TWI659758B - Pharmaceutical infusion system - Google Patents

Abstract

A medicine infusion system includes a body, a pressure relief device, and a needle-free connector. Therefore, the present invention can be universally used for syringes or closed joints complying with ISO regulations and movable closed joints of different brands. Furthermore, the present invention can adjust the atmospheric pressure of the sealed bottle or bag, so that the toxic medicine can be easily extracted from the bottle or bag, and the toxic medicine can be prevented from remaining on the outer surface of the needle-free connector, and the toxic gas will not pass through the needle-free. The connector floats in the outer space. In addition, the present invention can prevent toxic drugs from entering the balloon by blocking the toxic drugs. In addition, the elastomer of the needle-free connector can completely scrape off the toxic drugs on the outer surface of the cylinder of the upper connector. In addition, the user can remove the balloon or the entire set of pressure relief devices to access or formulate non-toxic drugs.

Description

Pharmaceutical infusion system

The invention relates to a pharmaceutical infusion system, in particular to a pharmaceutical infusion system for preparing or taking toxic drugs and toxic gases contained in sealed bottles or sealed bags.

Some drugs are toxic, such as chemotherapy drugs to treat cancer. In order to reduce the risk of medical personnel from exposure to toxic drugs, the closed transfer of these toxic drugs has become very important. The outer surface of the needle-free connector used must not have a small amount of toxic drug residues. Toxic gases are scattered in the outer space, otherwise medical personnel accidentally contact toxic drugs, which will affect the nervous system, damage the reproductive system, and increase the risk of blood cancer.

The conventional medicine infusion system includes a body and a needle-free connector, which can be used for two purposes such as medicine taking and medicine adding.

When a user wants to remove a toxic drug from a sealed bottle or a sealed bag, first of all, connect the needle-free connector to a syringe or to a closed connector connected to the syringe or to a special connector connected to the syringe. The designed movable type closes the joint, and then pushes a piston to the innermost side of the syringe to evacuate the air in the syringe. Next, based on the principle that the dispensing infusion system is down and the sealed bottle or sealed bag is up, the puncture part of the body punctures the seal of the sealed bottle or sealed bag. Then, the piston is pulled from the inside of the syringe to the outside, so that the toxic drugs in the sealed bottle or the sealed bag pass through the dispensing infusion system from top to bottom, and then injected into the syringe to complete the correct medicine taking action.

However, in the process of taking medicine, because no clean gas is replenished into the sealed bottle or sealed bag, it is difficult to extract the toxic drug from the sealed bottle or sealed bag.

When adding drugs, some toxic drugs must be dissolved or diluted before use, so the toxic drugs must be withdrawn from a container by a syringe. Next, the needle-free connector of the conventional pharmaceutical infusion system is connected to the syringe or to a closed joint connected to the syringe or to a specially designed movable closed joint connected to the syringe. Then, based on the principle that the dispensing infusion system is up and the sealed bottle or bag is down, a puncture portion of the body punctures the seal of the sealed bottle or bag. Finally, the piston is used to push the toxic drug in the syringe from top to bottom through the catheter or closed joint or movable closed joint of the connection end of the syringe, so that the toxic drug passes through the dispensing infusion system from top to bottom, and then is injected into a sealed bottle or seal Inside the bag to complete the correct dosing action.

However, because the material of the sealed bottle is usually a hard and non-deformable material such as glass, when the toxic drug is injected into the sealed bottle, the atmospheric pressure in the sealed bottle will be greater than the external atmospheric pressure. , The gas in the sealed bottle will be depressurized through the needle-free connector, so that some of the toxic drugs in the sealed bottle will pass through the needle-free connector in the form of gas or by atomization, causing the toxic drugs to easily remain in the needle-free connection The outer surface of the device, toxic gases containing toxic drugs will also escape through the needle-free connector to the external space. At this time, the skin of medical staff may be exposed to toxic drugs, or they may inhale toxic gases into the lungs, affect the nervous system, damage the reproductive system, and increase the risk of blood cancer.

To this end, a drug infusion system includes a balloon, and the balloon is disposed on one side of the body.

In the process of taking medicine, first, the piston is moved to the innermost side of the syringe to push the clean air in the syringe through the body into the balloon, so that the balloon contains clean air and the clean air in the syringe is evacuated. While the toxic drug is injected into the syringe, The atmospheric pressure in the sealed bag is less than the external atmospheric pressure, so let the clean air in the balloon pass through the dispensing infusion system and then enter the sealed bottle or sealed bag to maintain the atmospheric pressure in the sealed bottle or sealed bag and the outside atmospheric pressure The same effect, while toxic drugs are easily extracted from sealed bottles or sealed bags.

During the dosing process, the toxic gas in the sealed bottle will enter the balloon to achieve the effect of pressure relief, so that the atmospheric pressure in the sealed bottle or sealed bag is maintained the same as the outside world, and some of the toxicity in the sealed bottle or sealed bag is avoided. The drug will pass through the needle-free connector in the form of gas or by atomization, so no toxic drug will remain on the outer surface of the needle-free connector, and the toxic gas will not be scattered in the external space through the needle-free connector. As a result, the skin of medical staff does not come into contact with toxic drugs and does not inhale toxic gases into the lungs.

Through the above-mentioned correct method of adding and taking medicine, toxic drugs will not enter the balloon through the body.

However, some medical personnel who lack ideas will set the dispensing infusion system underneath and the sealed bottle or sealed bag on the top, which will cause the toxic drugs injected into the sealed bottle or sealed bag to pass through the body from top to bottom. Into a balloon.

Another drug infusion system further includes a check valve, and the check valve is arranged on the body.

In the process of taking medicine, first, the piston is moved to the innermost side of the syringe to evacuate the clean air in the syringe. When the toxic drug is injected into the syringe, because the atmospheric pressure in the sealed bottle or sealed bag is less than the external atmospheric pressure, clean air is directly passed from the external space through the dispensing infusion system and then into the sealed bottle or sealed bag to achieve maintenance. The atmospheric pressure in the sealed bottle or sealed bag has the same effect as the external atmospheric pressure, and at the same time, the toxic drug is easily extracted from the sealed bottle or sealed bag.

During the dosing process, the toxic gas in the sealed bottle will pass through the check valve and enter the balloon to achieve the effect of pressure relief, so that the atmospheric pressure in the sealed bottle or sealed bag remains the same as the outside world, avoiding sealed bottles or seals Some of the toxic drugs in the bag will pass through the needle-free connector in the form of gas or by atomization, so no toxic drugs will remain on the outer surface of the needle-free connector, and the toxic gas will not drift through the needle-free connector. In the outer space. As a result, the skin of medical staff does not come into contact with toxic drugs and does not inhale toxic gases into the lungs.

However, this kind of dispensing infusion system still cannot prevent the problem of toxic drugs flowing into the balloon when the wrong way of adding medicine is added. Furthermore, the check valve has many problems such as complicated structure, large volume, high cost, and easy damage.

Furthermore, sometimes non-toxic drugs are taken or formulated, and the presence or absence of balloons does not affect the operation. However, the balloons of the above two conventional pharmaceutical infusion systems are fixed on the body and cannot be disassembled. Therefore, the user cannot remove the balloons according to his will to take or formulate non-toxic drugs, which is very inconvenient.

Also, there are two types of conventional needle-free connectors for pharmaceutical infusion systems. One type of needle-free connector can only be used with syringes that generally have connection ends (Luer fittings) in accordance with ISO 594-1 and 594-2 or with connection ends (Luer fittings) that comply with ISO 594-1 and 594-2 ) The combination of closed joints cannot be combined with specially designed movable closed joints. Another type of needle-free connector can be combined with a specially designed movable closed joint, but the structure is more complicated and the cost is higher, and because the structure of the movable closed joint designed by different brands is different, this type of needle-free connection The device can only be used for specific mobile closed joints.

The main object of the present invention is to provide a pharmaceutical infusion system, which can be universally used for syringes with connection ends (luer joints) according to ISO 594-1 and 594-2, and has connections according to ISO 594-1 and 594-2. End (Luer joint) closed joint and movable closed joint designed by different brands.

Another object of the present invention is to provide a pharmaceutical infusion system, which can adjust the atmospheric pressure of a sealed bottle or a sealed bag, so that the toxic medicine can be easily extracted from the sealed bottle or the sealed bag, and can avoid the toxic medicine remaining on the outside of the needle-free connector On the surface, noxious gas will not be scattered in the external space through the pin-free connector.

Yet another object of the present invention is to provide a dispensing and infusion system that can block toxic drugs through a barrier to prevent toxic drugs from entering the balloon. The barrier has a simple structure, a small volume, low cost, and is not easily damaged. Observe the wrong way of taking the medicine, and quickly fix it.

Yet another object of the present invention is to provide a pharmaceutical infusion system, in which the elastomer of the needle-free connector can completely scrape off the toxic drugs on the outer surface of the cylinder of the upper connector.

Another object of the present invention is to provide a medicine infusion system, in which a user can remove a balloon or a whole set of pressure relief devices to take or formulate a non-toxic medicine.

Another object of the present invention is to provide a pharmaceutical infusion system, which can prevent the cylinder from being exposed through the sheath, and achieve the effect of protecting the cylinder.

Yet another object of the present invention is to provide a dispensing and infusion system, which can increase the force of clamping the middle joint by the sleeve, so that the clamping block is not easy to detach from the top of the middle joint.

Yet another object of the present invention is to provide a drug infusion system. The small-diameter portion of the needle-free connector can be connected to the infusion tube in the form of a Y-shape or a T-shape. It can be connected with an infusion tube, and the medicine is introduced into the human body through the infusion tube and the intravenous injection system connected thereto.

In order to achieve the foregoing object, the present invention provides a medicine infusion system including a body, a pressure relief device, and a needle-free connector.

The body includes a screw connection portion and a puncture portion, and a first channel and a second channel are opened. The screw connection portion of the body is provided with an axial hole. The bottom end of the puncture portion has a tip, and the first channel axially extends at The puncture part penetrates the bottom end of the puncture part, the second channel extends axially from the puncture part and communicates with the shaft hole of the screw connection part of the body and penetrates the bottom end of the puncture part.

