TWI458478B - 用於代謝症候群與第２型糖尿病的反式氯米芬 - Google Patents

用於代謝症候群與第２型糖尿病的反式氯米芬 Download PDF

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Publication number
TWI458478B
TWI458478B TW098137209A TW98137209A TWI458478B TW I458478 B TWI458478 B TW I458478B TW 098137209 A TW098137209 A TW 098137209A TW 98137209 A TW98137209 A TW 98137209A TW I458478 B TWI458478 B TW I458478B
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TW
Taiwan
Prior art keywords
clomiphene
trans
individual
levels
serum
Prior art date
Application number
TW098137209A
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English (en)
Chinese (zh)
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TW201031400A (en
Inventor
As Andre Van
Original Assignee
Repros Therapeutics Inc
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=41404260&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=TWI458478(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Repros Therapeutics Inc filed Critical Repros Therapeutics Inc
Publication of TW201031400A publication Critical patent/TW201031400A/zh
Application granted granted Critical
Publication of TWI458478B publication Critical patent/TWI458478B/zh

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

Landscapes

  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Diabetes (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Engineering & Computer Science (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
TW098137209A 2008-11-07 2009-11-03 用於代謝症候群與第２型糖尿病的反式氯米芬 TWI458478B (zh)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US11245808P 2008-11-07 2008-11-07

Publications (2)

Publication Number Publication Date
TW201031400A TW201031400A (en) 2010-09-01
TWI458478B true TWI458478B (zh) 2014-11-01

Family

ID=41404260

Family Applications (2)

Application Number Title Priority Date Filing Date
TW098137209A TWI458478B (zh) 2008-11-07 2009-11-03 用於代謝症候群與第２型糖尿病的反式氯米芬
TW103133928A TW201500041A (zh) 2008-11-07 2009-11-03 用於代謝症候群與第２型糖尿病的反式氯米芬

Family Applications After (1)

Application Number Title Priority Date Filing Date
TW103133928A TW201500041A (zh) 2008-11-07 2009-11-03 用於代謝症候群與第２型糖尿病的反式氯米芬

Country Status (4)

Country Link
AR (1) AR074302A1 (fr)
CL (1) CL2009002036A1 (fr)
TW (2) TWI458478B (fr)
WO (1) WO2010054248A1 (fr)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2453337C (fr) 2001-07-09 2012-08-28 Zonagen, Inc. Methodes et materiaux destines au traitement de la deficience en testosterone chez l'homme
UA113291C2 (xx) 2011-08-04 2017-01-10 Метаболіти транскломіфену і їх застосування
CA2864104A1 (fr) * 2012-02-14 2013-08-22 Repros Therapeutics Inc. Modulateurs selectifs des recepteurs d'ƒstrogenes a demi-vies courtes et leurs utilisations
BR112015002288A2 (pt) * 2012-08-21 2017-07-04 Repros Therapeutics Inc formulações de trans-clomifeno e usos das mesmas
AU2013338311A1 (en) 2012-11-02 2015-05-14 Repros Therapeutics Inc. Trans-clomiphene for use in cancer therapy
JP2019506425A (ja) * 2016-02-25 2019-03-07 アスペン パーク ファーマシューティカルズ，インコーポレイティド クロミフェン異性体の経口剤形および続発性性腺機能低下症を治療するために経口剤形を使用する方法
CN108463453A (zh) 2016-04-22 2018-08-28 意大利合成制造有限公司 用于制备具有针状晶体习性的柠檬酸恩氯米芬的方法

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7067557B2 (en) * 2000-05-26 2006-06-27 Harry Fisch Methods of treating androgen deficiency in men using selective antiestrogens

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2597700A1 (fr) * 2005-03-22 2006-09-28 Repros Therapeutics Inc. Schemas posologiques pour le trans-clomiphene
EP1829534A1 (fr) * 2006-03-02 2007-09-05 Laboratorios Del Dr. Esteve, S.A. Utilisation d'un composé ayant une activité de liaison aux récepteurs sigma pour le traitement du syndrome métabolique
JP5558358B2 (ja) * 2007-10-16 2014-07-23 レプロス セラピューティクス インコーポレイティド メタボリック症候群用のｔｒａｎｓ−クロミフェン

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7067557B2 (en) * 2000-05-26 2006-06-27 Harry Fisch Methods of treating androgen deficiency in men using selective antiestrogens

Also Published As

Publication number Publication date
AR074302A1 (es) 2011-01-05
WO2010054248A1 (fr) 2010-05-14
TW201031400A (en) 2010-09-01
CL2009002036A1 (es) 2010-02-05
TW201500041A (zh) 2015-01-01

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JP5856652B2 (ja) メタボリック症候群用のｔｒａｎｓ−クロミフェン
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JP2021046448A (ja) 癌療法における使用のためのトランス−クロミフェン
CA2595363C (fr) Methodes et mareriaux a base de trans-clomiphene permettant de traiter la sterilite masculine
US20130165524A1 (en) Trans-clomiphene for metabolic syndrome
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