitively by the physician. The location of the blood vessel or lymphatic vessel is in the human body, and it is easier to accurately locate the lesion.

(1)‧‧‧Excitation source

(11) ‧‧‧ Mercury lamp

(12)‧‧‧First filter

(2) ‧‧‧ camera module

(21)‧‧‧ Grayscale image capture unit

(22)‧‧‧Second filter

(3)‧‧‧ display module

(31)‧‧‧Image Processing Unit

(32)‧‧‧Display unit

(4) ‧‧‧Mobile stage

(41)‧‧‧Setting rack

(411), (412) ‧ ‧ universal joint

(a) ‧ ‧ excitation light

(b) ‧‧‧radiation

[First figure] is a schematic perspective view of the apparatus for illuminating the green blood of the present embodiment.

[Second image] is a functional block diagram of the blood-staining green camera of the present embodiment.

In summary of the above technical features, the main effects of the blood-green-green imaging device and the blood-green imaging method of the present invention will be clearly shown in the following embodiments.

Referring to the first figure, the blood-green imaging device of the embodiment includes an excitation light source (1) including a mercury lamp (11) and a first filter (12). Wherein, the light emitted by the mercury lamp (11) contains light that can stimulate the blood green, and the power of the mercury lamp (11) is 100W in this embodiment. The first filter (12) is disposed on the mercury lamp (11), and the first filter (12) is a band pass filter having a filter wavelength of 760 nm to 790 nm.

A camera module (2) includes a grayscale image capturing unit (21) and a second filter (22). The grayscale image capturing unit (21) adopts a CCD (Charge-coupled Device) that captures grayscale images. The second filter (22) is disposed on the grayscale image capturing unit (21), and the second filter (22) is a band pass filter that filters a wavelength of 830 nm to 870 nm.

A display module (3) includes an image processing unit (31) and a display unit (32). The image processing unit (31) is electrically connected to the grayscale image capturing unit (21) and the display unit (32). The image processing unit (31) is, for example, a software package included in a computer host.

a moving stage (4) for providing the excitation light source (1), the camera module (2) and the display module (3), the mobile stage (4) is provided with a setting a frame (41), the excitation light source (1) and the camera module (2) are disposed on the setting frame (41) with one of the universal joints (411) (412), so that the excitation light source (1) and the The camera module (2) is traversed on the setting frame (41) and rotated at different angles.

Referring to the first figure and the second figure, the above device is used to perform the method of blood-green angiography, and when a blood-green image is injected for a person who has a blood-green test, the universal joint is adjusted and fixed ( 411), the light emitted by the mercury lamp is passed through the first filter (12), and is irradiated to a side of the side of the test subject with blood green, and remains fixed, and the first filter (12) Only light having a wavelength between 760 nm and 790 nm among the light emitted by the mercury lamp (11) is passed, and the light in the wavelength range can excite the blood green as an excitation light (a). When the excitation light is irradiated to the blood or lymph fluid containing the blood-sucking green in the to-be-side portion, the blood or lymph containing the blood-sucking green is stimulated to emit a light (b).

Adjusting and fixing the universal joint (412) so that the camera module (2) can be fixed toward the to-be-side portion, so that the emitted light can be incident on the gray-scale image through the second filter (22). The unit (21) is taken, and the grayscale image capturing unit (21) captures a blood vessel or lymphatic vessel image according to the position of the emitted light. The second filter (22) having a filter wavelength of 830 nm to 870 nm passes the main wavelength component of the emitted light (b), and filters out other wavelengths of light to remove noise.

The image processing unit (31) is preferably an AR image processing unit for superimposing the blood vessel or lymphatic vessel image on a real human body image to form an augmented reality image and present on the display unit ( 32).

Alternatively, if the doctor can see the position of the blood vessel or lymphatic vessel or the flow of blood or lymph, such as the blood or lymph fluid, of the test subject in the display unit (32), it is required for diagnosis or knife positioning.

One of the features and functions of this embodiment is:

1. The above-mentioned universal joint (411) (412) facilitates adjustment of the mercury lamp (11) correctly toward the side to be side and fixed, and facilitates adjustment of the camera module (2) correctly toward the to-be-side portion and fixing In order to capture the gray scale image, the shelf (41) maintains the stability of the mercury lamp (11) and the camera unit (2), thereby maintaining the stability of the illumination position and the stability of capturing the image. The grayscale image displayed on the display unit (32) has no problem of sloshing.