The pressure relief device includes a connection structure, a balloon, and a compartment. The connection structure is detachably provided on the body and a first-grade channel is opened. The flow channel communicates with the first channel of the body. The balloon is detachably provided on the body. In the connection structure, the partition layer is a filter paper or a filter film, is arranged on the flow channel, and is composed of a waterproof and breathable material, and has the ability to prevent the passage of liquid and the passage of gas.

The needle-free connector includes a screw connection portion, a large diameter portion, a small diameter portion, an upper tube, a lower tube, and an elastomer. The screw connection portion of the needle-free connector is provided on the large diameter of the needle-free connector. A shaft hole is provided on the top of the part, and the large-diameter part of the needle-free connector is provided between the screw-connected part of the needle-free connector and the small-diameter part of the needle-free connector and forms a container with a partition. The receiving space of the large-diameter portion of the needle-free connector communicates with the shaft hole of the screw-connecting portion of the needle-free connector, and the elastic body is disposed in the receiving space and extends to the needle-free connector. A shaft hole of the screw connection part, and a slit is opened on the top thereof, the upper pipe is provided inside the elastic body and an upper passage is opened, and the small diameter part of the needle-free connector and the partition plate together form a screw hole, The downcomer integrally extends from the partition to the screw hole of the small diameter portion of the needle-free connector and opens a lower channel, the lower channel further extends through the partition, and the outer side of the large diameter portion of the needle-free connector and The contact portion of the outer side of the small-diameter portion of the needle-free connector forms a first-level portion. The screw holes of the needle-free connector are screwed into the screw holes of the small-diameter part of the needle-free connector, so that the lower tube of the needle-free connector is inserted into the shaft hole of the screw connection part of the body.

Wherein, the needle-free connector group is provided on a movable closed joint; or, the needle-free connector is screwed on a connection end of a syringe or a connection end of a closed joint through a screw connection portion thereof.

Wherein, the movable closed joint includes a middle joint and an upper joint. The middle joint encloses a receiving slot and includes two clips. The upper joint includes a screw joint, a cylinder, and two clamp arms. The upper joint A shaft hole is provided in the screwed portion of the cylinder, and a shaft hole and one side opening are provided in the cylinder. The shaft hole of the cylinder communicates with the shaft hole of the screwed portion of the upper joint, and the side opening of the cylinder is connected to the shaft of the cylinder The holes are in communication, and the two clamping arms surround the cylinder.

Wherein, when the pin-free connector has not been combined with the movable closed joint, the pin-free connector is far from the middle joint.

Wherein, when the needle-free connector and the middle connector start to be combined, the needle-free connector is moved to the inside of the receptacle of the middle connector until the two clips of the middle connector clamp the step portion of the needle-free connector. until.

Wherein, when the middle joint and the upper joint start to be combined, the upper joint moves in the direction of the middle joint, and the cylinder of the upper joint is stretched out and passes through the slit of the elastomer of the needle-free connector to enter the The elastic body is pushed inside and pushes the upper tube downward until the two clamping arms of the upper joint clamp the screwed portion of the needle-free connector.

Preferably, the body is provided with a large-diameter hole extending radially and a small-diameter hole extending radially, and the small-diameter hole communicates between the first channel and the large-diameter hole.

Wherein, the connection structure of the pressure relief device includes a connecting member, the connecting member includes a plug-in portion, a ring body and a screw connection portion, the plug-in portion is inserted in the large-diameter hole and an axial hole is opened, and the ring body An axial hole and an insert groove are provided between the plug-in part and the screw joint part of the connecting member. The axial hole of the ring body communicates with the insert groove. The partition is provided in the insert groove and a part is located there. In the shaft hole of the ring body, a screw hole of the connecting member is provided with a shaft hole.

The connection structure of the pressure relief device includes a balloon assembly including a small diameter portion, a large diameter portion, a funnel portion, a front duct, and a rear duct. The small diameter portion of the balloon assembly A screw hole is formed together with a baffle, and the screwing part of the connecting member is screwed to the screw hole of the small diameter part of the balloon assembly, and the large diameter part of the balloon assembly is set to the small diameter of the balloon assembly. The funnel part is located at an end of the large-diameter part of the balloon assembly far from the small-diameter part of the balloon assembly and has a funnel-shaped opening. The front duct integrally extends from the baffle to the screw hole of the small diameter portion of the balloon assembly, is inserted into the shaft hole of the screw joint portion of the connecting member, and a front passage is opened, and the rear duct integrally extends from the baffle. A rear passage is opened in the shaft hole of the large diameter part of the balloon assembly and the funnel-shaped opening of the funnel part, and an open end of the balloon is sleeved on the outer side of the rear duct.

Among them, the axial hole of the insertion part of the connector, the axial hole of the ring body of the connector, the front channel of the front tube of the balloon assembly, and the rear channel of the rear tube of the balloon assembly are collectively defined as the flow. Road.

Wherein, the connection structure of the pressure relief device includes a set of rings, which are sleeved on the outer peripheral edge of the open end of the balloon, and the open end of the balloon is fixed on the outer side of the rear duct and the large part of the balloon assembly. Between the inner walls of the diameter section.

Preferably, at least a part of the insertion groove penetrates the outer peripheral surface of the ring body to form an arc-shaped slit, and the partition layer can enter and exit the insertion groove through the arc-shaped slit.

Preferably, the two clips are respectively disposed on two opposite sides of the outer peripheral surface of the middle joint, and the middle joint includes two convex portions respectively disposed on the other two sides opposite to the outer peripheral surface of the middle joint. Extending longitudinally, each convex portion is provided with a longitudinally extending long groove. The tops of the two long grooves are open and the bottom is closed. The inner side communicates with the receiving groove. When the middle joint and the upper joint begin to combine, the upper joint The joint moves in the direction of the middle joint, and the two clamping arms are slidably disposed in the two long grooves.

Preferably, the upper joint has a top wall and a ring wall, and the top wall and the ring wall together form a containing chamber. The screw joint of the upper joint is provided on the upper surface of the top wall, and the cylinder is provided on The lower surface of the top wall is located in the receiving chamber. Two opposite sides of the ring wall are respectively provided with two longitudinal grooves passing through the bottom thereof. The width of the two longitudinal grooves is greater than the width of the two convex portions. The lower surfaces of the top wall are respectively located in the two longitudinal grooves, and two clip blocks protrude from the inner sides thereof; when the pin-free connector has not been combined with the movable closed joint, the bottom of the clip blocks of the two clip arms abuts. Lean against the top of the middle joint, while the two clamp arms are located below the clamping block to clamp the middle joint; when the middle joint and the upper joint begin to combine, the two convex portions are slid in the two longitudinal grooves respectively In this way, until the clamping block of the two clamping arms abuts against the screw connection part of the needle-free connector, at this time, the part of the two clamping arms located below the clamping block clamps the screw connection part of the needle-free connector.

Preferably, the middle joint includes two limiting blocks, the two limiting blocks are respectively disposed on two opposite sides of the outer peripheral surface of the middle joint and are located above the two clamps, and the other two sides of the ring wall are respectively opened. Two sliding grooves, which do not penetrate the bottom of the ring wall, and the two limiting blocks are slid in the two sliding grooves respectively; when the needle-free connector has not been combined with the movable closed joint, the two The limiting blocks abut against the bottom ends of the two chute grooves; when the two clamping arms clamp the screw connection portion of the needle-free connector, the two limiting blocks abut against the lower surface of the top wall of the upper joint.

Preferably, the two opposite sides of the outer peripheral surface of the middle joint are respectively provided with two cut grooves penetrating through the bottom thereof, the two clip bodies respectively extend axially from the two cut grooves and the inner sides thereof respectively protrude from two clip blocks; When the pin connector starts to be combined with the middle connector, the pin-free connector moves to the inside of the receptacle of the middle connector until the clamping block of the two clip bodies clamps the step portion of the pin-free connector.

Preferably, the movable closed joint includes a plug body, which is provided in the receiving groove of the middle joint and has a shaft hole and a slit; when the needle-free connector has not been combined with the movable closed joint, The post of the upper joint is located in the shaft hole of the plug; when the two clips of the middle joint clamp the step portion of the pin-free connector, the bottom of the plug body abuts the elasticity of the pin-free connector Top of the body; when the middle joint of the movable closed joint and the upper joint begin to combine, the upper joint moves in the direction of the middle joint, and the pillars of the upper joint sequentially open and pass through the slits of the plug. And the slit of the elastomer of the needle-free connector to enter the interior of the elastomer.

Preferably, the upper joint has a top wall and a ring wall, and the top wall and the ring wall together form a containing chamber. The screw joint of the upper joint is provided on the upper surface of the top wall, and the cylinder is provided on The lower surface of the top wall is located in the receiving chamber; the drug infusion system further includes a sheath provided in the receiving chamber, with the top end abutting on the lower surface of the top wall of the upper joint and the bottom end abutting on the plug. Body, and the pillar is wrapped inside.

Preferably, the two clips are respectively disposed on two opposite sides of the outer peripheral surface of the middle joint, and two longitudinally extending long grooves are opened on the other two sides of the outer peripheral surface of the middle joint, and the tops of the two long grooves are open. , The bottom is closed, and the inner side communicates with the receiving groove; the middle joint includes two bosses, which respectively extend laterally from the outer side of the middle joint near the bottom wall of the two long grooves. Wherein, the upper joint has a top wall and a ring wall, the top wall and the ring wall together constitute a container, the screw joint of the upper joint is provided on the upper surface of the top wall, and the cylinder is provided on the top. The lower surface of the wall is located in the chamber. Two opposite sides of the annular wall are respectively provided with two longitudinal grooves penetrating through the bottom thereof. The width of the two longitudinal grooves is equal to the width of the two bosses, and the two clamping arms are provided on the top. The lower surfaces of the walls are respectively located in the two longitudinal grooves, and the inner sides thereof respectively protrude from the two clamping blocks.

Wherein, the medicine infusion system further includes a sleeve, which is sleeved on the two clamp arms of the upper joint, and the inner side wall of the two protrusions protrudes from the two protrusions, and the two protrusions abut against the outer sides of the two clamp arms. , And its position corresponds to the position of the clamping block of the two clamping arms.

