TWI461191B - 單種或組合型植物-大麻素於治療癲癇的用途 - Google Patents

單種或組合型植物-大麻素於治療癲癇的用途 Download PDF

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Publication number
TWI461191B
TWI461191B TW099121811A TW99121811A TWI461191B TW I461191 B TWI461191 B TW I461191B TW 099121811 A TW099121811 A TW 099121811A TW 99121811 A TW99121811 A TW 99121811A TW I461191 B TWI461191 B TW I461191B
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Taiwan
Prior art keywords
seizures
thcv
cbd
animals
ptz
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TW099121811A
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English (en)
Chinese (zh)
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TW201105318A (en
Inventor
班 懷利
蓋瑞 史蒂芬
克拉蕊 威廉斯
傑佛瑞 蓋伊
史蒂芬 懷特
菊地哲朗
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Gw伐瑪有限公司
大塚製藥股份有限公司
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Application filed by Gw伐瑪有限公司, 大塚製藥股份有限公司 filed Critical Gw伐瑪有限公司
Publication of TW201105318A publication Critical patent/TW201105318A/zh
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/658—Medicinal preparations containing organic active ingredients o-phenolic cannabinoids, e.g. cannabidiol, cannabigerolic acid, cannabichromene or tetrahydrocannabinol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A61P25/10—Antiepileptics; Anticonvulsants for petit-mal
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A61P25/12—Antiepileptics; Anticonvulsants for grand-mal
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2121/00—Preparations for use in therapy

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Pain & Pain Management (AREA)
  • Medical Informatics (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Plant Substances (AREA)
TW099121811A 2009-07-03 2010-07-02 單種或組合型植物-大麻素於治療癲癇的用途 TWI461191B (zh)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB0911580A GB2471523A (en) 2009-07-03 2009-07-03 Use of tetrahydrocannibivarin (THCV) and optionally cannabidiol (CBD) in the treatment of epilepsy

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TW201105318A TW201105318A (en) 2011-02-16
TWI461191B true TWI461191B (zh) 2014-11-21

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GB0911580D0 (en) 2009-08-12
EP2448637B1 (en) 2014-03-12
WO2011001169A1 (en) 2011-01-06
CA2766082A1 (en) 2011-01-06
HRP20140398T4 (hr) 2022-10-14
MY156759A (en) 2016-03-31
PL2448637T5 (pl) 2022-10-03
JP2012532093A (ja) 2012-12-13
ES2460623T3 (es) 2014-05-14
AU2010267775A1 (en) 2012-02-23
EP2448637A1 (en) 2012-05-09
RU2012103603A (ru) 2013-08-10
SG176914A1 (en) 2012-01-30
PT2448637E (pt) 2014-05-27
AR077448A1 (es) 2011-08-31
CA3040410C (en) 2023-03-28
ZA201200373B (en) 2012-09-26
AU2010267775B2 (en) 2016-10-06
AU2010267775C1 (en) 2020-02-27
NZ597704A (en) 2014-05-30
CA2766082C (en) 2019-06-11
US9522123B2 (en) 2016-12-20
MX2012000257A (es) 2012-01-27
HRP20140398T1 (hr) 2014-06-20
IN2012DN00804A (cg-RX-API-DMAC10.html) 2015-06-26
GB201010897D0 (en) 2010-08-11
SI2448637T2 (sl) 2022-10-28
NZ620838A (en) 2015-08-28
US20150335590A1 (en) 2015-11-26
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