TWI369350B - Process for producing compound having npyy5 receptor antagonism and useful crystals - Google Patents

Process for producing compound having npyy5 receptor antagonism and useful crystals

Info

Publication number
TWI369350B
TWI369350B TW098115070A TW98115070A TWI369350B TW I369350 B TWI369350 B TW I369350B TW 098115070 A TW098115070 A TW 098115070A TW 98115070 A TW98115070 A TW 98115070A TW I369350 B TWI369350 B TW I369350B
Authority
TW
Taiwan
Prior art keywords
producing compound
receptor antagonism
npyy5 receptor
useful crystals
crystals
Prior art date
Application number
TW098115070A
Other languages
English (en)
Other versions
TW200948783A (en
Inventor
Yoshihide Sugata
Yutaka Ide
Teruo Sakata
Sohei Omura
Original Assignee
Shionogi & Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shionogi & Co filed Critical Shionogi & Co
Publication of TW200948783A publication Critical patent/TW200948783A/zh
Application granted granted Critical
Publication of TWI369350B publication Critical patent/TWI369350B/zh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72—Nitrogen atoms
    • C07D213/75—Amino or imino radicals, acylated by carboxylic or carbonic acids, or by sulfur or nitrogen analogues thereof, e.g. carbamates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/01—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms
    • C07C311/02—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
    • C07C311/07—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton having the nitrogen atom of at least one of the sulfonamide groups bound to a carbon atom of a ring other than a six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
TW098115070A 2008-05-08 2009-05-07 Process for producing compound having npyy5 receptor antagonism and useful crystals TWI369350B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2008122154 2008-05-08

Publications (2)

Publication Number Publication Date
TW200948783A TW200948783A (en) 2009-12-01
TWI369350B true TWI369350B (en) 2012-08-01

Family

ID=41264672

Family Applications (1)

Application Number Title Priority Date Filing Date
TW098115070A TWI369350B (en) 2008-05-08 2009-05-07 Process for producing compound having npyy5 receptor antagonism and useful crystals

Country Status (14)

Country Link
US (1) US20110060145A1 (zh)
EP (1) EP2275410A4 (zh)
JP (2) JP4756565B2 (zh)
KR (1) KR101278359B1 (zh)
CN (1) CN102015647A (zh)
AR (1) AR071695A1 (zh)
AU (1) AU2009245113A1 (zh)
CA (1) CA2723133A1 (zh)
CL (1) CL2009001088A1 (zh)
MX (1) MX2010011835A (zh)
RU (1) RU2010144412A (zh)
TW (1) TWI369350B (zh)
WO (1) WO2009136617A1 (zh)
ZA (1) ZA201007364B (zh)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102438623A (zh) * 2009-03-19 2012-05-02 盐野义制药株式会社 含有npyy5受体拮抗剂的固体制剂

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SI2014285T1 (sl) * 1999-11-26 2010-08-31 Shionogi & Co Antagonisti NPYY5
WO2003076374A1 (fr) * 2002-03-12 2003-09-18 Shionogi & Co., Ltd. Procede de production de derive d'acide trans-4-amino-1-cyclohexanecarboxylique
JP4636525B2 (ja) * 2004-03-12 2011-02-23 塩野義製薬株式会社 トランス−４−アミノ−１−シクロヘキサンカルボン酸エチルエステルの塩およびその製造方法
CA2603418A1 (en) * 2005-03-31 2006-10-12 Shionogi & Co., Ltd. Method for producing sulfamate-carboxylate derivatives
US20100076081A1 (en) * 2006-09-28 2010-03-25 Sohei Omura Method for producing salt of 4-sulfinylamino-1-cyclohexanecarboxylic acid

Also Published As

Publication number Publication date
JPWO2009136617A1 (ja) 2011-09-08
KR20110004898A (ko) 2011-01-14
EP2275410A1 (en) 2011-01-19
KR101278359B1 (ko) 2013-06-25
CA2723133A1 (en) 2009-11-12
JP5234856B2 (ja) 2013-07-10
AR071695A1 (es) 2010-07-07
RU2010144412A (ru) 2012-06-20
EP2275410A4 (en) 2012-05-09
CN102015647A (zh) 2011-04-13
CL2009001088A1 (es) 2011-06-17
MX2010011835A (es) 2010-11-25
JP4756565B2 (ja) 2011-08-24
US20110060145A1 (en) 2011-03-10
WO2009136617A1 (ja) 2009-11-12
AU2009245113A1 (en) 2009-11-12
TW200948783A (en) 2009-12-01
ZA201007364B (en) 2012-01-25
JP2011178790A (ja) 2011-09-15

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Legal Events

Date Code Title Description
MM4A Annulment or lapse of patent due to non-payment of fees