Wherein, when the needle-free connector has not been combined with the movable closed joint, the two convex bodies provide a force to the two clamp arms, so that the bottom of the clamp block of the two clamp arms abuts on the top of the middle joint, And the part of the two clamping arms located below the clamping block firmly clamps the middle joint by the force.

Wherein, after the combination of the needle-free connector and the middle joint is completed, before the middle joint and the upper joint begin to be assembled, the sleeve moves in the direction of the middle joint and disengages from the two clamp arms until the two convex Until the body abuts the two bosses, the two clamping arms can be expanded outward at this time, so that the clamping block of the two clamping arm is separated from the top of the middle joint, and the part of the two clamping arm located below the clamping block is no longer Clamp the middle connector.

Wherein, when the middle joint and the upper joint start to be combined, the upper joint moves in the direction of the middle joint, and the two clamping arms are slid in the two long grooves until the clamping blocks of the two clamping arms abut against the Up to the screw connection part of the needle-free connector, at this time, the part of the two clamp arms located below the clamping block clamps the screw connection part of the needle-free connector.

The effect of the present invention is that it can be universally used for syringes with connection ends (Luer connectors) according to ISO 594-1 and 594-2, and connection ends (Luer connectors) according to ISO 594-1 and 594-2. Closed joints and movable closed joints designed by different brands.

Secondly, the present invention can adjust the atmospheric pressure of the sealed bottle or the sealed bag, so that the toxic medicine can be easily extracted from the sealed bottle or the sealed bag, and the toxic medicine can be prevented from remaining on the outer surface of the needle-free connector, and the toxic gas will not pass through. Pin connector while floating in the outer space.

Furthermore, the present invention can prevent toxic drugs from entering the balloon through the barrier. The structure of the barrier is simple, small in size, low in cost, and not easy to damage, and the user can also observe the wrong way of taking the drug and hurry up. Amended.

In addition, the elastomer of the needle-free connector can completely scrape the toxic drugs on the outer surface of the cylinder of the upper connector.

In addition, the user can remove the balloon or the entire set of pressure relief devices to access or formulate non-toxic drugs.

In addition, the sheath can be prevented from being exposed by the sheath, thereby achieving the effect of protecting the pillar.

In addition, the force of clamping the middle joint can be raised by the sleeve, so that the clamping block is not easy to detach from the top of the middle joint.

Furthermore, the small-diameter portion of the needle-free connector can be connected to the infusion tube in the form of a Y-shape or a T-shape, so that after the medicine is taken, the invention can be connected to the infusion tube, and the medicine is passed through the infusion tube and with it. A connected intravenous system enters the body.

10‧‧‧ Ontology

351, 351 ", 351 '' '‧‧‧ lower passage

11‧‧‧Screw joint

36, 36'‧‧‧ elastomer

111‧‧‧shaft hole

361, 361'‧‧‧ slit

12‧‧‧ Piercing Department

362, 362'‧‧‧ base

121‧‧‧ Tip

3621'‧‧‧Slit

13‧‧‧ the first channel

363, 363'‧‧‧ folds

14‧‧‧Second Channel

364, 364'‧‧‧ tube

15‧‧‧ Buckle

365‧‧‧retaining wall

16‧‧‧large diameter hole

37, 37 '' '‧‧‧ bulkhead

17‧‧‧ Small diameter hole

40, 40'‧‧‧ mobile closed joint

20‧‧‧ Pressure Relief Device

41, 41'‧‧‧ middle joint

21‧‧‧ Connection Structure

411‧‧‧container

211‧‧‧link

412‧‧‧clamp

2111‧‧‧Socket

4121‧‧‧Clamp

21111‧‧‧Shaft hole

413‧‧‧arc block

2112‧‧‧Circle

414‧‧‧carriage

21121‧‧‧Shaft hole

4141‧‧‧Shaft hole

21122‧‧‧Slot

415‧‧‧ convex

21123‧‧‧Arc gap

4151, 4151'‧‧‧ long slot

2113‧‧‧Screw joint

416‧‧‧Limit block

21131‧‧‧Shaft hole

417‧‧‧Ditch

212‧‧‧ balloon assembly

418'‧‧‧Boss

2121‧‧‧ Trail

42, 42'‧‧‧ Upper connector

21211‧‧‧Thread hole

421‧‧‧Screw joint

2122‧‧‧Large diameter section

4211‧‧‧Shaft hole

21221‧‧‧Shaft hole

422‧‧‧ cylinder

2123‧‧‧Funnel Department

4221‧‧‧Shaft hole

21231‧‧‧ Funnel-shaped opening

4222‧‧‧side opening

2124‧‧‧ Front Catheter

423, 423'‧‧‧ clip arm

21241‧‧‧Front access

4231, 4231'‧‧‧ clamp block

2125‧‧‧ rear catheter

424‧‧‧Top wall

21251‧‧‧ rear channel

425‧‧‧ ring wall

2126‧‧‧ Bezel

4251‧‧‧Vertical groove

213‧‧‧ Collar

4252‧‧‧Chute

22‧‧‧ balloon

426‧‧‧Room

221‧‧‧ open end

43‧‧‧ plug

23‧‧‧ compartment

431‧‧‧shaft hole

30, 30 ', 30 ", 30' '', 30 '' '' ‧‧‧pinless connectors

432‧‧‧Slit

301‧‧‧accommodation space

433‧‧‧Shaft

302‧‧‧Class Division

434‧‧‧Ring

303 "‧‧‧Assembly Department

4341‧‧‧Gully

304 "‧‧‧plug

50‧‧‧ syringe

3041 "‧‧‧Slit

51‧‧‧Connector

31‧‧‧Screw joint

511‧‧‧catheter

311‧‧‧shaft hole

60‧‧‧closed joint

32, 32 "‧‧‧large diameter section

61‧‧‧Connector

33, 33 ", 33 '' ', 33' '' '

70‧‧‧ sheath

331‧‧‧screw holes

80‧‧‧ sleeve

332 '' ', 332' '' '‧‧‧ branch line

81‧‧‧ convex

34, 34 ', 34 "‧‧‧ up catheter

100‧‧‧ sealed bottle

341, 341 "‧‧‧ on the channel

101‧‧‧ top margin

342‧‧‧Side hole

102‧‧‧Sealing

343'‧‧‧Ring Block

200, 201‧‧‧ infusion tubes

35‧‧‧ down catheter

FIG. 1 is a perspective view of a first embodiment of a pharmaceutical infusion system of the present invention.

FIG. 2 is an exploded view of the first embodiment of the pharmaceutical infusion system of the present invention.

FIG. 3 is a perspective view of a body, a pressure relief device, and a needle-free connector of a first embodiment of a pharmaceutical infusion system of the present invention.

FIG. 4 is another perspective view of the body, the pressure relief device, and the needle-free connector of the first embodiment of the pharmaceutical infusion system of the present invention.

FIG. 5 is an exploded view of the body, the pressure relief device, and the needle-free connector of the first embodiment of the pharmaceutical infusion system of the present invention.

6 is a cross-sectional view of a body, a pressure relief device, and a needle-free connector of a first embodiment of a pharmaceutical infusion system of the present invention.

FIG. 7 is a perspective view of the needle-free connector and the movable closed joint of the first embodiment of the pharmaceutical infusion system of the present invention, wherein the needle-free connector has not been combined with the movable closed joint.

FIG. 8 is an exploded view of the needle-free connector and the movable closed joint of the first embodiment of the medicine infusion system of the present invention.

Fig. 9A is a sectional view taken along the line A-A of Fig. 7.

Fig. 9B is a B-B sectional view of Fig. 7.

FIG. 10A is a cross-sectional view of the combination of the needle-free connector and the middle joint of FIG. 9A.

FIG. 10B is a cross-sectional view of the combination of the needle-free connector and the middle joint of FIG. 9B.

FIG. 11 is a cross-sectional view of the combination of the needle-free connector and the movable closed joint of FIG. 9A.

FIG. 12 is a schematic diagram of adding medicine in the first embodiment of the medicine infusion system of the present invention.

FIG. 13 is a schematic diagram of medicine taking of the first embodiment of the medicine infusion system of the present invention.

FIG. 14 is a cross-sectional view of a second embodiment of the pharmaceutical infusion system of the present invention.

15 is a schematic diagram of a third embodiment of the needle-free connector set of the pharmaceutical infusion system of the present invention provided at the connection end of the closed joint, wherein the syringe and the closed joint are combined.

FIG. 16 is a schematic view of a third embodiment of the needle-free connector set of the pharmaceutical infusion system of the present invention provided at the connection end of the closed joint, wherein the syringe and the closed joint are separated. FIG. 17 is a perspective view of a fourth embodiment of the pharmaceutical infusion system of the present invention.

18 is a cross-sectional view of a fourth embodiment of the pharmaceutical infusion system of the present invention.

FIG. 19 is a perspective view of a fifth embodiment of the pharmaceutical infusion system of the present invention.

FIG. 20 is a cross-sectional view of a fifth embodiment of the pharmaceutical infusion system of the present invention.

21 is a cross-sectional view of a needle-free connector of a sixth embodiment of the pharmaceutical infusion system of the present invention.

FIG. 22 is an exploded view of the needle-free connector of the sixth embodiment of the pharmaceutical infusion system of the present invention.

Fig. 23 is a side view of a sleeve of a seventh embodiment of the pharmaceutical infusion system of the present invention.

Fig. 24 is another angled side view of the sleeve of the seventh embodiment of the pharmaceutical infusion system of the present invention.

25 is a cross-sectional view of a sleeve of a seventh embodiment of the pharmaceutical infusion system of the present invention.

FIG. 26 is a cross-sectional view of a needle-free connector, a movable closed joint and a sleeve of a seventh embodiment of the pharmaceutical infusion system of the present invention, wherein the needle-free connector has not been combined with the movable closed joint.

27 is a cross-sectional view of a combination of a needle-free connector and a middle joint of a seventh embodiment of the pharmaceutical infusion system of the present invention.

FIG. 28 is a cross-sectional view of a combination of a needle-free connector and a movable-type closed joint according to a seventh embodiment of the pharmaceutical infusion system of the present invention.

