TWI324935B - - Google Patents
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- TWI324935B TWI324935B TW91118344A TW91118344A TWI324935B TW I324935 B TWI324935 B TW I324935B TW 91118344 A TW91118344 A TW 91118344A TW 91118344 A TW91118344 A TW 91118344A TW I324935 B TWI324935 B TW I324935B
- Authority
- TW
- Taiwan
- Prior art keywords
- sleep
- melatonin
- agent
- quality
- agents
- Prior art date
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- YJPIGAIKUZMOQA-UHFFFAOYSA-N Melatonin Natural products COC1=CC=C2N(C(C)=O)C=C(CCN)C2=C1 YJPIGAIKUZMOQA-UHFFFAOYSA-N 0.000 claims description 72
- 229960003987 melatonin Drugs 0.000 claims description 72
- DRLFMBDRBRZALE-UHFFFAOYSA-N melatonin Chemical compound COC1=CC=C2NC=C(CCNC(C)=O)C2=C1 DRLFMBDRBRZALE-UHFFFAOYSA-N 0.000 claims description 72
- 230000007958 sleep Effects 0.000 claims description 68
- 239000003795 chemical substances by application Substances 0.000 claims description 36
- 230000003860 sleep quality Effects 0.000 claims description 26
- 239000003814 drug Substances 0.000 claims description 19
- 238000000034 method Methods 0.000 claims description 13
- 238000013265 extended release Methods 0.000 claims description 11
- 230000006872 improvement Effects 0.000 claims description 9
- 239000002249 anxiolytic agent Substances 0.000 claims description 7
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims description 7
- 229940088597 hormone Drugs 0.000 claims description 7
- 239000005556 hormone Substances 0.000 claims description 7
- 150000001875 compounds Chemical class 0.000 claims description 6
- VYFYYTLLBUKUHU-UHFFFAOYSA-N dopamine Chemical compound NCCC1=CC=C(O)C(O)=C1 VYFYYTLLBUKUHU-UHFFFAOYSA-N 0.000 claims description 6
- 239000000932 sedative agent Substances 0.000 claims description 6
- 239000000164 antipsychotic agent Substances 0.000 claims description 5
- 239000003326 hypnotic agent Substances 0.000 claims description 5
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- JDSHMPZPIAZGSV-UHFFFAOYSA-N melamine Chemical compound NC1=NC(N)=NC(N)=N1 JDSHMPZPIAZGSV-UHFFFAOYSA-N 0.000 claims 1
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- 239000005557 antagonist Substances 0.000 description 11
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- TZWKUQDQKPYNLL-UHFFFAOYSA-N cloforex Chemical compound CCOC(=O)NC(C)(C)CC1=CC=C(Cl)C=C1 TZWKUQDQKPYNLL-UHFFFAOYSA-N 0.000 description 3
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- SFLSHLFXELFNJZ-QMMMGPOBSA-N (-)-norepinephrine Chemical compound NC[C@H](O)C1=CC=C(O)C(O)=C1 SFLSHLFXELFNJZ-QMMMGPOBSA-N 0.000 description 2
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Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| TW91118344A TWI324935B (enrdf_load_stackoverflow) | 2002-08-09 | 2002-08-09 |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| TW91118344A TWI324935B (enrdf_load_stackoverflow) | 2002-08-09 | 2002-08-09 |
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|---|---|
| TWI324935B true TWI324935B (enrdf_load_stackoverflow) | 2010-05-21 |
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| Application Number | Title | Priority Date | Filing Date |
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| TW91118344A TWI324935B (enrdf_load_stackoverflow) | 2002-08-09 | 2002-08-09 |
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| Country | Link |
|---|---|
| TW (1) | TWI324935B (enrdf_load_stackoverflow) |
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2002
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