TWI242431B - Pharmaceutical compositions for treating pulmonary diseases - Google Patents

Pharmaceutical compositions for treating pulmonary diseases Download PDF

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Publication number
TWI242431B
TWI242431B TW089123039A TW89123039A TWI242431B TW I242431 B TWI242431 B TW I242431B TW 089123039 A TW089123039 A TW 089123039A TW 89123039 A TW89123039 A TW 89123039A TW I242431 B TWI242431 B TW I242431B
Authority
TW
Taiwan
Prior art keywords
dose
clinical
fev
asthma
cilomalast
Prior art date
Application number
TW089123039A
Other languages
English (en)
Chinese (zh)
Inventor
Peter N Goodfellow
Richard Nieman
Theodore J Torphy
Original Assignee
Smithkline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Corp filed Critical Smithkline Beecham Corp
Application granted granted Critical
Publication of TWI242431B publication Critical patent/TWI242431B/zh

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
TW089123039A 1999-11-02 2000-11-22 Pharmaceutical compositions for treating pulmonary diseases TWI242431B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US16315899P 1999-11-02 1999-11-02

Publications (1)

Publication Number Publication Date
TWI242431B true TWI242431B (en) 2005-11-01

Family

ID=22588737

Family Applications (1)

Application Number Title Priority Date Filing Date
TW089123039A TWI242431B (en) 1999-11-02 2000-11-22 Pharmaceutical compositions for treating pulmonary diseases

Country Status (29)

Country Link
EP (1) EP1225866A4 (xx)
JP (1) JP2003513028A (xx)
KR (1) KR20020057988A (xx)
CN (1) CN1387404A (xx)
AP (1) AP2002002496A0 (xx)
AR (1) AR029189A1 (xx)
AU (1) AU1357501A (xx)
BG (1) BG106748A (xx)
BR (1) BR0015270A (xx)
CA (1) CA2388333A1 (xx)
CO (1) CO5261512A1 (xx)
CZ (1) CZ20021512A3 (xx)
DZ (1) DZ3225A1 (xx)
EA (1) EA200200518A1 (xx)
EC (1) ECSP003747A (xx)
HK (1) HK1049107A1 (xx)
HU (1) HUP0203152A3 (xx)
IL (1) IL149367A0 (xx)
MA (1) MA26841A1 (xx)
MX (1) MXPA02004350A (xx)
NO (1) NO20022057L (xx)
OA (1) OA12076A (xx)
PE (1) PE20011005A1 (xx)
PL (1) PL355261A1 (xx)
SK (1) SK7592002A3 (xx)
TR (1) TR200201211T2 (xx)
TW (1) TWI242431B (xx)
WO (1) WO2001032127A2 (xx)
ZA (1) ZA200203435B (xx)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EA008108B1 (ru) * 2001-09-19 2007-04-27 Алтана Фарма Аг Комбинация нспвлс и ингибитора pde-4
US20040259863A1 (en) * 2001-10-31 2004-12-23 Hans-Michael Eggenweiler Type 4 phosphodiesterase inhibitors and uses thereof
UA82323C2 (uk) * 2002-08-09 2008-04-10 Меда Фарма Гмбх & Ко. Кг Нова комбінація глюкокортикоїду та pde-інгібітору для лікування респіраторних захворювань, алергічних захворювань, астми та хронічних обструктивних легеневих захворювань
TW200410923A (en) * 2002-10-17 2004-07-01 Ono Pharmaceutical Co Therapeutic agent for chronic obstructive pulmonary disease
EP1616569A1 (en) * 2003-03-31 2006-01-18 Kyowa Hakko Kogyo Co., Ltd. Medicinal composition
US20050026883A1 (en) * 2003-07-31 2005-02-03 Robinson Cynthia B. Combination of dehydroepiandrosterone or dehydroepiandrosterone-sulfate with a PDE-4 inhibitor for treatment of asthma or chronic obstructive pulmonary disease
WO2006041121A1 (ja) * 2004-10-13 2006-04-20 Kyowa Hakko Kogyo Co., Ltd. 慢性皮膚疾患の治療および／または予防剤
WO2007045980A1 (en) * 2005-10-19 2007-04-26 Ranbaxy Laboratories Limited Compositions of phosphodiesterase type iv inhibitors
CN105381524A (zh) 2010-01-05 2016-03-09 微剂量治疗技术公司 吸入设备和方法
WO2015063669A1 (en) 2013-10-30 2015-05-07 Wockhardt Limited Pharmaceutical compositions comprising combination of roflumilast and acebrophylline or pharmaceutically acceptable salts thereof

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK0710109T3 (da) * 1993-06-18 2005-01-03 Smithkline Beecham Corp Fremgangsmåde til identifikation af en PDE IV inhibitor
DE4332041C2 (de) * 1993-09-21 1997-12-11 Rentschler Arzneimittel Verwendung von Pentoxifyllin bei bestimmten Lungenerkrankungen
PE44995A1 (es) * 1994-01-27 1995-12-18 Schering Corp Furoato de mometasona para el tratamiento de las enfermedades pulmonares y de las vias respiratorias
SE9801368D0 (sv) * 1998-04-20 1998-04-20 Astra Ab New use

Also Published As

Publication number Publication date
JP2003513028A (ja) 2003-04-08
CO5261512A1 (es) 2003-03-31
EP1225866A2 (en) 2002-07-31
CN1387404A (zh) 2002-12-25
DZ3225A1 (fr) 2001-05-10
WO2001032127A3 (en) 2001-12-06
TR200201211T2 (tr) 2002-08-21
PL355261A1 (en) 2004-04-05
CZ20021512A3 (cs) 2003-04-16
KR20020057988A (ko) 2002-07-12
HK1049107A1 (zh) 2003-05-02
MA26841A1 (fr) 2004-12-20
IL149367A0 (en) 2002-11-10
EA200200518A1 (ru) 2002-10-31
OA12076A (en) 2006-05-04
ZA200203435B (en) 2003-06-25
HUP0203152A3 (en) 2004-06-28
NO20022057L (no) 2002-06-27
ECSP003747A (es) 2002-05-23
BG106748A (en) 2003-02-28
SK7592002A3 (en) 2002-11-06
WO2001032127A2 (en) 2001-05-10
CA2388333A1 (en) 2001-05-10
MXPA02004350A (es) 2002-11-07
BR0015270A (pt) 2002-06-18
NO20022057D0 (no) 2002-04-30
EP1225866A4 (en) 2004-04-21
PE20011005A1 (es) 2001-09-28
AR029189A1 (es) 2003-06-18
AU1357501A (en) 2001-05-14
HUP0203152A2 (hu) 2003-01-28
AP2002002496A0 (en) 2002-06-30

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Legal Events

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MM4A Annulment or lapse of patent due to non-payment of fees