FIG. 29 is a perspective view of a needle-free connector of an eighth embodiment of the pharmaceutical infusion system of the present invention.

FIG. 30 is a cross-sectional view of a needle-free connector of an eighth embodiment of the pharmaceutical infusion system of the present invention.

FIG. 31 is a perspective view of a needle-free connector of a ninth embodiment of the pharmaceutical infusion system of the present invention.

32 is a cross-sectional view of a needle-free connector of a ninth embodiment of a pharmaceutical infusion system of the present invention.

The following describes the embodiments of the present invention in more detail with reference to the drawings and element symbols, so that those skilled in the art can implement them after studying this specification.

Please refer to FIG. 1 to FIG. 9B. FIG. 1 is a perspective view of a first embodiment of a pharmaceutical infusion system of the present invention. FIG. 2 is an exploded view of a first embodiment of a pharmaceutical infusion system of the present invention. A perspective view of the body and the pressure relief device of the first embodiment of the infusion system. FIG. 4 is a perspective view of the body and the pressure relief device of the first embodiment of the pharmaceutical infusion system of the present invention from another angle. An exploded view of the body and the pressure relief device of the first embodiment of the infusion system. FIG. 6 is a cross-sectional view of the body and the pressure relief device of the first embodiment of the medicine infusion system of the present invention. FIG. 7 is a drug infusion system of the present invention. Perspective view of the first embodiment of the needle-free connector and the movable closed joint, wherein the needle-free connector has not been combined with the movable closed joint, FIG. 8 is a needle-free connector of the first embodiment of the pharmaceutical infusion system of the present invention FIG. 9A is a cross-sectional view taken along the line AA of FIG. 7 and FIG. 9B is a cross-sectional view taken along the line BB of FIG. 7. The invention provides a medicine infusion system, which includes a body 10, a pressure relief device 20, and a needle-free connector 30.

Referring to FIGS. 3 to 6, the body 10 includes a screw connection portion 11 and a puncture portion 12, and a first channel 13 and a second channel 14 are opened. A shaft hole 111 is defined in the screw connection portion 11 of the main body 10. The bottom end of the puncture portion 12 has a tip 121. The first channel 13 extends axially from the puncture portion 12 and penetrates the bottom end of the puncture portion 12. The second channel 14 extends axially from the puncture portion 12 and communicates with the shaft hole 111 of the screw connection portion 11 of the body 10 and penetrates the bottom end of the puncture portion 12. More specifically, the tip 121 of the puncture portion 12 is located at the center of the bottom end of the puncture portion 12, and the first channel 13 and the second channel 14 both extend linearly at the eccentric position of the puncture portion 12, so the first channel 13 and the second channel The bottom end openings of 14 are located on both sides of the tip 121. The diameter of the second channel 14 is larger than the diameter of the first channel 13 and smaller than the diameter of the shaft hole 111 of the screw joint 11 of the body 10.

Please refer to FIGS. 3 to 6. The pressure relief device 20 includes a connection structure 21, a balloon 22 and a partition 23. The connecting structure 21 is detachably provided on the main body 10 and a first channel is opened. The flow channel communicates with the first channel 13 of the main body 10. The balloon 22 is detachably provided on the connection structure 21. The interlayer 23 is a filter paper or a filter membrane. It is composed of waterproof and breathable material for the flow channel, and has the ability to prevent the passage of liquid and the passage of gas. In other words, liquid cannot pass through the interlayer 23 and gas can pass through the interlayer 23.

Please refer to FIGS. 7 to 9B. The needle-free connector 30 includes a screw connection portion 31, a large diameter portion 32, a small diameter portion 33, an upper conduit 34, a lower conduit 35, and an elastic body 36. The screw connection portion 31 of the needle-free connector 30 is disposed on the top of the large-diameter portion 32 of the needle-free connector 30 and defines a shaft hole 311. The large-diameter portion 32 of the needle-free connector 30 is disposed between the screw connection portion 31 of the needle-free connector 30 and the small-diameter portion 33 of the needle-free connector 30 and forms a receiving space 301 together with a partition plate 37. In more detail, the screw-connected portion 31 and the large-diameter portion 32 of the needle-free connector 30 are not integrally formed, but are manufactured separately and then fixed by technology such as ultrasonic welding; the large-diameter portion of the needle-free connector 30 32 and the small-diameter portion 33 are integrally formed. The accommodating space 301 of the large-diameter portion 32 of the needle-free connector 30 communicates with the shaft hole 311 of the screw connection portion 31 of the needle-free connector 30. The elastic body 36 is disposed in the accommodating space 301, and extends to the shaft hole 311 of the screw connection portion 31 of the needle-free connector 30, and a slit 361 is opened on the top thereof. The upper duct 34 is disposed inside the elastic body 36 and defines an upper passage 341. The small-diameter portion 33 of the needle-free connector 30 and the partition plate 37 together define a screw hole 331. The lower duct 35 integrally extends from the partition plate 37 to the screw hole 331 of the small-diameter portion 33 of the needle-free connector 30 and defines a lower channel 351, which further extends through the partition plate 37. The first side portion 302 is formed at the contact between the outer side surface of the large-diameter portion 32 of the needle-free connector 30 and the outer side surface of the small-diameter portion 33 of the needle-free connector 30. The screwed portion 11 of the body 10 is screwed into the screw hole 331 of the small diameter portion 33 of the needle-free connector 30, so that the lower pipe 35 of the needle-free connector 30 is inserted into the shaft hole 111 of the screwed portion 11 of the body 10. , As shown in Figure 12.

The group of needle-free connectors 30 is provided in a movable closed joint 40 (see the first embodiment shown in FIG. 1 to FIG. 9B); A connection end 51 (see the second embodiment shown in FIG. 14) or a connection end 61 of a closed joint 60 (see the third embodiment shown in FIGS. 15 and 16).

Further, referring to FIG. 7 to FIG. 9B, in the first embodiment, the movable-type closed joint 40 includes a middle joint 41 and an upper joint 42. The middle joint 41 surrounds a receiving slot 411 and includes two clips 412. The upper joint 42 includes a screwing portion 421, a post 422, and two clamping arms 423. A shaft hole 4211 is defined in the screw connection portion 421 of the upper joint 42. The cylinder 422 has a shaft hole 4221 and a side opening 4222. The shaft hole 4221 of the cylinder 422 communicates with the shaft hole 4211 of the screw joint 421 of the upper joint 42. The side opening 4222 of the cylinder 422 and the shaft hole 4221 of the cylinder 422 Communicate. The two clamping arms 423 surround the post 422. When the needle-free connector 30 has not been combined with the movable closed joint 40, the needle-free connector 30 is far from the middle joint 41.

Please refer to FIGS. 10A and 10B. FIG. 10A is a cross-sectional view of the combination of the needle-free connector and the middle joint of FIG. 9A, and FIG. 10B is a cross-sectional view of the combination of the needle-free connector and the middle joint of FIG. 9B. When the needle-free connector 30 and the middle connector 41 start to be combined, the needle-free connector 30 moves inside the receiving groove 411 of the middle connector 41 until the two clips 412 of the middle connector 41 clamp the first-part portion of the needle-free connector 30. Until 302.

Please refer to FIG. 11, which is a cross-sectional view of the combination of the needle-free connector and the movable closed joint of FIG. 9A. When the middle joint 41 and the upper joint 42 start to be combined, the upper joint 42 moves in the direction of the middle joint 41, the post 422 of the upper joint 42 is stretched out and passes through the slit 361 of the elastic body 36 of the needle-free connector 30 to enter the elasticity. The body 36 pushes the upper pipe 34 downward until the two clamping arms 423 of the upper joint 42 clamp the screwing portion 31 of the needle-free connector 30.

Thus, the needle-free connector 30 of the present invention is not only simple in structure and low in cost, but also can be universally used for syringes 50 having a connection end 51 (Luer connector) in accordance with ISO 594-1 and 594-2, ISO 594-1 and 594-2 stipulate the closed joint 60 of the connection end 61 (Luer joint) and the movable closed joint 40 designed by different brands.

Please refer to FIG. 12. FIG. 12 is a schematic diagram of adding medicine in the first embodiment of the medicine infusion system of the present invention. Some toxic drugs must be dissolved or diluted before use. Withdraw the toxic drug from a container (not shown). Next, the screwing portion 421 of the upper joint 42 of the movable closing joint 40 is screwed to the connecting end 51 of the syringe 50, and the catheter 511 in the connecting end 51 of the syringe 50 is inserted into the upper joint 42 of the movable closing joint 40. In the shaft hole 4211 of the screw connection portion 421. Then, based on the principle that the pharmaceutical infusion system of the present invention is on top and a sealed bottle 100 or a sealed bag (not shown) is on the bottom, one side of the sealed bottle 100 or a sealed bag is fastened by a fastener 15 of the body 10 The edge 101 is used to pierce one end 102 of the sealed bottle 100 or the sealed bag from top to bottom by the tip 121 of the puncture portion 12 of the body 10. Finally, a piston (not shown) is used to push the toxic drug in the syringe 50 from above to the tube 511 passing through the connecting end 51 of the syringe 50, so that the toxic drug passes through the cylinder of the upper connector 42 in order from top to bottom. Shaft hole 4221 and side opening 4422 of 422, upper channel 341 of upper conduit 34 and lower channel 351 of lower conduit 35 of needle-free connector 30, shaft hole 111 of screwed portion 11 of body 10, and second hole of body 10 The channel 14 is then injected into the sealed bottle 100 or sealed bag to complete the correct dosing action. At this time, the atmospheric pressure in the sealed bottle 100 or the sealed bag is greater than the external atmospheric pressure, so that the toxic gas in the sealed bottle 100 or the sealed bag sequentially passes through the first channel 13 of the body 10 and the connection structure 21 of the pressure relief device 20 Flow channel, and smoothly pass through the partition 23, and then enter the balloon 22 to achieve the effect of pressure relief, so that the atmospheric pressure in the sealed bottle 100 or the sealed bag is maintained the same as the outside world, and the sealed bottle 100 or the sealed bag is avoided Some of the toxic drugs will pass through the needle-free connector 30 in a gas form or by atomization, so no toxic drugs will remain on the outer surface of the needle-free connector 30, and toxic gases will not pass through the needle-free connector 30. Floating in the outer space. As a result, the skin of medical staff does not come into contact with toxic drugs and does not inhale toxic gases into the lungs.