2. By using a low-cost mercury lamp (11) with a bandpass filter with a filter range of 760 nm to 790 nm at an appropriate power, an excitation light that excites the green blood can be generated, as compared to specific The way in which the laser diode produces the desired excitation light is greatly reduced in cost, and the low price also makes it easier to use.

3. Since the wavelength of the emitted light (b) incident on the gray scale image capturing unit (21) is between 830 nm and 870 nm, the gray scale image is captured by using a gray scale method. Taking the unit (21) to capture the blood vessel or lymphatic vessel image, the image processing unit (31) can have a higher image sharpness when the blood vessel or lymphatic vessel image is presented on the display unit (32). To improve the accuracy of the diagnosis. At the same time, the augmented reality image output of the blood vessel or lymphatic vessel image superimposed on the real human body image can be accurately positioned by the physician for diagnosis or surgery.

4. In addition, when the moving stage (4) is traversed, the part to be tested in the larger (long) range of the subject to be tested, such as the leg of the subject to be tested, can be photographed, and the use is also convenient. .

In view of the foregoing description of the embodiments, the operation and the use of the present invention and the effects of the present invention are fully understood, but the above described embodiments are merely preferred embodiments of the present invention, and the invention may not be limited thereto. Included within the scope of the present invention are the scope of the present invention.

Claims (6)

A blood-green-based imaging device includes: an excitation light source, comprising a mercury lamp and a first filter, wherein the first filter is disposed on the mercury lamp to make the light emitted by the mercury lamp The light that can stimulate the blood green is passed as an excitation light, and the first filter is a band pass filter having a filter wavelength between 760 nm and 790 nm; the excitation light is used for irradiating blood containing blood green Or lymph fluid, such that the blood or lymph containing blood circulation green is stimulated to emit a light; a camera module comprising a grayscale image capturing unit and a second filter, the second filter being disposed on a gray-scale image capturing unit, wherein the second filter is a band pass filter having a filtering wavelength between 830 nm and 870 nm; the camera module is configured to pass the emitted light through the second filter Injecting the grayscale image capturing unit to capture a blood vessel or a lymphatic vessel image according to the position of the emitted light; and a display module electrically connected to the grayscale image capturing unit for displaying the blood vessel or lymphatic vessel image a moving stage for setting the excitation light source, the camera And the display module, the mobile stage is provided with a setting frame, and the excitation light source and the camera module are disposed on the setting frame by one of the universal joints, so that the excitation light source and the camera module are disposed in the setting frame Move up and rotate at different angles. The image processing unit includes an image processing unit and a display unit, and the image processing unit is electrically connected to the grayscale image capturing unit and the display. a unit to present the blood vessel or lymphatic vessel image to the display unit. The image processing unit is an AR image processing unit for superimposing the blood vessel or lymphatic vessel image on a real human body image to form a camera body as claimed in claim 2, wherein the image processing unit is an AR image processing unit. The augmented reality image is augmented and the augmented reality image is displayed by the display unit. The apparatus for illuminating blood green as described in claim 1, wherein the power of the mercury lamp is in the range of 75 W to 125 W. A method for displaying blood through green blood, comprising: Using a mercury lamp as an excitation source to emit a light wave having a wavelength between 760 nm and 790 nm, which can stimulate blood green, as an excitation light; the excitation light is used to irradiate blood or lymph containing blood circulation green, so as to contain blood circulation The green blood or lymph fluid stimulates a radiation having a wavelength between 830 nm and 870 nm; a grayscale image capturing unit extracts a blood vessel or a lymphatic image according to the position of the emitted light; a blood vessel or a lymphatic vessel image; the display module is disposed on a moving stage, and a universal joint of the mercury lamp and the grayscale image capturing unit is disposed on one of the moving stages, so that the The mercury lamp and the grayscale image capturing unit are traversed on the setting frame and each rotates at different angles. For example, in the image display method of the blood green as described in claim 5, the image of the blood vessel or the lymphatic vessel is superimposed on a real human body image by an AR image processing unit to form an augmented reality image.