Please refer to FIG. 13, which is a schematic diagram of medicine taking of the first embodiment of the medicine infusion system of the present invention. When the user wants to remove the toxic drug from the sealed bottle 100 or the sealed bag, the piston is first moved to the innermost side of the syringe 50 to evacuate the air in the syringe 50, and then the upper joint 42 of the movable closure joint 40 is The screwing portion 421 is screwed on the connecting end 51 of the syringe 50. The tube 511 is inserted into the shaft hole 4211 of the screw connection portion 421 of the upper joint 42 of the movable-type closed joint 40. Next, based on the principle that the dispensing infusion system of the present invention is down and the sealed bottle 100 or the sealed bag is up, one side of the sealed bottle 100 or the top edge 101 of the sealed bag is fastened by the buckle 15 of the body 10 while the The tip 121 of the puncture portion 12 pierces the sealed bottle 100 or the sealed bag 102 from the bottom up. Then, the piston is pulled from the inside of the syringe 50 to the outside, so that the toxic drug in the sealed bottle 100 or the sealed bag passes through the second channel 14 of the body 10 and the shaft hole 111 of the screwed portion 11 of the body 10 in order from top to bottom. , The lower channel 351 of the lower catheter 35 and the upper channel 341 of the upper catheter 34 of the needle-free connector 30, the side opening 4222 and the shaft hole 4221 of the cylinder 422 of the upper joint 42, and the catheter 511 of the connection end 51 of the syringe 50, It is then injected into the syringe 50. At this time, the atmospheric pressure in the sealed bottle 100 or the sealed bag is smaller than the external atmospheric pressure, so that the clean gas in the balloon 22 sequentially passes through the flow channel of the connection structure 21 of the pressure relief device 20 and the first channel 13 of the body 10, And smoothly pass through the partition 23, and then enter the sealed bottle 100 or the sealed bag, so as to achieve the same effect as maintaining the atmospheric pressure in the sealed bottle 100 or the sealed bag with the outside atmospheric pressure, and the toxic drugs are easily removed from the sealed bottle 100 or Draw out from the sealed bag.

Through the above-mentioned correct method of adding and taking medicine, the toxic medicine will not enter the balloon 22 through the first channel 13 of the body 10.

However, some medical personnel lacking in concept will set the dispensing infusion system of the present invention down and the sealed bottle 100 or sealed bag on the top when adding medicine, which will cause the toxic drugs in the sealed bottle 100 or sealed bag to easily go up. The flow channel of the connection structure 21 of the pressure relief device 20 is entered through the first channel 13 of the body 10 below. At this time, the toxic drug will be blocked by the barrier 23 and cannot pass through the barrier 23 to prevent the toxic drug from entering the balloon 22. In addition, the partition layer 23 also has the advantages of simple structure, small size, low cost, and easy damage. The user can also observe from the compartment 23 that the toxic drug remains in the flow channel of the connection structure 21 of the pressure relief device 20 or the first channel 13 of the main body 10, and can find the wrong way of taking the drug and quickly fix it.

During the process of taking the medicine, the outer surface of the cylinder 422 of the upper joint 42 will be stained with toxic drugs. At this time, the user can use the syringe 50 to pull the upper joint 42 to move away from the middle joint 41, so that the column of the upper joint 42 When the body 422 is detached from the elastic body 36 of the needle-free connector 30, the elastic body 36 of the needle-free connector 30 can completely scrape off the toxic drugs on the outer surface of the cylinder 422 of the upper connector 42, so that the upper connector 42 After the pillar body 422 is detached from the elastic body 36 of the needle-free connector 30, the outer surface of the pillar body 422 is free from any toxic drug residues, thereby preventing the toxic drugs from remaining on the outer surface of the needle-free connector 30. As a result, the skin of medical staff does not come into contact with toxic drugs.

Preferably, the material of the elastic body 36 of the pin-free connector 30 is silicon rubber or rubber. With this, after the post 422 of the upper connector 42 is stretched and passes through the slit 361 of the elastic body 36 of the needle-free connector 30, the elastic body 36 of the needle-free connector 30 can tightly cover the post of the upper connector 42. The body 422 is located at the slit 361 portion of the elastic body 36 of the needle-free connector 30, so as to prevent the user from leaking toxic drugs and toxic gases from the slit 361 of the elastic body 36 of the needle-free connector 30 when taking medicine. In addition, after the post 422 of the upper connector 42 is detached from the elastic body 36 of the needle-free connector 30, the slit 361 of the elastic body 36 of the needle-free connector 30 will quickly return to the original closed state, avoiding the upper The post 422 of the connector 42 is exposed, and at the same time, toxic drugs and toxic gases are prevented from leaking from the slits 361 of the elastic body 36 of the needle-free connector 30.

In this embodiment, the movable-type closed joint 40 includes a plug body 43, as shown in FIGS. 7 to 9B. The plug body 43 is disposed in the receiving groove 411 of the middle joint 41 and defines a shaft hole 431 and a slit 432. Specifically, the middle joint 41 has two arc-shaped blocks 413 and a carrier 414; the two arc-shaped blocks 413 are provided on the inner wall of the middle joint 41 near the top end of the middle joint 41; the carrier 414 is disposed on the two arcs Below the block 413, an outer side thereof is in contact with an inner side wall of the middle joint 41, and a shaft hole 4141 is opened. The plug body 43 has a shaft portion 433 and a ring portion 434; the bottom of the shaft portion 433 of the plug body 43 passes through the shaft hole 4141 of the carrier 414, and the shaft hole 431 of the plug body 43 is opened in the shaft portion 433 of the plug body 43 and penetrates the top thereof The slit 432 of the plug body 43 is opened on the shaft portion 433 of the plug body 43 The ring portion 434 of the plug body 43 surrounds the shaft portion 433 of the plug body 43 and a ring groove 4341 is recessed on the outer side. The bottom of the ring portion 434 of the plug body 43 abuts the upper surface of the carrier 414. The arc-shaped block 413 is provided in the ring groove 4341 of the ring portion 434 of the plug body 43.

When the needle-free connector 30 has not been combined with the movable closed joint 40, the post 422 of the upper joint 42 is located in the shaft hole 431 of the plug 43, as shown in FIGS. 9A and 9B. When the two clips 412 of the middle joint 41 clamp the step portion 302 of the needle-free connector 30, the bottom of the shaft portion 433 of the plug 43 abuts against the top of the elastic body 36 of the needle-free connector 30, as shown in FIG. 10A and Figure 10B. When the middle joint 41 and the upper joint 42 of the movable closed joint 40 start to be combined, the upper joint 42 moves in the direction of the middle joint 41, and the cylinder 422 of the upper joint 42 is sequentially opened and passes through the shaft portion 433 of the plug 43 The slit 432 and the slit 361 of the elastic body 36 of the needle-free connector 30 enter the interior of the elastic body 36, as shown in FIG. 11. Thereby, the plug body 43 and the elastic body 36 of the needle-free connector 30 can provide a dual effect of preventing leakage of toxic drugs and toxic gases.

Preferably, the material of the plug body 43 is silicon rubber or rubber. With this, after the post 422 of the upper joint 42 is stretched and passes through the slit 432 of the plug 43, the slit 432 of the plug 43 can tightly cover the post 422 of the upper joint 42 located in the narrow of the plug 43. The slit 432 prevents the user from leaking toxic drugs and toxic gases from the slit 432 of the plug 43 when taking the medicine. In addition, after the post 422 of the upper joint 42 is detached from the plug 43, the slit 432 of the plug 43 will quickly return to the original closed state, preventing the post 422 of the upper joint 42 from being exposed, and preventing toxic drugs And toxic gas leaks from the slit 432 of the plug body 43. This technical feature can further improve the effect of preventing the leakage of toxic drugs and toxic gases if it can be matched with the elastomer 36 of the needle-free connector 30 made of silicone or rubber.

Some toxic drugs do not generate toxic gases. The user can remove the balloon 22 from the connection structure 21. Therefore, when taking medicine or adding medicine, clean air can enter and exit the sealed bottle 100 or sealed bag through the partition 23, and at the same time, toxic drugs can still be blocked by the partition 23 without seeping from the connection structure 21.

Sometimes when the non-toxic medicine is taken or formulated, the presence or absence of the balloon 22 does not affect the operation. Because the balloon 22 of the present invention is detachable, the user can individually remove the balloon 22 from the connection structure 21 or remove the entire set of pressure relief devices 20 from the body 10 in order to access or Formulate non-toxic drugs.

Please refer to FIG. 6 again. In this embodiment, the body 10 is provided with a large-diameter hole 16 extending radially and a small-diameter hole 17 extending radially. The small-diameter hole 17 communicates with the first channel 13 and the large-diameter hole 16 between.

Please refer to FIGS. 1 to 6 again. In this embodiment, the connection structure 21 of the pressure relief device 20 includes a connecting member 211, a balloon assembly 212, and a set of rings 213.

The connecting member 211 includes a plug-in portion 2111, a ring body 2112, and a screw connection portion 2113. The insertion portion 2111 is inserted into the large-diameter hole 16 and defines a shaft hole 21111. The ring body 2112 is provided between the inserting portion 2111 and the screwing portion 2113 of the connecting member 211 and defines a shaft hole 21121 and an insert groove 21122. The shaft hole 21121 of the ring body 2112 communicates with the insert groove 21122, and the partition 23 is provided in the insert A part of the groove 21122 is located in the shaft hole 21121 of the ring body 2112. The screwing portion 2113 of the connecting member 211 defines a shaft hole 21131.

The balloon assembly 212 includes a small diameter portion 2121, a large diameter portion 2122, a funnel portion 2123, a front duct 2124, and a rear duct 2125. The small-diameter portion 2121 of the balloon assembly 212 and a baffle plate 2126 form a screw hole 21211 together, and the screwing portion 2113 of the connecting member 211 is screwed to the screw hole 21211 of the small-diameter portion 2121 of the balloon assembly 212. The large-diameter portion 2122 of the balloon assembly 212 is disposed at an end of the small-diameter portion 2121 of the balloon assembly 212 away from the connecting member 211 and defines a shaft hole 21221 together with the baffle 2126. The funnel portion 2123 is disposed at an end of the large-diameter portion 2122 of the balloon assembly 212 away from the small-diameter portion 2121 of the balloon assembly 212 and defines a funnel-shaped opening 21231. The front duct 2124 integrally extends from the baffle 2126 to the screw hole 21211 of the small diameter portion 2121 of the balloon assembly 212, is inserted into the shaft hole 21131 of the screw connection portion 2113 of the connecting member 211, and opens a front channel 21241. The rear duct 2125 extends integrally from the baffle 2126 to the shaft hole of the large diameter portion 2122 of the balloon assembly 212 21221 and the funnel-shaped opening 21231 of the funnel part 2123 and a rear passage 21251 are opened. An open end 221 of the balloon 22 is sleeved on the outer side of the rear duct 2125.

Axial hole 21111 of connector portion 2111 of connector 211, axial hole 21121 of ring body 2112 of connector 211, front channel 21241 of front duct 2124 of balloon assembly 212, and rear channel of rear duct 2125 of balloon assembly 212 21251 is collectively defined as the runner.

The collar 213 is sleeved on the outer periphery of the open end 221 of the balloon 22, and fixes the open end 221 of the balloon 22 between the outer side surface of the rear duct 2125 and the inner side wall of the large-diameter portion 2122 of the balloon assembly 212. Thereby, the balloon 22 can be easily fixed to the rear catheter 2125 through the collar 213, which is easy to assemble and has a good fixing effect, and the balloon 22 will not easily fall off.

When the user wants to detach the balloon 22 from the connecting structure 21, the collar 213 and the balloon 22 can be directly removed from the outer side of the rear catheter 2125, which is very convenient.

When the user wants to remove the balloon 22 together with the connecting structure 21 from the body 10, the plugging portion 2111 can be directly removed from the large-diameter hole 16, and the operation is very simple.

When the toxic gas enters the balloon 22, the balloon 22 will gradually expand, and its outer surface will closely contact the funnel-shaped opening 21231 of the funnel portion 2123.

Preferably, at least a part of the embedded groove 21122 penetrates the outer peripheral surface of the ring body 2112 to form an arc-shaped slot 21123, and the partition layer 23 can enter and exit the embedded groove 21122 through the arc-shaped slot 21123, as shown in FIG. 5. This technical feature is convenient for the user to assemble and replace the partition 23.

Preferably, the size and shape of the partition layer 23 correspond to the size and shape of the embedded groove 21122. In this way, the wall surface of the partition layer 23 and the embedded groove 21122 is closely combined without any gaps, so as to prevent the toxic drug from leaking out.

Please refer to FIG. 7 to FIG. 9B again. In this embodiment, the two clips 412 are respectively disposed on two opposite sides of the outer peripheral surface of the middle joint 41. The middle joint 41 includes two convex portions 415, and the two convex portions 415 are respectively provided. Yu Zhongjie The outer peripheral surface of the head 41 is opposite to the other two sides and extends axially; each convex portion 415 defines a longitudinally extending long slot 4151. The top of the two long slots 4151 is open and the bottom is closed. The inner side communicates with the receiving slot 411. .

When the middle joint 41 and the upper joint 42 start to be combined, the upper joint 42 moves in the direction of the middle joint 41, and the two clamp arms 423 are slid in the two long grooves 4151, as shown in FIGS. 7 and 9A.

Please refer to FIG. 7 to FIG. 9B again. In this embodiment, the upper joint 42 has a top wall 424 and a ring wall 425, and the top wall 424 and the ring wall 425 together constitute a container 426. The screw connection portion 421 of the upper joint 42 is provided on the upper surface of the top wall 424. The pillar 422 is disposed on the lower surface of the top wall 424 and is located in the receiving chamber 426. The two opposite sides of the ring wall 425 are respectively provided with two vertical grooves 4251 passing through the bottom thereof. The width of the two vertical grooves 4251 is larger than the width of the two convex portions 415. The two clamping arms 423 are disposed on the lower surface of the top wall 424, respectively located in the two longitudinal grooves 4251, and the inner sides of the two clamping arms 4321 respectively protrude from the two clamping blocks 4231.

When the needle-free connector 30 has not been combined with the movable closed joint 40, the bottom of the clamp block 4231 of the two clamp arms 423 abuts against the top of the middle joint 41, and the two clamp arms 423 are located below the clamp block 4231. Clamp the middle joint 41 as shown in Figs. 7 to 10B. Even if the user accidentally touches the upper joint 42, the upper joint 42 will not easily move in the direction of the middle joint 41 because the bottom of the clamping block 4231 of the two clamping arms 423 abuts against the top of the middle joint 41. Before the needle-free connector 30 is combined with the movable closed joint 40, the post 422 passes through the slit 432 of the plug 43 and the slit 361 of the elastic body 36 of the needle-free connector 30.

When the middle joint 41 and the upper joint 42 start to be assembled, the two convex portions 415 are respectively slidably disposed in the two longitudinal grooves 4251 until the clamping block 4231 of the two clamping arms 423 abuts against the screwing portion 31 of the needle-free connector 30. So far, the portion of the two clamping arms 423 located below the clamping block 4231 clamps the screw connection portion 31 of the needle-free connector 30; as shown in FIG. 11.

Please refer to FIG. 7 to FIG. 9B again. In this embodiment, the middle joint 41 includes two limiting blocks 416, which are respectively disposed on two opposite sides of the outer peripheral surface of the middle joint 41 and are located on the two clips. 412 Up. Two opposite sides of the annular wall 425 are respectively provided with two sliding grooves 4252. The two sliding grooves 4252 do not penetrate the bottom of the annular wall 425, and the two limiting blocks 416 are respectively slidably disposed in the two sliding grooves 4252.

When the needle-free connector 30 has not been combined with the movable closed joint 40, the two limiting blocks 416 abut against the bottom ends of the two sliding grooves 4252.

When the two clamping arms 423 clamp the screw connection portion 31 of the needle-free connector 30, the two limiting blocks 416 abut against the lower surface of the top wall 424 of the upper joint 42.

Here, no matter how the upper joint 42 and the middle joint 41 move relative to each other, they will not easily disengage from each other.

Please refer to FIG. 7 to FIG. 9B again. In this embodiment, the two opposite sides of the outer peripheral surface of the middle joint 41 are respectively provided with two grooves 417 penetrating through the bottom thereof, and the two clips 412 extend axially from the two grooves, respectively. 417, and two inner blocks 4121 protrude from the inside.

When the needle-free connector 30 and the middle connector 41 start to be combined, the needle-free connector 30 moves to the inside of the receiving groove 411 of the middle connector 41 until the clamping block 4121 of the two clip bodies 412 clamps the step portion of the needle-free connector 30. Up to 302, as shown in Figs. 10A and 10B.

Please refer to FIG. 7 to FIG. 9B again. In this embodiment, the elastic body 36 of the needle-free connector 30 includes a base 362, a fold portion 363, and a barrel portion 364. The base 362 is hollow and abuts against the partition plate 37, and the inside thereof communicates with the lower channel 351. The corrugated portion 363 is integrally provided on the top of the base 362. The hollow tube portion 364 is integrally provided on the top of the hollow corrugated portion 363 and has the slit 361. The upper duct 34 has a retaining wall 365 that straddles the top opening of the upper channel 341 and divides the top opening of the upper channel 341 into two small holes. The cylinder 422 has two openings 4222. The cylinder 422 can abut against the retaining wall 365, and the medicine enters and exits the upper channel 341 through two small holes, so that the medicine enters and exits the shaft of the cylinder 422 through the two openings 4222 of the cylinder 422. hole 4221, as shown in Figures 12 and 13. Two sides of the bottom of the upper catheter 34 are provided with two-sided holes 342 through which drugs can enter and exit the upper channel 341 to allow drugs to enter and exit the lower channel 351, as shown in FIGS. 12 and 13.

Please refer to FIG. 17 and FIG. 18. FIG. 17 is a perspective view of a fourth embodiment of the medicine infusion system of the present invention, and FIG. 18 is a cross-sectional view of the fourth embodiment of the medicine infusion system of the present invention. The fourth embodiment provides a second form of the needle-free connector 30 ′, the structure of which is slightly different from that of the first embodiment. More specifically, the base 362 'of the elastic body 36' of the needleless connector 30 'of the fourth embodiment is not hollow, but has a slit 3621', so it is not in communication with the lower channel 351; 'Integrally provided on the top of the base 362'; the tube portion 364 'is not integrally formed with the fold portion 363', but is detachably provided on the base 362 'and covers the fold portion 363' inside. A ring seat 343 'extends laterally from the top of the upper pipe 34', and the top of the ring seat 343 'abuts against the wall surface of the tube portion 364'; the bottom of the upper pipe 34 'abuts against the base 362'. When the needle-free connector 30 has not been combined with the movable closed joint 40, the slit 3621 'of the base 362, the slit 361' of the barrel 364 ', and the slit 432 of the plug 43 are formed into three checkpoints to prevent toxic drugs Or the toxic gas is more outstanding than the first embodiment. When the post 422 pushes the upper duct 34 'down, the upper duct 34' can be stretched and passed through the slit 3621 'of the base 362'.

Please refer to FIG. 19 and FIG. 20. FIG. 19 is a perspective view of a fifth embodiment of the medicine infusion system of the present invention, and FIG. 20 is a cross-sectional view of the fifth embodiment of the medicine infusion system of the present invention. In the fifth embodiment, the pharmaceutical infusion system of the present invention further includes a sheath 70 provided in the receiving chamber 426, the top end of which is against the lower surface of the top wall 424 of the upper joint 42, and the bottom end is against the plug body 43, In addition, the pillar 422 is covered inside to prevent the pillar 422 from being exposed, thereby achieving the effect of protecting the pillar 422.

Please refer to FIG. 21 and FIG. 22. FIG. 21 is a cross-sectional view of a needle-free connector of a sixth embodiment of the drug infusion system of the present invention, and FIG. 22 is a needle-free connector of a sixth embodiment of the drug infusion system of the present invention. Exploded view. The sixth embodiment provides a third pinless connector 30 ", the structure of which is the same as that of the first embodiment. The pin-free connector 30 and the pin-free connector 30 'of the fourth embodiment are slightly different. In more detail, the pin-free connector 30 "of the sixth embodiment does not have a screw connection portion, but replaces the screw connection portion, the connection portion 303" and the large diameter portion with a connection portion 303 "with a smooth outer surface. 32 "is a one-piece structure. The large-diameter portion 32" and the small-diameter portion 33 "are not a one-piece structure, but are manufactured separately and then fixed by technology such as ultrasonic welding. It is worth mentioning that the needle-free connector 30 "of the sixth embodiment does not have an elastic body, and the upper conduit 34" protrudes upward from the top surface of the small-diameter portion 33 ", so that the upper channel 341" and the lower channel 351 "directly Interconnected. The sixth embodiment of the needle-free connector 30 "further includes a plug body 304", the plug body 304 "is provided inside the assembling portion 303", the bottom part abuts against the top surface of the upper duct 34 ", and a The slit 3041 ". The function and material of the plug body 304" are similar to the head of the elastic body 36 with the slit 361 (not shown in the figure), and will not be repeated here. Thereby, the plug body 43 and the plug body 304 "provide a double effect of preventing leakage of toxic drugs and toxic gases.

Please refer to FIGS. 23 to 28. FIG. 23 is a side view of the sleeve of the seventh embodiment of the pharmaceutical infusion system of the present invention, and FIG. 24 is another angle of the sleeve of the seventh embodiment of the pharmaceutical infusion system of the present invention Side view, FIG. 25 is a sectional view of a sleeve of a seventh embodiment of the pharmaceutical infusion system of the present invention, and FIG. 26 is a needle-free connector, a movable closed joint and a sleeve of the seventh embodiment of the pharmaceutical infusion system of the present invention A cross-sectional view of a cartridge, in which a needle-free connector has not been combined with a movable closed joint. FIG. 27 is a cross-sectional view of a combination of a needle-free connector and a middle joint of a seventh embodiment of the pharmaceutical infusion system of the present invention, and FIG. 28 is the present invention. Sectional view of a seventh embodiment of a needle-free connector and a movable closed joint of a pharmaceutical infusion system. The seventh embodiment uses a needle-free connector 30 ". The structure of the middle joint 41 'is slightly different from the middle joint 41 of the first embodiment and further includes a sleeve 80. Further, the middle joint 41' Two longitudinally extending long grooves 4151 'are provided on the other two opposite sides of the outer peripheral surface; the middle joint 41' includes two bosses 418 ', and the two bosses 418' approach the two long grooves 4151 'from the outer side of the middle joint 41', respectively. The bottom wall extends laterally. The width of the two longitudinal grooves 4251 is equal to the width of the two bosses 418 '. The sleeve 80 is sleeved on the two clamp arms 423' of the upper joint 42 ', and its The inner side wall protrudes two convex bodies 81; the two convex bodies 81 abut against the outer side surface of the two clamping arms 423 ', and their positions correspond to the positions of the clamping blocks 4231' of the two clamping arms 423 '.

As shown in FIG. 26, when the needle-free connector 30 "has not been combined with the movable closed joint 40 ', the two convex bodies 81 provide a force to the two clamping arms 423', so that the clamping blocks of the two clamping arms 423 ' The bottom of 4231 'abuts against the top of the middle joint 41', and the portion of the two clamping arms 423 'located below the clamping block 4231' firmly clamps the middle joint 41 'by the force. Here, the sleeve 80 The clamping force of the two clamping arms 423 'can be increased, so that the two clamping arms 423' can be clamped more tightly, and the clamping block 4231 'of the two clamping arms 423' cannot be easily disengaged. The top of the middle joint 41 '.

As shown in FIG. 27, after the combination of the needle-free connector 30 "and the middle joint 41 'is completed, before the middle joint 41' and the upper joint 42 'start to be combined, the sleeve 80 moves in the direction of the middle joint 41' and is disengaged. The two clamping arms 423 'until the two convex bodies 81 abut against the two bosses 418'. At this time, the two clamping arms 423 'can be expanded outward, so that the clamping blocks 4231' of the two clamping arms 423 'are disengaged. The top of the middle joint 41 ', and the part of the two clamping arms 423' below the clamping block 4231 'no longer clamps the middle joint 41'. It is worth mentioning that at this time, the sleeve 80 will also limit the middle joint 41 ' Therefore, the two clips of the middle joint 41 'cannot be expanded outward, and thus cannot be separated from the needle-free connector 30 ".

As shown in FIG. 28, when the middle joint 41 'and the upper joint 42' start to be combined, the upper joint 42 'moves toward the middle joint 41', and the two clamp arms 423 'are slid in the two long grooves 4151' until The two clamping arms 423 'of the two clamping arms 423' abut against the assembling portion 303 "of the pinless connector 30" (if used in the pinless connector 30, they abut against the screwing portion 31) until this time The part of the two clamping arms 423 'located below the clamping block 4231' clamps the assembly portion 303 "of the pin-free connector 30" (if used in the pin-free connector 30, it abuts against the screw connection portion 31).

After there is no danger of detachment during the dosing or taking action, the upper connector 42 'and the sleeve 80 must be moved back to the initial state when the needle-free connector 30 "has not been combined with the movable closed connector 40'. Start position, as shown in Figure 26. In this way, the two clips of the middle joint 41 'are no longer restricted by the sleeve 80, so that they can be deployed outward to disengage the needle-free connector 30 ". As a result, the needle-free connector 30" is no longer centered The two clips of the connector 41 ′ are clamped, so as to be able to move back to the initial position when the needle-free connector 30 ″ has not been combined with the movable closed connector 40 ′, as shown in FIG. 26.

Please refer to FIGS. 29 and 30. FIG. 29 is a perspective view of the needle-free connector of the eighth embodiment of the drug infusion system of the present invention, and FIG. 30 is a view of the needle-free connector of the eighth embodiment of the drug infusion system of the present invention. Sectional view. The eighth embodiment differs from the first to seventh embodiments in that the structure of the small diameter portion 33 '' 'of the needle-free connector 30' '' is slightly different. Further, the outside of the small-diameter portion 33 '' 'has a branch pipe 332' '' extending laterally upward, so that the small-diameter portion 33 '' 'is Y-shaped; the lower passage 351' '' runs directly through the small diameter Part 33 '' ', so the small diameter part 33' '' has the function of a downcomer directly, so the needle-free connector 30 '' 'does not need to have a downcomer and a partition, and the small diameter part 33' '' does not need to form a screw hole. After the user completes the medicine taking action, the movable closed joint 40 and the syringe 50 are first removed from the needle-free connector 30 '' '. Then, a set of movable type closed joints 40 is set on the pin-free connector 30 '' '. Next, one infusion tube 200 is inserted in the lower channel 351 '' 'of the small diameter portion 33' '', and the other infusion tube 201 is inserted in the branch line 332 '' 'of the small diameter portion 33' ''. Finally, the medicine in the syringe 50 enters the human body through the movable closed joint 40, the needle-free connector 30 '' ', the infusion tube 200, and an intravenous system (not shown) connected to the infusion tube 200. The infusion tube 201 can be used by medical personnel to add medicine from the outside. The medicine enters the lower channel 351 '' 'through the branch line 332' '', the infusion tube 200 and the intravenous injection system (not shown) connected to the infusion tube 200. In the human body.

Please refer to FIGS. 31 and 32. FIG. 31 is a perspective view of a needle-free connector of a ninth embodiment of a drug infusion system of the present invention, and FIG. 32 is a view of a needle-free connector of a ninth embodiment of a drug infusion system of the present invention. Sectional view. The difference between the ninth embodiment and the eighth embodiment is that the small-diameter portion of the pinless connector 30`` '' 33 ″ ″ has a laterally extending branch pipe 332 ″ ″, so that the small diameter portion 33 ″ ″ of the needle-free connector 30 ″ ″ is T-shaped. Other than that, the ninth embodiment and the eighth embodiment are used in the same manner, and the description will not be repeated.

The above are only used to explain the preferred embodiments of the present invention, and are not intended to limit the present invention in any form. Therefore, any modification or change related to the present invention made under the same creative spirit Should still be included in the scope of the present invention.

Claims (10)

A drug infusion system includes: a body including a screw connection portion and a puncture portion, and a first channel and a second channel are opened; the screw connection portion of the body is provided with a shaft hole; a bottom end of the puncture portion has a tip The first channel extends axially through the piercing portion and penetrates the bottom end of the piercing portion, the second channel extends axially through the piercing portion and communicates with the shaft hole of the screwing portion of the body and penetrates the piercing portion. Bottom end; a pressure relief device, including a connection structure, a balloon, and a compartment, the connection structure is detachably provided on the body and a first-grade channel is opened, the flow channel communicates with the first channel of the body, and the balloon can be It is detachably provided in the connection structure, the partition is a filter paper or a filter membrane, is provided in the flow channel, and is composed of a waterproof and breathable material with the ability to prevent the passage of liquid and the passage of gas; a needle-free connector, It comprises a screw connection part, a large diameter part, a small diameter part, an upper duct, a lower duct and an elastomer. The screw connection part of the needle-free connector is arranged on the top of the large diameter part of the needle-free connector and open Shaft hole, the large diameter part of the needle-free connector is set between the screw connection part of the needle-free connector and the small diameter part of the needle-free connector and forms a containing space with a partition plate. The accommodating space of the large-diameter portion of the pin connector communicates with the shaft hole of the screw connection portion of the pin-free connector, and the elastic body is disposed in the accommodating space and extends to the shaft of the screw connection portion of the pin-free connector. Hole, and a slit is provided on the top thereof, the upper duct is provided inside the elastic body and an upper channel is opened, the small diameter portion of the needle-free connector and the partition board together form a screw hole, and the lower duct is from the The partition is integrally extended to the screw hole of the small diameter part of the needle-free connector and a lower channel is opened. The lower channel further extends through the partition. The outer side of the large diameter part of the needle-free connector is connected to the needle-free connector. A first-level portion is formed at a contact portion on the outer side of the small-diameter portion, and the screw portion of the body is screwed to the screw hole of the small-diameter portion of the needle-free connector, so that the lower tube of the needle-free connector is inserted in The shaft hole of the screw connection part of the body; and a movable closed joint, including a middle joint and an upper joint Head, the middle joint surrounds a receptacle and includes two clips. The upper joint includes a screw joint, a cylinder, and two clamp arms. The screw joint of the upper joint is provided with an axial hole, and the cylinder is provided with an axial hole. And one side opening, the shaft hole of the cylinder communicates with the shaft hole of the screw joint of the upper joint, the side opening of the cylinder communicates with the shaft hole of the cylinder, and the two clamp arms surround the cylinder; , When the pin-free connector has not been combined with the movable closed connector, the pin-free connector is far away from the middle connector; wherein, when the pin-free connector starts to be combined with the middle connector, the pin-free connector goes toward the The receptacle of the middle joint moves inside until the two clips of the middle joint clamp the step portion of the needle-free connector; and wherein when the middle joint and the upper joint begin to be assembled, the upper joint goes to the middle The direction of the joint moves, the post of the upper joint is stretched out and passes through the slit of the elastomer of the needle-free connector to enter the interior of the elastomer and push the upper duct downwardly until the two clamps of the upper joint The arm clamps the screwed portion of the pin-free connector. The drug infusion system according to item 1 of the scope of patent application, wherein the body is provided with a large-diameter hole extending radially and a small-diameter hole extending radially, and the small-diameter hole communicates with the first channel and the large-diameter hole. Between the holes; wherein, the connection structure of the pressure relief device includes a connecting member, the connecting member includes a plug portion, a ring body and a screw connection portion, the plug portion is inserted in the large diameter hole and a shaft hole is opened , The ring body is provided between the plug-in part and the screw connection part of the connecting member, and a shaft hole and an insert groove are opened, the shaft hole of the ring body communicates with the insert groove, and the partition is provided in the insert groove And a part is located in the shaft hole of the ring body, and a screw hole of the connecting member is provided with a shaft hole; wherein the connection structure of the pressure relief device includes a balloon assembly, the balloon assembly includes a small diameter part, a large The diameter portion, a funnel portion, a front duct, and a rear duct. The small diameter portion of the balloon assembly and a baffle frame a screw hole together, and the screwing portion of the connecting member is screwed to the small portion of the balloon assembly. The screw hole of the diameter part, and the large diameter part of the balloon assembly is provided in the One end of the small-diameter part is far from the connecting member and forms a shaft hole with the baffle. The funnel part is provided at one end of the large-diameter part of the balloon assembly far from the small-diameter part of the balloon assembly and has a funnel-shaped opening The front duct integrally extends from the baffle to the screw hole of the small diameter portion of the balloon assembly, is inserted into the shaft hole of the screwed portion of the connecting member, and a front passage is opened, and the rear duct extends from the baffle. It integrally extends through the shaft hole of the large-diameter portion of the balloon assembly and the funnel-shaped opening of the funnel portion and opens a rear passage. An open end of the balloon is sleeved on the outer side of the rear duct; The axial hole of the plug-in part, the axial hole of the ring body of the connecting member, the front channel of the front tube of the balloon assembly, and the rear channel of the rear tube of the balloon assembly are collectively defined as the flow channel; The connection structure of the pressure device includes a set of rings, which are sleeved on the outer periphery of the open end of the balloon, and the open end of the balloon is fixed on the outer side of the rear duct and inside the large diameter portion of the balloon assembly Between the sidewalls. According to the pharmaceutical infusion system according to item 2 of the scope of the patent application, wherein at least a part of the insert groove penetrates the outer peripheral surface of the ring body to form an arc-shaped gap, and the partition layer can enter and exit the insert groove through the arc-shaped gap. The pharmaceutical infusion system according to item 1 of the scope of patent application, wherein the two clips are respectively disposed on two opposite sides of the outer peripheral surface of the middle joint, the middle joint includes two convex portions, and the two convex portions are respectively disposed in the middle. The outer peripheral surface of the joint is opposite to the other two sides and extends axially. Each convex portion is provided with a longitudinally extending long groove. The top of the two long grooves is open and the bottom is closed. The inner side communicates with the receiving groove. When the joint starts to combine with the upper joint, the upper joint moves in the direction of the middle joint, and the two clamp arms are slid in the two long grooves. The drug infusion system according to item 4 of the scope of patent application, wherein the upper joint has a top wall and a ring wall, and the top wall and the ring wall together form a container, and the screw joint of the upper joint is provided on the The upper surface of the top wall, the cylinder is located on the lower surface of the top wall and is located in the container. The two opposite sides of the ring wall are respectively provided with two vertical grooves penetrating the bottom of the ring wall. The width of the two vertical grooves is larger than the two. The width of the convex part, the two clamping arms are provided on the lower surface of the top wall, are respectively located in the two longitudinal grooves, and the two clamping blocks protrude from the inner sides thereof; when the needle-free connector has not been combined with the movable closed joint , The bottom of the clamp block of the two clamp arms abuts against the top of the middle joint, and at the same time, the part of the two clamp arms located below the clamp block clamps the middle joint; when the middle joint and the upper joint begin to combine, the The two convex parts are slid in the two longitudinal grooves respectively, until the clamping block of the two clamping arms abuts the screw connection part of the pin-free connector, at this time, the part of the two clamping arms located under the clamping block is clamped. The screw connection of the pin-free connector. The pharmaceutical infusion system according to item 5 of the scope of patent application, wherein the middle joint includes two limiting blocks, and the two limiting blocks are respectively disposed on two opposite sides of the outer peripheral surface of the middle joint and above the two clamps. The two opposite sides of the annular wall are respectively provided with two sliding grooves, the two sliding grooves do not penetrate the bottom of the annular wall, and the two limiting blocks are respectively slidably disposed in the two sliding grooves; when the needle-free connector has not been When combined with the movable closed joint, the two limiting blocks abut against the bottom ends of the two slide grooves; when the two clamping arms clamp the screw connection portion of the needle-free connector, the two limiting blocks abut On the lower surface of the top wall of the upper joint. The pharmaceutical infusion system according to item 6 of the scope of patent application, wherein two opposite sides of the outer peripheral surface of the middle joint are respectively provided with two cut grooves penetrating through the bottom thereof, and the two clips respectively extend axially in the two cut grooves and the Two clip blocks protrude from the inner side respectively; when the needle-free connector and the middle connector start to be combined, the needle-free connector moves to the inside of the receptacle of the middle connector until the clip block of the two clip body clamps the needle-free connection Up to the class ministry. The drug infusion system according to item 1 of the scope of patent application, wherein the movable closed joint includes a plug body, the plug body is provided in the receptacle of the middle joint and has a shaft hole and a slit; when the needle-free connection When the adapter has not been combined with the movable closed joint, the cylinder of the upper joint is located in the shaft hole of the plug; when the two clips of the middle joint clamp the step portion of the needle-free connector, the plug's The bottom abuts against the top of the elastomer of the needle-free connector; when the middle joint of the movable closed joint and the upper joint begin to combine, the upper joint moves in the direction of the middle joint, and the cylinders of the upper joint sequentially Open and pass through the slit of the plug body and the slit of the elastomer of the needle-free connector to enter the interior of the elastomer. The pharmaceutical infusion system according to item 8 of the scope of patent application, wherein the upper joint has a top wall and a ring wall, and the top wall and the ring wall jointly form a container, and the screw joint portion of the upper joint is provided on the The upper surface of the top wall, the cylinder is located on the lower surface of the top wall and is located in the containing chamber; the drug infusion system further includes a sheath provided in the containing chamber, and the top end is against the top wall of the upper joint; The bottom surface of the lower part abuts against the plug body, and the post body is covered inside. The pharmaceutical infusion system according to item 1 of the scope of patent application, wherein the two clips are respectively disposed on two opposite sides of the outer peripheral surface of the middle joint, and two longitudinally extending lengths are provided on the other two sides of the outer peripheral surface of the middle joint. The top of the two long grooves is open, the bottom is closed, and the inner side communicates with the containing groove; the middle joint includes two bosses, and the two bosses approach the two long grooves from the outer side of the middle joint, respectively. The bottom wall extends laterally; wherein, the upper joint has a top wall and a ring wall, the top wall and the ring wall together constitute a container, and the screw joint of the upper joint is provided on the upper surface of the top wall, The pillar is disposed on the lower surface of the top wall and is located in the containing chamber. Two opposite sides of the ring wall are respectively provided with two vertical grooves penetrating the bottom thereof. The width of the two vertical grooves is equal to the width of the two bosses. Two clamp arms are provided on the lower surface of the top wall, respectively located in the two longitudinal grooves, and two clamp blocks are protruded from the inner sides of the two longitudinal grooves, wherein the medicine infusion system further includes a sleeve, which is sleeved on the upper joint. The two clamping arms, and the inner side of the two clamping arms protrude from the two convex bodies, the two convex The body abuts on the outer side of the two clamping arms, and its position corresponds to the position of the clamping block of the two clamping arms; wherein, when the needle-free connector has not been combined with the movable closed joint, the two convex bodies provide a The force is given to the two clamp arms such that the bottom of the clamp block of the two clamp arms abuts against the top of the middle joint, and the portion of the two clamp arms located below the clamp block securely clamps the middle joint by the force; Wherein, after the combination of the needle-free connector and the middle joint is completed, before the middle joint and the upper joint begin to be assembled, the sleeve moves in the direction of the middle joint and disengages from the two clamp arms until the two convex Until the body abuts the two bosses, the two clamping arms can be expanded outward at this time, so that the clamping block of the two clamping arm is separated from the top of the middle joint, and the part of the two clamping arm located below the clamping block is no longer Clamp the middle joint; when the middle joint and the upper joint begin to combine, the upper joint moves in the direction of the middle joint, and the two clamp arms are slid in the two long grooves until the two clamp arms The clamping block abuts on the screwing part of the pin-free connector. The two portions of the clamp arm is positioned below the clamp block sandwiched threaded portion of the needle-free connector.